Wilms' tumor

C3_WILMS_TUMOR

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — C64.80& Cause of death: ICD-10 — C64.80& 2 out of 7 registries used, show all original rules.	216
4. Check minimum number of events None	216
5. Include endpoints None	216
6. Filter based on genotype QC (FinnGen only)	216

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF12

NAME	C3_WILMS_TUMOR
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C6480
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C6480
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Wilms' tumor based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Wilms' tumor, excluding all cancers (controls excluding all cancers)

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	216	78	138
Unadjusted period prevalence (%)	0.05	0.03	0.06
Median age at first event (years)	62.86	58.22	65.48

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3003458) Phosphate [Moles/volume] in Serum or Plasma

271

2.81

9.86

12.3

6.4

1.19

1.09

mmol/l

1.59

252

(3023323) Follitropin [Units/volume] in Serum or Plasma

5.13

7.04

3.1

2.1

26.46

18.28

iu/l

—

(3002032) Base excess in Venous blood by calculation

224

2.34

5.61

10.0

5.4

0.21

1.55

mmol/l

1.95

168

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

4.83

5.33

6.0

1.8

29.23

15.86

ug/l

0.86

(3009214) Lutropin [Units/volume] in Serum or Plasma

3.85

5.31

2.8

1.8

16.77

7.53

u/l

—

(3000991) Gas panel - Venous blood

190

2.36

5.14

11.1

7.7

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

226

2.25

5.08

10.3

5.4

5.51

5.67

kpa

0.61

218

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

127

2.48

4.43

1.4

1.6

—

(3021901) Oxygen saturation in Capillary blood

3.51

4.41

4.6

3.7

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

12.00

4.30

8.6

4.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

3.36

4.14

1.3

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

642

1.79

4.13

5.8

3.8

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

101

718

1.76

4.04

8.5

5.2

34.18

34.91

g/l

0.78

671

(3030981) Hyaline casts [#/volume] in Urine by Automated count

109

2.46

3.86

3.8

3.4

0.12

0.27

e6/l

1.13

109

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

402

1.84

3.84

3.8

2.5

—

(40761511) CBC panel - Blood by Automated count

134

1603

0.57

3.78

31.6

15.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

108

1358

0.59

3.56

29.4

16.0

62.90

75.62

ml/min/173m2

4.07

1098

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

116

1428

0.59

3.45

3.9

4.8

5.82

6.07

mmol/l

1.27

109

1280

(3018095) Leukocytes [#/volume] in Urine

642

1.66

3.19

6.0

4.5

29.05

83.84

e6/l

2.11

479

(3030467) Casts [#/volume] in Urine by Automated count

509

1.69

3.17

5.3

3.8

0.14

0.48

e6/l

1.72

394

(3017143) Hepatitis C virus Ab [Presence] in Serum

156

2.07

3.08

2.1

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

731

1.62

3.04

6.1

4.2

—

(3052851) Hemolysis interference index of Serum or Plasma

2.75

3.03

6.5

3.7

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

4.42

3.03

7.4

6.5

10.73

12.10

mg/l

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

3.26

2.97

1.4

1.7

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

2.55

2.96

2.2

1.7

3.05

5.47

ug/l

0.23

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

110

850

1.60

2.91

17.0

6.9

1.23

1.21

mmol/l

1.32

105

718

(3024354) Oxygen [Partial pressure] in Venous blood

198

1.92

2.86

10.0

5.2

5.54

4.57

kpa

1.10

190

(3044640) Blood type and Crossmatch panel - Blood

530

1.64

2.85

4.1

2.5

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

2.66

2.85

2.9

2.5

0.30

0.33

u/ml

—

(44806118)

4.04

2.80

1.3

1.6

—

(44790049)

4.04

2.80

1.3

1.6

—

(44790047)

4.04

2.80

1.3

1.6

—

(44790048)

4.04

2.80

1.3

1.6

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

258

1.78

2.65

6.1

2.7

22.47

21.94

0.10

227

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

205

1.84

2.57

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

208

1.81

2.46

1.8

1.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

297

1.70

2.44

2.2

1.9

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

178

1.87

2.42

6.5

5.5

1.98

1.86

mmol/l

0.07

129

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

3.73

2.39

1.5

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.64

2.31

1.3

1.7

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

297

1.65

2.19

2.4

2.3

29.27

29.66

0.20

288

(36304419) Bacteria [Presence] in Urine

478

1.55

2.19

5.4

3.7

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

4.38

2.16

6.7

3.9

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

143

1617

0.66

2.14

20.6

10.7

33.96

24.71

u/l

0.54

137

1548

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

110

2.01

2.14

4.8

3.5

53.40

59.98

ml/min/173m2

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

115

1355

0.68

2.11

4.4

4.1

1.40

1.24

mmol/l

1.53

110

1224

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.26

2.10

1.1

1.3

—

(3018418) pH of Serum or Plasma

483

1.53

2.08

11.9

3.8

7.38

7.40

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

121

1408

0.68

2.04

4.4

4.6

4.45

4.38

mmol/l

0.29

116

1290

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

321

1.59

2.00

5.4

4.0

168.02

210.02

ng/l

0.16

265

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

3.82

1.95

2.0

1.6

—

nmol/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

207

1.70

1.94

2.1

1.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

119

1383

0.69

1.93

7.4

4.4

2.04

2.06

mu/l

0.06

114

1221

(3013650) Neutrophils [#/volume] in Blood by Automated count

113

932

1.45

1.93

19.0

9.3

3.97

4.27

e9/l

0.71

106

804

(3026008) Bacteria identified in Urine by Culture

527

1.49

1.91

3.6

3.4

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

118

1371

0.69

1.89

6.3

6.5

41.98

40.96

mmol/mol

0.33

113

1266

(3023520) Reticulocytes [#/volume] in Blood

177

1.74

1.88

2.6

2.7

59.19

67.19

e9/l

0.87

141

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.08

1.85

6.0

7.8

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

2.82

1.81

1.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

3.40

1.76

2.2

1.6

—

(40761536) Microorganisms panel - Urine sediment

130

0.37

1.69

18.4

4.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.31

1.66

1.4

1.3

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

145

1610

0.70

1.65

39.7

19.8

4.18

4.01

mmol/l

8.31

139

1562

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

2.75

1.59

4.0

12.3

—

722.57

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

3.06

1.59

1.2

1.6

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

3.06

1.59

1.2

1.6

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

3.06

1.59

1.2

1.6

—

(1761868) Lipid panel - Serum or Plasma

442

0.63

1.58

2.7

3.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

145

1606

0.70

1.58

39.2

19.8

139.06

139.54

mmol/l

1.37

139

1557

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

407

0.62

1.56

2.7

3.2

0.72

0.83

ug/l

0.38

287

(40768441) Liver Pathology biopsy report

3.39

1.53

1.2

1.3

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

2.64

1.53

1.1

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

142

1574

0.71

1.50

33.2

16.7

29.02

26.20

mg/l

0.47

128

1274

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

183

1.61

1.43

1.6

4.4

3.26

31.77

ug/l

0.68

154

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.23

1.42

1.6

1.5

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.23

1.42

1.6

1.5

—

(3044889) 12 lead EKG panel

1025

0.73

1.42

4.3

4.2

—

(3023368) Bacteria identified in Blood by Culture

527

1.39

1.40

6.5

4.4

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

2.54

1.31

1.0

1.5

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

163

1.60

1.30

3.1

2.3

362.68

381.30

nmol/l

0.21

148

(3020630) Protein [Mass/volume] in Serum or Plasma

147

1.63

1.29

4.7

2.0

65.07

66.28

g/l

0.28

133

(3035637) Corticotropin [Mass/volume] in Plasma

2.33

1.28

1.4

1.6

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.91

1.27

5.1

3.0

4.19

4.57

pmol/l

0.56

(3007853) Bacteria identified in Skin by Aerobe culture

215

1.52

1.25

2.0

1.8

—

(3022313) Gas panel - Capillary blood

149

1.61

1.23

6.3

5.4

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

2.67

1.22

1.0

—

(3003396) Base excess in Arterial blood by calculation

208

1.51

1.21

4.4

5.9

-0.28

0.91

mmol/l

0.58

169

(3008757) Leukocyte morphology finding [Identifier] in Blood

2.34

1.19

1.5

5.3

—

(40758558) Short blood count panel - Blood

425

1.36

1.12

18.0

7.6

—

(3022217) INR in Platelet poor plasma by Coagulation assay

256

1.44

1.10

21.4

28.6

1.54

1.32

inr

0.41

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.23

1.09

1.0

1.4

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

205

1.48

1.08

4.5

5.9

4.70

4.99

kpa

1.11

199

(3027801) Oxygen [Partial pressure] in Arterial blood

205

1.48

1.08

4.5

5.9

12.39

11.99

kpa

0.09

199

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

688

0.75

1.06

6.3

4.3

62.19

47.09

ng/l

0.53

517

(40760892) CBC W Ordered Manual Differential panel - Blood

312

1.39

1.04

5.7

4.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

2.09

1.04

2.4

—

(3042936) Bacteria identified in Isolate by Culture

251

1.42

1.02

2.1

2.0

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.03

1.01

1.1

1.3

—

(3021589) Normoblasts [#/volume] in Blood

746

0.76

1.00

22.6

10.5

0.00

e9/l

0.53

602

(40768797) Stomach Pathology biopsy report

209

0.60

0.99

1.2

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

142

0.55

0.97

1.5

1.7

—

(3000492) Spirometry study

117

0.50

0.97

1.0

1.5

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.97

0.0

1.4

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

574

0.75

0.96

4.5

4.7

20.72

21.41

0.14

298

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.96

0.0

1.5

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

2.17

0.92

1.3

—

(3051611) Lipemic interference index of Serum or Plasma

2.17

0.92

9.8

3.4

—

(4035726)

144

1.51

0.91

1.4

—

(3037756) Immunofixation for Serum or Plasma

1.94

0.89

1.0

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.82

0.89

1.0

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

427

0.73

0.88

9.9

4.3

0.00

estimate

—

131

(3019150) Specific gravity of Urine by Refractometry

349

1.33

0.87

6.7

4.6

1.01

1.02

kg/l

2.27

(4010399)

112

0.52

0.86

1.0

1.4

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

1.81

0.85

1.8

1.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.79

0.85

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.79

0.85

1.0

1.2

—

(1616796) Gas panel - Central venous blood

1.90

0.82

14.0

4.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.57

0.81

1.4

1.3

—

(3032080) INR in Blood by Coagulation assay

702

1.25

0.80

12.0

10.1

1.35

inr

0.01

187

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.78

0.0

1.0

—

44.83

—

(3019225) pH of Specimen

150

1.44

0.77

8.9

4.1

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.73

0.76

2.1

2.2

82.68

197.96

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.73

0.76

2.1

2.2

70.23

33.90

mg/l

—

(3019060) Gas panel - Arterial blood

125

1.48

0.75

1.9

3.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

311

1.31

0.75

4.1

3.3

1.05

0.98

e6/l

0.05

193

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

2.11

0.75

1.0

1.2

—

(3019230) Fractional oxyhemoglobin in Venous blood

2.11

0.75

13.4

8.1

65.60

65.23

—

(3009542) Hematocrit [Volume Fraction] of Blood

128

1384

0.82

0.74

35.0

18.2

35.55

38.66

2.04

960

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.02

0.73

5.0

3.2

53.00

60.12

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.02

0.73

4.4

2.9

3.94

4.41

e9/l

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

113

1023

1.22

0.73

6.9

5.0

6.90

6.72

mmol/l

0.33

108

962

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

145

0.60

0.72

1.3

1.7

—

(3051651) Icteric interference index of Serum or Plasma

1.94

0.71

11.2

3.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

686

0.81

0.69

1.9

2.1

95.89

91.35

pmol/l

0.37

352

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

356

0.75

0.67

1.3

0.71

1.65

u/ml

—

(3037467) Urinalysis macro (dipstick) panel - Urine

121

1112

1.20

0.64

7.3

4.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

254

0.72

0.63

1.7

1.8

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.60

0.0

1.3

—

5.14

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.60

0.0

1.3

—

3.94

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.60

0.0

1.2

—

0.16

—

(3008898) HLA-B27 [Presence]

1.69

0.57

1.0

1.1

—

(3019198) Lymphocytes [#/volume] in Blood

842

1.18

0.56

11.1

6.3

1.84

1.93

e9/l

0.39

740

(36660697) Celiac disease serology panel - Serum

124

0.63

0.56

1.3

1.2

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

193

0.71

0.56

1.5

1.3

34.33

11.40

u/ml

—

(3006315) Basophils [#/volume] in Blood

823

1.18

0.56

10.7

6.3

0.04

e9/l

1.00

704

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.49

0.55

1.1

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.55

0.53

1.7

1.2

—

(3023183) Ammonium ion [Moles/volume] in Plasma

1.51

0.52

2.3

2.6

28.00

35.42

umol/l

—

(3013512) EKG study

471

1.20

0.49

5.1

4.7

—

(3001604) Monocytes [#/volume] in Blood

821

1.16

0.49

10.8

6.3

0.64

0.62

e9/l

0.26

698

(3013115) Eosinophils [#/volume] in Blood

851

1.16

0.48

12.9

6.5

0.27

0.20

e9/l

1.00

739

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

909

0.86

0.48

3.6

3.0

—

(40761535) Cells panel - Urine sediment

129

1.34

0.47

5.7

3.7

—

(21494755) Public health laboratory ask at order entry panel

0.59

0.46

1.2

1.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.58

0.46

2.8

2.5

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

1.58

0.42

16.6

4.2

—

(42870588) Differential panel, method unspecified - Blood

594

1.16

0.42

10.5

6.4

—

(3024928) Oxygen saturation in Venous blood

1.53

0.41

13.4

6.6

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.41

0.0

1.2

—

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

2.6

—

60.53

—

(4146454)

0.00

0.41

0.0

3.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.35

0.40

1.0

2.0

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.48

0.40

1.2

1.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.40

0.0

1.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.39

0.0

1.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

1.36

0.37

2.8

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

1.31

0.33

1.5

2.4

332.50

77.32

ug/min

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.28

0.32

1.0

1.1

—

(3022145) Colonoscopy Study observation

153

0.77

0.32

1.4

1.3

—

(3009508) Creatinine [Moles/volume] in Urine

510

1.13

0.30

4.1

3.4

5.92

7.32

mmol/l

2.25

418

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

308

1.16

0.30

4.3

3.5

0.97

1.69

e6/l

0.64

193

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

130

1.25

0.29

7.9

6.0

24.70

24.77

mmol/l

0.04

124

(1761482) Bacteria [#/volume] in Urine by Culture

1.30

0.28

4.9

5.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.69

0.26

1.6

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.24

0.26

2.9

1.8

—

(3000494) Fungus identified in Specimen by Culture

191

0.82

0.25

1.6

1.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.23

0.25

1.4

2.2

—

(3020891) Body temperature

1.23

0.25

8.8

3.8

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.30

0.24

2.9

2.0

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

136

0.80

0.24

20.0

4.3

1.23

1.22

mmol/l

0.42

119

(3025941) Bacteria identified in Stool by Culture

1.26

0.23

1.0

1.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.29

0.23

1.0

1.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.22

0.22

2.8

1.5

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.22

0.22

1.2

1.3

—

(3016879) Cocaine [Presence] in Urine

1.19

0.21

1.0

1.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

570

1.10

0.21

3.7

3.6

3249.67

1748.98

ng/l

1.30

485

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.1

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.0

—

17.92

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

0.21

0.0

2.1

—

87.63

—

(3028433) Virus identified in Specimen by Culture

0.00

0.21

0.0

1.4

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.21

0.0

1.6

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.21

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.1

—

(3017569) Oxygen content in Arterial blood

0.00

0.21

0.0

1.7

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.1

—

1.80

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.17

0.21

2.8

1.5

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.26

0.21

1.0

1.3

3.26

3.77

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.26

0.21

1.0

1.3

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.26

0.21

1.0

1.3

7.94

7.54

g/l

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

27.46

—

(3000330) Specific gravity of Urine by Test strip

1.22

0.20

4.8

4.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

780

0.92

0.19

9.8

5.9

0.00

estimate

—

138

(3041096) Erythrocytes [Presence] in Urine by Automated

434

0.90

0.19

6.3

3.9

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

368

1.11

0.19

6.6

4.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.17

0.18

2.9

2.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

341

1.10

0.17

2.1

2.0

1.08

1.60

mg/l

1.33

267

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

120

0.83

0.17

1.6

2.1

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.72

0.17

1.0

1.3

2.20

0.20

g/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

130

0.84

0.16

1.8

2.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

213

0.88

0.15

1.3

1.2

20.93

42.93

iu/ml

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

169

0.88

0.13

3.1

3.8

—

(3035350) Ketones [Presence] in Urine by Test strip

775

0.95

0.10

7.1

4.2

0.00

estimate

—

140

(3027008) Opiates [Presence] in Urine

1.11

0.10

1.0

1.2

—

(3000764) Benzodiazepines [Presence] in Urine

1.11

0.10

1.0

1.3

—

(3028300) Cannabinoids [Presence] in Urine

1.11

0.10

1.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

1.11

0.10

1.0

1.3

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

1.09

0.09

8.0

2.3

123.60

128.91

g/l

—

(3017181) Myelocytes/100 leukocytes in Blood

126

1.12

0.09

2.4

3.9

0.29

0.87

—

(3045414) Leukocytes [Presence] in Urine

1.09

0.09

2.5

1.8

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.09

0.09

1.3

1.5

—

(3002179) Metamyelocytes/100 leukocytes in Blood

107

1.13

0.08

2.5

4.0

0.60

0.45

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.80

0.08

2.2

1.8

—

(3013707) Erythrocyte sedimentation rate by Westergren method

118

1158

1.04

0.08

6.1

4.2

15.49

14.21

mm/h

0.32

112

1056

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.14

0.08

1.1

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

176

1.09

0.08

17.7

8.7

—

(3049717) Cytology report of Urine Cyto stain

1.07

0.07

2.3

2.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

326

0.94

0.07

1.3

1.5

2.44

2.59

g/l

0.16

180

(3009261) Glucose [Presence] in Urine by Test strip

789

0.96

0.07

7.1

4.2

0.00

estimate

—

131

(3020682) Albumin/Creatinine [Ratio] in Urine

494

1.04

0.06

4.8

3.9

29.38

9.12

mg/mmol

1.63

325

(3003694) ABO and Rh group [Type] in Blood

415

0.96

0.06

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.12

0.05

1.2

1.1

—

(40768804) Tissue Pathology biopsy report

605

0.97

0.05

2.3

2.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

262

0.95

0.05

2.6

1.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

140

1.08

0.04

2.1

1.8

—

(3012516) Albumin [Mass/volume] in Urine

467

1.04

0.04

4.0

3.1

1260.63

202.03

mg/l

0.49

319

(3025159) Blasts/100 leukocytes in Blood

109

0.91

0.04

2.8

4.1

0.00

0.23

—

(3002256) Pathology report gross observation

190

1.06

0.04

1.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

126

0.95

0.00

2.3

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

136

1.03

0.00

1.3

1.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

105

1.05

0.00

1.3

1.8

—

(3022621) pH of Urine by Test strip

115

1.05

0.00

3.6

2.9

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

0.0

2.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.1

—

139.88

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

3.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(3008536) Aspergillus sp Ab [Presence] in Serum

0.00

0.0

1.7

—

(4027681)

0.00

0.0

1.3

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(44806420)

0.00

0.0

2.6

—

(44813793)

0.00

0.0

1.1

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

2.6

—

6.79

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1715.80

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

0.0

1.3

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

0.97

0.00

1.2

1.7

36.78

38.07

u/l

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

0.0

3.6

—

14.37

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

1.66

—

(3022670) pH of Venous cord blood

0.00

0.0

1.0

—

(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.2

—

85.40

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3018851) Theophylline [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

34.60

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

57.67

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

105.33

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.3

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.1

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.8

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.4

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

1253.00

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.2

—

(3032352) Blasts [#/volume] in Cerebral spinal fluid

0.00

0.0

8.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

600

1.00

0.00

7.6

4.5

—

(3011544) Albumin [Mass/volume] in Pleural fluid

0.00

0.0

1.0

—

18.47

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.0

14.2

—

9.94

—

(3045716) Anion gap in Serum or Plasma

0.00

0.0

3.0

—

8.54

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3013336) Amino acids [Identifier] in Serum or Plasma

0.00

0.0

1.2

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

110

1.00

0.00

2.1

1.5

—

(3000012) Reticulocyte production index

0.00

0.0

1.7

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

5.5

—

0.59

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3005322) IgE [Units/volume] in Serum or Plasma

0.88

0.00

1.1

1.3

104.90

441.03

u/ml

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.1

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.3

—

(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma

0.00

0.0

3.4

—

(40765096) Chromosome analysis panel by Banding

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

0.0

1.0

—

176.83

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.3

—

37.52

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.8

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_WILMS_TUMOR – Wilms' tumor

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Wilms' tumor

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Wilms' tumor (C3_WILMS_TUMOR)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints