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This is a non-core endpoint: only basic statistics are computed.

Abnormal findings in bronchial washings nasal secretions pleural fluid sputum throat scrapings

R18_ABNORMAL_FINDI_BRONCHIAL_WASHI_NASAL_SECRE_PLEURAL_FLUID_SPUTUM_THROAT_SCRAP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R84
  • Cause of death: ICD-10 R84

2 out of 7 registries used, show all original rules.

103

4. Check minimum number of events

None

103

5. Include endpoints

None

103

6. Filter based on genotype QC (FinnGen only)

103

Control definitions (FinnGen only)

Control exclude
R18_ABNORMAL_FINDI_EXAMI_OTHER_BODY_FLUIDS_SUBST_TISSU_WO_DIAGNOSIS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
R8[3-9]
Name in latin
Reperta abnormia in speciminibus ex organis respiratoriis et thorace

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 103 46 57
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 64.20 58.77 68.58

-FinnGen-

Age distribution of first events

0304050607080900246810121416182022242628AgeIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520002005201020152020202302468101214161820222426YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
97
Matched controls
969
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R84.6
ICD-10 Finland
Abnormal findings in specimens from respiratory organs and thorax, abnormal cytological findings
+∞
35.6
32
*
R84.9
ICD-10 Finland
Abnormal findings in specimens from respiratory organs and thorax, unspecified abnormal finding
+∞
22.8
21
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
12.6
19.8
38
47
R84.0
ICD-10 Finland
Abnormal findings in specimens from respiratory organs and thorax, abnormal level of enzymes
+∞
17.2
16
*
R84.5
ICD-10 Finland
Abnormal findings in specimens from respiratory organs and thorax, abnormal microbiological findings
+∞
13.9
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.1
13.6
33
58
R84.8
ICD-10 Finland
Abnormal findings in specimens from respiratory organs and thorax, other abnormal findings
+∞
9.5
9
*
H02AB06
ATC
prednisolone; systemic
3.1
6.8
62
349
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
6.5
43
195

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
62
4.24
7.34
5.8
3.4
—
—
—
0
0
15
36
4.71
6.05
5.0
3.4
1.82
1.21
%
0.87
15
36
45
231
2.68
5.53
6.0
4.2
—
—
—
0
0
10
18
6.05
5.44
1.2
1.8
0.28
0.23
g/l
—
10
18
10
19
5.72
5.15
1.2
1.8
1.26
1.11
g/l
—
10
19
22
79
3.27
5.10
2.9
1.6
—
—
—
0
0
34
158
2.72
5.01
2.1
1.6
3.21
1.03
mg/l
0.51
29
124
8
7
12.25
4.87
2.5
1.3
—
—
—
0
0
8
7
12.25
4.87
2.3
1.3
1.95
2.09
g/l
—
8
7
13
34
4.23
4.70
7.2
5.1
—
—
—
0
0
20
74
3.11
4.39
5.8
3.4
—
—
—
0
0
17
57
3.37
4.36
1.2
2.3
64.68
66.52
g/l
0.32
17
48
20
75
3.07
4.29
4.6
3.9
—
—
—
0
0
62
404
2.34
4.23
10.8
5.5
0.18
0.19
e9/l
0.23
57
353
7
7
10.61
4.07
2.4
1.3
5.83
6.01
g/l
—
7
7
61
400
2.29
4.04
10.5
5.1
1.75
1.99
e9/l
0.74
55
352
60
392
2.27
3.99
10.6
5.1
0.04
0.04
e9/l
0.03
55
336
60
392
2.27
3.99
10.5
5.0
0.57
0.60
e9/l
0.39
55
336
8
11
7.77
3.94
2.3
1.3
0.39
0.51
g/l
—
8
11
26
118
2.61
3.93
4.0
1.8
—
—
—
0
0
18
67
3.04
3.90
13.2
7.3
—
—
—
0
0
11
30
3.99
3.75
19.0
16.7
—
—
—
0
0
25
114
2.58
3.73
9.0
5.1
1.05
1.01
mmol/l
0.28
25
100
33
174
2.32
3.60
6.2
3.5
—
—
—
0
0
8
13
6.57
3.57
5.8
2.5
—
—
—
0
0
37
206
2.24
3.54
6.5
4.2
0.00
0.00
estimate
—
10
70
53
341
2.14
3.53
7.8
4.4
32.68
54.80
ng/l
0.88
43
258
21
90
2.67
3.53
2.6
1.6
—
—
—
0
0
58
395
2.07
3.24
13.7
5.7
1.20
1.21
mmol/l
0.78
49
331
30
160
2.23
3.14
9.4
5.2
—
—
—
0
0
44
273
2.07
3.14
8.4
4.6
—
—
—
0
0
17
70
2.71
3.07
9.4
7.5
12.18
9.51
mmol/l
0.89
17
65
11
35
3.40
3.03
5.8
3.5
0.76
0.72
%
0.12
11
35
22
104
2.42
3.02
1.3
1.3
—
—
—
0
0
8
17
5.01
2.98
5.4
1.2
—
—
—
0
0
13
47
3.02
2.94
10.0
2.9
—
—
—
0
0
11
37
3.21
2.78
18.4
7.1
—
—
—
0
0
25
130
2.22
2.76
1.2
1.2
14.19
21.67
iu/ml
—
7
42
6
10
6.29
2.73
1.0
1.0
—
—
—
0
0
5
7
7.43
2.57
1.0
1.6
14.22
13.34
ug/l
—
5
7
13
52
2.72
2.47
12.6
4.6
26.05
25.18
mmol/l
0.30
13
52
13
52
2.72
2.47
1.3
1.6
—
—
—
0
0
54
383
1.86
2.46
5.8
3.7
0.00
0.00
estimate
—
10
72
15
65
2.53
2.45
10.1
2.8
—
7.44
—
0
5
63
470
1.88
2.44
12.7
8.8
4.24
4.25
e9/l
0.01
58
406
6
12
5.23
2.44
1.2
1.3
—
—
—
0
0
5
8
6.50
2.40
2.4
4.1
—
—
—
0
0
13
53
2.66
2.38
3.9
5.4
2.83
0.31
%
—
6
13
54
389
1.82
2.29
5.9
3.7
0.00
0.00
estimate
—
10
67
24
132
2.07
2.28
5.8
2.7
0.80
0.82
mmol/l
0.36
24
119
36
229
1.88
2.27
3.7
3.1
32.41
56.91
mg/l
0.66
23
158
33
205
1.90
2.23
1.9
1.6
21.27
20.17
nmol/l
0.14
26
168
53
383
1.79
2.20
7.4
4.9
0.00
0.00
estimate
—
10
70
6
14
4.48
2.18
1.2
1.1
—
—
—
0
0
6
14
4.48
2.18
3.2
2.3
—
—
—
0
0
43
295
1.79
2.11
5.7
3.6
—
—
—
0
0
20
106
2.10
2.09
1.5
1.6
—
—
—
0
0
24
139
1.95
1.98
1.9
1.5
2.90
3.20
g/l
0.12
18
68
26
155
1.91
1.97
1.3
1.4
0.55
1.10
u/ml
—
6
42
6
16
3.91
1.96
1.2
1.3
—
—
—
0
0
10
40
2.66
1.90
1.3
1.3
—
—
—
0
0
76
629
1.79
1.82
14.6
6.5
87.49
79.45
u/l
0.67
76
586
36
244
1.73
1.79
4.6
3.7
4.36
7.56
mg/mmol
0.77
27
161
13
62
2.26
1.74
5.1
5.0
3.29
0.84
%
—
7
25
45
331
1.64
1.63
2.3
1.9
88.10
94.54
pmol/l
0.59
26
165
27
173
1.76
1.62
2.0
1.9
526.18
452.81
pmol/l
0.37
22
150
20
117
1.88
1.59
1.2
1.2
1.16
8.30
u/ml
—
8
44
11
51
2.30
1.57
17.5
6.9
0.75
0.70
%
0.15
11
51
11
51
2.30
1.57
17.6
6.9
1.33
1.27
%
0.10
11
51
10
45
2.35
1.52
2.1
1.4
1.24
1.40
g/l
—
10
40
13
66
2.11
1.51
1.6
1.4
—
—
—
0
0
15
81
2.00
1.49
10.0
3.7
—
—
—
0
0
36
257
1.62
1.44
3.7
3.0
—
—
—
0
0
34
244
1.59
1.32
5.2
2.2
—
—
—
0
0
15
85
1.90
1.31
1.5
1.5
—
—
—
0
0
10
49
2.15
1.26
1.0
2.1
—
—
—
0
0
30
211
1.60
1.26
4.6
6.6
—
—
—
0
0
44
341
1.51
1.20
18.2
9.7
1.52
1.28
inr
0.66
16
103
31
223
1.56
1.18
3.2
3.1
—
—
—
0
0
11
59
1.97
1.12
5.6
5.1
0.00
0.22
%
—
6
23
8
41
2.03
1.11
1.3
1.5
—
—
—
0
0
32
236
1.52
1.08
3.9
3.8
7.41
7.41
ph
—
7
47
9
51
1.84
0.97
1.2
1.5
—
—
—
0
0
10
56
1.87
0.91
1.2
1.3
—
—
—
0
0
8
48
1.72
0.81
1.9
2.2
—
—
—
0
0
0
27
0.00
0.78
0.0
2.8
—
—
—
0
0
84
771
1.49
0.78
38.8
14.9
18.51
23.19
mg/l
1.39
78
621
13
84
1.63
0.76
1.5
1.3
—
—
—
0
0
37
300
1.36
0.73
4.8
3.8
11.31
77.60
e6/l
2.47
30
221
5
28
1.82
0.67
2.8
1.5
—
—
—
0
0
11
75
1.52
0.53
1.7
1.3
—
—
—
0
0
60
539
1.27
0.53
8.1
4.4
—
—
—
0
0
23
183
1.33
0.51
1.7
1.4
—
—
—
0
0
12
86
1.45
0.47
1.1
1.3
—
—
—
0
0
20
246
0.77
0.43
4.0
3.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
31
265
1.24
0.40
3.9
3.3
11.20
71.71
e6/l
1.16
26
205
7
54
1.32
0.31
1.7
1.5
—
—
—
0
0
8
62
1.31
0.29
4.5
3.5
—
—
—
0
0
8
64
1.27
0.28
2.3
1.8
—
—
—
0
0
84
812
1.19
0.22
39.9
17.4
85.25
82.26
umol/l
0.29
84
812
83
802
1.18
0.22
33.1
13.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
105.27
—
0
11
0
11
0.00
0.21
0.0
2.3
—
4.04
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
6
47
1.29
0.21
3.0
3.2
0.03
0.08
e6/l
—
6
47
55
529
1.09
0.11
5.3
4.2
—
—
—
0
0
17
155
1.12
0.09
2.5
3.4
2.48
2.46
mmol/l
0.22
17
133
65
667
0.93
0.09
27.0
15.7
39.35
39.89
%
0.17
41
468
6
74
0.80
0.08
1.8
1.3
—
—
—
0
0
32
305
1.07
0.07
2.7
2.0
—
—
—
0
0
74
729
1.05
0.04
4.5
4.0
1.22
1.26
mmol/l
0.18
69
650
22
211
1.05
0.03
4.4
3.6
—
—
—
0
0
24
246
0.97
0.00
5.9
4.3
—
—
—
0
0
85
854
0.97
0.00
48.0
21.8
29.99
30.28
pg
0.73
85
837
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
5.25
—
0
8
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
6.24
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
13.10
—
0
6
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: R18_ABNORMAL_FINDI_BRONCHIAL_WASHI_NASAL_SECRE_PLEURAL_FLUID_SPUTUM_THROAT_SCRAP – Abnormal findings in bronchial washings nasal secretions pleural fluid sputum throat scrapings

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).