No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditions
|
- |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ vaginae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of cervix uteri
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of cervix uteri
- In situ neoplasms
- In situ neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5402 | 5402 | - |
| Only index persons | 5151 | 5151 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.15 | - |
| Only index persons | 0.19 | 0.19 | - |
| Median age at first event (years) | |||
| Whole population | - | 36.09 | - |
| Only index persons | - | 35.80 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3866 | 3866 | - |
| Unadjusted period prevalence (%) | 1.32 | 1.32 | - |
| Median age at first event (years) | 35.40 | 35.40 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3487
- Matched controls
- 34870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
25.4
323.0
2461
3005
LDA10
NOMESCO Finland
Curettage of cervix uteri
16.7
323.0
1146
994
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
85.4
323.0
2394
871
ULA02
NOMESCO Finland
Kolposcopy
38.7
323.0
2720
2923
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
323.0
339
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
+∞
323.0
2451
*
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
+∞
323.0
633
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
17.2
323.0
2287
3471
N87.1
ICD-10 Finland
Moderate cervical dysplasia
23.3
323.0
875
494
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
26.3
323.0
2117
1933
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
169.3
323.0
2099
310
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
239.4
227
*
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
+∞
162.8
155
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
6.5
146.4
407
691
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
+∞
142.7
136
*
115
Kela drug reimbursment
Breast cancer
+∞
142.7
136
*
PJA12
NOMESCO Finland
Sentinel node biopsy
151.2
124.1
131
9
LEB00
NOMESCO Finland
Biopsy of vagina
10.8
115.2
230
227
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
108.9
104
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
108.9
104
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.1
94.4
1751
11286
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
94.2
90
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
8.2
92.9
217
281
23400
ICD-8 Finland
Neoplasm of unspecified nature of uterus, Carcinoma in situ of cervix uteri
+∞
84.7
81
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
82.6
79
*
A04AA02
ATC
granisetron; systemic, transdermal
72.5
80.7
92
13
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
170.0
79.4
83
5
H02AB02
ATC
dexamethasone; systemic
11.4
78.4
151
138
8326
FHL
Batch conization
32.9
72.7
96
30
ZXC00
NOMESCO Finland
Use of diathermy
13.9
71.9
126
94
HAC20
NOMESCO Finland
Total mastectomy
153.2
71.2
75
5
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
71.1
68
*
18099
ICD-8 Finland
Malignant neoplasm of cervix uteri
+∞
67.9
65
*
130
Kela drug reimbursment
Malignant tumour
+∞
67.9
65
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
670.9
67.2
66
*
A04AA55
ATC
palonosetron, combinations; systemic
217.2
62.3
64
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
213.8
61.3
63
*
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
13.2
58.8
105
82
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.1
57.5
736
3862
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
179.3
51.0
53
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
14.5
47.5
81
57
L02BA01
ATC
tamoxifen; oral
40.0
47.0
59
15
L03AA13
ATC
pegfilgrastim; parenteral
+∞
44.9
43
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
37.9
44.1
56
15
L01BC06
ATC
capecitabine; oral
+∞
42.8
41
*
128
Kela drug reimbursment
Cancers of female genital organs
412.3
41.2
41
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
40.7
39
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
12.4
40.6
74
61
WF002
NOMESCO Finland
Radical radiotherapy
36.9
40.0
51
14
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
6.3
39.2
107
174
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
65.1
39.1
45
7
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
39.0
566
3075
XX3DW
NOMESCO Finland
Time consuming IT work
3.6
39.0
187
545
X86
ICPC
Abnormal cervix smear
5.2
38.9
124
244
ZX080
NOMESCO Finland
Image guided radiotherapy
103.7
37.8
41
*
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
+∞
37.6
36
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
361.0
36.0
36
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
81.0
35.9
40
5
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
79.0
34.9
39
5
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
124.6
34.7
37
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.5
34.0
278
1154
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
121.2
33.7
36
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
32.3
31
*
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
+∞
32.3
31
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.7
32.2
148
417
C50.99
ICD-10 Finland
Breast, unspecified
166.5
31.7
33
*
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
31.3
30
*
G01AA10
ATC
clindamycin; vaginal
1.7
30.8
786
5120
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
29.2
28
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
29.2
28
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
29.2
28
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
29.2
28
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
28.2
27
*
HA1AA
NOMESCO Finland
X-ray mammography
3.1
27.5
156
514
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
27.1
26
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
27.1
26
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
27.1
26
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
26.5
214
883
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
3.5
26.2
128
380
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
3.3
26.1
135
419
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
26.1
25
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
8.3
25.5
57
70
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
50.4
25.2
30
6
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
25.0
24
*
C50
ICD-10 Finland
Malignant neoplasm of breast
58.4
25.0
29
5
JN4AD
NOMESCO Finland
Body CT examination
4.5
25.0
90
204
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
14.8
24.7
41
28
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
48.7
24.3
29
6
L03AA02
ATC
filgrastim; parenteral
34.7
24.3
31
9
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
24.0
23
*
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
+∞
24.0
23
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
87.4
23.7
26
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
241.6
23.7
24
*
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
20.2
23.0
34
17
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
22.9
22
*
X76
ICPC
Malignant neoplasm breast female
+∞
22.9
22
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
22.9
22
*
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
9.0
22.7
48
54
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.5
22.7
110
325
A04AD12
ATC
aprepitant; systemic
231.4
22.6
23
*
18000
ICD-8 Finland
NA
+∞
21.9
21
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
21.9
21
*
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.6
21.8
164
649
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
17.2
21.8
34
20
NK6AN
NOMESCO Finland
Total body bone isotope imaging
38.9
21.7
27
7
N89.0
ICD-10 Finland
Mild vaginal dysplasia
8.6
21.3
46
54
ZX090
NOMESCO Finland
Other technic of radiotherapy
60.4
20.9
24
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
20.8
20
*
L02BG06
ATC
exemestane; oral
+∞
20.8
20
*
SPAT1193
SPAT
Pap smear
1.6
20.7
623
4187
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
18.4
20.4
31
17
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
19.8
19
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
19.8
19
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
19.8
19
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.5
19.5
160
665
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
40.3
19.5
24
6
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
19.3
108
357
TLC02
NOMESCO Finland
Simple extraction of IUD
2.0
19.1
244
1245
Z51.5
ICD-10 Finland
Palliative care
7.8
18.8
43
56
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
191.0
18.5
19
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
17.7
17
*
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
180.9
17.5
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.4
17.5
1391
11332
B01AB10
ATC
tinzaparin; parenteral
2.6
17.3
131
524
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
31.6
17.0
22
7
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
+∞
16.7
16
*
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
16.7
16
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
16.7
16
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
16.7
16
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
16.7
479
3165
N90.0
ICD-10 Finland
Mild vulvar dysplasia
8.4
16.7
36
43
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
90.5
16.6
18
*
Z51.0
ICD-10 Finland
Radiotherapy session
170.8
16.5
17
*
WX110
NOMESCO Finland
Local anesthesy
1.4
16.5
2344
20908
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
23.1
16.4
23
10
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
9.2
15.6
32
35
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
+∞
15.6
15
*
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
+∞
15.6
15
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
15.6
15
*
WF004
NOMESCO Finland
Palliative radiotherapy
160.7
15.5
16
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
15.4
897
6885
JN4BD
NOMESCO Finland
Extensive body CT
2.6
15.3
108
416
SPAT1263
SPAT
Sampling
1.3
15.1
1412
11719
N07BA03
ATC
varenicline; oral
2.1
15.1
177
875
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
56.9
14.8
17
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
5.9
14.6
40
68
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
14.6
14
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
14.6
14
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
14.6
14
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
14.6
14
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
14.6
14
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
14.6
14
*
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
+∞
14.6
14
*
X23
ICPC
Fear sexually transm dis female
1.6
14.0
337
2123
TQW20
NOMESCO Finland
Tatoe
23.9
13.8
19
8
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
75.4
13.6
15
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
13.5
13
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
13.5
13
*
N87
ICD-10 Finland
Dysplasia of cervix uteri
16.2
13.4
21
13
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.2
13.3
132
607
N02AA05
ATC
oxycodone; systemic
1.9
13.3
193
1036
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
12.5
275
1690
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
+∞
12.5
12
*
8500/3-C50.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-inner quadrant of breast
+∞
12.5
12
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
12.5
12
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
12.5
12
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
20.1
12.4
18
9
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
2.6
12.1
88
347
X92
ICPC
Chlamydia infection genital female
2.5
12.1
91
365
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
13.4
11.9
20
15
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.9
11.8
167
890
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
11.7
505
3646
8500/3-C50.5
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-outer quadrant of breast
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.5
11
*
ZX020
NOMESCO Finland
HDR radiotherapy within tissue
+∞
11.5
11
*
WX402
NOMESCO Finland
General anaesthesia
1.5
11.4
413
2869
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
11.4
87
352
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.7
11.3
37
79
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
7.0
11.3
27
39
XX1AD
NOMESCO Finland
Other CT-examination
35.1
11.3
14
*
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
10.6
11.2
21
20
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
11.2
352
2372
N76.0
ICD-10 Finland
Acute vaginitis
1.5
11.1
342
2295
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
10.1
11.0
21
21
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
10.4
10
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
+∞
10.4
10
*
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
+∞
10.4
10
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
10.4
10
*
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
+∞
10.4
10
*
XX1XN
NOMESCO Finland
Other isotope examination
+∞
10.4
10
*
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
+∞
10.4
10
*
A04AA01
ATC
ondansetron; systemic, rectal
2.2
10.4
101
464
LCD10
NOMESCO Finland
Vaginal hysterectomy
2.1
10.3
117
573
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.1
10.3
31
61
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
10.0
73
290
W11
ICPC
Contraception oral
1.4
10.0
556
4201
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
20.1
9.8
14
7
L02BG03
ATC
anastrozole; oral
15.1
9.5
15
10
N93.0
ICD-10 Finland
Postcoital and contact bleeding
3.0
9.5
51
169
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
7.5
9.4
21
28
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
9.4
9
*
394
Kela drug reimbursment
Palbociclib
+∞
9.4
9
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
9.4
9
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
1501
Kela drug reimbursment
Palbociclib
+∞
9.4
9
*
1CD02
NOMESCO Finland
NA
+∞
9.4
9
*
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
7.3
9.2
21
29
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
13.7
9.2
15
11
ZXC96
NOMESCO Finland
Robot assisted procedure
4.7
9.0
29
62
SPAT1301
SPAT
No procedures
1.3
8.8
876
7205
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.7
981
8198
D06BB04
ATC
podophyllotoxin; topical
1.6
8.7
253
1674
4044
NOMESCO Finland
NA
14.0
8.7
14
10
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
50.1
8.7
10
*
SPAT1312
SPAT
General health counselling
1.3
8.5
1047
8835
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
27.6
8.5
11
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
90.3
8.4
9
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
90.3
8.4
9
*
SPAT1153
SPAT
Removal of sutures
1.3
8.4
680
5432
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
8.3
8
*
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
+∞
8.3
8
*
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
+∞
8.3
8
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
8.2
1322
11504
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.2
781
6381
D06BB10
ATC
imiquimod; topical
1.8
8.1
145
842
X85
ICPC
Cervical disease NOS
8.9
8.0
16
18
WZC30
NOMESCO Finland
Teaching
1.6
7.9
211
1368
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.1
7.9
81
383
SPAT1308
SPAT
Sexual health counselling
1.3
7.9
762
6229
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
7.8
774
6345
N02BE01
ATC
paracetamol; systemic, rectal
1.3
7.8
2692
25389
ZZR00
NOMESCO Finland
Flap of skin
7.0
7.8
18
26
A79
ICPC
Malignancy NOS
45.1
7.7
9
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
45.1
7.7
9
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
7.6
248
1682
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
25.1
7.6
10
*
T74.1
ICD-10 Finland
Physical abuse
2.1
7.4
75
353
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
80.3
7.4
8
*
T810, N872
ICD-10 Finland
NA
+∞
7.3
7
*
8500/3-C50.8
ICD-O-3
Infiltrating duct carcinoma, NOS, of overlapping lesion of breast
+∞
7.3
7
*
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
7.3
7
*
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
+∞
7.3
7
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
7.3
7
*
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
+∞
7.3
7
*
C50.52
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, lobular tumor
+∞
7.3
7
*
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
+∞
7.3
7
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
7.3
7
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.8
7.2
108
593
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
7.0
36
118
J01DB01
ATC
cefalexin; oral
1.2
7.0
2658
25124
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.5
6.9
52
212
SPAT1283
SPAT
Restricted health certificate
1.3
6.9
840
7052
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
6.8
2446
22927
N06AX11
ATC
mirtazapine; oral
1.2
6.8
881
7447
HAB99
NOMESCO Finland
Other partial excision of mammary gland
3.0
6.8
36
121
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.3
6.8
19
36
ZX120
NOMESCO Finland
Intravenous
1.6
6.6
153
961
SPAT1238
SPAT
Brief therapy
1.9
6.5
89
475
N05CF01
ATC
zopiclone; oral
1.3
6.5
705
5827
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.5
6.5
49
200
D82
ICPC
Teeth/gum disease
1.2
6.5
1181
10348
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
2.8
6.4
38
136
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
6.4
358
4611
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
70.0
6.4
7
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
70.0
6.4
7
*
PJD63
NOMESCO Finland
Laparoscopic dissection of aortic lymph nodes
70.0
6.4
7
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
6.3
87
466
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
6.2
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.2
6
*
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
+∞
6.2
6
*
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
6.2
6
*
YX9CD
NOMESCO Finland
Other very extensive CT eamination for dose design of radiotherapy
+∞
6.2
6
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
6.2
6
*
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
+∞
6.2
6
*
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
+∞
6.2
6
*
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
+∞
6.2
6
*
L02BA03
ATC
fulvestrant; parenteral
+∞
6.2
6
*
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
+∞
6.2
6
*
192
Kela drug reimbursment
Fulvestrant
+∞
6.2
6
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
6.2
6
*
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
+∞
6.2
6
*
L01XE33
ATC
[U] palbociclib; oral
+∞
6.2
6
*
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
4.3
6.2
21
49
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
6.2
905
7741
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.2
1028
8910
LCH11
NOMESCO Finland
Pharmacologic abortion
1.4
6.1
244
1730
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
5.7
6.1
16
28
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
6.1
66
324
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
4.0
6.1
22
55
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.2
6.0
58
269
Mortality – FinRegistry
↥Association
Association between endpoint CD2_INSITU_CERVIX_UTERI_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_INSITU_CERVIX_UTERI_EXALLC | 1.416 [1.21, 1.65] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.175 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 3908 females with CD2_INSITU_CERVIX_UTERI_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_INSITU_CERVIX_UTERI_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.151% | No data |
| 5 | 0.802% | No data |
| 10 | 1.94% | No data |
| 15 | 3.761% | No data |
| 20 | 6.487% | No data |
Relationships between endpoints
↥Index endpoint: CD2_INSITU_CERVIX_UTERI_EXALLC – Carcinoma in situ of cervix uteri
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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