No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF8
- Parent code in ICD-10
- C81-C96
- Name in latin
- Leuc(h)aemia monocytica
Similar endpoints
↥List of similar endpoints to
Monocytic leukaemia
based on the number of shared cases.
Similar with more cases:
- Monocytic leukaemia
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 111 | 47 | 64 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 65.71 | 60.56 | 69.49 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 101
- Matched controls
- 1011
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
396.6
60.3
55
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
46.5
41
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
36.7
33
*
XW000
NOMESCO Finland
Bone marrow biopsy
41.3
31.5
39
15
WW500
NOMESCO Finland
Blood transfusion
100.2
27.5
29
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
294.0
23.7
23
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
21.6
20
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
21.6
20
*
A04AA01
ATC
ondansetron; systemic, rectal
55.3
19.1
22
5
D64.9
ICD-10 Finland
Anaemia, unspecified
9.7
16.1
35
52
Z51.5
ICD-10 Finland
Palliative care
20.0
14.2
21
13
R50.9
ICD-10 Finland
Fever, unspecified
7.0
13.0
35
71
L03AA02
ATC
filgrastim; parenteral
+∞
12.8
12
*
M04AA01
ATC
allopurinol; systemic
6.3
12.0
35
78
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
134.7
11.7
12
*
C93.9
ICD-10 Finland
Monocytic leukaemia, unspecified
+∞
11.7
11
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
24.8
11.1
15
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.3
10.9
31
66
B03XA02
ATC
darbepoetin alfa; parenteral
122.2
10.6
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.8
10.0
30
68
L01XX05
ATC
hydroxycarbamide; oral
30.5
8.7
11
*
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
8.4
8
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
8.4
8
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
10.8
8.1
15
16
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
86.1
7.5
8
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
86.1
7.5
8
*
J05AB11
ATC
valaciclovir; oral
4.9
7.5
25
63
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.4
7
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.4
7
*
A41.9
ICD-10 Finland
Sepsis, unspecified
9.1
6.6
13
16
A03FA01
ATC
metoclopramide; systemic, rectal
5.2
6.5
20
46
127
Kela drug reimbursment
Transplant complication
28.7
6.3
8
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
6.3
6
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
3.5
6.3
31
112
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
19
18.46
30.73
6.0
1.8
—
—
—
0
0
16
16
11.52
14.37
3.2
1.3
—
—
—
0
0
16
17
10.83
13.78
3.0
1.3
—
—
—
0
0
14
13
12.18
13.12
3.2
1.3
—
—
—
0
0
41
124
4.66
12.95
7.4
2.0
0.8
0.8
mmol/l
0.03
41
114
12
14
9.49
9.53
1.8
1.1
—
—
—
0
0
14
21
7.48
9.13
1.4
1.3
—
—
—
0
0
8
0
+∞
8.43
1.0
0.0
—
—
—
0
0
14
23
6.82
8.40
1.6
1.3
—
—
—
0
0
21
54
4.56
7.85
2.9
1.4
—
—
—
0
0
10
5
21.76
7.27
2.5
3.6
—
—
—
0
0
10
5
21.76
7.27
2.5
3.6
—
—
—
0
0
10
7
15.52
6.53
4.0
1.9
—
—
—
0
0
40
185
2.82
6.00
16.7
1.9
—
—
—
0
0
10
17
6.37
5.73
2.6
1.2
—
—
—
0
0
33
141
2.91
5.69
3.9
1.7
—
—
—
0
0
14
34
4.57
5.54
3.4
1.1
—
—
—
0
0
5
0
+∞
5.24
1.0
0.0
—
—
—
0
0
9
9
10.75
5.13
1.7
1.0
—
—
—
0
0
25
97
3.04
5.07
2.8
1.7
—
—
—
0
0
18
57
3.58
5.02
1.7
1.5
—
—
—
0
0
25
99
2.97
4.88
2.7
1.8
—
—
—
0
0
61
376
2.38
4.79
25.6
3.6
—
—
—
0
0
8
8
10.65
4.60
1.3
1.4
—
—
—
0
0
11
26
4.59
4.47
1.4
1.6
0.1
0.5
iu/ml
—
6
5
24
99
2.82
4.34
4.2
3.9
5.7
5.9
kpa
0.34
24
94
7
6
12.33
4.33
1.9
1.2
—
—
—
0
0
18
64
3.16
4.19
1.3
2.1
0.2
0.2
g/l
0.01
18
53
65
429
2.24
4.15
16.4
5.0
1.2
1.2
mmol/l
1.11
58
365
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
7
7
10.56
4.07
5.1
1.3
—
—
—
0
0
7
8
9.24
3.83
5.1
1.4
—
—
—
0
0
8
13
6.53
3.57
2.0
1.2
—
—
—
0
0
59
391
2.09
3.55
14.7
4.8
1.2
1.2
mmol/l
0.80
59
346
6
7
8.97
3.30
5.7
1.4
—
—
—
0
0
72
880
0.48
3.13
5.1
4.5
4.1
4.5
mmol/l
1.61
66
797
8
16
5.30
3.11
1.9
1.3
—
—
—
0
0
8
16
5.30
3.11
1.9
1.3
—
—
—
0
0
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
6
8
7.84
3.09
3.3
1.1
—
—
—
0
0
51
334
1.97
3.05
5.9
3.0
—
—
—
0
0
71
869
0.49
3.02
4.8
4.5
1.2
1.5
mmol/l
3.61
64
781
75
900
0.49
2.95
5.4
5.1
2.4
2.6
mmol/l
0.94
68
813
7
15
4.90
2.64
1.1
1.1
—
—
—
0
0
7
15
4.90
2.64
1.4
1.1
—
—
—
0
0
44
287
1.88
2.57
4.0
2.5
49.9
31.7
u/l
0.40
44
273
5
7
7.41
2.57
1.4
1.1
—
—
—
0
0
69
839
0.53
2.53
4.9
4.1
1.5
1.3
mmol/l
1.29
63
747
8
21
4.02
2.51
1.9
1.4
—
—
—
0
0
6
12
5.22
2.43
1.5
1.2
—
—
—
0
0
6
12
5.22
2.43
1.5
1.2
—
—
—
0
0
8
22
3.83
2.41
1.6
1.3
—
—
—
0
0
5
8
6.48
2.39
3.8
1.1
—
—
—
0
0
5
8
6.48
2.39
3.8
1.1
—
—
—
0
0
9
28
3.40
2.36
3.2
3.5
—
—
—
0
0
6
13
4.81
2.30
1.5
1.2
—
—
—
0
0
7
18
4.08
2.29
1.7
1.6
—
—
—
0
0
15
70
2.32
2.09
6.9
2.5
4.8
5.1
kpa
0.45
15
59
5
10
5.18
2.09
1.0
1.0
—
—
—
0
0
6
16
3.90
1.96
14.7
2.9
52.0
64.8
%
—
6
16
5
11
4.70
1.96
1.0
1.3
—
—
—
0
0
9
34
2.79
1.91
6.7
1.8
—
—
—
0
0
17
88
2.10
1.87
6.4
3.4
—
—
—
0
0
7
23
3.18
1.83
1.7
1.2
—
—
—
0
0
24
144
1.85
1.76
4.9
2.8
0.8
2.4
e6/l
0.91
17
84
6
19
3.28
1.68
1.2
1.2
—
—
—
0
0
5
14
3.69
1.63
1.2
1.1
—
—
—
0
0
25
157
1.76
1.58
4.5
2.5
1.3
1.2
e6/l
0.05
18
97
5
15
3.44
1.54
3.6
1.1
21.8
17.3
iu/l
—
5
15
26
167
1.73
1.52
1.2
1.3
1.1
1.5
u/ml
—
9
48
11
54
2.15
1.38
3.0
1.7
—
—
—
0
0
85
938
0.60
1.37
52.1
15.3
92.7
81.7
umol/l
1.68
85
938
14
78
1.91
1.28
6.5
5.2
1.3
1.4
mmol/l
0.14
14
71
18
111
1.74
1.21
5.8
5.6
11.1
10.9
kpa
0.08
18
104
18
111
1.74
1.21
5.8
5.6
4.9
5.2
kpa
0.60
18
104
5
20
2.57
1.16
4.6
5.6
50.0
34.3
mg/l
—
5
14
10
51
2.06
1.15
7.1
7.0
0.9
0.7
%
—
10
51
7
30
2.42
1.14
3.3
1.7
—
—
—
0
0
5
21
2.44
1.10
1.0
2.1
13.0
17.9
u/ml
—
5
14
10
52
2.01
1.10
7.1
7.0
1.8
1.6
%
—
10
52
74
830
0.67
1.09
6.5
6.4
40.8
41.0
mmol/mol
0.06
67
755
52
421
1.44
1.08
6.3
3.7
0.0
0.0
estimate
0.00
11
72
79
874
0.67
1.07
5.8
4.8
6.4
6.1
mmol/l
0.61
74
776
36
273
1.47
1.05
5.1
2.7
0.8
0.4
e6/l
0.53
31
210
53
433
1.43
1.04
6.1
3.7
0.0
0.0
estimate
0.00
12
69
9
49
1.91
1.01
1.9
2.3
2.0
1.1
%
—
9
49
52
426
1.42
1.00
7.5
5.0
0.0
0.0
estimate
0.00
12
70
47
383
1.39
0.91
3.9
3.9
37.5
50.3
ng/l
0.37
35
288
31
237
1.43
0.85
8.0
4.0
0.0
0.0
estimate
—
9
69
76
827
0.74
0.69
38.2
12.4
69.2
76.0
ml/min/173m2
1.30
66
664
40
331
1.33
0.67
7.1
4.1
—
—
—
0
0
16
113
1.49
0.65
6.1
5.6
1.8
1.7
mmol/l
0.03
11
94
8
49
1.68
0.64
10.1
6.9
22.9
25.3
mmol/l
—
8
42
5
30
1.70
0.62
1.2
1.2
—
—
—
0
0
5
30
1.70
0.62
1.2
1.2
—
—
—
0
0
47
402
1.29
0.62
2.9
2.0
83.9
92.3
pmol/l
0.72
30
208
6
38
1.61
0.55
1.5
1.3
—
—
—
0
0
71
648
1.27
0.52
5.5
3.8
14.8
14.9
pmol/l
0.08
66
579
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
1.3
—
0
13
16
130
1.27
0.31
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
8.8
—
0
11
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
7.2
—
0
5
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
33
301
1.14
0.20
4.0
3.9
25.9
24.7
%
0.13
17
140
15
128
1.20
0.19
1.4
1.3
1.2
16.5
u/ml
—
5
40
10
87
1.16
0.10
2.5
1.8
1.6
1.7
%
—
10
76
48
461
1.07
0.09
3.4
2.9
—
—
—
0
0
6
71
0.84
0.08
3.2
2.1
8.7
15.6
nmol/l
—
6
61
10
90
1.12
0.05
2.0
1.3
—
—
—
0
0
11
107
1.03
0.00
10.7
7.8
—
—
—
0
0
87
874
0.98
0.00
50.0
13.3
30.2
23.7
mg/l
1.18
80
679
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
11.7
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
75.9
—
0
9
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: CD2_MONOCYTIC_LEUKAEMIA_EXALLC – Monocytic leukaemia
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).