Chromophobe cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

C3_KIDNEY_CHROMOPHOBE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C64
  • Cancer registry: Morphology ICD-O-3 8317
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

162

4. Check minimum number of events

None

162

5. Include endpoints

None

162

6. Filter based on genotype QC (FinnGen only)

162

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12
Name in latin
Carcinoma in situ labii (oris)

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 162 57 105
Unadjusted period prevalence (%) 0.04 0.02 0.05
Median age at first event (years) 67.60 63.46 69.86

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
151
Matched controls
1509
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
+∞
218.2
151
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
190.8
140
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2010.4
158.6
127
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
+∞
43.9
40
*
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
+∞
40.4
37
*
KAD00
NOMESCO Finland
Partial nephrectomy
+∞
34.7
32
*
JN4AD
NOMESCO Finland
Body CT examination
22.6
29.3
43
26
WX408
NOMESCO Finland
General anesthesy, balanced
7.8
28.1
82
199
JN4CD
NOMESCO Finland
Very extensive body CT
71.0
26.0
29
5
B01AB10
ATC
tinzaparin; parenteral
17.2
25.9
42
33
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
40.0
25.9
32
10
WX302
NOMESCO Finland
Thoracal epidural anesthesy
32.0
25.3
33
13
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
17.7
24.5
39
29
KAC10
NOMESCO Finland
Total nephrectomy with capsule
282.7
24.4
24
*
JN4BD
NOMESCO Finland
Extensive body CT
13.4
21.8
39
38
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.5
19.3
50
93
TPH07
NOMESCO Finland
Cathetrisation of artery
7.9
16.9
41
68
KA1AE
NOMESCO Finland
Kidney ultrasound examination
45.6
16.8
20
5
B01AB05
ATC
enoxaparin; parenteral
4.4
16.1
78
292
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
+∞
15.9
15
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
14.8
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
14.5
98
477
U75
ICPC
Malignant neoplasm of kidney
+∞
13.7
13
*
130
Kela drug reimbursment
Malignant tumour
+∞
13.7
13
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
13.7
13
*
WX402
NOMESCO Finland
General anaesthesia
4.8
10.8
38
98
N02AX02
ATC
tramadol; systemic, rectal
3.0
9.6
85
454
WZC30
NOMESCO Finland
Teaching
4.8
9.5
33
83
116
Kela drug reimbursment
Prostate cancer
+∞
9.5
9
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
9.5
9
*
N02BE01
ATC
paracetamol; systemic, rectal
5.8
9.4
142
1103
H02AB02
ATC
dexamethasone; systemic
29.4
8.6
11
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
95.0
8.5
9
*
S18
ICPC
Laceration/cut
2.7
7.8
81
455
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
47.4
7.8
9
*
Z51.5
ICD-10 Finland
Palliative care
10.9
7.7
14
14
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.3
7.6
42
159
L01XE04
ATC
[U] sunitinib; oral
+∞
7.3
7
*
KAC00
NOMESCO Finland
Nephrectomy
+∞
7.3
7
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
7.3
7
*
Y77
ICPC
Malignant neoplasm prostate
+∞
7.3
7
*
KA3LT
NOMESCO Finland
Njurlesion coagulation
+∞
7.3
7
*
197
Kela drug reimbursment
Sunitinib
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
7.3
28
78
SPAT1153
SPAT
Removal of sutures
2.7
7.2
62
309
R4110
NOMESCO Finland
Physiotherapy
2.8
7.1
55
256
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.2
7.1
15
20
XKD00
NOMESCO Finland
Uroflowmetry
3.3
7.0
38
140
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
8.9
7.0
14
17
T81.9
ICD-10 Finland
Unspecified complication of procedure
23.7
6.7
9
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
23.7
6.7
9
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
13.0
6.7
11
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
6.6
48
214
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
6.5
33
117
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
39
32.43
96.61
1.2
1.4
—
—
—
0
0
128
544
7.45
28.84
4.0
3.6
—
—
—
0
0
105
395
5.71
26.60
2.5
1.6
—
—
—
0
0
32
44
8.82
22.94
3.5
2.1
0.2
0.2
g/l
0.11
25
15
123
575
5.73
22.68
9.7
5.4
1.2
1.2
mmol/l
1.07
115
519
113
559
4.38
17.63
7.2
3.7
35.5
35.6
g/l
0.05
106
523
36
75
5.89
17.34
7.4
9.2
—
—
—
0
0
40
98
5.09
16.02
1.4
1.1
—
—
—
0
0
87
379
3.80
15.90
2.4
2.2
—
—
—
0
0
83
352
3.78
15.76
4.3
2.6
—
—
—
0
0
117
630
4.09
15.31
10.3
5.8
1.2
1.2
mmol/l
0.83
96
550
51
159
4.22
15.00
6.6
6.9
97.3
94.7
%
3.43
51
154
105
538
3.70
14.56
8.0
9.9
1.1
1.4
inr
2.14
31
130
82
366
3.51
14.02
4.3
2.7
0.1
0.5
e6/l
4.55
67
269
68
270
3.62
13.97
3.3
2.1
2.3
4.3
e6/l
2.12
60
235
86
398
3.47
13.83
4.5
2.9
358.6
223.2
e6/l
0.14
70
302
52
175
3.90
13.62
6.5
6.7
-0.7
1.4
mmol/l
3.61
43
138
82
376
3.39
13.25
7.9
3.5
7.4
7.4
ph
0.91
17
53
150
1020
7.35
13.15
12.0
5.6
81.9
74.9
u/l
1.03
144
941
52
180
3.78
13.02
6.8
6.2
106.0
104.0
mmol/l
2.86
52
174
48
160
3.84
12.66
8.9
5.9
1.0
1.0
mmol/l
0.08
43
148
41
127
3.98
11.95
8.9
7.9
—
—
—
0
0
90
463
3.12
11.55
5.1
3.4
44.8
91.4
e6/l
0.79
75
332
134
881
4.01
11.17
4.9
4.0
—
—
—
0
0
26
66
4.50
9.76
3.2
1.4
5.0
2.5
ug/l
0.56
18
54
76
384
2.84
9.65
5.5
2.1
2.4
2.3
mmol/l
1.22
66
327
55
237
3.00
9.31
3.2
2.6
586.0
569.8
mosm/kgh2o
0.24
47
197
70
356
2.70
8.56
2.7
2.9
—
—
—
0
0
111
711
2.78
8.47
11.0
6.5
4.1
4.4
e9/l
0.67
96
629
65
352
2.41
6.64
3.8
4.2
—
—
—
0
0
155
1327
4.89
6.11
20.8
13.2
34.9
23.3
mg/l
3.19
145
1015
38
169
2.63
5.81
4.4
2.8
25.9
23.3
%
0.58
31
149
48
241
2.41
5.68
5.1
2.1
2.5
2.4
mmol/l
2.17
43
208
45
222
2.42
5.52
1.7
2.0
30.1
29.6
s
0.29
45
215
51
283
2.17
4.67
1.3
1.3
—
—
—
0
0
16
52
3.30
4.21
2.9
1.8
—
—
—
0
0
24
106
2.48
3.67
4.9
4.6
—
—
—
0
0
123
987
2.02
3.62
4.6
4.3
15.3
11.9
mm/h
1.51
