No definition available.
Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, excluding all cancers (controls excluding all cancers)
C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
291 |
4. Check minimum number of eventsNone |
291 |
5. Include endpointsNone |
291 |
6. Filter based on genotype QC (FinnGen only) |
291 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 291 | 153 | 138 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | 52.96 | 47.51 | 59.00 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 62
- Matched controls
- 621
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
32.1
28
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
27.1
24
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
23.4
21
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
18.7
17
*
H02AB02
ATC
dexamethasone; systemic
76.4
15.7
17
*
130
Kela drug reimbursment
Malignant tumour
+∞
15.2
14
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
15.2
14
*
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
15.2
14
*
M03BX01
ATC
baclofen; systemic
146.0
11.9
12
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
73.0
11.1
12
*
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
131.3
10.8
11
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
+∞
9.6
9
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
9.6
9
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
32.8
8.8
11
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
103.6
8.6
9
*
D33.43
ICD-10 Finland
Spinal cord
+∞
8.5
8
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
8.5
8
*
JN4BD
NOMESCO Finland
Extensive body CT
14.6
8.0
13
11
L28
ICPC
Limited function/disability (L)
6.5
7.7
21
45
WF002
NOMESCO Finland
Radical radiotherapy
+∞
7.4
7
*
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
7.4
7
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
23.4
7.4
10
5
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
7.3
30
103
N03AX16
ATC
pregabalin; oral
4.9
7.2
27
84
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
13.2
7.2
12
11
XKD06
NOMESCO Finland
Physiologic investigation of micturition
19.5
7.0
10
6
XX3DW
NOMESCO Finland
Time consuming IT work
14.5
6.9
11
9
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
9.2
6.9
14
19
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
8.2
6.9
15
23
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
6.3
6
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.3
6.3
20
51
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
9.6
6.2
12
15
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
8.3
6.1
13
19
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
16
14.79
23.90
2.3
4.0
—
—
—
0
0
20
23
9.26
16.08
2.3
1.2
—
—
—
0
0
62
205
3.57
15.90
5.8
9.6
1.5
1.4
mmol/l
0.05
49
161
14
12
12.21
13.62
1.9
1.2
—
—
—
0
0
162
1010
2.36
11.63
7.8
6.0
1.2
1.2
mmol/l
3.01
143
868
24
49
5.25
11.42
2.4
1.2
1819.6
331.8
e6/l
0.42
17
39
24
49
5.25
11.42
2.2
1.1
10.1
4.3
e6/l
0.42
16
38
143
900
2.16
9.40
6.8
5.8
1.2
1.2
mmol/l
1.69
137
803
10
11
9.38
8.13
2.2
1.4
3.0
1.8
mmol/l
—
10
11
135
900
1.93
6.96
4.1
3.7
—
—
—
0
0
106
651
1.99
6.95
4.8
2.0
2.3
2.4
mmol/l
0.58
95
538
82
467
2.05
6.59
2.4
1.9
—
—
—
0
0
161
1155
1.88
6.48
13.8
6.2
3.8
4.2
e9/l
2.05
140
1001
15
36
4.34
5.89
1.6
1.3
—
—
—
0
0
15
36
4.34
5.89
1.6
1.3
—
—
—
0
0
170
1280
1.79
5.49
6.2
4.3
6.6
6.7
mmol/l
0.34
160
1187
5
0
+∞
5.22
1.0
0.0
—
—
—
0
0
106
718
1.75
4.77
3.9
2.9
—
—
—
0
0
53
299
1.94
4.25
1.8
1.7
—
—
—
0
0
85
560
1.73
4.13
4.0
2.7
0.5
0.5
e6/l
0.08
69
400
27
120
2.38
3.94
1.2
1.6
—
—
—
0
0
194
2229
0.61
3.66
4.1
4.5
4.5
4.6
mmol/l
0.81
169
2076
190
2193
0.62
3.64
4.5
4.5
5.9
6.0
mmol/l
0.66
170
2008
200
2273
0.62
3.44
4.5
4.9
2.7
2.7
mmol/l
0.33
180
2106
193
2210
0.62
3.41
4.1
4.4
1.4
1.5
mmol/l
1.79
169
2050
55
343
1.74
3.19
3.5
2.4
0.9
1.5
e6/l
0.96
37
178
38
212
1.91
3.15
1.8
1.8
—
—
—
0
0
7
12
5.95
3.04
1.1
1.2
363.4
179.5
u/l
—
7
12
6
9
6.78
2.88
1.2
1.1
12.2
6.9
u/l
—
6
9
37
212
1.85
2.84
1.9
1.7
—
—
—
0
0
10
31
3.31
2.80
1.2
1.2
—
—
—
0
0
25
126
2.08
2.75
1.3
1.5
—
—
—
0
0
42
254
1.76
2.71
2.0
2.3
23.9
24.7
%
0.08
36
226
6
10
6.10
2.71
1.2
1.1
12.0
15.4
u/l
—
6
10
13
49
2.73
2.66
2.5
3.6
—
—
—
0
0
187
1595
1.48
2.61
10.8
5.3
81.5
75.8
u/l
1.19
181
1464
188
2119
0.68
2.44
3.7
4.0
1.3
1.3
mmol/l
0.08
166
1952
9
27
3.41
2.41
1.2
1.1
—
—
—
0
0
162
1365
1.42
2.28
6.9
4.0
—
2705.7
—
0
19
55
376
1.57
2.24
4.2
2.1
2.5
2.4
mmol/l
0.55
50
313
47
312
1.60
2.16
2.1
2.1
12.5
14.1
umol/l
0.63
42
280
48
321
1.59
2.14
3.8
2.7
2.1
2.8
e6/l
0.32
30
154
42
272
1.64
2.13
10.0
7.3
—
—
—
0
0
42
275
1.62
2.04
1.9
2.1
2.4
2.3
g/l
0.38
37
256
9
32
2.87
2.02
1.2
1.5
—
—
—
0
0
5
11
4.60
1.95
4.2
2.8
—
—
—
0
0
41
592
0.64
1.88
1.6
1.7
1.4
1.4
mmol/l
0.07
36
501
11
46
2.45
1.87
3.0
1.6
—
—
—
0
0
27
162
1.73
1.82
1.7
1.8
68.6
67.6
ml/min/173m2
—
5
71
8
29
2.81
1.80
1.1
1.1
—
—
—
0
0
8
30
2.71
1.73
1.1
1.1
—
—
—
0
0
6
20
3.04
1.59
1.0
1.3
—
—
—
0
0
24
149
1.67
1.46
3.4
2.2
10.3
14.4
nmol/l
1.61
19
140
5
16
3.16
1.44
1.2
1.0
—
—
—
0
0
25
158
1.64
1.43
1.2
1.3
—
36.0
—
0
10
5
17
2.97
1.36
1.0
1.1
—
—
—
0
0
5
17
2.97
1.36
2.0
1.6
—
—
—
0
0
5
17
2.97
1.36
1.0
1.3
—
—
—
0
0
6
24
2.53
1.31
1.2
1.1
—
—
—
0
0
191
2070
0.78
1.24
5.1
5.9
38.6
40.0
mmol/mol
1.43
176
1930
5
20
2.53
1.15
1.0
1.2
—
—
—
0
0
122
1387
0.79
1.15
3.0
3.1
—
—
—
0
0
5
21
2.40
1.09
2.6
1.5
—
—
—
0
0
26
179
1.50
1.07
4.7
2.9
—
—
—
0
0
79
656
1.28
1.06
2.2
2.2
55.6
56.2
u/l
0.07
69
606
63
508
1.31
1.05
2.2
2.0
3.9
3.0
mg/l
1.03
54
430
9
49
1.86
0.99
1.2
1.3
—
—
—
0
0
5
23
2.19
0.98
1.4
1.2
—
—
—
0
0
0
30
0.00
0.98
0.0
1.0
—
—
—
0
0
17
109
1.59
0.96
1.8
1.7
—
—
—
0
0
10
55
1.85
0.93
1.1
1.3
—
—
—
0
0
100
867
1.23
0.92
4.2
3.5
637.5
87.4
ng/l
0.43
72
591
6
29
2.09
0.90
1.8
1.2
—
—
—
0
0
8
43
1.88
0.88
3.8
4.2
2.8
3.8
g/l
—
8
43
10
57
1.78
0.84
1.1
1.1
—
—
—
0
0
47
579
0.78
0.84
3.5
3.4
20.4
25.2
%
1.40
19
260
8
47
1.72
0.81
1.3
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.7
—
—
—
0
0
25
334
0.72
0.78
1.6
1.5
—
—
—
0
0
65
548
1.24
0.77
2.3
2.5
330.1
7594.6
umol/l
2.49
53
474
101
895
1.20
0.73
2.4
2.3
76.0
77.2
nmol/l
0.16
91
794
5
25
2.02
0.73
1.0
1.2
—
—
—
0
0
7
42
1.68
0.69
1.1
1.9
—
—
—
0
0
59
505
1.21
0.61
1.6
1.5
21.9
20.4
nmol/l
0.26
50
433
7
111
0.62
0.59
1.1
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.8
—
—
—
0
0
6
37
1.63
0.56
1.2
1.1
—
—
—
0
0
33
402
0.80
0.56
2.6
2.4
0.4
0.8
ug/l
5.97
22
255
231
2390
0.84
0.55
13.8
8.6
26.8
26.5
u/l
0.08
225
2295
76
675
1.17
0.53
3.0
2.7
59.4
33.9
u/l
0.72
69
645
64
724
0.85
0.51
4.4
3.6
3.7
1.9
ug/l
0.50
57
649
7
45
1.57
0.49
2.0
1.9
—
—
—
0
0
18
232
0.76
0.48
1.8
2.1
—
—
—
0
0
36
423
0.83
0.44
4.1
3.7
32.0
241.0
ng/l
2.33
31
323
115
1067
1.13
0.43
5.5
3.3
0.0
0.0
estimate
0.00
25
163
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
52
457
1.17
0.42
1.7
1.7
202273154.5
442.3
pmol/l
0.49
44
388
5
33
1.52
0.41
1.8
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
5
35
1.44
0.39
1.0
1.3
—
—
—
0
0
5
35
1.44
0.39
1.6
1.3
—
—
—
0
0
201
2082
0.89
0.39
19.0
10.4
84.8
80.0
ml/min/173m2
2.32
178
1648
61
548
1.14
0.38
5.7
3.6
0.0
0.0
estimate
0.00
24
158
17
211
0.79
0.36
1.9
2.0
—
—
—
0
0
116
1088
1.11
0.35
5.6
3.3
0.0
0.0
estimate
0.00
24
154
10
73
1.38
0.35
1.9
1.5
—
—
—
0
0
43
379
1.16
0.34
1.4
1.5
—
—
—
0
0
10
76
1.33
0.28
1.9
1.6
—
—
—
0
0
198
2036
0.91
0.27
22.2
12.6
38.9
40.1
%
0.89
134
1460
113
1074
1.09
0.25
7.7
4.6
0.0
0.0
estimate
0.00
24
163
9
77
1.17
0.24
1.4
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
40
437
0.90
0.21
2.0
1.9
0.9
1.1
mg/l
0.77
28
329
16
187
0.85
0.21
1.7
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
203
2074
0.93
0.20
5.4
4.4
2.0
1.9
mu/l
0.20
187
1892
31
282
1.11
0.17
3.9
4.5
30.3
31.9
%
0.43
23
183
5
68
0.73
0.17
1.4
1.3
—
—
—
0
0
8
68
1.18
0.16
1.8
1.8
—
—
—
0
0
88
842
1.06
0.16
5.9
3.4
—
—
—
0
0
6
78
0.76
0.15
1.5
1.5
—
—
—
0
0
174
1703
1.05
0.14
5.1
3.6
14.9
14.7
pmol/l
0.54
163
1535
10
86
1.17
0.11
1.8
1.3
—
—
—
0
0
18
165
1.10
0.09
3.6
4.2
57.4
77.4
ng/l
1.00
12
145
87
893
0.96
0.08
2.1
2.0
90.7
93.9
pmol/l
0.28
48
445
96
937
1.04
0.08
2.6
2.6
130.4
124.0
ug/l
0.09
88
872
6
71
0.84
0.07
1.7
1.5
—
—
—
0
0
6
73
0.82
0.07
1.7
1.5
—
—
—
0
0
7
80
0.87
0.07
1.3
1.9
6.0
2.3
mg/l
—
7
51
62
639
0.96
0.07
4.1
3.0
945.3
1380.3
ng/l
1.02
54
540
167
1650
1.03
0.06
4.1
4.0
15.0
11.7
mm/h
1.19
152
1504
38
395
0.96
0.06
1.6
1.3
18.0
34.5
iu/ml
1.45
13
119
150
1482
1.03
0.05
3.4
3.1
63.9
46.1
u/l
0.75
143
1394
222
2235
0.97
0.05
21.9
11.7
24.1
21.9
mg/l
0.41
197
1710
37
379
0.97
0.02
1.4
1.3
29.1
9.4
u/ml
0.38
11
140
40
409
0.97
0.02
1.9
1.7
1311.1
1175.6
nmol/l
0.35
33
309
12
127
0.94
0.01
1.7
1.7
—
—
—
0
0
11
112
0.98
0.00
1.4
1.3
—
—
—
0
0
11
105
1.05
0.00
1.4
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
9.5
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
0.00
4.4
1.7
224.6
240.9
pmol/l
—
5
45
7
79
0.88
0.00
1.4
1.7
—
144.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
114.0
—
0
6
0
6
0.00
0.00
0.0
6.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
207.3
—
0
9
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
20.6
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.4
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS_EXALLC – Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system, excluding all cancers (controls excluding all cancers)
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).