Neuroendocrine tumor and carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

C3_PANCREAS_NEUROENDOCRINE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C25
  • Cancer registry: Morphology ICD-O-3 8240|8246|8249
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

199

4. Check minimum number of events

None

199

5. Include endpoints

None

199

6. Filter based on genotype QC (FinnGen only)

199

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Neuroendocrine tumor and carcinoma of pancreas, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 199 94 105
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 61.51 59.71 63.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
179
Matched controls
1790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
200.6
114.4
110
14
130
Kela drug reimbursment
Malignant tumour
+∞
114.1
97
*
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
+∞
82.9
73
*
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
+∞
62.2
56
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
54.4
54.5
64
18
A09AA02
ATC
multienzymes (lipase, protease etc.)
87.0
54.5
59
10
H01CB03
ATC
lanreotide; parenteral
+∞
52.8
48
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
51.6
47
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
51.6
47
*
JLC10
NOMESCO Finland
Distal pancreatectomy
+∞
49.3
45
*
L01BC06
ATC
capecitabine; oral
+∞
49.3
45
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
137.4
48.7
50
5
8249/3-C25.9
ICD-O-3
Neuroendocrine tumor, grade 2 of pancreas, NOS
+∞
48.1
44
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
48.1
44
*
L01AX03
ATC
temozolomide; systemic
+∞
45.8
42
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
43.5
40
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
41.3
38
*
H01CB02
ATC
octreotide; parenteral
+∞
39.0
36
*
A03FA01
ATC
metoclopramide; systemic, rectal
11.0
36.5
79
120
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
35.6
33
*
JN4BD
NOMESCO Finland
Extensive body CT
17.3
34.7
57
47
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
+∞
34.5
32
*
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
405.7
34.1
33
*
JN4CD
NOMESCO Finland
Very extensive body CT
49.3
32.8
39
10
JN3BD
NOMESCO Finland
Extensive abdominal CT
11.4
32.7
67
89
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
32.3
30
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
374.8
31.9
31
*
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
193.4
31.8
32
*
D76
ICPC
Malignant neoplasm pancreas
+∞
31.2
29
*
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
186.1
30.7
31
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
35.1
30.5
39
14
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
27.6
30.0
41
19
JN4AD
NOMESCO Finland
Body CT examination
19.7
28.7
44
29
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
25.6
24
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
288.6
25.4
25
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
57.2
25.1
29
6
JN3AD
NOMESCO Finland
Abdominal CT examination
11.5
24.6
48
55
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
24.5
23
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
24.5
23
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
39.6
24.2
30
9
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.7
22.8
49
67
TPH07
NOMESCO Finland
Cathetrisation of artery
8.7
22.5
52
80
JMA10
NOMESCO Finland
Transabdominal total splenectomy
+∞
22.4
21
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
11.9
22.1
42
45
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
14.3
22.0
38
33
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
+∞
21.3
20
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
22.8
20.3
29
15
WX408
NOMESCO Finland
General anesthesy, balanced
4.9
19.9
81
256
WZC30
NOMESCO Finland
Teaching
7.2
19.8
52
96
N02AA05
ATC
oxycodone; systemic
8.1
19.7
47
75
B01AB05
ATC
enoxaparin; parenteral
4.6
19.2
88
311
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
30.5
18.4
24
9
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
+∞
18.0
17
*
158
Kela drug reimbursment
Everolimus
+∞
18.0
17
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
18.0
17
*
197
Kela drug reimbursment
Sunitinib
+∞
18.0
17
*
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
198.9
17.9
18
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
70.4
17.1
19
*
H02AB02
ATC
dexamethasone; systemic
31.1
17.0
22
8
A04AA01
ATC
ondansetron; systemic, rectal
16.7
16.4
26
18
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.2
16.1
79
285
JLC00
NOMESCO Finland
Excision of lesion of pancreas
+∞
15.9
15
*
8249/3-C25.2
ICD-O-3
Neuroendocrine tumor, grade 2 of tail of pancreas
+∞
15.9
15
*
Z51.5
ICD-10 Finland
Palliative care
23.5
15.1
21
10
XX3DW
NOMESCO Finland
Time consuming IT work
9.0
15.0
32
42
8246/3-C25.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of pancreas, NOS
+∞
14.8
14
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
14.8
14
*
C25.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of pancreas
+∞
14.8
14
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
162.7
14.7
15
*
C25.1
ICD-10 Finland
Malignant neoplasm: Body of pancreas
+∞
13.7
13
*
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
+∞
13.7
13
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
151.0
13.6
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
13.5
47
119
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
13.1
105
539
L01XE10
ATC
[U] everolimus; oral
+∞
12.6
12
*
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
+∞
12.6
12
*
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
+∞
12.6
12
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
139.4
12.6
13
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
16.2
12.1
19
13
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
50.3
12.1
14
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
50.3
12.1
14
*
JAH01
NOMESCO Finland
Laparoscopy
11.2
11.9
22
22
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
32.5
11.8
15
5
340
Kela drug reimbursment
Everolimus
+∞
11.6
11
*
8240/3-C25.2
ICD-O-3
Neuroendocrine tumor, NOS, of tail of pancreas
+∞
11.6
11
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
127.9
11.6
12
*
JKA20
NOMESCO Finland
Cholecystectomy
14.0
11.4
19
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
10.7
76
341
JAH00
NOMESCO Finland
Laparotomy
13.2
10.6
18
15
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
17.4
10.6
16
10
L01XE04
ATC
[U] sunitinib; oral
+∞
10.5
10
*
T73
ICPC
Neoplasm endocrine other/unspecified
+∞
10.5
10
*
E16.10
ICD-10 Finland
Hyperinsulinism
+∞
10.5
10
*
A79
ICPC
Malignancy NOS
+∞
10.5
10
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
34.8
10.5
13
*
WX402
NOMESCO Finland
General anaesthesia
4.2
10.2
41
118
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.7
10.0
47
156
B01AB10
ATC
tinzaparin; parenteral
7.2
9.6
23
36
UJK02
NOMESCO Finland
ERCP
13.4
9.6
16
13
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
31.9
9.5
12
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
9.5
9
*
103
Kela drug reimbursment
Diabetes, insulin-treated
2.8
9.3
74
355
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
9.2
81
411
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
38.8
9.1
11
*
A10AE04
ATC
insulin glargine; parenteral
4.1
8.9
35
99
SPAT1262
SPAT
Handing over of treatment supplies
3.2
8.8
52
203
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
12.5
8.7
15
13
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
17.4
8.7
13
8
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
17.4
8.7
13
8
A11CC03
ATC
alfacalcidol; systemic
13.7
8.5
14
11
322
Kela drug reimbursment
Sunitinib
+∞
8.4
8
*
8249/3-C25.0
ICD-O-3
Neuroendocrine tumor, grade 2 of head of pancreas
+∞
8.4
8
*
JN4DD
NOMESCO Finland
Scout CT scan of torso
+∞
8.4
8
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.8
8.4
28
67
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
8.3
69
336
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
8.2
46
173
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
35.1
8.2
10
*
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
13.9
8.0
13
10
E21.0
ICD-10 Finland
Primary hyperparathyroidism
12.6
7.7
13
11
106
Kela drug reimbursment
Hypoparathyroidism
83.4
7.5
8
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
83.4
7.5
8
*
T90
ICPC
Diabetes non-insulin dependent
2.6
7.3
64
315
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
7.3
7
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
7.3
7
*
JLC40
NOMESCO Finland
Total pancreatoduodenectomy
+∞
7.3
7
*
8249/3-C25.1
ICD-O-3
Neuroendocrine tumor, grade 2 of body of pancreas
+∞
7.3
7
*
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
+∞
7.3
7
*
JL2AT
NOMESCO Finland
Cytology of pancreas with ultrasound guidance
+∞
7.3
7
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
31.4
7.2
9
*
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
31.4
7.2
9
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.4
7.1
25
63
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.0
7.0
28
80
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
14.5
7.0
11
8
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
14.5
7.0
11
8
Z31.5
ICD-10 Finland
Genetic counselling
8.8
7.0
14
17
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.6
6.9
59
284
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
41.7
6.8
8
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
41.7
6.8
8
*
J01MA12
ATC
levofloxacin; systemic
2.8
6.8
48
209
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
23.5
6.7
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
6.5
49
221
WF002
NOMESCO Finland
Radical radiotherapy
72.3
6.5
7
*
BBA50
NOMESCO Finland
Total parathyroidectomy
72.3
6.5
7
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
72.3
6.5
7
*
A06AH03
ATC
naloxegol; oral
72.3
6.5
7
*
R4190
NOMESCO Finland
Nutritional therapy
8.7
6.5
13
16
ZXF10
NOMESCO Finland
Interruption caused by technical failure of equipment
+∞
6.3
6
*
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
+∞
6.3
6
*
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
+∞
6.3
6
*
8246/3-C25.2
ICD-O-3
Neuroendocrine carcinoma, NOS, of tail of pancreas
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
6.3
6
*
V03AH01
ATC
diazoxide; systemic
+∞
6.3
6
*
WW500
NOMESCO Finland
Blood transfusion
8.1
6.2
13
17
K83.0
ICD-10 Finland
Cholangitis
13.1
6.2
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
162
9
945.21
194.64
9.8
2.2
45.0
3.7
nmol/l
—
162
9
85
41
35.44
119.53
1.6
1.3
—
—
—
0
0
100
86
22.36
106.75
3.6
1.4
5.2
2.6
ug/l
1.10
81
65
58
12
67.80
102.83
4.4
1.3
27.1
16.9
ug/l
0.80
58
12
70
39
27.15
91.49
2.0
1.2
198.5
320.5
ug/g
2.51
59
22
59
33
24.99
76.31
3.3
1.4
715.9
10.1
u/ml
0.51
54
23
47
41
14.70
47.37
2.2
1.2
0.7
0.9
nmol/l
0.41
47
33
156
636
7.72
37.46
10.5
3.6
34.7
35.8
g/l
2.09
151
591
136
507
6.31
35.54
5.3
2.2
75.3
57.5
u/l
0.47
130
467
149
602
6.87
35.48
11.5
7.8
1.2
1.3
inr
0.42
50
159
23
13
19.87
28.59
2.5
1.5
—
—
—
0
0
146
670
5.43
27.25
11.8
5.2
1.2
1.2
mmol/l
0.74
141
597
152
734
5.53
26.22
14.4
5.7
1.2
1.2
mmol/l
0.59
124
636
111
434
4.52
24.97
8.6
3.4
7.4
7.4
ph
0.06
31
66
137
635
4.72
24.24
5.9
3.5
—
—
—
0
0
58
145
5.23
22.85
3.9
2.0
126.6
31.9
u/l
0.94
53
119
164
911
5.55
21.87
9.2
4.1
7.3
6.7
mmol/l
2.88
159
840
65
186
4.70
21.63
4.7
2.4
8.5
7.1
umol/l
0.21
57
161
94
386
3.72
18.49
6.8
4.0
—
—
—
0
0
100
431
3.65
18.20
3.0
1.9
—
—
—
0
0
102
475
3.35
15.90
10.5
2.1
2.4
2.4
mmol/l
0.20
96
389
44
118
4.50
15.52
6.0
4.6
60.7
84.7
ng/l
1.56
37
102
147
869
3.65
15.16
21.6
6.2
4.2
4.3
e9/l
0.08
138
762
17
18
10.23
14.53
2.3
1.8
689.0
208.3
u/ml
0.29
17
18
79
347
3.12
13.09
16.7
4.7
—
—
—
0
0
43
128
4.01
13.09
1.5
1.1
—
—
—
0
0
99
496
2.98
12.94
8.3
5.2
—
—
—
0
0
53
187
3.50
12.54
2.5
2.4
18.6
23.5
%
1.88
45
160
27
58
5.23
12.30
6.4
3.7
—
—
—
0
0
35
95
4.26
12.01
8.3
4.1
—
—
—
0
0
34
91
4.30
11.88
11.4
6.5
25.3
24.9
mmol/l
0.38
34
86
47
166
3.40
11.00
8.4
6.5
1.8
1.4
mmol/l
0.25
41
131
128
782
2.78
10.84
9.8
5.1
0.0
0.0
e9/l
0.14
114
676
117
688
2.70
10.62
21.4
7.8
0.0
0.0
e9/l
1.14
103
553
127
778
2.75
10.61
9.9
5.1
0.6
0.6
e9/l
1.28
113
670
94
498
2.68
10.51
2.6
1.6
—
—
—
0
0
46
165
3.33
10.47
8.5
6.5
13.7
11.7
kpa
1.31
46
160
46
165
3.33
10.47
8.5
6.5
5.3
5.2
kpa
0.17
46
158
129
803
2.72
10.33
9.9
5.3
0.2
0.2
e9/l
0.39
117
706
128
794
2.72
10.32
10.0
5.1
2.0
1.9
e9/l
0.55
116
695
15
21
7.64
10.28
2.1
1.4
—
—
—
0
0
15
21
7.64
10.28
2.2
1.4
—
—
nmol/l
—
0
0
15
9
17.89
10.04
1.0
1.0
—
—
—
0
0
11
11
10.53
9.63
3.9
1.2
—
—
—
0
0
56
267
2.53
7.37
8.2
2.0
2.5
2.4
mmol/l
2.12
49
224
35
134
2.96
7.01
3.7
3.4
136.8
232.6
ng/l
1.02
28
125
65
342
2.34
6.83
2.7
2.0
3.0
3.0
mg/l
0.03
57
281
87
526
2.16
6.46
3.0
3.2
6.7
7.8
mmol/l
1.72
75
447
79
461
2.18
6.41
3.5
3.0
12.7
86.1
e6/l
2.00
63
350
72
406
2.21
6.35
2.8
2.8
—
—
—
0
0
14
31
4.78
6.08
2.4
2.7
—
—
—
0
0
47
228
2.39
5.85
2.3
1.9
—
—
—
0
0
28
106
2.91
5.69
4.0
3.0
—
—
—
0
0
72
423
2.10
5.61
3.2
2.9
0.4
0.5
e6/l
0.24
57
307
84
537
1.98
5.09
3.7
3.5
80.7
91.3
e6/l
0.08
66
378
140
1083
1.99
4.65
3.9
3.9
—
—
—
0
0
7
5
14.43
4.61
1.6
1.4
29.4
28.2
umol/l
—
7
5
78
500
1.92
4.59
3.1
3.3
41.7
53.8
mg/l
0.28
58
326
82
536
1.90
4.54
3.9
4.1
10.4
7.0
mg/mmol
0.34
56
344
149
1184
2.03
4.50
5.0
3.7
—
—
—
0
0
61
363
1.98
4.44
1.4
1.4
—
—
—
0
0
43
226
2.15
4.36
1.5
1.2
—
—
—
0
0
65
402
1.92
4.20
4.0
3.5
0.0
0.0
estimate
0.00
25
121
20
75
2.85
4.13
13.8
8.1
—
—
—
0
0
58
352
1.91
3.94
1.9
1.7
1.5
1.1
mg/l
0.82
46
272
10
25
4.16
3.74
6.3
2.2
—
—
—
0
0
57
350
1.88
3.71
4.1
4.4
—
—
—
0
0
91
656
1.71
3.40
4.2
3.4
37.7
42.0
ng/l
0.09
72
462
65
429
1.77
3.31
3.8
3.1
—
—
—
0
0
184
1645
2.57
3.26
33.9
11.6
35.0
22.5
mg/l
4.72
170
1242
63
418
1.74
3.13
2.8
3.0
—
—
—
0
0
5
5
10.21
2.99
4.6
2.2
0.6
1.1
ug/l
—
5
5
13
46
2.95
2.98
2.4
1.7
—
—
—
0
0
24
123
2.08
2.58
6.2
7.5
—
—
—
0
0
6
12
5.12
2.42
1.0
1.1
—
—
—
0
0
52
350
1.66
2.39
1.6
1.7
463.1
428.0
pmol/l
0.23
42
289
97
762
1.53
2.30
4.0
3.5
0.0
0.0
estimate
0.00
29
125
97
767
1.52
2.20
5.2
4.8
0.0
0.0
estimate
0.00
28
125
26
146
1.90
2.19
1.2
1.3
—
—
—
0
0
98
780
1.51
2.14
4.0
3.5
0.0
0.0
estimate
0.00
27
120
6
15
4.09
2.05
1.5
2.2
29.2
34.3
pg
—
6
15
19
100
2.00
1.93
3.3
4.9
0.0
0.0
%
—
6
22
86
678
1.47
1.91
2.2
1.9
87.4
94.0
pmol/l
0.71
55
354
29
178
1.74
1.86
1.5
1.4
—
—
—
0
0
23
134
1.81
1.75
3.2
2.9
—
—
—
0
0
7
24
2.98
1.74
2.9
2.8
3.9
4.8
e9/l
—
7
24
7
25
2.86
1.66
3.1
3.6
56.4
57.4
%
—
7
25
64
488
1.46
1.65
5.1
3.8
—
—
—
0
0
139
1222
1.46
1.63
3.5
4.1
13.5
10.7
mm/h
1.04
124
1114
5
14
3.63
1.62
1.2
1.1
—
—
—
0
0
7
26
2.75
1.59
1.0
1.3
—
—
—
0
0
140
1236
1.45
1.57
5.2
3.8
14.5
14.8
pmol/l
0.65
134
1112
19
108
1.84
1.57
3.3
4.7
0.7
0.6
%
—
7
26
5
15
3.39
1.53
1.2
1.4
—
—
—
0
0
5
15
3.39
1.53
1.2
1.4
—
—
—
0
0
5
15
3.39
1.53
1.2
1.4
—
—
—
0
0
5
15
3.39
1.53
1.2
1.4
—
—
—
0
0
7
28
2.55
1.46
1.4
2.3
51.2
61.9
%
—
7
28
6
22
2.78
1.44
5.0
2.5
—
—
—
0
0
43
311
1.49
1.43
1.9
1.7
1186.7
1135.9
nmol/l
0.14
37
234
25
159
1.65
1.43
3.8
3.4
1.8
2.0
mmol/l
0.06
19
121
28
184
1.61
1.41
1.8
1.5
—
—
—
0
0
25
160
1.64
1.40
3.8
3.4
5.7
5.8
kpa
0.27
25
154
28
185
1.60
1.38
2.0
1.6
—
—
—
0
0
7
148
0.45
1.38
1.1
1.5
—
—
—
0
0
18
105
1.79
1.38
6.6
4.2
5.5
5.2
kpa
0.81
18
97
21
129
1.70
1.36
4.1
2.7
4.7
4.3
kpa
0.28
21
122
17
98
1.80
1.36
2.7
5.0
0.3
0.3
%
—
6
19
25
162
1.62
1.34
1.8
1.5
—
—
—
0
0
10
48
2.14
1.30
1.7
1.6
—
—
—
0
0
8
35
2.34
1.28
6.3
2.8
26.2
24.0
mmol/l
—
8
29
25
166
1.58
1.22
4.4
3.5
—
—
—
0
0
17
103
1.71
1.17
3.6
4.8
0.0
0.1
%
—
6
24
17
266
0.61
1.17
1.1
1.2
1.5
9.7
u/ml
—
9
101
5
114
0.42
1.16
2.2
1.5
—
—
—
0
0
43
325
1.41
1.14
3.7
3.7
129.1
359.0
ng/l
0.85
30
261
183
1738
1.66
1.13
34.6
11.2
—
—
—
0
0
165
1538
1.43
1.08
5.6
4.5
2.0
2.7
mu/l
0.44
152
1394
22
149
1.54
1.00
10.9
3.7
—
—
—
0
0
13
78
1.71
0.94
6.5
8.6
25.5
24.9
mmol/l
0.17
13
71
14
86
1.68
0.93
2.9
2.1
0.9
1.3
%
1.03
14
86
13
79
1.69
0.90
1.6
1.2
—
—
—
0
0
8
45
1.81
0.85
1.4
2.7
1.6
1.5
mg/l
—
8
40
13
82
1.63
0.80
3.1
4.0
24.6
24.7
mmol/l
0.01
13
71
52
429
1.29
0.79
2.3
2.4
354.4
9170.4
umol/l
2.26
46
370
8
132
0.59
0.76
1.0
1.4
—
—
—
0
0
160
1511
1.30
0.73
30.2
12.6
38.4
40.4
%
2.08
117
1076
16
109
1.51
0.73
1.0
1.2
—
—
—
0
0
174
1663
1.37
0.73
7.5
4.6
6.8
6.0
mmol/l
6.61
168
1506
15
101
1.52
0.72
2.2
1.3
—
—
—
0
0
44
363
1.27
0.67
4.3
3.7
1.0
1.0
kg/l
2.18
11
56
8
50
1.62
0.62
4.1
3.5
—
—
—
0
0
5
30
1.68
0.62
1.8
2.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.4
—
—
—
0
0
6
35
1.74
0.58
4.7
2.7
—
—
—
0
0
5
87
0.56
0.57
1.2
1.2
115.6
186.7
u/ml
—
5
76
12
82
1.49
0.56
8.7
4.4
—
—
—
0
0
9
60
1.52
0.55
1.8
2.0
—
—
—
0
0
19
144
1.35
0.53
2.4
2.4
5.7
8.2
ug/l
0.34
19
125
13
92
1.44
0.52
1.2
1.5
—
—
—
0
0
23
286
0.78
0.49
1.0
1.3
15.8
34.8
iu/ml
—
7
91
8
117
0.67
0.47
1.0
1.3
—
41.3
—
0
9
7
50
1.41
0.45
2.7
3.3
—
—
—
0
0
56
627
0.85
0.43
3.0
3.1
—
—
—
0
0
12
87
1.40
0.43
3.8
3.5
—
—
—
0
0
5
31
1.63
0.43
1.8
2.2
4.1
4.1
mmol/l
—
5
31
5
31
1.63
0.43
1.8
2.2
104.0
105.4
mmol/l
—
5
31
5
31
1.63
0.43
2.2
2.2
—
—
—
0
0
10
138
0.71
0.42
1.1
1.4
—
—
—
0
0
67
605
1.16
0.42
4.1
3.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
10
71
1.43
0.40
8.6
5.0
24.9
25.1
mmol/l
—
10
65
13
99
1.34
0.36
2.2
2.9
—
—
—
0
0
40
353
1.17
0.33
3.3
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
262.6
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
7.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
70
663
1.09
0.19
3.9
3.7
2.0
1.9
ug/l
0.10
62
602
20
179
1.13
0.15
1.4
1.6
—
—
—
0
0
9
110
0.81
0.13
1.2
1.9
9.9
11.1
g/l
—
9
100
19
210
0.89
0.13
1.2
1.3
288.0
608.9
titre
—
5
54
14
158
0.88
0.12
1.4
1.3
—
—
—
0
0
6
56
1.07
0.08
1.3
1.1
—
—
—
0
0
36
342
1.06
0.08
1.6
1.2
2.7
2.0
u/ml
0.17
13
100
8
93
0.85
0.07
2.1
2.2
—
—
—
0
0
9
100
0.90
0.06
1.3
1.6
—
—
—
0
0
140
1416
0.96
0.06
43.4
15.0
330.6
333.1
g/l
2.20
140
1407
36
374
0.95
0.05
2.5
2.5
0.9
0.8
ug/l
0.33
22
235
168
1690
0.96
0.03
4.8
4.7
4.3
4.6
mmol/l
4.90
162
1570
13
122
1.07
0.03
1.5
1.1
—
—
—
0
0
167
1679
0.97
0.02
4.6
4.6
1.4
1.5
mmol/l
1.82
161
1551
10
94
1.07
0.01
1.0
1.3
0.8
1.1
g/l
—
10
86
22
226
0.97
0.00
2.0
1.7
—
—
—
0
0
30
304
0.98
0.00
1.5
1.3
2.5
2.6
g/l
0.13
18
184
163
1625
1.02
0.00
4.4
4.2
1.4
1.3
mmol/l
0.90
156
1490
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2.5
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
172
1720
1.00
0.00
5.0
5.2
2.5
2.8
mmol/l
4.00
163
1589
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
6.5
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
38.2
—
7.1
—
0
5

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_PANCREAS_NEUROENDOCRINE_EXALLC – Neuroendocrine tumor and carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).