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This is a non-core endpoint: only basic statistics are computed.

General- and plastic-surgery devices associated with adverse incidents

VWXY20_GENERAL_PLASTIC__DEVICES_ASSOCIATED_W_ADVER_INCIDENTS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Y81
  • Cause of death: ICD-10 Y81

2 out of 7 registries used, show all original rules.

90

4. Check minimum number of events

None

90

5. Include endpoints

None

90

6. Filter based on genotype QC (FinnGen only)

90

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Y7|Y8[0-2]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 90 66 24
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 58.08 55.76 64.47

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
78
Matched controls
781
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Y81
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents
+∞
35.1
31
*
Y81.3
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, surgical instruments, materials and devices (including sutures)
+∞
25.4
23
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
18.9
23.2
38
37
Y81.2
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, prosthetic and other implants, materials and accessory devices
+∞
14.0
13
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.4
12.5
24
29
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
126.3
10.7
11
*
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
23.9
10.2
14
7
Y81.8
ICD-10 Finland
General- and plastic-surgery devices associated with adverse incidents, miscellaneous devices, not elsewhere classified
+∞
9.6
9
*
N03AX12
ATC
gabapentin; oral
5.9
8.6
26
61
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
100.5
8.6
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
11.1
7.7
14
15
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
+∞
7.4
7
*
HWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of mammary gland
+∞
7.4
7
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
22.6
7.3
10
5
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
+∞
6.3
6
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
14.1
6.3
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
113
5.57
14.30
2.1
1.6
—
—
—
0
0
25
80
3.94
7.10
2.0
1.6
—
—
—
0
0
36
179
2.69
4.72
5.1
4.2
—
—
—
0
0
26
126
2.50
3.47
4.1
3.3
379.5
82.7
ng/l
0.45
19
93
38
231
2.12
2.93
3.4
2.2
—
—
—
0
0
67
509
2.24
2.81
4.5
4.3
—
452.0
—
0
11
46
319
1.90
2.32
3.2
2.0
—
—
—
0
0
33
208
1.93
2.20
2.8
2.6
—
—
—
0
0
18
91
2.22
2.13
1.9
1.3
—
—
—
0
0
10
39
2.76
1.99
19.5
9.7
0.9
0.7
%
—
10
39
15
73
2.27
1.94
1.7
1.4
—
—
—
0
0
10
40
2.69
1.91
18.8
9.5
1.8
1.6
%
—
10
40
26
161
1.86
1.79
1.3
1.3
10.3
34.4
iu/ml
—
6
57
13
63
2.24
1.69
15.1
8.0
115.5
120.4
g/l
0.41
13
63
5
14
3.71
1.64
1.0
1.0
—
—
—
0
0
40
292
1.67
1.54
2.2
2.0
99.4
100.5
pmol/l
0.03
22
139
32
222
1.68
1.48
3.1
2.9
10.3
320.8
e6/l
0.54
26
170
30
206
1.68
1.43
3.2
2.6
0.3
0.5
e6/l
0.56
24
156
24
155
1.75
1.42
1.3
1.3
1.1
11.0
u/ml
—
8
53
49
383
1.61
1.40
5.3
5.6
0.6
0.6
e9/l
0.54
42
324
29
199
1.67
1.38
6.6
8.4
—
—
—
0
0
49
384
1.61
1.38
5.3
5.7
0.0
0.0
e9/l
0.76
42
326
9
43
2.21
1.35
2.6
4.4
—
—
—
0
0
37
274
1.59
1.30
3.5
3.2
34.6
46.9
e6/l
0.17
28
188
5
18
2.88
1.30
1.2
1.2
—
—
—
0
0
63
533
1.61
1.22
4.6
4.2
—
—
—
0
0
20
292
0.59
1.21
2.6
3.0
—
—
—
0
0
49
392
1.55
1.21
5.3
5.7
1.8
2.1
e9/l
0.37
44
340
24
162
1.66
1.21
3.9
3.8
—
—
—
0
0
35
261
1.56
1.18
5.7
5.3
—
—
—
0
0
49
395
1.53
1.15
5.3
6.0
0.2
0.2
e9/l
0.52
42
341
9
48
1.97
1.04
21.1
8.9
—
—
—
0
0
7
37
1.97
0.96
1.4
1.1
—
—
—
0
0
6
32
1.94
0.83
1.2
1.2
—
—
—
0
0
0
25
0.00
0.80
0.0
1.6
—
—
—
0
0
0
25
0.00
0.80
0.0
1.4
—
—
—
0
0
0
26
0.00
0.80
0.0
1.4
—
—
—
0
0
0
26
0.00
0.80
0.0
1.3
—
—
—
0
0
0
26
0.00
0.80
0.0
1.4
—
—
—
0
0
0
26
0.00
0.80
0.0
1.4
—
—
—
0
0
6
34
1.82
0.78
26.8
7.4
—
—
—
0
0
5
23
2.24
0.77
2.0
3.5
12.0
48.8
u/ml
—
5
23
25
189
1.45
0.76
1.1
1.3
0.5
1.3
u/ml
—
7
53
7
38
1.91
0.75
2.7
2.2
—
—
—
0
0
7
38
1.91
0.75
5.4
7.3
25.3
25.4
mmol/l
—
7
38
5
27
1.90
0.69
2.2
4.3
—
—
—
0
0
5
27
1.90
0.69
2.2
4.0
—
—
—
0
0
14
95
1.56
0.69
1.3
1.4
—
—
—
0
0
10
152
0.62
0.69
3.4
5.1
1.4
2.1
ug/l
—
10
135
5
29
1.77
0.65
1.2
1.2
—
—
—
0
0
34
280
1.34
0.62
3.0
3.6
—
—
—
0
0
40
338
1.33
0.62
7.7
9.8
0.0
0.0
e9/l
0.50
28
270
28
224
1.36
0.61
2.0
2.8
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
0
22
0.00
0.60
0.0
1.4
—
—
—
0
0
0
23
0.00
0.59
0.0
1.3
—
—
—
0
0
0
23
0.00
0.59
0.0
1.3
—
—
—
0
0
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
29
236
1.34
0.57
1.8
4.0
7.4
7.4
ph
—
6
47
6
37
1.66
0.57
3.2
3.8
3907.7
48.4
u/ml
—
6
32
71
755
0.72
0.54
4.7
4.5
1.5
1.5
mmol/l
1.07
65
697
11
75
1.53
0.53
1.0
1.1
—
—
—
0
0
12
85
1.48
0.50
46.1
20.6
—
1.6
—
0
12
63
578
1.30
0.48
4.6
4.3
14.0
10.9
mm/h
0.67
58
520
72
759
0.74
0.44
4.6
4.5
4.7
4.8
mmol/l
0.35
66
705
42
370
1.25
0.44
5.0
5.1
0.0
0.0
estimate
—
6
71
33
283
1.26
0.43
10.7
10.6
1.2
1.2
inr
—
9
85
8
58
1.42
0.43
1.5
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
4.9
—
20.6
—
0
8
0
15
0.00
0.41
0.0
5.5
—
—
—
0
0
15
116
1.35
0.40
1.7
1.4
1416.0
457.9
titre
—
5
29
42
373
1.24
0.40
3.3
3.8
0.0
0.0
estimate
—
6
68
20
163
1.29
0.38
3.1
1.7
1.8
1.0
mg/l
0.41
15
128
9
71
1.30
0.37
2.2
3.4
—
—
—
0
0
19
230
0.78
0.37
4.1
3.9
—
—
—
0
0
41
366
1.22
0.36
3.3
3.7
0.0
0.0
estimate
—
6
74
70
735
0.79
0.35
4.1
4.0
1.3
1.2
mmol/l
0.63
65
669
66
697
0.80
0.35
26.4
14.6
37.1
40.3
%
1.65
54
523
24
204
1.24
0.33
2.2
2.7
336.8
4422.5
umol/l
0.79
19
172
57
529
1.21
0.33
3.8
3.7
—
—
—
0
0
65
611
1.23
0.33
3.3
4.2
14.9
14.7
pmol/l
0.42
56
564
78
807
0.75
0.32
24.1
15.8
71.4
74.2
umol/l
0.67
78
807
8
61
1.34
0.29
1.4
1.4
—
—
—
0
0
12
145
0.80
0.23
1.7
1.9
—
—
—
0
0
5
41
1.23
0.22
1.0
3.7
3.9
4.7
pmol/l
—
5
35
10
123
0.79
0.22
1.5
1.6
—
—
—
0
0
18
207
0.84
0.22
1.3
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
5.1
—
0
7
10
122
0.80
0.20
2.9
3.0
0.8
0.8
mmol/l
—
10
114
78
757
1.23
0.20
22.9
13.7
32.6
19.7
mg/l
2.16
64
582
0
14
0.00
0.20
0.0
3.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
7
58
1.22
0.18
2.3
3.8
—
—
—
0
0
75
771
0.84
0.18
4.9
5.0
2.7
2.8
mmol/l
0.55
69
711
7
62
1.14
0.18
3.3
2.6
10.8
9.8
g/l
—
7
54
7
62
1.14
0.18
5.4
5.5
7.0
9.4
mmol/l
—
7
57
5
68
0.72
0.17
3.6
3.3
—
—
—
0
0
16
140
1.17
0.16
1.2
1.8
885.2
1155.7
nmol/l
0.73
11
108
6
76
0.77
0.16
1.3
1.5
—
—
—
0
0
10
83
1.23
0.16
3.4
4.8
1.0
1.0
mmol/l
—
10
75
7
86
0.80
0.15
1.6
1.8
—
—
—
0
0
11
94
1.19
0.14
2.1
1.3
—
—
—
0
0
73
714
1.12
0.10
4.5
5.1
1.7
1.9
mu/l
0.62
65
656
7
65
1.08
0.08
2.4
1.5
—
—
—
0
0
6
71
0.83
0.08
1.2
1.3
—
—
—
0
0
30
285
1.08
0.08
3.6
4.1
13.4
28.9
ng/l
1.34
19
193
10
112
0.88
0.07
1.4
1.2
—
—
—
0
0
18
193
0.92
0.07
2.5
4.3
0.0
0.0
estimate
—
6
70
8
91
0.87
0.07
1.6
1.5
—
—
—
0
0
75
738
1.10
0.06
4.7
4.5
5.9
5.9
mmol/l
0.01
66
682
16
168
0.94
0.02
4.0
4.4
—
—
—
0
0
20
192
1.05
0.02
2.8
3.1
30.6
389.1
mg/l
0.53
12
120
80
794
1.07
0.01
19.2
12.7
—
—
—
0
0
21
216
0.96
0.00
2.0
3.2
—
—
—
0
0
71
715
0.97
0.00
5.5
5.8
38.4
40.0
mmol/mol
1.04
64
670
20
205
0.97
0.00
2.8
2.9
6.1
7.5
mmol/l
0.97
14
171
17
174
0.97
0.00
1.5
1.5
1.7
2.8
g/l
—
9
100
20
204
0.97
0.00
3.6
3.9
4.9
8.8
mg/mmol
0.61
12
116
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
0.00
1.8
1.7
1.7
1.4
g/l
—
5
46
0
8
0.00
0.00
0.0
6.3
—
415.1
—
0
8
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
2.2
—
0
5
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
16.0
—
941.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
21.0
—
1789.8
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.0
—
104.0
—
0
9
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
3.0
—
3.9
—
0
9
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
3.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_GENERAL_PLASTIC__DEVICES_ASSOCIATED_W_ADVER_INCIDENTS – General- and plastic-surgery devices associated with adverse incidents

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).