info icon

This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Thymus

CD2_BENIGN_THYMUS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D15.0&
  • Hospital discharge: ICD-9 2126
  • Cause of death: ICD-10 D15.0&
  • Cause of death: ICD-9 2126

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D15
Name in latin
Neoplasma benignum thymi

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 76 39 37
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 61.70 58.78 64.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
62
Matched controls
621
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
+∞
83.7
60
*
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
+∞
27.1
24
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
+∞
25.8
23
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
17.9
17.1
28
27
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
15.2
14
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
+∞
14.1
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.7
12.2
47
179
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
14.9
9.8
16
14
G70.0
ICD-10 Finland
Myasthenia gravis
+∞
9.6
9
*
8582/3-C37.9
ICD-O-3
Thymoma, type AB of thymus
+∞
9.6
9
*
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
9.6
9
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
9.6
9
*
N07AA02
ATC
pyridostigmine; systemic
103.6
8.6
9
*
ZXC96
NOMESCO Finland
Robot assisted procedure
103.6
8.6
9
*
108
Kela drug reimbursment
Myasthenia gravis
+∞
8.5
8
*
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
8.5
8
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.9
8.1
25
63
D15.2
ICD-10 Finland
Benign neoplasm: Mediastinum
+∞
7.4
7
*
R4110
NOMESCO Finland
Physiotherapy
5.0
7.4
28
88
WX408
NOMESCO Finland
General anesthesy, balanced
4.8
7.4
29
95
GD1AD
NOMESCO Finland
Thorax CT examination
19.5
7.0
10
6
WZC30
NOMESCO Finland
Teaching
6.9
6.8
17
32
B01AB05
ATC
enoxaparin; parenteral
4.5
6.8
28
95

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
16
24.18
32.14
1.3
1.3
—
—
—
0
0
61
249
8.35
15.08
4.8
7.9
1.1
1.3
inr
—
8
65
20
30
8.69
13.49
8.8
7.1
—
—
—
0
0
20
36
7.18
11.39
15.3
9.0
0.6
0.8
%
0.75
20
36
45
171
5.00
11.08
2.6
2.0
—
—
—
0
0
46
187
4.70
10.17
8.2
4.6
—
—
—
0
0
19
37
6.51
9.96
15.9
8.8
1.2
1.6
%
0.62
19
37
44
189
4.15
8.67
2.3
1.5
—
—
—
0
0
21
51
5.31
8.66
11.8
9.5
—
—
—
0
0
61
335
5.16
8.45
14.1
6.3
4.1
4.2
e9/l
0.14
52
284
57
300
4.60
8.30
7.9
4.8
0.6
0.5
e9/l
1.32
46
253
52
268
3.98
7.54
9.1
5.1
9.4
8.3
%
1.49
52
255
50
253
3.85
7.41
9.1
4.9
0.7
0.7
%
0.28
50
238
56
306
4.15
7.38
8.1
5.0
1.6
1.8
e9/l
0.65
47
265
55
300
4.02
7.20
8.1
4.9
0.0
0.0
e9/l
0.24
46
252
56
310
4.06
7.15
10.1
5.2
0.2
0.2
e9/l
1.06
47
269
23
72
4.15
6.83
15.3
6.3
104.2
103.8
mmol/l
0.12
23
72
51
273
3.64
6.69
8.7
4.9
61.1
57.7
%
1.38
51
256
42
202
3.41
6.50
4.3
3.2
18.6
80.5
e6/l
1.27
30
140
35
151
3.44
6.44
3.7
2.9
0.2
0.6
e6/l
1.63
27
110
37
170
3.29
6.08
3.9
2.9
21.2
433.0
e6/l
0.54
28
128
16
41
4.68
6.07
10.3
4.0
—
—
—
0
0
33
144
3.28
5.87
3.8
2.7
—
—
—
0
0
35
160
3.20
5.74
4.5
4.0
—
—
—
0
0
63
410
4.14
5.66
4.9
3.8
—
—
—
0
0
16
45
4.24
5.38
1.4
1.4
—
—
—
0
0
13
35
4.27
4.59
7.8
7.2
26.0
25.3
mmol/l
0.36
13
35
30
145
2.77
4.23
9.5
4.1
—
—
—
0
0
8
10
8.78
4.17
2.4
3.4
—
—
—
0
0
19
73
3.14
4.01
1.2
1.2
453.3
521.8
titre
—
6
22
43
259
2.52
3.78
12.3
7.2
0.0
0.0
e9/l
0.48
33
203
20
83
2.91
3.68
2.0
1.7
—
—
—
0
0
32
172
2.49
3.55
3.0
2.8
—
—
—
0
0
17
66
3.03
3.50
5.8
4.7
—
—
—
0
0
35
201
2.37
3.31
2.5
2.1
161.5
170.7
u/l
0.08
35
188
15
56
3.09
3.29
2.2
1.5
65.9
66.9
g/l
0.21
15
51
18
77
2.75
3.11
1.7
1.5
—
—
—
0
0
9
21
4.71
3.10
4.9
4.3
—
—
—
0
0
19
84
2.68
3.08
2.3
2.7
12.3
14.4
umol/l
0.57
19
78
5
5
10.57
3.02
1.0
1.8
4.7
2.9
u/ml
—
5
5
13
47
3.13
2.99
1.3
1.1
—
—
—
0
0
38
234
2.25
2.98
1.7
1.8
91.1
92.9
pmol/l
0.12
29
112
14
56
2.84
2.71
1.4
1.6
—
—
—
0
0
15
63
2.72
2.66
1.3
1.4
—
—
—
0
0
17
80
2.45
2.41
1.7
1.9
—
—
—
0
0
10
35
3.14
2.41
1.0
1.5
—
—
—
0
0
24
132
2.20
2.40
3.0
3.5
25.3
197.5
ng/l
2.00
19
109
43
303
1.97
2.16
4.8
4.8
0.0
0.0
estimate
—
8
42
5
10
5.26
2.10
1.0
2.1
—
—
—
0
0
8
26
3.31
2.08
1.0
1.2
—
—
—
0
0
43
308
1.91
2.01
3.5
3.6
0.0
0.0
estimate
—
7
40
6
16
3.98
1.97
2.7
1.8
—
—
—
0
0
5
11
4.78
1.97
1.2
1.0
—
—
—
0
0
15
73
2.31
1.97
2.1
1.9
—
—
—
0
0
35
237
1.88
1.92
3.7
3.7
—
—
—
0
0
22
127
2.03
1.91
1.3
1.2
—
—
—
0
0
15
74
2.28
1.91
5.6
1.9
2.1
1.5
%
1.94
15
67
21
121
2.02
1.82
1.3
1.2
2.1
2.5
g/l
0.47
15
64
41
297
1.83
1.78
3.5
3.6
0.0
0.0
estimate
—
7
45
56
449
1.94
1.74
3.9
3.8
—
—
—
0
0
6
19
3.34
1.69
23.3
3.2
3.6
4.1
mmol/l
—
6
19
24
149
1.89
1.68
3.4
3.6
—
—
—
0
0
12
57
2.31
1.65
3.4
2.0
79.3
61.5
e9/l
—
7
43
6
20
3.16
1.61
6.2
4.5
24.2
24.6
mmol/l
—
6
20
28
185
1.81
1.61
3.5
3.4
69.8
54.5
mg/l
0.14
21
120
22
136
1.87
1.55
1.6
1.4
18.1
20.9
nmol/l
0.55
22
114
62
523
2.01
1.54
31.3
14.2
14.3
13.6
%
1.68
62
514
11
52
2.30
1.53
1.4
1.2
—
—
—
0
0
7
28
2.65
1.49
2.3
2.5
—
—
—
0
0
10
47
2.30
1.41
2.8
1.3
—
—
—
0
0
20
124
1.83
1.39
3.5
2.2
2.5
2.4
mmol/l
0.45
15
109
16
92
1.94
1.38
1.3
1.2
—
—
—
0
0
13
70
2.03
1.34
2.5
1.8
92.6
99.4
ug/g
0.07
13
54
8
40
2.12
1.16
7.9
2.8
4.1
3.7
e9/l
—
8
29
11
59
2.01
1.14
1.5
1.4
—
—
—
0
0
7
31
2.38
1.14
1.1
1.3
—
—
—
0
0
7
33
2.23
1.09
7.6
2.5
1.2
1.3
%
—
7
33
10
53
2.02
1.07
5.4
4.5
—
—
—
0
0
29
215
1.56
1.02
2.5
2.2
61.5
57.8
u/l
0.27
29
198
27
198
1.56
1.00
4.1
4.2
13.0
7.6
mg/mmol
0.29
20
129
6
27
2.32
0.96
1.0
1.1
—
—
—
0
0
6
27
2.32
0.96
30.7
2.9
—
—
—
0
0
9
54
1.75
0.78
8.9
4.7
64.0
98.3
ng/l
—
9
48
32
255
1.44
0.77
5.2
3.8
40.3
51.9
ng/l
0.25
26
184
5
26
1.99
0.72
3.2
3.9
—
—
—
0
0
62
564
1.54
0.69
30.6
13.2
39.0
40.9
%
1.02
46
401
7
43
1.69
0.69
1.0
1.3
—
—
—
0
0
24
185
1.43
0.68
4.9
3.8
—
—
—
0
0
15
110
1.45
0.54
1.1
1.3
1.2
11.7
u/ml
—
5
54
6
40
1.54
0.53
2.3
1.6
—
—
—
0
0
17
217
0.72
0.51
3.8
3.2
—
—
—
0
0
8
55
1.51
0.45
1.6
1.5
—
—
—
0
0
8
58
1.42
0.43
1.5
1.4
—
—
—
0
0
15
115
1.38
0.43
1.9
1.9
460.3
485.3
pmol/l
0.17
15
103
8
60
1.37
0.42
6.4
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
5
36
1.42
0.39
1.0
1.3
—
98.5
—
0
15
19
154
1.31
0.39
3.2
3.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
8
69
1.18
0.17
1.3
3.0
31.8
7.3
ug/l
—
8
58
50
481
1.12
0.12
3.9
3.7
15.0
15.0
pmol/l
0.04
43
434
13
115
1.16
0.11
2.1
1.7
978.3
1240.4
nmol/l
0.58
13
91
18
166
1.11
0.08
4.9
3.9
0.0
0.0
estimate
—
7
44
15
140
1.09
0.05
1.1
1.3
0.8
1.0
u/ml
—
5
41
10
92
1.10
0.03
61.5
20.2
—
1.4
—
0
15
18
188
0.94
0.02
1.3
1.7
1.4
1.4
mmol/l
0.03
18
160
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
0.00
7.8
4.7
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
22.6
—
0
6
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
23
230
1.00
0.00
5.7
3.6
3.9
1.9
ug/l
0.84
23
210
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
12.3
—
0
5
0
5
0.00
0.00
0.0
1.6
—
8.6
—
0
5
0
6
0.00
0.00
0.0
1.0
—
32.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_THYMUS_EXALLC – Benign neoplasm: Thymus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).