Benign neoplasm: Carotid body

CD2_BENIGN_CAROTIDBODY

hypopharynx cancer: A primary or metastatic malignant neoplasm that affects the hypopharynx.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D35.50&, D35.59& Hospital discharge: ICD-9 — 2275 Cause of death: ICD-10 — D35.50&, D35.59& Cause of death: ICD-9 — 2275 2 out of 7 registries used, show all original rules.	98
4. Check minimum number of events None	98
5. Include endpoints None	98
6. Filter based on genotype QC (FinnGen only)	98

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	CD2_BENIGN_CAROTIDBODY
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D355
HD_ICD_9	2275
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D355
COD_ICD_9	2275
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Carotid body based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Carotid body

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	527	324	199
Only index persons	492	306	186
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	56.26	58.33	52.76
Only index persons	55.32	57.80	51.23

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	98	59	39
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	53.73	52.16	56.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
86: Matched controls
861

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D35.59

ICD-10 Finland

Other paragangliom

+∞

72.4

D35.50

ICD-10 Finland

Carotid body

+∞

40.9

BDA10

NOMESCO Finland

Operation on carotid body

+∞

16.1

WX408

NOMESCO Finland

General anesthesy, balanced

5.6

12.3

153

102

Kela drug reimbursment

Diabetes insipidus

+∞

9.5

Z31.5

ICD-10 Finland

Genetic counselling

12.8

9.3

H02AB09

ATC

hydrocortisone; systemic

13.7

9.0

AA4CG

NOMESCO Finland

Extensive MRI examination of sella turcica with high intensity magnet

49.7

7.9

E23.00

ICD-10 Finland

Panhypopituitarism

49.7

7.9

8680/3-C75.5

ICD-O-3

Paraganglioma, NOS, of aortic body and other paraganglia

+∞

7.4

D35.30

ICD-10 Finland

Craniopharyngoma

+∞

7.4

9350/1-C75.2

ICD-O-3

Craniopharyngioma, NOS, of craniopharyngeal duct

+∞

7.4

D35.9

ICD-10 Finland

Benign neoplasm: Endocrine gland, unspecified

+∞

7.4

E27.5

ICD-10 Finland

Adrenomedullary hyperfunction

+∞

7.4

101

Kela drug reimbursment

Anterior pituitary hypofunction

24.8

6.8

JN5ER

NOMESCO Finland

PET-CT of receptors in whole body

75.2

6.5

D35.2

ICD-10 Finland

Benign neoplasm: Pituitary gland

29.0

6.3

DCB00

NOMESCO Finland

Excision of lesion of middle ear

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

55.79

62.67

4.6

1.3

0.2

—

nmol/l

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

48.93

59.00

4.6

1.1

2.9

4.4

nmol/l

0.45

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

61.92

31.73

4.5

1.2

—

nmol/l

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

61.92

31.73

4.5

1.2

—

(4035726)

5.63

11.86

1.2

1.4

—

(3018418) pH of Serum or Plasma

224

3.24

7.56

4.0

3.5

7.4

0.02

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

377

3.30

7.25

6.4

8.2

1.2

mmol/l

0.68

330

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

375

2.78

5.58

4.7

4.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.23

4.62

4.4

3.2

—

(40768804) Tissue Pathology biopsy report

315

2.39

4.30

2.3

1.9

—

(3035637) Corticotropin [Mass/volume] in Plasma

7.80

3.94

1.9

1.5

—

(3002256) Pathology report gross observation

2.76

3.82

1.5

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

12.65

3.81

2.3

1.0

54.5

49.8

nmol/l

—

(3003396) Base excess in Arterial blood by calculation

2.85

3.75

4.5

14.4

2.0

1.4

mmol/l

0.28

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

5.39

3.46

1.0

1.3

—

(3019060) Gas panel - Arterial blood

3.25

3.27

3.5

15.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

746

3.10

3.27

4.6

4.8

1.7

1.8

mu/l

0.29

681

(3023368) Bacteria identified in Blood by Culture

197

2.21

3.26

4.9

4.6

—

(3044640) Blood type and Crossmatch panel - Blood

249

2.11

3.14

1.8

2.5

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

7.89

3.10

1.3

1.1

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

10.43

3.01

2.2

1.0

8.6

12.4

ug/l

—

(40761536) Microorganisms panel - Urine sediment

2.77

2.86

2.6

3.9

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

4.20

2.85

1.9

2.3

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

146

2.17

2.73

3.3

3.2

106.7

109.2

ng/l

0.01

102

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

187

2.06

2.64

1.8

2.5

—

(42870588) Differential panel, method unspecified - Blood

263

1.96

2.61

4.3

5.6

—

(3026389) Candida sp identified in Specimen by Organism specific culture

7.45

2.58

1.4

1.1

—

(3000991) Gas panel - Venous blood

2.56

2.34

4.6

10.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

117

2.14

2.29

2.5

1.8

—

(40768797) Stomach Pathology biopsy report

2.21

2.24

1.2

1.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

328

1.83

2.24

2.8

2.5

73.8

76.7

nmol/l

0.26

290

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

257

1.86

2.23

2.4

2.8

50.4

53.9

u/l

0.36

243

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.65

2.20

4.8

8.4

24.8

25.1

mmol/l

0.08

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

200

1.89

2.14

2.9

3.1

1336.9

1153.4

ng/l

0.08

167

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

750

2.43

2.09

17.0

12.6

83.9

84.5

ml/min/173m2

0.10

606

(3032080) INR in Blood by Coagulation assay

291

1.78

2.00

8.6

8.3

1.2

inr

0.19

(3003694) ABO and Rh group [Type] in Blood

224

1.79

1.90

1.6

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

208

1.80

1.86

3.7

3.9

0.0

estimate

0.00

(3044889) 12 lead EKG panel

519

1.75

1.82

4.2

3.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.54

1.74

5.8

12.6

93.8

94.9

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.71

1.54

1.9

2.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.52

1.42

2.0

2.5

—

(3019198) Lymphocytes [#/volume] in Blood

413

1.55

1.32

5.2

6.1

1.7

1.8

e9/l

0.62

370

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

2.87

1.30

1.2

1.7

—

(3013115) Eosinophils [#/volume] in Blood

414

1.55

1.29

5.2

6.3

0.2

e9/l

0.19

368

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

310

1.55

1.28

4.1

3.7

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.33

1.27

4.5

23.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

161

1.65

1.22

3.3

4.5

17.8

21.0

0.53

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.58

1.16

1.0

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.58

1.16

1.0

1.5

—

(3006315) Basophils [#/volume] in Blood

402

1.50

1.15

4.9

6.0

0.0

e9/l

0.27

351

(3001604) Monocytes [#/volume] in Blood

402

1.50

1.15

4.9

6.0

0.6

e9/l

0.14

349

(40761511) CBC panel - Blood by Automated count

858

2.18

1.15

17.3

12.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

543

1.51

1.12

4.4

4.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

226

1.54

1.12

3.0

3.2

—

(3021589) Normoblasts [#/volume] in Blood

356

1.49

1.11

12.0

9.1

0.0

e9/l

0.50

281

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

131

0.50

1.09

1.4

—

(3037522) Nuclear Ab [Titer] in Serum

107

1.71

1.08

1.4

1.5

352.0

440.0

titre

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

149

1.61

1.07

1.5

2.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.75

1.01

2.3

1.6

—

(3009261) Glucose [Presence] in Urine by Test strip

401

1.44

0.99

3.9

3.6

0.0

estimate

0.00

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.30

0.95

1.8

1.4

0.2

g/l

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.74

0.93

2.3

1.5

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.22

0.93

1.8

1.4

1.1

1.2

g/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

396

1.42

0.90

5.3

5.0

0.0

estimate

0.00

(3026008) Bacteria identified in Urine by Culture

239

1.43

0.84

2.8

3.0

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.80

0.0

2.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.65

0.79

2.5

1.5

—

(3012544) pH of Venous blood

1.68

0.79

2.0

4.6

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

822

1.69

0.79

17.3

14.0

23.2

22.6

mg/l

0.06

636

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.78

0.0

1.6

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.78

0.0

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

395

1.36

0.76

3.9

3.6

0.0

estimate

0.00

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.61

0.72

2.3

1.9

5.1

5.7

ug/l

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.97

0.71

1.0

1.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

478

1.34

0.70

8.4

10.8

4.5

4.1

e9/l

0.54

414

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.90

0.69

1.4

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

287

1.34

0.65

3.8

3.5

17.2

29.6

ng/l

0.88

186

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.70

0.62

1.0

2.1

—

(3013512) EKG study

223

1.36

0.62

3.4

3.8

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.59

0.0

4.9

—

(3022145) Colonoscopy Study observation

1.49

0.56

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.52

0.56

1.2

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.52

0.56

1.6

1.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

120

1.40

0.50

2.0

3.1

0.8

0.7

ug/l

—

(3042936) Bacteria identified in Isolate by Culture

120

1.40

0.50

1.5

2.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.49

0.48

1.7

1.6

—

(3049717) Cytology report of Urine Cyto stain

1.59

0.43

3.2

2.8

—

(40761535) Cells panel - Urine sediment

1.41

0.43

4.0

3.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

179

1.30

0.42

3.3

5.1

—

(3019309) Folate [Moles/volume] in Red Blood Cells

124

1.35

0.42

1.6

700.9

1169.2

nmol/l

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.3

—

5.4

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

3.2

—

18.8

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.41

0.0

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.41

0.0

1.8

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.34

0.40

1.1

1.2

—

33.9

—

(3019225) pH of Specimen

1.33

0.38

3.3

5.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.36

0.38

1.2

1.5

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

807

0.79

0.37

4.8

4.7

2.6

2.8

mmol/l

1.21

742

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

788

0.79

0.36

4.4

4.2

1.5

mmol/l

0.36

725

(3000492) Spirometry study

1.41

0.36

1.8

1.4

—

(3022313) Gas panel - Capillary blood

1.42

0.36

2.8

4.1

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.66

0.34

1.5

1.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.70

0.32

11.9

5.7

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.35

0.31

4.6

3.5

5.1

5.0

kpa

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

745

1.23

0.30

6.3

5.3

39.1

39.6

mmol/mol

0.18

704

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.37

0.24

3.0

4.1

23.5

24.6

mmol/l

—

(3000494) Fungus identified in Specimen by Culture

1.26

0.22

1.6

—

(40758558) Short blood count panel - Blood

212

1.17

0.22

6.7

8.0

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

762

1.19

0.22

5.1

4.2

5.9

mmol/l

0.06

700

(3019150) Specific gravity of Urine by Refractometry

174

1.19

0.22

5.7

3.7

1.0

kg/l

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.5

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(4306422)

0.00

0.21

0.0

1.3

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

3.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.28

0.21

1.3

1.9

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

4.0

—

(4268621)

0.00

0.21

0.0

1.9

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

105.7

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

0.21

0.0

2.8

—

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.27

0.20

1.3

1.8

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

156

1.19

0.20

1.3

11.9

29.2

iu/ml

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.20

0.0

1.1

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.25

0.20

2.0

2.5

1.8

1.7

0.09

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.21

0.20

1.0

1.3

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

756

0.87

0.19

3.9

1.6

1.3

mmol/l

1.35

690

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

172

0.85

0.17

1.7

1.9

0.6

1.3

mg/l

—

138

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

792

0.87

0.16

4.5

4.3

4.6

4.7

mmol/l

0.51

732

(36660697) Celiac disease serology panel - Serum

1.12

0.15

1.3

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.21

0.15

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

287

1.12

0.15

3.4

3.1

—

(3012516) Albumin [Mass/volume] in Urine

201

1.12

0.13

3.1

3.2

8.5

69.0

mg/l

—

131

(3009542) Hematocrit [Volume Fraction] of Blood

753

1.11

0.10

16.3

14.8

39.1

40.2

0.49

585

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.17

0.10

1.4

1.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.12

0.10

1.0

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

552

1.08

0.09

3.2

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

215

0.91

0.08

2.0

1.7

1.4

1.3

mmol/l

0.13

187

(3017181) Myelocytes/100 leukocytes in Blood

0.77

0.08

2.2

4.1

—

1.3

—

(4010399)

1.08

0.08

2.1

1.3

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

143

0.90

0.08

1.5

1.3

9.1

u/ml

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

183

0.91

0.07

5.3

3.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

104

0.85

0.06

1.7

2.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

171

0.92

0.05

1.4

1.6

—

(1761868) Lipid panel - Serum or Plasma

299

1.05

0.04

3.1

2.7

—

(3018095) Leukocytes [#/volume] in Urine

289

0.96

0.03

3.7

3.6

13.4

42.8

e6/l

1.85

200

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

123

1.07

0.02

1.5

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

294

1.03

0.00

2.0

94.5

97.3

pmol/l

0.11

142

(3007164) IgA [Mass/volume] in Serum or Plasma

186

1.03

0.00

1.5

1.3

3.3

2.4

g/l

—

104

(36304419) Bacteria [Presence] in Urine

231

0.99

0.00

3.2

2.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

219

1.01

0.00

3.6

3.7

1.6

11.4

mg/mmol

2.81

137

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.4

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

19.7

—

1641.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.2

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

16.8

—

862.1

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.3

—

(4027681)

0.00

0.0

1.1

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

1.7

—

7.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.5

—

(3002179) Metamyelocytes/100 leukocytes in Blood

0.85

0.00

2.2

4.1

—

0.5

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.8

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.1

—

90.2

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

2.0

—

(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

3.2

—

96.2

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

2.6

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.4

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.1

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.8

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.5

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.2

—

35.7

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.91

0.00

1.7

2.2

—

(3025159) Blasts/100 leukocytes in Blood

0.84

0.00

2.2

4.2

—

0.5

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.01

0.00

1.6

1.9

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.6

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

2.2

—

(3021440) Promyelocytes/100 leukocytes in Blood

0.84

0.00

2.2

4.3

—

0.2

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

8.9

—

0.6

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.2

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3020650) Glucose [Presence] in Urine

0.00

0.0

1.3

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.4

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.2

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

2.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

0.3

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

6.7

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

1452.8

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.0

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.4

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.0

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(4024509)

0.00

0.0

1.2

—

(3022621) pH of Urine by Test strip

0.87

0.00

5.2

1.9

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_CAROTIDBODY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CAROTIDBODY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_CAROTIDBODY – Benign neoplasm: Carotid body

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Carotid body

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints