Apocrine sweat disorders, other sweat gland disorders

L12_APOCRINESWEAT

sweat gland disease: disorders or sweat glands

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L75 Hospital discharge: ICD-9 — 7058B\|7058X\|7059 Hospital discharge: ICD-8 — 705 Hospital discharge: excluded ICD-8 — 705[0-1] Cause of death: ICD-10 — L75 Cause of death: ICD-9 — 7058B\|7058X\|7059 Cause of death: ICD-8 — 705 Cause of death: excluded ICD-8 — 705[0-1] 2 out of 7 registries used, show all original rules.	149
4. Check minimum number of events None	149
5. Include endpoints None	149
6. Filter based on genotype QC (FinnGen only)	147

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L60-L75
Name in latin: Morbositates glandularum sudoriferarum apocrinarum

NAME	L12_APOCRINESWEAT
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L75
HD_ICD_9	7058B\|7058X\|7059
HD_ICD_8	705
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	705[0-1]
COD_MAINONLY
COD_ICD_10	L75
COD_ICD_9	7058B\|7058X\|7059
COD_ICD_8	705
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	705[0-1]
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Apocrine sweat disorders, other sweat gland disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1190	653	525
Only index persons	958	562	396
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.01
Only index persons	0.02	0.02	0.02
Median age at first event (years)
Whole population	34.11	34.20	33.83
Only index persons	32.47	32.89	31.89

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	147	99	48
Unadjusted period prevalence (%)	0.03	0.04	0.02
Median age at first event (years)	33.51	32.94	34.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
149: Matched controls
1490

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

70591

ICD-8 Finland

Diseases of sweat glands, Hidrosadenitis

+∞

49.8

L73.2

ICD-10 Finland

Hidradenitis suppurativa

85.4

25.8

70590

ICD-8 Finland

Diseases of sweat glands, Hidrosis

+∞

22.5

L75.9

ICD-10 Finland

Apocrine sweat disorder, unspecified

+∞

15.9

L75.8

ICD-10 Finland

Other apocrine sweat disorders

+∞

14.8

7058X

ICD-9 Finland

Disorders of sweat glands, Other specified disorders of sweat glands[MUU HIKIRAUHASSAIRAUS]

+∞

12.7

QBE05

NOMESCO Finland

Excision of sweat glands or sweat gland bearing skin from trunk

+∞

10.5

70599

ICD-8 Finland

Diseases of sweat glands, Other

+∞

10.5

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

5.9

10.4

7058C

ICD-9 Finland

Disorders of sweat glands, Other specified disorders of sweat glands[HIDRADENITIS SUPPURATIVA]

+∞

9.5

S10

ICPC

Boil/carbuncle

5.3

8.4

L02.2

ICD-10 Finland

Cutaneous abscess, furuncle and carbuncle of trunk

7.7

8.1

L72.1

ICD-10 Finland

Trichilemmal cyst

6.9

7.5

9752

FHL

Surgical treatment of hyperhidrosis

+∞

7.3

J44.8

ICD-10 Finland

Other specified chronic obstructive pulmonary disease

3.8

7.2

J01DA09

ATC

[U] cefadroxil

2.6

7.1

277

J01FF01

ATC

clindamycin; systemic

2.5

6.5

288

9734

FHL

Excision and local plastic or associated free skin grafting

72.8

6.5

J01AA07

ATC

tetracycline; systemic

3.0

6.1

115

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

120

3.51

8.69

2.2

1.6

—

(3042936) Bacteria identified in Isolate by Culture

168

2.42

4.55

2.1

2.0

—

(3019225) pH of Specimen

108

2.58

4.03

4.0

3.9

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

368

2.00

3.93

4.0

2.3

57.19

58.46

u/l

0.09

344

(3022217) INR in Platelet poor plasma by Coagulation assay

564

1.96

3.92

14.2

10.7

1.15

1.20

inr

0.24

157

(3022313) Gas panel - Capillary blood

3.41

3.89

4.0

3.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

501

1.90

3.60

2.4

2.1

72.79

77.23

nmol/l

0.79

438

(3006315) Basophils [#/volume] in Blood

585

1.89

3.58

7.8

5.0

0.05

0.04

e9/l

0.69

502

(3009343) pH of Capillary blood

2.82

3.44

4.1

3.2

—

7.44

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

697

1.89

3.42

5.2

4.4

6.77

6.63

mmol/l

0.27

634

(3013115) Eosinophils [#/volume] in Blood

613

1.85

3.33

8.3

5.1

0.20

0.18

e9/l

0.44

539

(3021960) Folate [Moles/volume] in Serum or Plasma

278

1.95

3.27

1.5

21.73

22.92

nmol/l

0.19

220

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

116

944

2.03

3.24

4.0

3.9

14.99

14.79

pmol/l

0.47

101

850

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

101

788

1.87

3.16

4.0

2.8

67.82

45.65

u/l

1.04

741

(40760892) CBC W Ordered Manual Differential panel - Blood

545

1.81

3.13

9.4

5.5

—

(3001604) Monocytes [#/volume] in Blood

584

1.80

3.09

8.0

5.0

0.61

0.55

e9/l

1.15

502

(3044640) Blood type and Crossmatch panel - Blood

376

1.84

3.08

3.2

2.2

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

116

955

1.97

2.98

10.2

6.6

82.48

77.90

u/l

0.35

106

888

(3019198) Lymphocytes [#/volume] in Blood

599

1.77

2.95

8.0

5.1

2.08

1.92

e9/l

0.59

534

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

281

1.86

2.86

2.8

2.2

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

4.63

2.83

1.3

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

484

1.74

2.78

2.2

1.8

88.34

98.30

pmol/l

0.70

217

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

268

1.85

2.74

2.7

1.9

3.02

3.05

mg/l

0.02

225

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.95

2.72

2.3

2.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.30

2.46

1.8

1.4

—

(3002256) Pathology report gross observation

149

1.99

2.45

1.4

1.2

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.27

2.40

5.6

2.8

63.54

67.13

g/l

0.95

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.96

2.40

2.5

1.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

701

1.67

2.38

10.6

8.6

4.46

4.08

e9/l

0.86

598

(3013707) Erythrocyte sedimentation rate by Westergren method

110

917

1.76

2.38

5.5

4.0

14.97

11.91

mm/h

1.02

832

(3020682) Albumin/Creatinine [Ratio] in Urine

374

1.70

2.36

3.9

3.5

4.61

11.12

mg/mmol

1.19

222

(40768804) Tissue Pathology biopsy report

501

1.66

2.35

2.3

2.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

273

1.75

2.30

2.0

1.7

0.88

0.93

mg/l

0.10

221

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

539

1.61

2.13

6.3

5.3

1.22

mmol/l

0.11

495

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

606

1.60

2.12

8.3

6.1

1.22

mmol/l

0.01

529

(3035637) Corticotropin [Mass/volume] in Plasma

5.13

2.08

1.6

1.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

5.13

2.08

1.0

1.5

13.52

19.88

ug/l

—

(3023368) Bacteria identified in Blood by Culture

298

1.68

2.06

5.3

4.2

—

(3025941) Bacteria identified in Stool by Culture

2.24

2.00

1.1

1.2

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

2.04

1.90

3.0

2.9

91.66

73.09

ng/l

0.34

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

357

1.60

1.89

4.7

3.2

1690.31

1164.27

ng/l

0.65

303

(40768797) Stomach Pathology biopsy report

171

1.78

1.88

1.4

1.2

—

(3009508) Creatinine [Moles/volume] in Urine

367

1.59

1.86

3.1

2.8

7.07

7.58

mmol/l

0.35

297

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

3.63

1.85

1.0

1.2

—

(3013512) EKG study

359

1.59

1.84

6.7

3.9

—

(21494890) Protein electrophoresis panel - 24 hour Urine

4.27

1.84

1.2

1.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

824

1.55

1.75

5.8

4.4

—

(40760888) Immunoglobulin light chains.free panel - Serum

3.01

1.74

16.1

6.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

567

1.52

1.74

3.3

2.5

—

(3022145) Colonoscopy Study observation

144

1.79

1.70

1.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.17

1.65

3.4

1.6

—

(3026782) Osmolality of Urine

228

1.64

1.63

4.1

3.2

538.07

526.34

mosm/kgh2o

0.08

194

(3012516) Albumin [Mass/volume] in Urine

350

1.55

1.63

3.0

21.48

460.00

mg/l

0.98

221

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

163

1.72

1.60

4.5

4.2

31.35

33.21

0.31

102

(3002179) Metamyelocytes/100 leukocytes in Blood

1.93

1.59

6.5

4.7

0.36

0.42

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

188

1.67

1.58

2.6

1.8

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

239

1.61

1.57

1.8

373.50

462.77

pmol/l

1.67

197

(3017143) Hepatitis C virus Ab [Presence] in Serum

109

1.85

1.55

1.3

1.4

—

(3044927) Protein electrophoresis panel - Urine

3.41

1.53

1.2

1.1

—

(3024928) Oxygen saturation in Venous blood

2.93

1.52

4.0

2.5

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

2.45

1.48

1.4

1.3

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

2.80

1.45

3.3

6.4

—

176.80

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.03

1.43

1.2

1.4

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

416

1.47

1.39

3.7

3.1

2.33

2.35

mmol/l

0.55

364

(3017181) Myelocytes/100 leukocytes in Blood

106

1.79

1.37

6.8

4.5

0.63

0.99

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

273

1.53

1.36

1.4

1.2

0.52

1.77

u/ml

0.96

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

126

1147

1.64

1.36

5.9

4.7

1.56

2.95

mu/l

0.73

116

1044

(3048689) Calprotectin [Mass/mass] in Stool

147

1.67

1.33

2.3

1.8

65.06

116.26

ug/g

1.29

115

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.56

1.31

1.0

1.5

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

2.56

1.31

1.7

1.6

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.84

1.29

1.2

1.1

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.94

1.28

1.6

1.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

218

1.53

1.22

1.3

24.91

33.07

iu/ml

0.35

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

110

1.72

1.22

5.6

3.3

—

(36660697) Celiac disease serology panel - Serum

1.81

1.20

1.1

—

(3021440) Promyelocytes/100 leukocytes in Blood

1.77

1.19

7.1

4.8

0.00

0.16

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

485

1.40

1.16

7.3

3.8

24.22

36.50

ng/l

0.69

342

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.40

1.14

1.9

2.9

166.71

178.37

—

(3017732) Neutrophils [#/volume] in Blood

1.80

1.13

3.3

2.4

3.13

7.01

e9/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

127

1172

1.57

1.13

4.5

4.0

1.53

1.30

mmol/l

2.05

114

1066

(3019309) Folate [Moles/volume] in Red Blood Cells

214

1.50

1.11

2.3

1.7

1154.63

1207.36

nmol/l

0.12

160

(3004588) Protein electrophoresis panel - Serum or Plasma

1.83

1.11

7.3

2.4

—

(40761536) Microorganisms panel - Urine sediment

1.78

1.09

5.6

3.9

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.06

1.07

1.9

1.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

2.11

1.04

4.9

6.9

—

(3025159) Blasts/100 leukocytes in Blood

1.70

1.01

7.6

4.8

0.00

0.03

—

(3007164) IgA [Mass/volume] in Serum or Plasma

245

1.45

1.01

3.1

1.3

1.95

2.29

g/l

0.64

134

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

129

1203

1.54

0.99

6.0

4.5

6.07

5.97

mmol/l

0.37

116

1100

(3034770) Mitochondria Ab [Titer] in Serum

2.21

0.99

1.4

1.1

—

(1616796) Gas panel - Central venous blood

2.21

0.99

4.2

2.3

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.85

0.98

1.3

3.1

1.81

1.44

g/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.84

0.97

1.2

1.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

169

1.50

0.95

1.5

1.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

321

1.38

0.94

4.7

3.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

130

1218

1.53

0.93

4.9

4.5

4.60

4.74

mmol/l

0.83

115

1121

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.81

0.93

2.8

2.4

—

(3008037) Lactate [Moles/volume] in Venous blood

2.04

0.88

5.2

3.5

1.75

1.48

mmol/l

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.04

0.88

1.2

1.4

—

(3038515) Glucose [Moles/volume] in Venous blood

2.04

0.88

5.2

3.5

6.82

7.62

mmol/l

—

(1002224) Polysomnography panel

1.82

0.86

1.0

1.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

123

1146

1.42

0.85

7.1

5.7

38.84

39.89

mmol/mol

0.79

111

1062

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

131

1.52

0.83

2.6

1.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

131

1236

1.50

0.82

23.3

13.0

21.84

23.54

mg/l

0.19

113

961

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.74

0.82

2.5

2.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

431

1.32

0.82

3.6

2.8

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.72

0.81

1.0

1.2

617.69

217.11

u/ml

0.34

(3044889) 12 lead EKG panel

874

0.77

0.79

4.5

3.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

150

1.47

0.79

4.9

7.2

—

(3027801) Oxygen [Partial pressure] in Arterial blood

133

1.49

0.78

3.3

7.6

11.98

12.43

kpa

0.14

125

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

133

1.49

0.78

2.6

1.8

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

133

1.49

0.78

3.3

7.6

4.92

5.22

kpa

0.89

125

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

2.12

0.75

1.2

1.5

—

(3013290) Carbon dioxide [Partial pressure] in Blood

2.12

0.75

4.0

2.5

4.56

4.98

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

2.12

0.75

4.0

2.5

8.46

8.76

kpa

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.88

0.74

1.3

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

135

1.47

0.73

1.5

1.6

—

(40761511) CBC panel - Blood by Automated count

136

1299

1.54

0.72

20.2

12.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

448

1.28

0.71

4.9

3.9

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

128

1211

1.40

0.70

4.8

4.5

1.46

1.52

mmol/l

0.79

114

1104

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.88

0.69

1.4

1.6

—

(3016502) Oxygen saturation in Arterial blood

120

1.47

0.68

4.1

7.9

95.46

96.02

0.19

114

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

130

1237

1.40

0.64

5.5

5.0

2.65

2.79

mmol/l

1.02

117

1129

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

211

1.34

0.63

1.4

1.3

3.65

11.05

u/ml

1.15

(3001122) Ferritin [Mass/volume] in Serum or Plasma

513

1.25

0.62

3.2

2.4

100.05

116.12

ug/l

0.46

461

(3045414) Leukocytes [Presence] in Urine

1.60

0.61

1.3

1.9

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.57

0.61

1.2

—

54.50

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

133

1273

1.42

0.60

24.5

15.2

139.88

139.82

mmol/l

0.10

128

1238

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.60

0.0

1.7

—

(3029937) Albumin [Presence] in Urine by Test strip

306

1.28

0.58

4.0

3.7

0.00

estimate

-0.00

101

(3023103) Potassium [Moles/volume] in Serum or Plasma

133

1277

1.39

0.55

24.7

15.3

3.99

3.96

mmol/l

0.56

128

1240

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.48

0.54

4.0

6.0

22.12

25.28

mmol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.43

0.52

1.1

1.3

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

172

1.33

0.52

1.8

30.90

29.13

0.61

165

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

110

0.62

0.50

1.3

1.4

—

(3049717) Cytology report of Urine Cyto stain

1.55

0.49

3.9

2.8

—

(3020891) Body temperature

1.48

0.47

2.0

3.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

130

1.35

0.46

2.0

1.6

—

(40761535) Cells panel - Urine sediment

0.62

0.43

2.2

3.0

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

123

1178

1.25

0.43

22.7

12.5

79.17

80.44

ml/min/173m2

0.25

105

939

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

1.63

0.43

3.4

2.5

0.00

g/l

—

(3002582) Erythrocytes [#/volume] in Urine

365

1.21

0.43

4.0

3.0

40.56

35.83

e6/l

0.11

267

(3019832) Treponema pallidum Ab [Presence] in Serum

1.46

0.43

1.4

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

1.58

0.42

1.6

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

134

1297

1.33

0.42

25.3

15.5

85.07

74.65

umol/l

0.70

134

1297

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

187

1.27

0.42

3.0

2.9

4.74

3.04

e6/l

0.26

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.41

0.0

1.1

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.1

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

582

1.17

0.40

4.5

3.8

0.00

estimate

-0.00

107

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.44

0.39

1.0

1.1

—

17.18

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.39

0.0

1.7

—

6.31

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.42

0.38

2.5

3.0

4.67

4.52

pmol/l

—

(3009261) Glucose [Presence] in Urine by Test strip

595

1.16

0.37

4.4

3.8

0.00

estimate

-0.00

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

219

1.23

0.36

4.3

3.2

24.15

73.56

ng/l

1.12

176

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.41

0.35

2.2

1.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

589

1.15

0.33

6.6

5.4

0.00

estimate

-0.00

102

(3021589) Normoblasts [#/volume] in Blood

530

1.15

0.33

12.6

8.9

0.00

0.01

e9/l

0.56

422

(3026008) Bacteria identified in Urine by Culture

375

1.17

0.32

4.6

3.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.36

0.31

1.8

1.7

—

(3030467) Casts [#/volume] in Urine by Automated count

338

1.17

0.30

3.6

2.9

1.16

0.44

e6/l

0.60

237

(4035726) Immunohistochemistry procedure

108

0.73

0.30

2.4

1.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.24

0.29

6.4

3.5

51.91

47.85

—

(3000330) Specific gravity of Urine by Test strip

1.26

0.28

4.9

5.0

—

(3019060) Gas panel - Arterial blood

1.32

0.27

1.8

4.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

243

0.84

0.25

3.5

4.1

17.18

21.59

0.78

122

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

742

0.89

0.25

3.2

3.0

—

(40758558) Short blood count panel - Blood

305

1.15

0.24

8.6

6.6

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

134

1311

1.22

0.24

14.6

9.8

26.26

24.66

u/l

0.68

127

1262

(1761868) Lipid panel - Serum or Plasma

442

1.13

0.24

3.0

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.29

0.23

1.0

2.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

103

0.76

0.22

2.3

1.7

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

1.9

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.21

0.0

1.0

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.0

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.20

0.0

1.1

—

(40768443) Skin Pathology biopsy report

1.16

0.19

1.3

1.2

—

(3000492) Spirometry study

100

1.22

0.18

1.3

1.5

—

(3003694) ABO and Rh group [Type] in Blood

319

0.89

0.18

1.2

1.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.15

0.18

1.1

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.75

0.17

2.0

1.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

275

0.89

0.16

3.0

3.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

199

1.12

0.14

2.7

0.98

1.14

e6/l

0.10

102

(4200892) Spirometry reversibility

1.19

0.12

1.4

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

212

1.10

0.11

1.7

1.4

—

(3000494) Fungus identified in Specimen by Culture

144

1.12

0.11

1.3

1.4

—

(3009542) Hematocrit [Volume Fraction] of Blood

138

1365

1.15

0.10

31.4

19.2

39.62

39.98

0.23

131

1282

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

203

1.10

0.10

1.4

1.5

—

(3018418) pH of Serum or Plasma

372

1.07

0.09

7.1

3.5

7.38

7.40

—

(36304419) Bacteria [Presence] in Urine

323

1.07

0.08

3.6

2.9

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.12

0.08

5.1

2.9

26.36

25.34

mmol/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.08

0.08

7.3

8.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.09

0.07

2.1

1.8

—

(3018095) Leukocytes [#/volume] in Urine

426

1.05

0.05

4.2

3.6

65.47

49.69

e6/l

0.12

285

(3019150) Specific gravity of Urine by Refractometry

262

1.04

0.02

3.7

3.6

1.02

kg/l

—

(3000991) Gas panel - Venous blood

1.08

0.02

9.1

7.5

—

(3015736) pH of Urine

482

1.02

0.01

4.2

3.6

5.50

5.80

—

(21494755) Public health laboratory ask at order entry panel

101

0.99

0.00

1.0

1.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

167

1.02

0.00

2.5

2.8

0.63

0.73

ug/l

0.33

113

(3008152) Bicarbonate [Moles/volume] in Arterial blood

1.01

0.00

4.5

7.4

23.27

25.20

mmol/l

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

10.59

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.96

-0.00

2.0

1.5

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

1158.17

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

45.28

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.94

-0.00

3.0

1.7

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

89.33

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

3.3

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

5.37

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

166.65

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3022621) pH of Urine by Test strip

0.93

-0.00

3.9

2.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.87

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.2

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

1.4

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.0

—

2.97

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.1

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.2

—

0.75

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.4

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

2.7

—

18.47

—

(3035880) pH of Pleural fluid

0.00

-0.00

0.0

1.4

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

218.67

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.33

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

1.63

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

4.4

—

(3015183) Erythrocyte sedimentation rate

0.00

-0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

55.83

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.4

—

32.94

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

24.00

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

9.28

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

-0.00

0.0

1.2

—

(3039429) Cortisol [Moles/volume] in Saliva (oral fluid)

0.00

-0.00

0.0

3.0

—

32.95

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_APOCRINESWEAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_APOCRINESWEAT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_APOCRINESWEAT – Apocrine sweat disorders, other sweat gland disorders

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Apocrine sweat disorders, other sweat gland disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints