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Malignant neoplasm of other and unspecified male genital organs, including Hilmo

C3_MALE_GENITAL_NAS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only males

226754

2. Check conditions

None

226754

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C63
  • Hospital discharge: ICD-9 187
  • Hospital discharge: ICD-8 187
  • Cause of death: ICD-10 C63
  • Cause of death: ICD-9 187
  • Cause of death: ICD-8 187
  • Cause of death: excluded ICD-9 187[1-4]
  • Cause of death: excluded ICD-8 1870
  • Cancer registry: Topography ICD-O-3 C63
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

63

4. Check minimum number of events

None

63

5. Include endpoints

None

63

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 61 - 61
Unadjusted period prevalence (%) 0.03 - 0.03
Median age at first event (years) 65.24 - 65.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
63
Matched controls
630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
19.8
18
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
17.5
16
*
130
Kela drug reimbursment
Malignant tumour
+∞
17.5
16
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
227.9
17.4
17
*
C63.2
ICD-10 Finland
Malignant neoplasm: Scrotum
+∞
10.7
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.7
10
*
C63.0
ICD-10 Finland
Malignant neoplasm: Epididymis
+∞
9.6
9
*
C63.9
ICD-10 Finland
Malignant neoplasm: Male genital organ, unspecified
+∞
9.6
9
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.3
9.2
26
74
H02AB02
ATC
dexamethasone; systemic
58.4
9.0
10
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
+∞
8.5
8
*
N02AA05
ATC
oxycodone; systemic
5.8
8.4
19
44
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
90.3
7.6
8
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
7.4
7
*
L02BB03
ATC
bicalutamide; oral
+∞
7.4
7
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
14.5
6.9
11
9
Z51.5
ICD-10 Finland
Palliative care
16.6
6.6
10
7
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
77.4
6.6
7
*
B01AB10
ATC
tinzaparin; parenteral
10.3
6.4
12
14
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
88
4.62
7.92
2.8
1.4
—
—
—
0
0
17
26
8.53
7.79
1.2
1.0
—
—
—
0
0
13
12
13.28
7.72
1.7
1.2
—
—
—
0
0
29
126
3.41
5.31
4.0
2.3
—
—
—
0
0
21
75
3.70
5.17
2.1
2.3
—
—
—
0
0
24
103
3.15
4.35
4.0
2.8
—
—
—
0
0
29
139
3.01
4.34
8.7
4.4
—
—
—
0
0
17
60
3.51
4.19
2.3
1.9
—
—
—
0
0
37
212
2.81
3.87
11.8
3.8
12.75
13.27
umol/l
0.11
37
200
10
21
5.45
3.74
27.2
35.0
—
—
—
0
0
9
18
5.64
3.52
3.3
1.7
—
—
—
0
0
22
101
2.81
3.44
9.6
4.6
—
—
—
0
0
24
116
2.73
3.41
5.0
2.5
0.96
0.41
e6/l
0.26
18
86
13
44
3.46
3.36
23.2
12.3
—
—
—
0
0
20
93
2.69
3.02
3.1
3.4
—
—
—
0
0
22
108
2.59
2.98
5.1
2.3
—
—
—
0
0
12
44
3.13
2.72
24.8
23.1
112.83
123.59
g/l
1.11
12
44
32
194
2.32
2.70
19.0
9.0
1.17
1.20
mmol/l
1.12
32
172
24
130
2.37
2.60
5.7
2.6
222.19
120.06
e6/l
0.20
18
101
14
58
2.82
2.59
2.6
1.6
1.74
1.49
%
0.79
14
47
14
58
2.82
2.59
21.9
18.3
0.39
1.33
mmol/l
0.37
14
46
37
242
2.28
2.57
25.5
18.8
1.58
1.41
inr
—
10
59
26
147
2.31
2.55
6.9
3.0
1427.83
21.30
e6/l
0.52
20
105
32
199
2.24
2.49
9.5
4.8
—
—
—
0
0
6
12
5.40
2.46
1.0
1.1
—
—
—
0
0
14
60
2.71
2.42
3.4
3.0
21.49
24.59
%
0.60
14
52
14
62
2.62
2.27
3.1
2.8
2.11
2.19
g/l
0.21
14
56
37
251
2.15
2.25
15.9
5.5
4.58
4.56
e9/l
0.01
32
219
39
280
2.03
1.93
12.3
6.5
6.92
6.97
mmol/l
0.05
39
264
9
36
2.74
1.82
1.6
1.3
57.97
65.26
g/l
—
9
28
32
219
1.94
1.77
9.2
4.8
0.63
0.63
e9/l
0.05
25
192
32
220
1.92
1.74
9.2
4.7
0.04
0.04
e9/l
0.20
24
194
32
222
1.90
1.68
10.0
5.0
2.60
1.79
e9/l
0.45
26
197
39
289
1.92
1.67
5.1
3.4
—
—
—
0
0
7
26
2.90
1.63
2.6
2.5
—
—
—
0
0
14
73
2.18
1.59
3.5
2.6
11.22
13.86
umol/l
1.09
14
64
13
66
2.22
1.57
23.3
9.0
103.38
104.79
mmol/l
0.41
13
66
28
190
1.85
1.54
16.7
8.0
0.00
0.00
e9/l
-0.00
20
153
32
228
1.82
1.50
11.3
4.9
0.19
0.21
e9/l
0.30
25
197
24
157
1.85
1.47
3.5
2.6
274.60
175.66
ug/l
0.38
24
143
5
16
3.30
1.46
19.0
3.1
—
—
—
0
0
43
337
1.87
1.46
13.4
5.2
80.49
73.75
u/l
0.78
43
310
5
17
3.10
1.38
2.4
1.5
22.80
20.88
s
—
5
17
5
17
3.10
1.38
1.0
1.2
—
—
—
0
0
9
43
2.27
1.37
1.4
2.0
—
—
—
0
0
16
96
1.89
1.25
6.9
3.5
48.31
150.50
ng/l
0.76
16
84
7
30
2.50
1.16
1.0
1.4
—
—
—
0
0
5
21
2.50
1.11
6.4
25.4
0.92
0.87
%
—
5
21
8
144
0.49
1.11
3.3
3.6
—
—
—
0
0
9
47
2.06
1.08
1.1
1.4
—
—
—
0
0
5
22
2.38
1.05
1.6
1.1
—
—
—
0
0
44
365
1.68
1.05
42.7
15.8
14.97
14.57
%
0.20
44
358
40
326
1.62
1.00
4.7
4.1
—
—
—
0
0
7
37
2.00
0.97
5.1
17.1
—
—
—
0
0
6
31
2.03
0.87
5.8
5.2
78.82
110.60
ng/l
—
6
25
0
26
0.00
0.80
0.0
3.7
—
4.45
—
0
18
17
118
1.60
0.80
2.7
1.8
3.10
2.75
mg/l
0.33
17
97
5
23
2.27
0.78
6.4
23.6
1.92
1.45
%
—
5
23
9
55
1.74
0.78
1.8
1.7
—
—
—
0
0
7
38
1.95
0.76
1.0
1.3
—
—
—
0
0
9
57
1.67
0.75
5.0
3.4
5.63
5.84
kpa
—
9
52
9
57
1.67
0.75
5.0
3.4
-2.13
1.55
mmol/l
—
9
43
7
40
1.84
0.74
1.6
1.3
—
—
—
0
0
7
42
1.75
0.71
1.6
1.5
—
—
—
0
0
14
96
1.59
0.69
1.1
1.2
—
—
—
0
0
5
28
1.85
0.67
1.2
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
8
59
1.41
0.43
3.9
3.3
5.01
8.31
ug/l
—
8
51
0
15
0.00
0.42
0.0
1.3
—
—
—
0
0
8
111
0.68
0.42
5.4
2.9
—
—
—
0
0
7
96
0.70
0.34
5.6
3.4
—
1.02
—
0
10
19
223
0.79
0.31
3.9
3.9
45.85
72.91
ng/l
0.67
13
172
41
441
0.80
0.30
5.5
5.4
2.34
2.49
mmol/l
0.59
41
401
21
182
1.23
0.26
2.8
2.5
1.27
0.81
ug/l
0.24
16
122
49
464
1.25
0.24
43.7
18.3
139.69
139.65
mmol/l
0.02
49
449
5
37
1.38
0.24
6.4
3.7
—
—
—
0
0
51
485
1.27
0.24
48.7
20.0
91.47
91.40
fl
0.04
51
473
13
107
1.27
0.24
2.2
1.8
553846488.54
390.59
pmol/l
0.47
13
85
8
103
0.74
0.23
2.9
1.9
1205.53
1258.13
nmol/l
—
8
79
49
465
1.24
0.23
44.7
18.3
4.01
4.04
mmol/l
0.39
49
449
51
486
1.26
0.23
48.7
19.9
30.24
30.61
pg
0.69
51
474
51
486
1.26
0.23
49.1
20.1
129.08
140.00
g/l
3.14
51
475
5
42
1.21
0.22
3.2
3.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
6
47
1.31
0.21
1.2
1.3
—
310.77
—
0
13
6
48
1.28
0.21
6.3
2.5
4.97
4.25
kpa
—
6
43
41
431
0.86
0.16
4.7
4.8
6.02
6.17
mmol/l
0.55
41
379
16
142
1.17
0.14
3.2
4.6
—
—
—
0
0
47
455
1.13
0.10
28.9
13.0
—
—
—
0
0
20
201
0.99
0.00
2.5
1.9
92.64
91.86
pmol/l
0.02
11
118
41
412
0.99
0.00
5.9
6.9
40.11
41.44
mmol/mol
0.51
41
378
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
332.80
—
0
5
0
5
0.00
-0.00
0.0
4.6
—
0.10
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
4.19
—
0
9
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
142.09
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
105.33
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.5
—
12.98
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_MALE_GENITAL_NAS_WIDE – Malignant neoplasm of other and unspecified male genital organs, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).