Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

C3_SMALL_INTESTINE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C17
  • Hospital discharge: ICD-9 152
  • Hospital discharge: ICD-8 152
  • Cause of death: ICD-10 C17
  • Cause of death: ICD-9 152
  • Cause of death: ICD-8 152
  • Cancer registry: Topography ICD-O-3 C17
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

1056

4. Check minimum number of events

None

1056

5. Include endpoints

None

1056

6. Filter based on genotype QC (FinnGen only)

1056

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1056 488 568
Unadjusted period prevalence (%) 0.21 0.17 0.25
Median age at first event (years) 64.15 61.99 66.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
676
Matched controls
6759
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
+∞
323.0
298
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
348
*
JFB00
NOMESCO Finland
Partial resection of small intestine
242.9
318.4
307
23
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
360.9
229.8
220
9
JN4BD
NOMESCO Finland
Extensive body CT
30.4
188.1
260
136
C17.2
ICD-10 Finland
Malignant neoplasm: Ileum
+∞
175.9
161
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
46.7
159.2
195
58
8240/3-C17.9
ICD-O-3
Neuroendocrine tumor, NOS, of small intestine, NOS
+∞
149.6
138
*
H01CB03
ATC
lanreotide; parenteral
+∞
144.0
133
*
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
131.6
122
*
H01CB02
ATC
octreotide; parenteral
1497.8
130.7
123
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
122.7
114
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
11.7
117.2
240
303
8240/3-C17.2
ICD-O-3
Neuroendocrine tumor, NOS, of ileum
+∞
114.9
107
*
A03FA01
ATC
metoclopramide; systemic, rectal
9.8
112.9
261
409
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
111.6
104
*
JN4AD
NOMESCO Finland
Body CT examination
21.8
111.1
168
101
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
95.1
89
*
A04AA02
ATC
granisetron; systemic, transdermal
474.6
86.1
84
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
24.2
85.8
124
62
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
14.0
84.5
152
137
L01BC06
ATC
capecitabine; oral
+∞
80.9
76
*
H02AB02
ATC
dexamethasone; systemic
34.5
78.9
103
35
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
20.4
73.4
112
65
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
29.5
72.9
99
39
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
71.1
67
*
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
+∞
71.1
67
*
B01AB05
ATC
enoxaparin; parenteral
4.6
70.2
344
1252
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
+∞
70.0
66
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.5
68.9
345
1277
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
68.9
65
*
C17.1
ICD-10 Finland
Malignant neoplasm: Jejunum
+∞
67.9
64
*
JN4CD
NOMESCO Finland
Very extensive body CT
25.5
65.7
93
42
Z51.5
ICD-10 Finland
Palliative care
22.2
64.9
96
50
D77
ICPC
Malignant digestive neopl other/NOS
+∞
63.5
60
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.1
63.0
357
1445
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
666.6
62.9
61
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
61.4
58
*
JFB30
NOMESCO Finland
Right hemicolectomy
57.3
61.4
72
14
WX408
NOMESCO Finland
General anesthesy, balanced
4.5
61.3
281
928
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
23.8
59.7
86
41
C17.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of small intestine
+∞
58.2
55
*
JAH00
NOMESCO Finland
Laparotomy
19.4
56.4
87
51
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
26.2
55.1
77
33
UJF32
NOMESCO Finland
Coloscopy
3.9
54.8
299
1130
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
559.5
53.2
52
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.9
53.0
284
1050
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
+∞
52.8
50
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
51.7
49
*
8249/3-C17.9
ICD-O-3
Neuroendocrine tumor, grade 2 of small intestine, NOS
+∞
51.7
49
*
A04AA01
ATC
ondansetron; systemic, rectal
16.0
51.3
85
60
8249/3-C17.2
ICD-O-3
Neuroendocrine tumor, grade 2 of ileum
+∞
49.6
47
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
32.8
45.7
60
20
JN3AD
NOMESCO Finland
Abdominal CT examination
6.7
45.5
125
222
B01AB10
ATC
tinzaparin; parenteral
8.7
45.4
103
137
L03AA02
ATC
filgrastim; parenteral
105.4
45.4
49
5
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
45.3
43
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
45.3
43
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.4
44.3
148
335
L03AA13
ATC
pegfilgrastim; parenteral
+∞
44.2
42
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
229.0
42.4
43
*
N02AA05
ATC
oxycodone; systemic
4.7
42.4
163
428
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
42.1
40
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
94.0
40.3
44
5
A09AA02
ATC
multienzymes (lipase, protease etc.)
18.3
39.7
62
37
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
50.3
39.3
47
10
8140/3-C17.0
ICD-O-3
Adenocarcinoma, NOS, of duodenum
+∞
38.9
37
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.2
38.8
99
157
JAH01
NOMESCO Finland
Laparoscopy
12.5
38.2
70
62
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
38.1
152
410
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
36.6
213
795
A79
ICPC
Malignancy NOS
133.9
36.1
38
*
JKA20
NOMESCO Finland
Cholecystectomy
10.7
36.0
71
73
JLC30
NOMESCO Finland
Pancreatoduodenectomy
+∞
34.7
33
*
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
60.5
34.6
40
7
115
Kela drug reimbursment
Breast cancer
+∞
33.6
32
*
PJA12
NOMESCO Finland
Sentinel node biopsy
342.8
33.2
33
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
24.6
32.7
46
20
302
Kela drug reimbursment
Interferon alfa
+∞
32.6
31
*
UJF30
NOMESCO Finland
Ileoscopy through colon
4.6
32.5
123
311
189
Kela drug reimbursment
Imatinib
+∞
31.5
30
*
WX402
NOMESCO Finland
General anaesthesia
4.0
31.4
142
425
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
22.8
31.3
45
21
WW500
NOMESCO Finland
Blood transfusion
11.9
31.1
58
53
ZXE10
NOMESCO Finland
More than one and less than three hours
2.7
31.1
298
1518
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
30.4
29
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
30.4
29
*
XX3DW
NOMESCO Finland
Time consuming IT work
6.6
30.4
82
139
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
16.6
29.9
48
31
116
Kela drug reimbursment
Prostate cancer
+∞
29.4
28
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
29.4
28
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
9.4
29.4
62
72
A02BC02
ATC
pantoprazole; systemic
2.6
29.2
490
3375
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
83.9
29.0
32
*
UJF92
NOMESCO Finland
Capsular endoscopy
12.7
28.9
52
44
JFB20
NOMESCO Finland
Ileocaecal resection
51.0
28.6
34
7
R4190
NOMESCO Finland
Nutritional therapy
12.1
28.3
52
46
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
28.3
27
*
T73
ICPC
Neoplasm endocrine other/unspecified
292.8
28.0
28
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.8
27.9
50
42
C10AC01
ATC
colestyramine; oral
8.9
27.7
60
73
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
27.3
26
*
L01AX03
ATC
temozolomide; systemic
+∞
27.3
26
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
27.3
351
2062
D64.9
ICD-10 Finland
Anaemia, unspecified
3.8
26.2
124
381
L01XE01
ATC
[U] imatinib; oral
+∞
26.2
25
*
WZC30
NOMESCO Finland
Teaching
3.8
25.9
121
368
L03AB05
ATC
interferon alfa-2b; parenteral
97.2
25.8
28
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
23.7
25.5
36
16
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.8
25.0
73
137
ZXE20
NOMESCO Finland
More than three and less than five hours
3.4
24.6
133
453
K56.7
ICD-10 Finland
Ileus, unspecified
13.5
24.2
42
33
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
24.1
23
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
24.1
23
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
24.1
23
*
8140/3-C17.9
ICD-O-3
Adenocarcinoma, NOS, of small intestine, NOS
+∞
23.0
22
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
23.0
22
*
9680/3-C17.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of small intestine, NOS
+∞
23.0
22
*
8246/3-C17.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of small intestine, NOS
+∞
23.0
22
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
41.6
22.8
28
7
ZXD05
NOMESCO Finland
Urgent procedure
2.4
22.8
251
1323
JF1BD
NOMESCO Finland
Very extensive small bowel CT
28.4
22.4
30
11
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.6
22.4
46
51
D70.82
ICD-10 Finland
Drug-induced neutropenia
53.9
22.2
26
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.2
22.1
89
236
JN7SN
NOMESCO Finland
Somatostatin receptor SPECT
+∞
22.0
21
*
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
+∞
22.0
21
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
118.8
21.7
23
*
8240/3-C17.0
ICD-O-3
Neuroendocrine tumor, NOS, of duodenum
+∞
20.9
20
*
8936/3-C17.9
ICD-O-3
Gastrointestinal stromal tumor of small intestine, NOS
+∞
20.9
20
*
WF002
NOMESCO Finland
Radical radiotherapy
43.1
20.6
25
6
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
75.8
19.8
22
*
ZX120
NOMESCO Finland
Intravenous
3.8
19.6
87
251
HAB40
NOMESCO Finland
Wedge excision of mammary gland
41.4
19.6
24
6
L02BG04
ATC
letrozole; oral
47.5
19.3
23
5
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.9
19.1
83
235
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
18.8
18
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
18.8
18
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
102.9
18.6
20
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
18.6
114
421
XW000
NOMESCO Finland
Bone marrow biopsy
5.7
18.2
53
99
L02AE02
ATC
leuprorelin; implant, parenteral
27.6
17.9
24
9
N02BE01
ATC
paracetamol; systemic, rectal
2.5
17.9
582
4802
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
68.5
17.8
20
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
17.8
17
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
17.8
17
*
C49.49
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the abdomen other or unspecified tumor
+∞
17.8
17
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
184.5
17.6
18
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
17.4
146
650
Y77
ICPC
Malignant neoplasm prostate
43.2
17.4
21
5
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.8
16.8
74
212
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
16.7
16
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
16.7
16
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
16.7
16
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
16.7
16
*
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
16.8
16.7
26
16
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.4
16.6
34
38
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
30.9
16.2
21
7
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
15.7
15
*
9591/3-C17.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of small intestine, NOS
+∞
15.7
15
*
8246/3-C17.2
ICD-O-3
Neuroendocrine carcinoma, NOS, of ileum
+∞
15.7
15
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
15.7
15
*
6402
FHL
Small bowel resection
87.1
15.6
17
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
163.5
15.5
16
*
JN4DD
NOMESCO Finland
Scout CT scan of torso
163.5
15.5
16
*
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
10.8
15.3
29
28
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
15.1
131
591
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
14.6
14
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
14.6
14
*
A04AD12
ATC
aprepitant; systemic
+∞
14.6
14
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
14.6
14
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
14.6
14
*
C26.9
ICD-10 Finland
Malignant neoplasm: Ill-defined sites within the digestive system
+∞
14.6
14
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
14.6
14
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
14.5
127
577
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
27.8
14.3
19
7
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
14.2
270
1717
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.6
14.2
49
112
D75
ICPC
Malignant neoplasm colon/rectum
43.4
14.2
17
*
HA1AA
NOMESCO Finland
X-ray mammography
6.0
13.9
38
66
K92.1
ICD-10 Finland
Melaena
3.8
13.9
61
174
ZX112
NOMESCO Finland
Subcutaneous
11.7
13.9
25
22
JN6AD
NOMESCO Finland
CT of torso and neck
54.5
13.9
16
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
5.5
13.8
41
79
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
13.8
90
341
C17
ICD-10 Finland
Malignant neoplasm of small intestine
+∞
13.6
13
*
8140/3-C17.2
ICD-O-3
Adenocarcinoma, NOS, of ileum
+∞
13.6
13
*
197
Kela drug reimbursment
Sunitinib
+∞
13.6
13
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
13.6
13
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
13.6
13
*
316
Kela drug reimbursment
Imatinib
+∞
13.6
13
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
13.6
13
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
13.6
13
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.9
13.6
44
94
R11
ICD-10 Finland
Nausea and vomiting
3.3
13.6
70
228
NK6AN
NOMESCO Finland
Total body bone isotope imaging
34.8
13.5
17
5
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.6
13.4
34
54
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
10.0
13.3
26
27
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
15.4
13.2
21
14
SPAT1153
SPAT
Removal of sutures
1.9
13.1
232
1429
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
51.0
12.9
15
*
K56.0
ICD-10 Finland
Paralytic ileus
9.9
12.8
25
26
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.3
12.6
38
75
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
32.7
12.6
16
5
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
12.5
12
*
XX9AD
NOMESCO Finland
Complementary CT
+∞
12.5
12
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
12.5
12
*
C26.0
ICD-10 Finland
Malignant neoplasm: Intestinal tract, part unspecified
+∞
12.5
12
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
12.5
12
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
12.5
12
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
12.5
12
*
ZXE00
NOMESCO Finland
One hour or less
1.9
12.2
259
1690
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.3
12.2
45
110
WX600
NOMESCO Finland
Single shot through catheter
16.2
12.2
19
12
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
11.9
94
401
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
30.6
11.7
15
5
R10.0
ICD-10 Finland
Acute abdomen
5.3
11.7
35
69
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
66.1
11.6
13
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
11.5
75
286
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
13.9
11.5
19
14
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
11.5
11
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
11.5
11
*
L01XE04
ATC
[U] sunitinib; oral
+∞
11.5
11
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
11.5
11
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
11.5
11
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
11.5
11
*
8140/3-C17.1
ICD-O-3
Adenocarcinoma, NOS, of jejunum
+∞
11.5
11
*
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
11.5
11
*
9680/3-C17.2
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of ileum
+∞
11.5
11
*
C18.09
ICD-10 Finland
Malignant tumor of caecum other or unspecified histology
+∞
11.5
11
*
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
+∞
11.5
11
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
11.5
11
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
11.5
11
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
11.5
11
*
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
121.9
11.5
12
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
9.8
11.3
22
23
A06AH03
ATC
naloxegol; oral
35.7
11.3
14
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
11.3
275
1868
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.6
11.3
50
145
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
20.4
11.2
16
8
Z51.88
ICD-10 Finland
Other specified medical care
6.3
11.2
29
48
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.9
11.1
45
121
ZX114
NOMESCO Finland
Intramuscular
10.3
11.1
21
21
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
44.0
10.9
13
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.2
10.9
58
194
M04AA01
ATC
allopurinol; systemic
2.2
10.8
117
584
KCD02
NOMESCO Finland
Transurethral resection of bladder
21.9
10.7
15
7
JEA00
NOMESCO Finland
Appendectomy
3.4
10.7
52
163
JDE00
NOMESCO Finland
Gastrojejunostomy
60.9
10.6
12
*
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
6.7
10.6
26
40
UJF02
NOMESCO Finland
Peroral enteroscopy
14.5
10.5
17
12
JJA20
NOMESCO Finland
Open biopsy of liver
111.6
10.4
11
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
111.6
10.4
11
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
10.4
10
*
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
+∞
10.4
10
*
9680/3-C17.0
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of duodenum
+∞
10.4
10
*
L02BB03
ATC
bicalutamide; oral
+∞
10.4
10
*
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
+∞
10.4
10
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
10.4
10
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
10.4
10
*
1522B
ICD-9 Finland
Malignant neoplasm of small intestine, including duodenum, Ileum[NEOPLASMA MALIGNUM ILEI,ALIA DEFINITA SEU NUD]
+∞
10.4
10
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
10.4
10
*
8140/3-C18.2
ICD-O-3
Adenocarcinoma, NOS, of ascending colon
+∞
10.4
10
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
10.4
10
*
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
+∞
10.4
10
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
10.4
10
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
10.4
10
*
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
10.4
10
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
10.4
10
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
10.4
10
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
10.4
284
1988
R4110
NOMESCO Finland
Physiotherapy
1.9
10.4
183
1111
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
10.8
10.3
19
18
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.1
10.3
55
185
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
10.2
39
100
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
10.2
142
789
WX704
NOMESCO Finland
Intubation
3.1
10.0
56
192
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
40.7
10.0
12
*
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
55.8
9.7
11
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
55.8
9.7
11
*
K65.0
ICD-10 Finland
Acute peritonitis
8.5
9.6
20
24
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.3
9.6
22
31
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
7.3
9.6
22
31
L02BA01
ATC
tamoxifen; oral
101.3
9.4
10
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
9.4
120
640
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
30.5
9.4
12
*
L01CB01
ATC
etoposide; systemic
+∞
9.4
9
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
9.4
9
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
9.4
9
*
176
Kela drug reimbursment
Regorafenib
+∞
9.4
9
*
8936/3-C17.1
ICD-O-3
Gastrointestinal stromal tumor of jejunum
+∞
9.4
9
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
22.0
9.4
13
6
B01AB04
ATC
dalteparin; parenteral
3.4
9.4
45
140
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.6
9.3
26
48
A06AD11
ATC
lactulose; oral
2.1
9.1
110
574
N02AX02
ATC
tramadol; systemic, rectal
1.7
9.0
286
2066
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
8.9
45
146
B81
ICPC
Anaemia vit B12/folate deficiency
3.7
8.9
38
108
Z2221
NOMESCO Finland
Medical doctor
1.8
8.8
175
1094
107
Kela drug reimbursment
Pernicious anaemia
5.5
8.8
25
47
J01MA12
ATC
levofloxacin; systemic
1.9
8.8
130
737
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.2
8.7
45
148
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
14.3
8.7
14
10
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
16.5
8.6
13
8
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.8
8.6
35
96
JFC00
NOMESCO Finland
Entero-enterostomy
91.1
8.4
9
*
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
91.1
8.4
9
*
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
91.1
8.4
9
*
C26.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of digestive system
+∞
8.3
8
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
8.3
8
*
8240/3-C17.1
ICD-O-3
Neuroendocrine tumor, NOS, of jejunum
+∞
8.3
8
*
C84.49
ICD-10 Finland
Peripheral T-cell lymphoma, unspecified cell type
+∞
8.3
8
*
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
+∞
8.3
8
*
9717/3-C17.9
ICD-O-3
Intestinal T-cell lymphoma of small intestine, NOS
+∞
8.3
8
*
C77.9
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph node, unspecified
+∞
8.3
8
*
369
Kela drug reimbursment
Regorafenib
+∞
8.3
8
*
JN5SR
NOMESCO Finland
Very extensive PET-CT of receptors in upper body
+∞
8.3
8
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
+∞
8.3
8
*
127
Kela drug reimbursment
Transplant complication
8.7
8.3
17
20
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.3
8.3
40
126
K50.9
ICD-10 Finland
Crohn disease, unspecified
6.9
8.1
19
28
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
22.3
8.0
11
5
1XC02
NOMESCO Finland
NA
22.3
8.0
11
5
WX892
NOMESCO Finland
Monitored bed care
2.6
8.0
60
248
K50.0
ICD-10 Finland
Crohn disease of small intestine
6.5
7.8
19
30
K90.0
ICD-10 Finland
Coeliac disease
3.9
7.7
30
79
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
45.5
7.7
9
*
JFF10
NOMESCO Finland
Loop enterostomy
45.5
7.7
9
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
7.7
241
1712
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
12.0
7.6
13
11
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
5.5
7.6
21
39
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.0
7.5
43
151
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.6
7.5
32
92
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
80.9
7.4
8
*
S55
ICPC
Skin, Local injection/infiltration
80.9
7.4
8
*
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
7.8
7.4
16
21
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
11.0
7.3
13
12
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
7.3
7
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
7.3
7
*
C17.3
ICD-10 Finland
Malignant neoplasm: Meckel diverticulum
+∞
7.3
7
*
E340, C179
ICD-10 Finland
NA
+∞
7.3
7
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
7.3
7
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.3
7
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
7.3
7
*
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
+∞
7.3
7
*
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
7.3
7
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
8130/2-C67.9
ICD-O-3
Papillary urothelial carcinoma, non-invasive of bladder, NOS
+∞
7.3
7
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
5.9
7.3
19
33
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.9
7.2
42
151
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
20.3
7.1
10
5
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
20.3
7.1
10
5
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
8.0
7.1
15
19
3AC01
NOMESCO Finland
NA
7.1
7.0
16
23
J01DB01
ATC
cefalexin; oral
1.6
6.9
509
4417
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.6
6.9
15
20
Z3226
NOMESCO Finland
Physiotherapist
1.8
6.9
120
713
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
8.4
6.8
14
17
A55
ICPC
General and Unspecified, Local injection/infiltration
8.4
6.8
14
17
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
6.8
152
980
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
40.4
6.8
8
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
40.4
6.8
8
*
JAK03
NOMESCO Finland
Laparotomy and peritoneal irrigation
40.4
6.8
8
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
40.4
6.8
8
*
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
3.0
6.8
36
123
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
22.8
6.7
9
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
22.8
6.7
9
*
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
7.9
6.6
14
18
S18
ICPC
Laceration/cut
1.5
6.6
264
1979
JAL30
NOMESCO Finland
Omentectomy
12.4
6.6
11
9
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.9
6.6
20
42
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
70.4
6.4
7
*
JFB43
NOMESCO Finland
Left hemicolectomy
14.5
6.4
10
7
JAL00
NOMESCO Finland
Biopsy of peritoneum
14.5
6.4
10
7
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
14.5
6.4
10
7
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.6
6.4
15
23
Z3231
NOMESCO Finland
Registered nurse
1.6
6.4
169
1142
B80
ICPC
Iron deficiency anaemia
4.6
6.3
20
44
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
6.3
27
79
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
18.2
6.3
9
5
JF1AD
NOMESCO Finland
Small bowel CT
18.2
6.3
9
5
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
18.2
6.3
9
5
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
6.3
6
*
8140/3-C18.0
ICD-O-3
Adenocarcinoma, NOS, of cecum
+∞
6.3
6
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
6.3
6
*
C84.5
ICD-10 Finland
Other mature T/NK-cell lymphomas
+∞
6.3
6
*
L01XE21
ATC
[U] regorafenib; oral
+∞
6.3
6
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
6.3
6
*
C18.29
ICD-10 Finland
Malignant tumor of the ascending colon or other unspecified histology
+∞
6.3
6
*
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
+∞
6.3
6
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
+∞
6.3
6
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
6.3
6
*
9691/3-C17.9
ICD-O-3
Follicular lymphoma, grade 2 of small intestine, NOS
+∞
6.3
6
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
6.3
6
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
6.3
6
*
C24.1
ICD-10 Finland
Malignant neoplasm: Ampulla of Vater
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
6.2
138
885
D99
ICPC
Disease digestive system other
7.1
6.2
14
20
6101
FHL
Exploratory laparotomy, includes possible biopases
26.9
6.2
8
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
26.9
6.2
8
*
-50
ICPC
Medication/prescr/renewal
2.9
6.2
36
129
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
6.1
83
453
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
4.1
6.1
22
55
C03CA01
ATC
furosemide; systemic
1.6
6.1
209
1504
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.1
196
1387
WX110
NOMESCO Finland
Local anesthesy
1.5
6.1
387
3193
TQW99
NOMESCO Finland
Other minor procedure on skin
3.3
6.1
28
87
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.9
6.0
35
126
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.9
6.0
23
61
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
6.0
52
235
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
6.0
72
375

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_SMALL_INTESTINE_EXALLC – Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

GWS hits: 4

This endpoint is excluded (different definition than used in FinnGen).