Lichenoid drug reaction

LICHENOID_DRUG_REACTION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L43.2#

1 out of 7 registries used, show all original rules.

94

4. Check minimum number of events

None

94

5. Include endpoints

None

94

6. Filter based on genotype QC (FinnGen only)

94

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 477 331 146
Only index persons 447 310 137
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 60.35 59.94
Only index persons 59.71 59.82 59.48

-FinnGen-

Key figures

All Female Male
Number of individuals 94 66 28
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 58.16 57.86 58.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
85
Matched controls
847
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L43.2
ICD-10 Finland
Lichenoid drug reaction
+∞
122.3
85
*
L43.8
ICD-10 Finland
Other lichen planus
43.3
20.7
25
8
L43.9
ICD-10 Finland
Lichen planus, unspecified
26.6
14.1
19
9
EKA10
NOMESCO Finland
Biopsy of cheek
16.0
10.7
17
13
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
37.2
8.3
10
*
A07AA02
ATC
nystatin; oral
7.3
8.0
19
32
L43.0
ICD-10 Finland
Hypertrophic lichen planus
20.7
7.8
11
6
D07AD01
ATC
clobetasol; topical
4.1
7.0
30
99
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.6
6.9
20
44
XQ802
NOMESCO Finland
Epicutan test
10.5
6.5
12
13
ECA20
NOMESCO Finland
Biopsy of gingiva
19.8
6.4
9
5

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
33
114
3.92
8.51
5.7
5.1
%
28.5
33.4
1.26
15
68
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
30
106
3.69
7.38
7.5
8.1
—
—
—
0
0
(3019225) pH of Specimen
26
85
3.85
7.14
8.0
3.2
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
10
8
13.79
6.24
2.1
1.3
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
9
272
0.26
4.78
2.7
3.4
—
—
—
0
0
(3002385) Erythrocyte distribution width [Ratio]
47
661
0.42
4.06
18.9
19.2
%
13.7
13.9
0.67
47
647
(4146454)
7
9
8.29
3.62
3.6
3.0
—
—
—
0
0
(3013512) EKG study
45
273
2.24
3.59
4.6
4.2
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
23
108
2.50
3.24
1.4
1.4
titre
288.0
638.7
—
5
31
(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay
5
5
10.45
3.01
1.0
1.2
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
46
297
2.07
3.00
3.8
3.5
ng/l
1806.5
1293.9
0.34
30
254
(3012516) Albumin [Mass/volume] in Urine
43
273
2.06
2.91
3.0
3.0
mg/l
116.1
59.2
0.25
20
169
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
34
198
2.12
2.89
1.9
2.1
—
—
—
0
0
(4010399)
15
60
2.78
2.87
1.4
1.5
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
42
272
1.98
2.64
3.0
2.9
mmol/l
6.8
7.0
0.11
27
216
(3044640) Blood type and Crossmatch panel - Blood
41
264
1.98
2.61
1.9
2.2
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
44
293
1.94
2.52
3.6
3.8
mg/mmol
19.2
9.5
0.24
20
176
(42870588) Differential panel, method unspecified - Blood
40
259
1.95
2.48
6.3
5.2
—
—
—
0
0
(3044889) 12 lead EKG panel
46
606
0.53
2.38
4.1
4.2
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
5
9
5.79
2.24
1.4
1.1
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
51
367
1.85
2.23
2.9
2.3
nmol/l
80.6
78.0
0.27
40
314
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
52
384
1.79
2.03
3.1
3.8
—
—
—
0
0
(40761535) Cells panel - Urine sediment
15
73
2.26
1.93
3.3
3.2
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
75
626
1.98
1.90
6.6
4.5
mm/h
15.5
13.6
0.51
64
559
(3037467) Urinalysis macro (dipstick) panel - Urine
70
574
1.86
1.84
6.8
4.5
—
—
—
0
0
(3017732) Neutrophils [#/volume] in Blood
11
48
2.46
1.78
1.9
3.0
e9/l
3.0
3.6
—
6
33
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
78
665
2.02
1.78
8.5
7.5
u/l
77.3
79.4
0.21
64
612
(3000330) Specific gravity of Urine by Test strip
0
46
0.00
1.76
0.0
4.4
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
29
189
1.77
1.67
6.9
3.7
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
53
409
1.68
1.65
9.4
5.2
mmol/l
1.2
1.2
0.41
41
369
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
26
2.82
1.61
1.1
1.1
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
33
2.55
1.58
1.5
1.9
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
30
201
1.72
1.56
2.3
3.2
umol/l
356.2
12835.5
1.82
24
157
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
5
15
3.46
1.54
1.0
1.3
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
6
22
2.84
1.46
1.7
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
29
2.52
1.42
1.6
1.8
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
33
234
1.63
1.38
7.0
4.3
estimate
0.0
0.0
—
7
78
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
17
3.05
1.37
1.2
1.2
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
18
108
1.82
1.34
1.2
1.5
—
—
—
0
0
(3022313) Gas panel - Capillary blood
8
36
2.33
1.28
5.4
2.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
56
458
1.55
1.24
10.6
5.7
mmol/l
1.2
1.2
0.44
39
379
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
45
352
1.53
1.21
3.6
4.3
ng/l
18.0
36.2
1.21
37
272
(3009261) Glucose [Presence] in Urine by Test strip
52
422
1.52
1.17
5.8
4.2
estimate
0.0
0.0
—
8
77
(3004588) Protein electrophoresis panel - Serum or Plasma
12
66
1.94
1.15
1.2
2.2
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
24
164
1.62
1.14
1.3
1.2
u/ml
1.2
2.0
—
9
46
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
84
769
1.87
1.05
14.0
15.1
ml/min/173m2
70.1
75.0
1.29
62
637
(40768797) Stomach Pathology biopsy report
19
125
1.65
1.04
1.3
1.3
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
48
391
1.47
1.01
4.2
3.8
g/l
35.2
35.2
0.01
38
361
(36660697) Celiac disease serology panel - Serum
9
51
1.84
0.98
1.2
1.2
—
—
—
0
0
(3009343) pH of Capillary blood
9
52
1.81
0.95
5.2
2.8
—
7.4
—
0
7
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
9
52
1.81
0.95
5.2
2.8
kpa
4.8
5.2
—
9
46
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
6
28
2.22
0.93
3.8
1.8
—
—
—
0
0
(3019060) Gas panel - Arterial blood
10
56
1.88
0.92
5.2
3.8
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
36
282
1.45
0.91
2.1
2.3
u/l
55.0
56.1
0.10
28
257
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
85
792
1.76
0.88
5.9
5.0
mmol/l
1.5
1.5
0.09
69
714
(3015377) Calcium [Moles/volume] in Serum or Plasma
39
312
1.43
0.88
2.6
3.1
mmol/l
2.4
2.4
1.39
29
264
(3015736) pH of Urine
41
332
1.42
0.86
6.0
3.8
—
—
—
0
0
(3005719) IgG [Mass/volume] in Serum or Plasma
10
58
1.81
0.83
2.8
3.0
g/l
10.9
9.7
—
10
50
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
55
471
1.40
0.83
4.7
5.9
umol/l
11.2
10.6
0.23
46
444
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
83
769
1.68
0.82
5.1
4.4
mmol/l
1.2
1.3
0.38
66
691
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
33
1.87
0.80
3.8
2.2
—
—
—
0
0
(1761482) Bacteria [#/volume] in Urine by Culture
0
27
0.00
0.79
0.0
5.7
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
85
797
1.69
0.77
5.6
5.0
mmol/l
4.6
4.6
0.18
68
728
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
70
631
1.43
0.74
5.2
4.1
pmol/l
15.0
15.0
0.06
60
568
(3035350) Ketones [Presence] in Urine by Test strip
49
417
1.37
0.74
5.8
4.1
estimate
0.0
0.0
—
8
84
(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood
5
25
2.05
0.74
1.4
1.3
—
0.0
—
0
5
(3021601) Nitrite [Presence] in Urine by Test strip
49
418
1.36
0.72
7.1
5.5
estimate
0.0
0.0
—
8
82
(40768443) Skin Pathology biopsy report
7
41
1.76
0.71
1.6
1.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
41
1.76
0.71
1.3
1.3
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
5
27
1.90
0.69
1.4
2.0
—
—
—
0
0
(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
22
282
0.71
0.65
2.5
3.0
u/l
44.5
31.5
0.43
22
266
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
57
504
1.33
0.63
3.7
3.1
u/l
57.2
52.0
0.14
44
468
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
42
356
1.32
0.63
1.8
2.0
pmol/l
98.5
98.8
0.01
17
165
(1002224) Polysomnography panel
0
22
0.00
0.60
0.0
1.2
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
86
817
1.62
0.59
6.1
5.7
mmol/l
2.6
2.7
0.13
69
737
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
25
197
1.37
0.59
1.4
1.9
pmol/l
830000315.2
455.9
0.78
20
159
(3019309) Folate [Moles/volume] in Red Blood Cells
23
180
1.37
0.57
2.0
1.7
nmol/l
1166.9
1230.0
0.10
16
131
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
85
809
1.53
0.57
17.7
15.1
mg/l
20.0
23.9
0.48
67
641
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
19
144
1.40
0.56
1.9
1.8
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
19
144
1.40
0.56
1.3
1.4
iu/ml
68.7
41.3
—
6
58
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
26
208
1.35
0.56
2.5
2.1
mg/l
2.7
3.5
1.78
18
179
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
84
795
1.53
0.56
6.3
5.2
mmol/l
6.1
6.1
0.13
68
722
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
9
63
1.47
0.54
1.9
1.3
—
—
—
0
0
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
11
75
1.53
0.53
2.3
2.1
g/l
0.2
0.2
0.22
11
70
(40761511) CBC panel - Blood by Automated count
87
831
1.63
0.52
17.8
14.3
—
—
—
0
0
(3000492) Spirometry study
10
67
1.55
0.52
1.9
1.6
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
41
354
1.28
0.51
2.3
2.2
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
15
111
1.42
0.50
2.8
4.4
ug/l
7.4
13.2
—
10
91
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
10
68
1.53
0.49
1.8
1.5
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
38
329
1.26
0.46
6.6
4.3
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
10
70
1.48
0.44
1.8
1.5
—
—
—
0
0
(3020891) Body temperature
5
32
1.59
0.43
4.2
4.2
—
—
—
0
0
(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma
0
15
0.00
0.41
0.0
2.1
—
39.6
—
0
15
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
10
71
1.46
0.41
10.7
6.0
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
34
1.50
0.41
2.8
3.3
—
—
—
0
0
(3014051) Protein [Presence] in Urine by Test strip
0
19
0.00
0.39
0.0
1.9
—
—
—
0
0
(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma
0
19
0.00
0.39
0.0
3.1
—
53.0
—
0
19
(3009542) Hematocrit [Volume Fraction] of Blood
74
698
1.28
0.39
15.9
16.3
%
39.2
39.1
0.01
33
456
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
6
41
1.49
0.37
1.0
1.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
16
127
1.31
0.36
2.1
1.3
—
—
—
0
0
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
42
1.46
0.36
3.2
2.6
%
0.9
0.9
—
6
42
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
6
45
1.36
0.34
1.7
1.2
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
18
217
0.79
0.34
1.4
1.5
nmol/l
23.3
23.0
0.02
11
173
(3007164) IgA [Mass/volume] in Serum or Plasma
18
147
1.28
0.34
1.6
1.5
g/l
2.3
2.4
0.14
11
82
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
82
788
1.32
0.32
7.5
6.5
mmol/mol
40.7
40.8
0.02
65
730
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
17
139
1.27
0.32
1.3
1.4
u/ml
1.3
17.2
—
8
50
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
8
108
0.72
0.31
1.5
1.4
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
8
66
1.23
0.27
1.3
1.4
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
15
124
1.25
0.26
1.5
1.8
—
—
—
0
0
(3002256) Pathology report gross observation
12
98
1.26
0.22
1.3
1.3
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
11
0.00
0.21
0.0
3.4
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3004775) Volume in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
2.6
—
733.4
—
0
5
(40768800) Prostate Pathology biopsy report
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
(3035285) Chloride [Moles/volume] in Venous blood
0
14
0.00
0.20
0.0
2.4
—
107.5
—
0
14
(3033705) Calcium.ionized [Moles/volume] in Venous blood
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
(3041354) Potassium [Moles/volume] in Venous blood
0
14
0.00
0.20
0.0
2.4
—
4.0
—
0
14
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
6
51
1.19
0.20
2.0
1.3
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
7
60
1.18
0.18
2.0
1.5
—
—
—
0
0
(3012544) pH of Venous blood
10
82
1.25
0.18
3.6
3.3
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
17
193
0.85
0.17
6.2
5.1
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
31
335
0.89
0.16
3.9
2.6
ug/l
104.7
103.8
0.02
25
303
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
42
395
1.11
0.16
3.1
2.6
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
33
307
1.12
0.15
4.3
3.3
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
78
760
1.15
0.15
6.4
5.0
mu/l
2.1
2.0
0.13
62
678
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
8
96
0.82
0.14
5.0
3.4
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
12
137
0.86
0.13
3.2
3.2
e6/l
1.7
3.7
—
6
73
(3030981) Hyaline casts [#/volume] in Urine by Automated count
5
47
1.07
0.09
2.6
3.4
e6/l
0.8
0.1
—
5
47
(3018095) Leukocytes [#/volume] in Urine
30
316
0.93
0.08
4.7
4.0
e6/l
63.1
58.7
0.04
25
221
(40761536) Microorganisms panel - Urine sediment
6
72
0.82
0.08
4.2
4.2
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
22
234
0.92
0.07
3.9
4.0
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
9
87
1.04
0.07
12.8
5.7
g/l
123.4
116.8
—
9
87
(3026782) Osmolality of Urine
18
168
1.09
0.06
3.1
3.1
mosm/kgh2o
505.2
517.1
0.10
18
143
(3007853) Bacteria identified in Skin by Aerobe culture
10
90
1.12
0.06
1.8
1.4
—
—
—
0
0
(4035726)
10
90
1.12
0.06
1.3
1.5
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
14
151
0.91
0.05
3.8
5.3
%
23.6
21.3
—
9
75
(3023368) Bacteria identified in Blood by Culture
24
229
1.06
0.05
2.7
3.9
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
18
190
0.93
0.04
1.2
1.3
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
39
379
1.05
0.04
7.3
8.5
inr
1.1
1.3
—
8
114
(40758558) Short blood count panel - Blood
21
201
1.06
0.03
6.3
7.8
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
11
102
1.09
0.03
1.9
1.6
—
—
—
0
0
(3022145) Colonoscopy Study observation
10
108
0.92
0.03
1.0
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
16
152
1.06
0.02
3.6
2.9
e6/l
0.8
1.0
—
9
86
(36304419) Bacteria [Presence] in Urine
25
243
1.04
0.01
4.3
3.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
104
1.07
0.01
2.0
1.7
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
30
297
1.01
0.00
3.0
3.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3005532) Lymphocytes/100 leukocytes in Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
68.0
—
0
5
(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035880) pH of Pleural fluid
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(3013727) Leukocytes other/100 leukocytes in Blood
0
6
0.00
0.00
0.0
6.0
—
53.2
—
0
6
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
59
1.02
0.00
13.8
5.9
%
1.1
1.5
—
6
59
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.3
—
37.8
—
0
6
(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
99.8
—
0
5
(3020491) Glucose [Moles/volume] in Blood
0
7
0.00
0.00
0.0
1.7
—
7.4
—
0
7
(4027681)
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.2
—
9.0
—
0
9
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000919) Neutrophils/100 leukocytes in Pleural fluid
0
6
0.00
0.00
0.0
1.2
—
18.3
—
0
6
(4024509)
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
8
0.00
0.00
0.0
3.8
—
—
—
0
0
(3020876) Protein [Mass/time] in 24 hour Urine
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3016018) Differential panel - Cerebral spinal fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(4062490)
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
13.0
—
0
5
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3043410) Blood group antigens tested for on Red Blood Cells
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004451) EKG impression Narrative
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
87
861
1.14
0.00
14.0
11.3
u/l
24.4
23.6
0.24
76
825
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3001893) Eosinophils/100 leukocytes in Pleural fluid
0
5
0.00
0.00
0.0
1.2
—
1.1
—
0
5
(3014271) Vancomycin [Susceptibility]
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000093) Morphology [Interpretation] in Blood Narrative
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(37021550) Renin [Units/volume] in Plasma --upright
0
5
0.00
0.00
0.0
2.0
—
202.9
—
0
5
(3024263) Appearance of Synovial fluid
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint LICHENOID_DRUG_REACTION and mortality.

Females

Parameter HR [95% CI] p-value
LICHENOID_DRUG_REACTION 1.212 [0.91, 1.62] 0.194
Birth year 0.994 [0.99, 1.0] 0.168

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 311 females with LICHENOID_DRUG_REACTION died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have LICHENOID_DRUG_REACTION.

N-year risk Females Males
1 0.102% No data
5 0.546% No data
10 1.518% No data
15 3.23% No data
20 5.826% No data

Relationships between endpoints

Index endpoint: LICHENOID_DRUG_REACTION – Lichenoid drug reaction

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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