No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
94 |
4. Check minimum number of eventsNone |
94 |
5. Include endpointsNone |
94 |
6. Filter based on genotype QC (FinnGen only) |
92 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Chronic constrictive pericarditis
based on the number of shared cases.
Similar with more cases:
- Other diseases of pericardium
- Other heart diseases, wide
- Cardiovascular diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 92 | 25 | 67 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 64.55 | 67.64 | 63.40 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 94
- Matched controls
- 940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I31.1
ICD-10 Finland
Chronic constrictive pericarditis
+∞
135.4
94
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
18.4
38.5
37
32
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
15.6
32.7
34
33
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
159.0
32.0
32
*
I50.9
ICD-10 Finland
Heart failure, unspecified
10.3
29.9
57
122
B01AA03
ATC
warfarin; systemic
10.1
28.9
61
145
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
9.0
25.7
48
98
C03CA01
ATC
furosemide; systemic
10.4
23.9
75
258
I50.0
ICD-10 Finland
Congestive heart failure
9.4
21.6
32
49
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.2
17.6
50
146
ZXE20
NOMESCO Finland
More than three and less than five hours
6.6
17.5
39
91
I48
ICD-10 Finland
Atrial fibrillation and flutter
6.1
17.5
55
176
C03DA01
ATC
spironolactone; oral
6.5
16.1
35
79
C01AA05
ATC
digoxin; systemic
7.7
16.0
27
47
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
54.9
15.7
18
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
5.3
14.8
54
190
TFP20
NOMESCO Finland
Cardiodefibrillation
6.7
14.4
28
56
I34.1
ICD-10 Finland
Mitral (valve) prolapse
17.5
14.1
22
16
FEF10
NOMESCO Finland
Subtotal pericardiectomy
+∞
13.9
13
*
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
+∞
13.9
13
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
13.4
13.2
23
22
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
12.3
12.6
23
24
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.7
12.5
49
178
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
29.3
11.6
15
6
WX872
NOMESCO Finland
Intensive care
13.0
11.5
20
19
C07AB07
ATC
bisoprolol; oral
5.8
11.3
77
414
WX408
NOMESCO Finland
General anesthesy, balanced
4.3
11.0
44
159
201
Kela drug reimbursment
Chronic cardiac insufficiency
6.3
10.9
21
41
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
22.0
10.7
15
8
AN1
HP
Coronary angiography
4.8
10.6
30
83
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
10.5
70
362
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.9
10.3
22
31
207
Kela drug reimbursment
Chronic arrhythmias
4.4
10.0
34
108
ZXD05
NOMESCO Finland
Urgent procedure
4.0
10.0
47
189
I50.1
ICD-10 Finland
Left ventricular failure
9.5
9.8
20
26
I35.0
ICD-10 Finland
Aortic (valve) stenosis
5.5
9.4
21
47
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.7
9.2
26
71
R06.0
ICD-10 Finland
Dyspnoea
3.7
9.0
47
200
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
98.5
8.6
9
*
WX892
NOMESCO Finland
Monitored bed care
5.6
8.5
18
38
K78
ICPC
Atrial fibrillation/flutter
5.1
8.4
20
47
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
8.4
7.9
17
24
XF400
NOMESCO Finland
ECG with 12 standard connections
3.8
7.8
31
108
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
15.0
7.6
12
9
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.1
7.6
18
42
XF404
NOMESCO Finland
Ambulatory ECG
4.8
7.5
19
47
C07AB02
ATC
metoprolol; systemic
3.4
7.5
37
149
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
+∞
7.4
7
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
24.6
6.8
9
*
C01BD01
ATC
amiodarone; systemic
11.3
6.8
12
12
K83
ICPC
Heart valve disease NOS
74.7
6.5
7
*
AP3
HP
Catheterization of the right and left side of the heart
74.7
6.5
7
*
R18
ICD-10 Finland
Ascites
19.7
6.4
9
5
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
19.7
6.4
9
5
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.4
6.3
16
29
I97.0
ICD-10 Finland
Postcardiotomy syndrome
+∞
6.3
6
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.6
6.2
16
40
I50
ICD-10 Finland
Heart failure
8.2
6.2
13
18
B03XA02
ATC
darbepoetin alfa; parenteral
16.4
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
56
292
3.27
7.33
6.8
3.6
3759.42
1468.61
ng/l
1.17
50
241
33
125
3.53
7.30
4.4
2.2
22.11
22.88
%
0.10
27
110
32
136
3.05
5.71
3.3
4.0
0.81
0.82
mmol/l
0.20
32
128
66
419
2.93
5.46
47.9
15.7
2.02
1.24
inr
2.60
17
109
35
193
2.30
3.49
2.8
2.0
3.61
3.28
mg/l
0.28
29
172
9
21
4.62
3.08
2.2
1.1
—
—
—
0
0
9
23
4.21
2.86
3.2
1.3
—
—
—
0
0
27
144
2.23
2.85
5.6
3.5
1038.33
170.48
ng/l
0.63
27
123
67
790
0.47
2.55
5.1
5.2
2.28
2.65
mmol/l
2.97
62
712
10
32
3.37
2.52
2.5
1.8
45.20
36.51
u/l
—
10
27
25
138
2.11
2.39
4.0
2.1
32.27
29.47
s
1.81
25
133
22
365
0.48
2.34
3.0
4.6
27.64
20.72
%
—
8
192
52
375
1.87
2.27
12.4
7.8
1.18
1.21
mmol/l
2.73
45
319
62
743
0.51
2.27
6.0
6.5
39.86
41.04
mmol/mol
0.60
55
692
64
758
0.51
2.21
5.4
5.0
6.00
6.10
mmol/l
0.28
58
683
9
33
2.91
1.99
1.7
2.0
—
—
—
0
0
66
767
0.53
1.93
4.9
4.7
3.93
4.48
mmol/l
4.55
60
694
8
28
3.03
1.91
2.9
1.8
—
—
—
0
0
66
765
0.54
1.86
4.8
4.7
1.24
1.39
mmol/l
2.38
60
690
49
362
1.74
1.86
5.8
4.4
43.35
48.71
ng/l
0.14
37
269
7
24
3.07
1.76
1.0
1.1
—
—
—
0
0
5
13
4.00
1.74
1.6
1.2
—
—
—
0
0
26
167
1.77
1.57
1.7
1.8
1.25
1.70
mg/l
0.54
21
137
5
15
3.46
1.54
1.6
1.6
—
—
—
0
0
65
746
0.58
1.52
4.5
4.2
1.32
1.31
mmol/l
0.02
60
669
23
145
1.78
1.47
1.7
2.0
—
—
—
0
0
26
173
1.70
1.38
2.4
1.6
1299.78
1231.90
nmol/l
0.11
18
130
16
92
1.89
1.35
4.5
3.8
—
—
—
0
0
65
735
0.63
1.21
31.8
16.2
70.84
77.55
ml/min/173m2
1.18
57
603
75
818
0.59
1.13
36.4
20.0
109.07
85.11
umol/l
1.81
75
818
26
182
1.59
1.12
3.3
2.9
—
—
—
0
0
5
21
2.46
1.10
1.4
1.5
—
—
—
0
0
5
21
2.46
1.10
1.4
1.5
—
—
—
0
0
5
22
2.34
1.04
3.2
2.8
79.00
80.82
%
—
5
22
11
61
1.91
1.03
2.1
1.6
—
—
—
0
0
76
823
0.60
1.03
13.5
11.4
26.67
26.30
u/l
0.08
70
795
79
844
0.60
0.91
44.1
24.6
127.18
137.06
g/l
4.62
74
830
79
843
0.61
0.88
43.3
24.6
39.20
40.47
%
1.27
71
802
0
26
0.00
0.79
0.0
1.2
—
—
—
0
0
5
26
1.97
0.72
1.8
2.2
—
—
—
0
0
7
41
1.76
0.71
8.4
3.9
25.64
24.99
mmol/l
—
7
41
5
93
0.51
0.71
1.8
1.5
—
—
—
0
0
20
148
1.45
0.67
1.2
1.2
2.06
1.12
u/ml
—
7
49
8
50
1.65
0.63
1.6
1.8
—
—
—
0
0
5
30
1.70
0.62
1.8
2.7
—
—
—
0
0
0
21
0.00
0.61
0.0
2.0
—
—
—
0
0
0
21
0.00
0.61
0.0
2.0
—
—
—
0
0
16
116
1.46
0.59
6.5
7.3
104.00
103.89
mmol/l
0.04
16
116
0
23
0.00
0.59
0.0
1.2
—
—
—
0
0
34
397
0.78
0.52
2.6
2.6
—
—
—
0
0
38
326
1.28
0.50
4.9
3.2
—
—
—
0
0
39
337
1.27
0.48
5.0
3.0
—
—
—
0
0
14
104
1.41
0.46
1.7
1.7
—
—
—
0
0
68
630
1.29
0.46
9.8
8.2
99.18
80.27
u/l
1.02
60
589
14
105
1.39
0.44
1.2
1.3
1.82
9.17
u/ml
—
6
39
64
686
0.79
0.43
4.7
4.1
2.56
2.05
mu/l
0.80
55
603
18
142
1.33
0.42
2.1
2.7
6.60
1.71
e6/l
—
10
79
14
106
1.38
0.42
1.7
1.8
—
—
—
0
0
37
325
1.23
0.38
1.8
2.0
87.39
90.76
pmol/l
0.16
14
171
12
92
1.35
0.34
9.5
9.3
—
—
—
0
0
19
157
1.26
0.33
2.1
2.5
1.50
0.96
e6/l
0.25
11
92
50
462
1.18
0.28
7.8
10.9
4.38
4.32
e9/l
0.06
43
404
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
188.67
—
0
6
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
36
389
0.88
0.19
3.9
3.9
0.00
0.00
estimate
—
8
75
24
215
1.16
0.19
4.3
4.2
0.00
0.00
estimate
—
8
77
27
295
0.88
0.17
4.3
4.4
—
—
—
0
0
36
382
0.91
0.13
3.9
3.9
0.00
0.00
estimate
—
9
87
36
381
0.91
0.12
4.5
5.3
0.00
0.00
estimate
—
9
78
55
533
1.08
0.09
3.6
3.3
14.93
15.06
pmol/l
0.14
48
473
78
767
1.10
0.07
29.5
17.0
26.81
24.83
mg/l
0.22
67
629
79
801
0.91
0.06
38.9
19.6
4.07
4.02
mmol/l
0.98
72
780
30
289
1.06
0.04
2.6
2.3
59.57
78.67
nmol/l
2.66
25
250
79
798
0.94
0.02
38.6
19.5
138.82
139.70
mmol/l
2.25
72
777
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
57
570
1.00
-0.00
3.9
4.2
14.21
12.38
mm/h
0.53
52
520
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: I9_CHRONIC_CONSTRICTIVE_PERICARDITIS – Chronic constrictive pericarditis
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).