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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Vertebral column

CD2_BENIGN_VERTEB_COLUMN_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.6&
  • Hospital discharge: ICD-9 2132
  • Hospital discharge: ICD-8 21301
  • Cause of death: ICD-10 D16.6&
  • Cause of death: ICD-9 2132
  • Cause of death: ICD-8 21301

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum columnae vertebralis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 88 46 42
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 52.69 49.76 55.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
75
Matched controls
750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
+∞
71.8
57
*
21301
ICD-8 Finland
Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)
+∞
14.0
13
*
H02AB02
ATC
dexamethasone; systemic
75.9
6.5
7
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
6.3
6
*
2132A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx
+∞
6.3
6
*
JN4BD
NOMESCO Finland
Extensive body CT
8.0
6.0
13
19

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
43
4.00
4.86
5.3
3.1
—
—
—
0
0
41
217
2.67
4.79
2.6
1.6
—
—
—
0
0
10
21
5.24
4.66
1.6
1.3
—
—
—
0
0
48
304
2.27
3.50
6.6
4.8
0.0
0.0
estimate
—
8
48
28
146
2.35
3.17
6.1
3.1
—
—
—
0
0
47
305
2.16
3.12
5.6
3.3
0.0
0.0
estimate
—
9
48
12
41
3.23
2.99
1.1
1.1
—
—
—
0
0
47
313
2.08
2.84
5.5
3.3
0.0
0.0
estimate
—
9
46
28
156
2.17
2.67
7.1
3.4
0.0
0.0
estimate
—
9
47
62
466
2.12
2.61
4.0
3.6
—
—
—
0
0
38
243
1.99
2.49
5.8
3.2
—
—
—
0
0
24
129
2.18
2.48
11.1
5.2
—
—
—
0
0
19
94
2.30
2.38
1.3
1.1
—
—
—
0
0
5
10
5.22
2.10
2.6
1.3
—
—
—
0
0
23
131
2.02
2.03
4.7
2.3
0.8
0.8
ug/l
0.13
18
92
17
88
2.15
1.91
1.2
2.2
177.0
89.2
ug/g
—
10
71
37
252
1.81
1.90
8.8
8.1
1.3
1.2
inr
—
7
62
58
452
1.83
1.90
4.8
3.8
—
—
—
0
0
27
168
1.88
1.84
2.7
2.7
0.2
0.3
e6/l
0.37
22
112
7
23
3.21
1.84
5.9
4.1
—
—
—
0
0
26
162
1.86
1.76
2.6
2.6
—
—
—
0
0
73
630
1.93
1.51
15.9
12.8
41.1
40.5
%
0.50
53
475
10
47
2.27
1.39
3.2
2.1
0.2
0.2
g/l
—
10
40
26
173
1.71
1.39
5.3
2.9
—
—
—
0
0
47
366
1.61
1.37
10.5
6.1
4.5
4.2
e9/l
0.30
42
310
52
416
1.61
1.35
6.2
3.6
—
6939.6
—
0
8
8
34
2.48
1.33
5.9
12.9
0.7
0.6
%
—
8
34
8
34
2.48
1.33
5.9
13.0
1.1
1.7
%
—
8
34
35
255
1.62
1.33
10.0
7.7
0.0
0.0
e9/l
0.49
28
193
23
150
1.72
1.32
4.3
3.9
—
—
—
0
0
5
18
2.88
1.30
1.6
1.1
—
—
—
0
0
15
86
1.90
1.29
2.5
1.8
—
—
—
0
0
8
38
2.21
1.22
5.8
3.7
—
—
—
0
0
80
730
2.05
1.17
15.4
10.6
—
—
—
0
0
9
49
1.93
1.02
5.0
1.3
64.9
68.1
g/l
—
9
44
35
269
1.50
1.01
2.0
2.0
99.8
98.2
pmol/l
0.08
22
136
9
50
1.89
1.00
10.4
12.0
—
—
—
0
0
20
138
1.58
0.92
7.6
5.1
—
—
—
0
0
29
218
1.49
0.92
3.3
3.2
12.9
104.3
e6/l
1.14
21
147
8
45
1.85
0.87
1.8
1.4
—
—
—
0
0
6
32
1.94
0.83
6.8
8.8
27.3
25.5
mmol/l
—
6
32
42
345
1.42
0.83
6.6
5.1
0.2
0.2
e9/l
1.63
37
301
25
187
1.47
0.80
2.6
2.6
82.1
54.8
e6/l
0.14
19
135
20
143
1.52
0.79
1.3
1.3
1.0
1.3
u/ml
—
5
43
6
34
1.82
0.78
5.2
2.5
1.0
1.4
%
—
6
34
13
84
1.64
0.77
2.0
2.7
—
—
—
0
0
7
38
1.91
0.75
3.4
17.2
—
—
—
0
0
41
340
1.39
0.75
6.5
5.2
1.8
1.8
e9/l
0.12
34
301
5
26
1.98
0.72
6.4
34.0
—
—
—
0
0
18
129
1.50
0.70
1.7
1.3
2.4
2.8
g/l
0.29
13
77
27
211
1.40
0.68
5.9
5.1
—
—
—
0
0
7
43
1.68
0.68
1.9
1.3
—
—
—
0
0
10
62
1.69
0.68
1.8
1.7
365.7
426.5
nmol/l
—
10
54
77
719
1.57
0.65
5.2
5.0
2.8
2.7
mmol/l
0.12
71
675
0
21
0.00
0.61
0.0
1.2
—
—
—
0
0
23
179
1.39
0.59
3.8
2.1
—
—
—
0
0
13
90
1.52
0.59
8.8
2.9
0.8
0.8
mmol/l
0.38
13
82
21
161
1.40
0.59
3.9
3.4
—
—
—
0
0
39
331
1.32
0.58
6.6
5.0
0.5
0.6
e9/l
1.29
34
283
75
701
1.47
0.57
4.3
4.5
1.5
1.5
mmol/l
0.07
69
655
63
573
1.35
0.57
19.8
13.1
13.6
13.7
%
0.09
63
560
9
61
1.53
0.56
1.4
1.3
—
—
—
0
0
35
298
1.29
0.50
4.5
2.6
120.9
110.3
ug/l
0.12
35
271
26
214
1.31
0.47
2.3
2.0
208.2
158.8
u/l
0.25
26
201
75
709
1.39
0.45
16.3
11.2
19.1
22.1
mg/l
0.43
62
540
5
32
1.60
0.43
1.8
1.7
—
—
—
0
0
38
332
1.25
0.43
6.8
5.0
0.0
0.0
e9/l
0.39
33
288
5
33
1.55
0.42
4.2
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
5.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
4.1
—
26.7
—
0
11
74
706
1.30
0.33
5.0
4.5
4.6
4.6
mmol/l
0.09
69
665
71
676
1.26
0.31
4.4
4.1
1.1
1.3
mmol/l
1.82
66
628
8
66
1.23
0.27
2.6
2.1
3.4
6.1
ug/l
—
8
57
9
73
1.26
0.26
7.9
4.4
2.8
1.7
mmol/l
—
9
58
72
691
1.23
0.25
4.4
4.3
5.7
6.0
mmol/l
1.00
67
638
0
11
0.00
0.21
0.0
3.2
—
58.2
—
0
11
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
7
57
1.25
0.19
1.1
1.2
—
—
—
0
0
17
148
1.18
0.18
3.1
1.7
8.5
0.9
mg/l
0.60
11
113
5
67
0.73
0.17
1.8
1.8
—
—
—
0
0
10
83
1.23
0.16
3.5
1.8
—
—
—
0
0
18
161
1.15
0.14
3.3
1.9
2.8
2.8
mg/l
0.02
18
139
10
85
1.20
0.13
1.5
1.5
—
—
—
0
0
10
116
0.84
0.12
1.8
1.7
—
—
—
0
0
31
291
1.10
0.11
4.2
3.5
47.5
51.8
ng/l
0.06
21
193
5
44
1.14
0.10
1.4
1.4
—
—
—
0
0
17
155
1.12
0.10
1.3
1.3
—
—
—
0
0
11
97
1.15
0.09
2.6
2.8
13.3
13.4
umol/l
0.02
11
88
6
71
0.83
0.08
1.5
1.3
—
—
—
0
0
8
75
1.07
0.07
1.5
1.5
—
—
—
0
0
8
76
1.06
0.07
1.6
1.3
—
—
—
0
0
7
84
0.82
0.07
1.3
1.3
—
—
—
0
0
21
220
0.94
0.04
3.6
4.0
5.8
8.9
mg/mmol
0.41
14
148
20
208
0.95
0.02
3.1
3.4
27.1
355.5
mg/l
0.60
12
143
24
246
0.97
0.00
3.3
3.2
—
—
—
0
0
18
179
1.01
0.00
4.5
4.0
—
—
—
0
0
8
80
1.00
0.00
8.0
4.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
249.9
—
0
9
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
9
90
1.00
0.00
17.6
15.2
—
1.1
—
0
18
5
49
1.02
0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
22.2
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.8
—
1234.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
123.3
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
4.2
—
0
6
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
10.1
—
0.7
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.8
—
695.6
—
0
5
5
58
0.85
0.00
3.6
1.6
48.4
64.0
e9/l
—
5
43
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
13.2
—
0
5
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
0.2
—
0
5
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_VERTEB_COLUMN_EXALLC – Benign neoplasm: Vertebral column

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).