Lichenoid drug reaction

LICHENOID_DRUG_REACTION

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L43.2# 1 out of 7 registries used, show all original rules.	94
4. Check minimum number of events None	94
5. Include endpoints None	94
6. Filter based on genotype QC (FinnGen only)	94

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF5

NAME	LICHENOID_DRUG_REACTION
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L432
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Lichenoid drug reaction based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	477	331	146
Only index persons	447	310	137
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	60.35	59.94
Only index persons	59.71	59.82	59.48

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	94	66	28
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	58.16	57.86	58.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
85: Matched controls
847

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L43.2

ICD-10 Finland

Lichenoid drug reaction

+∞

122.3

L43.8

ICD-10 Finland

Other lichen planus

43.3

20.7

L43.9

ICD-10 Finland

Lichen planus, unspecified

26.6

14.1

EKA10

NOMESCO Finland

Biopsy of cheek

16.0

10.7

K13.74

ICD-10 Finland

Lichen rubs planus in the mouth

37.2

8.3

A07AA02

ATC

nystatin; oral

7.3

8.0

L43.0

ICD-10 Finland

Hypertrophic lichen planus

20.7

7.8

D07AD01

ATC

clobetasol; topical

4.1

7.0

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

5.6

6.9

XQ802

NOMESCO Finland

Epicutan test

10.5

6.5

ECA20

NOMESCO Finland

Biopsy of gingiva

19.8

6.4

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

114

3.92

8.51

5.7

5.1

28.5

33.4

1.26

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

106

3.69

7.38

7.5

8.1

—

(3019225) pH of Specimen

3.85

7.14

8.0

3.2

—

(3026389) Candida sp identified in Specimen by Organism specific culture

13.79

6.24

2.1

1.3

—

(1761868) Lipid panel - Serum or Plasma

272

0.26

4.78

2.7

3.4

—

(3002385) Erythrocyte distribution width [Ratio]

661

0.42

4.06

18.9

19.2

13.7

13.9

0.67

647

(4146454)

8.29

3.62

3.6

3.0

—

(3013512) EKG study

273

2.24

3.59

4.6

4.2

—

(3037522) Nuclear Ab [Titer] in Serum

108

2.50

3.24

1.4

288.0

638.7

titre

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

10.45

3.01

1.0

1.2

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

297

2.07

3.00

3.8

3.5

1806.5

1293.9

ng/l

0.34

254

(3012516) Albumin [Mass/volume] in Urine

273

2.06

2.91

3.0

116.1

59.2

mg/l

0.25

169

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

198

2.12

2.89

1.9

2.1

—

(4010399)

2.78

2.87

1.4

1.5

—

(3009508) Creatinine [Moles/volume] in Urine

272

1.98

2.64

3.0

2.9

6.8

7.0

mmol/l

0.11

216

(3044640) Blood type and Crossmatch panel - Blood

264

1.98

2.61

1.9

2.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

293

1.94

2.52

3.6

3.8

19.2

9.5

mg/mmol

0.24

176

(42870588) Differential panel, method unspecified - Blood

259

1.95

2.48

6.3

5.2

—

(3044889) 12 lead EKG panel

606

0.53

2.38

4.1

4.2

—

(3044927) Protein electrophoresis panel - Urine

5.79

2.24

1.4

1.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

367

1.85

2.23

2.9

2.3

80.6

78.0

nmol/l

0.27

314

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

384

1.79

2.03

3.1

3.8

—

(40761535) Cells panel - Urine sediment

2.26

1.93

3.3

3.2

—

(3013707) Erythrocyte sedimentation rate by Westergren method

626

1.98

1.90

6.6

4.5

15.5

13.6

mm/h

0.51

559

(3037467) Urinalysis macro (dipstick) panel - Urine

574

1.86

1.84

6.8

4.5

—

(3017732) Neutrophils [#/volume] in Blood

2.46

1.78

1.9

3.0

3.6

e9/l

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

665

2.02

1.78

8.5

7.5

77.3

79.4

u/l

0.21

612

(3000330) Specific gravity of Urine by Test strip

0.00

1.76

0.0

4.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

189

1.77

1.67

6.9

3.7

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

409

1.68

1.65

9.4

5.2

1.2

mmol/l

0.41

369

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.82

1.61

1.1

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.55

1.58

1.5

1.9

—

(3026493) Urate [Moles/volume] in Serum or Plasma

201

1.72

1.56

2.3

3.2

356.2

12835.5

umol/l

1.82

157

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

3.46

1.54

1.0

1.3

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.84

1.46

1.7

1.3

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.52

1.42

1.6

1.8

—

(3029937) Albumin [Presence] in Urine by Test strip

234

1.63

1.38

7.0

4.3

0.0

estimate

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.05

1.37

1.2

—

(3000494) Fungus identified in Specimen by Culture

108

1.82

1.34

1.2

1.5

—

(3022313) Gas panel - Capillary blood

2.33

1.28

5.4

2.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

458

1.55

1.24

10.6

5.7

1.2

mmol/l

0.44

379

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

352

1.53

1.21

3.6

4.3

18.0

36.2

ng/l

1.21

272

(3009261) Glucose [Presence] in Urine by Test strip

422

1.52

1.17

5.8

4.2

0.0

estimate

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.94

1.15

1.2

2.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

164

1.62

1.14

1.3

1.2

2.0

u/ml

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

769

1.87

1.05

14.0

15.1

70.1

75.0

ml/min/173m2

1.29

637

(40768797) Stomach Pathology biopsy report

125

1.65

1.04

1.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

391

1.47

1.01

4.2

3.8

35.2

g/l

0.01

361

(36660697) Celiac disease serology panel - Serum

1.84

0.98

1.2

—

(3009343) pH of Capillary blood

1.81

0.95

5.2

2.8

—

7.4

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.81

0.95

5.2

2.8

4.8

5.2

kpa

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

2.22

0.93

3.8

1.8

—

(3019060) Gas panel - Arterial blood

1.88

0.92

5.2

3.8

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

282

1.45

0.91

2.1

2.3

55.0

56.1

u/l

0.10

257

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

792

1.76

0.88

5.9

5.0

1.5

mmol/l

0.09

714

(3015377) Calcium [Moles/volume] in Serum or Plasma

312

1.43

0.88

2.6

3.1

2.4

mmol/l

1.39

264

(3015736) pH of Urine

332

1.42

0.86

6.0

3.8

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.81

0.83

2.8

3.0

10.9

9.7

g/l

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

471

1.40

0.83

4.7

5.9

11.2

10.6

umol/l

0.23

444

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

769

1.68

0.82

5.1

4.4

1.2

1.3

mmol/l

0.38

691

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.87

0.80

3.8

2.2

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.79

0.0

5.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

797

1.69

0.77

5.6

5.0

4.6

mmol/l

0.18

728

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

631

1.43

0.74

5.2

4.1

15.0

pmol/l

0.06

568

(3035350) Ketones [Presence] in Urine by Test strip

417

1.37

0.74

5.8

4.1

0.0

estimate

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

2.05

0.74

1.4

1.3

—

0.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

418

1.36

0.72

7.1

5.5

0.0

estimate

—

(40768443) Skin Pathology biopsy report

1.76

0.71

1.6

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.76

0.71

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.90

0.69

1.4

2.0

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

282

0.71

0.65

2.5

3.0

44.5

31.5

u/l

0.43

266

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

504

1.33

0.63

3.7

3.1

57.2

52.0

u/l

0.14

468

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

356

1.32

0.63

1.8

2.0

98.5

98.8

pmol/l

0.01

165

(1002224) Polysomnography panel

0.00

0.60

0.0

1.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

817

1.62

0.59

6.1

5.7

2.6

2.7

mmol/l

0.13

737

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

197

1.37

0.59

1.4

1.9

830000315.2

455.9

pmol/l

0.78

159

(3019309) Folate [Moles/volume] in Red Blood Cells

180

1.37

0.57

2.0

1.7

1166.9

1230.0

nmol/l

0.10

131

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

809

1.53

0.57

17.7

15.1

20.0

23.9

mg/l

0.48

641

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

144

1.40

0.56

1.9

1.8

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

144

1.40

0.56

1.3

1.4

68.7

41.3

iu/ml

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

208

1.35

0.56

2.5

2.1

2.7

3.5

mg/l

1.78

179

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

795

1.53

0.56

6.3

5.2

6.1

mmol/l

0.13

722

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.47

0.54

1.9

1.3

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.53

0.53

2.3

2.1

0.2

g/l

0.22

(40761511) CBC panel - Blood by Automated count

831

1.63

0.52

17.8

14.3

—

(3000492) Spirometry study

1.55

0.52

1.9

1.6

—

(40768804) Tissue Pathology biopsy report

354

1.28

0.51

2.3

2.2

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

111

1.42

0.50

2.8

4.4

7.4

13.2

ug/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.53

0.49

1.8

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

329

1.26

0.46

6.6

4.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.48

0.44

1.8

1.5

—

(3020891) Body temperature

1.59

0.43

4.2

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

2.1

—

39.6

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.41

0.0

1.1

—

(3000991) Gas panel - Venous blood

1.46

0.41

10.7

6.0

—

(3049717) Cytology report of Urine Cyto stain

1.50

0.41

2.8

3.3

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.39

0.0

1.9

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.39

0.0

3.1

—

53.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

698

1.28

0.39

15.9

16.3

39.2

39.1

0.01

456

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.49

0.37

1.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

127

1.31

0.36

2.1

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.46

0.36

3.2

2.6

0.9

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.36

0.34

1.7

1.2

—

(3021960) Folate [Moles/volume] in Serum or Plasma

217

0.79

0.34

1.4

1.5

23.3

23.0

nmol/l

0.02

173

(3007164) IgA [Mass/volume] in Serum or Plasma

147

1.28

0.34

1.6

1.5

2.3

2.4

g/l

0.14

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

788

1.32

0.32

7.5

6.5

40.7

40.8

mmol/mol

0.02

730

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

139

1.27

0.32

1.3

1.4

1.3

17.2

u/ml

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

108

0.72

0.31

1.5

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.23

0.27

1.3

1.4

—

(3042936) Bacteria identified in Isolate by Culture

124

1.25

0.26

1.5

1.8

—

(3002256) Pathology report gross observation

1.26

0.22

1.3

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.21

0.0

3.4

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3004775) Volume in Urine collected for unspecified duration

0.00

0.21

0.0

2.6

—

733.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.3

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

2.6

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.20

0.0

2.4

—

107.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.20

0.0

2.4

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.20

0.0

1.8

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.20

0.0

2.4

—

4.0

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.19

0.20

2.0

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.18

0.18

2.0

1.5

—

(3012544) pH of Venous blood

1.25

0.18

3.6

3.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

193

0.85

0.17

6.2

5.1

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

335

0.89

0.16

3.9

2.6

104.7

103.8

ug/l

0.02

303

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

395

1.11

0.16

3.1

2.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

307

1.12

0.15

4.3

3.3

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

760

1.15

0.15

6.4

5.0

2.1

2.0

mu/l

0.13

678

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.82

0.14

5.0

3.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

137

0.86

0.13

3.2

1.7

3.7

e6/l

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.07

0.09

2.6

3.4

0.8

0.1

e6/l

—

(3018095) Leukocytes [#/volume] in Urine

316

0.93

0.08

4.7

4.0

63.1

58.7

e6/l

0.04

221

(40761536) Microorganisms panel - Urine sediment

0.82

0.08

4.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

234

0.92

0.07

3.9

4.0

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.04

0.07

12.8

5.7

123.4

116.8

g/l

—

(3026782) Osmolality of Urine

168

1.09

0.06

3.1

505.2

517.1

mosm/kgh2o

0.10

143

(3007853) Bacteria identified in Skin by Aerobe culture

1.12

0.06

1.8

1.4

—

(4035726)

1.12

0.06

1.3

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

151

0.91

0.05

3.8

5.3

23.6

21.3

—

(3023368) Bacteria identified in Blood by Culture

229

1.06

0.05

2.7

3.9

—

(3003694) ABO and Rh group [Type] in Blood

190

0.93

0.04

1.2

1.3

—

(3032080) INR in Blood by Coagulation assay

379

1.05

0.04

7.3

8.5

1.1

1.3

inr

—

114

(40758558) Short blood count panel - Blood

201

1.06

0.03

6.3

7.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

102

1.09

0.03

1.9

1.6

—

(3022145) Colonoscopy Study observation

108

0.92

0.03

1.0

1.2

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

152

1.06

0.02

3.6

2.9

0.8

1.0

e6/l

—

(36304419) Bacteria [Presence] in Urine

243

1.04

0.01

4.3

3.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

104

1.07

0.01

2.0

1.7

—

(3026008) Bacteria identified in Urine by Culture

297

1.01

0.00

3.0

3.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.4

—

(3005532) Lymphocytes/100 leukocytes in Pleural fluid

0.00

0.0

1.2

—

68.0

—

(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood

0.00

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3035880) pH of Pleural fluid

0.00

0.0

1.4

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

0.0

6.0

—

53.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.02

0.00

13.8

5.9

1.1

1.5

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

0.0

1.3

—

37.8

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

99.8

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

1.7

—

7.4

—

(4027681)

0.00

0.0

1.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.2

—

9.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.7

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3000919) Neutrophils/100 leukocytes in Pleural fluid

0.00

0.0

1.2

—

18.3

—

(4024509)

0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

3.8

—

(3020876) Protein [Mass/time] in 24 hour Urine

0.00

0.0

2.7

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.3

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(4062490)

0.00

0.0

1.5

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

13.0

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.4

—

(3004451) EKG impression Narrative

0.00

0.0

1.6

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3000012) Reticulocyte production index

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.6

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

2.2

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

861

1.14

0.00

14.0

11.3

24.4

23.6

u/l

0.24

825

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(3001893) Eosinophils/100 leukocytes in Pleural fluid

0.00

0.0

1.2

—

1.1

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

2.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.2

—

(37021550) Renin [Units/volume] in Plasma --upright

0.00

0.0

2.0

—

202.9

—

(3024263) Appearance of Synovial fluid

0.00

0.0

1.1

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint LICHENOID_DRUG_REACTION and mortality.

Females

Parameter	HR [95% CI]	p-value
LICHENOID_DRUG_REACTION	1.212 [0.91, 1.62]	0.194
Birth year	0.994 [0.99, 1.0]	0.168

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 311 females with LICHENOID_DRUG_REACTION died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have LICHENOID_DRUG_REACTION.

N-year risk	Females	Males
1	0.102%	No data
5	0.546%	No data
10	1.518%	No data
15	3.23%	No data
20	5.826%	No data

Relationships between endpoints

↥

Index endpoint: LICHENOID_DRUG_REACTION – Lichenoid drug reaction

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Lichenoid drug reaction

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints