≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback
info icon

Malignant neoplasm of peripheral nerves and autonomic nervous system, excluding all cancers (controls excluding all cancers)

Endpoint Browser

C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C47
  • Hospital discharge: ICD-9 — 1928
  • Hospital discharge: ICD-8 — 192[4-5]
  • Cause of death: ICD-10 — C47
  • Cause of death: ICD-9 — 1928
  • Cause of death: ICD-8 — 192[4-5]
  • Cancer registry: Topography ICD-O-3 — C47
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

125

4. Check minimum number of events

None

125

5. Include endpoints

None

125

6. Filter based on genotype QC (FinnGen only)

125

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Malignant neoplasm of peripheral nerves and autonomic nervous system, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 125 63 62
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 52.40 49.90 54.94

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
32
8.13
14.95
1.5
1.2
—
—
—
0
0
67
300
3.66
11.68
2.6
1.6
—
—
—
0
0
26
79
3.89
7.76
1.4
1.1
—
—
—
0
0
86
545
2.85
6.93
10.3
6.1
4.3
4.4
e9/l
0.03
79
458
61
333
2.62
6.52
7.5
8.6
1.2
1.3
inr
0.39
16
99
9
5
19.21
6.36
5.7
1.4
19.3
12.2
ug/l
—
9
5
52
271
2.57
6.01
5.7
2.0
2.3
2.4
mmol/l
0.35
43
230
52
277
2.50
5.69
4.7
3.2
7.4
7.4
ph
—
8
44
52
284
2.42
5.32
4.3
3.3
26.3
44.9
e6/l
0.49
40
213
45
230
2.49
5.32
3.8
3.9
—
—
—
0
0
14
36
4.25
5.14
6.6
6.6
—
—
—
0
0
48
260
2.37
4.94
2.9
2.0
—
—
—
0
0
16
47
3.76
4.93
6.9
7.7
23.4
24.9
mmol/l
1.34
16
41
17
53
3.56
4.82
8.4
7.6
0.6
0.8
%
0.47
17
53
36
175
2.48
4.66
3.6
2.9
549.6
572.8
mosm/kgh2o
0.21
30
144
56
332
2.24
4.60
4.8
3.8
57.6
42.0
e6/l
0.22
43
226
27
117
2.67
4.40
2.0
1.9
—
—
—
0
0
21
80
2.95
4.33
7.9
8.2
—
—
—
0
0
74
502
2.16
4.23
6.2
5.2
1.9
1.9
e9/l
0.10
66
430
12
32
4.04
4.19
3.8
3.0
—
—
—
0
0
16
54
3.25
4.02
8.8
7.6
1.2
1.7
%
0.93
16
54
42
233
2.21
3.96
9.4
4.7
—
—
—
0
0
72
493
2.09
3.91
6.3
5.1
0.6
0.6
e9/l
0.61
63
413
10
25
4.26
3.78
1.3
1.0
—
—
—
0
0
9
16
5.97
3.73
2.2
1.6
—
—
—
0
0
45
263
2.11
3.69
4.8
3.1
0.3
0.3
e6/l
0.01
36
190
19
76
2.77
3.58
6.2
5.7
1.1
1.3
mmol/l
0.75
19
71
71
496
2.00
3.52
6.4
5.1
0.0
0.0
e9/l
1.01
62
415
72
511
1.96
3.35
6.7
5.2
0.2
0.2
e9/l
0.05
64
432
43
255
2.05
3.35
4.7
3.1
—
—
—
0
0
6
7
8.92
3.30
2.3
2.4
4.6
7.3
nmol/l
—
6
7
86
653
2.02
3.25
5.5
3.7
—
—
—
0
0
16
68
2.55
2.68
7.8
9.2
23.9
25.3
mmol/l
1.02
16
68
17
75
2.47
2.65
5.6
4.9
63.4
90.8
ng/l
1.41
17
64
49
327
1.82
2.59
5.1
5.0
—
—
—
0
0
20
99
2.21
2.42
4.8
4.5
—
—
—
0
0
62
453
1.73
2.35
10.2
7.7
0.0
0.0
e9/l
0.49
51
358
6
13
4.79
2.30
2.7
1.3
—
—
—
0
0
6
13
4.79
2.30
2.7
1.5
—
—
—
0
0
90
736
1.80
2.24
3.6
3.8
11.8
10.8
mm/h
0.29
81
671
5
10
5.16
2.09
1.4
2.2
—
—
—
0
0
12
53
2.40
1.87
5.5
3.7
—
—
—
0
0
51
371
1.63
1.87
3.3
3.3
—
—
—
0
0
48
344
1.64
1.86
3.6
3.8
58.3
48.5
ng/l
0.11
32
243
5
12
4.29
1.84
2.8
1.4
—
—
nmol/l
—
0
0
5
12
4.29
1.84
1.4
1.2
—
—
—
0
0
18
96
2.02
1.82
2.7
2.0
394.2
376.0
nmol/l
0.14
18
89
77
626
1.60
1.74
6.0
4.1
—
450.0
—
0
8
5
13
3.96
1.73
1.4
2.7
—
—
—
0
0
38
262
1.65
1.70
4.4
2.8
—
—
—
0
0
14
70
2.13
1.66
1.3
1.3
—
—
—
0
0
5
15
3.43
1.54
3.0
2.6
—
—
—
0
0
40
288
1.57
1.48
3.0
2.2
127.6
167.6
u/l
0.36
40
264
5
16
3.21
1.45
1.8
2.1
18.6
16.8
%
—
5
8
50
384
1.50
1.37
2.1
1.8
83.6
93.5
pmol/l
0.81
24
177
28
190
1.61
1.31
4.9
5.2
—
—
—
0
0
57
454
1.47
1.29
3.8
3.5
0.0
0.0
estimate
—
7
80
58
464
1.47
1.28
3.8
3.5
0.0
0.0
estimate
—
7
74
14
78
1.90
1.27
1.9
2.9
—
—
—
0
0
5
19
2.70
1.22
1.2
2.0
—
—
—
0
0
86
752
1.46
1.14
4.7
3.8
15.1
14.9
pmol/l
0.27
77
679
30
215
1.52
1.12
2.9
3.6
—
—
—
0
0
109
1003
1.68
1.11
19.3
11.4
31.5
23.9
mg/l
1.23
100
737
25
172
1.57
1.11
1.6
1.7
806.5
1200.6
nmol/l
1.84
20
124
56
457
1.41
1.07
5.1
4.8
0.0
0.0
estimate
—
7
79
40
307
1.45
1.07
6.5
3.6
2.2
2.0
ug/l
0.11
34
277
30
223
1.45
0.94
3.1
2.3
388.2
4522.6
umol/l
0.76
25
188
76
667
1.36
0.87
4.6
3.6
—
—
—
0
0
40
318
1.38
0.86
3.9
3.2
6.5
7.7
mmol/l
1.71
34
261
6
31
1.98
0.85
1.3
1.2
—
—
—
0
0
6
31
1.98
0.85
1.5
1.1
—
—
—
0
0
99
910
1.42
0.82
26.4
12.4
38.5
40.2
%
0.95
68
657
6
34
1.80
0.77
6.7
12.0
—
—
—
0
0
9
55
1.68
0.75
1.4
1.2
—
—
—
0
0
12
76
1.64
0.75
4.2
3.8
—
—
—
0
0
7
42
1.71
0.69
1.0
1.2
—
—
—
0
0
5
27
1.89
0.69
1.0
1.1
—
—
—
0
0
5
27
1.89
0.69
3.2
3.3
—
—
—
0
0
34
276
1.32
0.63
4.4
3.6
—
—
—
0
0
0
22
0.00
0.60
0.0
5.6
—
25.8
—
0
13
15
107
1.46
0.58
1.3
1.4
—
—
—
0
0
6
36
1.70
0.57
4.5
1.6
36.2
37.1
nmol/l
—
6
36
111
1059
1.43
0.56
26.2
12.9
79.3
77.4
umol/l
0.26
111
1059
17
126
1.40
0.55
1.5
1.7
—
—
—
0
0
35
292
1.28
0.53
3.1
3.2
90.8
79.3
mg/l
0.08
21
190
27
219
1.30
0.51
1.6
1.5
16.2
21.5
nmol/l
1.48
21
186
13
93
1.44
0.50
1.5
1.3
—
—
—
0
0
7
46
1.55
0.49
3.6
2.9
—
—
—
0
0
12
85
1.46
0.49
1.4
1.4
—
—
—
0
0
97
916
1.26
0.46
5.5
4.5
2.0
1.9
mu/l
0.18
86
822
20
249
0.77
0.46
1.7
1.4
—
—
—
0
0
10
69
1.49
0.46
3.3
2.8
0.2
0.2
g/l
—
10
57
36
309
1.23
0.43
3.5
4.1
12.2
10.5
mg/mmol
0.12
22
199
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
98
931
1.24
0.41
4.1
4.0
1.2
1.2
mmol/l
0.26
87
847
5
34
1.49
0.41
1.2
1.2
0.2
0.2
g/l
—
5
34
5
35
1.45
0.40
1.2
1.2
1.1
1.1
g/l
—
5
35
28
236
1.24
0.39
4.4
3.9
0.0
0.0
estimate
—
7
76
10
72
1.42
0.38
1.0
1.2
—
—
—
0
0
101
967
1.23
0.35
4.5
4.5
4.4
4.6
mmol/l
0.78
94
893
109
1053
1.27
0.34
19.4
10.0
—
—
—
0
0
23
194
1.23
0.32
1.6
1.6
2.0
1.2
mg/l
0.22
13
149
5
71
0.69
0.27
1.2
1.3
—
40.8
—
0
5
99
955
1.18
0.26
4.7
4.4
5.9
6.0
mmol/l
0.47
90
872
9
74
1.23
0.26
1.1
1.4
—
—
—
0
0
5
37
1.37
0.24
8.2
3.2
—
—
—
0
0
23
201
1.18
0.23
1.6
1.7
431250408.2
448.6
pmol/l
0.48
16
157
99
958
1.16
0.23
4.4
4.5
1.4
1.5
mmol/l
0.68
89
879
5
40
1.26
0.22
2.0
2.1
0.9
1.1
%
—
5
40
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
13
151
0.84
0.17
1.5
1.3
26.4
10.1
u/ml
—
5
46
8
95
0.83
0.14
1.9
1.7
—
—
—
0
0
9
105
0.85
0.13
2.4
1.9
—
—
—
0
0
94
919
1.09
0.12
5.4
6.0
38.8
40.2
mmol/mol
0.85
86
851
19
208
0.90
0.11
1.1
1.4
2.0
2.4
g/l
—
8
109
11
96
1.16
0.10
1.8
1.4
—
—
—
0
0
114
1126
1.14
0.09
31.6
16.4
4.5
4.6
e12/l
1.31
109
1086
6
55
1.10
0.09
3.8
8.1
—
—
—
0
0
6
55
1.10
0.09
3.2
2.4
—
—
—
0
0
6
57
1.06
0.08
1.8
2.1
—
—
—
0
0
27
254
1.08
0.08
1.6
1.7
1.4
1.4
mmol/l
0.05
21
209
114
1127
1.13
0.08
31.6
16.4
6.8
6.7
e9/l
0.20
109
1088
6
71
0.84
0.08
6.7
3.8
—
—
—
0
0
32
336
0.94
0.08
3.2
3.2
—
—
—
0
0
9
86
1.05
0.07
1.1
1.2
—
—
—
0
0
11
121
0.90
0.06
1.5
1.2
—
—
—
0
0
18
170
1.07
0.04
2.6
2.5
0.8
0.7
ug/l
—
9
117
26
253
1.03
0.01
4.4
3.1
—
—
—
0
0
99
983
1.03
0.01
5.3
5.0
2.6
2.7
mmol/l
0.72
89
903
17
176
0.96
0.00
2.0
1.8
—
—
—
0
0
13
133
0.97
0.00
2.4
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
12.9
—
0
6
0
6
0.00
0.00
0.0
10.2
—
0.6
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
1868.8
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
391.0
—
0
7
9
97
0.92
0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
11.4
—
1712.8
—
0
5
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
11.0
—
876.8
—
0
5

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_PERIPHERAL_NERVES_AUTONOMIC3_NERVESYSTEM_EXALLC – Malignant neoplasm of peripheral nerves and autonomic nervous system, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).