Marasmic kwashiorkor

E4_MARAKWASH

kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning 'displaced child'. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E42
Cause of death: ICD-10 E42

2 out of 7 registries used, show all original rules.

64

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Check minimum number of events None

64

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Include endpoints None

64

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Remove individuals based on genotype QC

58

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E4_MARAKWASH

Control definitions

Control exclude E4_MALNUTRITION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E40-E46
Name in latin Malnutritio gravis ex deficientia proteino-energetica

Summary Statistics

Key figures

All Female Male
Number of individuals 58 37 21
Unadjusted prevalence (%) 0.02 0.02 0.01
Mean age at first event (years) 47.38 46.24 49.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_MARAKWASH – Marasmic kwashiorkor
GWS hits:

Survival analyses between endpoints

Plot

before Marasmic kwashiorkor
after Marasmic kwashiorkor

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Drugs most likely to be purchased after Marasmic kwashiorkor

Endpoint not on priority list, no data to show.