Carcinoma in situ of cervix uteri

CD2_INSITU_CERVIX_UTERI_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

  • not C3_CERVIX_UTERI
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06
  • Cause of death: ICD-10 D06
  • Cancer registry: Topography ICD-O-3 C53
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D00-D09
Name in latin
Carcinoma in situ vaginae

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5402 5402 -
Only index persons 5151 5151 -
Unadjusted period prevalence (%)
Whole population 0.15 0.15 -
Only index persons 0.19 0.19 -
Median age at first event (years)
Whole population - 36.09 -
Only index persons - 35.80 -

-FinnGen-

Key figures

All Female Male
Number of individuals 3866 3866 -
Unadjusted period prevalence (%) 1.32 1.32 -
Median age at first event (years) 35.40 35.40 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3487
Matched controls
34870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
26.3
323.0
2117
1933
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
323.0
339
*
LDA10
NOMESCO Finland
Curettage of cervix uteri
16.7
323.0
1146
994
N87.1
ICD-10 Finland
Moderate cervical dysplasia
23.3
323.0
875
494
ULA02
NOMESCO Finland
Kolposcopy
38.7
323.0
2720
2923
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
85.4
323.0
2394
871
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
+∞
323.0
633
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
17.2
323.0
2287
3471
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
+∞
323.0
2451
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
25.4
323.0
2461
3005
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
169.3
323.0
2099
310
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
239.4
227
*
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
+∞
162.8
155
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
6.5
146.4
407
691
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
+∞
142.7
136
*
115
Kela drug reimbursment
Breast cancer
+∞
142.7
136
*
PJA12
NOMESCO Finland
Sentinel node biopsy
151.2
124.1
131
9
LEB00
NOMESCO Finland
Biopsy of vagina
10.8
115.2
230
227
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
108.9
104
*
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
108.9
104
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.1
94.4
1751
11286
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
94.2
90
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
8.2
92.9
217
281
23400
ICD-8 Finland
Neoplasm of unspecified nature of uterus, Carcinoma in situ of cervix uteri
+∞
84.7
81
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
82.6
79
*
A04AA02
ATC
granisetron; systemic, transdermal
72.5
80.7
92
13
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
170.0
79.4
83
5
H02AB02
ATC
dexamethasone; systemic
11.4
78.4
151
138
8326
FHL
Batch conization
32.9
72.7
96
30
ZXC00
NOMESCO Finland
Use of diathermy
13.9
71.9
126
94
HAC20
NOMESCO Finland
Total mastectomy
153.2
71.2
75
5
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
71.1
68
*
130
Kela drug reimbursment
Malignant tumour
+∞
67.9
65
*
18099
ICD-8 Finland
Malignant neoplasm of cervix uteri
+∞
67.9
65
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
670.9
67.2
66
*
A04AA55
ATC
palonosetron, combinations; systemic
217.2
62.3
64
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
213.8
61.3
63
*
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
13.2
58.8
105
82
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.1
57.5
736
3862
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
179.3
51.0
53
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
14.5
47.5
81
57
L02BA01
ATC
tamoxifen; oral
40.0
47.0
59
15
L03AA13
ATC
pegfilgrastim; parenteral
+∞
44.9
43
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
37.9
44.1
56
15
L01BC06
ATC
capecitabine; oral
+∞
42.8
41
*
128
Kela drug reimbursment
Cancers of female genital organs
412.3
41.2
41
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
40.7
39
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
12.4
40.6
74
61
WF002
NOMESCO Finland
Radical radiotherapy
36.9
40.0
51
14
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
6.3
39.2
107
174
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
65.1
39.1
45
7
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
39.0
566
3075
XX3DW
NOMESCO Finland
Time consuming IT work
3.6
39.0
187
545
X86
ICPC
Abnormal cervix smear
5.2
38.9
124
244
ZX080
NOMESCO Finland
Image guided radiotherapy
103.7
37.8
41
*
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
+∞
37.6
36
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
361.0
36.0
36
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
81.0
35.9
40
5
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
79.0
34.9
39
5
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
124.6
34.7
37
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.5
34.0
278
1154
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
121.2
33.7
36
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
32.3
31
*
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
+∞
32.3
31
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.7
32.2
148
417
C50.99
ICD-10 Finland
Breast, unspecified
166.5
31.7
33
*
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
31.3
30
*
G01AA10
ATC
clindamycin; vaginal
1.7
30.8
786
5120
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
29.2
28
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
29.2
28
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
29.2
28
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
29.2
28
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
28.2
27
*
HA1AA
NOMESCO Finland
X-ray mammography
3.1
27.5
156
514
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
27.1
26
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
27.1
26
*
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
27.1
26
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
26.5
214
883
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
3.5
26.2
128
380
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
3.3
26.1
135
419
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
26.1
25
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
8.3
25.5
57
70
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
50.4
25.2
30
6
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
25.0
24
*
C50
ICD-10 Finland
Malignant neoplasm of breast
58.4
25.0
29
5
JN4AD
NOMESCO Finland
Body CT examination
4.5
25.0
90
204
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
14.8
24.7
41
28
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
48.7
24.3
29
6
L03AA02
ATC
filgrastim; parenteral
34.7
24.3
31
9
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
24.0
23
*
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
+∞
24.0
23
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
87.4
23.7
26
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
241.6
23.7
24
*
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
20.2
23.0
34
17
X76
ICPC
Malignant neoplasm breast female
+∞
22.9
22
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
22.9
22
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
22.9
22
*
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
9.0
22.7
48
54
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.5
22.7
110
325
A04AD12
ATC
aprepitant; systemic
231.4
22.6
23
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
21.9
21
*
18000
ICD-8 Finland
NA
+∞
21.9
21
*
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.6
21.8
164
649
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
17.2
21.8
34
20
NK6AN
NOMESCO Finland
Total body bone isotope imaging
38.9
21.7
27
7
N89.0
ICD-10 Finland
Mild vaginal dysplasia
8.6
21.3
46
54
ZX090
NOMESCO Finland
Other technic of radiotherapy
60.4
20.9
24
*
L02BG06
ATC
exemestane; oral
+∞
20.8
20
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
20.8
20
*
SPAT1193
SPAT
Pap smear
1.6
20.7
623
4187
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
18.4
20.4
31
17
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
19.8
19
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
19.8
19
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
19.8
19
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.5
19.5
160
665
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
40.3
19.5
24
6
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
19.3
108
357
TLC02
NOMESCO Finland
Simple extraction of IUD
2.0
19.1
244
1245
Z51.5
ICD-10 Finland
Palliative care
7.8
18.8
43
56
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
191.0
18.5
19
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
17.7
17
*
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
180.9
17.5
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.4
17.5
1391
11332
B01AB10
ATC
tinzaparin; parenteral
2.6
17.3
131
524
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
31.6
17.0
22
7
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
16.7
16
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
16.7
16
*
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
+∞
16.7
16
*
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
16.7
16
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
16.7
479
3165
N90.0
ICD-10 Finland
Mild vulvar dysplasia
8.4
16.7
36
43
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
90.5
16.6
18
*
Z51.0
ICD-10 Finland
Radiotherapy session
170.8
16.5
17
*
WX110
NOMESCO Finland
Local anesthesy
1.4
16.5
2344
20908
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
23.1
16.4
23
10
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
9.2
15.6
32
35
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
+∞
15.6
15
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
15.6
15
*
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
+∞
15.6
15
*
WF004
NOMESCO Finland
Palliative radiotherapy
160.7
15.5
16
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
15.4
897
6885
JN4BD
NOMESCO Finland
Extensive body CT
2.6
15.3
108
416
SPAT1263
SPAT
Sampling
1.3
15.1
1412
11719
N07BA03
ATC
varenicline; oral
2.1
15.1
177
875
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
56.9
14.8
17
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
5.9
14.6
40
68
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
14.6
14
*
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
+∞
14.6
14
*
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
+∞
14.6
14
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
14.6
14
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
14.6
14
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
14.6
14
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
14.6
14
*
X23
ICPC
Fear sexually transm dis female
1.6
14.0
337
2123
TQW20
NOMESCO Finland
Tatoe
23.9
13.8
19
8
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
75.4
13.6
15
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
13.5
13
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
13.5
13
*
N87
ICD-10 Finland
Dysplasia of cervix uteri
16.2
13.4
21
13
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
2.2
13.3
132
607
N02AA05
ATC
oxycodone; systemic
1.9
13.3
193
1036
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
12.5
275
1690
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
+∞
12.5
12
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
12.5
12
*
8500/3-C50.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-inner quadrant of breast
+∞
12.5
12
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
12.5
12
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
20.1
12.4
18
9
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
2.6
12.1
88
347
X92
ICPC
Chlamydia infection genital female
2.5
12.1
91
365
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
13.4
11.9
20
15
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.9
11.8
167
890
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
11.7
505
3646
8500/3-C50.5
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-outer quadrant of breast
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.5
11
*
ZX020
NOMESCO Finland
HDR radiotherapy within tissue
+∞
11.5
11
*
WX402
NOMESCO Finland
General anaesthesia
1.5
11.4
413
2869
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
11.4
87
352
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.7
11.3
37
79
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
7.0
11.3
27
39
XX1AD
NOMESCO Finland
Other CT-examination
35.1
11.3
14
*
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
10.6
11.2
21
20
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
11.2
352
2372
N76.0
ICD-10 Finland
Acute vaginitis
1.5
11.1
342
2295
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
10.1
11.0
21
21
XX1XN
NOMESCO Finland
Other isotope examination
+∞
10.4
10
*
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
+∞
10.4
10
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
10.4
10
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
10.4
10
*
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
+∞
10.4
10
*
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
+∞
10.4
10
*
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
+∞
10.4
10
*
A04AA01
ATC
ondansetron; systemic, rectal
2.2
10.4
101
464
LCD10
NOMESCO Finland
Vaginal hysterectomy
2.1
10.3
117
573
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.1
10.3
31
61
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
10.0
73
290
W11
ICPC
Contraception oral
1.4
10.0
556
4201
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
20.1
9.8
14
7
L02BG03
ATC
anastrozole; oral
15.1
9.5
15
10
N93.0
ICD-10 Finland
Postcoital and contact bleeding
3.0
9.5
51
169
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
7.5
9.4
21
28
1CD02
NOMESCO Finland
NA
+∞
9.4
9
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
9.4
9
*
394
Kela drug reimbursment
Palbociclib
+∞
9.4
9
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
9.4
9
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
1501
Kela drug reimbursment
Palbociclib
+∞
9.4
9
*
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
7.3
9.2
21
29
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
13.7
9.2
15
11
ZXC96
NOMESCO Finland
Robot assisted procedure
4.7
9.0
29
62
SPAT1301
SPAT
No procedures
1.3
8.8
876
7205
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.7
981
8198
D06BB04
ATC
podophyllotoxin; topical
1.6
8.7
253
1674
4044
NOMESCO Finland
NA
14.0
8.7
14
10
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
50.1
8.7
10
*
SPAT1312
SPAT
General health counselling
1.3
8.5
1047
8835
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
27.6
8.5
11
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
90.3
8.4
9
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
90.3
8.4
9
*
SPAT1153
SPAT
Removal of sutures
1.3
8.4
680
5432
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
+∞
8.3
8
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
8.3
8
*
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
+∞
8.3
8
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
8.2
1322
11504
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.2
781
6381
D06BB10
ATC
imiquimod; topical
1.8
8.1
145
842
X85
ICPC
Cervical disease NOS
8.9
8.0
16
18
WZC30
NOMESCO Finland
Teaching
1.6
7.9
211
1368
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.1
7.9
81
383
SPAT1308
SPAT
Sexual health counselling
1.3
7.9
762
6229
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
7.8
774
6345
N02BE01
ATC
paracetamol; systemic, rectal
1.3
7.8
2692
25389
ZZR00
NOMESCO Finland
Flap of skin
7.0
7.8
18
26
A79
ICPC
Malignancy NOS
45.1
7.7
9
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
45.1
7.7
9
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
7.6
248
1682
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
25.1
7.6
10
*
T74.1
ICD-10 Finland
Physical abuse
2.1
7.4
75
353
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
80.3
7.4
8
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
7.3
7
*
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
+∞
7.3
7
*
8500/3-C50.8
ICD-O-3
Infiltrating duct carcinoma, NOS, of overlapping lesion of breast
+∞
7.3
7
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
7.3
7
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
7.3
7
*
C50.52
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, lobular tumor
+∞
7.3
7
*
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
+∞
7.3
7
*
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
7.3
7
*
T810, N872
ICD-10 Finland
NA
+∞
7.3
7
*
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
+∞
7.3
7
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.8
7.2
108
593
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.1
7.0
36
118
J01DB01
ATC
cefalexin; oral
1.2
7.0
2658
25124
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.5
6.9
52
212
SPAT1283
SPAT
Restricted health certificate
1.3
6.9
840
7052
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
6.8
2446
22927
N06AX11
ATC
mirtazapine; oral
1.2
6.8
881
7447
HAB99
NOMESCO Finland
Other partial excision of mammary gland
3.0
6.8
36
121
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.3
6.8
19
36
ZX120
NOMESCO Finland
Intravenous
1.6
6.6
153
961
SPAT1238
SPAT
Brief therapy
1.9
6.5
89
475
N05CF01
ATC
zopiclone; oral
1.3
6.5
705
5827
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.5
6.5
49
200
D82
ICPC
Teeth/gum disease
1.2
6.5
1181
10348
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
2.8
6.4
38
136
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
6.4
358
4611
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
70.0
6.4
7
*
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
70.0
6.4
7
*
PJD63
NOMESCO Finland
Laparoscopic dissection of aortic lymph nodes
70.0
6.4
7
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
6.3
87
466
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
+∞
6.2
6
*
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
+∞
6.2
6
*
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
+∞
6.2
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.2
6
*
192
Kela drug reimbursment
Fulvestrant
+∞
6.2
6
*
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
+∞
6.2
6
*
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
6.2
6
*
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
+∞
6.2
6
*
YX9CD
NOMESCO Finland
Other very extensive CT eamination for dose design of radiotherapy
+∞
6.2
6
*
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
+∞
6.2
6
*
L01XE33
ATC
[U] palbociclib; oral
+∞
6.2
6
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
6.2
6
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
6.2
6
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
6.2
6
*
L02BA03
ATC
fulvestrant; parenteral
+∞
6.2
6
*
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
4.3
6.2
21
49
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
6.2
905
7741
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.2
1028
8910
LCH11
NOMESCO Finland
Pharmacologic abortion
1.4
6.1
244
1730
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
5.7
6.1
16
28
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.1
6.1
66
324
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
4.0
6.1
22
55
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.2
6.0
58
269

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2478
12312
3.82
307.65
3.1
1.7
—
—
—
0
0
934
881
13.66
307.65
2.6
1.6
—
—
—
0
0
554
835
7.58
307.65
1.4
1.2
—
—
—
0
0
67
57
11.94
66.15
3.0
1.2
36.2
39.7
u/ml
0.04
62
52
41
14
29.59
61.60
1.8
1.0
1.7
2.1
ug/l
—
25
7
42
28
15.15
47.68
4.8
1.1
28.8
24.9
u/ml
0.14
42
28
229
945
2.51
35.33
3.6
1.6
11.3
18.3
ug/l
0.19
181
641
551
3193
1.85
35.18
1.3
1.1
—
—
—
0
0
1832
15268
1.38
20.79
3.9
3.8
—
—
—
0
0
34
61
5.61
18.19
1.2
1.1
—
—
—
0
0
327
1994
1.70
17.01
2.3
1.5
32.6
27.2
u/ml
0.48
314
1923
1528
12687
1.34
16.39
5.4
3.3
9.0
9.7
umol/l
4.13
1437
11762
1374
11337
1.33
15.02
5.8
4.5
1.2
1.2
mmol/l
0.98
1126
9556
1235
10091
1.33
14.27
4.5
3.6
36.6
36.9
g/l
0.92
1156
9309
24
39
6.19
14.19
5.5
1.4
—
—
—
0
0
1148
9336
1.33
13.56
1.9
1.8
—
—
—
0
0
559
4104
1.42
12.43
2.2
2.2
4996.3
6610.1
u/l
0.63
219
1796
1210
10019
1.30
12.28
5.0
4.1
1.2
1.2
mmol/l
1.09
1076
8996
433
3055
1.47
11.89
3.5
3.2
—
—
—
0
0
2337
21086
1.27
11.67
6.9
5.1
70.8
70.4
u/l
0.23
2177
19708
1077
8831
1.30
11.63
3.8
3.5
0.0
0.0
estimate
0.13
456
3363
96
445
2.19
11.50
1.3
1.2
—
—
—
0
0
258
1657
1.60
10.93
2.1
2.2
0.2
0.2
g/l
0.76
237
1543
976
7997
1.29
10.40
5.8
5.4
1.1
1.1
inr
1.33
360
2762
990
8130
1.29
10.36
3.0
1.8
2.3
2.3
mmol/l
0.34
895
7149
269
1769
1.56
10.31
3.2
2.3
1.2
1.2
mmol/l
0.36
228
1468
1452
12649
1.24
8.91
2.1
2.0
—
—
—
0
0
625
4927
1.32
8.70
3.6
3.3
—
—
—
0
0
3259
31046
1.32
8.64
10.4
8.8
3.9
3.9
mmol/l
0.37
3127
30038
1877
16833
1.22
8.62
3.6
3.3
0.0
0.0
estimate
2.27
449
3356
843
6934
1.28
8.47
1.8
1.8
—
—
—
0
0
1861
16718
1.22
8.26
4.8
4.4
0.0
0.0
estimate
1.34
461
3398
3247
30956
1.31
8.26
10.3
8.8
139.5
139.5
mmol/l
0.43
3125
30037
151
919
1.67
8.01
3.7
4.8
—
—
—
0
0
1872
16864
1.21
7.96
8.3
6.6
4.0
4.1
e9/l
0.11
1698
14789
421
3175
1.37
7.86
3.0
2.3
0.8
0.8
mmol/l
2.00
390
2937
288
2040
1.44
7.73
3.9
3.8
1.2
0.3
%
0.72
61
284
12
8
15.04
7.71
1.3
1.0
—
—
—
0
0
1847
16666
1.21
7.58
3.5
3.2
0.0
0.0
estimate
1.15
442
3295
3403
32729
1.33
7.56
10.9
9.1
19.5
17.9
mg/l
2.08
2646
24812
1543
13719
1.21
7.30
8.5
7.1
0.0
0.0
e9/l
1.93
1334
11272
1340
11761
1.21
7.24
1.8
1.8
—
—
—
0
0
742
6120
1.26
7.17
2.9
2.8
—
—
—
0
0
939
7965
1.24
7.06
4.2
3.8
—
—
—
0
0
292
2115
1.41
6.95
4.2
4.1
0.1
0.0
%
0.68
74
338
1127
9755
1.22
6.95
3.3
2.8
—
—
—
0
0
233
1625
1.46
6.81
4.3
2.9
—
—
—
0
0
299
2185
1.40
6.77
4.2
4.0
0.8
0.4
%
0.68
76
359
795
6652
1.25
6.74
3.7
2.9
7.4
7.4
ph
0.17
185
1178
995
8534
1.22
6.67
2.5
2.2
51.6
56.0
u/l
3.31
911
7895
284
2065
1.41
6.62
4.1
4.1
0.0
0.3
%
0.52
63
306
92
515
1.81
6.62
2.8
2.5
7.4
7.4
ph
1.21
73
418
214
1479
1.47
6.56
6.2
6.7
95.1
96.0
%
0.75
203
1418
2838
29795
0.82
6.50
13.3
11.7
332.4
331.9
g/l
1.89
2816
29564
46
201
2.30
6.50
1.0
1.0
—
—
—
0
0
2507
23443
1.20
6.47
3.8
3.7
9.6
9.5
mm/h
0.04
2322
22080
2484
23209
1.20
6.46
4.2
3.9
—
—
—
0
0
1744
15822
1.19
6.29
4.0
3.5
6.2
6.3
mmol/l
0.45
1551
13919
2411
22495
1.19
6.26
4.1
4.0
1983.3
1677.0
e6/l
0.08
19
237
241
1722
1.43
6.21
6.2
6.2
12.9
13.0
kpa
0.03
229
1636
241
1722
1.43
6.21
6.2
6.2
5.0
5.0
kpa
0.29
228
1639
1078
9399
1.20
6.01
2.6
2.5
—
—
—
0
0
3587
34947
1.37
5.85
10.6
8.8
—
—
—
0
0
71
382
1.87
5.84
4.3
2.3
103.1
52.5
u/ml
0.46
59
305
70
376
1.88
5.79
2.3
2.0
17.3
17.0
%
0.23
39
181
970
8402
1.21
5.76
2.6
2.6
35.7
35.8
ng/l
0.00
414
3499
1069
9347
1.20
5.73
5.7
5.5
—
—
—
0
0
47
221
2.14
5.62
3.1
2.6
1.0
1.1
%
0.04
34
168
75
420
1.80
5.46
3.0
2.6
2.1
2.2
mmol/l
0.10
38
242
415
3296
1.29
5.40
1.5
1.6
—
—
—
0
0
197
1395
1.43
5.38
7.1
7.0
119.7
121.6
g/l
0.73
189
1338
236
1727
1.39
5.34
6.2
6.2
0.7
0.8
mmol/l
0.14
174
1266
110
699
1.59
5.05
1.3
1.3
—
—
—
0
0
409
3277
1.28
4.97
1.8
1.8
—
—
—
0
0
99
625
1.60
4.69
5.0
4.8
0.9
0.9
%
0.71
94
586
102
651
1.58
4.62
1.3
1.3
167.8
104.1
u/ml
0.84
25
149
140
958
1.48
4.61
6.2
6.4
24.4
24.1
mmol/l
0.37
129
881
3487
33982
1.27
4.54
8.8
7.4
23.3
23.2
u/l
0.12
3362
32927
591
4985
1.22
4.53
2.9
2.4
519.6
527.0
mosm/kgh2o
0.33
502
4183
98
623
1.59
4.53
5.0
4.7
1.7
1.7
%
0.11
92
584
278
2146
1.32
4.49
2.7
2.9
—
—
—
0
0
431
3522
1.25
4.44
2.4
2.2
2.4
2.5
g/l
0.80
383
3255
69
406
1.71
4.32
2.9
2.5
—
—
—
0
0
144
1008
1.45
4.25
3.1
2.7
—
—
—
0
0
96
622
1.56
4.12
3.3
4.2
—
—
—
0
0
653
5610
1.20
4.12
1.7
1.6
—
—
—
0
0
266
2067
1.31
4.12
7.1
5.4
104.6
104.8
mmol/l
0.32
257
2018
58
330
1.77
4.09
5.1
7.0
11.3
11.0
mmol/l
0.30
53
295
58
331
1.76
4.06
5.1
7.0
105.6
105.1
mmol/l
0.40
53
296
78
485
1.62
3.99
4.3
3.6
—
—
—
0
0
205
1543
1.35
3.97
4.8
3.4
5.8
5.8
kpa
0.21
198
1482
2415
22909
1.14
3.95
2.8
2.6
36.2
30.6
u/l
2.49
2291
21850
1661
15380
1.14
3.90
5.6
5.4
0.0
0.0
e9/l
0.13
1503
13562
1650
15313
1.14
3.67
5.6
5.4
0.5
0.5
e9/l
0.15
1500
13545
200
1528
1.33
3.54
4.9
3.4
1.8
1.7
mmol/l
0.10
154
1213
1185
10790
1.14
3.49
1.7
1.8
—
—
—
0
0
1714
15982
1.13
3.47
5.7
5.6
0.2
0.2
e9/l
0.42
1581
14370
30
146
2.06
3.41
2.3
2.5
—
—
—
0
0
50
290
1.73
3.37
2.7
2.4
—
—
—
0
0
3757
37126
1.42
3.31
16.2
14.0
6.9
6.8
e9/l
2.56
3682
36319
1541
14310
1.13
3.29
5.6
5.4
2.6
2.8
%
1.90
1443
13333
171
1293
1.34
3.27
2.0
2.3
67.5
73.1
e9/l
1.32
133
943
1968
18552
1.12
3.24
2.7
2.7
—
—
—
0
0
3756
37122
1.41
3.23
16.2
13.9
4.4
4.5
e12/l
10.54
3680
36348
1547
14388
1.13
3.19
5.8
5.6
7.8
7.8
%
0.12
1461
13531
3757
37138
1.41
3.18
16.2
14.0
132.7
133.0
g/l
0.83
3716
36769
3755
37115
1.41
3.18
16.1
13.8
30.2
30.0
pg
20.09
3715
36753
269
2169
1.26
3.17
2.4
2.3
10.3
10.5
g/l
0.60
244
2004
184
1413
1.32
3.17
1.3
1.2
—
—
—
0
0
3755
37117
1.41
3.16
16.1
13.9
90.7
90.0
fl
20.92
3714
36757
31
158
1.97
3.14
1.3
1.2
—
—
—
0
0
3752
37090
1.39
3.07
16.2
13.9
268.0
269.0
e9/l
0.44
3686
36358
472
4047
1.19
3.05
2.6
1.9
2.4
2.4
mmol/l
0.73
410
3448
794
7097
1.15
3.02
2.7
2.6
0.4
0.3
e6/l
0.87
599
5175
1481
13778
1.12
2.99
5.7
5.5
0.6
0.7
%
1.69
1388
12826
166
1269
1.32
2.97
4.4
2.8
4.3
4.6
kpa
1.23
159
1219
53
326
1.63
2.92
2.6
2.4
6.7
7.4
mmol/l
0.99
53
316
263
2138
1.25
2.91
2.6
2.1
—
—
—
0
0
226
1805
1.27
2.91
2.7
2.2
—
—
—
0
0
33
177
1.87
2.90
2.3
2.0
—
—
—
0
0
110
793
1.40
2.87
8.3
8.2
—
—
—
0
0
50
306
1.64
2.82
3.5
2.6
31.8
32.7
umol/l
0.13
44
268
208
1655
1.27
2.78
1.6
1.6
1.2
1.3
g/l
1.52
190
1541
460
3970
1.18
2.76
2.4
2.2
14.8
14.6
umol/l
0.22
412
3669
5
6
8.34
2.75
1.0
1.0
0.9
6.6
u/ml
—
5
6
22
104
2.12
2.74
2.1
1.2
—
—
—
0
0
369
3129
1.20
2.71
2.6
2.3
24.8
24.0
%
0.43
306
2693
73
493
1.49
2.71
2.0
1.8
2.2
1.3
ug/l
0.50
62
425
172
1342
1.29
2.69
8.9
6.7
8.9
7.5
mmol/l
1.66
161
1282
473
4105
1.17
2.66
1.7
1.7
1245.6
1188.5
nmol/l
0.73
366
3179
434
5009
0.85
2.63
1.2
1.3
—
—
—
0
0
38
221
1.73
2.61
1.7
1.6
1.3
1.3
promille
0.00
26
174
280
2322
1.22
2.60
2.5
2.1
—
—
—
0
0
345
2921
1.20
2.59
2.7
2.0
5.9
5.3
umol/l
0.33
280
2404
55
353
1.57
2.59
2.5
2.3
1.4
1.4
mmol/l
0.03
55
343
281
2334
1.22
2.57
2.5
2.0
—
—
—
0
0
403
3464
1.18
2.55
1.3
1.3
23.0
22.8
iu/l
0.05
367
3021
104
762
1.37
2.51
4.5
2.5
0.6
0.7
%
0.41
95
722
281
2341
1.22
2.50
2.5
2.1
—
—
—
0
0
267
2214
1.22
2.49
1.3
1.2
—
—
—
0
0
1690
15953
1.11
2.47
5.6
5.4
2.0
2.0
e9/l
0.09
1562
14406
2907
28225
1.12
2.44
4.3
4.4
14.4
14.3
pmol/l
3.32
2683
26568
855
7784
1.13
2.43
2.9
2.7
53.4
65.3
e6/l
0.18
642
5734
265
2207
1.22
2.38
1.4
1.3
—
—
—
0
0
28
153
1.84
2.38
1.1
1.1
3.0
4.2
u/ml
0.16
16
85
27
146
1.86
2.37
3.0
2.4
60.3
55.4
%
0.40
17
93
786
7132
1.13
2.35
2.6
2.5
—
—
—
0
0
234
1938
1.22
2.24
2.2
2.3
1.6
1.7
%
0.62
204
1702
41
256
1.61
2.20
3.8
1.2
173.9
114.2
u/ml
0.15
16
72
15
310
0.48
2.19
1.2
1.5
—
—
—
0
0
23
122
1.89
2.15
1.3
1.2
—
—
—
0
0
1591
15048
1.10
2.15
5.7
5.4
29.4
30.0
%
1.72
1490
14104
7
19
3.69
2.15
10.6
9.7
5.5
5.8
mmol/l
—
7
19
16
74
2.17
2.14
1.4
2.1
—
—
—
0
0
118
906
1.31
2.14
7.9
7.6
91.9
93.8
%
1.09
118
901
94
701
1.35
2.09
1.3
1.2
321.2
261.6
u/ml
1.12
70
480
363
3151
1.17
2.08
2.0
1.9
28.7
29.0
s
0.76
348
3019
1573
14889
1.10
2.07
5.4
5.2
56.7
56.5
%
0.36
1476
13994
242
2029
1.21
2.07
3.4
3.2
—
—
—
0
0
82
600
1.37
2.05
4.6
5.0
1.2
1.2
mmol/l
0.15
75
526
624
5630
1.13
2.05
1.6
1.6
93834733.8
32979803.8
pmol/l
0.68
519
4897
782
7152
1.12
2.04
3.7
3.5
1.0
1.0
kg/l
0.94
110
1105
14
63
2.23
2.00
2.4
3.0
—
—
—
0
0
57
393
1.46
1.99
1.4
1.5
—
—
—
0
0
26
439
0.59
1.98
2.1
2.2
—
—
—
0
0
39
249
1.57
1.95
3.6
5.2
6.3
6.7
mmol/l
0.26
32
200
12
51
2.36
1.95
1.4
1.6
—
—
—
0
0
118
1499
0.78
1.92
1.1
1.1
—
—
—
0
0
1091
10183
1.10
1.91
3.3
3.1
72.6
77.0
e6/l
0.10
721
6403
3230
31669
1.12
1.91
4.9
5.0
1.7
1.9
mu/l
1.37
3002
30075
691
6301
1.12
1.90
3.3
2.9
97.0
98.2
%
0.66
668
6073
71
515
1.39
1.90
1.2
1.1
—
—
—
0
0
48
324
1.49
1.88
1.1
1.1
—
—
—
0
0
9
34
2.65
1.86
1.3
1.1
—
—
—
0
0
2941
28705
1.10
1.86
12.7
11.0
13.4
13.4
%
0.69
2881
28119
242
2841
0.84
1.85
1.4
1.5
—
—
—
0
0
132
1051
1.26
1.85
3.3
2.7
7.4
7.4
ph
0.63
31
143
164
1340
1.23
1.84
9.1
6.8
—
—
—
0
0
603
5469
1.12
1.83
2.5
2.3
9.8
8.8
e6/l
0.37
516
4680
133
1065
1.26
1.79
3.3
2.7
5.3
5.1
kpa
1.50
126
994
43
287
1.50
1.79
1.2
1.2
—
—
—
0
0
285
2463
1.17
1.76
6.1
4.5
1.1
1.0
mmol/l
0.21
263
2290
43
629
0.68
1.76
1.2
1.2
2.5
4.2
u/ml
1.61
21
261
19
102
1.87
1.76
1.3
1.2
36.4
33.0
mmol/l
0.27
19
91
269
2315
1.17
1.75
2.5
2.0
—
—
—
0
0
64
469
1.37
1.65
2.3
2.0
134.7
131.3
g/l
0.68
52
356
244
2829
0.85
1.64
1.4
1.5
—
—
—
0
0
6
20
3.00
1.58
1.8
1.8
—
—
—
0
0
52
371
1.41
1.58
2.3
1.7
—
—
—
0
0
124
1003
1.24
1.57
1.3
1.3
18.6
19.6
u/l
0.14
93
818
25
152
1.65
1.56
6.0
7.2
11.9
11.4
mg/l
0.21
25
140
130
1058
1.24
1.56
1.9
1.4
—
—
—
0
0
253
2904
0.86
1.51
1.5
1.5
—
—
—
0
0
213
1826
1.18
1.49
1.3
1.4
—
—
—
0
0
819
7628
1.09
1.49
2.1
2.1
2.7
2.6
mg/l
0.42
702
6559
67
505
1.33
1.47
2.8
2.1
—
—
—
0
0
451
4078
1.12
1.47
2.4
2.3
1.4
1.2
e6/l
0.38
264
2182
134
1620
0.82
1.46
1.1
1.2
—
—
—
0
0
25
155
1.62
1.46
1.1
1.1
—
—
—
0
0
763
7093
1.09
1.45
1.9
1.9
170.1
145.7
u/l
0.35
720
6705
293
3314
0.87
1.43
1.5
1.7
—
—
—
0
0
1002
9431
1.08
1.43
1.7
1.7
—
—
—
0
0
9
40
2.25
1.40
1.0
1.5
—
72.4
—
0
5
27
173
1.56
1.39
1.6
1.4
—
—
—
0
0
1069
10102
1.08
1.37
3.2
2.6
28.0
27.7
u/l
0.14
1014
9646
394
3551
1.12
1.37
1.5
1.5
—
—
—
0
0
98
786
1.25
1.37
1.8
2.0
1.4
1.3
g/l
0.43
83
679
28
182
1.54
1.37
1.3
1.5
69104.9
99128.8
e6/l
0.14
14
123
35
239
1.47
1.36
1.7
2.5
1.5
1.4
e9/l
0.16
21
138
6
23
2.61
1.36
2.0
2.5
—
—
—
0
0
6
23
2.61
1.36
1.0
1.4
50.8
45.1
%
—
6
18
29
191
1.52
1.34
1.4
2.1
10.9
12.3
%
0.31
11
117
26
167
1.56
1.34
1.2
1.1
—
—
—
0
0
51
375
1.36
1.34
3.0
1.5
54.0
31.9
mg/l
0.72
36
312
733
6831
1.09
1.32
1.2
1.3
66.0
28.2
iu/ml
0.46
249
2103
41
291
1.41
1.32
1.1
1.1
1.0
1.0
ratio
0.03
12
107
51
376
1.36
1.32
3.0
1.5
30.8
38.9
mg/l
0.23
36
313
78
614
1.28
1.29
2.7
2.7
—
—
—
0
0
5
18
2.78
1.28
1.2
1.2
—
—
—
0
0
670
7195
0.92
1.27
1.6
1.6
1.4
1.3
mmol/l
0.51
550
6301
8
35
2.29
1.26
1.1
1.3
—
—
—
0
0
8
35
2.29
1.26
1.1
1.3
—
—
—
0
0
700
6528
1.09
1.25
1.3
1.3
11.2
9.0
u/ml
0.42
293
2778
156
1328
1.18
1.23
2.3
1.5
66.7
67.6
g/l
0.97
142
1216
567
5243
1.10
1.22
2.5
2.4
109.1
91.8
ug/g
0.56
436
4083
38
272
1.40
1.19
3.4
1.4
—
—
—
0
0
152
1298
1.18
1.17
4.2
2.8
—
—
—
0
0
6
127
0.47
1.16
1.5
1.1
—
—
—
0
0
134
1134
1.19
1.15
3.4
2.4
0.3
0.2
e6/l
0.14
129
1073
775
7283
1.08
1.15
1.7
1.7
1.1
0.8
mg/l
0.67
577
5324
224
2535
0.88
1.15
2.3
2.1
37.2
34.7
u/l
0.15
193
2141
20
126
1.59
1.14
1.5
1.1
—
—
—
0
0
3034
29852
1.08
1.11
3.4
3.5
5.6
5.6
mmol/l
0.80
2805
27998
191
1669
1.15
1.11
1.2
1.3
0.3
1.2
u/ml
2.10
19
129
413
3783
1.10
1.10
2.6
2.4
5.7
5.2
e6/l
0.33
226
1889
306
2760
1.12
1.09
3.4
3.1
4.6
4.5
pmol/l
0.55
269
2465
76
611
1.25
1.09
1.3
1.2
—
—
—
0
0
12
66
1.82
1.09
1.2
1.5
—
—
—
0
0
1388
13338
1.06
1.08
2.3
2.2
75.3
74.7
nmol/l
0.40
1276
12418
15
89
1.69
1.07
1.1
1.5
—
—
—
0
0
12
67
1.79
1.04
1.2
1.1
—
—
—
0
0
12
67
1.79
1.04
1.2
1.1
—
—
—
0
0
12
67
1.79
1.04
1.2
1.1
—
—
—
0
0
17
106
1.61
1.02
1.3
1.5
—
—
—
0
0
22
147
1.50
1.00
2.7
2.7
156.5
165.8
umol/l
0.07
16
83
72
583
1.24
0.99
2.1
2.2
1090.6
429.0
ug/l
0.44
63
517
11
61
1.81
0.98
4.6
2.2
—
—
—
0
0
20
295
0.68
0.96
1.3
1.6
—
—
—
0
0
67
541
1.24
0.96
1.3
1.3
—
—
—
0
0
470
4365
1.09
0.95
2.9
2.6
1035.9
802.8
ng/l
0.68
390
3505
40
523
0.76
0.94
1.7
1.5
0.5
0.6
g/l
0.48
27
392
64
517
1.24
0.92
1.3
1.5
—
—
—
0
0
403
4349
0.92
0.90
1.4
1.5
—
—
—
0
0
561
5264
1.08
0.89
1.4
1.4
600.3
622.1
titre
0.08
116
1084
6
29
2.07
0.89
1.0
1.0
—
6.2
—
0
11
554
5898
0.93
0.88
1.9
2.1
—
—
—
0
0
333
3062
1.10
0.86
1.8
1.9
395.6
377.7
nmol/l
0.87
311
2800
8
44
1.82
0.85
1.1
1.6
2.3
2.9
mmol/l
—
8
39
127
1106
1.15
0.83
1.3
1.5
0.5
0.5
nmol/l
0.09
98
946
87
737
1.18
0.81
3.5
2.6
—
—
—
0
0
129
1128
1.15
0.81
1.1
1.2
—
—
—
0
0
353
3269
1.09
0.79
1.3
1.4
—
—
—
0
0
33
430
0.77
0.79
2.2
2.7
221.4
85.0
ug/min
0.29
22
286
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
0.7
—
0
20
0
25
0.00
0.79
0.0
2.1
—
3.8
—
0
9
169
1508
1.13
0.78
7.3
5.2
1.4
1.3
mmol/l
0.58
164
1446
37
286
1.30
0.78
1.7
1.7
53.6
52.8
%
0.05
25
175
0
27
0.00
0.77
0.0
7.3
—
—
—
0
0
7
126
0.55
0.77
1.3
1.8
—
—
—
0
0
95
816
1.17
0.76
1.3
1.3
188.0
95.9
titre
—
10
75
13
197
0.66
0.75
1.0
1.0
—
—
—
0
0
8
132
0.61
0.73
1.4
1.1
—
—
—
0
0
18
253
0.71
0.71
12.7
12.8
996.4
854.0
nmol/l
0.73
18
245
258
2371
1.09
0.71
2.3
2.0
4.2
4.2
e9/l
0.12
204
1976
324
3008
1.08
0.71
1.4
1.3
—
—
—
0
0
59
490
1.21
0.70
1.1
1.1
—
—
—
0
0
170
1532
1.11
0.69
1.2
1.2
9.0
10.0
u/l
0.51
146
1280
17
118
1.44
0.69
1.7
2.7
55.2
48.0
%
—
6
47
5
27
1.85
0.68
1.0
1.1
1.6
1.4
umol/24h
—
5
27
22
161
1.37
0.68
2.1
2.8
—
—
—
0
0
19
260
0.73
0.66
16.4
18.5
1656.4
1507.5
nmol/l
0.46
19
252
13
86
1.51
0.66
10.2
2.1
10.3
9.2
mmol/l
—
7
65
11
70
1.57
0.65
1.4
1.6
—
—
—
0
0
10
62
1.61
0.65
1.1
1.1
—
288.0
—
0
5
584
5560
1.06
0.64
1.4
1.4
21.2
21.3
nmol/l
0.10
503
4918
22
165
1.34
0.60
2.0
2.9
771.0
886.3
e6/l
0.34
11
77
135
1498
0.90
0.59
1.6
1.6
—
—
—
0
0
678
6497
1.05
0.59
2.4
1.9
4987.8
3282.6
umol/l
0.49
595
5747
10
64
1.56
0.58
2.5
4.6
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
0.2
—
0
8
289
2703
1.07
0.56
1.2
1.3
240.5
170.3
u/ml
0.52
262
2504
11
73
1.51
0.56
1.1
1.1
—
—
—
0
0
8
55
1.46
0.56
2.5
2.6
—
—
—
0
0
25
194
1.29
0.55
3.4
3.4
0.8
0.8
nmol/l
0.19
19
152
25
194
1.29
0.55
1.0
1.1
15.5
6.1
u/ml
—
5
38
26
203
1.28
0.55
1.6
1.6
36.0
40.3
%
0.25
16
115
10
148
0.67
0.55
1.1
1.1
—
—
—
0
0
2706
26733
1.04
0.54
4.0
4.2
36.8
37.4
mmol/mol
4.20
2515
25291
6
38
1.58
0.54
1.0
1.2
—
—
—
0
0
9
62
1.45
0.53
1.0
1.0
—
—
—
0
0
23
178
1.29
0.53
2.5
2.9
12.8
64.6
mg/l
0.83
13
118
552
5764
0.95
0.52
3.2
3.3
617.6
363.3
mg/l
0.49
357
3500
94
837
1.13
0.51
7.4
3.8
23.9
24.1
mmol/l
0.26
79
725
80
705
1.14
0.51
1.3
1.3
—
—
—
0
0
18
135
1.33
0.51
2.2
2.0
1.5
1.1
ug/l
0.27
18
125
780
7539
1.04
0.49
3.4
3.3
—
—
—
0
0
741
7155
1.04
0.49
3.4
3.2
7.3
7.4
mmol/l
0.20
632
6195
169
1558
1.09
0.49
1.1
1.2
4.8
3.1
ug/l
0.45
160
1480
1319
12883
1.04
0.49
2.2
2.2
—
—
—
0
0
107
1185
0.90
0.48
2.4
2.1
103.0
4.1
iu/l
0.50
55
481
17
223
0.76
0.48
1.4
1.4
11.9
9.9
umol/l
0.46
17
209
32
262
1.22
0.48
1.2
1.1
—
—
—
0
0
145
1329
1.09
0.48
1.9
2.0
10.4
5.1
ug/l
0.50
133
1150
206
1918
1.08
0.47
1.1
1.1
—
—
—
0
0
10
68
1.47
0.47
1.4
1.8
—
—
—
0
0
14
103
1.36
0.45
1.1
1.2
—
—
—
0
0
35
292
1.20
0.45
1.3
1.2
—
—
—
0
0
7
50
1.40
0.45
1.3
1.7
—
—
—
0
0
68
768
0.88
0.44
1.9
2.0
—
—
—
0
0
162
1502
1.08
0.43
1.5
1.8
—
—
—
0
0
54
617
0.87
0.42
1.3
1.2
—
—
—
0
0
6
92
0.65
0.42
1.2
1.2
—
—
—
0
0
6
95
0.63
0.42
1.0
1.2
—
—
—
0
0
30
249
1.21
0.41
1.1
1.1
1681.9
1467.3
miu/ml
0.36
30
249
5
33
1.52
0.41
1.8
3.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.0
—
0
11
28
231
1.21
0.41
1.3
1.4
—
—
—
0
0
28
231
1.21
0.41
1.3
1.4
—
—
—
0
0
28
231
1.21
0.41
1.3
1.4
—
—
—
0
0
28
231
1.21
0.41
1.3
1.4
—
—
—
0
0
90
814
1.11
0.41
1.3
1.2
938.0
1149.3
titre
—
5
46
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
0.1
—
0
11
142
1314
1.08
0.40
2.3
2.7
163.4
126.2
ng/l
0.58
124
1160
970
9459
1.03
0.40
1.3
1.3
1.6
1.6
u/ml
0.01
315
2824
11
149
0.74
0.40
1.2
1.6
123.9
125.6
nmol/l
0.04
11
149
8
61
1.31
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
4.8
—
0
8
0
19
0.00
0.39
0.0
1.6
—
23.2
—
0
19
112
1029
1.09
0.38
1.2
1.3
—
—
—
0
0
712
6914
1.04
0.37
6.0
4.8
—
—
—
0
0
1079
10558
1.03
0.36
1.7
1.8
97.0
99.6
pmol/l
0.93
573
5587
10
135
0.74
0.36
1.8
1.6
—
—
—
0
0
5
76
0.66
0.35
1.2
1.1
—
—
—
0
0
5
78
0.64
0.35
1.2
1.5
—
—
—
0
0
117
1264
0.92
0.35
1.1
1.1
2.0
5.0
u/ml
1.73
17
204
6
42
1.43
0.35
1.8
1.8
—
—
—
0
0
86
784
1.10
0.35
2.0
2.1
12.8
13.1
%
2.18
86
774
10
134
0.75
0.34
1.0
1.1
6.8
5.6
nmol/l
—
10
126
29
341
0.85
0.34
1.3
1.3
—
—
—
0
0
36
311
1.16
0.34
2.6
3.3
—
—
—
0
0
6
86
0.70
0.33
1.0
1.1
—
4.1
—
0
17
13
101
1.29
0.31
1.0
1.1
—
—
—
0
0
30
347
0.86
0.30
1.5
1.4
7.5
6.3
g/l
0.48
21
239
17
138
1.23
0.30
1.2
1.2
23.4
15.7
pmol/l
1.35
17
125
40
353
1.13
0.30
1.3
1.3
—
—
—
0
0
30
346
0.87
0.29
1.5
1.4
0.4
0.4
g/l
0.16
21
236
30
346
0.87
0.29
1.5
1.4
2.6
2.9
g/l
0.77
21
234
8
107
0.75
0.29
2.1
2.4
166.1
164.3
nmol/l
—
8
92
17
206
0.82
0.29
1.5
1.4
—
—
—
0
0
8
108
0.74
0.29
2.6
1.8
—
—
—
0
0
11
85
1.29
0.28
1.0
1.0
—
—
—
0
0
11
85
1.29
0.28
1.0
1.0
—
—
—
0
0
11
85
1.29
0.28
1.0
1.0
—
—
—
0
0
63
689
0.91
0.27
1.1
1.1
1.2
3.0
u/ml
3.40
37
380
8
64
1.25
0.27
1.6
1.1
—
—
—
0
0
8
64
1.25
0.27
1.0
1.1
—
—
—
0
0
55
604
0.91
0.26
3.0
3.4
35.9
23.1
mg/l
0.73
24
374
20
169
1.18
0.25
1.1
1.1
—
—
—
0
0
75
694
1.08
0.25
1.3
1.3
—
—
—
0
0
267
2773
0.96
0.25
1.6
1.6
311.2
305.7
mu/l
0.06
237
2452
13
105
1.24
0.24
1.0
1.1
—
2.1
%
—
0
11
98
918
1.07
0.24
1.4
1.6
—
—
—
0
0
80
744
1.08
0.24
1.2
1.3
83.2
6612.6
e6/l
0.74
66
618
80
744
1.08
0.24
1.2
1.3
159.0
15.8
e6/l
0.47
64
586
9
77
1.17
0.24
1.1
1.1
—
—
—
0
0
90
962
0.93
0.24
1.1
1.1
—
—
—
0
0
22
189
1.16
0.24
2.7
2.6
—
—
—
0
0
794
7789
1.02
0.24
1.4
1.3
2.2
2.1
g/l
0.36
509
4949
80
745
1.08
0.24
1.3
1.2
—
—
—
0
0
14
115
1.22
0.23
1.5
1.9
1735.7
2001.9
ml
0.54
14
106
16
134
1.19
0.22
1.0
1.1
—
—
—
0
0
7
92
0.76
0.22
1.0
1.1
—
—
—
0
0
167
1597
1.05
0.22
3.3
3.3
82.0
77.2
ng/l
0.25
151
1394
31
276
1.12
0.22
1.5
1.6
5.5
5.7
mmol/l
0.13
24
217
24
210
1.14
0.21
1.1
1.1
—
—
—
0
0
28
248
1.13
0.21
1.9
1.8
5.1
25.2
u/ml
0.51
22
189
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.3
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.8
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
102.4
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
20
173
1.16
0.20
2.8
2.7
—
—
—
0
0
55
508
1.08
0.20
1.5
1.7
6715.0
8446.2
e6/l
0.33
43
372
3175
31877
0.98
0.20
11.1
10.1
39.3
39.5
%
0.92
2488
26051
220
2122
1.04
0.20
8.0
14.6
1.2
1.1
inr
0.25
47
371
28
249
1.13
0.20
1.1
1.1
—
—
—
0
0
22
193
1.14
0.19
1.1
1.1
—
—
—
0
0
2982
29687
1.02
0.19
3.0
3.1
1.2
1.2
mmol/l
1.45
2792
28111
52
481
1.08
0.19
2.0
1.3
38.0
38.8
g/l
0.42
44
422
85
803
1.06
0.18
3.1
2.5
0.4
0.4
g/l
0.01
29
266
28
310
0.90
0.17
1.2
1.2
0.1
0.9
u/ml
—
9
103
1882
18961
0.99
0.17
2.9
3.0
73.9
60.2
ug/l
3.16
1754
17984
16
184
0.87
0.17
1.1
1.2
—
—
—
0
0
33
361
0.91
0.17
9.4
3.1
—
—
—
0
0
5
69
0.72
0.17
1.0
1.1
—
—
—
0
0
106
1109
0.95
0.16
1.1
1.1
1.0
1.3
u/ml
0.15
39
413
36
331
1.09
0.16
1.6
1.4
353.4
362.6
pmol/l
0.06
28
255
413
4047
1.02
0.16
2.7
2.8
105.4
312.2
ng/l
2.04
196
2111
11
130
0.85
0.16
2.5
2.5
44.2
49.5
umol/l
0.25
11
113
47
504
0.93
0.16
1.2
1.3
—
57.4
—
0
30
8
73
1.10
0.15
2.6
2.4
—
—
—
0
0
38
351
1.08
0.15
1.0
1.1
0.4
2.0
u/ml
—
9
103
324
3314
0.98
0.15
1.1
1.2
—
—
—
0
0
73
692
1.06
0.15
1.2
1.3
349.8
325.1
ug/g
0.37
41
330
23
207
1.11
0.15
2.1
2.7
—
—
—
0
0
41
381
1.08
0.14
1.2
1.1
—
0.4
nmol/l
—
0
13
7
86
0.81
0.14
1.3
1.2
—
—
—
0
0
39
362
1.08
0.14
1.1
1.1
193.7
204.1
mg/l
0.25
31
317
64
675
0.95
0.14
1.2
1.3
1.3
1.4
nmol/l
0.38
51
564
393
3857
1.02
0.14
1.2
1.2
166.1
155.6
iu/ml
0.19
150
1550
234
2282
1.03
0.13
1.4
1.3
228.1
240.6
miu/ml
0.24
126
1195
29
315
0.92
0.13
1.0
1.0
—
—
—
0
0
28
304
0.92
0.13
1.3
1.1
—
—
—
0
0
209
2143
0.97
0.12
2.9
2.7
—
—
—
0
0
11
95
1.16
0.11
1.0
1.2
—
—
—
0
0
11
95
1.16
0.11
1.3
2.3
221.7
148.4
e6/l
—
6
56
68
711
0.96
0.11
1.2
1.2
—
—
—
0
0
32
343
0.93
0.11
1.5
1.4
—
—
—
0
0
10
86
1.16
0.11
1.3
1.2
—
—
—
0
0
72
750
0.96
0.11
2.6
2.6
—
—
—
0
0
21
192
1.09
0.10
2.4
2.8
—
22.6
—
0
5
51
536
0.95
0.10
1.0
1.0
—
—
—
0
0
16
177
0.90
0.10
2.3
2.9
—
—
—
0
0
23
212
1.09
0.10
2.9
2.8
—
—
—
0
0
343
3483
0.98
0.10
1.3
1.4
—
—
—
0
0
598
5915
1.01
0.10
1.4
1.5
—
—
—
0
0
238
2425
0.98
0.10
1.2
1.2
—
—
—
0
0
45
428
1.05
0.09
1.4
1.6
—
—
—
0
0
40
379
1.06
0.09
1.1
1.1
36.5
35.3
mg/l
0.07
28
313
71
684
1.04
0.09
1.1
1.1
9.4
11.8
au/ml
—
8
45
96
931
1.03
0.09
1.1
1.1
1.7
1.4
u/ml
0.13
16
241
3085
30915
0.99
0.09
3.2
3.4
1.6
1.6
mmol/l
0.07
2904
29367
25
233
1.07
0.09
1.5
3.0
—
—
—
0
0
117
1200
0.97
0.08
2.4
2.3
—
—
—
0
0
6
58
1.03
0.08
1.3
1.2
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
119
1161
1.03
0.08
2.1
1.9
1.1
1.2
g/l
0.52
110
1096
320
3158
1.01
0.08
1.3
1.3
—
—
—
0
0
101
985
1.03
0.07
7.3
7.2
—
—
—
0
0
81
833
0.97
0.07
1.0
1.1
6.2
4.5
u/ml
0.18
26
320
9
84
1.07
0.07
5.3
2.5
—
—
—
0
0
9
85
1.06
0.07
1.7
2.6
—
—
—
0
0
13
118
1.10
0.07
3.4
3.3
—
—
—
0
0
10
89
1.12
0.06
2.0
1.6
—
—
—
0
0
69
670
1.03
0.06
1.0
1.1
0.0
0.4
u/ml
—
8
138
83
809
1.03
0.06
1.1
1.1
—
—
—
0
0
19
203
0.94
0.06
1.7
2.1
2.6
2.3
u/field
—
8
98
287
2902
0.99
0.06
1.3
1.3
—
—
—
0
0
34
355
0.96
0.06
1.3
1.5
—
—
—
0
0
83
811
1.02
0.05
1.1
1.1
—
—
—
0
0
32
334
0.96
0.05
1.2
1.1
—
—
—
0
0
15
161
0.93
0.05
1.2
1.1
—
—
—
0
0
10
110
0.91
0.05
2.7
2.2
14.4
15.4
umol/l
—
10
110
41
424
0.97
0.05
1.5
1.3
—
—
—
0
0
21
199
1.06
0.04
1.5
1.5
1.6
1.5
nmol/l
0.38
21
178
79
774
1.02
0.04
1.1
1.1
3.8
4.4
u/ml
0.17
25
316
392
3892
1.01
0.04
1.2
1.2
—
—
—
0
0
115
1132
1.02
0.04
1.2
1.3
57.0
39.6
u/ml
—
8
79
237
2351
1.01
0.03
1.2
1.3
34.7
33.7
au/ml
—
5
93
149
1474
1.01
0.03
1.7
1.7
—
—
—
0
0
598
6004
1.00
0.03
3.9
4.0
9.5
11.3
mg/mmol
0.42
374
3747
26
251
1.04
0.02
1.2
1.2
—
—
—
0
0
16
152
1.05
0.02
1.3
1.6
1.1
3.2
u/field
—
8
107
100
1009
0.99
0.01
1.2
1.3
11.5
6.3
u/ml
0.31
12
97
102
1029
0.99
0.01
1.2
1.1
—
—
—
0
0
115
1141
1.01
0.01
1.6
1.8
20.8
20.5
s
0.35
89
921
137
1379
0.99
0.01
2.1
2.2
4.4
4.9
umol/l
0.42
98
1017
38
373
1.02
0.01
1.2
1.3
—
—
—
0
0
114
1132
1.01
0.01
2.2
1.9
0.2
0.2
g/l
0.19
106
1067
253
2539
1.00
0.01
2.2
2.3
21.1
21.7
au/ml
0.03
18
191
97
977
0.99
0.01
1.1
1.1
7.9
5.2
u/ml
0.48
40
520
103
1023
1.01
0.00
1.3
1.3
12.3
8.9
u/ml
0.17
15
174
3108
31071
1.00
0.00
3.3
3.4
4.8
4.8
mmol/l
0.25
2933
29568
24
234
1.03
0.00
1.1
1.0
319.3
298.6
mg/l
0.80
24
213
35
356
0.98
0.00
1.2
1.4
—
—
—
0
0
48
474
1.01
0.00
4.3
2.5
0.9
0.8
nmol/l
0.38
41
398
32
322
0.99
0.00
1.4
1.6
5.5
5.1
mmol/l
1.43
32
308
17
165
1.03
0.00
1.2
1.2
—
—
—
0
0
28
275
1.02
0.00
1.0
1.1
8.2
8.8
iu/ml
—
6
67
92
922
1.00
0.00
1.0
1.1
2.5
0.9
u/ml
0.52
29
379
3135
31355
1.00
0.00
3.5
3.7
2.9
2.9
mmol/l
0.96
2934
29645
10
101
0.99
0.00
1.0
1.1
—
—
—
0
0
26
261
1.00
0.00
1.1
1.2
—
—
—
0
0
36
359
1.00
0.00
1.0
1.0
1.9
0.8
u/ml
—
7
81
11
106
1.04
0.00
1.0
1.1
—
4.3
iu/ml
—
0
10
16
164
0.98
0.00
1.3
1.2
—
—
—
0
0
32
317
1.01
0.00
1.2
1.6
—
—
—
0
0
56
563
0.99
0.00
1.1
1.2
58.4
18479.0
iu/ml
0.64
21
145
13
133
0.98
0.00
2.6
2.4
11.3
10.7
%
0.25
13
133
24
237
1.01
0.00
1.6
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
220.0
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
52
0.96
0.00
1.0
1.3
280.2
330.7
pmol/l
—
5
33
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
5
52
0.96
0.00
1.0
1.2
102.4
85.0
ng/l
—
5
52
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
5.2
6.0
—
—
—
0
0
5
56
0.89
0.00
1.4
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
2.6
—
0
8
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
1281.4
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
22
220
1.00
0.00
2.3
2.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_INSITU_CERVIX_UTERI_EXALLC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_INSITU_CERVIX_UTERI_EXALLC 1.416 [1.21, 1.65] < 0.001
Birth year 0.994 [0.99, 1.0] 0.175

During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 3908 females with CD2_INSITU_CERVIX_UTERI_EXALLC died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_CERVIX_UTERI_EXALLC.

N-year risk Females Males
1 0.151% No data
5 0.802% No data
10 1.94% No data
15 3.761% No data
20 6.487% No data

Relationships between endpoints

Index endpoint: CD2_INSITU_CERVIX_UTERI_EXALLC – Carcinoma in situ of cervix uteri

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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