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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Testis

CD2_BENIGN_TESTIS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only males

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29.2&
  • Hospital discharge: ICD-9 2220
  • Hospital discharge: ICD-8 2220
  • Cause of death: ICD-10 D29.2&
  • Cause of death: ICD-9 2220
  • Cause of death: ICD-8 2220

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D29
Name in latin
Neoplasma benignum testis

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 159 - 159
Unadjusted period prevalence (%) 0.07 - 0.07
Median age at first event (years) 47.14 - 47.14

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
139
Matched controls
1390
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D29.2
ICD-10 Finland
Benign neoplasm: Testis
+∞
129.0
103
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
211.8
44.7
44
*
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
124.4
35.7
37
*
22200
ICD-8 Finland
Benign neoplasm of male genital organs, Testis
+∞
24.7
23
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
204.6
17.9
18
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
15.6
17.1
28
22
130
Kela drug reimbursment
Malignant tumour
+∞
17.0
16
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
17.0
16
*
KFA00
NOMESCO Finland
Exploration of testis
166.4
14.7
15
*
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
+∞
13.8
13
*
2220A
ICD-9 Finland
Benign neoplasm of male genital organs, Testis
+∞
13.8
13
*
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
+∞
12.7
12
*
JN4BD
NOMESCO Finland
Extensive body CT
10.9
12.6
24
26
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
11.6
11
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
11.6
11
*
116
Kela drug reimbursment
Prostate cancer
+∞
9.5
9
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
9.5
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.2
9.0
24
45
N02AA05
ATC
oxycodone; systemic
5.2
8.7
27
61
H02AB02
ATC
dexamethasone; systemic
29.5
8.6
11
*
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
84.2
7.5
8
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.3
7
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
42.1
6.8
8
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
6.3
6
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*
D29.4
ICD-10 Finland
Benign neoplasm: Scrotum
+∞
6.3
6
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
31
8.08
15.24
1.2
1.3
—
—
—
0
0
44
158
3.47
10.21
2.8
2.5
12.1
15.5
nmol/l
1.78
38
146
25
79
3.57
6.92
1.2
1.1
—
—
—
0
0
56
284
2.50
6.63
2.2
1.5
—
—
—
0
0
72
454
2.07
4.76
9.7
11.1
1.2
1.5
inr
2.02
25
109
53
309
2.07
4.24
5.0
4.1
—
—
—
0
0
41
221
2.15
4.00
2.8
2.1
2.6
2.9
e6/l
0.22
36
185
18
66
2.95
3.90
1.6
1.4
—
—
—
0
0
47
279
1.97
3.50
3.8
2.5
—
—
—
0
0
51
321
1.87
3.16
4.1
2.8
40.0
252.6
e6/l
0.53
41
244
52
334
1.83
3.00
5.7
5.2
—
—
—
0
0
54
362
1.74
2.66
4.8
3.1
97.2
79.5
e6/l
0.12
41
264
16
68
2.50
2.65
1.4
2.1
30.1
38.0
nmol/l
1.01
16
68
46
296
1.78
2.60
3.9
2.6
0.8
0.4
e6/l
0.33
37
214
6
11
5.62
2.56
1.2
1.3
—
—
—
0
0
45
292
1.75
2.46
7.3
2.9
7.4
7.4
ph
0.21
13
46
8
22
3.77
2.40
4.1
3.0
—
—
—
0
0
100
807
1.64
2.34
5.1
3.7
3.6
2.0
ug/l
0.41
88
725
37
238
1.72
2.07
5.6
5.2
—
—
—
0
0
21
114
1.97
1.99
1.9
1.5
—
—
—
0
0
10
39
2.67
1.96
3.4
1.7
—
—
—
0
0
70
536
1.55
1.93
5.1
5.5
1.7
1.8
e9/l
0.42
63
483
20
110
1.94
1.83
1.7
1.4
—
—
—
0
0
16
81
2.08
1.82
5.5
2.9
—
—
—
0
0
68
524
1.52
1.79
4.9
5.3
0.6
0.6
e9/l
0.01
62
465
70
545
1.51
1.75
4.9
5.6
0.2
0.2
e9/l
0.46
64
487
68
527
1.51
1.73
4.9
5.3
0.0
0.0
e9/l
0.43
62
475
98
820
1.51
1.71
4.1
4.1
—
—
—
0
0
29
184
1.70
1.70
1.9
2.0
31.4
29.7
s
0.75
29
178
75
601
1.47
1.59
10.5
6.5
4.4
4.5
e9/l
0.06
69
536
85
698
1.47
1.59
4.6
3.5
—
—
—
0
0
35
239
1.60
1.55
3.0
3.6
227.2
302.2
ng/l
0.14
28
188
52
392
1.49
1.48
2.6
2.3
178.3
175.0
ug/l
0.03
47
359
39
277
1.54
1.46
4.6
3.4
0.0
0.1
estimate
0.68
15
73
36
254
1.54
1.39
3.9
3.7
86.0
84.8
%
0.10
36
248
25
165
1.61
1.27
2.4
1.8
—
—
—
0
0
6
25
2.45
1.25
1.0
1.2
—
—
—
0
0
16
94
1.78
1.23
1.4
1.3
—
—
—
0
0
21
135
1.64
1.19
1.1
1.2
—
—
—
0
0
0
36
0.00
1.15
0.0
4.2
—
—
—
0
0
126
1149
1.47
1.14
17.0
12.5
32.4
26.4
mg/l
0.80
102
894
59
476
1.38
1.12
9.8
7.7
0.0
0.0
e9/l
0.48
50
388
8
41
2.00
1.10
2.4
1.8
1.8
2.4
ug/l
—
8
34
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
55
443
1.37
1.05
3.1
2.6
0.7
0.8
ug/l
0.55
36
288
30
221
1.44
0.95
1.7
1.7
1.7
1.2
mg/l
0.30
24
170
16
104
1.60
0.88
3.3
1.8
61.8
62.0
e9/l
0.01
11
77
28
369
0.71
0.88
3.1
3.7
28.0
232.2
mg/l
0.71
21
260
6
30
2.04
0.88
1.3
1.1
—
—
—
0
0
15
98
1.59
0.82
11.0
8.6
—
—
—
0
0
39
309
1.35
0.82
3.1
2.2
—
—
—
0
0
18
124
1.51
0.79
1.9
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
8
133
0.58
0.77
1.3
1.5
—
—
—
0
0
47
390
1.29
0.71
5.1
3.1
—
—
—
0
0
32
399
0.75
0.71
4.0
4.6
6.4
10.3
mg/mmol
0.46
23
282
9
139
0.63
0.64
2.1
2.5
6.9
9.3
ug/l
—
9
123
51
434
1.26
0.63
1.8
2.0
86.7
91.5
pmol/l
0.26
25
251
130
1229
1.32
0.63
17.6
11.7
—
—
—
0
0
8
49
1.67
0.63
1.9
2.3
—
—
—
0
0
115
1073
1.26
0.61
17.6
13.3
42.3
41.6
%
0.64
79
755
0
21
0.00
0.60
0.0
2.1
—
—
—
0
0
0
22
0.00
0.60
0.0
2.1
—
4.2
—
0
22
0
22
0.00
0.60
0.0
2.1
—
105.0
—
0
22
6
98
0.60
0.54
1.5
1.5
—
—
—
0
0
56
490
1.22
0.53
4.3
3.3
0.0
0.0
estimate
0.00
15
77
89
816
1.21
0.52
4.3
3.6
11.2
10.7
mm/h
0.16
84
743
56
492
1.21
0.51
5.4
4.5
0.0
0.0
estimate
0.00
15
79
28
227
1.28
0.51
3.6
3.0
—
—
—
0
0
7
45
1.58
0.49
2.0
1.7
—
—
—
0
0
16
121
1.36
0.46
2.6
2.8
1.8
1.9
mmol/l
—
10
91
29
344
0.81
0.43
5.1
3.9
—
—
—
0
0
27
224
1.25
0.42
5.7
4.1
—
—
—
0
0
56
502
1.18
0.40
4.3
3.3
0.0
0.0
estimate
0.00
14
69
8
61
1.33
0.40
6.6
3.5
—
—
—
0
0
9
124
0.71
0.36
1.8
1.4
—
—
—
0
0
32
277
1.19
0.34
4.0
2.9
—
—
—
0
0
14
110
1.30
0.33
1.3
1.5
—
—
—
0
0
26
223
1.20
0.30
4.1
3.5
—
—
—
0
0
8
64
1.26
0.28
18.3
18.7
—
—
—
0
0
25
218
1.17
0.25
1.8
1.8
1332.8
1194.8
nmol/l
0.14
18
167
15
124
1.23
0.25
2.5
3.1
—
—
—
0
0
9
77
1.18
0.25
5.3
4.0
5.5
5.1
kpa
—
9
72
5
37
1.36
0.24
6.6
2.5
—
—
—
0
0
12
97
1.26
0.23
3.8
3.3
—
—
—
0
0
19
164
1.18
0.21
1.4
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
22
193
1.16
0.21
2.1
1.3
2.2
2.9
g/l
1.24
12
119
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
6
49
1.23
0.20
10.2
2.5
—
—
—
0
0
6
49
1.23
0.20
10.0
2.6
—
—
—
0
0
6
50
1.21
0.20
1.2
1.2
—
—
—
0
0
6
50
1.21
0.20
10.0
2.5
—
—
—
0
0
6
51
1.18
0.19
10.0
2.5
—
—
—
0
0
6
51
1.18
0.19
10.0
2.5
—
—
—
0
0
28
252
1.13
0.19
1.7
1.8
423.0
27404230.9
pmol/l
0.50
22
208
15
129
1.18
0.17
1.7
1.9
—
—
—
0
0
28
255
1.12
0.16
1.4
1.2
—
—
—
0
0
9
78
1.16
0.15
1.6
1.3
—
—
—
0
0
103
1000
1.09
0.15
3.6
3.5
1.9
2.0
mu/l
0.74
93
893
110
1128
0.92
0.15
4.5
4.6
6.0
6.1
mmol/l
0.49
103
1013
112
1095
1.08
0.13
5.3
6.4
40.3
40.7
mmol/mol
0.21
104
1018
5
48
1.04
0.09
2.4
1.5
—
—
—
0
0
5
60
0.83
0.08
1.6
2.9
—
—
—
0
0
7
66
1.06
0.08
2.1
1.8
1.1
1.4
%
—
7
66
11
98
1.13
0.08
3.4
3.8
301.4
235.8
ng/l
0.15
11
90
9
83
1.09
0.07
1.1
1.6
—
—
—
0
0
8
94
0.84
0.07
5.9
3.5
—
—
—
0
0
119
1175
1.05
0.06
3.9
4.5
4.5
4.4
mmol/l
0.32
110
1085
127
1256
1.06
0.06
11.6
8.5
27.8
30.0
u/l
0.94
127
1198
118
1167
1.04
0.05
3.9
4.5
1.3
1.3
mmol/l
0.36
109
1070
113
1140
0.97
0.03
3.5
4.1
1.3
1.3
mmol/l
0.13
102
1043
77
761
1.02
0.02
2.9
2.7
15.3
14.9
pmol/l
0.61
71
667
119
1198
0.97
0.02
4.4
5.0
2.7
2.7
mmol/l
0.04
111
1102
44
447
0.98
0.01
2.4
2.9
—
—
—
0
0
48
485
0.99
0.00
3.4
3.7
48.6
55.7
ng/l
0.11
36
348
10
98
1.02
0.00
4.2
9.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.8
—
50.0
—
0
6
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
1.8
—
0
8
7
72
0.97
0.00
1.9
3.3
4.1
4.0
e9/l
—
7
58
0
5
0.00
0.00
0.0
4.8
—
9.1
—
0
5
7
71
0.99
0.00
6.9
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
444.9
—
0
7
0
7
0.00
0.00
0.0
1.9
—
91.9
—
0
7
0
7
0.00
0.00
0.0
2.0
—
14.7
—
0
7
0
8
0.00
0.00
0.0
1.6
—
4.0
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
6
63
0.95
0.00
5.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
146.3
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
7.5
4.1
62.5
85.9
ng/l
—
6
59
0
8
0.00
0.00
0.0
1.6
—
1.8
—
0
8
0
5
0.00
0.00
0.0
1.4
—
11.2
—
0
5
5
54
0.92
0.00
1.6
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
5.6
—
0
5
0
8
0.00
0.00
0.0
1.0
—
373.3
—
0
8

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_TESTIS_EXALLC – Benign neoplasm: Testis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).