Benign neoplasm: Vertebral column

CD2_BENIGN_VERTEB_COLUMN_EXALLC

No definition available.

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.6& Hospital discharge: ICD-9 — 2132 Hospital discharge: ICD-8 — 21301 Cause of death: ICD-10 — D16.6& Cause of death: ICD-9 — 2132 Cause of death: ICD-8 — 21301 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum columnae vertebralis

NAME	CD2_BENIGN_VERTEB_COLUMN_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D166
HD_ICD_9	2132
HD_ICD_8	21301
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D166
COD_ICD_9	2132
COD_ICD_8	21301
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Benign neoplasm: Vertebral column based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Vertebral column

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	88	46	42
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	52.69	49.76	55.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
75: Matched controls
750

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.6

ICD-10 Finland

Benign neoplasm: Vertebral column

+∞

71.8

21301

ICD-8 Finland

Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)

+∞

14.0

H02AB02

ATC

dexamethasone; systemic

75.9

6.5

NK6CT

NOMESCO Finland

Bone biopsy with CT guidance

+∞

6.3

2132A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx

+∞

6.3

JN4BD

NOMESCO Finland

Extensive body CT

8.0

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40761535) Cells panel - Urine sediment

4.00

4.86

5.3

3.1

—

(40768804) Tissue Pathology biopsy report

217

2.67

4.79

2.6

1.6

—

(4035726)

5.24

4.66

1.6

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

304

2.27

3.50

6.6

4.8

0.00

estimate

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

288

2.25

3.43

5.8

8.2

1.20

1.22

mmol/l

0.76

248

(3011397) Hemoglobin [Presence] in Urine by Test strip

146

2.35

3.17

6.1

3.1

—

(3035350) Ketones [Presence] in Urine by Test strip

305

2.16

3.12

5.6

3.3

0.00

estimate

—

(3002256) Pathology report gross observation

3.23

2.99

1.1

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

2.95

2.96

2.6

1.7

60.00

64.89

ml/min/173m2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.69

2.94

1.5

—

(3009261) Glucose [Presence] in Urine by Test strip

313

2.08

2.84

5.5

3.3

0.00

estimate

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.61

2.79

1.5

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.57

2.72

6.6

7.8

—

(3029937) Albumin [Presence] in Urine by Test strip

156

2.17

2.67

7.1

3.4

0.00

estimate

—

(3044889) 12 lead EKG panel

466

2.12

2.61

4.0

3.6

—

(3015736) pH of Urine

243

1.99

2.49

5.8

3.2

—

(40758558) Short blood count panel - Blood

129

2.18

2.48

11.1

5.2

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

6.54

2.40

1.4

1.0

—

(40768797) Stomach Pathology biopsy report

2.30

2.38

1.3

1.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

235

1.90

2.17

6.4

3.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

5.22

2.10

2.6

1.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

131

2.02

2.03

4.7

2.3

0.84

0.79

ug/l

0.13

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

4.75

1.97

1.4

1.1

—

(3048689) Calprotectin [Mass/mass] in Stool

2.15

1.91

1.2

2.2

176.97

89.17

ug/g

—

(3032080) INR in Blood by Coagulation assay

252

1.81

1.90

8.8

8.1

1.27

1.23

inr

—

(3037467) Urinalysis macro (dipstick) panel - Urine

452

1.83

1.90

4.8

3.8

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

209

1.83

1.88

3.6

2.9

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.35

1.85

1.4

—

(3030467) Casts [#/volume] in Urine by Automated count

168

1.88

1.84

2.7

0.20

0.32

e6/l

0.37

112

(3020891) Body temperature

3.21

1.84

5.9

4.1

—

(36304419) Bacteria [Presence] in Urine

162

1.86

1.76

2.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

630

1.93

1.51

15.9

12.8

41.11

40.45

0.50

475

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

178

1.75

1.50

6.1

3.6

22.36

24.10

0.18

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.45

1.48

2.2

1.6

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

2.27

1.39

3.2

2.1

0.19

0.22

g/l

—

(3026008) Bacteria identified in Urine by Culture

173

1.71

1.39

5.3

2.9

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

115

1.83

1.39

2.5

2.4

2.25

0.85

e6/l

0.41

(3013650) Neutrophils [#/volume] in Blood by Automated count

366

1.61

1.37

10.5

6.1

4.47

4.20

e9/l

0.30

310

(3031040) Bacteria [#/volume] in Urine by Automated count

416

1.61

1.35

6.2

3.6

—

6939.63

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.48

1.33

5.9

12.9

0.74

0.65

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.48

1.33

5.9

13.0

1.14

1.66

—

(3021589) Normoblasts [#/volume] in Blood

255

1.62

1.33

10.0

7.7

0.00

e9/l

0.49

193

(3023368) Bacteria identified in Blood by Culture

150

1.72

1.32

4.3

3.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

101

1.85

1.31

1.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.88

1.30

1.6

1.1

—

(3000494) Fungus identified in Specimen by Culture

1.90

1.29

2.5

1.8

—

(40761536) Microorganisms panel - Urine sediment

2.21

1.22

5.8

3.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.15

1.19

2.0

1.5

—

(40761511) CBC panel - Blood by Automated count

730

2.05

1.17

15.4

10.6

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.93

1.02

5.0

1.3

64.86

68.06

g/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

269

1.50

1.01

2.0

99.75

98.22

pmol/l

0.08

136

(3000991) Gas panel - Venous blood

1.89

1.00

10.4

12.0

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.99

0.0

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

279

1.49

0.99

5.4

4.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

138

1.58

0.92

7.6

5.1

—

(3018095) Leukocytes [#/volume] in Urine

218

1.49

0.92

3.3

3.2

12.94

104.30

e6/l

1.14

147

(4010399)

1.85

0.87

1.8

1.4

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.94

0.83

6.8

8.8

27.25

25.54

mmol/l

—

(3013115) Eosinophils [#/volume] in Blood

345

1.42

0.83

6.6

5.1

0.16

0.19

e9/l

1.63

301

(3002582) Erythrocytes [#/volume] in Urine

187

1.47

0.80

2.6

82.15

54.75

e6/l

0.14

135

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

143

1.52

0.79

1.3

0.98

1.29

u/ml

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.79

0.0

1.6

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.82

0.78

5.2

2.5

1.03

1.36

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.24

0.77

1.4

1.6

—

(3042936) Bacteria identified in Isolate by Culture

1.64

0.77

2.0

2.7

—

(3019060) Gas panel - Arterial blood

1.91

0.75

3.4

17.2

—

(3019198) Lymphocytes [#/volume] in Blood

340

1.39

0.75

6.5

5.2

1.77

1.81

e9/l

0.12

301

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.98

0.72

6.4

34.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

129

1.50

0.70

1.7

1.3

2.42

2.77

g/l

0.29

(42870588) Differential panel, method unspecified - Blood

211

1.40

0.68

5.9

5.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.68

0.68

1.9

1.3

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.69

0.68

1.8

1.7

365.70

426.54

nmol/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

719

1.57

0.65

5.2

5.0

2.76

2.72

mmol/l

0.12

675

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.61

0.0

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

179

1.39

0.59

3.8

2.1

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.52

0.59

8.8

2.9

0.82

0.84

mmol/l

0.38

(3041096) Erythrocytes [Presence] in Urine by Automated

161

1.40

0.59

3.9

3.4

—

(3001604) Monocytes [#/volume] in Blood

331

1.32

0.58

6.6

5.0

0.50

0.57

e9/l

1.29

283

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

701

1.47

0.57

4.3

4.5

1.45

1.46

mmol/l

0.07

655

(3002385) Erythrocyte distribution width [Ratio]

573

1.35

0.57

19.8

13.1

13.62

13.67

0.09

560

(3022145) Colonoscopy Study observation

1.53

0.56

1.4

1.3

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

298

1.29

0.50

4.5

2.6

120.94

110.32

ug/l

0.12

271

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

214

1.31

0.47

2.3

2.0

208.23

158.82

u/l

0.25

201

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

709

1.39

0.45

16.3

11.2

19.14

22.08

mg/l

0.43

540

(3001019) Free T4 and TSH panel - Serum or Plasma

1.60

0.43

1.8

1.7

—

(3006315) Basophils [#/volume] in Blood

332

1.25

0.43

6.8

5.0

0.04

e9/l

0.39

288

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

522

1.26

0.42

8.4

5.1

71.13

75.29

u/l

0.39

470

(3000330) Specific gravity of Urine by Test strip

1.55

0.42

4.2

3.5

—

(3024928) Oxygen saturation in Venous blood

0.00

0.41

0.0

5.6

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.41

0.0

1.3

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.41

0.0

1.3

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.40

0.0

4.1

—

26.73

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

107

1.37

0.40

2.6

2.5

0.83

2.71

e6/l

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.64

0.34

1.3

2.3

1.15

1.46

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

653

1.26

0.34

13.0

10.5

84.05

81.14

ml/min/173m2

0.47

517

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

706

1.30

0.33

5.0

4.5

4.56

4.59

mmol/l

0.09

665

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

102

1.32

0.32

1.6

1.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

676

1.26

0.31

4.4

4.1

1.12

1.29

mmol/l

1.82

628

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.23

0.27

2.6

2.1

3.35

6.12

ug/l

—

(3002032) Base excess in Venous blood by calculation

1.26

0.26

7.9

4.4

2.77

1.70

mmol/l

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

691

1.23

0.25

4.4

4.3

5.74

6.00

mmol/l

1.00

638

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

457

1.16

0.24

2.8

3.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.20

0.22

1.0

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.21

0.0

3.2

—

58.23

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.3

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.21

0.0

1.6

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.21

0.0

1.3

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

4.50

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

137

1.21

0.20

3.9

2.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.20

0.0

1.1

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.20

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.20

0.0

1.2

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

3.1

—

(36660697) Celiac disease serology panel - Serum

1.25

0.19

1.1

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.22

0.19

3.9

3.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

148

1.18

0.18

3.1

1.7

8.49

0.85

mg/l

0.60

113

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.73

0.17

1.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.23

0.16

3.5

1.8

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

161

1.15

0.14

3.3

1.9

2.79

2.81

mg/l

0.02

139

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.20

0.13

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

116

0.84

0.12

1.8

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

291

1.10

0.11

4.2

3.5

47.49

51.82

ng/l

0.06

193

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.14

0.10

1.4

—

(3003694) ABO and Rh group [Type] in Blood

155

1.12

0.10

1.3

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.15

0.09

2.6

2.8

13.33

13.43

umol/l

0.02

(3000492) Spirometry study

0.83

0.08

1.5

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.07

0.07

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.06

0.07

1.6

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.85

0.07

1.7

2.0

—

(21494755) Public health laboratory ask at order entry panel

0.82

0.07

1.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

220

0.94

0.04

3.6

4.0

5.77

8.94

mg/mmol

0.41

148

(3012516) Albumin [Mass/volume] in Urine

208

0.95

0.02

3.1

3.4

27.13

355.48

mg/l

0.60

143

(1761868) Lipid panel - Serum or Plasma

246

0.97

0.00

3.3

3.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

128

1.02

0.00

1.5

—

(3013512) EKG study

179

1.01

0.00

4.5

4.0

—

(3012544) pH of Venous blood

1.00

0.00

8.0

4.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.98

0.00

1.4

1.8

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.5

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

2.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

249.89

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

2.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.7

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.5

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.00

0.00

17.6

15.2

—

1.09

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.02

0.00

1.4

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.7

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

22.20

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.7

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.4

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

6.8

—

1234.80

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.0

1.1

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

123.30

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3024263) Appearance of Synovial fluid

0.00

0.0

1.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

4.17

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.8

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.3

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

10.1

—

0.68

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.8

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

3.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

6.8

—

695.60

—

(3023520) Reticulocytes [#/volume] in Blood

0.85

0.00

3.6

1.6

48.36

64.00

e9/l

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.8

—

(3011648) Oxygen content in Venous blood

0.00

0.0

2.6

—

13.24

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

1.04

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.3

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.1

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3010503) CD19 cells [#/volume] in Blood

0.00

0.0

1.2

—

0.23

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

2.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

2.3

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.7

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.5

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_VERTEB_COLUMN_EXALLC – Benign neoplasm: Vertebral column

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Vertebral column

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints