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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9)

CD2_BENIGN_INTRATHORACIC_NOS_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D15.7&, D15.9&
  • Hospital discharge: ICD-9 212[8-9]|2124
  • Hospital discharge: ICD-8 2124
  • Cause of death: ICD-10 D15.7&, D15.9&
  • Cause of death: ICD-9 212[8-9]|2124
  • Cause of death: ICD-8 2124

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Similar endpoints

List of similar endpoints to Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 93 45 48
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 53.42 53.98 52.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
87
Matched controls
870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.9
ICD-10 Finland
Benign neoplasm: Intrathoracic organ, unspecified
+∞
43.4
38
*
D15.7
ICD-10 Finland
Benign neoplasm: Other specified intrathoracic organs
+∞
37.2
33
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.1
12.6
26
35
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
8.5
32
95
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
8.5
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
7.6
46
203
130
Kela drug reimbursment
Malignant tumour
+∞
7.4
7
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.0
6.3
15
25
D15.1
ICD-10 Finland
Benign neoplasm: Heart
+∞
6.3
6
*
2129X
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Site unspecified
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
24
7.26
9.31
1.1
1.1
—
—
—
0
0
40
175
3.26
7.00
2.2
2.0
—
—
—
0
0
14
31
5.14
6.22
4.6
1.3
2.4
11.7
ug/l
0.52
14
25
15
40
4.28
5.33
3.1
1.7
0.2
0.2
g/l
0.04
15
33
43
223
2.73
5.25
2.2
1.5
—
—
—
0
0
45
258
2.44
4.27
11.1
9.2
1.2
1.3
inr
0.14
16
73
12
42
3.13
2.87
2.3
3.1
4.1
3.8
e9/l
0.23
12
31
17
74
2.59
2.78
5.8
5.2
1.1
1.0
mmol/l
1.36
17
67
9
24
4.04
2.75
2.2
6.3
—
—
—
0
0
27
146
2.20
2.75
7.3
5.1
—
—
—
0
0
14
57
2.71
2.59
1.2
1.0
—
—
—
0
0
17
83
2.28
2.18
2.1
1.5
—
—
—
0
0
43
297
1.83
2.13
13.6
7.9
0.0
0.0
e9/l
0.78
38
240
12
52
2.50
1.97
1.8
1.6
66.0
68.2
g/l
0.48
12
47
34
224
1.82
1.93
4.8
5.6
—
—
—
0
0
9
36
2.66
1.79
6.0
3.5
25.6
25.1
mmol/l
—
9
36
9
36
2.66
1.79
1.2
1.3
—
—
—
0
0
27
171
1.82
1.71
3.9
3.5
—
—
—
0
0
11
51
2.31
1.57
3.6
4.5
—
—
—
0
0
46
349
1.63
1.49
5.8
5.3
1.7
1.9
e9/l
0.49
41
306
13
67
2.09
1.47
1.4
1.4
—
—
—
0
0
47
360
1.62
1.46
5.6
5.7
0.2
0.2
e9/l
0.34
41
314
45
345
1.59
1.37
5.6
5.2
0.6
0.6
e9/l
0.20
39
300
45
346
1.58
1.35
5.6
5.2
0.0
0.0
e9/l
0.43
39
301
27
186
1.64
1.25
6.0
2.7
7.4
7.4
ph
—
7
26
17
104
1.78
1.19
1.9
1.5
—
—
—
0
0
11
58
2.02
1.18
1.5
1.3
—
—
—
0
0
8
40
2.09
1.15
2.5
5.5
—
7.4
—
0
5
6
27
2.30
0.95
1.2
1.2
—
—
—
0
0
59
506
1.45
0.93
4.9
3.8
—
—
—
0
0
8
42
1.99
0.91
9.4
2.7
1.2
1.2
mmol/l
—
8
32
19
130
1.58
0.90
2.1
1.7
1282.2
1120.6
nmol/l
0.36
14
99
36
284
1.44
0.88
4.8
3.8
16.9
43.8
ng/l
1.60
24
197
21
149
1.53
0.85
5.0
4.5
—
—
—
0
0
21
150
1.52
0.83
1.4
1.3
—
—
—
0
0
9
53
1.77
0.78
1.1
1.2
—
—
—
0
0
12
77
1.64
0.73
1.8
1.8
126.6
118.5
ug/g
—
7
61
45
381
1.35
0.69
8.9
6.3
4.1
4.1
e9/l
0.06
40
327
26
201
1.41
0.69
3.5
3.0
—
—
—
0
0
27
211
1.39
0.68
1.9
2.1
162.5
160.1
u/l
0.02
27
195
72
770
0.71
0.60
20.8
10.9
—
—
—
0
0
0
22
0.00
0.60
0.0
1.4
—
0.2
—
0
22
67
724
0.73
0.60
4.6
4.5
1.4
1.5
mmol/l
0.19
60
664
0
23
0.00
0.59
0.0
1.3
—
1.2
—
0
23
24
190
1.35
0.55
5.4
3.4
0.0
0.0
estimate
—
10
59
78
821
0.69
0.55
29.1
16.7
6.8
6.6
e9/l
0.36
78
791
78
821
0.69
0.55
29.0
16.7
4.4
4.6
e12/l
1.73
78
789
10
66
1.58
0.55
1.9
1.5
—
—
—
0
0
25
200
1.34
0.54
5.3
3.7
—
—
—
0
0
78
820
0.70
0.53
28.8
16.6
29.8
30.3
pg
1.74
78
802
78
820
0.70
0.53
28.9
16.7
90.3
90.8
fl
0.54
78
802
16
119
1.42
0.52
2.8
1.9
2.5
2.4
mmol/l
1.28
16
90
78
819
0.70
0.50
29.1
16.7
251.0
246.9
e9/l
0.23
78
791
7
46
1.56
0.49
3.0
2.0
9.4
10.4
g/l
—
7
41
67
717
0.77
0.48
4.8
4.6
5.8
6.0
mmol/l
0.78
61
648
8
56
1.47
0.44
7.1
2.8
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
1.4
—
0
15
0
16
0.00
0.41
0.0
1.9
—
7.8
—
0
7
0
17
0.00
0.41
0.0
2.7
—
—
—
0
0
66
703
0.79
0.41
4.0
4.0
1.2
1.3
mmol/l
0.20
61
642
5
34
1.50
0.41
4.6
3.9
0.7
0.8
%
—
5
34
5
34
1.50
0.41
4.6
4.0
1.0
1.5
%
—
5
34
11
80
1.43
0.40
1.7
1.4
—
—
—
0
0
27
228
1.26
0.39
2.5
1.8
56.5
56.6
u/l
0.00
20
209
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
5
36
1.41
0.39
1.4
1.5
—
—
—
0
0
11
82
1.39
0.36
1.3
1.4
—
—
—
0
0
69
727
0.80
0.34
4.7
4.5
4.6
4.6
mmol/l
0.27
62
670
23
194
1.25
0.34
4.0
3.2
—
—
—
0
0
8
63
1.29
0.29
4.2
2.8
132.6
145.7
ng/l
—
8
52
38
343
1.18
0.28
6.2
4.8
0.0
0.0
estimate
0.00
12
59
29
256
1.19
0.28
3.3
3.1
520.7
48.1
e6/l
0.71
24
166
12
96
1.29
0.26
1.3
1.1
—
—
—
0
0
11
88
1.28
0.24
4.6
2.5
18.4
25.7
%
2.02
11
78
5
38
1.33
0.23
2.4
2.6
—
—
—
0
0
5
38
1.33
0.23
2.2
1.3
0.9
1.2
g/l
—
5
33
38
348
1.16
0.23
4.8
3.5
0.0
0.0
estimate
0.00
11
58
21
183
1.19
0.23
3.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
106.3
—
0
10
0
10
0.00
0.21
0.0
2.0
—
4.2
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
72
746
0.85
0.21
5.0
5.0
2.6
2.8
mmol/l
0.58
63
682
0
13
0.00
0.21
0.0
2.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
62.5
—
0
13
6
49
1.24
0.20
1.3
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
7.8
—
0
14
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
6
51
1.19
0.20
4.3
4.0
—
—
—
0
0
7
61
1.16
0.18
7.1
4.9
119.0
122.3
g/l
—
7
61
7
62
1.14
0.18
1.3
1.8
—
—
—
0
0
67
694
0.88
0.17
5.8
6.1
38.6
40.2
mmol/mol
0.82
60
643
8
69
1.17
0.17
1.5
1.8
—
—
—
0
0
48
454
1.12
0.16
4.8
3.8
—
54.3
—
0
6
37
345
1.12
0.16
4.9
3.4
0.0
0.0
estimate
0.00
12
62
77
749
1.16
0.16
21.3
13.4
139.9
139.8
mmol/l
0.17
77
725
77
751
1.15
0.13
21.5
13.5
3.9
4.0
mmol/l
0.66
77
727
31
289
1.11
0.13
1.8
1.9
88.6
92.5
pmol/l
0.18
14
136
63
610
1.10
0.12
21.6
13.6
14.1
13.6
%
1.00
63
599
17
155
1.12
0.10
1.1
1.3
0.8
1.3
u/ml
—
8
37
13
117
1.13
0.08
1.2
1.4
34.2
17.8
u/ml
—
5
44
26
275
0.92
0.08
4.3
3.3
—
—
—
0
0
7
68
1.03
0.08
1.9
1.8
299.6
335.0
nmol/l
—
7
63
27
257
1.07
0.06
2.7
3.0
—
—
—
0
0
48
492
0.95
0.05
4.9
3.7
—
—
—
0
0
10
93
1.08
0.02
3.8
2.8
1.7
1.6
%
—
10
82
66
667
0.96
0.01
13.7
12.5
39.6
40.8
%
1.00
43
482
13
133
0.97
0.00
1.2
1.3
115.2
33.0
iu/ml
—
5
48
16
163
0.98
0.00
5.5
3.2
—
—
—
0
0
22
223
0.98
0.00
3.8
3.1
23.2
42.8
mg/l
0.66
13
135
73
726
1.03
0.00
19.9
11.5
15.3
22.0
mg/l
2.25
64
545
23
234
0.98
0.00
5.4
3.8
1.8
5.6
mg/mmol
1.61
15
143
14
139
1.01
0.00
1.5
1.3
2.1
2.5
g/l
—
8
73
0
5
0.00
0.00
0.0
1.6
—
8.8
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
64
0.93
0.00
1.5
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
19.0
—
0
5
9
99
0.90
0.00
1.6
1.3
—
447.7
—
0
26
5
53
0.94
0.00
7.4
3.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
78
780
1.00
0.00
21.9
12.8
82.9
77.0
umol/l
0.39
78
780
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
62
0.97
0.00
1.3
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
0.00
6.2
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_INTRATHORACIC_NOS_EXALLC – Benign neoplasm: Other specified/unspecified intrathoracic organs (+ respiratory system NOS of Icd-9)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).