Fibrosarcoma, excluding all cancers (controls excluding all cancers)

C3_FIBROSARCOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C47.5|C48.5|C49.5
  • Cause of death: ICD-10 C47.5|C48.5|C49.5
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 8810|8811|8814|8815|8821|8830|8832|8840
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

299

4. Check minimum number of events

None

299

5. Include endpoints

None

299

6. Filter based on genotype QC (FinnGen only)

299

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Fibrosarcoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 299 145 154
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 53.27 52.77 53.74

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
230
Matched controls
2300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
47.6
44
*
8832/3-C44.5
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of trunk
+∞
44.2
41
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.8
22.5
61
115
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
22.2
21
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
22.2
21
*
H02AB02
ATC
dexamethasone; systemic
24.3
20.1
28
13
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.4
19.5
37
38
WF003
NOMESCO Finland
Adjuvant radiotherapy
206.1
18.8
19
*
JN4BD
NOMESCO Finland
Extensive body CT
9.8
18.1
37
44
8832/3-C44.7
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of lower limb and hip
+∞
17.9
17
*
C49.25
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip fibrosarcoma
+∞
17.9
17
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
17.9
17
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
16.9
16
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
16.9
16
*
C49.10
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder without histology
+∞
16.9
16
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
16.9
16
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
15.8
15
*
8832/3-C44.6
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of upper limb and shoulder
+∞
15.8
15
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
15.8
15
*
ZZR00
NOMESCO Finland
Flap of skin
34.3
15.1
19
6
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
27.2
15.0
20
8
C49.15
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder fibrosarcoma
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
159.7
14.6
15
*
ZZA00
NOMESCO Finland
Split skin graft
12.0
13.9
25
23
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.1
13.9
26
26
ZZR10
NOMESCO Finland
Flap of skin and muscle
80.0
13.7
15
*
8830/3-C49.2
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
13.7
13
*
C49.21
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip malignant fibrotic histiocytoma
+∞
13.7
13
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
13.7
13
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
14.3
12.7
21
16
C49.11
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder malignant fibrotic histiocytoma
+∞
12.6
12
*
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
+∞
12.6
12
*
8832/3-C44.9
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin, NOS
+∞
12.6
12
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
39.9
12.4
15
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
19.4
12.3
18
10
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
12.2
75
298
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
49.4
12.0
14
*
C49.99
ICD-10 Finland
Malignant tumor in unspecified localization in connective tissue and soft tissue other or unspecified tumor
+∞
11.6
11
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
11.6
11
*
8811/3-C49.2
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
11.6
11
*
C49.39
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax other or unspecified tumor
+∞
11.6
11
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
11.6
11
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
10.3
10.5
20
21
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
10.5
10
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
10.5
10
*
8830/3-C49.1
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
10.5
10
*
8830/3-C49.6
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of trunk, NOS
+∞
10.5
10
*
JN4CD
NOMESCO Finland
Very extensive body CT
9.1
10.3
21
25
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
14.2
9.8
16
12
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
11.4
9.5
17
16
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
9.4
9
*
C49.2
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of lower limb, including hip
+∞
9.4
9
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
9.4
9
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
9.4
9
*
8810/3-C49.1
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
9.4
9
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
9.4
9
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
+∞
9.4
9
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.4
9.0
23
39
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
8.8
113
670
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
8.8
69
314
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
8.6
25
50
WF002
NOMESCO Finland
Radical radiotherapy
93.3
8.5
9
*
116
Kela drug reimbursment
Prostate cancer
+∞
8.4
8
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.4
8
*
8811/3-C49.1
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
8.4
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
C49.30
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax without histology
+∞
8.4
8
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
+∞
8.4
8
*
8810/3-C49.2
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
8.4
8
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
8.4
8
*
C49.35
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thoracic fibrosarcoma
+∞
8.4
8
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
12.3
8.2
14
12
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
10.6
8.2
15
15
HA1AA
NOMESCO Finland
X-ray mammography
10.6
8.2
15
15
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
23.0
8.1
11
5
A04AA01
ATC
ondansetron; systemic, rectal
10.6
7.6
14
14
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
26.0
7.6
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
7.4
46
181
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
A04AD12
ATC
aprepitant; systemic
+∞
7.3
7
*
C49.28
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip Ewing's sarcoma
+∞
7.3
7
*
Z42.2
ICD-10 Finland
Follow-up care involving plastic surgery of other parts of trunk
+∞
7.3
7
*
C49.00
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck without histology
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
+∞
7.3
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.3
7
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
7.3
7
*
8811/3-C49.5
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of pelvis
+∞
7.3
7
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
7.3
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
7.4
7.1
16
23
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
17.3
6.8
10
6
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
41.3
6.8
8
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
41.3
6.8
8
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
8.2
6.7
14
18
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.6
6.6
22
52
JN4AD
NOMESCO Finland
Body CT examination
6.0
6.6
17
30
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
14.9
6.5
10
7
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.1
6.4
19
40
L02BG04
ATC
letrozole; oral
18.6
6.3
9
5
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
159
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
C49.59
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the pelvis other or unspecified tumor
+∞
6.3
6
*
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
C49.45
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of abdominal fibrosarcoma
+∞
6.3
6
*
L02BA01
ATC
tamoxifen; oral
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
6.3
6
*
C49.1
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of upper limb, including shoulder
+∞
6.3
6
*
17131
ICD-8 Finland
Malignant neoplasm of connective and other soft tissue, Lower limb (including hip)
+∞
6.3
6
*
NE1CM
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
58
14.32
66.09
1.5
1.3
—
—
—
0
0
143
669
3.18
21.36
2.7
1.6
—
—
—
0
0
56
147
4.46
20.00
1.5
1.1
—
—
—
0
0
13
13
10.41
11.41
1.4
1.0
—
—
—
0
0
36
120
3.27
8.93
4.2
1.5
4.5
2.8
ug/l
0.39
27
90
105
652
1.94
6.56
2.3
2.0
—
—
—
0
0
168
1220
1.86
6.41
11.8
6.5
3.9
4.3
e9/l
1.69
152
1057
10
9
11.44
5.83
2.1
1.4
13.6
12.3
ug/l
—
10
9
156
1138
1.78
5.59
9.5
3.8
13.0
12.8
umol/l
0.03
150
1063
24
86
2.95
5.28
1.2
1.2
—
—
—
0
0
215
1744
1.83
5.17
9.8
5.2
80.5
76.9
u/l
0.68
206
1587
131
935
1.71
4.87
6.1
9.9
1.0
1.3
inr
10.75
32
251
135
994
1.65
4.33
6.1
5.4
1.2
1.2
mmol/l
0.18
126
887
89
588
1.73
4.28
4.4
3.9
—
—
—
0
0
103
722
1.65
3.92
6.0
5.5
—
—
—
0
0
136
1027
1.59
3.80
6.1
5.3
57.0
57.2
%
0.06
130
953
57
345
1.81
3.66
1.9
1.8
—
—
—
0
0
136
1037
1.57
3.59
6.4
5.6
27.4
28.0
%
0.22
130
960
144
1119
1.55
3.46
6.3
5.4
1.7
1.9
e9/l
2.69
129
976
141
1095
1.54
3.37
6.4
5.3
0.6
0.6
e9/l
0.63
127
936
141
1098
1.54
3.31
6.7
6.0
1.2
1.2
mmol/l
0.99
122
945
132
1018
1.53
3.22
6.6
5.7
8.9
8.7
%
0.36
126
945
44
257
1.83
3.16
5.2
6.2
0.9
1.7
mmol/l
0.71
34
204
76
519
1.62
3.13
12.5
5.1
—
—
—
0
0
131
1014
1.52
3.11
6.4
5.4
3.0
2.9
%
0.21
125
936
140
1102
1.51
3.06
6.4
5.3
0.0
0.0
e9/l
0.15
125
947
127
987
1.50
2.91
6.5
5.4
0.7
0.7
%
0.85
121
909
7
14
5.09
2.74
1.0
1.0
—
—
—
0
0
142
1140
1.47
2.72
6.6
5.6
0.2
0.2
e9/l
0.29
126
1000
31
174
1.87
2.54
2.8
2.0
0.2
0.2
g/l
0.11
31
154
165
1377
1.44
2.51
4.1
4.1
6.5
6.8
mmol/l
1.72
159
1284
8
21
3.88
2.48
1.8
3.7
—
—
—
0
0
26
142
1.91
2.32
2.8
4.2
0.1
0.0
%
—
10
27
7
18
3.95
2.26
1.9
4.5
—
—
—
0
0
27
151
1.87
2.25
2.9
4.1
1.1
0.8
%
0.24
11
32
25
138
1.89
2.17
2.9
4.3
0.0
0.0
%
—
9
24
43
281
1.62
2.10
4.2
5.8
105.1
104.1
mmol/l
1.11
43
269
9
32
2.87
2.01
1.3
1.3
—
—
—
0
0
85
650
1.43
2.00
5.1
3.2
7.4
7.4
ph
0.17
22
106
5
11
4.60
1.95
4.8
1.8
2.8
4.8
nmol/l
—
5
11
38
246
1.62
1.93
3.1
2.3
13.5
9.3
umol/l
0.36
32
214
119
970
1.38
1.92
11.5
8.1
0.0
0.0
e9/l
0.40
106
778
24
137
1.82
1.90
3.0
4.2
0.8
0.3
%
—
8
23
22
128
1.78
1.65
4.8
8.8
24.8
25.3
mmol/l
0.29
22
128
193
1726
1.33
1.58
3.6
4.1
11.3
12.0
mm/h
0.32
174
1582
68
521
1.40
1.56
1.4
1.3
—
—
—
0
0
89
715
1.35
1.53
6.8
2.1
2.4
2.4
mmol/l
0.07
78
599
9
37
2.48
1.49
1.9
3.2
—
—
—
0
0
9
37
2.48
1.49
1.3
1.4
—
—
—
0
0
19
110
1.78
1.46
6.7
8.3
—
—
—
0
0
85
683
1.34
1.45
2.5
3.0
70.1
136.7
e6/l
0.27
69
526
6
22
2.76
1.44
1.8
4.2
0.7
0.6
%
—
6
16
86
695
1.33
1.41
3.7
4.0
—
—
—
0
0
38
266
1.49
1.41
1.6
1.7
—
—
—
0
0
61
468
1.38
1.39
4.4
4.0
—
—
—
0
0
248
2321
1.40
1.39
17.4
12.8
24.1
24.0
mg/l
0.02
203
1794
257
2425
1.43
1.32
15.2
12.0
—
—
—
0
0
32
221
1.50
1.28
1.6
1.3
—
—
—
0
0
183
1653
1.28
1.25
3.5
3.9
—
—
—
0
0
8
38
2.13
1.19
1.8
4.0
—
—
—
0
0
28
191
1.51
1.19
5.2
6.2
1.3
1.4
mmol/l
0.21
28
182
208
2232
0.78
1.19
5.9
6.1
39.6
40.4
mmol/mol
0.96
193
2068
20
127
1.62
1.14
6.0
8.3
0.7
0.7
%
0.19
20
127
7
31
2.29
1.11
1.0
1.7
—
—
—
0
0
24
161
1.53
1.10
3.7
4.5
—
—
—
0
0
76
624
1.29
1.10
2.6
2.8
0.6
0.5
e6/l
0.22
63
462
29
398
0.70
1.03
1.3
1.3
21.3
34.2
iu/ml
—
5
134
7
34
2.08
1.03
2.6
3.4
3.3
5.0
e9/l
—
7
34
55
437
1.32
1.02
2.1
2.5
568.3
542.7
mosm/kgh2o
0.38
49
358
7
35
2.02
1.00
2.7
3.9
56.6
60.7
%
—
7
35
171
1559
1.23
0.97
3.4
4.1
—
—
—
0
0
24
167
1.48
0.95
4.6
3.3
—
—
—
0
0
71
596
1.25
0.86
2.7
2.8
—
—
—
0
0
92
797
1.22
0.84
2.7
3.5
479.6
77.6
e6/l
0.54
71
566
19
130
1.49
0.83
6.4
8.2
1.3
1.5
%
0.51
19
130
14
89
1.60
0.82
2.0
2.1
—
—
—
0
0
21
147
1.46
0.82
2.7
2.8
3.7
4.1
e9/l
0.35
15
112
10
58
1.75
0.80
1.2
1.1
—
—
—
0
0
38
476
0.77
0.77
1.9
1.7
1193.7
1232.9
nmol/l
0.09
29
369
10
60
1.69
0.73
2.9
4.6
—
—
—
0
0
25
186
1.38
0.73
6.0
6.7
—
—
—
0
0
12
76
1.60
0.73
1.1
1.2
—
—
—
0
0
18
248
0.71
0.69
1.7
1.6
—
—
—
0
0
44
531
0.80
0.67
1.4
1.7
467.3
431.5
pmol/l
0.24
36
431
16
112
1.45
0.65
1.2
1.2
—
—
—
0
0
82
722
1.19
0.63
2.4
2.1
60.5
56.2
u/l
0.31
75
667
14
198
0.69
0.62
1.3
1.5
—
—
—
0
0
56
476
1.22
0.62
1.9
2.2
3.9
5.8
e6/l
1.21
50
407
19
139
1.39
0.62
1.7
1.5
—
—
—
0
0
25
319
0.76
0.60
1.4
1.3
905.0
506.2
titre
—
8
78
105
948
1.17
0.60
2.5
2.6
242.2
123.0
ug/l
1.03
95
866
17
123
1.41
0.59
1.1
1.3
75.0
120.8
iu/ml
—
5
51
26
203
1.31
0.58
1.2
1.4
—
—
—
0
0
34
413
0.80
0.56
1.5
1.3
2.5
2.6
g/l
0.18
22
255
231
2393
0.85
0.54
4.5
5.2
2.7
2.7
mmol/l
0.20
209
2193
15
108
1.41
0.54
2.6
6.3
—
—
—
0
0
29
233
1.27
0.53
1.1
1.5
—
—
—
0
0
28
344
0.79
0.51
24.4
24.9
—
1.3
—
0
54
7
48
1.47
0.47
2.1
3.0
5.3
5.1
kpa
—
7
48
7
48
1.47
0.47
2.1
3.0
8.3
8.2
kpa
—
7
48
40
468
0.83
0.47
1.3
1.2
0.6
1.6
u/ml
—
8
137
7
50
1.41
0.45
1.0
1.8
0.7
0.8
nmol/l
—
7
41
16
121
1.34
0.45
3.1
3.8
—
—
—
0
0
34
286
1.21
0.44
2.3
2.3
19.4
23.7
%
1.28
29
253
5
31
1.62
0.43
1.6
1.4
162.4
63.0
pmol/l
—
5
31
21
167
1.28
0.43
1.3
1.5
—
—
—
0
0
6
93
0.64
0.43
4.2
9.0
—
—
—
0
0
8
56
1.44
0.43
7.3
4.3
1.2
1.6
mg/l
—
8
51
8
58
1.39
0.42
4.1
3.1
—
—
—
0
0
32
269
1.21
0.42
2.1
2.3
1.9
1.7
%
0.47
26
241
0
15
0.00
0.41
0.0
1.8
—
65.0
—
0
9
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
11
148
0.73
0.39
4.5
1.4
—
—
—
0
0
5
36
1.40
0.38
1.0
1.2
—
—
—
0
0
65
586
1.14
0.38
4.5
4.0
0.0
0.0
estimate
0.00
25
170
16
125
1.30
0.37
1.0
1.3
—
—
—
0
0
33
282
1.19
0.37
1.7
1.8
—
—
—
0
0
82
752
1.12
0.37
2.9
3.2
30.7
140.0
mg/l
0.70
53
489
26
217
1.22
0.37
4.2
3.6
—
—
—
0
0
12
157
0.75
0.37
2.4
2.6
—
—
—
0
0
10
134
0.74
0.35
3.1
1.7
—
—
—
0
0
16
200
0.79
0.35
2.6
1.8
320.6
378.9
nmol/l
0.62
16
182
91
978
0.90
0.34
3.0
3.7
21.6
43.2
ng/l
3.46
66
698
255
2496
1.15
0.33
13.1
8.8
27.9
25.6
u/l
1.20
245
2392
7
53
1.33
0.31
2.9
2.3
—
—
—
0
0
17
206
0.81
0.30
4.4
3.0
—
—
—
0
0
85
796
1.09
0.26
3.6
3.9
4.9
30.0
mg/mmol
0.59
57
507
17
142
1.21
0.25
1.1
1.2
—
—
—
0
0
9
75
1.21
0.25
1.0
1.2
—
—
—
0
0
229
2338
0.91
0.24
4.2
4.6
4.6
4.6
mmol/l
0.15
210
2151
84
791
1.09
0.23
2.9
3.1
7.7
7.8
mmol/l
0.01
74
666
10
79
1.28
0.22
1.7
1.8
—
—
—
0
0
181
1758
1.07
0.22
3.6
3.7
15.0
14.9
pmol/l
0.10
164
1581
16
188
0.84
0.22
3.9
4.0
89.4
81.0
ng/l
0.19
16
170
228
2324
0.92
0.21
4.4
4.7
5.9
6.0
mmol/l
0.66
208
2103
227
2314
0.92
0.21
4.1
4.6
1.4
1.5
mmol/l
1.63
207
2112
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
16.1
—
880.7
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
26.4
—
1604.2
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.8
—
23.5
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
54
501
1.10
0.21
1.8
1.7
1.1
1.1
mg/l
0.05
43
381
0
13
0.00
0.21
0.0
3.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
48
1.26
0.20
1.2
1.3
—
—
—
0
0
50
539
0.91
0.20
3.7
3.6
—
—
—
0
0
46
497
0.91
0.19
3.5
3.9
28.5
365.1
ng/l
1.92
36
399
263
2598
1.10
0.18
25.7
18.5
4.5
4.5
e12/l
0.12
257
2507
16
138
1.17
0.18
1.1
1.2
286.2
167.7
u/ml
0.41
16
122
263
2599
1.10
0.17
25.7
18.5
7.2
6.7
e9/l
0.45
257
2510
58
616
0.93
0.17
2.7
2.4
343.5
8664.6
umol/l
3.16
51
535
12
101
1.20
0.17
2.8
4.3
—
—
—
0
0
91
871
1.06
0.16
4.8
3.8
2.5
2.0
ug/l
0.56
79
767
65
684
0.94
0.15
2.9
3.1
—
—
—
0
0
13
150
0.86
0.15
1.2
1.2
—
—
—
0
0
23
208
1.11
0.14
1.7
1.4
—
—
—
0
0
8
96
0.83
0.14
1.0
1.1
—
—
—
0
0
13
148
0.87
0.13
1.4
1.3
—
—
—
0
0
114
1108
1.05
0.12
3.5
3.7
0.0
0.0
estimate
0.00
26
175
262
2596
1.07
0.12
25.7
18.5
246.6
246.7
e9/l
0.00
256
2516
22
239
0.91
0.11
2.0
2.3
95.4
158.6
ug/g
0.90
22
187
212
2092
1.05
0.10
19.4
13.7
39.9
40.0
%
0.07
144
1456
14
125
1.13
0.10
4.0
3.2
4.5
4.8
pmol/l
0.64
14
111
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
45
1.11
0.10
1.6
1.6
51.8
62.8
%
—
5
45
35
370
0.94
0.09
1.3
1.3
1.1
6.9
u/ml
1.62
12
147
33
311
1.07
0.09
1.3
1.2
—
—
—
0
0
79
815
0.96
0.09
2.8
3.0
—
—
—
0
0
222
2243
0.96
0.08
3.7
4.2
1.4
1.3
mmol/l
1.44
203
2033
5
64
0.78
0.08
7.8
1.3
27.5
30.5
mg/l
—
5
55
5
64
0.78
0.08
7.8
1.3
39.9
43.8
mg/l
—
5
56
8
78
1.03
0.07
1.7
1.6
—
—
—
0
0
7
85
0.82
0.07
1.1
1.2
—
0.2
—
0
6
212
2140
0.97
0.07
4.4
4.6
1.8
2.5
mu/l
0.66
195
1928
61
594
1.03
0.05
3.4
3.3
—
—
—
0
0
114
1124
1.02
0.04
3.5
3.7
0.0
0.0
estimate
0.50
24
168
112
1106
1.02
0.03
4.4
5.0
0.0
0.0
estimate
0.00
24
168
13
122
1.07
0.02
1.2
3.0
0.3
0.2
e6/l
0.07
13
116
28
271
1.04
0.02
1.3
1.4
—
—
—
0
0
58
586
0.99
0.00
2.1
2.1
3.0
3.0
mg/l
0.01
50
496
12
122
0.98
0.00
2.4
2.5
—
—
—
0
0
58
581
1.00
0.00
1.4
1.5
23.6
21.4
nmol/l
0.36
51
495
49
485
1.01
0.00
2.6
2.6
0.6
0.7
ug/l
0.94
34
313
100
1003
1.00
0.00
1.9
2.0
101.6
94.2
pmol/l
0.84
58
501
24
236
1.02
0.00
2.5
3.6
—
—
—
0
0
5
56
0.89
0.00
1.4
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
11.6
—
0.8
—
0
9
0
9
0.00
0.00
0.0
5.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
173.0
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.4
1.2
—
—
—
0
0
5
55
0.91
0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
5
58
0.86
0.00
1.6
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
7.8
—
—
—
0
0
0
8
0.00
0.00
0.0
5.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
17.1
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.1
—
1.2
—
0
8
0
5
0.00
0.00
0.0
8.6
—
—
—
0
0
60
600
1.00
0.00
1.6
1.6
1.4
1.4
mmol/l
0.05
52
490
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
22.7
—
0
8
0
8
0.00
0.00
0.0
1.0
—
2.8
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_FIBROSARCOMA_EXALLC – Fibrosarcoma, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).