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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_SKIN_LIP_EXALLC for full statistics.

Carcinoma in situ of skin of lip

DOID Endpoint Browser

CD2_INSITU_SKIN_LIP

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D04.0&
  • Hospital discharge: ICD-9 — 2320
  • Cause of death: ICD-10 — D04.0&
  • Cause of death: ICD-9 — 2320

2 out of 7 registries used, show all original rules.

97

4. Check minimum number of events

None

97

5. Include endpoints

None

97

6. Filter based on genotype QC (FinnGen only)

97

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D04
Name in latin
Carcinoma in situ cutis labii (oris)

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 97 38 59
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 73.30 73.96 72.88

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
88
Matched controls
880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D04.0
ICD-10 Finland
Carcinoma in situ: Skin of lip
+∞
126.7
88
*
L57.0
ICD-10 Finland
Actinic keratosis
21.7
34.4
59
75
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
18.3
29.6
52
64
TQW99
NOMESCO Finland
Other minor procedure on skin
28.4
29.3
41
26
EAA10
NOMESCO Finland
Excision of lesion of lip
181.4
26.2
26
*
ZXC20
NOMESCO Finland
Use of chemical agents
31.7
20.6
27
12
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
43.6
19.1
23
7
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
22.3
18.5
27
17
L56.8
ICD-10 Finland
Other specified acute skin changes due to ultraviolet radiation
+∞
18.4
17
*
ZQZ00
NOMESCO Finland
Treatment of several skin areas
222.8
18.2
18
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
9.9
17.4
39
65
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
18.8
16.9
26
19
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
22.4
14.7
21
12
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
51.7
14.7
17
*
ZXC10
NOMESCO Finland
Use of laser
44.5
12.7
15
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
9.5
12.2
26
37
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
75.2
11.9
13
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
20.6
11.7
17
10
ZZR00
NOMESCO Finland
Flap of skin
17.0
11.6
18
13
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
7.0
11.6
31
63
EAA30
NOMESCO Finland
Partial excision of lower lip
50.2
11.3
13
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
14.7
10.9
18
15
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.6
10.6
35
92
R4110
NOMESCO Finland
Physiotherapy
4.8
10.4
44
151
D06BB10
ATC
imiquimod; topical
10.7
9.9
19
22
WX002
NOMESCO Finland
Sedation and analgesia
5.1
9.5
34
96
XF400
NOMESCO Finland
ECG with 12 standard connections
4.7
8.9
35
109
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.8
8.6
22
41
D07AB08
ATC
desonide; topical
6.7
8.2
21
39
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
49.5
7.9
9
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.7
7.5
27
75
ZXA05
NOMESCO Finland
Left side
3.6
7.0
41
173

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
88
7.03
19.17
2.6
1.3
—
—
—
0
0
70
271
6.69
17.83
5.2
2.3
—
—
—
0
0
18
21
10.30
14.62
1.3
1.2
—
—
—
0
0
24
64
4.65
8.71
7.0
7.2
—
—
—
0
0
22
64
4.15
7.06
1.2
1.5
—
—
—
0
0
55
290
3.07
6.86
5.1
4.0
51.8
74.9
e6/l
0.29
40
219
45
214
3.06
6.71
4.7
3.2
—
—
—
0
0
47
235
2.94
6.33
4.6
3.2
0.7
0.3
e6/l
0.61
36
180
50
262
2.87
6.13
4.6
3.3
132.6
334.5
e6/l
0.37
40
208
35
152
3.04
6.02
2.2
4.1
—
—
—
0
0
38
184
2.75
5.26
8.7
7.6
—
—
—
0
0
23
85
3.24
5.12
5.4
3.8
5.7
5.7
kpa
0.02
23
80
23
88
3.12
4.82
5.3
3.7
—
—
—
0
0
15
44
3.85
4.68
2.7
2.1
1.8
1.7
g/l
0.17
15
39
22
84
3.09
4.62
1.6
1.3
—
—
—
0
0
80
588
3.06
4.44
35.4
19.3
39.1
38.3
%
0.52
63
359
77
555
2.88
4.44
36.8
22.1
14.2
14.0
%
0.47
77
537
20
76
3.06
4.22
2.3
1.6
—
—
—
0
0
19
72
3.04
4.02
2.7
3.2
4.9
4.2
kpa
0.52
19
67
16
55
3.29
3.95
1.5
1.6
—
—
—
0
0
70
505
2.39
3.63
5.1
4.6
—
—
—
0
0
18
71
2.89
3.54
7.7
5.5
13.0
11.1
mmol/l
0.50
18
66
53
345
2.18
3.49
2.9
2.2
92.4
93.2
pmol/l
0.04
28
174
55
365
2.17
3.43
5.4
3.8
34.4
34.6
g/l
0.08
49
336
26
128
2.41
3.31
2.4
2.7
0.8
0.8
mmol/l
0.83
26
118
8
15
5.70
3.26
2.1
2.5
—
—
—
0
0
7
11
6.76
3.24
2.0
1.8
60.1
65.0
%
—
7
11
53
356
2.08
3.10
8.5
5.4
0.6
0.6
e9/l
0.08
45
306
53
357
2.07
3.07
8.5
5.4
0.0
0.0
e9/l
0.21
44
309
28
147
2.27
3.07
3.9
2.2
11.5
12.6
umol/l
0.38
28
132
41
251
2.10
3.07
7.5
4.8
—
—
—
0
0
5
5
10.44
3.01
1.8
1.2
—
—
—
0
0
69
518
2.15
2.92
5.2
4.2
—
—
—
0
0
18
79
2.57
2.89
1.2
2.4
73.7
67.3
e9/l
—
7
66
8
18
4.74
2.86
1.3
1.1
—
—
—
0
0
53
365
2.00
2.81
8.7
5.7
0.1
0.2
e9/l
1.32
45
320
53
366
1.99
2.78
8.8
5.5
1.9
1.9
e9/l
0.02
45
321
11
38
3.14
2.68
1.6
1.7
—
—
—
0
0
47
315
1.95
2.65
11.4
10.7
0.0
0.0
e9/l
0.38
40
266
11
39
3.05
2.57
1.6
1.5
—
—
—
0
0
11
39
3.05
2.57
2.3
2.5
—
—
—
0
0
18
85
2.37
2.48
3.1
2.5
6.4
12.5
umol/l
1.40
18
75
35
216
1.97
2.47
3.1
2.1
3.1
3.0
mg/l
0.08
30
191
37
233
1.95
2.47
4.5
3.1
109.8
58.8
mg/l
0.28
25
159
12
46
2.84
2.46
7.4
6.4
—
—
—
0
0
22
114
2.20
2.45
6.1
5.5
1.2
1.4
mmol/l
0.05
16
88
21
107
2.23
2.44
1.9
1.7
—
—
—
0
0
38
244
1.92
2.38
3.4
2.3
—
—
—
0
0
56
416
1.82
2.16
12.3
8.6
4.7
4.5
e9/l
0.24
50
364
22
357
0.50
2.11
4.4
4.2
25.1
52.8
ng/l
1.39
17
285
9
32
2.99
2.06
1.1
3.3
72.4
250.8
mg/l
—
9
26
9
32
2.99
2.06
1.1
3.3
52.5
26.0
mg/l
—
9
26
86
742
2.40
2.05
31.3
20.6
100.7
86.2
umol/l
1.18
86
742
10
39
2.74
1.99
1.0
1.4
—
—
—
0
0
32
211
1.77
1.77
3.5
2.7
14656.5
9485.3
umol/l
0.14
26
171
10
42
2.54
1.74
1.3
6.5
26.8
24.5
mmol/l
—
10
42
8
31
2.72
1.70
1.3
1.2
—
—
—
0
0
10
43
2.48
1.66
2.4
2.8
1.0
1.1
%
—
10
43
36
253
1.67
1.57
5.3
3.8
24.4
9.5
mg/mmol
0.41
23
167
85
753
2.04
1.51
31.7
20.2
138.7
139.6
mmol/l
2.06
85
728
85
754
2.03
1.49
32.5
20.2
4.0
4.0
mmol/l
0.51
85
729
9
41
2.31
1.41
1.0
1.3
—
—
—
0
0
36
260
1.61
1.39
4.1
3.4
—
—
—
0
0
36
262
1.59
1.34
6.1
4.4
—
—
—
0
0
6
24
2.60
1.32
1.3
1.1
—
—
—
0
0
81
716
1.80
1.31
25.6
17.1
33.4
27.3
mg/l
0.71
65
593
17
264
0.57
1.29
4.4
4.6
—
—
—
0
0
85
768
1.86
1.19
39.3
25.0
128.4
132.2
g/l
1.37
85
747
85
768
1.86
1.19
39.0
24.8
92.1
91.9
fl
0.13
85
748
85
768
1.86
1.19
38.9
24.7
30.5
30.5
pg
0.00
85
748
5
20
2.58
1.16
1.0
1.1
—
—
—
0
0
25
172
1.61
1.15
1.4
1.2
—
—
—
0
0
8
41
2.03
1.11
3.4
1.7
8.1
10.3
g/l
—
8
35
7
35
2.08
1.02
3.3
2.9
4.0
4.4
pmol/l
—
7
30
7
37
1.96
0.96
1.7
3.1
—
—
—
0
0
6
27
2.30
0.95
1.2
1.5
—
—
—
0
0
17
116
1.56
0.81
1.6
1.3
2.5
2.6
g/l
—
5
62
7
39
1.86
0.74
3.0
3.4
9.4
981.4
u/ml
—
7
34
27
210
1.40
0.69
5.0
3.3
0.6
0.8
ug/l
0.41
19
144
5
29
1.76
0.64
4.0
3.3
—
—
—
0
0
14
194
0.67
0.63
1.4
1.8
459.6
476.6
pmol/l
—
9
168
5
30
1.70
0.62
1.8
2.4
22.8
24.9
mmol/l
—
5
21
15
204
0.69
0.61
5.4
3.5
—
—
—
0
0
78
727
1.37
0.54
19.1
16.1
—
—
—
0
0
54
480
1.28
0.54
5.6
4.3
6.9
7.0
mmol/l
0.10
54
453
9
65
1.42
0.52
1.1
1.6
471.1
409.3
nmol/l
—
9
60
7
45
1.60
0.50
4.0
5.6
—
—
—
0
0
10
70
1.48
0.43
6.2
3.6
—
—
—
0
0
8
59
1.39
0.42
1.3
1.6
—
—
—
0
0
5
33
1.54
0.42
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
0.3
—
0
15
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
1.3
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
16
199
0.77
0.38
3.7
4.3
—
—
—
0
0
9
70
1.31
0.38
1.1
2.3
—
—
—
0
0
13
100
1.35
0.36
1.5
1.4
—
—
—
0
0
7
54
1.32
0.31
2.1
3.0
—
—
—
0
0
11
139
0.76
0.29
7.4
5.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
49.8
—
0
5
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
6
51
1.19
0.20
2.5
2.9
0.0
0.1
e6/l
—
6
51
5
60
0.82
0.08
4.0
2.6
4.9
5.1
kpa
—
5
52
5
62
0.80
0.08
1.8
1.2
—
—
—
0
0
5
63
0.78
0.08
4.4
3.5
—
—
—
0
0
9
84
1.08
0.07
1.1
1.3
—
—
—
0
0
10
93
1.08
0.02
3.1
2.7
12.1
6.1
ug/l
—
10
80
0
9
0.00
0.00
0.0
2.2
—
65.2
—
0
9
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
5.4
—
0
9
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
319.0
—
0
5
0
5
0.00
0.00
0.0
2.4
—
2390.0
—
0
5
5
57
0.87
0.00
4.0
2.6
—
7.4
—
0
8
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
5
50
1.00
0.00
2.4
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
8.8
—
0
5
0
5
0.00
0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
32.0
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_SKIN_LIP – Carcinoma in situ of skin of lip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).