This is a non-core endpoint: only basic statistics are computed.
Benign neoplasm: Brain, unspecified
CD2_BENIGN_BRAIN_NOS_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum cerebri non specificatum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Brain, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Brain, unspecified
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 219 | 137 | 82 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 41.78 | 41.18 | 42.78 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 203
- Matched controls
- 2028
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
+∞
104.4
91
*
22500
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
72.3
65
*
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
57.0
52
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
15.1
39.8
70
68
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
89.8
34.1
37
5
2152
FHL
Extraction, big brain
395.5
34.0
33
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
17.1
33.1
54
42
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
52.5
29.8
35
8
H02AB02
ATC
dexamethasone; systemic
90.6
28.7
31
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
35.5
25.9
33
11
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
64.4
20.4
23
*
N03AF01
ATC
carbamazepine; oral, rectal
10.6
20.1
40
46
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
208.4
18.9
19
*
N03AF02
ATC
oxcarbazepine; oral
17.8
18.1
28
18
130
Kela drug reimbursment
Malignant tumour
+∞
18.0
17
*
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
+∞
16.9
16
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
18.3
15.2
23
14
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
61.4
15.0
17
*
E23.00
ICD-10 Finland
Panhypopituitarism
86.5
14.8
16
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
57.5
14.0
16
*
N03AB02
ATC
phenytoin; systemic
17.8
13.8
21
13
D33.30
ICD-10 Finland
Acoustic neuroma
80.7
13.8
15
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
20.0
13.7
20
11
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
16.6
13.4
21
14
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
+∞
12.6
12
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
11.6
12.6
23
22
N03AX14
ATC
levetiracetam; systemic
19.6
12.3
18
10
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
24.6
11.8
16
7
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
11.7
38
87
22520
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
+∞
11.6
11
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.5
11.1
21
22
H02AB09
ATC
hydrocortisone; systemic
14.0
10.9
18
14
XCK00
NOMESCO Finland
Perimetry
5.6
10.6
31
63
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
115.7
10.5
11
*
23810
ICD-8 Finland
Neoplasm of unspecified nature of eye, brain and other parts of nervous system, Brain
+∞
10.5
10
*
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
+∞
9.4
9
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
9.4
9
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
52.3
8.8
10
*
WF002
NOMESCO Finland
Radical radiotherapy
93.7
8.5
9
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
8.4
8
*
2151
FHL
Resection, big brain
+∞
8.4
8
*
H53.4
ICD-10 Finland
Visual field defects
8.0
7.9
17
23
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
46.8
7.8
9
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
83.0
7.5
8
*
G93.0
ICD-10 Finland
Cerebral cysts
83.0
7.5
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
7.3
28
76
WF099
NOMESCO Finland
Other radiotherapy
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
7.3
7
*
D33.02
ICD-10 Finland
Another benign medial tumor of the cerebrum
+∞
7.3
7
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
7.3
7
*
A03FA01
ATC
metoclopramide; systemic, rectal
3.3
7.0
38
134
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
6.8
53
239
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
17.4
6.8
10
6
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
41.5
6.8
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
6.8
45
185
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
9.2
6.7
13
15
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
14.9
6.5
10
7
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
14.9
6.5
10
7
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
72.0
6.5
7
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
72.0
6.5
7
*
AA1AD
NOMESCO Finland
CT of head and brain
2.5
6.4
59
290
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.5
6.3
29
93
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
6.3
6
*
L01AX03
ATC
temozolomide; systemic
+∞
6.3
6
*
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
102
Kela drug reimbursment
Diabetes insipidus
+∞
6.3
6
*
H47.2
ICD-10 Finland
Optic atrophy
27.6
6.3
8
*
R51.80
ICD-10 Finland
Headache
2.7
6.1
42
177
G51.0
ICD-10 Finland
Bell palsy
10.5
6.1
11
11
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
6.0
33
118
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
15
7.67
7.62
1.5
1.5
—
—
—
0
0
115
756
2.10
6.72
7.0
6.0
1.2
1.2
mmol/l
0.00
103
652
104
684
1.99
5.83
6.2
5.5
1.2
1.2
mmol/l
0.26
99
613
133
970
1.95
5.34
5.2
4.5
6.5
6.7
mmol/l
0.45
128
893
35
158
2.45
5.02
8.5
9.3
2.1
1.3
mmol/l
0.84
27
128
98
702
1.72
3.71
3.6
3.7
—
—
—
0
0
22
92
2.55
3.70
4.9
8.1
1.3
1.5
%
0.61
22
92
20
83
2.55
3.42
4.9
6.1
24.1
24.6
mmol/l
0.33
20
83
21
91
2.45
3.29
5.1
8.1
0.7
0.7
%
0.02
21
91
6
7
8.77
3.28
1.0
1.7
—
—
—
0
0
40
242
1.80
2.65
1.7
1.8
—
—
—
0
0
9
25
3.71
2.60
1.4
1.6
—
—
—
0
0
30
169
1.90
2.48
1.7
1.8
—
—
—
0
0
53
356
1.64
2.42
2.1
2.0
—
—
—
0
0
6
12
5.11
2.42
1.3
1.4
2.3
1.9
mmol/l
—
6
12
23
121
2.01
2.31
2.3
1.8
65.0
66.8
ml/min/173m2
—
10
46
7
18
3.98
2.27
1.1
1.3
—
—
—
0
0
47
311
1.65
2.27
1.8
1.7
1439.3
1184.4
nmol/l
0.84
38
241
8
25
3.28
2.11
1.1
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
10
5.09
2.08
1.4
1.3
—
—
—
0
0
8
187
0.41
2.05
1.9
1.7
—
—
—
0
0
8
26
3.15
2.03
1.1
1.2
—
—
—
0
0
7
21
3.41
1.98
1.1
1.1
—
—
—
0
0
21
115
1.91
1.90
3.7
3.6
79.0
81.0
ng/l
0.07
21
100
28
172
1.72
1.78
1.7
1.8
—
—
—
0
0
10
208
0.46
1.67
1.9
1.9
—
—
—
0
0
111
928
1.40
1.66
9.3
6.8
4.4
4.1
e9/l
0.46
98
794
34
225
1.61
1.64
3.0
3.7
0.8
0.8
mmol/l
0.41
34
207
16
84
1.98
1.64
2.4
4.1
0.9
1.6
mmol/l
—
6
62
10
43
2.39
1.63
1.0
1.2
—
—
—
0
0
5
15
3.39
1.53
1.0
1.5
—
—
—
0
0
58
438
1.44
1.53
5.7
3.8
0.0
0.0
estimate
0.00
11
144
85
695
1.36
1.40
3.1
2.3
78.3
76.0
nmol/l
0.29
80
610
150
1341
1.38
1.38
5.4
3.9
14.8
14.7
pmol/l
0.30
138
1213
53
401
1.42
1.38
5.5
3.7
1.0
1.0
kg/l
0.05
13
52
185
1716
1.50
1.37
16.8
12.2
25.3
20.8
mg/l
0.86
153
1295
9
42
2.19
1.35
1.2
1.4
—
—
—
0
0
8
34
2.40
1.30
1.6
3.3
—
—
—
0
0
5
18
2.82
1.29
1.6
1.4
—
—
—
0
0
6
25
2.44
1.25
1.5
1.2
—
—
—
0
0
80
658
1.34
1.25
3.6
3.6
20.3
39.8
ng/l
1.99
60
446
5
19
2.67
1.22
1.0
1.3
—
—
—
0
0
66
530
1.35
1.20
3.5
2.3
56.3
55.1
u/l
0.12
60
491
189
1780
1.45
1.09
20.2
14.1
139.3
139.8
mmol/l
1.39
184
1730
51
400
1.36
1.07
1.8
2.1
3.3
3.0
mg/l
0.25
41
342
45
349
1.36
1.02
1.7
1.7
462.4
453.5
pmol/l
0.09
34
295
5
23
2.20
0.98
1.2
1.1
—
—
—
0
0
189
1789
1.41
0.96
19.9
14.2
4.0
4.0
mmol/l
0.34
184
1737
29
211
1.43
0.94
5.1
4.6
34.0
32.1
%
0.40
23
135
35
451
0.73
0.90
1.9
2.4
331.0
5856.4
umol/l
1.76
29
393
25
179
1.45
0.89
4.5
5.4
1.0
1.0
mmol/l
0.00
25
156
18
121
1.53
0.86
2.8
2.8
4.1
4.6
kpa
0.87
18
116
69
586
1.26
0.81
3.5
2.9
—
—
—
0
0
5
25
2.02
0.73
1.0
1.6
—
—
—
0
0
137
1264
1.22
0.72
8.2
5.5
76.7
75.6
u/l
0.12
131
1168
95
849
1.21
0.68
4.9
3.5
0.0
0.0
estimate
0.00
13
149
13
86
1.54
0.67
1.9
1.7
—
—
—
0
0
5
29
1.74
0.64
1.0
1.6
—
—
—
0
0
77
679
1.21
0.63
5.1
3.5
—
—
—
0
0
28
219
1.32
0.62
2.1
2.3
2.2
2.3
g/l
0.94
28
207
57
489
1.22
0.61
2.6
3.0
1093.3
1436.6
ng/l
0.48
50
397
6
35
1.73
0.58
3.3
1.7
134.3
240.1
pmol/l
—
6
30
11
160
0.67
0.58
1.3
1.8
—
—
—
0
0
27
336
0.78
0.56
1.3
1.3
74.1
40.3
iu/ml
—
10
113
26
205
1.30
0.55
11.4
6.8
—
—
—
0
0
94
855
1.17
0.53
6.1
4.8
0.0
0.0
estimate
0.00
13
143
9
63
1.45
0.53
1.4
1.7
—
—
—
0
0
27
332
0.79
0.51
1.4
1.3
16.4
14.3
u/ml
0.06
12
137
95
867
1.17
0.51
4.9
3.5
0.0
0.0
estimate
0.00
13
146
33
274
1.24
0.48
3.1
2.5
0.3
1.2
e6/l
3.43
16
148
7
47
1.51
0.48
1.0
1.1
—
—
—
0
0
166
1727
0.84
0.48
4.8
4.4
1.5
1.5
mmol/l
0.01
159
1602
167
1736
0.84
0.47
4.7
4.4
4.7
4.7
mmol/l
0.17
157
1620
171
1772
0.84
0.45
5.1
4.9
2.8
2.8
mmol/l
0.01
158
1645
13
95
1.39
0.45
2.0
1.5
—
—
—
0
0
8
56
1.44
0.43
1.3
1.4
—
—
—
0
0
5
33
1.53
0.41
2.6
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
8
60
1.35
0.40
1.5
1.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
161
1670
0.86
0.39
4.3
4.0
1.3
1.3
mmol/l
0.42
154
1536
5
36
1.40
0.38
1.0
1.2
—
—
—
0
0
5
78
0.63
0.36
2.4
1.9
5.0
3.6
mg/l
—
5
63
169
1636
1.14
0.33
14.3
10.4
84.4
81.4
ml/min/173m2
0.99
142
1302
7
99
0.70
0.31
1.4
2.0
—
—
—
0
0
123
1288
0.90
0.31
4.9
4.2
12.0
11.6
mm/h
0.13
117
1179
8
62
1.30
0.28
2.8
1.6
—
—
—
0
0
41
369
1.14
0.27
1.7
1.8
1.3
1.0
mg/l
0.29
25
284
5
72
0.69
0.26
1.6
1.5
—
—
—
0
0
5
74
0.67
0.26
3.4
2.0
—
—
—
0
0
6
83
0.72
0.24
1.3
1.9
—
—
—
0
0
50
459
1.12
0.24
3.8
2.7
0.4
0.3
e6/l
0.10
38
328
29
257
1.15
0.23
3.2
2.7
1.9
3.5
e6/l
0.57
12
131
5
40
1.26
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
9.4
—
0
10
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
35
320
1.11
0.18
1.2
1.5
—
—
—
0
0
166
1694
0.92
0.18
4.8
4.5
5.7
6.0
mmol/l
2.10
156
1541
7
63
1.11
0.17
1.9
1.7
—
—
—
0
0
11
92
1.21
0.16
1.1
1.4
—
—
—
0
0
39
417
0.92
0.14
1.3
1.3
0.9
1.7
u/ml
0.67
14
109
30
277
1.10
0.13
1.7
1.5
—
—
—
0
0
10
85
1.18
0.12
2.9
2.0
1.5
1.2
%
—
10
85
144
1413
1.06
0.11
18.4
14.8
13.7
13.6
%
0.46
137
1382
5
45
1.11
0.10
1.6
2.0
—
—
—
0
0
5
45
1.11
0.10
1.2
1.3
—
—
—
0
0
156
1582
0.95
0.09
17.1
13.4
39.7
40.7
%
0.77
103
1190
13
144
0.90
0.08
2.7
3.9
71.5
210.6
ng/l
2.95
13
130
6
58
1.04
0.08
1.5
1.3
—
—
—
0
0
78
761
1.04
0.07
2.7
2.6
125.7
94.3
ug/l
1.04
70
704
27
258
1.05
0.05
3.4
2.4
0.8
0.7
ug/l
0.01
21
149
47
457
1.04
0.04
1.7
1.7
1.9
1.4
mmol/l
1.68
42
390
37
358
1.04
0.04
4.6
3.4
22.4
24.3
%
0.36
19
148
186
1849
1.04
0.04
11.8
8.8
26.0
25.9
u/l
0.03
178
1783
10
108
0.92
0.03
1.0
1.0
—
—
—
0
0
36
352
1.03
0.02
3.0
4.1
17.0
220.7
ng/l
1.58
29
269
163
1622
1.02
0.01
5.7
4.7
1.6
1.9
mu/l
2.57
148
1473
14
146
0.96
0.00
2.4
2.9
—
—
—
0
0
70
699
1.00
0.00
2.3
2.0
95.3
97.0
pmol/l
0.12
42
356
162
1617
1.01
0.00
5.7
5.9
39.5
39.9
mmol/mol
0.23
151
1518
110
1103
0.99
0.00
2.6
3.1
—
—
—
0
0
116
1155
1.01
0.00
5.3
3.1
58.7
44.4
u/l
1.14
110
1080
5
56
0.89
0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
14.8
—
0
5
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
3.2
—
102.4
—
0
5
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.5
—
91.3
—
0
6
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
9
99
0.91
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
1553.1
—
0
7
5
51
0.98
0.00
2.0
1.7
—
0.1
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_NOS_EXALLC – Benign neoplasm: Brain, unspecified
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).