≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback
info icon

This is a non-core endpoint: only basic statistics are computed.

Melanoma in situ of scalp and neck

Endpoint Browser

CD2_INSITU_MELANOMA_SCALPNECK_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D03.4&
  • Cause of death: ICD-10 — D03.4&

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ verticis cranii

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 76 25 51
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 70.48 71.86 69.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
70
Matched controls
700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
100.5
70
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
322.7
62.8
57
9
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
16.8
17.4
29
28
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
32.5
16.3
21
9
L57.0
ICD-10 Finland
Actinic keratosis
12.3
15.4
30
40
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
+∞
12.9
12
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
8.8
12.3
29
52
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
78.4
12.0
13
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
11.8
11
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
18.1
11.8
18
13
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
28.5
10.7
14
6
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
+∞
9.6
9
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
101.7
8.6
9
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
8.5
8
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
8.5
8
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
8.5
8
*
ZZR00
NOMESCO Finland
Flap of skin
28.7
7.8
10
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
15.7
7.7
12
9
S18
ICPC
Laceration/cut
4.2
7.4
48
237
130
Kela drug reimbursment
Malignant tumour
+∞
7.4
7
*
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
+∞
7.4
7
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
22.9
7.4
10
5
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
19.1
7.0
10
6
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
29.6
6.4
8
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
+∞
6.3
6
*
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
44
35
28.48
49.72
1.9
1.1
—
—
—
0
0
60
153
14.88
27.81
4.3
1.5
—
—
—
0
0
16
12
16.62
17.34
1.4
1.2
—
—
—
0
0
40
188
3.38
6.40
9.0
4.5
—
—
—
0
0
50
271
3.47
6.30
6.2
3.5
35.2
34.7
g/l
0.31
43
249
5
0
+∞
5.26
1.0
0.0
—
—
—
0
0
5
0
+∞
5.26
1.0
0.0
—
—
—
0
0
12
30
4.56
4.63
5.3
1.4
4.5
2.6
ug/l
0.47
12
22
19
68
3.39
4.52
1.6
1.3
573.3
723.6
titre
—
6
22
37
195
2.75
4.46
4.1
3.2
99.9
55.9
e6/l
0.37
28
149
41
228
2.73
4.44
4.9
3.6
305.2
115.7
e6/l
0.52
29
166
49
301
2.77
4.32
9.3
4.7
0.2
0.2
e9/l
1.16
41
259
47
287
2.67
4.13
9.0
4.8
0.7
0.6
e9/l
0.38
37
236
47
291
2.61
3.96
9.0
4.7
0.0
0.0
e9/l
0.37
38
243
33
173
2.60
3.92
3.8
2.7
—
—
—
0
0
47
293
2.58
3.87
9.2
4.8
1.8
1.9
e9/l
0.24
39
249
36
198
2.55
3.86
4.9
2.2
2.4
2.3
mmol/l
0.63
30
163
51
331
2.64
3.86
12.6
5.4
4.4
4.6
e9/l
0.38
39
283
9
17
5.85
3.63
1.0
1.1
—
—
—
0
0
46
291
2.47
3.57
8.7
5.9
1.2
1.2
mmol/l
0.62
41
254
12
39
3.47
3.25
2.8
2.1
10.7
10.5
g/l
0.05
12
31
41
257
2.29
3.12
12.8
8.5
0.0
0.0
e9/l
0.00
29
204
32
182
2.31
3.05
4.0
2.9
0.1
0.4
e6/l
1.43
23
136
8
17
5.12
3.01
1.5
1.3
23.3
19.6
s
—
8
17
20
92
2.59
3.00
1.9
1.3
2.4
3.1
g/l
0.86
14
46
31
179
2.24
2.81
4.3
2.6
0.7
0.8
ug/l
0.28
21
126
6
10
6.40
2.75
12.2
1.1
—
—
—
0
0
66
525
2.95
2.73
22.2
15.3
41.1
39.9
%
0.72
40
319
31
183
2.17
2.63
5.2
3.6
7.4
7.4
ph
—
5
32
60
460
2.45
2.62
3.3
4.0
15.4
15.2
pmol/l
0.18
50
399
12
46
2.91
2.50
4.6
1.3
—
—
—
0
0
28
165
2.10
2.35
1.9
1.7
1.6
1.3
mmol/l
0.65
21
128
8
24
3.60
2.25
1.0
1.4
—
—
—
0
0
14
62
2.54
2.24
5.6
6.5
8.4
11.7
mmol/l
1.12
14
57
11
43
2.82
2.21
1.1
1.2
—
—
—
0
0
11
44
2.75
2.12
1.2
1.4
—
—
—
0
0
55
424
2.08
2.11
5.2
4.1
—
—
—
0
0
12
51
2.61
2.07
1.1
1.4
—
—
—
0
0
57
453
2.03
1.91
4.9
4.1
14.4
12.8
mm/h
0.29
52
403
17
90
2.15
1.83
1.5
1.1
—
—
—
0
0
39
277
1.84
1.81
9.3
11.1
1.2
1.5
inr
—
9
71
16
83
2.18
1.81
1.4
1.3
—
—
—
0
0
28
181
1.87
1.74
2.7
2.0
—
—
—
0
0
5
14
3.74
1.64
3.6
1.9
—
—
—
0
0
11
51
2.35
1.59
1.8
1.3
—
—
—
0
0
11
52
2.30
1.53
2.8
1.5
370.5
402.5
nmol/l
0.15
11
47
7
29
2.55
1.43
1.0
1.1
—
—
—
0
0
22
140
1.80
1.41
10.3
4.4
—
—
—
0
0
5
17
3.07
1.38
3.0
3.9
—
—
—
0
0
10
48
2.25
1.34
3.7
3.2
—
—
—
0
0
27
185
1.71
1.34
5.2
4.3
—
—
—
0
0
70
631
2.38
1.32
5.8
5.0
4.4
4.3
mmol/l
0.30
61
575
5
18
2.90
1.30
1.4
1.7
—
—
—
0
0
39
299
1.63
1.25
5.2
5.2
0.0
0.0
estimate
—
8
45
30
217
1.63
1.20
5.6
4.4
—
—
—
0
0
68
611
2.07
1.20
4.9
4.5
1.4
1.3
mmol/l
0.67
57
548
66
584
1.99
1.20
5.1
4.7
2.2
2.0
mu/l
0.20
55
512
5
20
2.60
1.17
1.6
1.6
—
—
—
0
0
69
627
2.09
1.12
6.0
4.9
1.4
1.4
mmol/l
0.05
58
568
13
75
1.88
1.11
2.7
3.2
—
—
—
0
0
32
240
1.58
1.09
4.5
3.3
8.0
7.9
mmol/l
0.03
24
190
68
616
1.99
1.07
7.7
7.1
41.4
41.4
mmol/mol
0.01
58
572
39
307
1.56
1.07
4.4
4.0
0.0
0.0
estimate
—
8
40
11
64
1.84
0.92
9.4
3.5
—
—
—
0
0
25
185
1.52
0.87
3.6
3.3
—
—
—
0
0
37
299
1.46
0.84
4.5
3.9
0.0
0.0
estimate
—
8
45
15
99
1.64
0.83
1.2
1.7
—
—
—
0
0
22
163
1.49
0.76
5.0
4.4
0.0
0.0
estimate
—
8
43
7
39
1.87
0.75
1.0
1.2
—
—
—
0
0
9
57
1.66
0.74
11.9
9.8
—
—
—
0
0
16
111
1.56
0.73
5.6
3.9
—
—
—
0
0
30
240
1.41
0.69
5.1
3.3
49.4
72.0
mg/l
0.44
24
156
7
44
1.65
0.67
1.3
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
4.4
—
—
—
0
0
0
22
0.00
0.60
0.0
1.8
—
6.7
—
0
8
6
36
1.72
0.58
1.3
2.6
—
—
—
0
0
42
364
1.34
0.57
6.9
3.8
2.4
2.0
ug/l
0.46
33
317
9
60
1.57
0.57
1.8
1.3
—
—
—
0
0
21
164
1.39
0.54
3.8
3.6
—
—
—
0
0
31
259
1.33
0.53
5.6
4.2
10.3
9.2
mg/mmol
0.10
21
167
6
40
1.54
0.53
2.7
2.4
—
—
—
0
0
8
56
1.48
0.44
2.0
2.1
0.3
0.2
g/l
—
8
46
16
124
1.37
0.43
3.1
1.5
31.2
29.9
s
0.24
16
118
15
115
1.38
0.43
2.0
2.4
16.2
12.4
umol/l
1.47
15
105
0
15
0.00
0.41
0.0
2.7
—
—
—
0
0
67
637
1.44
0.39
18.6
13.4
—
—
—
0
0
18
145
1.32
0.38
4.6
3.8
—
—
—
0
0
35
308
1.25
0.38
2.6
2.0
83.8
95.7
pmol/l
0.68
20
156
27
232
1.25
0.35
4.3
3.7
—
—
—
0
0
17
139
1.29
0.32
1.2
1.2
—
—
—
0
0
7
52
1.38
0.32
2.4
4.4
—
—
—
0
0
13
103
1.32
0.30
1.8
2.3
27.5
21.4
%
1.07
13
93
8
62
1.32
0.29
3.1
3.2
—
—
—
0
0
13
105
1.29
0.27
1.9
2.4
2.2
2.2
g/l
0.06
13
97
18
152
1.24
0.27
1.3
1.8
342.1
421.7
pmol/l
1.42
13
118
5
41
1.23
0.22
20.2
9.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
1.7
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
27
292
0.88
0.15
4.7
4.2
40.9
56.5
ng/l
0.46
20
225
21
191
1.14
0.13
4.1
3.6
—
—
—
0
0
7
80
0.86
0.07
1.6
1.9
—
—
—
0
0
48
471
1.05
0.03
5.5
4.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
107.4
—
0
7
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
4.2
—
0
7
0
6
0.00
0.00
0.0
1.0
—
2.7
—
0
6
0
6
0.00
0.00
0.0
1.0
—
19.2
—
0
6
0
5
0.00
0.00
0.0
1.2
—
69.4
—
0
5
6
61
0.98
0.00
7.5
3.1
4.6
4.9
kpa
—
6
56
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
506.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1.7
—
0
5
5
54
0.92
0.00
2.8
1.9
116.4
145.4
ug/g
—
5
41
0
8
0.00
0.00
0.0
1.6
—
87.3
—
0
8
6
68
0.87
0.00
2.0
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_MELANOMA_SCALPNECK_EXALLC – Melanoma in situ of scalp and neck

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).