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Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)

Endpoint Browser PheWeb

C3_OROPHARYNG_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C10
  • Hospital discharge: ICD-9 — 146
  • Hospital discharge: ICD-8 — 146
  • Cause of death: ICD-10 — C10
  • Cause of death: ICD-9 — 146
  • Cause of death: ICD-8 — 146
  • Cause of death: excluded ICD-9 — 1460A
  • Cancer registry: Topography ICD-O-3 — C10
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

169

4. Check minimum number of events

None

169

5. Include endpoints

None

169

6. Filter based on genotype QC (FinnGen only)

169

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 169 56 113
Unadjusted period prevalence (%) 0.04 0.02 0.05
Median age at first event (years) 64.23 61.26 65.70

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
50
Matched controls
498
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
47.8
38
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
388.8
34.5
31
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
710.7
34.3
30
*
WF002
NOMESCO Finland
Radical radiotherapy
563.2
30.2
27
*
A03FA01
ATC
metoclopramide; systemic, rectal
36.6
24.7
34
27
N02AA05
ATC
oxycodone; systemic
33.4
23.5
33
27
R4190
NOMESCO Finland
Nutritional therapy
68.7
22.6
25
7
8070/3-C10.9
ICD-O-3
Squamous cell carcinoma, NOS, of oropharynx, NOS
+∞
21.4
19
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
21.4
19
*
C10.3
ICD-10 Finland
Malignant neoplasm: Posterior wall of oropharynx
+∞
18.9
17
*
H02AB02
ATC
dexamethasone; systemic
250.2
17.7
17
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
16.6
15
*
UJC01
NOMESCO Finland
Scopy of lower throat
+∞
16.6
15
*
A04AA01
ATC
ondansetron; systemic, rectal
54.5
15.7
18
5
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
15.4
14
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
14.2
13
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
14.2
13
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
24.9
12.3
17
10
C10.0
ICD-10 Finland
Malignant neoplasm: Vallecula
+∞
10.8
10
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
8.2
10.7
31
83
XX3DW
NOMESCO Finland
Time consuming IT work
23.0
10.7
15
9
EBA15
NOMESCO Finland
Extraction of large number of teeth
27.0
10.5
14
7
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
34.2
10.4
13
5
C10.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oropharynx
+∞
9.7
9
*
GBB00
NOMESCO Finland
Tracheostomy
30.8
9.4
12
5
SAA03
NOMESCO Finland
Extended examination of mouth
6.4
8.8
34
124
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
18.9
8.8
13
9
WF003
NOMESCO Finland
Adjuvant radiotherapy
107.4
8.7
9
*
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
+∞
8.6
8
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
+∞
8.6
8
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
8.6
8
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
8.6
8
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
30.5
7.9
10
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
93.4
7.6
8
*
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
+∞
7.5
7
*
C10.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of oropharynx
+∞
7.5
7
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.5
7
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
7.5
7
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
7.5
7
*
R4110
NOMESCO Finland
Physiotherapy
5.6
7.1
25
76
A02BC05
ATC
esomeprazole; systemic
5.2
7.0
34
144
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
8.8
7.0
15
23
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
26.8
6.9
9
*
WX402
NOMESCO Finland
General anaesthesia
6.6
6.7
18
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
8.8
6.6
14
21
Z51.5
ICD-10 Finland
Palliative care
21.4
6.5
9
5
WW500
NOMESCO Finland
Blood transfusion
31.0
6.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
12.4
6.4
11
11
8070/3-C10.3
ICD-O-3
Squamous cell carcinoma, NOS, of posterior wall of oropharynx
+∞
6.4
6
*
A06AD11
ATC
lactulose; oral
6.2
6.1
17
38
R13
ICD-10 Finland
Dysphagia
13.5
6.1
10
9

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(4035726)
63
42
23.32
75.74
1.5
1.3
—
—
—
0
0
(3043109) Cytology report of Tissue fine needle aspirate Cyto stain
21
12
19.84
25.96
1.1
1.2
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
94
389
4.19
19.14
3.2
1.6
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
53
146
4.83
18.56
2.1
1.8
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
103
555
3.19
12.22
6.0
3.5
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
79
366
3.18
12.20
3.6
2.1
—
—
—
0
0
(3002256) Pathology report gross observation
37
105
4.23
12.11
1.5
1.1
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
115
683
3.14
11.10
14.4
6.3
e9/l
4.6
4.4
0.43
103
604
(3023368) Bacteria identified in Blood by Culture
74
348
3.00
10.88
5.5
3.8
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
11
11
10.63
9.64
1.5
1.3
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
28
77
4.16
9.46
1.7
1.4
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
11
12
9.74
9.08
1.5
1.2
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
60
279
2.78
8.69
3.1
2.0
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
48
204
2.89
8.17
3.0
2.0
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
40
154
3.09
8.10
2.4
1.5
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
11
14
8.33
8.08
1.7
1.2
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
11
15
7.77
7.64
1.1
1.1
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
45
191
2.85
7.63
2.2
1.7
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
98
618
2.39
7.11
13.8
5.7
mmol/l
1.2
1.2
0.56
87
533
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
34
129
3.05
7.01
1.9
1.7
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
12
20
6.38
7.00
1.7
1.2
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
90
555
2.33
6.77
8.8
10.3
inr
1.1
1.4
3.09
25
158
(42870588) Differential panel, method unspecified - Blood
70
395
2.32
6.40
5.6
5.4
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
33
131
2.89
6.25
2.1
1.6
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
11
19
6.12
6.19
1.7
1.2
—
—
—
0
0
(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain
10
16
6.58
6.02
1.0
1.0
—
—
—
0
0
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
16
41
4.21
5.86
3.3
3.9
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
28
106
2.97
5.75
4.2
2.1
ml/min/173m2
76.6
60.2
1.47
12
45
(40758558) Short blood count panel - Blood
55
302
2.22
5.20
11.9
4.4
—
—
—
0
0
(3013115) Eosinophils [#/volume] in Blood
94
638
2.07
5.07
5.8
5.2
e9/l
0.2
0.2
0.24
81
560
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
86
567
2.05
5.00
11.6
5.2
mmol/l
1.2
1.2
0.27
81
505
(3002179) Metamyelocytes/100 leukocytes in Blood
22
79
3.05
4.93
2.7
4.3
%
0.0
0.4
—
5
16
(3001604) Monocytes [#/volume] in Blood
91
615
2.04
4.92
5.8
5.2
e9/l
0.6
0.6
0.09
78
532
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
11
24
4.83
4.85
1.7
1.3
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
8
7
11.91
4.83
1.5
1.4
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
91
618
2.02
4.82
5.8
5.2
e9/l
0.0
0.0
0.05
78
535
(3013826) Glucose [Moles/volume] in Serum or Plasma
110
808
2.04
4.58
9.4
4.4
mmol/l
6.7
6.9
0.57
110
756
(3019198) Lymphocytes [#/volume] in Blood
91
627
1.98
4.54
5.9
5.3
e9/l
1.6
1.8
1.30
77
550
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
9
12
7.85
4.41
1.9
1.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
27
120
2.49
4.07
14.4
7.0
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
19
71
2.89
3.98
14.3
8.8
—
—
—
0
0
(3018418) pH of Serum or Plasma
57
348
1.96
3.92
6.5
3.5
ph
7.4
7.4
0.10
11
51
(3003694) ABO and Rh group [Type] in Blood
53
316
1.99
3.90
1.4
1.3
—
—
—
0
0
(3027946) Carbon dioxide [Partial pressure] in Arterial blood
34
171
2.24
3.89
14.7
6.6
kpa
5.4
5.2
0.84
34
163
(3027801) Oxygen [Partial pressure] in Arterial blood
34
171
2.24
3.89
14.7
6.5
kpa
13.3
11.5
1.49
34
165
(3003396) Base excess in Arterial blood by calculation
34
172
2.22
3.83
14.6
6.6
mmol/l
1.5
1.6
0.08
29
136
(3018677) aPTT in Platelet poor plasma by Coagulation assay
40
220
2.07
3.65
1.8
1.8
s
30.5
29.8
0.28
40
213
(3017181) Myelocytes/100 leukocytes in Blood
21
90
2.52
3.40
3.2
4.3
%
0.3
1.0
—
7
23
(3014111) Lactate [Moles/volume] in Serum or Plasma
26
125
2.28
3.29
15.8
5.8
mmol/l
1.1
1.4
1.50
26
118
(3023419) Bacteria identified in Sputum by Culture
9
19
4.94
3.28
3.4
2.4
—
—
—
0
0
(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
8
15
5.54
3.23
1.9
1.1
—
—
—
0
0
(44790047)
6
8
7.72
3.08
1.3
1.3
—
—
—
0
0
(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
6
8
7.72
3.08
2.0
1.1
—
—
—
0
0
(44806118)
6
8
7.72
3.08
1.3
1.3
—
—
—
0
0
(44790049)
6
8
7.72
3.08
1.3
1.3
—
—
—
0
0
(44790048)
6
8
7.72
3.08
1.3
1.3
—
—
—
0
0
(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
7
12
6.03
3.05
2.0
1.1
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
5
5
10.25
2.99
1.0
1.0
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
5
10.25
2.99
1.8
1.2
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
17
4.88
2.95
1.0
1.1
—
—
—
0
0
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
17
4.88
2.95
1.0
1.1
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
7
13
5.56
2.90
1.3
1.2
—
—
—
0
0
(3021440) Promyelocytes/100 leukocytes in Blood
19
85
2.39
2.83
3.2
4.4
%
0.0
0.1
—
6
20
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
5
6
8.54
2.76
1.8
1.2
—
—
—
0
0
(40763571) Iron/Transferrin [Ratio] in Serum or Plasma
30
164
2.01
2.76
2.8
2.4
%
21.3
23.8
0.37
21
145
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
16
67
2.53
2.72
1.2
1.2
iu/ml
123.3
97.0
—
6
22
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
26
136
2.08
2.69
1.4
2.0
%
2.4
1.7
0.95
20
116
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
17
74
2.44
2.68
1.7
1.6
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
9
25
3.74
2.61
1.2
1.6
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
7
16
4.51
2.50
1.6
3.5
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
26
140
2.01
2.49
1.4
1.2
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
5
155
0.30
2.43
1.0
1.6
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
17
78
2.31
2.40
20.9
7.9
mmol/l
24.9
25.0
0.10
17
69
(3021589) Normoblasts [#/volume] in Blood
74
552
1.61
2.34
14.5
7.9
e9/l
0.0
0.0
0.49
62
449
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
119
1352
0.60
2.32
4.2
5.0
mmol/l
1.5
1.4
0.60
113
1234
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
18
88
2.17
2.21
21.2
8.2
%
0.9
0.7
0.74
18
88
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
121
1363
0.60
2.15
4.3
5.0
mmol/l
4.5
4.5
0.05
115
1250
(3021879) Hepatitis B virus core Ab [Presence] in Serum
14
62
2.37
2.14
1.2
1.3
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
18
90
2.12
2.09
21.2
8.1
%
1.5
1.5
0.12
18
90
(40768806) Pleura Pathology biopsy report
5
10
5.11
2.08
1.0
1.1
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
7
20
3.60
2.08
1.6
2.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
38
2.73
2.05
2.2
2.2
u/ml
0.4
0.3
—
5
21
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
8
26
3.18
2.04
1.5
1.3
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
125
1392
0.61
2.01
4.5
5.6
mmol/l
2.6
2.6
0.13
117
1271
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
15
71
2.22
1.99
14.1
7.5
mmol/l
26.5
25.5
0.32
15
71
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
41
274
1.66
1.97
3.8
4.1
ng/l
43.0
511.1
2.13
35
227
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
19
102
1.97
1.85
1.6
1.4
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
13
60
2.26
1.83
1.4
1.3
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
113
962
1.53
1.80
4.9
3.6
pmol/l
14.5
15.1
1.44
105
854
(3003181) Sodium [Moles/volume] in Urine
8
30
2.75
1.75
1.8
1.3
mmol/l
78.1
72.3
—
8
24
(3012544) pH of Venous blood
25
152
1.76
1.68
3.9
3.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
21
122
1.82
1.64
4.7
3.0
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
21
124
1.79
1.56
1.8
1.6
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
118
1308
0.68
1.47
6.0
6.8
mmol/mol
39.4
41.1
1.29
111
1207
(3024891) Influenza virus A+B Ag [Presence] in Specimen
6
22
2.79
1.44
1.0
1.1
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
5
17
3.00
1.37
2.0
1.8
e9/l
2.9
5.5
—
5
17
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
10
47
2.20
1.36
1.6
1.5
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
36
255
1.52
1.35
4.7
4.1
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
51
390
1.44
1.32
3.1
2.9
e6/l
62.5
211.3
0.42
37
304
(3026008) Bacteria identified in Urine by Culture
49
372
1.45
1.31
3.1
2.9
—
—
—
0
0
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
5
18
2.83
1.29
2.2
2.9
%
54.2
60.0
—
5
18
(40760888) Immunoglobulin light chains.free panel - Serum
6
25
2.45
1.25
5.7
1.3
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
47
359
1.43
1.21
3.1
2.7
e6/l
0.6
0.4
0.17
34
270
(3017143) Hepatitis C virus Ab [Presence] in Serum
17
102
1.74
1.21
1.7
1.4
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
60
483
1.38
1.14
2.8
2.4
ug/l
188.2
159.9
0.51
55
438
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
30
212
1.50
1.14
3.1
2.8
e6/l
2.1
1.8
0.06
19
127
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
10
51
2.02
1.13
2.0
1.6
—
—
—
0
0
(3000492) Spirometry study
16
98
1.70
1.08
1.8
1.4
—
—
—
0
0
(3048929) Epstein Barr virus Ab [Presence] in Serum
5
22
2.31
1.04
1.2
1.1
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
56
452
1.36
1.04
3.7
3.2
e6/l
166.0
100.0
0.27
40
330
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
10
54
1.91
0.99
1.3
1.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
141
1314
1.44
0.97
30.1
12.8
mg/l
34.1
23.5
2.98
133
1018
(3004716) Salmonella sp identified in Stool by Organism specific culture
9
51
1.81
0.96
1.3
1.3
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
40
312
1.37
0.91
1.5
1.5
nmol/l
24.2
19.4
0.70
34
267
(3019309) Folate [Moles/volume] in Red Blood Cells
34
260
1.39
0.87
2.1
1.7
nmol/l
1267.7
1246.0
0.05
26
205
(3019060) Gas panel - Arterial blood
16
106
1.56
0.82
8.1
4.6
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
30
228
1.38
0.80
3.1
2.6
e6/l
0.5
1.1
0.77
19
141
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
56
470
1.29
0.77
2.9
2.9
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
40
490
0.76
0.77
2.6
3.2
mmol/l
8.2
8.0
0.07
34
408
(3020682) Albumin/Creatinine [Ratio] in Urine
43
520
0.77
0.75
4.2
4.0
mg/mmol
7.3
7.5
0.02
30
338
(3044889) 12 lead EKG panel
108
984
1.27
0.75
4.4
3.9
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
38
1.88
0.74
1.1
1.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
38
1.88
0.74
1.1
1.1
—
—
—
0
0
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
64
735
0.79
0.73
3.2
3.9
ug/l
1.7
2.0
1.00
57
655
(42529406) Shigella sp [Presence] in Stool by Culture
7
39
1.83
0.73
1.1
1.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
5
26
1.95
0.71
1.2
1.1
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
49
577
0.79
0.69
2.7
3.6
%
18.9
24.3
1.62
18
266
(4010399)
5
95
0.51
0.68
2.6
1.4
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
40
481
0.78
0.66
3.6
3.3
mg/l
1521.4
188.7
0.43
27
320
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
42
499
0.79
0.63
5.1
3.7
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
34
414
0.78
0.62
2.1
2.6
ug/l
0.8
0.8
0.19
22
277
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
(3020891) Body temperature
10
64
1.60
0.60
5.4
4.2
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
13
89
1.50
0.60
2.2
1.4
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
22
0.00
0.60
0.0
1.1
—
7.7
—
0
14
(36304419) Bacteria [Presence] in Urine
40
335
1.25
0.56
3.2
2.6
—
—
—
0
0
(40768443) Skin Pathology biopsy report
9
62
1.48
0.54
1.4
1.3
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
74
665
1.20
0.53
2.5
2.4
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
11
75
1.50
0.52
1.4
1.5
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
10
67
1.52
0.51
1.8
2.3
ug/l
325.2
959.5
—
10
62
(3013707) Erythrocyte sedimentation rate by Westergren method
105
980
1.19
0.47
3.5
3.9
mm/h
19.6
11.5
3.40
97
898
(3013139) Helicobacter pylori Ag [Presence] in Stool
5
82
0.60
0.47
1.2
1.3
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
7
50
1.42
0.45
5.9
4.5
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
114
1075
1.19
0.44
36.8
15.1
%
14.4
13.6
4.61
114
1052
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
6
91
0.65
0.43
2.2
1.7
—
—
—
0
0
(3027456) Digoxin [Moles/volume] in Serum or Plasma
5
31
1.63
0.43
2.0
3.1
nmol/l
0.7
0.8
—
5
22
(3009445) Proteinase 3 Ab [Units/volume] in Serum
8
57
1.42
0.43
1.0
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
13
171
0.74
0.42
1.1
1.2
—
—
—
0
0
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
92
857
1.16
0.40
4.0
3.2
u/l
79.0
52.1
0.47
87
788
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
62
562
1.16
0.38
1.9
1.9
pmol/l
94.0
92.3
0.11
29
288
(3007628) Bicarbonate [Moles/volume] standard in Venous blood
9
68
1.34
0.38
1.8
3.8
mmol/l
25.3
24.9
—
9
60
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
130
1350
0.84
0.38
3.6
5.0
mmol/l
6.1
6.2
0.15
122
1215
(3020564) Creatinine [Moles/volume] in Serum or Plasma
139
1435
0.82
0.38
34.6
15.3
umol/l
75.7
82.6
1.59
139
1435
(40761511) CBC panel - Blood by Automated count
135
1397
0.83
0.37
26.6
12.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
6
41
1.48
0.36
2.0
1.7
—
—
—
0
0
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
6
41
1.48
0.36
1.3
1.1
—
—
—
0
0
(1002224) Polysomnography panel
6
44
1.38
0.35
1.0
1.0
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
30
346
0.84
0.34
5.3
3.3
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
11
83
1.35
0.33
1.0
1.2
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
125
1202
1.15
0.31
5.7
4.5
mu/l
2.9
2.0
2.80
118
1077
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
18
216
0.81
0.30
1.3
1.3
iu/ml
9.7
31.9
—
5
74
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
131
1268
1.15
0.27
26.6
11.7
ml/min/173m2
82.8
76.7
2.57
112
1022
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
17
202
0.82
0.26
1.2
1.2
u/ml
47.0
8.9
—
5
70
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
55
591
0.90
0.23
4.1
4.1
ng/l
30.8
44.5
0.80
48
438
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
11
88
1.27
0.23
2.9
2.2
%
1.9
1.2
0.75
11
88
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
5
39
1.29
0.23
2.0
1.4
—
—
—
0
0
(4027681)
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3051593) INR in Capillary blood by Coagulation assay
0
11
0.00
0.21
0.0
6.9
—
—
—
0
0
(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
10
0.00
0.21
0.0
1.2
—
8.0
—
0
10
(3044242) Glucose [Moles/volume] in Arterial blood
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3016914) Bacteria identified in Cerebral spinal fluid by Culture
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
44
476
0.90
0.21
3.5
3.2
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
0
13
0.00
0.21
0.0
1.0
—
1.2
—
0
8
(3003740) Influenza virus B Ag [Presence] in Specimen
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3011648) Oxygen content in Venous blood
0
14
0.00
0.20
0.0
1.8
—
12.0
—
0
14
(3022145) Colonoscopy Study observation
14
118
1.20
0.20
1.2
1.2
—
—
—
0
0
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
33
301
1.12
0.18
1.5
1.8
pmol/l
616.4
22984289.0
0.50
28
248
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
6
75
0.79
0.16
2.5
2.4
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
9
78
1.16
0.15
2.6
1.8
g/l
10.8
10.3
—
9
71
(3022313) Gas panel - Capillary blood
9
80
1.13
0.15
2.6
4.0
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
61
637
0.93
0.13
4.5
3.5
estimate
0.0
0.0
—
9
92
(3035350) Ketones [Presence] in Urine by Test strip
59
616
0.94
0.12
4.6
3.5
estimate
0.0
0.0
—
10
92
(3026493) Urate [Moles/volume] in Serum or Plasma
40
377
1.08
0.12
3.6
2.3
umol/l
345.6
9939.5
2.26
34
329
(3015736) pH of Urine
47
493
0.94
0.11
4.0
3.5
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
120
1177
1.07
0.11
31.4
13.7
%
37.3
40.0
2.19
80
783
(3049717) Cytology report of Urine Cyto stain
5
48
1.04
0.09
2.8
1.7
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
23
246
0.92
0.08
1.3
1.2
u/ml
2.0
1.8
—
8
64
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
19
176
1.09
0.08
8.8
7.2
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
61
628
0.96
0.07
6.1
4.9
estimate
0.0
0.0
—
9
95
(3000330) Specific gravity of Urine by Test strip
9
88
1.02
0.07
5.7
3.8
—
—
—
0
0
(3019225) pH of Specimen
13
120
1.09
0.05
4.1
3.0
—
—
—
0
0
(40761535) Cells panel - Urine sediment
11
118
0.93
0.03
2.4
3.1
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
89
881
1.02
0.02
4.4
3.9
—
—
—
0
0
(3013512) EKG study
44
448
0.98
0.01
4.5
4.1
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
32
326
0.98
0.00
4.8
3.6
estimate
0.0
0.0
—
9
90
(3007164) IgA [Mass/volume] in Serum or Plasma
21
213
0.98
0.00
2.7
1.3
g/l
2.9
2.7
—
10
119
(3011397) Hemoglobin [Presence] in Urine by Test strip
30
297
1.01
0.00
3.5
3.3
—
—
—
0
0
(3020951) Lymphocytes/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
64
0.94
0.00
1.0
1.0
—
—
—
0
0
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051101) Glucose [Moles/volume] in Cord blood
0
6
0.00
0.00
0.0
5.2
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(21491868) Cryoglobulin [Mass/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
5
58
0.86
0.00
1.2
2.5
u/l
39.6
39.8
—
5
52
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
12.7
—
1672.8
—
0
6
(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.0
—
1294.5
—
0
6
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
9
91
0.99
0.00
5.2
3.0
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
8
85
0.94
0.00
11.6
1.4
—
—
—
0
0
(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035999) Lactate [Moles/volume] in Cerebral spinal fluid
0
7
0.00
0.00
0.0
1.1
—
1.7
—
0
7
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3020717) Zinc [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
12.9
—
0
6
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
8.6
—
0.7
—
0
5
(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3022689) Creatine [Moles/volume] in Urine
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(44806420)
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(3006462) Nitrate [Presence] in Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
11.3
—
1179.0
—
0
6
(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum
0
8
0.00
0.00
0.0
1.0
—
10.2
—
0
8
(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(4211845)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3006653) Thiamine [Moles/volume] in Blood
0
7
0.00
0.00
0.0
1.0
—
170.5
—
0
7
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3003129) Base excess in Capillary blood by calculation
0
6
0.00
0.00
0.0
1.3
—
2.0
—
0
6
(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3045683) HLA typing for celiac disease panel - Blood or Tissue
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768793) Breast Pathology biopsy report
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(4024509)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006576) Bicarbonate [Moles/volume] in Blood
0
5
0.00
0.00
0.0
5.6
—
25.9
—
0
5
(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_OROPHARYNG_EXALLC – Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).