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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Lymph nodes

CD2_BENIGN_LYMPHNODES_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D36.0&
  • Hospital discharge: ICD-9 2298A
  • Cause of death: ICD-10 D36.0&
  • Cause of death: ICD-9 2298A

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D36
Name in latin
Neoplasma benignum lymphonodorum

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 96 65 31
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 47.07 45.60 50.15

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
87
Matched controls
870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D36.0
ICD-10 Finland
Benign neoplasm: Lymph nodes
+∞
117.2
84
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
+∞
16.1
15
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
20.7
7.8
11
6
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
15.9
6.6
10
7
PJA10
NOMESCO Finland
Exploration of lymph nodes
75.1
6.5
7
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
15
9.00
9.07
1.7
1.1
—
—
—
0
0
5
0
+∞
5.25
1.0
0.0
—
—
—
0
0
59
371
2.53
4.63
7.2
4.9
0.6
0.6
e9/l
0.15
52
315
60
382
2.52
4.56
7.5
5.2
0.2
0.2
e9/l
0.44
53
334
59
373
2.51
4.55
7.4
4.9
0.0
0.0
e9/l
0.61
52
318
59
381
2.42
4.23
7.2
4.9
1.9
1.9
e9/l
0.02
52
330
30
152
2.42
3.62
6.5
3.7
—
—
—
0
0
32
169
2.34
3.51
4.5
4.0
—
—
—
0
0
17
72
2.65
2.92
3.8
2.8
1.0
1.0
mmol/l
0.22
17
63
37
225
2.05
2.78
3.3
3.1
—
—
—
0
0
58
414
2.01
2.77
10.9
6.0
4.0
4.2
e9/l
0.38
52
356
30
175
2.04
2.48
5.2
3.7
1.0
1.0
kg/l
—
6
22
39
251
1.93
2.44
2.4
1.6
—
—
—
0
0
6
12
5.25
2.44
1.2
1.3
—
—
—
0
0
6
12
5.25
2.44
1.3
2.3
—
—
—
0
0
50
350
1.89
2.43
7.7
4.6
55.5
56.3
%
0.17
45
330
43
287
1.90
2.41
3.3
3.4
28.6
46.7
ng/l
0.72
27
177
54
390
1.88
2.36
6.9
4.9
0.0
0.0
estimate
—
9
70
54
390
1.88
2.36
4.8
3.5
0.0
0.0
estimate
—
9
73
23
124
2.12
2.33
2.2
1.6
—
—
—
0
0
35
222
1.91
2.26
3.3
3.2
—
—
—
0
0
37
243
1.85
2.13
7.6
4.6
—
—
—
0
0
18
91
2.20
2.12
2.3
1.4
—
—
—
0
0
12
51
2.55
2.04
2.5
1.4
—
—
—
0
0
5
11
4.73
1.96
2.0
1.0
—
—
—
0
0
13
59
2.39
1.94
1.4
1.1
—
—
—
0
0
13
59
2.39
1.94
2.1
1.4
—
—
—
0
0
53
397
1.75
1.92
4.9
3.5
0.0
0.0
estimate
—
9
69
66
528
1.80
1.88
6.2
4.0
—
—
—
0
0
13
60
2.35
1.87
2.1
2.3
—
—
—
0
0
5
12
4.33
1.84
2.2
1.0
—
—
—
0
0
7
27
2.71
1.54
2.0
1.7
—
—
—
0
0
6
21
2.98
1.53
3.0
3.3
—
—
—
0
0
16
91
1.91
1.39
4.0
2.0
0.8
0.8
mmol/l
1.99
16
85
5
17
3.04
1.37
1.0
1.2
—
—
—
0
0
41
308
1.58
1.34
5.0
3.3
—
—
—
0
0
24
159
1.68
1.28
2.4
2.0
—
—
—
0
0
30
212
1.60
1.25
8.3
2.6
7.4
7.4
ph
—
6
37
21
136
1.70
1.21
1.6
1.9
709.8
450.2
pmol/l
0.79
16
116
18
112
1.75
1.19
2.1
1.5
250.0
905.7
titre
—
8
28
11
58
2.01
1.17
2.0
1.9
0.2
0.2
g/l
1.08
11
49
39
298
1.52
1.15
6.1
3.3
35.1
36.1
g/l
0.50
39
283
29
208
1.56
1.13
4.9
3.7
0.0
0.0
estimate
—
7
73
5
21
2.45
1.10
3.2
3.7
—
—
—
0
0
23
158
1.60
1.07
1.6
1.3
10.8
28.5
iu/ml
—
6
52
68
590
1.52
1.05
6.2
3.8
14.0
10.4
mm/h
0.78
62
550
62
528
1.49
1.05
3.5
3.4
—
—
—
0
0
7
35
2.08
1.02
4.3
4.1
—
—
—
0
0
9
50
1.88
1.00
3.6
3.4
—
—
—
0
0
22
152
1.58
1.00
1.6
1.3
1.3
10.8
u/ml
—
8
60
9
51
1.84
0.98
1.1
1.3
—
—
—
0
0
36
279
1.46
0.97
4.1
3.5
30.5
78.5
e6/l
0.99
30
193
30
226
1.48
0.92
2.1
1.8
2.4
2.3
mmol/l
0.76
30
197
26
192
1.49
0.88
1.4
1.3
0.9
1.7
u/ml
—
10
45
8
46
1.81
0.85
2.4
4.3
—
—
—
0
0
28
212
1.45
0.83
3.1
1.8
—
—
—
0
0
25
187
1.46
0.79
5.8
3.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
13
84
1.63
0.76
2.0
1.9
—
—
—
0
0
7
39
1.86
0.74
2.7
4.2
25.8
25.3
mmol/l
—
7
39
7
39
1.86
0.74
1.9
2.1
—
—
—
0
0
5
25
2.05
0.74
1.4
1.2
—
—
—
0
0
14
94
1.57
0.71
2.1
1.9
2.4
2.3
g/l
0.08
14
88
7
43
1.68
0.68
4.9
3.0
—
—
—
0
0
67
730
0.73
0.66
24.2
11.7
38.7
40.7
%
1.10
46
557
8
51
1.62
0.62
3.6
2.5
—
—
—
0
0
20
151
1.41
0.60
3.7
3.3
116.8
130.1
ng/l
0.06
14
106
6
36
1.71
0.58
1.0
1.1
—
—
—
0
0
33
276
1.30
0.52
13.2
8.2
1.4
1.2
inr
—
10
81
12
86
1.45
0.47
1.4
1.7
—
—
—
0
0
26
311
0.78
0.47
3.2
2.7
—
—
—
0
0
17
131
1.36
0.46
1.5
1.9
2.5
2.4
mmol/l
0.90
17
110
39
339
1.25
0.45
18.0
7.1
0.0
0.0
e9/l
0.00
34
269
8
59
1.39
0.42
1.1
1.2
—
—
—
0
0
13
97
1.39
0.42
2.9
1.7
—
—
—
0
0
80
836
0.74
0.42
23.3
10.4
—
—
—
0
0
5
34
1.50
0.41
1.0
1.4
—
—
—
0
0
5
34
1.50
0.41
1.0
1.4
—
—
—
0
0
5
35
1.45
0.40
1.0
1.4
—
—
—
0
0
5
35
1.45
0.40
1.0
1.4
—
—
—
0
0
9
66
1.40
0.40
3.6
3.1
—
—
—
0
0
6
43
1.42
0.36
2.5
3.4
6.0
9.2
mmol/l
—
6
43
6
44
1.39
0.35
2.7
1.8
8.2
15.4
nmol/l
—
6
39
6
46
1.32
0.33
2.3
1.1
—
—
—
0
0
24
205
1.23
0.31
3.3
2.7
—
—
—
0
0
9
120
0.72
0.29
1.1
1.2
—
—
—
0
0
34
304
1.18
0.28
2.2
1.9
91.2
98.2
pmol/l
0.44
19
137
12
95
1.30
0.28
3.3
1.9
—
—
—
0
0
19
220
0.83
0.25
4.4
3.9
8.3
8.0
mg/mmol
0.01
13
145
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
7
58
1.22
0.18
2.9
2.9
—
—
—
0
0
8
71
1.14
0.16
1.0
1.3
—
—
—
0
0
19
208
0.89
0.12
4.9
3.4
—
—
—
0
0
81
794
1.13
0.10
24.3
10.7
22.4
20.6
mg/l
0.23
66
594
17
186
0.90
0.10
10.5
4.8
—
—
—
0
0
6
56
1.08
0.09
3.5
2.5
124.8
76.2
ng/l
—
6
49
7
67
1.05
0.08
1.9
2.6
5.7
6.1
ug/l
—
7
58
7
80
0.87
0.07
1.4
1.5
—
—
—
0
0
10
90
1.12
0.05
2.0
1.4
—
—
—
0
0
10
91
1.11
0.04
3.5
1.3
—
—
—
0
0
82
827
0.94
0.01
26.1
12.3
71.7
73.4
umol/l
0.43
82
827
22
227
0.96
0.01
2.8
3.0
7.1
7.7
mmol/l
0.25
17
191
20
203
0.98
0.00
3.3
3.2
3030.5
49.1
mg/l
0.49
14
132
21
206
1.02
0.00
2.1
1.4
—
—
—
0
0
8
79
1.01
0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
430.2
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
7
74
0.94
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
1.7
—
0
7
0
6
0.00
0.00
0.0
1.3
—
43.5
—
0
6
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_LYMPHNODES_EXALLC – Benign neoplasm: Lymph nodes

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).