Risteys · G6

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G52.1 Hospital discharge: ICD-9 — 3521 Hospital discharge: ICD-8 — 35602 Cause of death: ICD-10 — G52.1 Cause of death: ICD-9 — 3521 Cause of death: ICD-8 — 35602 2 out of 7 registries used, show all original rules.	68
4. Check minimum number of events None	68
5. Include endpoints None	68
6. Filter based on genotype QC (FinnGen only)	67

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	479	287	186
Only index persons	424	266	158
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	54.76	53.17	56.97
Only index persons	53.35	52.25	55.20

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	67	40	27
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	55.17	54.12	56.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
68: Matched controls
680

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G52.1

ICD-10 Finland

Disorders of glossopharyngeal nerve

+∞

85.6

N03AF01

ATC

carbamazepine; oral, rectal

21.5

18.0

G50.0

ICD-10 Finland

Trigeminal neuralgia

129.1

10.7

N03AX16

ATC

[U] pregabalin

5.5

10.6

G50.1

ICD-10 Finland

Atypical facial pain

115.4

9.7

A02BC05

ATC

esomeprazole; systemic

3.9

7.2

173

R07.0

ICD-10 Finland

Pain in throat

9.0

6.8

GD1AA

NOMESCO Finland

Thorax X-ray examination

3.8

6.8

202

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3022145) Colonoscopy Study observation

3.64

4.50

1.3

—

(3045424) Erythrocytes [Presence] in Urine

8.86

2.79

1.0

1.3

—

(3045414) Leukocytes [Presence] in Urine

4.17

2.55

1.8

1.9

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

4.75

2.55

1.0

1.7

0.33

1.73

ug/l

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

4.95

2.32

1.0

1.5

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.95

2.32

1.0

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

272

2.02

2.08

10.8

6.8

1.18

1.20

mmol/l

1.01

227

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

118

2.13

1.99

3.6

1.8

0.97

1.39

mg/l

0.42

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

4.40

1.85

5.4

2.3

165.40

189.67

—

(3031040) Bacteria [#/volume] in Urine by Automated count

369

2.02

1.85

7.1

4.5

—

6532.00

—

(4094501) Cardiovascular stress test using bicycle ergometer

3.55

1.79

1.2

1.1

—

(3019225) pH of Specimen

2.75

1.75

4.5

4.8

—

(3025941) Bacteria identified in Stool by Culture

2.69

1.66

1.8

1.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

212

1.85

1.65

2.4

1.9

81.12

87.97

pmol/l

0.56

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.76

1.64

1.4

2.1

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

3.76

1.64

5.4

1.4

92.60

97.64

—

(40761535) Cells panel - Urine sediment

2.49

1.64

2.6

3.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

215

1.81

1.56

2.6

2.2

79.60

76.30

nmol/l

0.30

187

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

124

1.87

1.41

3.0

2.4

—

(3008898) HLA-B27 [Presence]

3.09

1.38

1.2

1.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.53

1.34

1.4

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.91

1.31

1.0

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.91

1.31

1.4

1.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.38

1.29

31.6

13.0

96.19

94.58

—

(3020891) Body temperature

2.76

1.24

3.8

5.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.25

1.23

1.9

1.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

249

1.63

1.14

8.2

6.0

—

(3023368) Bacteria identified in Blood by Culture

134

1.70

1.08

3.8

4.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.37

1.05

1.8

1.6

—

(3022313) Gas panel - Capillary blood

2.37

1.05

3.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.81

1.04

1.2

1.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

130

1.64

0.94

4.4

3.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.77

0.92

1.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.81

0.92

7.7

8.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.17

0.92

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.17

0.92

2.7

1.5

—

(3019309) Folate [Moles/volume] in Red Blood Cells

114

1.65

0.90

1.5

1.6

910.50

1299.28

nmol/l

—

(36660697) Celiac disease serology panel - Serum

2.09

0.89

1.2

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.75

0.82

3.0

2.4

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.77

0.78

29.1

10.4

111.56

122.56

g/l

—

(3026008) Bacteria identified in Urine by Culture

181

1.50

0.78

4.0

2.9

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.26

0.78

1.0

—

(3012516) Albumin [Mass/volume] in Urine

154

1.53

0.78

3.0

6096.31

42.29

mg/l

0.77

100

(3019060) Gas panel - Arterial blood

1.94

0.76

5.1

4.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.94

0.76

2.9

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

165

1.49

0.73

2.8

2.5

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.99

0.72

1.8

4.1

25.10

24.82

mmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

318

1.44

0.72

7.4

9.1

3.62

4.03

e9/l

0.67

275

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.92

0.70

1.4

1.1

—

(3000991) Gas panel - Venous blood

1.70

0.69

33.9

11.0

—

(40768804) Tissue Pathology biopsy report

234

1.42

0.65

1.9

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

312

1.41

0.65

3.4

2.8

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.78

0.65

3.6

3.4

4.82

5.47

kpa

—

(3013115) Eosinophils [#/volume] in Blood

274

1.40

0.63

6.5

5.7

0.19

0.17

e9/l

0.31

236

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

394

1.42

0.63

4.3

3.7

15.20

14.94

pmol/l

0.27

350

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

116

1.50

0.61

2.1

1.6

442.64

463.30

pmol/l

0.14

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

501

1.51

0.60

5.5

4.3

2.23

1.93

mu/l

0.75

442

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.78

0.59

36.3

9.7

26.20

26.08

mmol/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.63

0.56

1.2

1.5

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

538

1.53

0.53

4.8

4.5

1.54

1.50

mmol/l

0.27

488

(3037467) Urinalysis macro (dipstick) panel - Urine

370

1.35

0.52

7.8

4.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

271

1.34

0.51

22.9

12.9

1.23

1.22

inr

—

(3019150) Specific gravity of Urine by Refractometry

121

1.42

0.50

4.7

3.9

—

1.02

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.54

0.49

1.0

1.4

—

(3042936) Bacteria identified in Isolate by Culture

1.51

0.49

3.3

1.7

—

(3000494) Fungus identified in Specimen by Culture

1.53

0.47

1.5

1.3

—

(3001604) Monocytes [#/volume] in Blood

264

1.32

0.47

6.5

5.6

0.54

0.57

e9/l

0.41

229

(3006315) Basophils [#/volume] in Blood

264

1.32

0.47

6.5

5.6

0.04

e9/l

0.11

228

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

542

1.48

0.46

4.7

4.6

4.67

4.65

mmol/l

0.05

495

(3012095) Magnesium [Moles/volume] in Serum or Plasma

0.61

0.46

3.7

2.8

0.84

0.82

mmol/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

207

1.33

0.46

3.3

2.9

—

(3009508) Creatinine [Moles/volume] in Urine

160

1.35

0.46

2.8

2.9

6.57

6.89

mmol/l

0.08

135

(3015377) Calcium [Moles/volume] in Serum or Plasma

189

1.33

0.44

2.3

2.9

2.33

2.36

mmol/l

0.31

168

(3002256) Pathology report gross observation

1.38

0.42

1.4

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.38

0.42

1.6

1.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.48

0.42

25.9

8.4

105.40

103.01

mmol/l

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.40

0.0

2.6

—

(3019198) Lymphocytes [#/volume] in Blood

269

1.28

0.40

7.1

5.6

1.57

1.98

e9/l

0.79

235

(3049717) Cytology report of Urine Cyto stain

0.00

0.39

0.0

2.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.33

0.38

1.9

1.4

—

(3000492) Spirometry study

1.47

0.37

1.5

1.2

—

(3021589) Normoblasts [#/volume] in Blood

252

1.26

0.36

7.1

9.0

0.00

e9/l

0.71

207

(3002385) Erythrocyte distribution width [Ratio]

475

1.29

0.34

18.2

16.7

17.19

15.11

0.98

467

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

111

1.33

0.33

1.4

1.2

0.67

0.72

u/ml

—

(3002032) Base excess in Venous blood by calculation

1.39

0.32

5.3

4.0

1.86

2.86

mmol/l

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.33

0.31

5.3

3.9

6.20

5.65

kpa

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.28

0.30

1.7

2.6

4.94

7.38

umol/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

139

0.75

0.30

6.1

4.4

18.40

22.72

—

(3044889) 12 lead EKG panel

397

1.23

0.29

4.4

4.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.26

0.28

1.8

1.4

—

(40768797) Stomach Pathology biopsy report

1.25

0.26

1.2

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

167

0.80

0.25

3.6

—

(3018095) Leukocytes [#/volume] in Urine

203

1.20

0.23

4.1

3.5

3.37

96.89

e6/l

1.26

148

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.27

0.23

1.6

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.24

0.22

1.6

2.2

10.01

10.64

g/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.29

0.22

1.9

1.8

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

105.58

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

4.2

—

3.88

—

(3003694) ABO and Rh group [Type] in Blood

143

0.80

0.21

1.9

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

166

1.20

0.21

3.2

3.6

2.42

6.39

mg/mmol

—

105

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.1

—

79.26

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.19

0.20

1.2

1.7

0.20

g/l

—

(1761868) Lipid panel - Serum or Plasma

204

0.84

0.19

2.6

3.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

549

1.24

0.19

5.3

5.2

2.75

2.72

mmol/l

0.09

499

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

560

1.24

0.18

22.2

13.5

24.43

22.73

mg/l

0.13

429

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

0.75

0.18

2.4

4.1

2.84

8.37

ug/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.73

0.18

1.6

1.7

—

(40758558) Short blood count panel - Blood

130

0.82

0.18

4.6

6.9

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.14

0.17

2.7

1.9

15.56

20.98

—

(3002582) Erythrocytes [#/volume] in Urine

181

0.85

0.16

3.3

2.9

4.08

41.99

e6/l

—

136

(3022948) Iron [Moles/volume] in Serum or Plasma

1.24

0.16

2.9

1.8

10.21

13.14

umol/l

—

(40761511) CBC panel - Blood by Automated count

583

1.25

0.15

17.6

12.8

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

583

1.25

0.15

23.8

16.2

75.25

77.45

umol/l

0.37

583

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

114

0.86

0.10

1.5

2.7

2.39

2.45

mmol/l

—

103

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.12

0.08

1.4

1.6

—

(3035941) MCH [Entitic mass]

614

0.94

0.08

30.8

19.9

30.48

30.36

0.19

604

(3026361) Erythrocytes [#/volume] in Blood

614

0.94

0.08

31.1

20.0

4.33

4.46

e12/l

0.72

594

(3000963) Hemoglobin [Mass/volume] in Blood

614

0.94

0.08

31.1

20.1

132.10

134.80

g/l

0.72

604

(3007461) Platelets [#/volume] in Blood

614

0.94

0.08

31.2

20.0

253.92

246.15

e9/l

0.53

597

(3024731) MCV [Entitic volume]

614

0.94

0.08

30.8

19.9

91.52

91.25

0.16

604

(3010813) Leukocytes [#/volume] in Blood

614

0.94

0.08

31.1

20.0

6.98

6.66

e9/l

0.17

593

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.06

0.08

2.9

1.8

2.50

2.32

g/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.04

0.07

3.2

1.7

—

(3026782) Osmolality of Urine

121

0.89

0.06

2.6

2.7

447.60

554.03

mosm/kgh2o

—

100

(36304419) Bacteria [Presence] in Urine

160

1.08

0.04

3.5

2.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

261

1.06

0.03

3.2

2.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

232

1.05

0.02

4.5

3.9

—

(3030467) Casts [#/volume] in Urine by Automated count

167

1.02

0.00

3.3

2.7

0.01

0.36

e6/l

2.57

123

(3013512) EKG study

161

0.99

0.00

4.9

4.4

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

166

1.03

0.00

7.8

4.9

1.26

2.76

ug/l

1.36

145

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.00

0.00

2.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.00

0.00

2.6

3.5

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.8

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.0

—

27.38

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

-0.00

0.0

2.0

—

238.87

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.3

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.6

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.6

—

31.86

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

4.20

—

(3045716) Anion gap in Serum or Plasma

0.00

-0.00

0.0

2.0

—

8.48

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3016038) Potassium [Moles/volume] in Urine

0.00

-0.00

0.0

1.0

—

25.75

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.1

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.5

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

13.30

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

329.40

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

1.11

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

1.38

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.4

—

(3025577) Chromium [Mass/volume] in Blood

0.00

-0.00

0.0

3.0

—

3.50

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

1.0

—

12.84

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

3.0

—

7.00

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

2.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_DISGLO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_DISGLO.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_DISGLO – Disorders of glossopharyngeal nerve

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

NAME	G6_DISGLO
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G521
HD_ICD_9	3521
HD_ICD_8	35602
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G521
COD_ICD_9	3521
COD_ICD_8	35602
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Disorders of glossopharyngeal nerve

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints