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Traumatic spondylopathy

DOID Endpoint Browser PheWeb

M13_SPONDYLOTRAUM

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M48.3
  • Hospital discharge: ICD-8 — 7132
  • Cause of death: ICD-10 — M48.3
  • Cause of death: ICD-8 — 7132

2 out of 7 registries used, show all original rules.

88

4. Check minimum number of events

None

88

5. Include endpoints

None

88

6. Filter based on genotype QC (FinnGen only)

88

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M48
Name in latin
Spondylopathia traumatica

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 861 449 403
Only index persons 672 376 296
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 59.90 63.11 56.48
Only index persons 59.56 62.52 55.79

-FinnGen-

Key figures

All Female Male
Number of individuals 88 53 35
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 55.91 57.95 52.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
81
Matched controls
809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M48.3
ICD-10 Finland
Traumatic spondylopathy
+∞
79.9
63
*
M48.0
ICD-10 Finland
Spinal stenosis
132.3
26.5
27
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
44.1
20.8
25
8
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
37.8
14.6
18
6
M54.5
ICD-10 Finland
Low back pain
6.9
13.0
38
91
71320
ICD-8 Finland
Osteo-arthritis and allied conditions, Traumatic spondylopathy
+∞
12.8
12
*
N03AX12
ATC
gabapentin; oral
11.2
11.5
22
26
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
69.4
10.9
12
*
N02AX02
ATC
tramadol; systemic, rectal
5.0
10.5
48
182
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
30.5
10.2
13
5
N03AX16
ATC
pregabalin; oral
6.0
9.6
29
69
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
+∞
9.6
9
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
56.2
8.9
10
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
23.1
8.8
12
6
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
99.9
8.6
9
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.0
8.3
24
53
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
28.1
7.8
10
*
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
87.7
7.5
8
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
+∞
7.4
7
*
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
7.4
7
*
N06AX21
ATC
duloxetine; oral
8.9
7.3
15
20
M03BX02
ATC
tizanidine; oral
3.6
7.0
52
271
M54.4
ICD-10 Finland
Lumbago with sciatica
9.4
6.6
13
16
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
29.2
6.4
8
*
N05CD07
ATC
temazepam; oral
4.6
6.1
22
61

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023368) Bacteria identified in Blood by Culture
35
165
2.86
5.18
5.3
3.6
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
14
40
3.97
4.54
1.9
1.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
53
332
2.50
4.19
5.7
5.8
mmol/l
1.2
1.2
0.06
47
276
(3006315) Basophils [#/volume] in Blood
48
290
2.44
4.08
5.5
5.0
e9/l
0.0
0.0
0.05
43
249
(3001604) Monocytes [#/volume] in Blood
48
291
2.43
4.03
5.3
5.0
e9/l
0.6
0.6
0.51
43
249
(3045414) Leukocytes [Presence] in Urine
9
17
5.76
3.61
2.4
2.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
45
275
2.30
3.60
3.6
3.7
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
43
260
2.28
3.51
2.2
2.1
nmol/l
74.4
78.0
0.38
38
228
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
25
119
2.54
3.47
3.7
3.3
ng/l
1568.4
50.7
0.47
18
99
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
41
248
2.22
3.29
2.0
1.7
pmol/l
81.8
96.8
1.14
25
114
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
11
34
3.55
3.18
4.4
6.0
%
0.7
0.7
0.28
11
34
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
58
409
2.23
3.12
3.1
2.7
u/l
54.0
50.5
0.13
53
383
(3014007) Fractional oxyhemoglobin in Arterial blood
10
31
3.51
2.87
4.7
6.5
%
94.9
93.3
—
10
31
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
26
137
2.27
2.85
2.0
1.9
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
41
264
2.04
2.68
4.1
3.9
ng/l
44.9
52.1
0.09
28
199
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
10
34
3.19
2.50
4.6
6.0
%
1.4
1.3
—
10
34
(3013650) Neutrophils [#/volume] in Blood by Automated count
50
352
1.97
2.48
9.5
9.7
e9/l
4.4
3.9
0.77
45
307
(3044640) Blood type and Crossmatch panel - Blood
31
188
2.00
2.33
2.0
2.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
65
508
2.07
2.32
8.8
6.8
u/l
94.6
81.8
0.49
59
472
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
10
5.22
2.10
1.0
1.2
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
32
3.01
2.07
1.4
1.8
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
55
416
1.86
2.05
6.9
4.1
—
4844.8
—
0
12
(3042936) Bacteria identified in Isolate by Culture
17
86
2.21
2.01
2.1
1.9
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
15
72
2.31
2.00
1.2
1.3
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
6
16
3.94
1.97
2.0
1.1
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
40
277
1.81
1.96
12.9
8.3
inr
1.5
1.3
0.30
12
92
(3037467) Urinalysis macro (dipstick) panel - Urine
55
423
1.80
1.87
5.4
4.0
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
5
12
4.35
1.85
1.0
1.3
—
—
—
0
0
(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
30
195
1.82
1.78
2.3
2.1
u/l
119.8
319.4
1.36
30
183
(3018405) Lactate [Moles/volume] in Arterial blood
7
24
3.08
1.76
2.0
1.8
mmol/l
1.1
1.5
—
7
24
(3020891) Body temperature
7
25
2.95
1.69
2.0
2.9
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
18
100
2.01
1.69
3.7
2.4
e6/l
4.1
3.1
—
9
58
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
71
600
1.95
1.67
5.3
4.7
mu/l
1.6
1.9
2.07
66
526
(3030467) Casts [#/volume] in Urine by Automated count
28
182
1.79
1.65
4.4
2.6
e6/l
0.1
0.4
1.70
20
138
(3013139) Helicobacter pylori Ag [Presence] in Stool
8
32
2.65
1.64
1.3
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
30
200
1.76
1.62
5.7
2.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
26
166
1.80
1.62
9.1
7.4
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
58
464
1.73
1.62
5.7
3.8
mm/h
14.9
13.1
0.37
53
416
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
7
27
2.73
1.55
2.0
1.4
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
21
127
1.86
1.54
1.6
1.6
nmol/l
1085.8
1183.6
0.15
15
94
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
17
97
1.93
1.48
2.6
1.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
10
46
2.32
1.46
2.1
2.7
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
22
2.85
1.46
1.7
1.5
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
6
22
2.85
1.46
2.3
1.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
34
241
1.67
1.45
5.3
2.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
6
23
2.72
1.39
2.0
1.7
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
74
647
1.90
1.38
23.2
12.6
mg/l
23.4
25.0
0.14
63
505
(3000764) Benzodiazepines [Presence] in Urine
5
17
3.05
1.38
1.0
1.4
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
16
92
1.90
1.36
1.5
1.8
s
27.3
29.7
1.77
16
87
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
6
24
2.61
1.33
3.5
1.6
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
5
18
2.88
1.30
1.0
1.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
12
63
2.05
1.30
1.4
1.5
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
17
102
1.83
1.28
3.6
2.4
e6/l
0.9
1.5
—
8
59
(42870588) Differential panel, method unspecified - Blood
28
195
1.64
1.26
4.3
4.6
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
5
19
2.73
1.23
1.0
1.3
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
5
19
2.73
1.23
1.0
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
5
19
2.73
1.23
1.0
1.3
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
30
214
1.61
1.23
4.4
2.7
e6/l
35.6
370.9
0.57
22
165
(3004588) Protein electrophoresis panel - Serum or Plasma
8
38
2.21
1.22
3.5
2.6
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
58
483
1.59
1.21
4.5
4.2
pmol/l
15.1
15.2
0.03
52
424
(3035350) Ketones [Presence] in Urine by Test strip
40
307
1.56
1.20
6.9
3.9
estimate
0.0
0.0
—
6
58
(3000330) Specific gravity of Urine by Test strip
8
39
2.15
1.19
9.4
4.3
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
10
52
2.04
1.11
1.7
1.4
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
5
21
2.46
1.10
1.2
1.3
nmol/l
47.8
42.0
—
5
21
(4094501)
5
21
2.46
1.10
1.2
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
33
247
1.54
1.08
4.8
3.1
e6/l
65.1
79.1
0.13
24
173
(40761511) CBC panel - Blood by Automated count
76
685
1.80
1.07
15.6
11.9
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
28
203
1.56
1.05
3.5
3.2
ng/l
1143.1
1670.8
0.71
23
172
(46235355) HIV 1 and 2 tests - Meaningful Use set
11
61
1.92
1.04
1.5
1.5
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
40
315
1.49
1.03
8.5
5.4
estimate
0.0
0.0
—
8
57
(3009261) Glucose [Presence] in Urine by Test strip
40
315
1.49
1.03
7.0
3.9
estimate
0.0
0.0
—
7
57
(3011397) Hemoglobin [Presence] in Urine by Test strip
21
143
1.62
1.02
6.3
3.4
—
—
—
0
0
(40761535) Cells panel - Urine sediment
9
50
1.89
1.00
6.3
3.2
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
25
180
1.54
0.96
4.0
2.5
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
27
2.31
0.95
1.2
1.1
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
32
245
1.48
0.93
6.3
4.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
13
80
1.73
0.90
21.4
8.0
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
27
0.00
0.79
0.0
1.2
—
—
—
0
0
(3019225) pH of Specimen
9
53
1.78
0.78
6.0
5.0
—
—
—
0
0
(3022145) Colonoscopy Study observation
9
53
1.78
0.78
1.3
1.3
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
7
39
1.86
0.74
2.3
1.3
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
11
69
1.68
0.72
2.5
1.7
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
21
156
1.45
0.69
5.9
4.1
estimate
0.0
0.0
—
8
57
(1761482) Bacteria [#/volume] in Urine by Culture
5
27
1.90
0.69
8.8
5.2
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
70
1.65
0.69
3.1
1.8
—
—
—
0
0
(3000492) Spirometry study
7
43
1.68
0.68
1.7
1.7
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
69
629
1.45
0.68
4.4
4.7
mmol/l
6.1
5.9
0.31
59
562
(3022313) Gas panel - Capillary blood
5
28
1.83
0.67
2.0
4.4
—
—
—
0
0
(3044889) 12 lead EKG panel
54
474
1.36
0.66
4.2
3.7
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
17
122
1.49
0.66
6.9
5.3
—
—
—
0
0
(3019550) Sodium [Moles/volume] in Serum or Plasma
74
685
1.50
0.65
24.8
14.5
mmol/l
139.1
139.9
2.10
69
665
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
5
29
1.77
0.65
6.0
6.6
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
17
124
1.46
0.61
1.2
1.3
u/ml
5.7
0.7
—
6
31
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
21
0.00
0.61
0.0
3.8
—
33.1
—
0
13
(3023103) Potassium [Moles/volume] in Serum or Plasma
74
689
1.47
0.59
24.5
14.6
mmol/l
4.1
4.0
1.61
69
669
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
35
1.77
0.59
1.7
1.2
—
—
—
0
0
(3005322) IgE [Units/volume] in Serum or Plasma
6
36
1.71
0.58
1.0
1.1
u/ml
43.3
163.4
—
6
31
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
13
92
1.48
0.54
1.3
1.3
u/ml
1.1
7.0
—
7
40
(36660697) Celiac disease serology panel - Serum
6
39
1.58
0.54
1.2
1.2
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
9
64
1.45
0.53
1.6
1.4
—
392.7
—
0
22
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
69
641
1.35
0.50
4.9
4.4
mmol/l
5.0
4.7
1.82
63
576
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
41
358
1.27
0.47
3.2
2.8
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
68
635
1.31
0.43
4.8
4.4
mmol/l
1.5
1.5
0.16
60
564
(3012544) pH of Venous blood
8
60
1.37
0.41
2.7
2.9
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
0
17
0.00
0.41
0.0
2.6
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
35
1.45
0.40
3.6
3.8
%
56.8
43.9
—
5
35
(40768793) Breast Pathology biopsy report
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
12
155
0.74
0.37
1.2
1.2
—
—
—
0
0
(3009343) pH of Capillary blood
6
42
1.46
0.36
1.8
4.0
—
7.4
—
0
7
(3004119) Hemoglobin [Mass/volume] in Venous blood
6
42
1.46
0.36
3.0
2.8
g/l
136.8
126.4
—
6
42
(1761868) Lipid panel - Serum or Plasma
20
239
0.79
0.35
3.1
3.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
21
177
1.24
0.31
5.5
3.8
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
8
64
1.27
0.28
1.5
1.3
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
27
238
1.19
0.26
2.2
3.4
mmol/l
2.3
2.4
0.28
22
210
(3042631) Mycobacterium sp identified in Specimen
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.1
—
4.2
—
0
5
(4281824)
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3000991) Gas panel - Venous blood
6
49
1.24
0.20
6.5
5.2
—
—
—
0
0
(3013512) EKG study
22
195
1.17
0.20
5.1
3.9
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
51
1.19
0.20
2.3
4.1
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
64
614
1.16
0.19
5.2
5.6
mmol/mol
39.2
40.0
0.37
56
552
(3009542) Hematocrit [Volume Fraction] of Blood
62
594
1.15
0.18
22.2
13.1
%
39.3
39.5
0.06
38
427
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
69
666
1.17
0.18
5.4
5.0
mmol/l
3.0
2.7
1.76
63
597
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
70
1.16
0.17
2.6
3.2
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
17
192
0.86
0.17
2.2
2.9
mmol/l
7.1
7.5
0.10
12
154
(3022621) pH of Urine by Test strip
5
43
1.17
0.10
2.2
3.1
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
54
1.12
0.09
1.2
1.8
—
—
—
0
0
(3002256) Pathology report gross observation
9
87
1.04
0.07
1.4
1.2
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
63
618
1.07
0.05
4.3
3.9
mmol/l
1.4
1.3
0.78
55
543
(3012516) Albumin [Mass/volume] in Urine
17
181
0.92
0.05
2.4
3.0
mg/l
5879.6
36.1
—
8
111
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
63
619
1.06
0.04
19.3
12.2
ml/min/173m2
80.1
77.4
0.42
54
497
(40768804) Tissue Pathology biopsy report
26
270
0.95
0.04
1.4
2.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
20
195
1.03
0.00
2.8
3.7
mg/mmol
3.3
4.9
—
9
118
(3007164) IgA [Mass/volume] in Serum or Plasma
11
109
1.01
0.00
1.5
1.3
g/l
1.7
2.6
—
5
60
(21494890) Protein electrophoresis panel - 24 hour Urine
0
5
0.00
0.00
0.0
7.2
—
—
—
0
0
(3027456) Digoxin [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.9
—
0.7
—
0
9
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.0
—
285.6
—
0
5
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.4
—
91.2
—
0
5
(3004451) EKG impression Narrative
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
9
0.00
0.00
0.0
1.2
—
113.3
—
0
9
(4306422)
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011391) Calcitriol [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
2.1
—
18.9
—
0
9
(3016244) Insulin [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.4
—
10.1
—
0
5
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4268621)
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
5
52
0.96
0.00
1.6
1.7
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.2
—
5.6
—
0
5
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
6
0.00
0.00
0.0
1.5
—
6.3
—
0
6
(1617658) Protocol used for examination of sentinel lymph nodes
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
5
51
0.98
0.00
1.6
1.5
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
0
9
0.00
0.00
0.0
2.1
—
42.7
—
0
9
(3038026) Centromere Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023419) Bacteria identified in Sputum by Culture
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
8
0.00
0.00
0.0
1.5
—
136.2
—
0
8
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3017817) Protein [Mass] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
7.2
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
72
0.97
0.00
1.4
1.4
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3016038) Potassium [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.2
—
20.2
—
0
5
(3051611) Lipemic interference index of Serum or Plasma
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
8
0.00
0.00
0.0
1.1
—
102.6
—
0
8
(3051651) Icteric interference index of Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
7
77
0.90
0.00
1.1
1.2
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
0
9
0.00
0.00
0.0
5.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_SPONDYLOTRAUM and mortality.

Females

Parameter HR [95% CI] p-value
M13_SPONDYLOTRAUM 1.502 [1.12, 2.01] 0.006
Birth year 0.994 [0.99, 1.0] 0.184

During the follow-up period (1.1.1998 — 31.12.2019), 103 out of 278 females with M13_SPONDYLOTRAUM died.

Males

Parameter HR [95% CI] p-value
M13_SPONDYLOTRAUM 1.588 [1.09, 2.31] 0.015
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 217 males with M13_SPONDYLOTRAUM died.

Mortality risk

Mortality risk for people of age

years, who have M13_SPONDYLOTRAUM.

N-year risk Females Males
1 0.098% 0.327%
5 0.726% 2.047%
10 2.085% 4.789%
15 4.192% 8.912%
20 7.266% 14.514%

Relationships between endpoints

↥

Index endpoint: M13_SPONDYLOTRAUM – Traumatic spondylopathy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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