Familial chondrocalcinosis

FAMIL_CHONDROCALC

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M11.1 Cause of death: ICD-10 — M11.1 2 out of 7 registries used, show all original rules.	40
4. Check minimum number of events None	40
5. Include endpoints None	40
6. Filter based on genotype QC (FinnGen only)	40

Control definitions (FinnGen only)

Control exclude: RHEUMA_CHRYSTAL

Extra metadata

First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M11
Name in latin: Chondrocalcinosis familialis

NAME	FAMIL_CHONDROCALC
CONTROL_EXCLUDE	RHEUMA_CHRYSTAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M111
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M111
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Familial chondrocalcinosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	163	90	73
Only index persons	152	84	68
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	72.92	75.09
Only index persons	73.61	72.72	74.71

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	40	18	22
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	73.98	76.43	71.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

81.49

22.27

2.0

1.6

—

(3042936) Bacteria identified in Isolate by Culture

13.00

15.46

2.7

2.1

—

(3036670) Protein [Mass/volume] in Synovial fluid

+∞

12.06

1.4

0.0

47.00

—

g/l

—

(3023368) Bacteria identified in Blood by Culture

11.14

10.80

4.8

—

(3019225) pH of Specimen

12.57

10.61

7.3

3.6

—

(3026493) Urate [Moles/volume] in Serum or Plasma

8.65

10.21

2.6

2.7

332.15

16247.68

umol/l

1.07

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

7.70

9.44

5.6

5.4

33.70

32.89

—

(3013512) EKG study

116

6.45

7.19

5.2

4.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

5.59

6.82

2.7

2.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

14.58

6.79

2.6

2.7

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

14.58

6.79

1.7

1.8

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

16.09

6.49

1.4

2.0

—

(3044640) Blood type and Crossmatch panel - Blood

104

5.29

6.18

3.3

2.5

—

(3022217) INR in Platelet poor plasma by Coagulation assay

180

6.90

5.91

32.6

12.4

1.56

1.19

inr

—

(3019309) Folate [Moles/volume] in Red Blood Cells

4.33

4.92

2.3

1.6

1127.08

1296.25

nmol/l

0.32

(3018010) Neutrophils/100 leukocytes in Blood

164

4.94

4.80

10.1

5.9

60.16

58.74

0.26

156

(3015377) Calcium [Moles/volume] in Serum or Plasma

115

4.13

4.56

2.7

3.9

2.36

2.35

mmol/l

0.12

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

5.88

4.38

4.3

2.6

0.26

1.58

mmol/l

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

5.88

4.38

4.3

2.7

4.80

4.89

kpa

0.17

(40760892) CBC W Ordered Manual Differential panel - Blood

160

4.50

4.37

13.2

6.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

143

4.19

4.32

3.6

2.5

—

(3022313) Gas panel - Capillary blood

6.63

4.15

4.3

2.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

164

4.32

4.13

7.8

6.2

1.23

1.20

mmol/l

1.09

136

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

4.11

4.10

2.5

1.9

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

10.28

3.94

1.1

1.3

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

13.75

3.89

1.3

1.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

4.04

3.87

6.3

8.1

—

(3004616) Nuclear Ab [Presence] in Serum

11.45

3.62

1.5

1.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

9.80

3.38

1.7

1.1

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

9.80

3.38

1.5

1.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

4.97

3.36

2.7

2.0

—

(3025159) Blasts/100 leukocytes in Blood

4.97

3.36

4.9

3.4

0.00

1.29

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

117

3.27

3.30

3.9

3.4

1797.06

1560.33

ng/l

0.11

100

(3021440) Promyelocytes/100 leukocytes in Blood

4.77

3.25

5.0

3.4

0.00

0.14

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

8.56

3.17

1.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

146

3.23

3.10

2.3

2.0

112.90

94.92

pmol/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

155

3.28

3.10

2.6

2.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

248

4.28

3.05

13.9

8.4

79.60

76.56

u/l

0.19

228

(3017181) Myelocytes/100 leukocytes in Blood

4.40

3.04

5.0

3.3

0.20

0.89

—

(3037467) Urinalysis macro (dipstick) panel - Urine

235

3.97

2.99

8.6

4.2

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

7.60

2.98

1.7

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

7.60

2.98

2.5

2.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

226

3.62

2.91

7.5

4.4

—

121.67

—

(3023520) Reticulocytes [#/volume] in Blood

3.82

2.85

3.9

2.9

89.64

68.27

e9/l

0.88

(3013290) Carbon dioxide [Partial pressure] in Blood

9.28

2.83

1.4

4.0

4.30

5.03

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

9.28

2.83

1.4

4.0

7.46

8.08

kpa

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

125

2.98

2.82

3.2

2.2

89.59

73.62

nmol/l

1.08

104

(40760888) Immunoglobulin light chains.free panel - Serum

6.82

2.80

2.0

2.2

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

6.82

2.80

1.5

1.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

111

2.88

2.68

2.5

2.1

93.76

165.10

u/l

1.74

103

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.75

2.48

1.6

1.8

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

236

3.27

2.46

4.8

3.8

15.26

15.05

pmol/l

0.18

205

(3007164) IgA [Mass/volume] in Serum or Plasma

3.07

2.37

1.5

1.3

1.87

2.61

g/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

5.22

2.36

1.3

1.7

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

181

2.82

2.32

5.8

6.9

10.89

10.25

umol/l

0.17

171

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

6.16

2.28

2.4

1.6

—

(3044889) 12 lead EKG panel

235

0.38

2.19

5.6

4.1

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

4.21

2.02

1.0

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

3.02

1.95

3.2

5.7

282.78

253.11

u/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

3.31

1.82

1.0

1.6

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

3.52

1.73

2.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.04

1.67

1.0

1.8

—

(3022145) Colonoscopy Study observation

2.76

1.58

1.0

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

100

2.22

1.56

1.9

1.7

23.54

22.23

nmol/l

—

(3025941) Bacteria identified in Stool by Culture

3.41

1.48

1.2

1.3

—

(4200892) Spirometry reversibility

2.71

1.47

1.3

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

0.00

1.42

0.0

6.7

—

118.55

—

(40761535) Cells panel - Urine sediment

2.60

1.36

4.0

3.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.02

1.32

1.4

5.4

21.96

25.05

mmol/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

291

2.62

1.25

6.3

4.7

2.56

2.07

mu/l

0.58

251

(40768797) Stomach Pathology biopsy report

2.28

1.24

1.5

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.18

1.16

2.0

1.8

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.00

1.01

0.0

6.9

—

0.78

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.00

1.01

0.0

7.0

—

1.49

—

(3002582) Erythrocytes [#/volume] in Urine

122

0.48

0.99

2.4

2.5

15.29

567.20

e6/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.25

0.94

1.8

1.3

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

302

2.27

0.94

7.0

6.6

40.93

41.19

mmol/mol

0.06

274

(3030981) Hyaline casts [#/volume] in Urine by Automated count

0.00

0.82

0.0

3.1

—

0.04

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

0.00

0.80

0.0

6.4

—

24.53

—

(3026008) Bacteria identified in Urine by Culture

122

1.68

0.77

2.8

3.2

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

103

0.51

0.75

1.8

2.7

29.33

29.75

u/l

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

142

1.64

0.74

6.8

5.4

2.81

2.30

ug/l

0.23

126

(3021589) Normoblasts [#/volume] in Blood

144

0.59

0.65

32.0

12.3

0.00

e9/l

—

122

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.62

0.0

3.5

—

25.22

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.62

0.0

3.1

—

3.95

—

(3020891) Body temperature

0.00

0.62

0.0

3.7

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.62

0.0

3.4

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.62

0.0

3.0

—

127.33

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

305

1.76

0.62

5.0

4.3

1.23

1.29

mmol/l

0.23

268

(40761536) Microorganisms panel - Urine sediment

1.84

0.61

4.8

3.7

—

(36304419) Bacteria [Presence] in Urine

106

0.59

2.4

2.3

—

(3030467) Casts [#/volume] in Urine by Automated count

109

0.57

0.59

2.4

2.3

1.89

0.12

e6/l

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

145

0.67

0.45

4.6

3.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.59

0.43

1.2

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.54

0.42

6.8

4.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.54

0.42

1.0

1.7

—

(3002256) Pathology report gross observation

1.54

0.42

1.0

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.42

0.0

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.00

0.41

0.0

2.4

—

0.96

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.00

0.41

0.0

2.4

—

0.70

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

325

1.61

0.40

5.4

5.5

2.58

mmol/l

0.00

285

(3000850) Epithelial cells [#/volume] in Urine

0.63

0.38

2.5

2.2

1.73

2.96

e6/l

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

315

1.53

0.38

6.3

4.9

1.42

1.44

mmol/l

0.09

277

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

315

1.53

0.38

5.3

4.9

4.32

4.43

mmol/l

0.20

284

(3009261) Glucose [Presence] in Urine by Test strip

179

0.74

0.32

3.7

0.00

estimate

—

(3012516) Albumin [Mass/volume] in Urine

105

1.35

0.30

3.8

3.0

52.92

56.55

mg/l

—

(3035350) Ketones [Presence] in Urine by Test strip

177

0.76

0.29

3.9

3.7

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

177

0.76

0.29

5.1

4.8

0.00

estimate

—

(3020682) Albumin/Creatinine [Ratio] in Urine

117

1.30

0.25

4.5

3.5

9.10

8.03

mg/mmol

—

(3009508) Creatinine [Moles/volume] in Urine

108

1.30

0.24

3.8

2.9

6.66

7.28

mmol/l

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.32

0.24

1.0

1.7

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

4.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.21

0.0

3.8

—

6.54

—

(1002224) Polysomnography panel

0.00

0.21

0.0

1.3

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.21

0.0

3.8

—

1.35

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

0.00

0.21

0.0

5.1

—

0.87

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

5.3

—

175.57

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

5.0

—

86.60

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.21

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.21

0.0

1.3

—

(1761868) Lipid panel - Serum or Plasma

100

1.29

0.21

3.1

3.6

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

0.00

0.21

0.0

7.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(40758558) Short blood count panel - Blood

0.79

0.16

10.0

8.0

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

312

1.33

0.16

6.3

5.3

5.88

6.06

mmol/l

0.28

275

(40768804) Tissue Pathology biopsy report

143

0.87

0.09

2.5

2.1

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.11

0.09

2.3

3.4

2.48

2.45

mmol/l

—

(3026782) Osmolality of Urine

0.82

0.08

2.7

429.67

543.86

mosm/kgh2o

—

(3003694) ABO and Rh group [Type] in Blood

1.14

0.08

1.1

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

101

0.86

0.07

4.1

3.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

143

1.08

0.02

4.4

2.5

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.0

—

13.40

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

1.4

—

37.44

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.2

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.2

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

334.20

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.6

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

2.2

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

2.4

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.0

3.0

—

(3047181) Lactate [Moles/volume] in Blood

0.00

-0.00

0.0

7.6

—

1.23

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

-0.00

0.0

2.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

107.22

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

-0.00

0.0

1.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

4.07

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

-0.00

0.0

1.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.8

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

-0.00

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

2.2

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.1

—

(4034850) Laboratory test

0.00

-0.00

0.0

6.1

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.2

—

187.27

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

481.14

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint FAMIL_CHONDROCALC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have FAMIL_CHONDROCALC.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: FAMIL_CHONDROCALC – Familial chondrocalcinosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Familial chondrocalcinosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints