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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of skin of lip

DOID Endpoint Browser

CD2_INSITU_SKIN_LIP

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D04.0&
  • Hospital discharge: ICD-9 — 2320
  • Cause of death: ICD-10 — D04.0&
  • Cause of death: ICD-9 — 2320

2 out of 7 registries used, show all original rules.

106

4. Check minimum number of events

None

106

5. Include endpoints

None

106

6. Filter based on genotype QC (FinnGen only)

102

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D04
Name in latin
Carcinoma in situ cutis labii (oris)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 102 39 63
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 73.50 74.16 73.09

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
106
Matched controls
1060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
+∞
152.9
106
*
TQW99
NOMESCO Finland
Other minor procedure on skin
29.6
63.2
50
31
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
22.5
59.4
58
54
L57.0
ICD-10 Finland
Actinic keratosis
19.5
55.7
71
100
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
9.8
29.3
46
77
EAA10
NOMESCO Finland
Excision of lesion of lip
197.0
29.3
29
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
33.5
25.5
33
14
R23.8
ICD-10 Finland
Other and unspecified skin changes
7.7
24.6
52
118
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
37.3
23.9
30
11
ZXC20
NOMESCO Finland
Use of chemical agents
29.3
22.4
30
14
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
37.4
22.3
28
10
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
7.6
20.7
38
73
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.6
20.6
32
51
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
+∞
20.5
19
*
ZQZ00
NOMESCO Finland
Treatment of several skin areas
114.5
18.2
19
*
Z2221
NOMESCO Finland
Medical doctor
5.6
17.8
56
176
EAA30
NOMESCO Finland
Partial excision of lower lip
+∞
16.0
15
*
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
+∞
14.9
14
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
15.1
14.5
24
20
ZZR00
NOMESCO Finland
Flap of skin
24.3
14.4
20
10
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
7.5
14.1
23
38
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
40.0
14.0
17
5
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
14.3
13.1
22
19
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
23.7
13.0
18
9
R4110
NOMESCO Finland
Physiotherapy
4.3
12.4
54
208
D06BB10
ATC
imiquimod; topical
10.2
11.6
23
28
ZXD10
NOMESCO Finland
Scheduled procedure
4.0
11.3
64
291
XF400
NOMESCO Finland
ECG with 12 standard connections
4.1
10.2
38
128
ZXC10
NOMESCO Finland
Use of laser
15.4
10.1
16
12
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
54.7
8.8
10
*
S29
ICPC
Skin symptom/complaint other
3.7
8.8
36
128
Z3231
NOMESCO Finland
Registered nurse
3.4
8.6
51
229
S18
ICPC
Laceration/cut
3.4
8.3
68
369
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
36.4
8.2
10
*
ZXE00
NOMESCO Finland
One hour or less
3.2
7.9
57
284
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
20.2
7.8
11
6
Z3226
NOMESCO Finland
Physiotherapist
3.5
7.6
34
127
8070/3-C44.2
ICD-O-3
Squamous cell carcinoma, NOS, of external ear
+∞
7.4
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.2
7.0
21
59
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
6.9
31
115
D07AB08
ATC
desonide; topical
4.0
6.9
22
65
ZXA05
NOMESCO Finland
Left side
3.0
6.8
45
210
ZXC50
NOMESCO Finland
Cryotherapy
7.7
6.8
15
22
WX002
NOMESCO Finland
Sedation and analgesia
3.1
6.7
38
162
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
6.6
52
267
DHB00
NOMESCO Finland
Excision of lesion of external nose
28.5
6.3
8
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
+∞
6.3
6
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
6.2
18
49
ZXA00
NOMESCO Finland
Right side
2.8
6.2
45
219

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
45
99
7.16
21.63
2.4
1.3
—
—
—
0
0
79
306
7.21
20.36
5.0
2.3
—
—
—
0
0
22
26
10.37
11.23
1.3
1.2
—
—
—
0
0
42
145
4.14
10.98
3.8
2.9
2.69
1.51
e6/l
0.28
25
85
24
72
4.02
7.36
7.0
6.8
—
—
—
0
0
60
322
2.99
7.12
5.0
3.9
47.57
68.97
e6/l
0.30
44
242
23
70
3.92
6.89
1.2
1.4
—
—
—
0
0
48
241
2.81
6.26
4.7
3.1
—
—
—
0
0
54
292
2.73
6.05
4.5
3.2
121.24
303.52
e6/l
0.37
44
230
50
261
2.73
6.00
4.5
3.1
0.65
0.28
e6/l
0.65
39
200
38
172
2.89
5.97
2.5
4.1
—
—
—
0
0
40
199
2.62
5.14
8.3
7.2
—
—
—
0
0
24
91
3.12
5.08
5.2
3.8
5.72
5.68
kpa
0.07
24
86
60
372
2.41
4.70
2.9
2.2
95.54
93.53
pmol/l
0.11
30
185
23
91
2.95
4.50
1.6
1.3
—
—
—
0
0
15
46
3.63
4.38
2.7
2.0
1.76
1.69
g/l
0.11
15
41
20
77
2.97
4.09
2.6
3.1
4.79
4.29
kpa
0.40
20
72
20
78
2.93
4.00
7.0
5.4
12.55
11.08
mmol/l
0.40
20
73
85
645
2.60
3.87
34.4
21.1
14.44
15.58
%
1.89
85
630
17
65
2.92
3.50
1.5
1.6
—
—
—
0
0
76
562
2.24
3.47
5.0
4.4
—
—
—
0
0
76
570
2.18
3.23
5.1
4.2
—
—
—
0
0
8
16
5.31
3.11
2.1
2.4
—
—
—
0
0
20
89
2.54
3.10
2.3
1.6
—
—
—
0
0
7
12
6.16
3.07
2.0
1.8
60.10
66.43
%
—
7
12
5
5
10.40
3.01
1.8
1.2
—
—
—
0
0
27
142
2.21
2.90
2.5
2.6
0.80
0.83
mmol/l
0.87
27
132
57
396
1.95
2.86
8.0
5.4
0.64
0.63
e9/l
0.07
49
338
8
18
4.71
2.85
1.3
1.1
—
—
—
0
0
19
86
2.47
2.84
1.3
2.3
74.37
67.25
e9/l
—
8
70
57
397
1.94
2.83
8.0
5.4
0.03
0.04
e9/l
0.31
48
340
41
258
1.96
2.72
4.3
3.1
102.41
55.66
mg/l
0.28
27
178
23
396
0.46
2.71
4.3
4.3
24.28
51.21
ng/l
1.55
18
320
57
402
1.90
2.68
5.3
3.7
34.51
34.71
g/l
0.08
51
373
53
365
1.90
2.68
7.5
5.8
—
—
—
0
0
29
162
2.09
2.66
3.8
2.2
11.47
12.60
umol/l
0.39
29
146
12
44
2.95
2.65
2.3
2.4
—
—
—
0
0
57
406
1.87
2.57
8.3
5.6
1.87
1.86
e9/l
0.01
49
358
57
407
1.87
2.54
8.2
5.6
0.15
0.19
e9/l
1.29
49
355
51
353
1.86
2.50
10.7
10.5
0.00
0.00
e9/l
0.38
44
297
19
92
2.30
2.45
3.2
2.4
6.19
11.95
umol/l
1.45
19
82
23
122
2.13
2.40
5.9
5.4
1.19
1.32
mmol/l
0.03
17
96
12
47
2.75
2.36
7.4
6.4
—
—
—
0
0
95
821
2.51
2.27
29.8
20.5
98.91
86.36
umol/l
1.09
95
821
37
237
1.86
2.27
3.0
2.1
3.12
3.05
mg/l
0.05
32
210
21
113
2.07
2.10
1.9
1.6
—
—
—
0
0
36
235
1.81
2.06
3.3
2.8
13183.83
8531.28
umol/l
0.14
29
191
11
45
2.61
2.00
1.6
1.7
—
—
—
0
0
17
299
0.49
2.00
4.4
4.5
—
—
—
0
0
39
264
1.76
1.96
3.4
2.3
—
—
—
0
0
11
46
2.55
1.92
1.6
1.5
—
—
—
0
0
60
461
1.69
1.89
11.6
8.6
4.59
4.46
e9/l
0.16
54
399
40
281
1.68
1.73
4.9
3.7
22.53
8.87
mg/mmol
0.41
25
189
94
832
2.15
1.72
30.0
20.0
138.83
139.59
mmol/l
1.78
94
806
94
834
2.12
1.68
30.7
20.0
3.97
4.02
mmol/l
0.98
94
808
10
42
2.52
1.67
1.0
1.4
—
—
—
0
0
9
38
2.49
1.50
1.1
2.9
52.52
30.68
mg/l
—
9
30
9
38
2.49
1.50
1.1
2.9
72.36
227.20
mg/l
—
9
30
10
47
2.25
1.38
2.4
2.7
0.57
0.71
%
—
10
47
10
47
2.25
1.38
2.4
2.7
1.01
1.15
%
—
10
47
94
848
1.96
1.38
36.8
24.6
30.52
30.47
pg
0.13
94
827
94
848
1.96
1.38
37.1
24.9
129.47
132.66
g/l
1.13
94
826
94
848
1.96
1.38
36.9
24.7
92.20
91.92
fl
0.27
94
827
9
42
2.25
1.37
1.1
1.5
33.98
37.32
g/l
—
9
37
76
652
1.59
1.30
9.0
7.1
73.25
81.36
u/l
1.45
71
607
89
794
1.75
1.30
24.3
16.9
34.59
26.37
mg/l
1.14
71
657
39
291
1.54
1.26
4.1
3.3
—
—
—
0
0
38
282
1.54
1.26
5.9
4.3
—
—
—
0
0
10
50
2.10
1.21
1.3
5.8
26.80
24.61
mmol/l
—
10
50
27
188
1.59
1.17
1.4
1.3
—
—
—
0
0
8
41
2.03
1.11
3.1
2.8
4.17
4.36
pmol/l
—
8
36
9
47
2.00
1.05
1.0
1.2
—
—
—
0
0
6
27
2.29
0.95
1.3
1.1
—
—
—
0
0
16
236
0.62
0.95
5.1
3.5
—
—
—
0
0
31
234
1.46
0.92
4.6
3.2
0.65
0.77
ug/l
0.37
22
165
8
43
1.93
0.89
1.6
3.0
—
—
—
0
0
19
130
1.56
0.88
1.6
1.3
2.46
2.64
g/l
—
5
70
6
31
1.99
0.86
3.5
3.3
—
—
—
0
0
15
219
0.63
0.85
1.3
1.8
459.56
465.61
pmol/l
—
9
190
6
32
1.93
0.83
1.2
1.4
—
—
—
0
0
8
47
1.76
0.83
3.4
1.9
8.09
10.42
g/l
—
8
41
17
116
1.55
0.80
1.0
1.3
15.60
38.80
iu/ml
—
5
44
5
23
2.23
0.77
1.0
1.1
—
—
—
0
0
16
224
0.66
0.74
3.7
4.1
—
—
—
0
0
7
43
1.67
0.68
3.0
3.4
9.43
919.32
u/ml
—
7
37
86
798
1.41
0.65
18.0
16.1
—
—
—
0
0
11
73
1.57
0.59
5.7
3.7
—
—
—
0
0
59
526
1.27
0.56
5.3
4.2
6.79
6.92
mmol/l
0.18
59
498
9
62
1.49
0.55
1.2
1.6
—
—
—
0
0
6
40
1.53
0.52
1.0
1.2
—
—
—
0
0
7
47
1.52
0.48
4.0
5.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
3.0
—
—
—
0
0
5
35
1.45
0.40
5.8
4.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
7
56
1.27
0.30
2.3
2.7
0.41
0.13
e6/l
—
7
56
14
115
1.25
0.25
1.5
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
64.73
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
5.03
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
7
58
1.22
0.18
2.1
2.9
—
—
—
0
0
10
82
1.24
0.18
1.1
2.1
—
—
—
0
0
9
77
1.18
0.16
1.1
1.6
471.11
404.31
nmol/l
—
9
70
6
54
1.12
0.09
2.2
1.5
—
—
—
0
0
5
63
0.78
0.08
4.0
2.6
—
7.42
—
0
9
6
73
0.81
0.08
4.5
3.3
—
—
—
0
0
10
95
1.06
0.00
1.2
1.3
—
—
—
0
0
10
101
0.99
0.00
3.1
2.7
12.13
6.34
ug/l
—
10
87
6
67
0.89
0.00
1.7
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
2164.29
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
254.60
—
0
5
0
6
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
319.00
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
31.89
—
0
9
0
6
0.00
-0.00
0.0
3.2
—
8.33
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_SKIN_LIP – Carcinoma in situ of skin of lip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).