Benign neoplasm: Mediastinum

CD2_BENIGN_MEDIASTINUM_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D15.2& Hospital discharge: ICD-9 — 2125 Hospital discharge: ICD-8 — 2125 Cause of death: ICD-10 — D15.2& Cause of death: ICD-9 — 2125 Cause of death: ICD-8 — 2125 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D15
Name in latin: Neoplasma benignum mediastini

NAME	CD2_BENIGN_MEDIASTINUM_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D152
HD_ICD_9	2125
HD_ICD_8	2125
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D152
COD_ICD_9	2125
COD_ICD_8	2125
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Mediastinum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Mediastinum

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	117	67	50
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	50.04	50.28	49.73

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
105: Matched controls
1050

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D15.2

ICD-10 Finland

Benign neoplasm: Mediastinum

+∞

94.6

21250

ICD-8 Finland

Benign neoplasm of respiratory system, Mediastinum

+∞

20.5

GEB30

NOMESCO Finland

Mediastinotomy and excision of lesion

+∞

17.1

D38.3

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Mediastinum

186.7

15.9

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

9.6

14.1

GEC24

NOMESCO Finland

Thoracoscopic thymectomy

+∞

11.7

2125A

ICD-9 Finland

Benign neoplasm of respiratory and intrathoracic organs, Mediastinum

+∞

10.6

GD1AA

NOMESCO Finland

Thorax X-ray examination

3.7

9.2

313

WX408

NOMESCO Finland

General anesthesy, balanced

3.6

7.8

158

ZXC96

NOMESCO Finland

Robot assisted procedure

+∞

7.4

D15.0

ICD-10 Finland

Benign neoplasm: Thymus

+∞

7.4

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

4.2

6.9

R4110

NOMESCO Finland

Physiotherapy

3.3

6.8

164

WF003

NOMESCO Finland

Adjuvant radiotherapy

74.2

6.5

A04AA02

ATC

granisetron; systemic, transdermal

+∞

6.3

130

Kela drug reimbursment

Malignant tumour

+∞

6.3

EP1AE

NOMESCO Finland

Neck ultrasound examination

13.6

6.2

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(4035726)

9.63

17.68

1.5

1.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

421

4.00

11.38

6.7

5.8

1.2

mmol/l

1.81

369

(3032080) INR in Blood by Coagulation assay

349

3.50

10.09

7.3

8.0

1.2

1.3

inr

0.12

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

199

3.52

9.75

2.3

1.8

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

115

3.60

8.15

6.4

5.3

105.4

103.7

mmol/l

1.19

110

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

394

3.04

7.92

3.7

3.5

—

(3000991) Gas panel - Venous blood

3.97

7.62

7.1

8.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.88

7.52

6.0

9.0

—

(3044640) Blood type and Crossmatch panel - Blood

261

2.88

7.20

2.8

1.9

—

(3018418) pH of Serum or Plasma

255

2.87

7.10

4.0

3.1

7.4

—

(3002256) Pathology report gross observation

3.75

7.06

1.2

1.1

—

(42870588) Differential panel, method unspecified - Blood

297

2.70

6.44

6.3

5.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

4.09

6.34

5.8

6.3

24.9

25.1

mmol/l

0.07

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

3.28

6.14

7.4

6.2

5.3

5.4

kpa

0.18

(3023368) Bacteria identified in Blood by Culture

208

2.69

5.84

4.5

3.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

309

2.56

5.80

3.2

2.6

35.9

28.9

u/l

0.44

294

(40768804) Tissue Pathology biopsy report

314

2.42

5.15

2.3

1.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.68

4.50

1.7

1.5

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

3.48

4.40

9.6

7.9

24.2

25.0

mmol/l

0.41

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.93

4.06

5.0

2.8

244.7

234.5

u/l

0.14

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

3.36

3.97

2.8

1.8

2.2

2.9

ug/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

526

2.19

3.95

8.2

6.2

4.1

4.3

e9/l

0.33

449

(3019198) Lymphocytes [#/volume] in Blood

467

2.02

3.39

7.0

5.0

1.8

1.9

e9/l

0.35

405

(3037467) Urinalysis macro (dipstick) panel - Urine

639

2.12

3.29

3.4

4.1

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.05

3.03

1.9

5.3

23.7

24.9

mmol/l

0.85

(3006315) Basophils [#/volume] in Blood

463

1.91

2.94

7.1

5.0

0.0

e9/l

0.76

396

(3001604) Monocytes [#/volume] in Blood

463

1.91

2.94

7.1

4.9

0.6

e9/l

0.13

396

(3013115) Eosinophils [#/volume] in Blood

474

1.90

2.90

7.3

5.0

0.2

e9/l

0.89

408

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

197

2.02

2.80

3.6

78.6

97.6

ng/l

0.11

161

(3021589) Normoblasts [#/volume] in Blood

396

1.86

2.73

11.0

7.8

0.0

e9/l

0.49

311

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

123

2.20

2.70

1.9

1.6

—

(40761536) Microorganisms panel - Urine sediment

2.65

2.56

3.1

3.4

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.41

2.52

2.8

2.7

183.6

209.8

ng/l

0.10

(3012544) pH of Venous blood

2.26

2.49

2.4

4.7

—

(40758558) Short blood count panel - Blood

222

1.90

2.45

6.7

4.6

—

(3002032) Base excess in Venous blood by calculation

2.27

2.43

2.4

4.7

1.4

2.3

mmol/l

0.75

(3030905) Polymorphonuclear cells [#/volume] in Blood

4.31

2.40

4.6

3.3

3.9

4.4

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

4.31

2.40

4.6

4.2

56.9

59.4

—

(3045142) Bone marrow Pathology biopsy report

6.47

2.39

1.0

—

(3044889) 12 lead EKG panel

698

1.88

2.33

4.5

3.7

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

209

1.88

2.33

2.8

2.0

2.8

3.1

mg/l

0.27

184

(40760888) Immunoglobulin light chains.free panel - Serum

4.45

2.18

5.8

1.1

—

(3018095) Leukocytes [#/volume] in Urine

325

1.75

2.18

3.3

3.6

10.1

88.8

e6/l

1.63

225

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

108

973

2.43

2.10

19.8

11.3

20.9

21.2

mg/l

0.04

729

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.17

2.02

2.0

1.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.09

1.86

2.0

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.13

1.85

2.4

2.9

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.48

1.84

1.6

1.3

—

(3013707) Erythrocyte sedimentation rate by Westergren method

721

1.73

1.83

5.5

4.0

12.6

11.4

mm/h

0.34

654

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.45

1.77

1.3

1.1

—

(36304419) Bacteria [Presence] in Urine

235

1.70

1.75

3.1

2.9

—

(3000494) Fungus identified in Specimen by Culture

114

1.91

1.70

1.9

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.99

1.66

1.5

—

(3030467) Casts [#/volume] in Urine by Automated count

257

1.64

1.62

3.0

2.9

0.2

0.4

e6/l

0.87

179

(3002582) Erythrocytes [#/volume] in Urine

275

1.63

1.61

3.2

3.0

8.7

298.9

e6/l

0.64

205

(3021788) Differential panel - Synovial fluid

3.43

1.54

1.0

1.5

—

(4034850)

0.00

1.53

0.0

6.0

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

111

1032

2.47

1.52

22.2

13.4

74.8

77.3

umol/l

0.57

111

1032

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.82

1.45

1.5

1.2

—

(3019060) Gas panel - Arterial blood

2.19

1.43

4.0

3.8

—

(3007853) Bacteria identified in Skin by Aerobe culture

105

1.84

1.43

2.0

1.9

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

3.02

1.37

1.0

1.2

—

(3037756) Immunofixation for Serum or Plasma

3.02

1.37

1.6

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.85

1.30

1.4

2.4

—

(3026782) Osmolality of Urine

166

1.64

1.29

2.5

2.7

480.6

542.3

mosm/kgh2o

1.04

134

(3003694) ABO and Rh group [Type] in Blood

219

1.57

1.25

1.5

1.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

861

1.64

1.23

21.6

12.6

39.5

40.9

1.07

621

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

101

918

1.73

1.22

4.7

4.5

1.8

1.9

mu/l

0.77

838

(3004588) Protein electrophoresis panel - Serum or Plasma

2.03

1.21

3.8

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

103

1.76

1.21

1.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.38

1.20

1.3

1.6

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

1.18

0.0

4.6

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

2.05

1.15

5.4

3.1

4.0

4.7

pmol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.05

1.15

1.4

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

305

1.47

1.13

3.1

—

(3026008) Bacteria identified in Urine by Culture

252

1.49

1.10

2.5

3.3

—

(3000492) Spirometry study

1.78

1.07

1.5

1.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

152

1.55

0.97

2.3

3.0

4.2

2.6

e6/l

—

(4010399)

1.75

0.96

1.5

1.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.29

0.95

1.7

1.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

206

1.47

0.93

2.5

1.7

0.8

1.0

mg/l

0.39

157

(3019309) Folate [Moles/volume] in Red Blood Cells

171

1.51

0.93

1.9

1.7

1239.3

1128.7

nmol/l

0.25

130

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

104

969

1.66

0.92

4.7

4.6

6.1

6.0

mmol/l

0.29

888

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.05

0.88

1.3

1.6

—

(3020891) Body temperature

1.98

0.85

5.7

2.9

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.80

0.0

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

168

1.46

0.79

2.3

2.7

0.8

1.1

e6/l

0.21

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.22

0.77

1.2

1.0

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.72

0.76

1.6

1.4

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

923

1.47

0.74

18.5

10.5

82.9

80.0

ml/min/173m2

0.75

739

(46235355) HIV 1 and 2 tests - Meaningful Use set

136

1.47

0.72

1.3

1.8

—

(3049717) Cytology report of Urine Cyto stain

1.89

0.69

1.6

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

746

1.33

0.68

4.0

3.8

14.5

15.0

pmol/l

0.87

681

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

295

1.32

0.64

3.7

3.1

923.4

1224.3

ng/l

0.47

243

(3022145) Colonoscopy Study observation

1.54

0.64

1.3

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.62

1.8

1.1

0.0

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.62

1.8

1.1

0.0

g/l

—

(3045414) Leukocytes [Presence] in Urine

1.75

0.58

1.0

1.8

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.65

0.56

3.0

1.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

191

1.32

0.52

2.5

1.3

1.8

2.3

g/l

0.71

111

(40761511) CBC panel - Blood by Automated count

107

1027

1.49

0.51

16.9

10.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

102

1.42

0.50

1.7

—

(3025941) Bacteria identified in Stool by Culture

1.49

0.48

1.1

1.3

—

(3023520) Reticulocytes [#/volume] in Blood

1.44

0.46

2.1

2.3

82.8

63.5

e9/l

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

1.59

0.43

1.8

1.1

0.0

g/l

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.59

0.43

1.0

1.7

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

2.7

—

4.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

2.7

—

105.5

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

2.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

596

1.20

0.41

3.0

2.9

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.49

0.41

1.6

1.8

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

390

1.21

0.39

2.2

1.9

83.7

95.4

pmol/l

1.01

192

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.33

0.38

1.0

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

357

0.82

0.37

3.3

3.7

—

(1761868) Lipid panel - Serum or Plasma

346

0.82

0.36

2.7

3.1

—

(3021601) Nitrite [Presence] in Urine by Test strip

461

1.19

0.36

3.3

5.0

0.0

estimate

0.00

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.45

0.36

3.3

1.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

155

1.27

0.35

1.8

1.6

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.37

0.32

3.1

3.7

23.4

25.6

mmol/l

—

(40768797) Stomach Pathology biopsy report

131

1.26

0.29

1.3

1.2

—

(3029937) Albumin [Presence] in Urine by Test strip

226

1.19

0.28

3.5

3.9

0.0

estimate

0.00

(36660697) Celiac disease serology panel - Serum

1.23

0.26

1.0

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.20

0.25

1.3

1.8

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.23

0.22

3.4

1.4

231.6

334.0

ug/l

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

174

1.18

0.21

1.4

1.2

134.1

43.2

iu/ml

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.7

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

388

1.13

0.21

4.0

3.5

30.6

44.4

ng/l

0.37

272

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3037522) Nuclear Ab [Titer] in Serum

127

1.21

0.21

1.3

1.4

240.0

509.0

titre

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

213

1.16

0.20

2.8

3.3

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.20

0.0

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

158

1.16

0.17

1.2

0.8

12.4

u/ml

—

(3022621) pH of Urine by Test strip

1.14

0.16

1.6

2.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

1011

0.86

0.16

5.3

5.2

2.7

mmol/l

0.04

939

(3048689) Calprotectin [Mass/mass] in Stool

119

0.83

0.16

2.7

1.8

172.1

75.4

ug/g

—

100

(3019225) pH of Specimen

1.14

0.15

3.8

4.1

—

(21494755) Public health laboratory ask at order entry panel

0.79

0.15

1.1

1.4

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

179

0.88

0.13

2.4

2.3

1.1

0.7

ug/l

0.29

111

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

115

1.15

0.11

12.1

6.8

—

(3041096) Erythrocytes [Presence] in Urine by Automated

258

0.91

0.10

2.3

3.4

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

996

0.90

0.10

4.6

mmol/l

0.10

924

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.09

0.10

3.4

2.5

31.4

44.6

u/l

—

(3009261) Glucose [Presence] in Urine by Test strip

471

1.07

0.09

2.7

3.5

0.0

estimate

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.12

0.08

1.9

1.1

211.6

198.1

u/ml

—

(3017732) Neutrophils [#/volume] in Blood

1.03

0.08

2.0

2.4

3.4

3.7

e9/l

—

(3015736) pH of Urine

364

1.07

0.07

2.4

3.4

—

(40761535) Cells panel - Urine sediment

1.07

0.07

1.4

3.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

246

1.07

0.07

4.4

3.4

25.0

24.1

—

115

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

132

0.90

0.07

1.3

1.5

—

(3035350) Ketones [Presence] in Urine by Test strip

459

1.04

0.04

2.7

3.5

0.0

estimate

0.00

(3012516) Albumin [Mass/volume] in Urine

312

1.04

0.02

3.0

3.3

1924.4

45.1

mg/l

0.47

197

(3020682) Albumin/Creatinine [Ratio] in Urine

327

0.97

0.01

3.2

3.9

1.3

6.1

mg/mmol

2.48

204

(3042936) Bacteria identified in Isolate by Culture

129

1.01

0.00

3.5

1.9

—

(3013512) EKG study

295

1.02

0.00

3.1

4.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

196

1.02

0.00

6.7

4.7

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

991

0.99

0.00

4.4

4.6

1.4

1.5

mmol/l

0.72

921

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

949

1.01

0.00

3.9

4.2

1.3

mmol/l

0.13

874

(3020951) Lymphocytes/100 leukocytes in Cerebral spinal fluid

0.00

0.0

1.0

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.8

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

2.6

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.4

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

3.0

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.0

—

6.2

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

1.7

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.8

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(44806420)

0.00

0.0

1.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.1

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

2.7

—

13.8

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.6

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.02

0.00

4.8

4.7

44.5

46.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.95

0.00

1.4

2.0

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

7.6

—

1437.9

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(3012565) Volume of 24 hour Urine

0.00

0.0

1.2

—

2049.2

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

7.1

—

0.7

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.4

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.4

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.00

0.00

1.4

1.7

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

6.6

—

829.1

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

10.1

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.4

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

31.4

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1585.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

2.1

—

(44813793)

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.3

—

32.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

(4198724)

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.1

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.87

0.00

1.0

1.1

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.0

—

133.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.2

—

5.4

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.3

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.3

—

(4146454)

0.00

0.0

3.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MEDIASTINUM_EXALLC – Benign neoplasm: Mediastinum

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Mediastinum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints