Benign neoplasm: Ciliary body

CD2_BENIGN_CILIARY_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data
1. Apply sex-specific rule None	-
2. Check conditions None
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D31.4& Cause of death: ICD-10 — D31.4& 2 out of 7 registries used, show all original rules.	-
4. Check minimum number of events None	-
5. Include endpoints None	-
6. Filter based on genotype QC (FinnGen only) None	-

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D31
Name in latin: Neoplasma benignum corporis ciliaris

NAME	CD2_BENIGN_CILIARY_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D314
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D314
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Ciliary body based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Ciliary body

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	95	51	44
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	63.77	58.91	69.39

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
84: Matched controls
841

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D31.4

ICD-10 Finland

Benign neoplasm: Ciliary body

+∞

120.9

XCD10

NOMESCO Finland

Electrophysiological examination of eye

135.1

44.8

CH2S4

NOMESCO Finland

Photography of iris

+∞

25.3

D31.3

ICD-10 Finland

Benign neoplasm: Choroid

275.6

21.6

XCK10

NOMESCO Finland

Photography of fundus of eye

12.5

18.1

Z01.0

ICD-10 Finland

Examination of eyes and vision

7.7

13.4

CH3S4

NOMESCO Finland

Photography of iridocorneal angle

+∞

11.7

CK2L4

NOMESCO Finland

Wide-field/panoramic imaging of ocular fundus

62.5

9.9

CK2X4

NOMESCO Finland

Optical coherence tomography (OCT) of ocular fundus

5.9

7.1

C69.30

ICD-10 Finland

Malignant tumor of the chorioidea without histology

+∞

6.3

C69.40

ICD-10 Finland

Malignant tumor of ciliary body without histology

+∞

6.3

115

Kela drug reimbursment

Breast cancer

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(42870588) Differential panel, method unspecified - Blood

223

2.93

6.16

5.1

5.4

—

(4035726)

4.48

4.29

1.4

1.3

—

(3002256) Pathology report gross observation

3.43

4.20

1.3

1.1

—

(3030467) Casts [#/volume] in Urine by Automated count

184

2.22

3.15

4.2

2.6

0.4

e6/l

0.05

132

(40768804) Tissue Pathology biopsy report

241

2.14

3.15

2.1

1.6

—

(36304419) Bacteria [Presence] in Urine

179

2.19

3.02

4.1

2.4

—

(3002582) Erythrocytes [#/volume] in Urine

203

2.15

3.02

4.0

2.7

15.6

348.7

e6/l

0.52

153

(3045142) Bone marrow Pathology biopsy report

7.46

2.58

1.0

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

394

1.94

2.53

10.8

6.2

4.0

4.3

e9/l

0.69

343

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

316

1.88

2.36

3.9

4.9

1.2

mmol/l

0.34

280

(3023520) Reticulocytes [#/volume] in Blood

2.56

2.35

1.7

3.1

74.7

68.6

e9/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

337

1.86

2.28

4.7

5.1

25.1

28.0

0.69

307

(3018418) pH of Serum or Plasma

205

1.93

2.27

4.1

3.2

7.4

—

(3021589) Normoblasts [#/volume] in Blood

309

1.79

2.03

10.2

8.2

0.0

e9/l

0.00

255

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.35

1.88

2.1

1.8

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

227

1.78

1.82

3.5

3.4

875.9

1095.9

ng/l

0.40

192

(40761536) Microorganisms panel - Urine sediment

2.35

1.76

4.5

3.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.27

1.75

2.1

1.7

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

349

1.69

1.70

5.0

5.2

1.2

mmol/l

0.29

303

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

115

1.94

1.69

3.7

2.5

1.3

2.4

e6/l

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.94

1.68

1.0

1.4

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.94

1.68

1.0

1.4

—

(3032080) INR in Blood by Coagulation assay

304

1.68

1.67

15.4

8.6

1.3

1.2

inr

0.03

(3020564) Creatinine [Moles/volume] in Serum or Plasma

824

2.75

1.65

19.5

13.9

78.7

79.0

umol/l

0.04

824

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

243

1.70

1.61

3.7

2.8

—

(40768797) Stomach Pathology biopsy report

118

1.88

1.57

1.2

1.1

—

(3018095) Leukocytes [#/volume] in Urine

245

1.68

1.55

4.9

3.3

19.3

76.0

e6/l

1.22

170

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

328

1.64

1.53

2.1

2.2

82.0

77.7

nmol/l

0.40

288

(3001604) Monocytes [#/volume] in Blood

353

1.59

1.39

5.3

5.1

0.6

e9/l

0.25

305

(3009542) Hematocrit [Volume Fraction] of Blood

695

1.81

1.34

20.4

12.4

41.0

40.5

0.32

493

(3006315) Basophils [#/volume] in Blood

356

1.57

1.32

5.3

5.1

0.0

e9/l

0.43

309

(3022145) Colonoscopy Study observation

1.99

1.31

1.0

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.33

1.28

1.9

1.6

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.49

1.26

1.0

1.4

—

(3013115) Eosinophils [#/volume] in Blood

369

1.54

1.25

6.7

5.1

0.2

e9/l

0.18

323

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

734

1.86

1.24

18.8

11.0

76.5

78.3

ml/min/173m2

0.36

587

(40761511) CBC panel - Blood by Automated count

812

2.14

1.22

14.5

11.3

—

(3025941) Bacteria identified in Stool by Culture

2.20

1.22

1.0

1.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

439

1.53

1.21

3.0

2.8

—

(3044889) 12 lead EKG panel

562

1.57

1.19

4.5

3.8

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

772

1.96

1.19

16.6

11.5

21.4

21.0

mg/l

0.03

578

(3019198) Lymphocytes [#/volume] in Blood

364

1.51

1.16

5.3

5.1

2.6

1.9

e9/l

0.33

322

(3015377) Calcium [Moles/volume] in Serum or Plasma

235

1.55

1.13

3.0

2.0

2.3

2.4

mmol/l

0.47

200

(40758558) Short blood count panel - Blood

156

1.63

1.12

10.8

5.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.04

1.12

1.1

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

148

1.63

1.11

5.5

4.3

—

(1761868) Lipid panel - Serum or Plasma

291

1.51

1.10

3.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

2.14

1.05

1.4

2.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.75

1.04

2.1

1.7

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

806

1.94

1.04

19.5

14.2

140.0

139.7

mmol/l

0.37

787

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.08

1.02

1.0

1.5

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

268

1.48

1.00

4.1

3.9

1.4

2.0

ug/l

1.33

236

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.99

0.0

1.3

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.99

0.0

1.4

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

306

1.47

0.99

3.1

2.7

119.8

127.5

ug/l

0.09

283

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.82

0.98

2.9

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

574

1.49

0.97

4.6

4.2

15.0

14.8

pmol/l

0.28

514

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

119

1.63

0.97

4.0

2.4

1.0

1.1

e6/l

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

2.30

0.95

1.3

1.2

—

0.2

—

(1002224) Polysomnography panel

2.14

0.91

1.0

1.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.14

0.91

1.0

1.2

—

(3013707) Erythrocyte sedimentation rate by Westergren method

570

1.44

0.87

4.3

4.2

8.3

10.8

mm/h

0.91

517

(3004588) Protein electrophoresis panel - Serum or Plasma

1.85

0.87

1.6

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.78

0.86

1.2

1.6

—

(3023368) Bacteria identified in Blood by Culture

175

1.50

0.86

5.5

3.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

710

1.55

0.85

5.3

4.9

1.8

3.6

mu/l

0.54

644

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.80

0.0

1.3

—

3.5

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.78

0.0

1.3

—

3.1

—

(3000492) Spirometry study

1.64

0.73

1.2

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

326

0.72

0.68

3.8

3.9

14.5

42.5

ng/l

2.00

223

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

777

1.54

0.65

4.9

4.8

1.4

1.5

mmol/l

0.35

712

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

213

1.37

0.64

1.5

1.7

1.0

1.4

mmol/l

3.10

184

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

111

0.60

0.63

1.4

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.59

0.0

5.2

—

28.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

805

1.53

0.56

5.3

2.7

mmol/l

0.08

742

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.57

0.54

4.3

4.5

25.2

25.3

mmol/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

164

1.36

0.52

1.6

1.7

1.0

mg/l

0.43

131

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

785

1.45

0.52

4.9

4.8

4.6

4.7

mmol/l

0.40

726

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.56

0.49

2.4

4.1

4.3

4.7

pmol/l

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.56

0.49

2.1

1.5

—

(3019309) Folate [Moles/volume] in Red Blood Cells

150

1.33

0.44

2.8

1.7

1133.9

1213.2

nmol/l

0.11

111

(3008898) HLA-B27 [Presence]

1.65

0.44

1.0

1.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

758

1.35

0.43

4.3

1.1

1.3

mmol/l

1.90

687

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.54

0.42

1.8

1.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

510

1.24

0.42

3.9

3.6

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

0.00

0.41

0.0

2.0

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

124.0

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.41

0.0

1.0

—

(3009261) Glucose [Presence] in Urine by Test strip

362

1.23

0.41

2.9

3.3

0.0

estimate

0.00

(3031040) Bacteria [#/volume] in Urine by Automated count

471

1.23

0.40

4.7

3.8

—

727.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.45

0.40

1.0

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.39

0.0

1.2

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.39

0.0

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

355

1.22

0.37

3.0

3.3

0.0

estimate

0.00

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

150

1.25

0.29

2.4

2.6

0.8

ug/l

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

758

1.25

0.29

5.9

6.4

38.9

40.5

mmol/mol

1.41

706

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

283

0.84

0.26

3.3

3.4

—

(3000494) Fungus identified in Specimen by Culture

0.71

0.25

1.7

1.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.71

0.25

1.2

1.5

—

(3012516) Albumin [Mass/volume] in Urine

261

0.84

0.24

2.7

3.2

22.6

330.8

mg/l

0.57

148

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

773

1.22

0.23

5.0

4.9

5.9

6.0

mmol/l

0.51

701

(3021601) Nitrite [Presence] in Urine by Test strip

358

1.15

0.23

4.1

4.5

0.0

estimate

0.00

(3042936) Bacteria identified in Isolate by Culture

102

0.76

0.22

1.5

—

(3000330) Specific gravity of Urine by Test strip

1.23

0.22

2.0

2.6

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.4

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.21

0.0

1.0

—

36.0

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.4

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

503.3

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.4

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.0

—

271.5

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

66.6

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

0.00

0.21

0.0

2.0

—

32.5

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.21

0.0

4.4

—

1.4

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.21

0.0

4.4

—

7.3

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

1.4

—

2.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.21

0.0

1.8

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.21

0.20

1.7

1.2

—

(3022621) pH of Urine by Test strip

1.21

0.20

2.3

1.9

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

214

1.16

0.20

3.0

3.6

29.5

24.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

276

0.87

0.18

3.5

4.0

3.2

7.1

mg/mmol

0.84

155

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.14

0.18

1.7

1.4

—

(3012544) pH of Venous blood

0.74

0.17

3.8

4.0

—

(3019225) pH of Specimen

1.14

0.16

1.5

3.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

210

1.13

0.13

3.5

2.7

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

230

1.12

0.13

2.4

2.0

75.5

59.0

u/l

0.42

207

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.17

0.10

1.4

1.7

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.09

0.10

4.4

2.0

10.7

10.8

g/l

—

(36660697) Celiac disease serology panel - Serum

0.82

0.08

1.0

1.1

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.87

0.07

1.1

1.7

1.1

1.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.06

0.07

1.1

1.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.86

0.07

4.6

7.0

—

(3044640) Blood type and Crossmatch panel - Blood

217

1.08

0.06

2.1

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

140

1.08

0.05

1.1

1.3

2.5

2.8

g/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

160

1.08

0.04

1.9

3.6

—

(3029937) Albumin [Presence] in Urine by Test strip

180

1.07

0.04

3.3

3.9

0.0

estimate

0.00

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

330

1.05

0.03

2.3

1.9

86.7

99.5

pmol/l

0.78

167

(3037522) Nuclear Ab [Titer] in Serum

1.10

0.03

1.1

1.4

—

595.6

—

(3026008) Bacteria identified in Urine by Culture

202

1.05

0.02

3.1

2.6

—

(3015736) pH of Urine

283

1.04

0.01

2.3

3.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

329

1.00

0.00

2.9

3.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

163

0.98

0.00

2.0

1.9

—

(3013512) EKG study

237

1.02

0.00

4.1

4.0

—

(3003694) ABO and Rh group [Type] in Blood

185

1.03

0.00

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

105

1.05

0.00

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.01

0.00

1.2

1.7

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.0

1.1

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(4024509)

0.00

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.6

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

6.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.0

3.2

—

76.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.6

—

106.9

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.98

0.00

2.0

1.6

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.2

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

10.3

—

(3006576) Bicarbonate [Moles/volume] in Blood

0.00

0.0

6.0

—

26.1

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

2.6

—

7.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

2.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

3.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.6

—

4.0

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.0

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(4027681)

0.00

0.0

1.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(4268621)

0.00

0.0

1.5

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.90

0.00

1.2

1.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.1

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.7

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.2

—

235.5

—

(4146454)

0.00

0.0

2.8

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.5

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.1

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.94

0.00

2.0

1.7

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.4

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

0.0

6.2

—

0.6

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_CILIARY_EXALLC – Benign neoplasm: Ciliary body

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Ciliary body

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints