sweat gland disease: disorders or sweat glands
Apocrine sweat disorders, other sweat gland disorders
DOID EFO Endpoint Browser PheWeb
L12_APOCRINESWEAT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
148 |
4. Check minimum number of eventsNone |
148 |
5. Include endpointsNone |
148 |
6. Filter based on genotype QC (FinnGen only) |
148 |
Control definitions (FinnGen only)
- Control exclude
- L12_DISORDSKINAPPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L60-L75
- Name in latin
- Morbositates glandularum sudoriferarum apocrinarum
Similar endpoints
↥List of similar endpoints to
Apocrine sweat disorders, other sweat gland disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1190 | 653 | 525 |
| Only index persons | 958 | 562 | 396 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 34.11 | 34.20 | 33.83 |
| Only index persons | 32.47 | 32.89 | 31.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 148 | 99 | 49 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 33.90 | 33.41 | 34.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 133
- Matched controls
- 1328
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
70591
ICD-8 Finland
Diseases of sweat glands, Hidrosadenitis
+∞
45.5
41
*
L73.2
ICD-10 Finland
Hidradenitis suppurativa
+∞
25.9
24
*
70590
ICD-8 Finland
Diseases of sweat glands, Hidrosis
+∞
19.2
18
*
L75.9
ICD-10 Finland
Apocrine sweat disorder, unspecified
+∞
14.9
14
*
L75.8
ICD-10 Finland
Other apocrine sweat disorders
+∞
13.8
13
*
7058X
ICD-9 Finland
Disorders of sweat glands, Other specified disorders of sweat glands[MUU HIKIRAUHASSAIRAUS]
+∞
12.7
12
*
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
10.5
8.6
16
17
7058C
ICD-9 Finland
Disorders of sweat glands, Other specified disorders of sweat glands[HIDRADENITIS SUPPURATIVA]
+∞
8.4
8
*
QBE05
NOMESCO Finland
Excision of sweat glands or sweat gland bearing skin from trunk
+∞
8.4
8
*
70599
ICD-8 Finland
Diseases of sweat glands, Other
+∞
8.4
8
*
J01FF01
ATC
clindamycin; systemic
3.0
7.0
49
218
S10
ICPC
Boil/carbuncle
6.3
6.4
16
28
9752
FHL
Surgical treatment of hyperhidrosis
+∞
6.3
6
*
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
9.3
6.2
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
59
366
2.02
4.02
4.0
2.3
57.2
54.9
u/l
0.23
54
341
73
499
1.91
3.67
2.4
2.2
72.8
77.2
nmol/l
0.77
61
437
93
698
1.89
3.42
5.2
4.4
6.8
6.6
mmol/l
0.25
88
634
46
277
1.96
3.31
1.5
1.5
21.7
23.0
nmol/l
0.21
37
219
115
933
2.04
3.27
4.0
3.9
15.0
14.8
pmol/l
0.34
100
842
17
67
2.74
3.26
4.1
3.1
5.4
5.1
kpa
0.72
17
59
100
778
1.88
3.18
4.1
2.9
68.5
45.7
u/l
1.07
92
731
116
951
2.02
3.10
10.2
6.6
82.6
78.0
u/l
0.35
105
883
45
278
1.89
2.97
2.8
2.2
—
—
—
0
0
68
481
1.77
2.87
2.2
1.8
88.3
98.4
pmol/l
0.71
36
218
8
18
4.63
2.84
1.3
1.2
—
—
—
0
0
12
42
3.02
2.82
2.3
2.1
—
—
—
0
0
43
266
1.87
2.81
2.7
1.9
3.0
3.0
mg/l
0.01
36
225
11
38
3.05
2.64
2.5
1.9
—
—
—
0
0
42
269
1.78
2.43
2.0
1.7
0.9
0.9
mg/l
0.11
30
219
18
85
2.27
2.40
1.8
1.4
—
—
—
0
0
109
910
1.75
2.33
5.5
4.0
15.1
11.9
mm/h
1.07
97
826
88
699
1.64
2.23
10.7
8.8
4.5
4.1
e9/l
1.00
80
596
24
132
1.98
2.20
29.5
19.0
1.0
1.3
inr
—
6
16
71
540
1.61
2.11
6.3
5.3
1.2
1.2
mmol/l
0.08
65
494
78
608
1.60
2.08
8.3
6.1
1.2
1.2
mmol/l
0.01
69
525
5
10
5.13
2.08
1.0
1.5
13.5
19.9
ug/l
—
5
10
50
355
1.62
1.94
4.7
3.2
1690.3
1170.8
ng/l
0.63
45
301
18
94
2.04
1.90
3.0
2.9
91.7
73.1
ng/l
0.34
18
81
6
17
3.63
1.85
1.0
1.2
—
—
—
0
0
72
563
1.54
1.83
5.3
4.0
—
—
—
0
0
26
160
1.76
1.70
4.5
4.2
31.4
33.3
%
0.33
17
100
29
186
1.70
1.65
2.6
1.9
—
—
—
0
0
13
64
2.13
1.59
3.4
1.6
—
—
—
0
0
35
239
1.61
1.57
1.8
1.8
373.5
462.7
pmol/l
1.67
30
197
9
38
2.46
1.48
1.4
1.3
—
—
—
0
0
38
269
1.56
1.46
1.4
1.2
0.5
1.8
u/ml
0.96
12
77
54
416
1.47
1.39
3.7
3.1
2.3
2.4
mmol/l
0.51
43
363
6
23
2.67
1.38
3.3
6.2
—
176.8
—
0
5
125
1136
1.65
1.38
6.0
4.7
1.6
3.0
mu/l
0.72
115
1033
6
24
2.56
1.31
1.7
1.6
—
—
—
0
0
5
18
2.84
1.29
1.2
1.1
—
—
—
0
0
9
44
2.11
1.29
1.9
1.4
—
—
—
0
0
6
25
2.46
1.25
1.0
1.6
—
—
—
0
0
31
217
1.54
1.25
1.3
1.3
24.9
33.6
iu/ml
0.37
13
78
60
484
1.40
1.18
7.3
3.8
24.2
36.5
ng/l
0.69
45
342
7
30
2.40
1.14
1.9
2.9
166.7
178.4
%
—
7
30
30
214
1.50
1.11
2.3
1.7
1154.6
1212.2
nmol/l
0.13
23
161
22
146
1.60
1.11
4.4
6.7
107.5
103.9
mmol/l
2.20
22
139
126
1164
1.55
1.10
4.6
4.0
1.5
1.3
mmol/l
2.12
113
1057
11
60
1.90
1.06
1.2
1.0
—
—
—
0
0
128
1194
1.53
0.97
6.0
4.6
6.1
6.0
mmol/l
0.37
115
1092
12
70
1.78
0.96
1.5
1.2
—
—
—
0
0
17
110
1.62
0.95
5.9
3.4
—
—
—
0
0
123
1140
1.47
0.95
7.2
5.9
38.8
39.9
mmol/mol
0.84
111
1056
129
1210
1.52
0.90
5.0
4.5
4.6
4.7
mmol/l
0.79
114
1112
6
30
2.04
0.88
1.2
1.4
—
—
—
0
0
21
148
1.49
0.83
5.0
7.3
—
—
—
0
0
19
131
1.52
0.83
2.6
1.7
—
—
—
0
0
8
47
1.74
0.82
2.5
2.2
—
—
—
0
0
130
1227
1.49
0.81
23.5
13.1
22.1
23.7
mg/l
0.17
111
953
52
432
1.31
0.80
3.6
2.8
—
—
—
0
0
19
133
1.49
0.78
2.6
1.8
—
—
—
0
0
19
133
1.49
0.78
3.3
7.6
4.9
5.2
kpa
0.90
19
125
19
133
1.49
0.78
3.3
7.6
12.0
12.5
kpa
0.14
19
125
5
24
2.12
0.75
1.2
1.5
—
—
—
0
0
53
447
1.29
0.73
4.9
3.9
—
—
—
0
0
59
506
1.28
0.71
3.2
2.4
100.0
117.4
ug/l
0.50
52
454
5
27
1.88
0.69
1.4
1.6
—
—
—
0
0
127
1203
1.39
0.67
4.9
4.5
1.5
1.5
mmol/l
0.94
113
1096
129
1228
1.39
0.63
5.5
5.1
2.7
2.8
mmol/l
0.86
116
1120
27
211
1.34
0.63
1.4
1.3
3.7
11.7
u/ml
1.30
15
80
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
37
305
1.28
0.60
4.0
3.7
0.0
0.0
estimate
0.00
14
102
132
1265
1.40
0.57
24.7
15.3
139.9
139.8
mmol/l
0.10
127
1230
9
64
1.43
0.52
4.0
5.8
22.1
25.2
mmol/l
—
9
64
132
1269
1.37
0.52
24.9
15.4
4.0
4.0
mmol/l
0.57
127
1232
22
173
1.32
0.50
1.8
1.8
30.9
29.2
s
0.59
22
166
5
31
1.63
0.43
3.4
2.5
0.0
0.0
g/l
—
5
31
5
32
1.58
0.42
1.6
1.2
—
—
—
0
0
133
1287
1.33
0.42
25.4
15.7
85.2
74.8
umol/l
0.69
133
1287
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
23
188
1.26
0.40
3.0
2.9
4.7
3.0
e6/l
0.26
12
92
5
35
1.44
0.39
1.0
1.1
—
17.2
—
0
6
65
593
1.17
0.39
4.4
3.8
0.0
0.0
estimate
0.00
15
98
9
70
1.30
0.37
1.8
1.6
—
—
—
0
0
26
219
1.23
0.36
4.3
3.2
24.2
74.0
ng/l
1.13
20
175
134
1303
1.30
0.35
14.6
9.8
26.3
24.7
u/l
0.65
127
1254
10
73
1.40
0.35
2.5
2.9
4.7
4.5
pmol/l
—
10
61
6
43
1.41
0.35
2.7
1.9
—
—
—
0
0
6
43
1.41
0.35
3.0
2.2
9.9
9.4
g/l
—
6
38
64
587
1.16
0.35
6.6
5.4
0.0
0.0
estimate
0.00
16
103
63
578
1.16
0.34
4.2
3.8
0.0
0.0
estimate
0.00
16
100
121
1169
1.19
0.31
22.7
12.6
78.8
80.1
ml/min/173m2
0.27
103
931
7
56
1.26
0.30
6.4
3.6
51.9
47.0
%
—
7
56
38
340
1.16
0.28
3.6
3.0
1.2
0.4
e6/l
0.62
26
239
21
245
0.83
0.27
3.5
4.1
17.2
21.3
%
0.71
11
123
5
38
1.33
0.23
1.0
2.0
—
—
—
0
0
8
103
0.76
0.22
2.3
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
7
60
1.17
0.18
1.1
1.4
—
—
—
0
0
70
732
0.92
0.17
3.2
2.9
—
—
—
0
0
22
198
1.13
0.15
1.4
1.5
—
—
—
0
0
22
200
1.12
0.13
2.7
2.7
1.0
1.1
e6/l
0.10
11
102
8
78
1.03
0.07
2.0
1.7
—
—
—
0
0
22
210
1.06
0.04
1.7
1.4
—
—
—
0
0
110
1105
0.98
0.00
21.7
14.1
38.1
39.5
%
0.64
74
800
17
168
1.01
0.00
2.5
2.9
0.6
0.7
ug/l
0.30
11
114
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
55.8
—
0
6
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
0.3
—
0
5
0
9
0.00
0.00
0.0
1.0
—
5.4
—
0
9
0
6
0.00
0.00
0.0
1.5
—
218.7
—
0
6
0
6
0.00
0.00
0.0
3.0
—
1158.2
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
18.5
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
4.5
7.4
23.3
25.2
mmol/l
—
8
73
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
11.2
—
0
7
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_APOCRINESWEAT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_APOCRINESWEAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_APOCRINESWEAT – Apocrine sweat disorders, other sweat gland disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data