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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Ribs, sternum and clavicle

CD2_BENIGN_RIBS_STERNUM_CLAVICLE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.7&
  • Hospital discharge: ICD-9 2133
  • Hospital discharge: ICD-8 21302
  • Cause of death: ICD-10 D16.7&
  • Cause of death: ICD-9 2133
  • Cause of death: ICD-8 21302

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D16
Name in latin
Neoplasma benignum costae, sterni sive claviculae

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 82 42 40
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 41.50 45.12 37.70

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
79
Matched controls
790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.7
ICD-10 Finland
Benign neoplasm: Ribs, sternum and clavicle
+∞
51.9
44
*
21302
ICD-8 Finland
Benign neoplasm of bone and cartilage, Costae, sterni, claviculae
+∞
26.5
24
*
2133A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle
+∞
11.7
11
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
7.4
7
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
29.3
6.4
8
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.0
6.0
13
19

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
78
2.49
2.52
1.1
2.8
—
—
—
0
0
50
365
1.95
2.21
8.4
6.3
3.5
4.2
e9/l
1.64
43
317
31
194
1.96
2.14
2.1
1.5
—
—
—
0
0
11
45
2.67
2.03
1.5
1.3
—
—
—
0
0
6
17
3.72
1.87
1.5
1.9
16.5
19.9
u/ml
—
6
17
21
120
2.01
1.85
1.3
1.3
22.2
10.6
u/ml
—
7
43
27
169
1.89
1.83
1.8
2.3
294.8
2613.8
umol/l
0.51
22
143
27
170
1.88
1.80
2.3
2.2
—
—
—
0
0
6
18
3.51
1.78
1.2
1.2
—
—
—
0
0
35
240
1.80
1.77
4.5
8.3
1.1
1.3
inr
—
6
66
28
181
1.83
1.71
2.5
2.9
—
—
—
0
0
21
126
1.90
1.60
1.4
1.3
9.1
40.4
iu/ml
—
8
44
9
40
2.40
1.45
1.0
1.1
—
—
—
0
0
31
219
1.67
1.35
8.2
5.1
—
—
—
0
0
5
18
2.89
1.30
1.8
1.2
—
—
—
0
0
23
157
1.65
1.12
1.2
1.3
0.9
1.2
u/ml
—
5
34
9
45
2.12
1.09
4.1
10.7
—
—
—
0
0
13
76
1.84
1.06
2.5
2.5
2.8
2.4
g/l
2.29
13
71
34
261
1.52
1.00
3.3
3.8
35.8
36.3
g/l
0.24
26
244
47
387
1.50
0.99
3.2
5.0
6.6
6.6
mmol/l
0.02
40
357
48
402
1.47
0.90
5.5
3.9
—
39.4
—
0
5
11
65
1.80
0.87
1.1
1.1
—
—
—
0
0
6
32
1.94
0.83
1.7
1.4
—
—
—
0
0
11
66
1.77
0.83
3.8
2.9
—
—
—
0
0
8
47
1.78
0.83
2.4
3.2
124.3
124.0
ng/l
—
8
42
6
33
1.88
0.81
5.7
11.2
0.9
0.9
%
—
6
33
59
520
1.48
0.81
4.4
4.0
15.1
14.7
pmol/l
0.66
49
471
6
34
1.82
0.78
5.7
11.0
2.2
2.1
%
—
6
34
39
460
0.71
0.76
4.9
3.8
—
—
—
0
0
19
254
0.67
0.74
2.4
3.2
—
—
—
0
0
5
28
1.84
0.67
2.2
2.8
—
—
—
0
0
14
96
1.55
0.67
1.6
1.2
—
—
—
0
0
58
521
1.39
0.62
5.6
3.9
11.3
11.4
mm/h
0.00
52
471
9
62
1.51
0.55
1.2
1.7
—
—
—
0
0
11
77
1.49
0.48
1.5
1.2
—
—
—
0
0
7
48
1.50
0.48
1.1
1.2
—
—
—
0
0
7
49
1.47
0.47
1.3
2.1
0.2
0.2
g/l
—
7
44
71
671
1.43
0.45
15.6
11.7
20.2
19.9
mg/l
0.02
53
495
59
632
0.76
0.44
6.3
6.2
40.1
40.3
mmol/mol
0.08
53
589
8
58
1.42
0.43
1.3
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
3.7
—
38.4
—
0
8
5
35
1.46
0.40
2.2
1.8
—
—
—
0
0
48
435
1.25
0.39
5.0
4.0
—
—
—
0
0
20
163
1.30
0.39
4.3
2.8
—
—
—
0
0
15
118
1.33
0.37
3.1
2.6
0.5
0.8
ug/l
—
8
68
66
623
1.30
0.36
5.5
4.8
2.0
1.9
mu/l
0.39
56
566
6
45
1.36
0.34
3.2
4.3
—
—
—
0
0
25
214
1.24
0.33
3.0
3.8
1.5
8.6
mg/mmol
2.31
17
139
17
139
1.28
0.32
3.6
4.4
—
—
—
0
0
29
254
1.22
0.31
2.3
2.1
101.8
99.6
pmol/l
0.10
15
127
24
208
1.22
0.28
3.0
4.1
—
—
—
0
0
23
199
1.22
0.27
2.7
3.1
11.6
57.5
mg/l
2.06
16
130
17
143
1.24
0.26
4.4
3.1
—
—
—
0
0
18
153
1.23
0.25
4.6
4.5
—
—
—
0
0
27
240
1.19
0.24
3.9
3.3
—
—
—
0
0
20
173
1.21
0.24
4.3
2.9
0.4
0.2
e6/l
0.29
15
125
5
39
1.30
0.23
2.4
14.9
—
—
—
0
0
17
145
1.22
0.23
1.2
1.3
3.1
2.6
g/l
—
9
77
11
89
1.27
0.22
3.0
2.4
12.2
13.5
umol/l
0.32
11
82
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
90.3
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
6
47
1.30
0.21
4.0
2.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
106.0
—
0
14
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
4.1
—
0
14
26
286
0.87
0.19
10.2
8.4
0.0
0.0
e9/l
0.00
21
230
62
640
0.87
0.15
3.8
4.3
1.3
1.3
mmol/l
0.09
54
589
16
177
0.88
0.11
3.1
3.7
—
—
—
0
0
21
194
1.11
0.10
4.3
2.9
758.5
365.9
e6/l
0.20
15
147
13
143
0.89
0.08
1.5
1.4
—
—
—
0
0
67
660
1.08
0.04
4.0
4.7
4.8
4.7
mmol/l
0.68
59
616
10
91
1.11
0.04
3.6
3.0
0.9
0.8
mmol/l
—
10
84
33
322
1.04
0.02
3.9
3.6
0.0
0.0
estimate
—
5
47
15
143
1.06
0.01
4.3
3.7
—
1.0
—
0
23
66
653
1.05
0.01
5.2
4.5
6.0
6.0
mmol/l
0.01
59
598
32
313
1.04
0.01
4.0
3.6
0.0
0.0
estimate
—
5
50
70
694
1.06
0.01
16.7
10.6
—
—
—
0
0
15
153
0.98
0.00
5.5
5.5
—
—
—
0
0
28
283
0.98
0.00
3.7
3.6
18.6
56.0
ng/l
1.74
17
187
66
655
1.04
0.00
4.1
4.7
1.6
1.5
mmol/l
0.84
58
607
67
674
0.97
0.00
4.5
5.2
2.9
2.8
mmol/l
0.37
60
623
22
224
0.98
0.00
5.4
3.3
99.8
118.1
e6/l
0.09
17
151
61
606
1.03
0.00
18.0
13.5
40.9
40.5
%
0.20
44
436
6
61
0.98
0.00
1.7
1.4
—
—
—
0
0
7
72
0.97
0.00
1.9
5.0
1.1
1.0
mmol/l
—
7
65
5
52
0.96
0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
33.8
—
0
5
0
6
0.00
0.00
0.0
3.0
—
2.0
—
0
6
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.98
0.00
1.3
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
1965.8
—
0
6
0
7
0.00
0.00
0.0
1.3
—
105.3
—
0
7
6
64
0.93
0.00
1.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
11.9
—
0
6
0
5
0.00
0.00
0.0
1.4
—
138.0
—
0
5
0
5
0.00
0.00
0.0
1.6
—
1.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
11.6
—
0
5
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
7
79
0.88
0.00
1.3
1.7
—
—
—
0
0
7
70
1.00
0.00
1.6
4.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
9
94
0.95
0.00
1.2
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
5.8
1.8
8.8
10.9
g/l
—
5
46
0
5
0.00
0.00
0.0
2.8
—
26.6
—
0
5
0
7
0.00
0.00
0.0
1.1
—
279.4
—
0
7
0
5
0.00
0.00
0.0
2.4
—
115.6
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_RIBS_STERNUM_CLAVICLE_EXALLC – Benign neoplasm: Ribs, sternum and clavicle

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).