114
901
50
300
1.96
3.61
9.1
4.5
—
—
—
0
0
12
36
3.52
3.55
2.9
3.4
—
—
—
0
0
155
1400
3.48
3.54
22.2
12.4
—
—
—
0
0
21
90
2.53
3.41
4.4
2.9
—
—
—
0
0
7
10
7.26
3.40
1.0
1.1
—
—
—
0
0
122
990
1.94
3.29
5.0
4.1
—
—
—
0
0
85
645
1.67
2.62
4.4
3.5
0.0
0.0
estimate
0.00
25
88
69
496
1.68
2.62
4.3
3.2
1677.3
198.4
mg/l
0.71
45
316
68
487
1.68
2.62
4.1
3.3
—
—
—
0
0
51
339
1.74
2.57
5.2
3.7
0.0
0.0
estimate
0.49
23
89
6
11
5.62
2.56
1.8
1.1
—
—
—
0
0
83
633
1.64
2.46
5.5
4.8
0.0
0.0
estimate
0.00
24
95
61
430
1.67
2.46
6.3
5.9
—
—
—
0
0
77
581
1.62
2.36
11.6
7.7
0.0
0.0
e9/l
0.00
66
471
71
527
1.62
2.31
3.6
2.8
274.9
132.4
ug/l
1.10
62
494
70
521
1.60
2.24
4.9
4.0
18.4
9.4
mg/mmol
0.88
42
330
69
512
1.61
2.23
4.0
3.1
7.1
7.9
mmol/l
0.54
54
432
155
1442
2.73
2.19
14.6
9.4
26.1
26.3
u/l
0.04
150
1378
81
627
1.58
2.18
4.5
3.5
0.0
0.0
estimate
0.00
25
97
6
14
4.41
2.17
2.8
1.4
—
—
—
0
0
84
657
1.58
2.16
6.0
5.5
1.7
1.8
e9/l
0.43
70
583
84
657
1.58
2.16
6.0
5.9
0.2
0.2
e9/l
0.00
70
583
82
641
1.57
2.09
6.0
5.4
0.6
0.6
e9/l
0.30
69
555
82
642
1.56
2.07
6.0
5.4
0.0
0.0
e9/l
0.28
70
562
53
378
1.60
1.98
4.3
2.6
396.8
10538.1
umol/l
2.26
45
331
7
22
3.28
1.90
1.6
1.2
—
—
—
0
0
21
116
1.93
1.89
1.8
1.5
—
—
—
0
0
14
66
2.23
1.88
1.5
1.5
—
—
—
0
0
17
88
2.04
1.83
2.1
1.2
—
—
—
0
0
20
111
1.91
1.78
4.8
3.1
—
—
—
0
0
6
18
3.42
1.76
2.8
1.1
—
—
—
0
0
6
19
3.24
1.67
1.2
1.2
—
—
—
0
0
52
383
1.53
1.66
3.1
2.7
0.7
0.8
ug/l
0.42
39
257
20
114
1.86
1.65
2.0
1.6
—
—
—
0
0
26
161
1.73
1.65
6.5
3.7
—
—
—
0
0
8
32
2.58
1.62
3.6
1.2
78.6
53.6
mg/l
—
8
25
8
32
2.58
1.62
3.6
1.2
23.4
35.2
mg/l
—
8
26
6
20
3.07
1.59
4.5
3.3
—
—
—
0
0
6
20
3.07
1.59
2.3
2.8
3.6
5.1
e9/l
—
6
20
6
20
3.07
1.59
2.3
3.7
56.2
60.3
%
—
6
20
25
158
1.69
1.48
6.7
3.7
6.0
5.8
kpa
0.74
25
151
6
22
2.79
1.45
1.7
2.5
—
—
—
0
0
41
295
1.52
1.44
4.6
3.5
—
—
—
0
0
147
1367
1.81
1.39
5.2
5.0
4.4
4.5
mmol/l
0.40
135
1257
11
54
2.11
1.36
4.5
4.2
4.0
4.0
mmol/l
0.13
11
49
0
38
0.00
1.36
0.0
4.5
—
—
—
0
0
44
330
1.46
1.26
2.8
2.1
3.1
3.0
mg/l
0.03
35
283
5
19
2.68
1.22
1.0
1.3
—
—
—
0
0
145
1357
1.65
1.14
5.1
5.0
1.4
1.4
mmol/l
1.16
132
1236
144
1346
1.63
1.14
5.6
4.9
6.2
6.1
mmol/l
0.22
134
1217
25
171
1.55
1.11
1.3
1.2
—
—
—
0
0
5
21
2.42
1.10
3.8
2.5
—
—
—
0
0
38
286
1.43
1.07
1.7
1.7
1297.0
1216.7
nmol/l
0.18
24
226
44
342
1.39
1.03
1.7
1.6
15.3
20.7
nmol/l
2.32
37
298
141
1318
1.54
1.03
4.5
4.5
1.4
1.3
mmol/l
0.69
128
1191
81
694
1.33
1.02
5.5
4.0
4.6
2.1
ug/l
0.49
74
621
148
1400
1.66
1.01
5.7
5.6
2.6
2.6
mmol/l
0.15
133
1285
134
1242
1.46
1.01
5.6
4.4
1.9
2.0
mu/l
0.09
121
1113
112
1009
1.36
0.99
4.7
3.6
15.1
14.8
pmol/l
0.62
103
900
37
281
1.41
0.99
1.5
1.7
1.4
1.1
mg/l
0.39
27
224
17
110
1.61
0.95
2.6
1.2
67.9
66.5
g/l
0.31
17
99
18
119
1.58
0.93
4.1
3.4
—
—
—
0
0
24
172
1.46
0.87
1.3
1.3
760.0
489.3
titre
—
8
43
127
1178
1.36
0.84
27.9
14.6
38.6
39.8
%
0.77
87
800
47
382
1.32
0.83
2.1
1.7
1.5
1.3
mmol/l
0.33
38
323
7
121
0.56
0.82
1.1
1.4
—
—
—
0
0
140
1322
1.43
0.80
6.8
6.6
39.8
40.9
mmol/mol
0.77
131
1231
0
25
0.00
0.79
0.0
2.4
—
—
—
0
0
0
26
0.00
0.79
0.0
2.4
—
105.8
—
0
26
0
26
0.00
0.79
0.0
1.6
—
—
—
0
0
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
0
26
0.00
0.79
0.0
2.4
—
4.2
—
0
26
0
27
0.00
0.78
0.0
1.6
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.6
—
—
—
0
0
42
340
1.32
0.76
3.9
3.2
—
—
—
0
0
20
145
1.43
0.70
1.8
1.8
—
—
—
0
0
10
154
0.63
0.68
1.3
1.5
—
—
—
0
0
19
139
1.42
0.64
3.2
3.6
323.4
224.0
ng/l
0.32
19
127
5
30
1.69
0.62
1.2
1.0
—
—
—
0
0
0
20
0.00
0.61
0.0
1.8
—
—
—
0
0
6
96
0.61
0.54
1.2
1.6
—
—
—
0
0
6
99
0.59
0.54
2.5
3.0
—
—
—
0
0
25
198
1.31
0.53
1.0
1.3
4.7
14.7
u/ml
—
10
69
7
47
1.51
0.48
1.1
1.3
—
—
—
0
0
10
68
1.50
0.48
6.0
4.2
—
—
—
0
0
7
48
1.48
0.47
1.0
1.9
—
—
—
0
0
5
31
1.63
0.43
2.4
3.2
7.4
7.4
ph
—
5
23
5
32
1.58
0.42
6.2
2.5
23.4
25.3
mmol/l
—
5
27
63
569
1.18
0.41
3.8
3.7
127.9
47.6
ng/l
0.56
50
407
0
15
0.00
0.41
0.0
7.4
—
12.0
—
0
15
0
19
0.00
0.39
0.0
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
2.6
—
628.6
—
0
10
5
36
1.40
0.38
1.2
1.7
—
—
—
0
0
9
71
1.28
0.37
4.4
3.2
1.3
0.2
e6/l
—
9
71
6
86
0.69
0.34
3.3
2.4
—
—
—
0
0
25
212
1.21
0.32
1.1
1.3
25.4
42.4
iu/ml
—
10
68
31
269
1.19
0.32
3.5
4.4
—
—
—
0
0
16
130
1.26
0.30
4.1
2.7
3.9
4.5
kpa
0.86
16
122
63
583
1.13
0.29
2.1
2.0
97.1
92.1
pmol/l
0.29
26
312
15
124
1.23
0.25
1.4
2.1
73.3
67.1
e9/l
—
9
98
5
37
1.36
0.24
1.6
1.1
—
—
—
0
0
5
37
1.36
0.24
1.6
1.1
—
—
—
0
0
5
37
1.36
0.24
1.6
1.1
—
—
—
0
0
46
423
1.12
0.23
3.6
4.0
—
—
—
0
0
5
40
1.26
0.22
2.6
2.8
—
—
—
0
0
15
126
1.21
0.22
1.1
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
482.7
—
0
7
0
13
0.00
0.21
0.0
1.1
—
3869.1
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
4803.3
—
0
9
6
49
1.23
0.20
1.0
1.5
—
—
—
0
0
17
147
1.17
0.19
1.3
1.7
—
—
—
0
0
8
69
1.17
0.17
5.0
4.7
—
—
—
0
0
8
70
1.15
0.16
1.4
1.3
—
—
—
0
0
7
89
0.78
0.15
2.7
2.3
1.0
1.3
%
—
7
89
22
200
1.12
0.13
1.8
1.8
—
—
—
0
0
11
96
1.16
0.10
1.0
1.3
—
—
—
0
0
5
43
1.17
0.10
1.2
1.2
—
—
—
0
0
5
60
0.83
0.08
3.6
11.5
—
—
—
0
0
45
468
0.95
0.08
3.2
3.3
—
—
—
0
0
8
75
1.07
0.07
1.3
1.2
—
—
—
0
0
23
243
0.94
0.06
1.3
1.3
1.9
2.8
g/l
2.13
11
137
10
110
0.90
0.05
1.1
1.7
—
—
—
0
0
20
210
0.95
0.04
23.2
24.9
—
1.3
—
0
31
15
156
0.96
0.00
1.1
1.5
—
—
—
0
0
45
454
0.99
0.00
2.1
2.1
174.1
184.6
u/l
0.12
40
417
112
1124
0.99
0.00
33.9
17.9
331.1
332.7
g/l
1.17
112
1117
10
97
1.03
0.00
1.3
1.2
—
17.4
—
0
7
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
8.1
—
735.3
—
0
9
0
5
0.00
0.00
0.0
1.0
—
3.3
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
11.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
52.0
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_KIDNEY_CHROMOPHOBE_EXALLC – Chromophobe cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).