conjunctival scars

H7_CONJUNCTSCAR

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H11.2 Hospital discharge: ICD-9 — 3726 Hospital discharge: ICD-8 — 37821 Cause of death: ICD-10 — H11.2 Cause of death: ICD-9 — 3726 Cause of death: ICD-8 — 37821 2 out of 7 registries used, show all original rules.	57
4. Check minimum number of events None	57
5. Include endpoints None	57
6. Filter based on genotype QC (FinnGen only)	57

Control definitions (FinnGen only)

Control exclude: H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H11
Name in latin: Cicatrix/cicatrices conjunctivae

NAME	H7_CONJUNCTSCAR
CONTROL_EXCLUDE	H7_CONJUNCTIVA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H112
HD_ICD_9	3726
HD_ICD_8	37821
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H112
COD_ICD_9	3726
COD_ICD_8	37821
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to conjunctival scars based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	517	276	238
Only index persons	461	254	207
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	51.16	50.27	52.30
Only index persons	50.33	48.96	52.02

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	57	37	20
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	48.77	48.20	49.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
53: Matched controls
531

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H11.2

ICD-10 Finland

Conjunctival scars

+∞

62.4

CFD10

NOMESCO Finland

Repair of conjunctiva

+∞

9.7

CFC00

NOMESCO Finland

Excision of lesion of conjunctiva

+∞

8.6

H04.10

ICD-10 Finland

Dry eye syndrome

10.5

7.8

S01XA20

ATC

artificial tears and other indifferent preparations; ophthalmic

4.9

7.0

134

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

4.4

6.1

114

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

4.62

5.86

2.1

1.4

—

(3032080) INR in Blood by Coagulation assay

155

3.19

4.45

6.5

6.8

1.4

1.1

inr

—

(3022145) Colonoscopy Study observation

3.29

3.06

1.1

1.3

—

(3007566) Smooth muscle Ab [Titer] in Serum

5.36

2.11

1.4

—

(3034770) Mitochondria Ab [Titer] in Serum

5.36

2.11

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

2.00

0.0

1.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

104

2.24

1.98

2.2

2.1

—

(40768804) Tissue Pathology biopsy report

181

2.08

1.91

2.2

1.9

—

(3042936) Bacteria identified in Isolate by Culture

2.47

1.89

2.2

2.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

441

3.04

1.78

16.3

12.8

39.4

40.5

0.37

342

(3044640) Blood type and Crossmatch panel - Blood

142

2.04

1.75

3.2

2.1

—

(42870588) Differential panel, method unspecified - Blood

148

1.93

1.52

6.2

5.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

211

1.89

1.52

4.1

3.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.15

1.50

2.4

3.2

26.0

24.4

ng/l

—

(3023368) Bacteria identified in Blood by Culture

109

1.95

1.40

3.4

4.5

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

1.40

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.42

1.30

2.4

3.1

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.64

1.17

2.2

2.0

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

2.51

1.11

6.0

2.5

23.9

24.2

mmol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.20

1.07

1.4

1.8

—

(3025159) Blasts/100 leukocytes in Blood

2.20

1.07

5.7

5.0

—

0.0

—

(3002179) Metamyelocytes/100 leukocytes in Blood

2.14

1.04

5.7

5.1

—

0.4

—

(4035726)

1.95

1.02

1.3

—

(3000330) Specific gravity of Urine by Test strip

2.36

0.97

5.3

4.0

—

(3019309) Folate [Moles/volume] in Red Blood Cells

1.82

0.90

1.4

1.7

1171.0

1070.5

nmol/l

—

(3019060) Gas panel - Arterial blood

2.11

0.90

1.3

4.2

—

(40768797) Stomach Pathology biopsy report

1.75

0.78

1.0

1.2

—

(3017181) Myelocytes/100 leukocytes in Blood

1.90

0.76

5.7

4.7

—

0.9

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.78

0.74

1.6

1.5

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

2.01

0.72

3.8

2.6

136.2

129.7

g/l

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

123

1.54

0.68

1.8

1.6

1.4

1.3

mmol/l

0.17

102

(3013512) EKG study

126

1.50

0.61

4.8

3.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

309

1.45

0.61

3.4

3.2

—

(3000492) Spirometry study

1.80

0.60

1.5

1.7

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.59

0.0

2.9

—

(3021440) Promyelocytes/100 leukocytes in Blood

1.69

0.57

2.7

4.9

—

0.3

—

(3012544) pH of Venous blood

1.60

0.55

5.5

3.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

441

1.56

0.50

3.9

3.6

1.4

1.3

mmol/l

0.38

407

(3002256) Pathology report gross observation

1.53

0.45

1.5

1.2

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.50

0.45

1.6

3.6

0.8

mmol/l

—

(40761536) Microorganisms panel - Urine sediment

1.67

0.44

5.8

2.6

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

269

1.33

0.43

3.5

4.2

6.5

6.4

mmol/l

0.07

239

(3024354) Oxygen [Partial pressure] in Venous blood

1.56

0.42

4.0

2.7

4.1

4.2

kpa

—

(3044889) 12 lead EKG panel

310

1.33

0.42

4.3

3.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.42

0.0

2.1

—

(4034850)

0.00

0.42

0.0

8.1

—

(40768793) Breast Pathology biopsy report

0.00

0.42

0.0

1.3

—

(36660697) Celiac disease serology panel - Serum

1.51

0.41

1.4

1.1

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.41

0.0

1.7

—

5.4

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.9

—

4.3

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.8

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.9

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.9

—

8.8

—

(3037467) Urinalysis macro (dipstick) panel - Urine

321

1.33

0.41

6.4

4.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.40

0.0

1.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.40

0.0

1.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.40

0.0

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.44

0.40

1.5

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

155

1.34

0.39

4.6

3.4

19.1

47.6

ng/l

0.57

107

(3009508) Creatinine [Moles/volume] in Urine

127

1.36

0.39

2.7

2.8

6.5

8.3

mmol/l

0.81

101

(3011397) Hemoglobin [Presence] in Urine by Test strip

109

1.38

0.38

2.7

3.5

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.48

0.37

5.5

3.0

5.9

5.8

kpa

—

(1761868) Lipid panel - Serum or Plasma

174

0.74

0.36

3.7

2.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.44

0.36

1.2

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.41

0.36

1.2

1.6

—

(3021601) Nitrite [Presence] in Urine by Test strip

225

1.29

0.35

7.4

4.9

0.0

estimate

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

177

1.30

0.34

5.0

3.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

440

1.39

0.34

15.8

12.1

81.9

82.0

ml/min/173m2

0.02

351

(40758558) Short blood count panel - Blood

112

1.33

0.32

4.2

8.7

—

(36304419) Bacteria [Presence] in Urine

128

0.73

0.31

2.0

2.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

1.36

0.31

2.0

1.4

2.9

2.4

g/l

—

(3009261) Glucose [Presence] in Urine by Test strip

228

1.26

0.31

4.8

3.5

0.0

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

223

1.22

0.24

4.8

3.4

0.0

estimate

—

(3022621) pH of Urine by Test strip

1.31

0.23

4.0

2.6

—

(3012516) Albumin [Mass/volume] in Urine

117

1.26

0.23

2.9

3.1

45.2

49.7

mg/l

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

2.2

—

0.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.21

0.0

3.1

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

2.2

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.5

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

129

1.22

0.19

5.5

2.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

450

1.25

0.19

4.7

3.9

5.8

5.7

mmol/l

0.09

417

(21494755) Public health laboratory ask at order entry panel

1.17

0.18

1.4

1.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

161

0.83

0.18

2.4

3.0

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

358

1.18

0.18

9.4

7.7

85.0

78.8

u/l

0.44

330

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.20

0.17

1.6

1.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

121

1.21

0.17

3.6

3.7

6.8

7.2

mg/mmol

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.23

0.16

1.7

1.9

—

(3026782) Osmolality of Urine

1.12

0.16

4.3

2.6

553.7

569.5

mosm/kgh2o

—

(3003694) ABO and Rh group [Type] in Blood

132

1.19

0.15

1.3

1.5

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

465

1.20

0.14

4.7

4.0

4.9

4.7

mmol/l

0.65

431

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

462

1.25

0.14

4.8

4.0

1.5

mmol/l

0.00

428

(3015736) pH of Urine

173

1.15

0.12

3.9

3.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.20

0.12

1.3

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

106

1.17

0.11

5.6

5.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.15

0.10

1.2

1.4

—

(3026008) Bacteria identified in Urine by Culture

134

0.87

0.10

4.8

3.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

1.17

0.10

1.4

1.2

—

0.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.80

0.09

1.6

—

(3000850) Epithelial cells [#/volume] in Urine

0.87

0.07

2.3

2.2

8.4

3.9

e6/l

—

(3018095) Leukocytes [#/volume] in Urine

161

0.91

0.06

2.8

3.7

121.5

40.1

e6/l

—

113

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

169

1.10

0.06

1.5

1.9

88.5

92.3

pmol/l

0.15

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

430

1.10

0.05

6.3

5.0

39.2

38.9

mmol/mol

0.10

403

(3029937) Albumin [Presence] in Urine by Test strip

117

0.93

0.02

4.5

3.6

0.0

estimate

—

(3031040) Bacteria [#/volume] in Urine by Automated count

303

0.98

0.00

4.5

4.0

—

45.0

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

146

1.04

0.00

2.5

2.4

40.5

54.4

u/l

1.28

135

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(4268621)

0.00

0.0

2.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

3.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

2.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.7

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.3

—

(4306422)

0.00

0.0

1.0

—

(3000494) Fungus identified in Specimen by Culture

0.90

0.00

1.2

1.4

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

2.1

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

2.4

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.7

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

475

1.07

0.00

5.0

4.4

2.9

2.8

mmol/l

0.29

442

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.9

—

17.0

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

0.90

0.00

3.9

3.3

2.5

2.4

mmol/l

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.0

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.0

3.4

—

5.3

—

(3014037) CD3+CD4+ (T4 helper) cells/100 cells in Blood

0.00

0.0

2.6

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

2.1

—

0.4

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

15.5

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.0

3.4

—

63.4

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

59.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.85

0.00

1.4

1.8

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.94

0.00

1.2

1.7

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.00

0.00

5.5

6.4

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

99.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.96

0.00

1.4

1.7

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

2.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.3

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CONJUNCTSCAR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUNCTSCAR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_CONJUNCTSCAR – conjunctival scars

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

conjunctival scars

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints