Explosion of other materials

VWXY20_EXPLOSION_OTHER_MATERI

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — W40 Cause of death: ICD-10 — W40 2 out of 7 registries used, show all original rules.	118
4. Check minimum number of events None	118
5. Include endpoints None	118
6. Filter based on genotype QC (FinnGen only)	118

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 5
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: W[2-4]

NAME	VWXY20_EXPLOSION_OTHER_MATERI
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	W40
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	W40
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Explosion of other materials based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	118	25	93
Unadjusted period prevalence (%)	0.03	0.01	0.04
Median age at first event (years)	44.09	44.77	43.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
107: Matched controls
1070

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

W40

ICD-10 Finland

Explosion of other materials

+∞

136.8

100

X58

ICD-10 Finland

Exposure to other specified factors

3.6

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3044640) Blood type and Crossmatch panel - Blood

272

2.37

4.81

2.3

2.2

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

10.53

4.06

2.0

1.6

—

(3042936) Bacteria identified in Isolate by Culture

120

2.37

3.28

2.3

1.7

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

106

2.32

2.85

3.0

2.3

19.03

25.27

1.08

(3011288) Drugs identified in Urine by Screen method

2.92

2.63

1.6

3.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

390

1.83

2.63

3.6

3.9

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.93

2.45

3.6

8.4

—

(3013512) EKG study

247

0.39

2.42

3.7

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

2.22

2.32

4.7

6.9

4.98

5.03

kpa

0.08

(3027801) Oxygen [Partial pressure] in Arterial blood

2.22

2.32

4.7

6.9

12.25

12.48

kpa

0.06

(3003396) Base excess in Arterial blood by calculation

2.19

2.26

4.7

6.8

-0.34

1.15

mmol/l

1.11

(3000991) Gas panel - Venous blood

2.31

2.20

8.1

7.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

150

1.94

2.13

6.8

3.9

142.13

119.61

ng/l

0.07

109

(3016879) Cocaine [Presence] in Urine

2.39

2.10

1.4

2.3

—

(3027944) Amphetamines [Presence] in Urine

2.35

2.04

1.4

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

185

1.83

2.01

2.5

2.3

—

(3000764) Benzodiazepines [Presence] in Urine

2.31

1.97

1.4

2.3

—

(3028300) Cannabinoids [Presence] in Urine

2.31

1.97

1.4

2.3

—

(3027008) Opiates [Presence] in Urine

2.31

1.97

1.4

2.3

—

(3028707) Methadone [Presence] in Urine by Screen method

3.17

1.83

1.4

3.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

276

1.68

1.81

1.7

1.8

95.77

94.20

pmol/l

0.10

137

(40758558) Short blood count panel - Blood

219

1.70

1.72

7.5

7.9

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.37

1.69

1.3

2.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

203

1.71

1.69

2.9

3.3

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

2.91

1.68

2.3

1.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

520

1.56

1.55

5.2

3.8

—

4973.14

—

(3019230) Fractional oxyhemoglobin in Venous blood

3.43

1.54

1.0

4.5

71.10

70.74

—

(3009508) Creatinine [Moles/volume] in Urine

261

1.61

1.51

3.2

3.3

10.43

8.94

mmol/l

0.55

225

(40760892) CBC W Ordered Manual Differential panel - Blood

206

0.49

1.48

3.4

6.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

106

1.82

1.39

1.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.02

1.37

1.2

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.02

1.37

1.2

1.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.58

1.32

1.0

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

196

1.56

1.17

1.4

1.5

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

146

1.62

1.14

3.9

2.3

0.59

0.68

e6/l

0.12

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

2.34

1.12

4.0

2.5

1.55

1.62

g/l

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

2.44

1.10

1.0

1.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.08

1.08

1.6

1.1

—

(3016502) Oxygen saturation in Arterial blood

1.78

1.07

4.2

7.4

97.44

96.16

0.67

(3022145) Colonoscopy Study observation

1.70

0.99

1.1

1.4

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

378

1.40

0.98

4.0

4.1

17.91

22.21

0.96

152

(3034770) Mitochondria Ab [Titer] in Serum

2.29

0.95

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.20

0.93

1.2

1.3

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

215

1.46

0.93

1.5

1.7

1.76

1.46

mmol/l

0.56

178

(3045414) Leukocytes [Presence] in Urine

2.12

0.90

1.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.70

0.89

2.5

2.0

0.22

0.24

g/l

0.32

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.92

0.83

1.7

2.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.92

0.83

1.0

1.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

100

928

1.51

0.82

21.4

13.0

41.36

41.95

0.29

759

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.79

0.82

2.2

1.8

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.80

0.0

4.6

—

33.00

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.79

0.0

4.0

—

(3049717) Cytology report of Urine Cyto stain

1.80

0.77

5.2

2.3

—

(36304419) Bacteria [Presence] in Urine

242

1.38

0.75

5.2

2.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

188

1.42

0.74

1.4

2.82

2.42

g/l

0.32

126

(3021387) Prolactin [Units/volume] in Serum or Plasma

1.71

0.70

1.0

1.7

306.00

303.27

mu/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.89

0.69

1.4

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.68

0.63

1.4

1.3

—

(3026008) Bacteria identified in Urine by Culture

185

1.37

0.62

3.7

2.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

271

0.73

0.61

4.8

2.6

—

(1616796) Gas panel - Central venous blood

0.00

0.60

0.0

2.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.60

0.0

1.6

—

(40761535) Cells panel - Urine sediment

1.55

0.60

2.3

4.2

—

(42870588) Differential panel, method unspecified - Blood

298

1.30

0.59

6.4

7.0

—

(40761536) Microorganisms panel - Urine sediment

0.56

0.59

2.0

2.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

143

1.39

0.57

4.3

2.5

1.10

1.36

e6/l

—

(40768797) Stomach Pathology biopsy report

108

1.45

0.56

1.0

1.3

—

(1761868) Lipid panel - Serum or Plasma

413

0.78

0.54

2.0

2.5

—

(3012516) Albumin [Mass/volume] in Urine

228

1.30

0.52

3.8

3.4

40.11

50.93

mg/l

0.19

152

(3019832) Treponema pallidum Ab [Presence] in Serum

116

0.67

0.48

1.4

1.8

—

(40768804) Tissue Pathology biopsy report

315

1.25

0.48

1.7

2.0

—

(3015736) pH of Urine

354

1.24

0.47

3.4

3.1

—

(40761511) CBC panel - Blood by Automated count

107

1029

1.43

0.46

14.7

11.5

—

(3030467) Casts [#/volume] in Urine by Automated count

252

1.26

0.44

4.8

2.4

0.34

0.37

e6/l

0.05

182

(4010399)

1.41

0.42

1.1

1.4

—

(3032080) INR in Blood by Coagulation assay

339

1.22

0.42

12.9

7.1

1.40

1.18

inr

—

106

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

159

0.73

0.41

1.8

1.7

582.42

448.89

pmol/l

0.54

135

(3021901) Oxygen saturation in Capillary blood

0.00

0.41

0.0

2.1

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.41

0.0

1.4

—

66.00

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.9

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.41

0.0

4.6

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.41

0.0

3.4

—

7.43

—

(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose

0.00

0.41

0.0

1.2

—

8.71

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.9

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.40

0.0

3.6

—

1.27

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.39

0.0

1.1

—

(3023368) Bacteria identified in Blood by Culture

228

1.24

0.38

5.9

5.0

—

(3000492) Spirometry study

117

1.32

0.37

1.2

1.4

—

(36660697) Celiac disease serology panel - Serum

1.40

0.36

1.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.42

0.35

1.0

1.8

—

(3012544) pH of Venous blood

1.38

0.35

7.1

5.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

334

0.83

0.35

2.8

3.5

212.12

39.60

ng/l

0.41

218

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

317

1.20

0.34

4.7

2.8

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

821

0.85

0.30

3.8

2.04

1.94

mu/l

0.14

752

(3003694) ABO and Rh group [Type] in Blood

272

1.19

0.30

1.3

1.4

—

(3022621) pH of Urine by Test strip

1.24

0.29

7.9

2.2

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

342

1.16

0.28

3.2

2.4

170.13

148.54

ug/l

0.21

316

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.29

0.27

1.5

1.8

—

(3019225) pH of Specimen

0.65

0.26

4.2

5.1

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.23

0.26

5.7

4.4

1.94

14.26

ug/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

238

1.17

0.25

4.1

4.2

11.91

7.67

mg/mmol

0.24

162

(3005719) IgG [Mass/volume] in Serum or Plasma

1.31

0.25

2.0

2.3

11.68

10.23

g/l

—

(3044889) 12 lead EKG panel

633

1.14

0.24

3.5

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.37

0.24

1.0

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.75

0.23

1.4

2.2

414.71

397.39

nmol/l

—

(3021589) Normoblasts [#/volume] in Blood

425

0.88

0.23

9.1

9.6

0.01

0.00

e9/l

0.46

353

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.25

0.22

1.5

1.9

—

(3002256) Pathology report gross observation

100

0.79

0.22

1.1

1.2

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.4

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.21

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

107.08

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

3.97

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.21

0.0

2.1

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.20

0.0

2.1

—

524.17

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.22

0.18

1.0

—

(3019060) Gas panel - Arterial blood

1.20

0.18

1.6

4.5

—

(3002582) Erythrocytes [#/volume] in Urine

284

1.12

0.17

5.1

2.5

10.36

50.67

e6/l

1.25

218

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

187

1.15

0.17

3.0

1.9

2.13

1.31

mg/l

0.22

145

(4035726)

0.71

0.17

1.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

957

1.14

0.16

20.7

14.4

139.46

139.68

mmol/l

0.51

931

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.11

0.15

2.2

3.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

133

1.15

0.12

1.5

2.1

—

(3000494) Fungus identified in Specimen by Culture

106

1.15

0.10

1.2

1.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.09

0.10

1.0

3.5

1.26

1.50

—

(21494755) Public health laboratory ask at order entry panel

155

0.89

0.09

1.7

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

974

1.10

0.09

17.8

12.7

24.97

22.76

mg/l

0.28

758

(1002224) Polysomnography panel

1.10

0.09

1.2

1.1

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

1.08

0.09

2.2

7.7

21.25

23.82

mmol/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.80

0.08

2.4

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.82

0.08

2.0

2.8

64.12

65.68

g/l

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.84

0.07

1.1

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

454

1.06

0.07

4.1

3.1

0.00

estimate

—

(3018095) Leukocytes [#/volume] in Urine

325

1.06

0.07

5.4

3.1

58.93

136.73

e6/l

0.32

227

(3037467) Urinalysis macro (dipstick) panel - Urine

604

1.06

0.07

5.0

3.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

132

0.90

0.07

1.1

1.5

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

287

1.06

0.06

2.1

2.8

0.47

0.78

ug/l

1.78

169

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

120

0.91

0.05

1.9

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

352

0.95

0.05

4.9

3.2

—

(3006315) Basophils [#/volume] in Blood

448

1.04

0.04

7.4

7.3

0.04

e9/l

0.31

395

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

702

1.03

0.02

3.0

3.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

166

0.96

0.00

1.3

1.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

234

1.03

0.00

1.5

2.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

906

0.97

0.00

3.9

4.1

5.97

5.91

mmol/l

0.26

836

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

188

1.01

0.00

1.2

1.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

103

0.97

0.00

1.2

1.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

145

1.04

0.00

2.1

2.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

456

1.01

0.00

5.7

4.2

0.00

estimate

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.0

1.0

—

105.00

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.6

—

40.00

—

(4146454)

0.00

0.0

1.8

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.6

—

7.20

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.91

0.00

5.8

8.4

—

(3000012) Reticulocyte production index

0.00

0.0

2.6

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.4

—

95.40

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.2

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(44813793)

0.00

0.0

1.0

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.6

—

(37021073) Hepatitis C virus genotype in Serum or Plasma by Sequencing

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(40758292) HTLV I+II Ab panel - Serum

0.00

0.0

1.8

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.6

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3035880) pH of Pleural fluid

0.00

0.0

1.0

—

(3022689) Creatine [Moles/volume] in Urine

0.00

0.0

1.8

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.2

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.00

0.00

1.2

1.6

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.3

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

4.5

—

(42870298) TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative

0.00

0.0

1.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

0.0

7.1

—

12.03

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

1.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.2

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.1

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.3

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.3

—

392.50

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

130

1.00

0.00

2.1

2.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

1.06

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.1

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

3.4

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.2

—

3.80

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.3

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.1

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

2.7

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1399.89

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.2

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.5

—

153.00

—

(3025941) Bacteria identified in Stool by Culture

0.91

0.00

1.8

1.2

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.0

4.2

—

10.09

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

910

1.00

0.00

17.8

11.6

86.94

87.53

ml/min/173m2

0.08

744

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.5

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.3

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_EXPLOSION_OTHER_MATERI – Explosion of other materials

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Explosion of other materials

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Explosion of other materials (VWXY20_EXPLOSION_OTHER_MATERI)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints