Pediculosis and phthiriasis

AB1_PEDICULOSIS_AND_PHTHIRIAASIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B85
  • Hospital discharge: ICD-9 13[2-3]
  • Hospital discharge: ICD-8 13[2-3]
  • Hospital discharge: excluded ICD-9 1330A
  • Hospital discharge: excluded ICD-8 13[3-4]0
  • Cause of death: ICD-10 B85
  • Cause of death: ICD-9 13[2-3]
  • Cause of death: ICD-8 13[2-3]
  • Cause of death: excluded ICD-9 1330A
  • Cause of death: excluded ICD-8 13[3-4]0

2 out of 7 registries used, show all original rules.

118

4. Check minimum number of events

None

118

5. Include endpoints

None

118

6. Filter based on genotype QC (FinnGen only)

118

Control definitions (FinnGen only)

Control exclude
AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1345 425 908
Only index persons 1108 349 759
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.03
Only index persons 0.02 0.01 0.03
Median age at first event (years)
Whole population 22.48 24.94 20.92
Only index persons 22.02 24.94 20.68

-FinnGen-

Key figures

All Female Male
Number of individuals 118 36 82
Unadjusted period prevalence (%) 0.03 0.01 0.04
Median age at first event (years) 22.82 25.98 21.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
110
Matched controls
1098
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B85.3
ICD-10 Finland
Phthiriasis
+∞
40.1
36
*
1322A
ICD-9 Finland
Pediculosis and phthirus infestation, Phthirus pubis [pubic louse]
+∞
18.2
17
*
B85.0
ICD-10 Finland
Pediculosis due to Pediculus humanus capitis
+∞
17.1
16
*
13299
ICD-8 Finland
Pediculosis
+∞
17.1
16
*
13399
ICD-8 Finland
Acariasis, Other
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
13
38
3.72
4.03
1.2
1.2
—
—
—
0
0
27
140
2.20
2.96
3.0
2.0
—
—
—
0
0
35
221
1.83
2.19
7.2
6.6
—
—
—
0
0
41
289
1.64
1.70
8.7
6.3
—
—
—
0
0
15
77
2.09
1.68
1.1
1.2
—
—
—
0
0
34
229
1.68
1.67
3.1
2.0
—
—
—
0
0
17
92
1.99
1.66
1.6
1.8
—
—
—
0
0
42
301
1.61
1.62
5.7
3.1
6.9
133.6
e6/l
0.79
33
211
6
22
2.82
1.45
6.0
4.8
56.5
57.0
%
—
6
22
6
22
2.82
1.45
5.0
4.3
3.2
4.6
e9/l
—
6
22
33
230
1.60
1.41
5.3
2.5
—
—
—
0
0
13
68
2.02
1.39
2.6
3.0
—
—
—
0
0
38
275
1.56
1.39
3.0
2.4
—
—
—
0
0
13
71
1.93
1.25
4.3
5.7
2.5
1.5
mmol/l
0.39
13
71
33
437
0.66
1.20
2.7
2.6
—
—
—
0
0
20
129
1.66
1.15
3.3
1.9
—
—
—
0
0
30
216
1.52
1.10
7.5
4.3
—
—
—
0
0
18
114
1.68
1.10
1.4
1.5
—
—
—
0
0
5
21
2.44
1.10
12.6
1.4
—
—
—
0
0
66
555
1.43
1.09
5.3
3.6
—
7.1
—
0
9
29
208
1.52
1.09
1.2
1.2
2.2
1.1
u/ml
—
6
55
7
33
2.19
1.07
1.4
2.5
—
—
—
0
0
18
115
1.67
1.07
2.2
1.5
—
—
—
0
0
5
22
2.33
1.04
3.0
3.9
—
—
—
0
0
10
170
0.55
0.99
1.1
1.3
—
—
—
0
0
93
1003
0.66
0.99
4.5
4.6
3.1
2.9
mmol/l
1.28
88
950
28
204
1.49
0.97
3.4
3.0
—
—
—
0
0
71
616
1.38
0.92
5.6
3.7
—
—
—
0
0
16
235
0.63
0.91
4.1
3.5
—
—
—
0
0
56
469
1.37
0.90
7.9
6.7
0.2
0.2
e9/l
0.24
51
429
8
44
1.88
0.88
5.3
5.7
25.4
24.6
mmol/l
—
8
44
6
31
1.98
0.85
2.2
1.3
—
—
—
0
0
16
107
1.57
0.81
1.4
1.4
—
—
—
0
0
61
525
1.34
0.79
11.0
10.6
3.9
4.2
e9/l
0.68
56
471
14
92
1.59
0.76
22.2
23.2
—
1.4
—
0
18
7
39
1.84
0.74
1.1
1.2
—
—
—
0
0
7
117
0.57
0.72
1.9
1.8
—
—
—
0
0
5
26
1.96
0.71
1.8
1.2
462.2
148.0
u/ml
—
5
14
93
990
0.71
0.70
4.0
4.3
4.9
4.7
mmol/l
1.01
87
942
18
131
1.44
0.64
2.1
1.8
—
—
—
0
0
93
986
0.73
0.63
4.0
4.3
1.3
1.4
mmol/l
0.59
85
934
33
268
1.32
0.62
6.0
3.8
2.4
2.3
mmol/l
1.46
28
233
8
52
1.58
0.61
6.6
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
3.6
—
—
—
0
0
26
323
0.75
0.59
2.9
3.3
66.6
41.0
ng/l
0.28
16
198
6
37
1.65
0.56
2.5
1.9
—
—
—
0
0
36
300
1.29
0.56
1.9
1.8
109.2
94.3
pmol/l
1.03
19
164
10
67
1.54
0.51
8.6
6.5
—
—
—
0
0
22
177
1.30
0.44
3.0
2.6
—
—
—
0
0
22
177
1.30
0.44
2.0
1.7
—
—
—
0
0
8
56
1.46
0.43
8.4
1.3
—
—
—
0
0
8
56
1.46
0.43
8.4
1.3
—
—
—
0
0
8
56
1.46
0.43
8.4
1.3
—
—
—
0
0
16
123
1.35
0.43
2.6
2.4
15.1
15.0
umol/l
0.01
16
110
8
57
1.43
0.43
8.5
1.3
—
—
—
0
0
18
142
1.32
0.41
6.8
3.7
0.8
0.8
mmol/l
0.63
18
135
0
15
0.00
0.41
0.0
1.1
—
3.9
—
0
7
0
16
0.00
0.41
0.0
2.6
—
—
—
0
0
0
16
0.00
0.41
0.0
4.0
—
7.2
—
0
16
0
17
0.00
0.41
0.0
3.4
—
22.0
—
0
12
8
61
1.33
0.40
1.3
1.1
—
—
—
0
0
99
1028
0.77
0.40
14.2
11.7
—
—
—
0
0
24
283
0.81
0.36
1.3
1.4
—
—
—
0
0
19
155
1.27
0.35
1.4
1.3
25.5
30.3
iu/ml
—
5
53
98
940
1.25
0.35
15.7
12.7
42.2
41.8
%
0.22
80
762
23
193
1.24
0.34
1.3
1.3
3.1
2.3
g/l
0.24
11
132
45
406
1.18
0.32
12.3
9.0
0.0
0.0
e9/l
0.50
38
334
19
157
1.25
0.32
4.1
3.8
72.7
215.7
ng/l
0.70
14
118
51
466
1.17
0.31
3.8
2.9
0.0
0.0
estimate
—
9
71
9
118
0.74
0.29
1.4
1.5
—
—
—
0
0
50
460
1.15
0.27
5.3
4.1
0.0
0.0
estimate
—
10
79
86
895
0.86
0.26
4.6
5.1
38.2
39.7
mmol/mol
0.99
81
855
50
461
1.15
0.26
3.8
2.8
0.0
0.0
estimate
—
10
77
9
73
1.25
0.26
2.1
1.8
41.3
38.9
nmol/l
—
9
73
109
1106
0.81
0.26
22.3
18.2
140.3
141.6
g/l
0.35
109
1095
109
1105
0.82
0.25
22.2
18.0
91.1
90.7
fl
0.45
109
1094
109
1105
0.82
0.25
22.1
18.0
30.5
30.4
pg
0.05
109
1094
9
75
1.22
0.25
4.8
4.1
—
—
—
0
0
19
162
1.21
0.25
1.4
1.3
30.1
4.4
u/ml
0.83
11
72
5
37
1.37
0.24
1.6
1.2
—
—
—
0
0
93
960
0.85
0.23
3.6
3.9
1.5
1.4
mmol/l
0.61
87
911
24
271
0.86
0.23
1.7
2.5
0.6
0.7
ug/l
0.25
13
150
5
41
1.23
0.22
12.6
1.2
—
—
—
0
0
29
260
1.15
0.22
2.2
2.3
280.8
229.7
u/l
0.19
29
243
24
270
0.86
0.22
3.7
2.5
—
—
—
0
0
14
117
1.22
0.21
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
9.6
—
976.7
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
13.9
—
1579.5
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
0.3
—
0
7
0
14
0.00
0.20
0.0
1.1
—
5.7
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
8
71
1.14
0.16
9.8
2.9
—
—
—
0
0
103
1049
0.86
0.15
18.2
14.0
80.5
78.6
umol/l
0.28
103
1049
7
88
0.78
0.15
8.1
6.9
5.5
5.0
kpa
—
7
83
10
84
1.21
0.14
1.2
1.4
—
—
—
0
0
24
259
0.91
0.11
4.7
4.0
6.7
9.6
mg/mmol
0.24
17
171
5
48
1.04
0.09
9.8
7.4
0.7
0.7
%
—
5
48
6
55
1.10
0.09
1.3
4.3
4.9
4.7
pmol/l
—
6
49
5
60
0.83
0.08
1.2
1.2
71.2
155.3
u/ml
—
5
55
5
62
0.80
0.08
4.0
6.1
—
—
—
0
0
7
63
1.12
0.08
2.1
1.1
—
—
—
0
0
7
63
1.12
0.08
1.3
1.7
—
—
—
0
0
6
74
0.80
0.08
9.2
7.9
130.8
124.6
g/l
—
6
68
8
75
1.07
0.07
1.6
1.3
—
—
—
0
0
12
108
1.12
0.07
3.0
2.4
35.2
26.4
%
0.68
12
93
23
243
0.93
0.06
6.4
5.2
—
—
—
0
0
65
663
0.96
0.05
4.0
3.9
13.8
14.8
pmol/l
2.78
60
617
11
119
0.92
0.04
1.3
1.4
—
—
—
0
0
84
830
1.04
0.03
4.5
4.5
1.6
1.8
mu/l
0.85
79
774
68
670
1.04
0.03
3.7
3.3
—
—
—
0
0
81
817
0.97
0.01
21.0
15.0
13.8
13.5
%
0.41
81
807
36
361
1.00
0.00
3.6
2.7
330.4
133.4
ug/l
0.75
36
345
96
963
0.98
0.00
17.0
12.2
22.3
22.0
mg/l
0.03
74
751
33
334
0.98
0.00
2.5
1.8
—
—
—
0
0
24
239
1.01
0.00
4.8
3.0
0.0
0.0
estimate
—
9
78
24
241
0.99
0.00
3.2
3.2
48.1
69.6
mg/l
0.25
16
157
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
0.00
9.8
7.3
1.1
1.8
%
—
5
49
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
14.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
28.1
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
1.1
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
6.5
—
0
7
5
53
0.94
0.00
1.6
3.3
173.4
164.0
ng/l
—
5
45
9
92
0.98
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
30.2
—
0
6
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
695.6
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
3.1
—
3.9
—
0
8
0
8
0.00
0.00
0.0
3.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.4
—
—
—
0
0
34
340
1.00
0.00
8.2
6.7
1.1
1.1
inr
—
10
95
0
8
0.00
0.00
0.0
3.1
—
106.5
—
0
8
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.6
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_PEDICULOSIS_AND_PHTHIRIAASIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
AB1_PEDICULOSIS_AND_PHTHIRIAASIS 3.346 [2.54, 4.41] < 0.001
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 328 males with AB1_PEDICULOSIS_AND_PHTHIRIAASIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_PEDICULOSIS_AND_PHTHIRIAASIS.

N-year risk Females Males
1 No data 0.722%
5 No data 4.328%
10 No data 10.4%
15 No data 18.78%
20 No data 30.318%

Relationships between endpoints

Index endpoint: AB1_PEDICULOSIS_AND_PHTHIRIAASIS – Pediculosis and phthiriasis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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