≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback
info icon

Carcinoma in situ of uteri, other/unspecified

Endpoint Browser

CD2_INSITU_CERVIX_UTERI_NOS_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D06.7&, D06.9&
  • Hospital discharge: ICD-9 — 2331
  • Cause of death: ICD-10 — D06.7&, D06.9&
  • Cause of death: ICD-9 — 2331

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 227 227 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 35.79 35.79 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
212
Matched controls
2120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
1404.1
166.6
141
*
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
138.1
117
*
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
109.0
95
*
8326
FHL
Batch conization
118.5
57.4
60
7
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
12.8
34.1
64
69
ULA02
NOMESCO Finland
Kolposcopy
7.1
30.7
89
197
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
7.2
30.6
87
187
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
77.6
29.9
33
5
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
18.0
25.5
40
27
LDA10
NOMESCO Finland
Curettage of cervix uteri
9.4
22.2
48
64
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
5.0
21.2
80
227
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
5.9
17.5
53
114
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
54.9
17.3
20
*
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
+∞
14.8
14
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.7
13
*
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
137.8
12.6
13
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.6
11
*
115
Kela drug reimbursment
Breast cancer
+∞
11.6
11
*
PJA12
NOMESCO Finland
Sentinel node biopsy
115.5
10.5
11
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
31.6
9.5
12
*
HAC20
NOMESCO Finland
Total mastectomy
104.5
9.5
10
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
9.6
8.7
17
19
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
8.4
8
*
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
+∞
8.4
8
*
8076/3-C53.9
ICD-O-3
Squamous cell carcinoma, microinvasive of cervix uteri
+∞
8.4
8
*
L02BA01
ATC
tamoxifen; oral
82.9
7.5
8
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
82.9
7.5
8
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
71.9
6.5
7
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
71.9
6.5
7
*
H02AB02
ATC
dexamethasone; systemic
11.5
6.4
11
10
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
6.3
6
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
459
2.11
6.26
1.8
2.0
—
—
—
0
0
15
38
4.16
5.53
2.3
1.8
—
—
—
0
0
16
43
3.93
5.47
1.9
1.2
—
—
—
0
0
12
36
3.46
3.53
1.2
1.8
—
—
—
0
0
92
702
1.52
2.41
2.1
1.7
—
—
—
0
0
17
85
2.08
1.96
8.2
2.9
—
—
—
0
0
60
435
1.52
1.95
3.2
3.3
—
—
—
0
0
25
146
1.80
1.87
3.1
2.9
—
—
—
0
0
15
75
2.07
1.74
9.7
5.3
—
—
—
0
0
181
1942
0.66
1.60
4.2
4.3
5.9
5.8
mmol/l
0.61
169
1812
13
64
2.09
1.57
1.3
1.4
—
—
—
0
0
13
64
2.09
1.57
1.3
1.4
—
—
—
0
0
13
64
2.09
1.57
1.3
1.4
—
—
—
0
0
13
64
2.09
1.57
1.3
1.4
—
—
—
0
0
16
86
1.93
1.54
1.8
1.9
—
—
—
0
0
5
15
3.38
1.53
1.0
1.0
—
—
—
0
0
0
44
0.00
1.53
0.0
1.1
—
—
—
0
0
27
404
0.62
1.50
1.2
1.3
1.9
2.4
g/l
2.07
18
238
9
40
2.30
1.42
6.3
3.9
—
—
—
0
0
177
1898
0.69
1.41
5.4
5.1
1.7
2.5
mu/l
0.63
169
1780
27
176
1.61
1.39
1.3
1.1
—
—
—
0
0
27
176
1.61
1.39
1.6
1.4
—
—
—
0
0
75
606
1.35
1.31
3.1
3.0
196.0
16.9
ng/l
0.81
34
359
112
963
1.32
1.28
3.1
3.5
6.6
6.5
mmol/l
0.37
106
891
56
706
0.73
1.27
1.9
1.9
91.7
101.4
pmol/l
1.06
30
337
35
478
0.68
1.26
1.3
1.3
2.1
2.3
u/ml
0.04
11
137
12
63
1.96
1.25
4.1
9.0
91.9
94.1
%
0.71
12
63
9
170
0.51
1.24
1.1
1.1
—
—
—
0
0
58
455
1.37
1.21
1.4
1.4
—
—
—
0
0
0
33
0.00
1.17
0.0
1.7
—
—
—
0
0
8
39
2.09
1.16
5.5
3.2
—
—
—
0
0
10
182
0.53
1.16
2.7
1.8
—
—
—
0
0
12
65
1.89
1.16
4.1
8.7
0.8
0.6
%
0.85
12
65
10
181
0.53
1.14
2.5
1.4
—
—
—
0
0
88
743
1.30
1.11
4.1
3.0
—
—
—
0
0
168
1798
0.75
1.09
12.6
11.3
38.7
40.0
%
1.16
134
1392
172
1833
0.75
1.06
5.3
5.1
39.0
38.8
mmol/mol
0.14
161
1732
19
123
1.59
1.03
3.4
3.3
—
—
—
0
0
51
403
1.34
1.02
5.8
5.2
—
—
—
0
0
18
117
1.58
0.97
3.3
3.2
3.0
2.2
mmol/l
0.42
12
96
8
144
0.54
0.97
3.9
3.5
—
—
—
0
0
9
51
1.80
0.95
1.3
1.4
—
—
—
0
0
6
27
2.25
0.94
1.0
1.0
—
0.3
—
0
6
6
27
2.25
0.94
1.0
1.1
—
—
—
0
0
57
464
1.31
0.93
2.2
2.7
7.4
7.4
ph
—
8
73
22
309
0.68
0.92
1.8
1.3
275.6
532.2
titre
—
9
72
6
29
2.10
0.90
1.5
1.7
—
—
—
0
0
13
202
0.62
0.87
1.1
1.2
168.7
125.6
iu/ml
—
7
90
6
112
0.52
0.85
4.3
1.2
67.3
67.7
g/l
—
6
103
11
65
1.73
0.84
4.4
8.7
2.3
1.4
%
1.08
11
65
20
139
1.48
0.82
4.6
5.4
104.5
103.9
mmol/l
0.32
20
133
6
32
1.90
0.82
3.7
2.2
7.7
7.1
mmol/l
—
6
32
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
6
34
1.78
0.77
3.7
2.2
1.4
1.4
mmol/l
—
6
34
7
38
1.87
0.74
5.0
4.2
1.5
1.2
mmol/l
—
7
38
106
953
1.21
0.71
6.8
4.5
0.0
0.0
estimate
0.00
16
166
7
42
1.69
0.69
2.6
2.0
8.0
10.6
u/ml
—
7
35
106
958
1.20
0.66
4.6
3.3
0.0
0.0
estimate
0.80
15
164
20
147
1.40
0.64
5.3
3.0
4.6
4.6
pmol/l
0.18
20
131
6
102
0.58
0.64
1.3
1.1
—
—
—
0
0
142
1322
1.20
0.63
3.2
3.2
—
—
—
0
0
19
254
0.73
0.63
2.1
1.5
—
—
—
0
0
69
602
1.21
0.62
3.5
3.1
9.9
67.8
e6/l
3.05
51
396
37
301
1.27
0.62
3.0
3.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
201
2067
0.76
0.59
13.7
10.8
67.1
68.3
umol/l
0.49
201
2067
45
530
0.81
0.58
5.8
2.8
—
—
—
0
0
9
61
1.49
0.54
1.3
1.4
—
—
—
0
0
9
64
1.42
0.52
1.6
1.4
58.0
53.5
pmol/l
—
9
64
49
564
0.83
0.50
1.5
1.7
1.5
1.4
mmol/l
0.30
41
478
10
67
1.52
0.50
4.0
4.5
—
—
—
0
0
158
1656
0.85
0.50
4.4
4.3
14.8
14.5
pmol/l
0.81
149
1550
7
107
0.64
0.50
1.0
1.4
1.5
1.3
g/l
—
7
98
7
45
1.57
0.49
2.3
2.1
—
—
—
0
0
191
1968
0.81
0.48
12.2
10.9
3.9
3.9
mmol/l
0.41
186
1917
15
111
1.38
0.48
5.3
2.6
—
—
—
0
0
12
164
0.72
0.47
2.4
2.4
—
19.8
—
0
6
191
1964
0.83
0.43
12.1
10.8
139.8
140.0
mmol/l
0.24
186
1915
21
168
1.28
0.42
1.4
1.4
—
—
—
0
0
5
33
1.53
0.41
1.6
3.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
186
1915
0.84
0.41
11.2
9.8
18.6
17.7
mg/l
0.15
146
1426
0
18
0.00
0.40
0.0
3.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
8
61
1.32
0.40
2.6
8.3
24.2
24.9
mmol/l
—
8
61
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
195
1998
0.83
0.39
4.0
4.3
5.0
5.0
mmol/l
0.22
185
1888
9
68
1.34
0.38
4.2
2.0
1.3
1.1
%
—
9
68
5
37
1.36
0.37
4.6
1.7
—
—
—
0
0
5
37
1.36
0.37
1.4
1.4
—
—
—
0
0
140
1465
0.88
0.36
3.8
4.1
11.6
10.9
mm/h
0.29
134
1362
17
135
1.28
0.36
2.2
2.3
1.8
1.6
%
0.32
17
120
9
125
0.71
0.36
2.3
3.4
48.8
76.2
ng/l
—
9
108
55
494
1.15
0.36
3.6
3.4
0.0
0.0
estimate
0.00
16
170
85
914
0.89
0.35
6.6
5.3
2.0
2.0
e9/l
0.15
78
813
6
86
0.69
0.33
3.5
3.5
5.3
5.4
kpa
—
6
79
48
429
1.15
0.33
1.2
1.3
28.6
34.0
iu/ml
0.16
21
145
34
388
0.85
0.33
1.4
1.5
22.3
22.6
nmol/l
0.03
29
328
10
131
0.75
0.31
1.2
2.1
10.9
10.4
g/l
—
10
126
86
802
1.12
0.31
2.7
2.7
—
—
—
0
0
28
241
1.18
0.31
1.7
1.8
—
—
—
0
0
198
2019
0.85
0.30
4.5
4.8
3.0
2.9
mmol/l
0.07
186
1892
60
549
1.13
0.30
3.1
2.7
—
—
—
0
0
19
227
0.82
0.30
1.2
1.3
—
—
—
0
0
20
167
1.22
0.29
1.5
1.2
—
—
—
0
0
100
943
1.11
0.29
4.1
3.2
0.0
0.0
estimate
0.00
14
170
46
508
0.88
0.29
2.7
3.0
17.2
322.1
mg/l
0.87
26
294
51
559
0.89
0.28
5.9
5.6
—
—
—
0
0
103
976
1.10
0.27
10.4
6.8
3.9
4.0
e9/l
0.08
92
852
85
902
0.91
0.26
6.0
5.3
0.0
0.0
e9/l
0.12
76
779
79
840
0.91
0.25
5.8
5.4
30.1
29.9
%
0.08
74
782
125
1301
0.91
0.25
4.7
4.0
—
—
—
0
0
195
1986
0.87
0.25
3.8
4.3
1.6
1.6
mmol/l
0.66
184
1869
21
180
1.18
0.25
1.2
1.3
—
—
—
0
0
6
84
0.71
0.24
3.5
3.5
—
7.4
—
0
14
23
200
1.17
0.23
2.7
2.1
29.0
29.7
s
0.28
23
192
34
306
1.13
0.22
4.5
2.2
489.7
516.0
mosm/kgh2o
0.31
29
263
48
442
1.11
0.22
5.3
3.9
—
—
—
0
0
83
786
1.09
0.22
7.7
7.2
0.0
0.0
e9/l
0.72
72
648
8
101
0.78
0.21
1.0
1.1
—
—
—
0
0
8
103
0.77
0.21
2.5
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
10.1
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
1.6
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
88.2
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
85
894
0.92
0.21
5.8
5.3
0.5
0.5
e9/l
0.53
76
777
52
559
0.91
0.21
2.8
2.1
49.6
57.2
u/l
1.17
46
514
0
13
0.00
0.21
0.0
1.6
—
1.1
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
12
144
0.82
0.20
1.2
1.3
—
38.0
—
0
9
5
67
0.74
0.17
1.8
1.6
212.2
278.9
mu/l
—
5
60
5
70
0.71
0.17
1.0
1.2
—
—
—
0
0
12
141
0.84
0.17
1.3
1.3
—
—
—
0
0
12
141
0.84
0.17
3.1
3.2
—
—
—
0
0
14
162
0.86
0.17
4.4
4.0
1.0
1.0
mmol/l
0.01
14
144
90
937
0.93
0.16
5.8
5.8
0.2
0.2
e9/l
1.13
80
836
60
568
1.08
0.16
10.0
6.3
1.1
1.1
inr
0.11
23
182
6
80
0.74
0.15
1.8
1.6
—
—
—
0
0
22
243
0.90
0.14
1.1
1.4
—
—
—
0
0
24
218
1.11
0.14
1.1
1.4
—
—
—
0
0
51
482
1.07
0.14
3.8
3.0
—
—
—
0
0
56
533
1.07
0.13
4.2
3.7
3.9
7.3
mg/mmol
0.68
34
301
50
474
1.07
0.12
3.3
2.6
11.3
87.8
e6/l
1.52
41
350
13
115
1.14
0.11
1.5
1.2
—
—
—
0
0
57
547
1.06
0.10
2.5
2.9
6.3
7.0
mmol/l
0.46
52
454
5
46
1.09
0.09
1.6
1.2
—
—
—
0
0
6
56
1.07
0.08
2.7
3.8
—
—
—
0
0
46
442
1.05
0.07
3.3
2.6
0.2
0.5
e6/l
2.10
36
323
25
265
0.94
0.07
1.5
1.6
1343.1
1149.7
nmol/l
0.48
20
197
21
197
1.07
0.06
1.4
1.3
—
—
—
0
0
9
104
0.86
0.06
2.2
1.3
—
—
—
0
0
29
304
0.95
0.06
2.1
1.7
—
—
—
0
0
134
1357
0.97
0.05
7.2
5.1
77.5
75.8
u/l
0.27
129
1249
41
424
0.96
0.05
3.5
2.0
1.3
0.9
mg/l
0.50
34
327
21
221
0.95
0.04
2.0
1.8
—
—
—
0
0
10
91
1.10
0.04
4.6
7.8
—
—
—
0
0
189
1901
0.97
0.03
3.5
3.9
1.3
1.2
mmol/l
0.30
174
1778
33
340
0.97
0.03
1.8
2.0
2.5
7.9
e6/l
6.76
27
300
32
312
1.03
0.02
2.5
3.5
51.3
303.4
ng/l
0.63
18
217
53
537
0.98
0.01
2.0
1.9
171.8
121.1
u/l
0.40
53
511
29
284
1.02
0.00
1.1
1.2
—
—
—
0
0
204
2041
1.00
0.00
10.9
9.5
—
—
—
0
0
43
429
1.00
0.00
1.3
1.3
34.8
10.9
u/ml
0.50
14
176
170
1702
1.00
0.00
16.2
13.0
331.6
331.0
g/l
0.37
170
1694
12
117
1.03
0.00
5.8
4.7
—
0.4
—
0
15
44
443
0.99
0.00
2.3
2.5
—
—
—
0
0
16
165
0.97
0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
9.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
13.3
—
0
9
6
69
0.87
0.00
3.8
6.6
24.5
25.4
mmol/l
—
6
69
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
27.7
—
90.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
34.0
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
0.00
1.8
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_CERVIX_UTERI_NOS_EXALLC – Carcinoma in situ of uteri, other/unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).