Explosion of other materials

VWXY20_EXPLOSION_OTHER_MATERI

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — W40 Cause of death: ICD-10 — W40 2 out of 7 registries used, show all original rules.	120
4. Check minimum number of events None	120
5. Include endpoints None	120
6. Filter based on genotype QC (FinnGen only)	112

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 5
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: W[2-4]

NAME	VWXY20_EXPLOSION_OTHER_MATERI
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	W40
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	W40
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Explosion of other materials based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	112	22	90
Unadjusted period prevalence (%)	0.03	0.01	0.04
Median age at first event (years)	43.66	39.78	44.60

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
120: Matched controls
1200

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

W40

ICD-10 Finland

Explosion of other materials

+∞

155.4

113

T20.1

ICD-10 Finland

Burn of first degree of head and neck

85.1

7.5

T20.2

ICD-10 Finland

Burn of second degree of head and neck

73.6

6.5

A29

ICPC

General symptom/complaint other

3.7

6.4

X58

ICD-10 Finland

Exposure to other specified factors

3.2

6.1

110

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3044640) Blood type and Crossmatch panel - Blood

277

2.30

4.55

2.2

2.3

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

10.52

4.06

2.0

1.6

—

(3042936) Bacteria identified in Isolate by Culture

123

2.30

3.10

2.3

1.8

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

107

2.29

2.79

3.0

2.3

19.03

25.28

1.08

(3000991) Gas panel - Venous blood

2.44

2.58

7.7

7.6

—

(3011288) Drugs identified in Urine by Screen method

2.85

2.53

1.6

3.7

—

(3013512) EKG study

249

0.39

2.46

3.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

398

1.76

2.38

2.6

2.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.92

2.34

3.6

8.5

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

2.14

2.15

4.7

6.8

4.98

5.01

kpa

0.05

(3027801) Oxygen [Partial pressure] in Arterial blood

2.14

2.15

4.7

6.8

12.25

12.36

kpa

0.03

(3003396) Base excess in Arterial blood by calculation

2.12

2.09

4.7

6.8

-0.34

1.14

mmol/l

1.11

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

153

1.89

2.01

6.8

3.9

142.13

116.51

ng/l

0.08

112

(3016879) Cocaine [Presence] in Urine

2.31

1.97

1.4

2.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

281

1.70

1.91

1.7

1.8

93.93

93.98

pmol/l

0.00

141

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

189

1.78

1.87

2.5

2.3

—

(3027944) Amphetamines [Presence] in Urine

2.23

1.84

1.4

1.7

—

(3028300) Cannabinoids [Presence] in Urine

2.20

1.78

1.4

2.2

—

(3000764) Benzodiazepines [Presence] in Urine

2.20

1.78

1.4

2.2

—

(3027008) Opiates [Presence] in Urine

2.20

1.78

1.4

2.2

—

(3028707) Methadone [Presence] in Urine by Screen method

3.03

1.75

1.4

3.8

—

(40758558) Short blood count panel - Blood

224

1.65

1.57

7.5

7.9

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.27

1.56

1.3

2.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

2.69

1.54

2.3

1.2

—

(3019230) Fractional oxyhemoglobin in Venous blood

3.43

1.54

1.0

4.5

71.10

70.74

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

208

1.66

1.54

2.9

3.3

—

(3009508) Creatinine [Moles/volume] in Urine

269

1.60

1.53

3.2

3.3

10.21

8.96

mmol/l

0.45

234

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.02

1.37

1.2

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.02

1.37

1.2

1.1

—

(3031040) Bacteria [#/volume] in Urine by Automated count

529

1.50

1.36

5.2

3.8

—

4973.14

—

(3007853) Bacteria identified in Skin by Aerobe culture

107

1.80

1.35

1.6

—

(3022145) Colonoscopy Study observation

1.83

1.29

1.1

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.47

1.26

1.0

1.3

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

2.33

1.12

4.0

2.5

1.55

1.62

g/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.95

1.11

2.1

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

199

1.53

1.09

1.4

1.5

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

148

1.60

1.08

3.9

2.3

0.59

0.68

e6/l

0.13

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.08

1.07

1.6

1.1

—

(3002032) Base excess in Venous blood by calculation

1.78

1.07

5.8

5.2

1.05

1.96

mmol/l

0.55

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

386

1.41

1.00

3.9

4.1

18.16

22.18

0.94

157

(3016502) Oxygen saturation in Arterial blood

1.71

0.96

4.2

7.3

97.44

96.10

0.72

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.20

0.93

1.2

1.3

—

(3034770) Mitochondria Ab [Titer] in Serum

2.05

0.88

1.2

—

(3045414) Leukocytes [Presence] in Urine

2.05

0.88

1.3

1.4

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

218

1.44

0.86

1.5

1.7

1.76

1.45

mmol/l

0.57

181

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.92

0.83

1.7

2.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.92

0.83

1.0

1.1

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.66

0.82

2.5

2.0

0.22

0.24

g/l

0.35

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.80

0.0

4.6

—

33.00

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.78

0.0

4.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

2.22

0.77

1.0

1.2

—

(40768797) Stomach Pathology biopsy report

109

1.54

0.75

1.0

1.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

190

1.40

0.70

1.4

2.82

2.45

g/l

0.29

128

(36304419) Bacteria [Presence] in Urine

245

1.36

0.69

5.2

2.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

276

0.71

0.68

4.8

2.6

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.67

0.68

2.0

2.1

30.97

41.44

u/l

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

1.67

0.68

1.0

1.7

306.00

301.08

mu/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.82

0.67

1.4

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.68

0.63

1.4

1.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

114

1.47

0.63

5.4

6.7

106.00

104.24

mmol/l

0.93

114

(1616796) Gas panel - Central venous blood

0.00

0.60

0.0

2.4

—

(1761868) Lipid panel - Serum or Plasma

418

0.77

0.60

2.0

2.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.60

0.0

1.6

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.59

0.0

1.9

—

8.46

—

(40761536) Microorganisms panel - Urine sediment

0.56

0.59

2.0

2.7

—

(3049717) Cytology report of Urine Cyto stain

1.75

0.58

5.2

2.3

—

(3012516) Albumin [Mass/volume] in Urine

235

1.31

0.55

3.8

3.3

40.11

50.72

mg/l

0.18

159

(3012544) pH of Venous blood

1.50

0.54

6.6

5.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

145

1.37

0.53

4.3

2.4

1.10

1.34

e6/l

—

(3026008) Bacteria identified in Urine by Culture

192

1.31

0.50

3.8

2.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

116

0.67

0.48

1.4

1.8

—

(40761511) CBC panel - Blood by Automated count

109

1048

1.44

0.48

14.5

11.4

—

(40768804) Tissue Pathology biopsy report

318

1.24

0.44

1.7

2.0

—

(40761535) Cells panel - Urine sediment

1.46

0.43

2.3

4.0

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

160

0.72

0.43

1.8

1.7

582.42

447.71

pmol/l

0.54

136

(3021901) Oxygen saturation in Capillary blood

0.00

0.41

0.0

2.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.41

0.0

4.6

—

(3000492) Spirometry study

124

1.33

0.41

1.3

1.4

—

(4200892) Spirometry reversibility

1.36

0.41

1.1

1.4

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.41

0.0

1.4

—

65.24

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.8

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.40

0.0

1.8

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.40

0.0

3.3

—

7.32

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.39

0.0

3.4

—

1.28

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.39

0.0

1.1

—

(3030467) Casts [#/volume] in Urine by Automated count

256

1.23

0.38

4.8

2.4

0.34

0.37

e6/l

0.04

186

(3019225) pH of Specimen

0.64

0.37

4.2

5.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.42

0.35

1.0

1.8

—

(36660697) Celiac disease serology panel - Serum

1.38

0.33

1.2

—

(3023368) Bacteria identified in Blood by Culture

233

1.20

0.31

5.8

4.9

—

(3021589) Normoblasts [#/volume] in Blood

432

0.86

0.29

9.1

9.5

0.01

0.00

e9/l

0.46

359

(3022621) pH of Urine by Test strip

1.24

0.29

7.9

2.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

245

1.19

0.28

4.2

3.9

11.91

7.74

mg/mmol

0.23

167

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

323

1.16

0.27

4.6

2.8

—

(4035726) Immunohistochemistry procedure

0.69

0.27

1.4

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.22

0.25

5.7

4.4

1.94

14.09

ug/l

—

(3003694) ABO and Rh group [Type] in Blood

276

1.17

0.25

1.3

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.26

0.24

1.5

1.8

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

346

1.14

0.23

3.2

2.4

170.13

149.63

ug/l

0.20

319

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.74

0.23

1.4

2.2

414.71

390.48

nmol/l

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.29

0.23

1.0

1.2

—

(3044889) 12 lead EKG panel

644

1.13

0.23

3.5

—

(3002256) Pathology report gross observation

100

0.79

0.22

1.1

1.2

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.21

0.0

1.2

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.5

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

3.97

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

107.08

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

100

972

1.17

0.21

20.4

14.4

139.49

139.67

mmol/l

0.41

100

947

(3005719) IgG [Mass/volume] in Serum or Plasma

1.27

0.21

2.0

2.3

11.68

10.25

g/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

832

0.88

0.21

3.8

3.7

2.10

1.95

mu/l

0.24

763

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

341

0.88

0.21

2.7

3.4

203.42

39.45

ng/l

0.41

223

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.21

0.0

2.1

—

36.68

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.29

0.21

1.0

3.4

1.18

1.53

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.1

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.22

0.18

1.0

—

(3019060) Gas panel - Arterial blood

1.14

0.17

1.6

4.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

102

1.20

0.16

1.5

1.8

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.11

0.15

2.2

3.6

—

(3002582) Erythrocytes [#/volume] in Urine

288

1.10

0.13

5.1

2.5

10.36

50.29

e6/l

1.25

220

(40760892) CBC W Ordered Manual Differential panel - Blood

423

0.92

0.13

6.7

8.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

101

991

1.12

0.12

17.5

12.7

24.69

22.78

mg/l

0.24

773

(21494755) Public health laboratory ask at order entry panel

157

0.88

0.12

1.7

1.4

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

192

1.11

0.11

3.0

1.8

2.13

1.29

mg/l

0.22

150

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

359

0.93

0.10

4.9

3.2

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.07

0.09

1.0

3.4

0.56

0.72

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

134

0.88

0.09

1.1

1.5

—

(1002224) Polysomnography panel

1.10

0.09

1.2

1.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.78

0.08

2.4

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

294

1.07

0.08

2.1

2.8

0.47

0.78

ug/l

1.93

175

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

137

1.11

0.08

1.5

2.1

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.81

0.08

2.0

2.8

64.12

65.71

g/l

—

(3000494) Fungus identified in Specimen by Culture

108

1.12

0.07

1.2

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.84

0.07

1.1

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

122

0.89

0.07

1.9

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

171

0.93

0.05

1.3

1.8

—

(3018095) Leukocytes [#/volume] in Urine

330

1.04

0.03

5.4

3.1

58.93

136.78

e6/l

0.33

228

(3022217) INR in Platelet poor plasma by Coagulation assay

401

1.03

0.02

15.7

11.7

1.37

1.20

inr

—

117

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

712

1.03

0.02

3.0

3.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

923

1.03

0.01

17.5

11.6

86.60

87.60

ml/min/173m2

0.15

756

(3035350) Ketones [Presence] in Urine by Test strip

464

1.02

0.00

4.1

3.1

0.00

0.01

estimate

—

102

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

146

1.03

0.00

2.1

2.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.01

0.00

5.3

8.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

131

0.99

0.00

2.1

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

238

1.01

0.00

1.5

2.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

922

0.99

0.00

3.9

4.1

5.99

5.91

mmol/l

0.32

852

(3037467) Urinalysis macro (dipstick) panel - Urine

618

1.01

0.00

5.0

3.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

193

0.98

0.00

1.2

1.8

—

(3006315) Basophils [#/volume] in Blood

457

1.01

0.00

7.4

7.2

0.04

e9/l

0.33

403

(3021601) Nitrite [Presence] in Urine by Test strip

465

0.98

0.00

5.7

4.2

0.00

estimate

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

105

0.95

0.00

1.2

1.7

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.4

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1399.89

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.2

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.3

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

-0.00

0.0

1.5

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.2

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

-0.00

0.0

1.6

—

7.20

—

(37021073) Hepatitis C virus genotype in Serum or Plasma by Sequencing

0.00

-0.00

0.0

1.0

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

-0.00

0.0

1.0

—

(3015183) Erythrocyte sedimentation rate

0.00

-0.00

0.0

1.2

—

(3014271) Vancomycin [Susceptibility]

0.00

-0.00

0.0

1.8

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3014043) Spermatozoa Nonprogressive/100 spermatozoa in Semen

0.00

-0.00

0.0

3.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.3

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

3.4

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

105.00

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.5

—

153.00

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.1

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3035880) pH of Pleural fluid

0.00

-0.00

0.0

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.01

-0.00

1.2

1.6

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40758292) HTLV I+II Ab panel - Serum

0.00

-0.00

0.0

1.8

—

(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.4

—

95.40

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.2

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

1.43

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.3

—

392.50

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3025941) Bacteria identified in Stool by Culture

0.91

-0.00

1.6

1.2

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

4.2

—

10.09

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

40.00

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

1.06

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3022689) Creatine [Moles/volume] in Urine

0.00

-0.00

0.0

1.8

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.6

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

1.02

-0.00

2.2

7.7

21.25

23.81

mmol/l

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.2

—

3.80

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(40761995) Spermatozoa Progressive [#/volume] in Semen

0.00

-0.00

0.0

1.6

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

7.1

—

12.02

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.5

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_EXPLOSION_OTHER_MATERI – Explosion of other materials

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Explosion of other materials

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Explosion of other materials (VWXY20_EXPLOSION_OTHER_MATERI)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints