Malignant neoplasm of meninges, excluding all cancers (controls excluding all cancers)

C3_MENINGES_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C70
  • Hospital discharge: ICD-9 1921|1923
  • Hospital discharge: ICD-8 192[1-2]
  • Cause of death: ICD-10 C70
  • Cause of death: ICD-9 1921|1923
  • Cause of death: ICD-8 192[1-2]
  • Cancer registry: Topography ICD-O-3 C70
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

130

4. Check minimum number of events

None

130

5. Include endpoints

None

130

6. Filter based on genotype QC (FinnGen only)

130

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Malignant neoplasm of meninges, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 130 82 48
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 60.73 57.70 65.91

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
26
21.78
48.11
1.6
1.2
—
—
—
0
0
25
45
6.64
13.98
4.2
4.7
24.5
25.3
mmol/l
0.40
25
45
26
57
5.45
11.79
5.0
4.5
—
—
—
0
0
65
316
3.11
9.29
2.5
1.6
—
—
—
0
0
57
277
2.88
7.88
3.3
2.0
—
—
—
0
0
72
396
2.83
7.86
16.0
8.0
0.0
0.0
e9/l
0.61
65
316
21
56
4.28
7.42
6.7
3.4
0.0
0.0
%
—
6
12
21
59
4.05
6.92
6.7
3.5
0.0
0.1
%
—
6
12
50
241
2.75
6.85
7.0
4.0
—
—
—
0
0
30
111
3.21
6.58
5.2
4.7
1.7
1.9
mmol/l
0.14
24
89
11
18
6.58
6.54
2.5
2.2
4.9
4.8
kpa
0.01
11
18
11
18
6.58
6.54
2.5
2.2
8.7
8.2
kpa
0.35
11
18
11
19
6.23
6.22
2.2
1.2
—
—
—
0
0
21
64
3.72
6.17
6.9
3.3
1.1
0.9
%
—
6
14
19
54
3.95
6.15
7.1
3.6
0.5
0.4
%
—
6
9
51
277
2.38
5.22
3.4
2.7
—
—
—
0
0
52
288
2.34
5.06
3.5
2.9
0.2
0.5
e6/l
1.02
43
204
32
142
2.66
4.99
3.5
1.9
—
—
—
0
0
68
432
2.20
4.68
10.9
4.5
1.2
1.2
mmol/l
0.50
63
387
8
8
10.55
4.58
1.8
1.0
—
—
—
0
0
67
427
2.17
4.53
7.1
3.3
34.3
35.7
g/l
1.46
62
398
16
50
3.51
4.51
5.1
5.9
94.7
92.8
%
0.86
16
50
38
198
2.30
4.15
7.1
2.1
2.5
2.4
mmol/l
0.81
33
161
62
396
2.08
4.05
13.4
9.2
1.3
1.4
inr
0.07
29
110
9
16
5.95
3.73
5.1
3.4
53.0
58.4
%
—
9
16
15
51
3.19
3.71
4.9
5.7
0.7
0.8
%
0.46
15
51
51
313
2.04
3.63
3.7
3.1
16.5
246.6
e6/l
0.55
42
232
35
188
2.18
3.51
9.0
3.7
—
—
—
0
0
47
288
1.99
3.31
8.3
3.2
7.4
7.4
ph
0.72
18
44
51
323
1.95
3.26
3.8
3.3
—
—
—
0
0
7
11
6.65
3.23
2.0
1.2
—
—
—
0
0
8
16
5.25
3.10
1.3
2.3
—
—
—
0
0
8
16
5.25
3.10
4.0
2.2
3.4
5.3
e9/l
—
8
16
54
368
1.80
2.64
4.1
3.8
185.7
75.8
e6/l
0.53
45
254
39
240
1.89
2.64
4.8
4.2
0.0
0.0
estimate
0.00
27
67
5
8
6.44
2.39
2.4
2.3
—
—
—
0
0
12
48
2.65
2.26
8.9
1.6
5.7
2.6
ug/l
0.55
12
35
89
1029
0.57
2.16
4.3
4.6
6.0
6.0
mmol/l
0.07
76
933
63
470
1.66
2.12
8.8
4.5
0.6
0.6
e9/l
0.60
57
398
34
214
1.80
2.11
10.0
4.8
—
—
—
0
0
47
326
1.69
2.08
2.0
2.0
130.7
219.0
u/l
0.58
47
310
63
472
1.65
2.08
8.8
4.6
0.0
0.0
e9/l
0.94
57
402
57
418
1.65
2.03
3.4
3.9
16.3
34.8
ng/l
2.76
47
296
8
28
2.98
1.89
3.4
2.3
—
—
—
0
0
63
482
1.60
1.85
8.9
4.7
1.7
1.8
e9/l
0.78
58
420
20
114
1.89
1.68
1.8
1.4
—
—
—
0
0
7
25
2.90
1.67
4.3
2.6
0.1
0.1
g/l
—
7
7
14
70
2.12
1.66
6.6
6.1
—
—
—
0
0
63
491
1.55
1.66
9.0
4.8
0.2
0.2
e9/l
0.75
58
424
22
345
0.56
1.65
2.2
2.8
8.0
7.2
mmol/l
0.36
17
285
44
316
1.59
1.65
8.6
4.9
—
—
—
0
0
85
973
0.63
1.60
5.9
6.2
41.2
40.3
mmol/mol
0.49
76
907
20
117
1.84
1.56
1.8
1.8
—
—
—
0
0
38
268
1.59
1.52
6.2
3.3
—
—
—
0
0
14
73
2.03
1.50
1.8
1.1
—
—
—
0
0
13
67
2.04
1.44
3.5
3.7
—
—
—
0
0
93
1036
0.64
1.41
4.0
5.1
2.7
2.7
mmol/l
0.27
81
952
24
353
0.61
1.38
3.3
3.7
21.3
9.1
mg/mmol
0.25
13
204
5
18
2.85
1.29
1.2
2.3
—
109.8
—
0
5
21
133
1.69
1.27
1.7
1.8
—
—
—
0
0
23
335
0.62
1.26
2.3
2.9
13.2
481.5
mg/l
0.94
15
195
6
26
2.37
1.20
13.0
2.0
8.0
260.9
u/ml
—
6
21
60
497
1.38
1.02
6.1
5.0
0.0
0.0
estimate
0.00
26
68
59
489
1.38
1.00
4.4
3.7
0.0
0.0
estimate
0.00
27
70
92
1006
0.71
0.96
3.5
4.6
1.5
1.5
mmol/l
0.07
79
921
60
504
1.35
0.92
4.3
3.7
0.0
0.0
estimate
0.00
27
66
88
964
0.73
0.86
3.3
4.1
1.3
1.3
mmol/l
0.05
78
876
30
229
1.40
0.81
2.0
1.7
1.2
1.1
mg/l
0.20
23
177
21
150
1.48
0.80
1.5
1.1
—
—
—
0
0
80
714
1.31
0.76
4.2
3.9
—
—
—
0
0
7
38
1.89
0.75
4.1
3.6
—
—
—
0
0
41
334
1.33
0.74
3.0
3.2
—
—
—
0
0
11
69
1.65
0.71
3.7
1.4
—
—
—
0
0
18
128
1.47
0.70
7.5
4.4
0.9
1.0
mmol/l
0.96
18
115
28
219
1.36
0.66
1.6
1.8
437.0
33708312.0
pmol/l
0.50
21
178
29
229
1.34
0.64
1.4
1.3
—
—
—
0
0
8
50
1.64
0.62
1.0
1.3
—
—
—
0
0
8
54
1.51
0.58
6.1
4.1
27.9
24.6
mmol/l
—
8
46
95
1011
0.78
0.57
3.6
4.6
4.7
4.6
mmol/l
0.21
84
933
19
143
1.38
0.56
3.5
2.5
12.5
12.8
umol/l
0.04
19
132
6
38
1.61
0.55
4.0
3.3
1.5
1.1
mmol/l
—
6
38
13
176
0.71
0.50
1.2
1.3
12.5
7.6
u/ml
—
7
60
5
81
0.60
0.47
1.4
1.4
—
—
—
0
0
5
32
1.58
0.42
2.2
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
2.9
—
606.3
—
0
10
14
106
1.36
0.41
1.4
1.2
—
—
—
0
0
5
35
1.45
0.39
2.2
3.6
—
—
—
0
0
77
716
1.18
0.38
5.1
4.3
—
—
—
0
0
6
43
1.41
0.35
1.0
1.5
—
—
—
0
0
105
1007
1.22
0.35
28.5
12.7
21.5
23.2
mg/l
0.29
96
772
6
46
1.32
0.33
1.3
1.9
9.8
16.0
nmol/l
—
6
41
92
963
0.85
0.32
5.4
4.7
2.2
1.9
mu/l
1.49
84
875
11
85
1.32
0.29
1.6
1.5
—
—
—
0
0
8
63
1.29
0.28
2.1
2.3
—
—
—
0
0
26
296
0.85
0.27
1.6
1.6
1.4
1.3
mmol/l
0.12
18
253
24
208
1.19
0.26
2.0
1.6
1201.9
1094.0
nmol/l
0.21
15
157
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
13
107
1.24
0.22
4.0
3.4
—
—
—
0
0
8
102
0.77
0.22
1.5
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
276.2
—
0
6
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1.6
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
92
892
1.11
0.16
26.2
13.8
39.2
39.5
%
0.13
59
632
82
791
1.10
0.16
4.8
3.9
14.8
14.9
pmol/l
0.01
75
721
108
1056
1.13
0.16
23.6
11.8
—
—
—
0
0
16
181
0.87
0.15
1.4
1.3
55.0
27.4
iu/ml
—
7
63
8
97
0.81
0.14
11.3
3.4
—
—
—
0
0
21
230
0.90
0.12
3.0
3.5
—
—
—
0
0
41
388
1.08
0.12
3.3
3.4
—
—
—
0
0
26
277
0.92
0.09
1.3
1.6
17.3
22.4
nmol/l
0.85
21
238
6
53
1.14
0.09
3.0
2.2
0.7
1.1
%
—
6
53
6
58
1.04
0.08
3.8
3.4
—
—
—
0
0
5
64
0.77
0.08
1.4
1.6
—
—
—
0
0
8
73
1.10
0.07
2.4
3.2
—
—
—
0
0
8
92
0.86
0.07
2.4
1.4
—
—
—
0
0
32
309
1.05
0.04
4.0
4.0
—
—
—
0
0
44
451
0.96
0.03
2.0
2.0
85.8
97.8
pmol/l
0.83
20
229
77
778
0.97
0.02
4.7
3.9
14.1
12.1
mm/h
0.38
71
711
19
183
1.04
0.01
1.1
1.3
2.1
2.5
g/l
0.66
12
99
11
107
1.03
0.00
1.7
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
13.3
—
0
6
6
68
0.88
0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
29.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_MENINGES_EXALLC – Malignant neoplasm of meninges, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).