No definition available.
Fibrosarcoma, excluding all cancers (controls excluding all cancers)
C3_FIBROSARCOMA_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
299 |
4. Check minimum number of eventsNone |
299 |
5. Include endpointsNone |
299 |
6. Filter based on genotype QC (FinnGen only) |
299 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Fibrosarcoma, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 299 | 145 | 154 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | 53.27 | 52.77 | 53.74 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 230
- Matched controls
- 2300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
47.6
44
*
8832/3-C44.5
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of trunk
+∞
44.2
41
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.8
22.5
61
115
C49.29
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip other or unspecified tumor
+∞
22.2
21
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
22.2
21
*
H02AB02
ATC
dexamethasone; systemic
24.3
20.1
28
13
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.4
19.5
37
38
WF003
NOMESCO Finland
Adjuvant radiotherapy
206.1
18.8
19
*
JN4BD
NOMESCO Finland
Extensive body CT
9.8
18.1
37
44
8832/3-C44.7
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of lower limb and hip
+∞
17.9
17
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
17.9
17
*
C49.25
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip fibrosarcoma
+∞
17.9
17
*
C49.10
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder without histology
+∞
16.9
16
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
16.9
16
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
16.9
16
*
C49.20
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the lower extremity including the hip without histology
+∞
16.9
16
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
15.8
15
*
8832/3-C44.6
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin of upper limb and shoulder
+∞
15.8
15
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
15.8
15
*
ZZR00
NOMESCO Finland
Flap of skin
34.3
15.1
19
6
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
27.2
15.0
20
8
C49.15
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder fibrosarcoma
+∞
14.7
14
*
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
159.7
14.6
15
*
ZZA00
NOMESCO Finland
Split skin graft
12.0
13.9
25
23
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.1
13.9
26
26
ZZR10
NOMESCO Finland
Flap of skin and muscle
80.0
13.7
15
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
13.7
13
*
C49.21
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip malignant fibrotic histiocytoma
+∞
13.7
13
*
8830/3-C49.2
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
13.7
13
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
14.3
12.7
21
16
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
+∞
12.6
12
*
8832/3-C44.9
ICD-O-3
Dermatofibrosarcoma protuberans, fibrosarcomatous of skin, NOS
+∞
12.6
12
*
C49.11
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder malignant fibrotic histiocytoma
+∞
12.6
12
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
39.9
12.4
15
*
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
19.4
12.3
18
10
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
12.2
75
298
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
49.4
12.0
14
*
8811/3-C49.2
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
11.6
11
*
C49.99
ICD-10 Finland
Malignant tumor in unspecified localization in connective tissue and soft tissue other or unspecified tumor
+∞
11.6
11
*
C49.39
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax other or unspecified tumor
+∞
11.6
11
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
11.6
11
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
11.6
11
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
10.3
10.5
20
21
8830/3-C49.1
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
10.5
10
*
8830/3-C49.6
ICD-O-3
Malignant fibrous histiocytoma of connective, Subcutaneous and other soft tissues of trunk, NOS
+∞
10.5
10
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
10.5
10
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
10.5
10
*
JN4CD
NOMESCO Finland
Very extensive body CT
9.1
10.3
21
25
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
14.2
9.8
16
12
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
11.4
9.5
17
16
C49.2
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of lower limb, including hip
+∞
9.4
9
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
+∞
9.4
9
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
9.4
9
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
9.4
9
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
9.4
9
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
9.4
9
*
8810/3-C49.1
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
9.4
9
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.4
9.0
23
39
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
8.8
113
670
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
8.8
69
314
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
8.6
25
50
WF002
NOMESCO Finland
Radical radiotherapy
93.3
8.5
9
*
8810/3-C49.2
ICD-O-3
Fibrosarcoma, NOS, of connective, Subcutaneous and other soft tissues of lower limb and hip
+∞
8.4
8
*
C49.35
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thoracic fibrosarcoma
+∞
8.4
8
*
116
Kela drug reimbursment
Prostate cancer
+∞
8.4
8
*
8811/3-C49.1
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of upper limb and shoulder
+∞
8.4
8
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.4
8
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
8.4
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
C49.30
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the thorax without histology
+∞
8.4
8
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
+∞
8.4
8
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
12.3
8.2
14
12
HA1AA
NOMESCO Finland
X-ray mammography
10.6
8.2
15
15
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
10.6
8.2
15
15
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
23.0
8.1
11
5
A04AA01
ATC
ondansetron; systemic, rectal
10.6
7.6
14
14
NB1DG
NOMESCO Finland
Shoulder and humerus very extensive MRI examination with high intensity magnet
26.0
7.6
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
7.4
46
181
C49.00
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the head, face and neck without histology
+∞
7.3
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.3
7
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
7.3
7
*
WF001
NOMESCO Finland
Preoperative radiotherapy
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
A04AD12
ATC
aprepitant; systemic
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
L01BC06
ATC
capecitabine; oral
+∞
7.3
7
*
8811/3-C49.5
ICD-O-3
Myxofibrosarcoma of connective, Subcutaneous and other soft tissues of pelvis
+∞
7.3
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.3
7
*
C49.28
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of lower extremity including hip Ewing's sarcoma
+∞
7.3
7
*
Z42.2
ICD-10 Finland
Follow-up care involving plastic surgery of other parts of trunk
+∞
7.3
7
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
+∞
7.3
7
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
7.4
7.1
16
23
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.2
6.9
20
41
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
17.3
6.8
10
6
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
41.3
6.8
8
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
41.3
6.8
8
*
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
8.2
6.7
14
18
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.6
6.6
22
52
JN4AD
NOMESCO Finland
Body CT examination
6.0
6.6
17
30
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
14.9
6.5
10
7
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.1
6.4
19
40
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
6.4
36
132
L02BG04
ATC
letrozole; oral
18.6
6.3
9
5
17131
ICD-8 Finland
Malignant neoplasm of connective and other soft tissue, Lower limb (including hip)
+∞
6.3
6
*
C49.45
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of abdominal fibrosarcoma
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
159
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
L02BA01
ATC
tamoxifen; oral
+∞
6.3
6
*
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
C49.1
ICD-10 Finland
Malignant neoplasm: Connective and soft tissue of upper limb, including shoulder
+∞
6.3
6
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
NE1CM
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
C49.59
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of the pelvis other or unspecified tumor
+∞
6.3
6
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
6.3
6
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
6.3
6
*
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_FIBROSARCOMA_EXALLC – Fibrosarcoma, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).