Retained (old) intraocular foreign body

H7_INTRAOCULARBODY

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H44.6, H44.7 Hospital discharge: ICD-9 — 360[5-6] Cause of death: ICD-10 — H44.6, H44.7 Cause of death: ICD-9 — 360[5-6] 2 out of 7 registries used, show all original rules.	33
4. Check minimum number of events None	33
5. Include endpoints None	33
6. Filter based on genotype QC (FinnGen only)	33

Control definitions (FinnGen only)

Control exclude: H7_VITREOUS

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	H7_INTRAOCULARBODY
CONTROL_EXCLUDE	H7_VITREOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H44[6-7]
HD_ICD_9	360[5-6]
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H44[6-7]
COD_ICD_9	360[5-6]
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Retained (old) intraocular foreign body based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	469	90	374
Only index persons	437	77	360
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	46.68	74.62	39.71
Only index persons	45.40	74.26	39.23

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	33	-	29
Unadjusted period prevalence (%)	0.01	-	0.01
Median age at first event (years)	46.38	-	45.75

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3013512) EKG study

3.40

2.84

2.1

3.7

—

(3000330) Specific gravity of Urine by Test strip

8.14

2.64

3.6

3.4

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

3.49

1.49

2.2

2.6

0.1

e6/l

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

1.03

0.0

1.9

—

40.5

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

2.07

0.95

1.6

1.7

2.5

2.9

mg/l

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.82

0.0

10.3

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

158

0.54

0.80

5.0

3.0

15.6

15.1

pmol/l

0.38

146

(3021589) Normoblasts [#/volume] in Blood

108

1.71

0.70

9.3

9.7

0.0

e9/l

0.49

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.93

0.63

1.3

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.62

0.0

1.8

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

1.67

0.60

2.3

5.1

30.6

50.1

ng/l

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

1.56

0.58

3.6

861.7

846.2

ng/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

208

0.62

0.57

5.1

3.6

1.7

1.9

mu/l

0.42

186

(3022145) Colonoscopy Study observation

1.78

0.46

1.0

1.5

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.55

0.42

50.0

21.3

—

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.42

0.0

1.6

—

(3019060) Gas panel - Arterial blood

0.00

0.42

0.0

4.1

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

0.64

0.38

3.7

4.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.41

0.32

3.9

2.6

—

(1002224) Polysomnography panel

0.00

0.22

0.0

1.1

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.22

0.0

1.0

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

0.00

0.22

0.0

2.1

—

0.4

—

(4034850)

0.00

0.22

0.0

18.3

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.22

0.0

1.3

—

1.2

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.22

0.0

2.6

—

(3016879) Cocaine [Presence] in Urine

0.00

0.22

0.0

1.1

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.22

0.0

1.2

—

(3020891) Body temperature

0.00

0.22

0.0

5.3

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.22

0.0

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

2.3

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.22

0.0

1.3

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.22

0.0

1.2

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.22

0.0

1.1

—

(3027008) Opiates [Presence] in Urine

0.00

0.22

0.0

1.2

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.22

0.0

1.1

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

3.2

—

1.6

—

(3026008) Bacteria identified in Urine by Culture

1.24

0.21

3.2

2.7

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.21

0.0

1.8

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.21

0.0

1.3

—

(3026782) Osmolality of Urine

1.21

0.21

3.0

2.7

549.2

575.9

mosm/kgh2o

—

(3013707) Erythrocyte sedimentation rate by Westergren method

160

1.27

0.20

4.9

5.1

10.8

10.4

mm/h

0.04

153

(3013650) Neutrophils [#/volume] in Blood by Automated count

139

0.79

0.19

12.6

12.0

4.2

4.6

e9/l

0.28

122

(3020564) Creatinine [Moles/volume] in Serum or Plasma

259

0.86

0.18

19.5

17.2

83.4

84.0

umol/l

0.05

259

(3026493) Urate [Moles/volume] in Serum or Plasma

0.76

0.18

1.8

2.8

353.7

365.3

umol/l

—

(42870588) Differential panel, method unspecified - Blood

1.25

0.18

7.6

6.1

—

(3032080) INR in Blood by Coagulation assay

1.27

0.17

7.3

4.5

1.6

1.2

inr

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

1.17

0.17

1.8

3.2

48.7

56.4

u/l

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

1.23

0.13

2.4

3.5

27.1

33.1

u/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

1.20

0.10

3.5

6.8

1.2

mmol/l

0.49

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

137

1.17

0.10

4.1

6.6

8.4

12.6

umol/l

2.25

130

(3000850) Epithelial cells [#/volume] in Urine

0.77

0.09

2.0

2.6

3.0

4.2

e6/l

—

(3007461) Platelets [#/volume] in Blood

266

0.89

0.09

21.3

247.0

236.5

e9/l

0.45

259

(3035941) MCH [Entitic mass]

266

0.89

0.09

21.3

21.2

31.0

30.6

0.68

261

(3010813) Leukocytes [#/volume] in Blood

266

0.89

0.09

21.5

21.3

6.8

6.7

e9/l

0.06

259

(3024731) MCV [Entitic volume]

266

0.89

0.09

21.3

21.2

92.1

91.4

0.49

261

(3026361) Erythrocytes [#/volume] in Blood

266

0.89

0.09

21.3

4.6

e12/l

0.04

259

(3000963) Hemoglobin [Mass/volume] in Blood

266

0.89

0.09

21.6

21.4

141.6

g/l

0.00

261

(40758558) Short blood count panel - Blood

1.10

0.09

6.7

7.9

—

(3019198) Lymphocytes [#/volume] in Blood

118

1.17

0.08

9.8

7.6

1.9

1.7

e9/l

0.41

107

(36304419) Bacteria [Presence] in Urine

1.15

0.08

4.0

2.6

—

(3015736) pH of Urine

1.12

0.08

3.1

3.4

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.12

0.08

2.3

2.1

101.8

134.0

ug/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

119

1.15

0.07

3.8

4.5

20.4

21.9

—

(1761868) Lipid panel - Serum or Plasma

110

0.87

0.06

3.0

2.7

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

150

1.13

0.06

5.6

4.5

22.2

2.0

ug/l

0.53

132

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

141

1.12

0.04

4.0

2.9

—

(3006315) Basophils [#/volume] in Blood

113

1.10

0.02

8.2

7.6

0.0

e9/l

1.14

102

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.09

0.01

3.8

3.0

—

(3001604) Monocytes [#/volume] in Blood

114

1.08

0.01

8.2

7.5

0.7

0.6

e9/l

0.57

102

(3037467) Urinalysis macro (dipstick) panel - Urine

155

0.94

0.00

4.1

3.6

—

(3044889) 12 lead EKG panel

165

0.94

0.00

5.2

3.9

—

(3013115) Eosinophils [#/volume] in Blood

115

1.07

0.00

8.7

7.8

0.2

e9/l

0.12

106

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

187

1.04

0.00

2.0

3.1

45.6

61.3

u/l

0.81

175

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

192

0.98

0.00

6.8

8.3

72.9

76.2

u/l

0.26

183

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

0.2

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

239

1.02

0.00

16.4

16.7

139.8

139.5

mmol/l

0.32

230

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.9

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.3

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.0

5.5

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

0.0

1.8

—

3.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

0.0

5.5

—

42.7

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3022313) Gas panel - Capillary blood

0.00

0.0

1.7

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.0

2.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.0

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.0

1.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

2.0

—

(4094501)

0.00

0.0

1.0

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.0

1.3

—

90.7

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

7.7

—

183.7

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.0

1.5

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3003181) Sodium [Moles/volume] in Urine

0.00

0.0

1.7

—

67.5

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.0

1.3

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.00

0.0

1.9

—

23.7

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.0

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.2

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.0

1.7

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

0.0

5.5

—

28.9

—

(3023183) Ammonium ion [Moles/volume] in Plasma

0.00

0.0

1.7

—

36.5

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.0

2.0

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.7

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

0.00

0.0

1.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

6.3

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

1.9

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.0

1.0

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.0

2.3

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.0

1.9

—

6.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

239

1.02

0.00

4.2

4.5

4.6

mmol/l

0.24

219

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.2

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.2

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(40761511) CBC panel - Blood by Automated count

251

0.98

0.00

10.2

12.2

—

(1616796) Gas panel - Central venous blood

0.00

0.0

1.3

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.6

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

2.4

—

3.7

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.7

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.2

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.0

2.6

—

4.9

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

3.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.6

—

(3023368) Bacteria identified in Blood by Culture

0.86

0.00

4.2

4.9

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

0.00

0.0

2.9

—

522.1

—

(40768804) Tissue Pathology biopsy report

1.02

0.00

2.8

1.8

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

243

0.95

0.00

16.6

3.9

4.0

mmol/l

0.69

234

(40760892) CBC W Ordered Manual Differential panel - Blood

0.95

0.00

7.4

7.8

—

(44790048)

0.00

0.0

1.8

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

247

1.05

0.00

4.2

5.0

2.7

2.8

mmol/l

0.13

225

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.0

2.6

—

9.5

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

230

1.00

0.00

5.7

5.6

42.5

41.5

mmol/mol

0.15

210

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

7.2

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

1.6

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

1.02

0.00

3.0

1.6

2.5

1.4

mmol/l

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.02

0.00

3.9

3.7

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.0

1.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3009508) Creatinine [Moles/volume] in Urine

0.87

0.00

4.2

3.5

9.9

8.7

mmol/l

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.0

1.3

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

237

1.05

0.00

4.2

4.5

1.2

1.4

mmol/l

1.86

216

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

2.6

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(44790049)

0.00

0.0

1.8

—

(3036489) Thrombin time

0.00

0.0

1.4

—

21.2

—

(44806118)

0.00

0.0

1.8

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

1.8

—

(44790047)

0.00

0.0

1.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(3044640) Blood type and Crossmatch panel - Blood

1.02

0.00

1.7

2.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_INTRAOCULARBODY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_INTRAOCULARBODY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_INTRAOCULARBODY – Retained (old) intraocular foreign body

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Retained (old) intraocular foreign body

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints