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Leukaemia of unspecified cell type

CD2_LEUKAEMIA_NAS

leukemia: A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C95
  • Hospital discharge: ICD-9 20[7-8]
  • Hospital discharge: ICD-8 207
  • Hospital discharge: excluded ICD-9 207[0-8]
  • Hospital discharge: excluded ICD-8 207[0-2]
  • Cause of death: ICD-10 C95
  • Cause of death: ICD-9 20[7-8]
  • Cause of death: ICD-8 207
  • Cause of death: excluded ICD-9 207[0-8]
  • Cause of death: excluded ICD-8 207[0-2]

2 out of 7 registries used, show all original rules.

303

4. Check minimum number of events

None

303

5. Include endpoints

None

303

6. Filter based on genotype QC (FinnGen only)

303

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF8
Parent code in ICD-10
C81-C96
Name in latin
Leuc(h)aemiae typo cellulari non specificato

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 303 132 171
Unadjusted period prevalence (%) 0.06 0.04 0.08
Median age at first event (years) 62.58 56.99 66.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
298
Matched controls
2982
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
211.5
177
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
104.8
182.1
193
51
XW000
NOMESCO Finland
Bone marrow biopsy
63.3
134.1
155
50
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
388.0
125.5
118
5
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
93.8
85
*
WW500
NOMESCO Finland
Blood transfusion
27.0
69.4
98
53
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
26.5
63.0
89
47
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
186.8
59.3
60
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
335.6
56.2
55
*
127
Kela drug reimbursment
Transplant complication
54.6
46.0
54
12
L03AA02
ATC
filgrastim; parenteral
27.2
45.5
63
29
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
114.0
45.3
48
5
A05AA02
ATC
ursodeoxycholic acid; oral
45.7
43.6
53
14
J05AB11
ATC
valaciclovir; oral
8.5
41.0
100
167
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.1
40.2
114
238
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
11.6
40.1
79
90
A04AA01
ATC
ondansetron; systemic, rectal
11.8
38.1
74
81
L01BB02
ATC
mercaptopurine; oral
62.5
37.5
43
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.2
36.3
72
82
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
373.6
33.6
33
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
184.7
32.4
33
*
ZX120
NOMESCO Finland
Intravenous
7.0
30.0
81
150
M04AA01
ATC
allopurinol; systemic
5.9
29.9
96
223
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
26.2
29.7
41
18
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
28.6
27
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
296.3
27.2
27
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
41.0
26.8
33
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
26.5
101
281
R50.9
ICD-10 Finland
Fever, unspecified
5.2
26.3
93
238
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
283.8
26.1
26
*
L04AD01
ATC
ciclosporin; systemic
31.7
26.0
34
12
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
13.7
25.2
44
37
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
61.5
24.5
28
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.6
23.4
75
169
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
23.3
179
898
WW200
NOMESCO Finland
Immunization
16.7
23.2
37
25
L01XX05
ATC
hydroxycarbamide; oral
27.9
20.8
28
11
TAB00
NOMESCO Finland
Lumbar puncture
9.8
20.5
42
49
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.4
20.4
46
63
121
Kela drug reimbursment
Severe hypofunction of sexual glands
22.8
20.4
29
14
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
43.3
19.8
24
6
J02AC03
ATC
voriconazole; systemic
213.5
19.8
20
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.2
19.8
42
52
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
17.4
19.2
30
19
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
106.8
18.8
20
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.1
17.0
48
91
D64.9
ICD-10 Finland
Anaemia, unspecified
4.5
16.3
63
169
J01MA12
ATC
levofloxacin; systemic
3.5
16.3
90
329
189
Kela drug reimbursment
Imatinib
50.5
16.2
19
*
L01XE01
ATC
[U] imatinib; oral
63.6
15.9
18
*
H02AB09
ATC
hydrocortisone; systemic
10.0
15.1
30
33
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.3
14.9
36
55
B73
ICPC
Leukaemia
84.3
14.7
16
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
14.7
14
*
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
14.7
14
*
JN4BD
NOMESCO Finland
Extensive body CT
4.0
14.3
62
184
D70.89
ICD-10 Finland
Neutropenic splenomegaly
25.2
14.0
19
8
A41.9
ICD-10 Finland
Sepsis, unspecified
6.8
13.8
35
57
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
13.6
13
*
J02AC04
ATC
posaconazole; systemic
+∞
13.6
13
*
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
146.3
13.6
14
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.3
12.7
34
60
Z85.6
ICD-10 Finland
Personal history of leukaemia
135.4
12.5
13
*
L04AA06
ATC
mycophenolic acid; systemic
15.2
12.5
20
14
TPH00
NOMESCO Finland
Phlebotomy
48.7
12.0
14
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.5
11.6
27
39
9801/3-C42.1
ICD-O-3
Acute leukemia, NOS, of bone marrow
+∞
11.5
11
*
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
+∞
11.5
11
*
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
+∞
11.5
11
*
2AX04
NOMESCO Finland
NA
124.6
11.5
12
*
ZX131
NOMESCO Finland
Intrathecal
124.6
11.5
12
*
H02AB02
ATC
dexamethasone; systemic
3.6
11.4
55
178
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
17.9
11.3
17
10
ZX090
NOMESCO Finland
Other technic of radiotherapy
8.6
11.3
24
30
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
45.1
11.0
13
*
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
45.1
11.0
13
*
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
9.4
11.0
22
25
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
62.3
10.7
12
*
1DB06
NOMESCO Finland
NA
+∞
10.5
10
*
2089X
ICD-9 Finland
Leukaemia of unspecified cell type, Unspecified leukaemia
+∞
10.5
10
*
152
Kela drug reimbursment
Nilotinib
+∞
10.5
10
*
ZX108
NOMESCO Finland
Inhalation
33.8
10.4
13
*
ZX121
NOMESCO Finland
Central venous catheter
19.6
10.4
15
8
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.7
10.3
82
371
J01MA14
ATC
moxifloxacin; systemic
3.8
10.2
44
130
J05AB01
ATC
aciclovir; systemic
2.7
10.0
80
362
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
9.6
111
607
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
9.4
9
*
H02AB04
ATC
methylprednisolone; systemic
3.1
9.4
56
209
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.0
129
771
N02AA05
ATC
oxycodone; systemic
2.8
8.8
60
245
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
14.6
8.8
14
10
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
51.5
8.7
10
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
28.4
8.5
11
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
92.5
8.5
9
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
8.4
8
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
34.4
8.1
10
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.5
8.1
15
15
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
8.0
89
468
A07AA02
ATC
nystatin; oral
4.0
7.8
31
85
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.2
7.8
40
136
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
46.2
7.8
9
*
J02AC01
ATC
fluconazole; systemic
2.1
7.7
110
648
150
Kela drug reimbursment
Dasatinib
82.0
7.4
8
*
2AA01
NOMESCO Finland
NA
82.0
7.4
8
*
L01XE06
ATC
[U] dasatinib; systemic
82.0
7.4
8
*
5BA08
NOMESCO Finland
NA
13.8
7.4
12
9
A41.8
ICD-10 Finland
Other specified sepsis
8.7
7.4
15
18
212
Kela drug reimbursment
Gout
7.1
7.4
17
25
L01XE08
ATC
[U] nilotinib; oral
+∞
7.3
7
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
7.3
35
113
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.9
7.2
19
34
ZX114
NOMESCO Finland
Intramuscular
8.2
7.2
15
19
TPX15
NOMESCO Finland
Removal of vascular injection port
30.8
7.2
9
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
20.6
7.2
10
5
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.5
6.9
31
95
N05BA06
ATC
lorazepam; systemic, sublingual
3.8
6.9
28
79
Z51.5
ICD-10 Finland
Palliative care
3.6
6.9
30
90
316
Kela drug reimbursment
Imatinib
41.0
6.8
8
*
ZX112
NOMESCO Finland
Subcutaneous
6.1
6.7
17
29
1XC02
NOMESCO Finland
NA
23.1
6.7
9
*
C90.0
ICD-10 Finland
Multiple myeloma
9.0
6.6
13
15
WA010
NOMESCO Finland
Adjuvant whole body radiotherapy
71.3
6.4
7
*
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
71.3
6.4
7
*
1XX02
NOMESCO Finland
NA
71.3
6.4
7
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
11.4
6.3
11
10
L04AA01
ATC
[U] ciclosporin; systemic
7.3
6.3
14
20
L01EA03
ATC
nilotinib; oral
+∞
6.3
6
*
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
+∞
6.3
6
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
6.3
6
*
1CX01
NOMESCO Finland
NA
+∞
6.3
6
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
5AD01
NOMESCO Finland
NA
+∞
6.3
6
*
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.9
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
71
20
46.06
116.40
1.3
1.3
—
—
—
0
0
74
26
37.34
113.83
1.2
1.1
—
—
—
0
0
86
46
25.71
113.42
5.8
1.5
—
—
—
0
0
71
22
41.84
113.34
2.6
2.5
—
—
—
0
0
77
51
19.90
91.22
1.4
1.3
—
—
—
0
0
74
47
20.51
89.42
1.5
1.3
100.7
103.7
u/ml
—
21
7
75
53
18.48
85.75
1.3
1.2
247.8
257.6
u/ml
0.05
48
25
87
82
14.48
84.27
1.3
1.3
—
—
—
0
0
60
32
23.13
78.17
1.2
1.1
—
—
—
0
0
135
300
7.31
63.96
9.7
3.2
1.6
1.7
%
0.27
126
269
48
25
22.63
62.77
1.8
1.4
—
—
—
0
0
113
218
7.67
61.17
8.0
3.1
59.9
68.2
e9/l
1.23
90
174
98
178
7.66
55.72
9.7
3.8
1.2
0.9
%
0.74
57
59
50
37
15.99
54.94
1.2
1.1
—
—
—
0
0
132
349
5.93
50.46
13.2
3.9
0.8
0.8
mmol/l
0.85
125
328
44
32
15.92
48.64
8.8
3.7
1.1
1.4
%
0.21
36
26
83
147
7.40
47.81
1.4
1.5
—
—
—
0
0
84
158
6.97
45.54
9.0
3.9
0.7
0.5
%
0.76
35
39
105
252
5.85
44.03
1.6
1.6
—
—
—
0
0
41
32
14.66
43.44
8.7
4.1
—
—
—
0
0
119
323
5.42
43.28
16.8
5.8
1.1
1.1
mmol/l
0.31
114
295
82
164
6.48
41.56
10.1
4.0
1.0
0.2
%
0.59
55
52
38
28
15.37
41.53
2.1
1.6
—
—
—
0
0
38
28
15.37
41.53
2.1
1.6
—
—
—
0
0
38
28
15.37
41.53
2.1
1.6
—
—
—
0
0
38
28
15.37
41.53
2.1
1.6
—
—
—
0
0
110
303
5.13
38.82
1.6
1.7
—
—
—
0
0
34
24
15.83
37.95
5.4
2.1
314.8
548.3
e6/l
—
13
9
76
159
6.05
36.46
9.3
3.9
8.7
0.2
%
1.79
41
47
61
112
6.57
33.30
1.7
2.2
1.7
1.5
g/l
0.43
45
97
31
25
13.70
31.99
7.7
2.8
51.8
59.9
%
0.58
20
17
37
40
10.40
31.57
7.8
1.2
—
—
—
0
0
31
26
13.17
31.23
6.5
2.3
1.2
1.3
e9/l
0.11
18
14
34
5
76.20
30.59
1.0
1.0
—
—
—
0
0
34
5
76.20
30.59
1.4
1.2
—
—
—
0
0
79
202
4.94
29.80
3.7
2.9
63.7
66.1
g/l
1.71
74
183
147
596
3.85
29.53
10.6
2.7
307.0
5370.0
umol/l
2.25
142
513
175
800
3.81
29.24
26.8
5.7
—
—
—
0
0
26
19
14.87
28.28
5.0
2.6
10.1
9.4
%
0.09
12
12
110
380
3.97
27.67
1.6
1.9
—
—
—
0
0
37
50
8.29
26.48
7.9
1.2
1.5
3.0
e6/l
1.10
26
38
37
50
8.29
26.48
7.9
1.3
6.3
682.0
e6/l
0.96
27
39
30
6
55.25
25.76
4.0
1.2
—
—
—
0
0
24
20
12.95
24.13
1.6
2.6
34.4
48.5
%
—
7
7
146
665
3.31
23.16
14.9
4.0
—
—
—
0
0
21
15
14.97
23.00
6.6
1.0
—
—
—
0
0
32
45
7.83
22.06
7.8
1.1
3.5
3.8
mmol/l
0.82
32
40
24
23
11.25
22.06
10.2
1.2
—
—
—
0
0
21
17
13.20
21.41
1.0
1.2
—
—
—
0
0
197
1106
3.23
21.25
28.7
6.0
9.7
8.7
%
1.27
191
1031
19
13
15.53
21.24
6.4
1.5
0.2
0.2
e9/l
0.19
19
13
193
1074
3.20
21.08
27.1
5.7
0.6
0.6
%
0.53
188
995
195
1100
3.17
20.64
27.5
5.6
2.2
2.8
%
5.26
190
1020
198
1134
3.15
20.26
27.9
5.8
30.2
28.0
%
1.33
192
1052
23
5
49.51
19.48
1.4
1.8
—
—
—
0
0
198
1174
2.98
18.29
24.3
5.5
0.7
0.6
e9/l
0.24
186
1001
23
7
35.38
18.24
1.2
1.0
—
—
—
0
0
198
1177
2.97
18.15
24.4
5.5
0.0
0.0
e9/l
3.89
185
1007
199
1202
2.91
17.41
24.8
5.5
2.1
1.9
e9/l
0.20
188
1057
200
1214
2.90
17.29
28.3
5.9
0.1
0.2
e9/l
4.84
186
1062
109
496
2.87
16.21
6.7
1.7
3.7
1.3
mg/l
1.34
96
388
212
1368
2.83
15.58
46.5
9.2
3.2
4.2
e9/l
1.53
200
1184
135
702
2.66
15.31
12.2
2.4
—
—
—
0
0
104
478
2.79
15.01
14.0
4.8
—
—
—
0
0
53
164
3.70
14.92
2.6
2.5
—
—
—
0
0
167
982
2.56
14.44
16.9
4.9
33.5
35.4
g/l
4.24
162
920
177
1076
2.55
14.16
20.9
6.3
1.2
1.2
mmol/l
1.09
168
974
132
703
2.56
13.97
13.0
4.0
7.4
7.4
ph
0.63
24
127
108
522
2.66
13.97
11.1
2.3
—
—
—
0
0
169
1026
2.46
13.27
15.0
4.2
—
—
—
0
0
186
1192
2.45
12.76
23.8
7.2
1.2
1.2
mmol/l
0.75
161
1012
65
262
2.89
11.73
1.8
1.6
—
—
—
0
0
14
6
24.36
10.33
3.8
1.7
—
—
—
0
0
14
6
24.36
10.33
3.8
1.7
10.0
6.0
%
—
14
6
152
954
2.19
10.15
4.6
2.8
535.3
128.2
ug/l
6.70
143
872
105
576
2.26
9.71
1.9
2.2
3.2
3.0
mg/l
0.40
91
499
13
6
22.54
9.43
1.9
1.5
—
—
—
0
0
93
499
2.25
8.97
2.1
1.4
1.8
2.6
g/l
4.08
81
282
17
32
5.57
8.79
4.7
1.6
35.4
32.3
pg
2.56
17
32
12
6
20.74
8.53
9.1
6.3
39.5
56.3
%
—
12
6
117
703
2.08
8.36
5.1
2.6
52.2
56.6
u/l
0.85
112
647
143
925
2.03
8.34
13.3
9.5
1.3
1.3
inr
0.35
40
263
12
7
17.78
8.14
1.0
1.0
—
—
—
0
0
68
333
2.34
8.05
2.3
2.6
31.2
22.6
%
1.69
59
283
103
598
2.09
8.00
2.3
1.4
—
—
—
0
0
103
608
2.05
7.59
36.9
7.0
—
—
—
0
0
7
0
+∞
7.32
1.9
0.0
13.7
—
%
—
7
0
21
58
3.82
6.88
2.6
1.8
—
—
—
0
0
13
24
5.61
6.83
1.2
1.2
—
—
—
0
0
116
748
1.89
6.43
5.7
3.4
2.3
2.4
mmol/l
3.52
109
654
19
54
3.69
5.98
5.8
3.5
—
—
—
0
0
16
41
4.06
5.79
9.3
3.1
47.6
57.4
%
1.04
16
41
35
148
2.54
5.64
6.7
3.5
—
—
—
0
0
11
21
5.40
5.56
1.0
1.1
—
—
—
0
0
8
5
16.37
5.44
1.0
1.0
—
—
—
0
0
39
177
2.38
5.41
1.3
1.8
—
—
—
0
0
143
1046
1.70
4.82
36.3
9.5
0.0
0.0
e9/l
0.56
124
843
60
344
1.93
4.58
2.0
1.9
—
—
—
0
0
42
212
2.14
4.54
12.6
4.3
—
—
—
0
0
51
280
1.99
4.41
3.8
1.5
—
—
—
0
0
73
452
1.81
4.38
1.9
1.7
1203.6
1156.1
nmol/l
0.17
64
344
33
154
2.28
4.31
3.5
2.7
3.4
4.0
e9/l
0.41
28
118
40
203
2.12
4.26
1.6
1.4
—
—
—
0
0
45
242
2.01
4.11
11.3
9.4
94.7
95.4
%
0.28
40
233
48
267
1.95
3.99
10.8
8.9
1.6
1.0
mmol/l
0.55
34
211
189
1535
1.61
3.89
5.5
4.6
26.0
2651.7
e6/l
—
5
27
8
11
7.43
3.88
1.5
1.2
—
—
—
0
0
45
248
1.96
3.84
21.4
4.5
—
—
—
0
0
124
916
1.60
3.78
2.0
2.0
87.9
94.0
pmol/l
0.90
84
469
6
5
12.20
3.78
1.7
2.2
—
—
—
0
0
17
63
2.80
3.55
2.4
2.0
9.4
7.6
u/l
0.28
11
54
6
6
10.17
3.51
1.2
1.0
—
—
—
0
0
9
18
5.12
3.39
1.2
1.9
—
—
—
0
0
43
244
1.89
3.37
22.3
4.3
2.0
1.8
mmol/l
0.24
34
180
32
165
2.05
3.29
10.5
6.8
—
—
—
0
0
19
79
2.50
3.20
33.1
5.0
1.2
1.6
mg/l
1.87
19
72
74
503
1.62
3.09
3.9
2.7
4.2
4.6
e6/l
0.22
69
444
6
8
7.62
3.07
1.2
1.1
—
—
—
0
0
44
268
1.75
2.76
10.0
8.8
4.9
5.1
kpa
0.71
39
255
71
492
1.58
2.72
3.9
2.9
574.2
565.9
mosm/kgh2o
0.11
66
414
37
215
1.82
2.71
15.4
7.5
—
—
—
0
0
7
15
4.75
2.61
1.3
1.1
—
—
—
0
0
25
130
2.01
2.54
1.6
1.2
—
—
—
0
0
43
268
1.70
2.49
10.2
8.8
10.7
11.9
kpa
1.09
38
257
95
714
1.48
2.49
4.6
3.2
—
—
—
0
0
7
16
4.45
2.49
1.1
1.2
—
—
—
0
0
32
186
1.81
2.36
3.5
3.8
—
—
—
0
0
44
281
1.66
2.34
1.2
1.3
330.0
550.2
titre
—
8
65
114
899
1.43
2.30
3.9
4.0
58.0
39.2
ng/l
0.30
88
630
200
2227
0.70
2.19
4.9
4.9
2.7
2.7
mmol/l
0.20
189
2040
7
19
3.75
2.16
1.0
1.1
—
—
—
0
0
86
651
1.45
2.14
5.5
3.2
—
—
—
0
0
96
743
1.43
2.12
5.4
3.4
41.4
134.0
e6/l
0.53
82
577
67
485
1.49
2.09
1.5
1.8
396.7
440.8
pmol/l
0.68
59
408
10
38
2.69
2.03
1.0
1.2
—
—
—
0
0
238
2559
0.67
2.01
71.8
21.2
3.9
4.5
e12/l
23.03
233
2481
17
84
2.08
2.00
8.2
3.9
—
—
—
0
0
106
845
1.39
1.96
6.0
3.9
15.5
114.6
e6/l
2.26
85
608
196
2171
0.72
1.88
4.5
4.3
1.3
1.4
mmol/l
4.25
183
1983
8
29
2.80
1.80
1.0
3.8
—
—
—
0
0
86
676
1.38
1.70
5.6
3.3
0.2
0.5
e6/l
1.37
71
506
7
25
2.84
1.66
3.7
2.7
—
—
—
0
0
7
25
2.84
1.66
1.0
1.1
212.9
239.3
pmol/l
—
7
20
62
463
1.43
1.64
5.4
3.8
71.8
224.7
ng/l
1.34
54
370
190
1690
1.33
1.62
5.5
4.1
18.9
12.0
mm/h
4.64
182
1546
70
542
1.38
1.51
3.5
3.8
—
—
—
0
0
21
125
1.73
1.48
18.0
12.5
—
—
—
0
0
7
28
2.53
1.46
1.0
1.1
49.0
25.2
mu/l
—
7
23
7
28
2.53
1.46
1.0
1.2
—
—
—
0
0
6
23
2.64
1.37
1.2
2.0
—
—
—
0
0
225
2406
0.75
1.36
35.0
13.5
—
—
—
0
0
5
18
2.81
1.29
13.4
3.1
—
—
—
0
0
14
78
1.83
1.23
8.4
3.2
—
—
—
0
0
9
169
0.52
1.23
1.2
1.4
—
—
—
0
0
5
19
2.66
1.22
15.0
5.3
—
7.4
—
0
5
13
71
1.87
1.21
1.5
1.2
—
—
—
0
0
6
26
2.33
1.19
1.7
1.3
1949.3
1858.4
e6/l
—
6
18
5
20
2.52
1.15
2.8
3.3
—
—
—
0
0
203
2183
0.79
1.14
5.1
4.4
4.4
4.6
mmol/l
1.45
193
2013
200
2154
0.79
1.13
6.0
4.5
6.0
6.0
mmol/l
0.01
187
1957
41
307
1.39
1.09
22.6
23.8
1.4
1.3
inr
—
7
39
5
21
2.40
1.09
1.0
1.4
—
—
—
0
0
5
21
2.40
1.09
1.4
1.2
—
—
—
0
0
10
52
1.95
1.07
4.3
3.1
—
—
—
0
0
190
2052
0.80
1.06
4.8
4.5
2.1
2.0
mu/l
1.32
179
1845
59
727
0.77
1.05
2.9
3.0
—
—
—
0
0
5
22
2.29
1.04
1.6
1.3
—
—
—
0
0
175
1593
1.23
1.02
6.1
4.3
—
—
—
0
0
38
286
1.38
0.99
2.4
2.3
125.4
130.0
ug/g
0.04
33
225
0
30
0.00
0.98
0.0
1.0
—
1.4
—
0
14
6
28
2.17
0.92
2.5
2.1
—
—
—
0
0
37
475
0.75
0.88
2.6
2.9
0.6
0.8
ug/l
0.99
26
297
6
30
2.02
0.87
1.0
1.1
—
—
—
0
0
195
2075
0.83
0.80
5.0
5.8
39.4
40.2
mmol/mol
0.50
183
1926
0
25
0.00
0.79
0.0
1.0
—
4.8
—
0
13
14
209
0.65
0.79
1.2
1.3
—
—
—
0
0
17
116
1.49
0.76
10.7
9.6
23.2
24.3
mmol/l
0.64
12
110
5
24
2.10
0.75
13.6
3.0
—
—
—
0
0
44
537
0.79
0.73
1.2
1.4
4.9
1.3
u/ml
—
10
137
5
25
2.02
0.73
1.8
1.3
136960.0
32343.1
e6/l
—
5
13
233
2428
0.83
0.68
37.5
10.0
30.4
26.0
u/l
2.69
227
2334
5
27
1.87
0.68
1.4
1.5
—
—
—
0
0
125
1134
1.17
0.67
3.4
3.8
0.0
0.0
estimate
0.00
18
216
99
885
1.18
0.63
2.4
2.1
—
—
—
0
0
126
1149
1.17
0.63
3.5
3.8
0.0
0.0
estimate
0.00
18
203
5
30
1.68
0.61
2.8
1.3
—
—
—
0
0
31
247
1.28
0.59
1.3
1.3
—
—
—
0
0
200
2098
0.86
0.56
51.1
15.9
35.4
40.1
%
10.55
137
1538
11
159
0.68
0.55
3.1
2.8
—
—
—
0
0
6
40
1.51
0.52
1.8
3.4
12.3
36.3
u/ml
—
6
40
123
1136
1.14
0.50
4.7
5.1
0.0
0.0
estimate
0.00
18
208
7
45
1.57
0.49
69.6
6.5
—
—
—
0
0
164
1551
1.13
0.44
5.7
4.0
—
—
—
0
0
6
91
0.65
0.43
1.7
2.8
—
—
—
0
0
17
216
0.77
0.42
1.5
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
—
—
0
0
0
17
0.00
0.41
0.0
5.4
—
—
—
0
0
10
137
0.72
0.40
1.2
1.2
81.0
112.1
iu/ml
—
5
49
28
234
1.22
0.39
1.4
1.6
—
—
—
0
0
11
80
1.39
0.39
1.4
1.1
—
—
—
0
0
69
624
1.14
0.38
3.6
4.1
0.0
0.0
estimate
0.00
19
203
10
72
1.40
0.37
3.2
2.3
24.2
24.4
mmol/l
—
10
60
58
644
0.88
0.36
2.9
3.1
1683.6
251.0
mg/l
0.66
44
427
9
125
0.71
0.36
1.8
2.4
—
—
—
0
0
62
680
0.89
0.33
3.4
3.9
11.7
9.7
mg/mmol
0.18
42
436
34
296
1.17
0.32
1.2
1.3
—
—
—
0
0
203
2095
0.91
0.32
5.4
3.9
1.5
1.3
mmol/l
3.74
192
1913
16
129
1.25
0.31
1.2
1.3
—
—
—
0
0
32
366
0.86
0.31
1.3
1.3
12.7
31.7
iu/ml
—
9
122
11
85
1.31
0.28
1.9
3.5
0.4
0.2
g/l
—
5
35
8
62
1.30
0.28
1.3
1.4
0.9
0.8
nmol/l
—
8
52
12
95
1.27
0.26
2.6
1.9
—
—
—
0
0
5
38
1.32
0.23
1.4
2.9
—
—
—
0
0
5
38
1.32
0.23
2.2
1.2
4712.8
28641.5
e6/l
—
5
24
69
646
1.09
0.22
5.2
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
6.7
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
12.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
11
89
1.24
0.21
1.3
1.2
—
—
—
0
0
5
43
1.17
0.21
1.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
50
1.20
0.20
2.3
2.1
—
—
—
0
0
17
195
0.86
0.18
1.3
1.2
—
—
—
0
0
10
121
0.82
0.18
2.4
3.8
—
—
—
0
0
59
627
0.93
0.17
2.8
3.4
—
—
—
0
0
13
111
1.18
0.16
45.0
4.0
1.4
1.2
%
0.56
13
111
7
87
0.80
0.14
1.0
1.3
—
—
—
0
0
7
87
0.80
0.14
1.0
1.3
—
—
—
0
0
7
88
0.79
0.14
1.0
1.4
—
—
—
0
0
23
212
1.09
0.10
1.4
1.5
—
—
—
0
0
27
252
1.08
0.09
3.9
4.3
3.7
64.1
ug/l
1.14
22
206
6
57
1.05
0.08
2.7
2.2
—
—
—
0
0
26
276
0.94
0.08
1.8
1.3
—
—
—
0
0
6
71
0.84
0.07
1.0
1.3
—
4.4
—
0
6
6
72
0.83
0.07
1.0
1.4
—
—
—
0
0
7
83
0.84
0.07
1.0
1.3
—
—
—
0
0
234
2324
1.03
0.05
53.6
14.7
26.8
25.0
mg/l
0.29
222
1809
16
150
1.07
0.04
2.4
2.5
—
14.9
—
0
6
17
179
0.95
0.03
2.8
4.2
93.3
82.2
ng/l
0.38
17
157
69
700
0.98
0.02
2.6
3.0
6.5
7.7
mmol/l
1.28
62
589
169
1700
0.99
0.02
4.1
3.7
14.9
14.8
pmol/l
0.27
156
1508
19
183
1.04
0.01
4.1
3.9
—
—
—
0
0
36
353
1.02
0.01
1.2
1.3
3.3
10.9
u/ml
1.49
13
133
14
134
1.05
0.00
1.3
1.3
—
50.9
—
0
10
8
89
0.90
0.00
1.0
1.1
—
—
—
0
0
7
74
0.94
0.00
10.3
11.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
10.7
—
6.8
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
166.8
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.7
—
—
—
0
0
11
110
1.00
0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
0.00
2.3
2.4
66.0
113.1
ug/min
—
6
36
0
9
0.00
0.00
0.0
1.0
—
2.7
—
0
9
0
6
0.00
0.00
0.0
1.5
—
18.2
—
0
6
0
5
0.00
0.00
0.0
2.2
—
3703.4
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.0
1.2
—
—
—
0
0
5
51
0.98
0.00
1.6
2.1
137.6
131.1
g/l
—
5
36
8
86
0.93
0.00
1.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_LEUKAEMIA_NAS – Leukaemia of unspecified cell type

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).