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Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

C3_RENAL_CELL_CARCINOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C64
  • Cancer registry: Morphology ICD-O-3 8312|831[6-9]
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

1265

4. Check minimum number of events

None

1265

5. Include endpoints

None

1265

6. Filter based on genotype QC (FinnGen only)

1265

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1265 474 791
Unadjusted period prevalence (%) 0.28 0.16 0.35
Median age at first event (years) 63.23 60.73 64.72

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1176
Matched controls
11771
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
323.0
1012
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
227.2
323.0
574
49
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
323.0
1021
*
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
+∞
323.0
334
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
+∞
323.0
413
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
310
*
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
+∞
161.2
151
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
339.8
149.3
148
5
7125
FHL
Nephrectomy (extrrafascial)
+∞
147.0
138
*
197
Kela drug reimbursment
Sunitinib
+∞
122.0
115
*
JN4AD
NOMESCO Finland
Body CT examination
13.4
115.9
212
190
KAC00
NOMESCO Finland
Nephrectomy
603.1
112.9
110
*
JN4BD
NOMESCO Finland
Extensive body CT
10.1
111.3
237
287
L01XE04
ATC
[U] sunitinib; oral
+∞
111.2
105
*
C64.80
ICD-10 Finland
Wilms tumour
+∞
110.1
104
*
KAD00
NOMESCO Finland
Partial nephrectomy
578.8
108.6
106
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
154.4
107.1
112
8
1890B
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,ADENOCARCINOMA]
+∞
106.9
101
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
104.8
99
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
104.8
99
*
180
Kela drug reimbursment
Interferon alfa
+∞
100.5
95
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.5
86.1
288
653
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
437.0
83.0
82
*
H02AB02
ATC
dexamethasone; systemic
25.9
81.6
115
49
JN4CD
NOMESCO Finland
Very extensive body CT
19.2
76.0
118
68
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
75.8
72
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
73.7
70
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
69.4
66
*
U75
ICPC
Malignant neoplasm of kidney
673.8
65.5
64
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
63.1
60
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
61.9
256
703
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
88.7
60.6
67
8
WX302
NOMESCO Finland
Thoracal epidural anesthesy
12.4
59.4
110
97
B01AB10
ATC
tinzaparin; parenteral
7.4
57.2
144
218
116
Kela drug reimbursment
Prostate cancer
+∞
56.7
54
*
1502
Kela drug reimbursment
Cabozantinib
+∞
56.7
54
*
3012
Kela drug reimbursment
Cabozantinib
+∞
55.6
53
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
22.8
54.3
79
37
1890X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,EI HIST VAHV]
+∞
53.5
51
*
C648
ICD-10 Finland
NA
+∞
52.5
50
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
141.3
51.2
54
*
N02AX02
ATC
tramadol; systemic, rectal
2.6
50.0
585
3279
322
Kela drug reimbursment
Sunitinib
+∞
49.3
47
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
49.3
47
*
159
Kela drug reimbursment
Pazopanib
+∞
48.2
46
*
N02AA05
ATC
oxycodone; systemic
3.5
43.7
235
787
115
Kela drug reimbursment
Breast cancer
+∞
43.0
41
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
41.6
330
1443
158
Kela drug reimbursment
Everolimus
+∞
40.9
39
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
46.3
40.3
49
11
A04AA02
ATC
granisetron; systemic, transdermal
144.9
40.0
42
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
39.8
38
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
38.4
324
1458
L01XE11
ATC
[U] pazopanib; oral
+∞
37.7
36
*
L01XE26
ATC
[U] cabozantinib; oral
+∞
37.7
36
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
37.7
36
*
B01AB05
ATC
enoxaparin; parenteral
2.5
37.5
392
1984
Z51.5
ICD-10 Finland
Palliative care
7.4
37.2
91
131
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
367.9
36.2
36
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.2
35.8
100
173
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
27.7
35.2
48
18
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
34.5
165
499
L03AA04
ATC
NA
346.6
34.1
34
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
76.4
33.0
37
5
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
174.8
32.9
34
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.2
32.0
104
216
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.5
31.9
71
88
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
31.4
30
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
31.4
30
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
31.4
30
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.7
31.3
82
130
XX3DW
NOMESCO Finland
Time consuming IT work
4.8
30.7
108
244
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.8
29.2
85
155
R31
ICD-10 Finland
Unspecified haematuria
3.0
28.9
188
707
L03AB05
ATC
interferon alfa-2b; parenteral
106.0
28.8
31
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
28.2
27
*
L01EX07
ATC
cabozantinib; oral
+∞
28.2
27
*
WZC30
NOMESCO Finland
Teaching
3.3
28.0
154
514
L02AE02
ATC
leuprorelin; implant, parenteral
54.7
27.3
32
6
L01BC06
ATC
capecitabine; oral
+∞
27.2
26
*
UKC02
NOMESCO Finland
Cystoscopy
2.5
27.0
252
1172
A04AA01
ATC
ondansetron; systemic, rectal
9.1
26.4
56
64
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
26.1
25
*
18900
ICD-8 Finland
Malignant neoplasm of other and unspecified urinary organs, Kidney, except pelvis
+∞
26.1
25
*
KA3LT
NOMESCO Finland
Njurlesion coagulation
266.0
25.8
26
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
266.0
25.8
26
*
L03AB04
ATC
interferon alfa-2a; parenteral
266.0
25.8
26
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
25.1
535
3542
WF002
NOMESCO Finland
Radical radiotherapy
59.3
25.1
29
5
198
Kela drug reimbursment
Sorafenib
+∞
25.1
24
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
25.1
24
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
24.7
155
567
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
11.1
24.7
47
44
L02BG04
ATC
letrozole; oral
49.4
24.4
29
6
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
24.0
23
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.7
23.9
70
129
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
88.6
23.7
26
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
244.6
23.7
24
*
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
42.3
23.7
29
7
168
Kela drug reimbursment
Axitinib
+∞
23.0
22
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
23.0
22
*
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
+∞
23.0
22
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
22.8
192
836
A11CC03
ATC
alfacalcidol; systemic
5.7
22.0
64
117
L01XE10
ATC
[U] everolimus; oral
+∞
21.9
21
*
L02BB03
ATC
bicalutamide; oral
223.8
21.7
22
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
21.2
140
528
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
20.9
20
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
213.5
20.6
21
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
19.9
420
2706
SPAT1153
SPAT
Removal of sutures
1.9
19.1
362
2238
M04AA01
ATC
allopurinol; systemic
2.1
18.3
225
1172
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
7.5
18.3
43
59
XKD00
NOMESCO Finland
Uroflowmetry
2.1
18.1
230
1213
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
18.0
109
389
Y77
ICPC
Malignant neoplasm prostate
+∞
17.7
17
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
17.7
17
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
17.7
17
*
M05BA02
ATC
clodronic acid; systemic
+∞
17.7
17
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
17.7
17
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
17.7
17
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
17.7
17
*
L01XE05
ATC
[U] sorafenib; oral
+∞
17.7
17
*
L02BA01
ATC
tamoxifen; oral
+∞
17.7
17
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
17.7
17
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
182.5
17.6
18
*
L03AA13
ATC
pegfilgrastim; parenteral
182.5
17.6
18
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.2
17.5
94
309
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.3
17.2
41
58
HAB40
NOMESCO Finland
Wedge excision of mammary gland
22.2
16.9
24
11
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.0
16.7
68
178
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.8
16.7
42
64
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
16.7
16
*
1890A
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,NEPHROBLASTOMA]
+∞
16.7
16
*
L01XE17
ATC
[U] axitinib; oral
+∞
16.7
16
*
340
Kela drug reimbursment
Everolimus
+∞
16.7
16
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
91.3
16.6
18
*
N18.8
ICD-10 Finland
Other chronic renal failure
3.9
16.5
68
180
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
172.2
16.5
17
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
16.5
363
2338
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
16.3
128
534
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
30.5
16.1
21
7
TK800
NOMESCO Finland
Hemodialysis
5.2
15.9
49
97
Z49.0
ICD-10 Finland
Preparatory care for dialysis
9.4
15.7
32
35
WW500
NOMESCO Finland
Blood transfusion
4.9
15.7
51
107
A12AA04
ATC
calcium carbonate; oral
5.8
15.7
44
78
343
Kela drug reimbursment
Pazopanib
+∞
15.7
15
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
15.7
15
*
A79
ICPC
Malignancy NOS
+∞
15.7
15
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
15.7
15
*
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
22.4
15.6
22
10
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
162.0
15.5
16
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.1
15.5
32
36
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.7
15.5
53
118
R50.9
ICD-10 Finland
Fever, unspecified
2.2
15.2
164
803
HA1AA
NOMESCO Finland
X-ray mammography
5.2
15.1
47
94
N02AA01
ATC
morphine; systemic, rectal
8.2
15.1
33
41
M05BX04
ATC
denosumab; parenteral
3.6
14.8
67
193
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
14.6
14
*
L03AA02
ATC
filgrastim; parenteral
81.1
14.6
16
*
U14
ICPC
Kidney symptom/complaint
6.5
14.5
37
58
JN6AD
NOMESCO Finland
CT of torso and neck
36.5
14.5
18
5
ZXC96
NOMESCO Finland
Robot assisted procedure
15.6
14.4
23
15
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
14.4
169
856
J01MA02
ATC
ciprofloxacin; systemic
1.7
14.4
457
3254
C08CA01
ATC
amlodipine; oral
1.6
13.9
475
3439
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.4
13.8
32
44
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
14.9
13.6
22
15
205
Kela drug reimbursment
Chronic hypertension
1.6
13.6
441
3147
361
Kela drug reimbursment
Axitinib
+∞
13.6
13
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
13.6
13
*
KAC20
NOMESCO Finland
Nephroureterectomy
+∞
13.6
13
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
13.6
13
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
13.6
13
*
B02AA02
ATC
tranexamic acid; systemic
2.3
13.5
129
594
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
141.5
13.5
14
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.6
13.4
34
53
Z31.5
ICD-10 Finland
Genetic counselling
5.8
13.4
37
65
GD1AD
NOMESCO Finland
Thorax CT examination
3.6
13.3
59
168
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.2
13.3
50
123
N18.0
ICD-10 Finland
End-stage renal disease
6.2
12.9
34
56
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
12.5
12
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
12.5
12
*
PHE70
NOMESCO Finland
Thrombectomy of inferior vena cava
+∞
12.5
12
*
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
12.5
12
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
12.5
12
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
12.5
12
*
L01EX01
ATC
sunitinib; oral
+∞
12.5
12
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
12.5
12
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
12.5
12
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
12.5
141
701
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
131.3
12.5
13
*
137
Kela drug reimbursment
Uraemia requiring dialysis
9.8
12.3
24
25
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.2
12.0
23
23
V03AE01
ATC
polystyrene sulfonate; oral
5.3
11.7
35
68
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
11.7
400
2864
UJF32
NOMESCO Finland
Coloscopy
1.7
11.6
273
1768
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
11.5
11
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
+∞
11.5
11
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
11.5
11
*
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
+∞
11.5
11
*
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
+∞
11.5
11
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
11.5
11
*
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
+∞
11.5
11
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
121.1
11.4
12
*
7124
FHL
Nephrectomy (simple
121.1
11.4
12
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.9
11.3
20
17
S18
ICPC
Laceration/cut
1.6
11.3
417
3042
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.1
11.3
43
108
B03XA02
ATC
darbepoetin alfa; parenteral
5.0
11.2
35
72
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
11.1
70
257
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
6.2
11.1
29
48
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
11.0
89
375
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
7.5
11.0
25
34
J01MA12
ATC
levofloxacin; systemic
1.8
10.9
209
1264
ZX120
NOMESCO Finland
Intravenous
2.4
10.9
95
419
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
43.7
10.9
13
*
C03CA01
ATC
furosemide; systemic
1.5
10.8
458
3441
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.7
912
8027
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
60.5
10.6
12
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
60.5
10.6
12
*
RD211
NOMESCO Finland
NA
3.3
10.6
53
167
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
110.9
10.4
11
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
10.4
10
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
10.4
10
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
10.4
10
*
NA049
NOMESCO Finland
Radiotherapy of methastasis in spine
+∞
10.4
10
*
C79.7
ICD-10 Finland
Secondary malignant neoplasm of adrenal gland
+∞
10.4
10
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
10.4
10
*
Z85.5
ICD-10 Finland
Personal history of malignant neoplasm of urinary tract
+∞
10.4
10
*
AA049
NOMESCO Finland
Radiotherapy of metasthasis in the brain
+∞
10.4
10
*
V03AE02
ATC
sevelamer; oral
16.2
10.4
16
10
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.0
10.1
27
46
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
10.0
63
232
Z90.5
ICD-10 Finland
Acquired absence of kidney
55.4
9.7
11
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.9
9.6
23
34
B05DA
ATC
Isotonic solutions
10.1
9.5
18
18
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
15.2
9.5
15
10
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.5
334
2382
TKE00
NOMESCO Finland
Needle biopsy of prostate
3.1
9.5
50
165
JLC10
NOMESCO Finland
Distal pancreatectomy
100.8
9.4
10
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
9.4
9
*
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
+∞
9.4
9
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
9.4
9
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
9.4
9
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
9.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
9.4
9
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.4
9
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
9.4
9
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
9.4
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.2
9.4
48
155
JAH00
NOMESCO Finland
Laparotomy
3.8
9.4
38
102
C02AC05
ATC
moxonidine; oral
2.5
9.4
71
293
ZXA05
NOMESCO Finland
Left side
1.6
9.3
298
2078
ZXA00
NOMESCO Finland
Right side
1.6
9.2
310
2188
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
18.7
8.9
13
7
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
8.9
85
394
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.9
220
1431
A02BC02
ATC
pantoprazole; systemic
1.4
8.8
655
5458
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.1
8.8
33
83
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
50.3
8.7
10
*
127
Kela drug reimbursment
Transplant complication
7.7
8.7
19
25
A06AD11
ATC
lactulose; oral
1.7
8.6
204
1310
JMA10
NOMESCO Finland
Transabdominal total splenectomy
27.7
8.5
11
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
27.7
8.5
11
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
8.5
73
321
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
90.6
8.4
9
*
B03XA01
ATC
erythropoietin; parenteral
6.8
8.4
20
30
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
8.3
8
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
8.3
8
*
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
+∞
8.3
8
*
C68.9
ICD-10 Finland
Malignant neoplasm: Urinary organ, unspecified
+∞
8.3
8
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
8.3
8
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
8.3
8
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
8.3
8
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
8.3
8
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
8.3
8
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
8.3
8
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
8.3
8
*
M907, C6488
ICD-10 Finland
NA
+∞
8.3
8
*
E83.50
ICD-10 Finland
Hypercalcemia
5.9
8.3
22
38
Z49.2
ICD-10 Finland
Other dialysis
9.5
8.3
16
17
WX402
NOMESCO Finland
General anaesthesia
1.9
8.1
117
643
TK820
NOMESCO Finland
Peritoneal dialysis
17.3
8.1
12
7
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
9.0
8.0
16
18
Z94.0
ICD-10 Finland
Kidney transplant status
9.0
8.0
16
18
JFB46
NOMESCO Finland
Resection of sigmoid colon
5.9
8.0
21
36
R33
ICD-10 Finland
Retention of urine
1.9
8.0
114
624
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.6
7.9
26
58
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
7.8
55
219
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.9
7.8
30
78
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
7.8
31
83
GDC00
NOMESCO Finland
Lobectomy of lung
45.2
7.7
9
*
J01EA01
ATC
trimethoprim; systemic
1.5
7.7
255
1782
1530
FHL
Urethrocystoscopy
3.3
7.6
36
111
BCA30
NOMESCO Finland
Unilateral adrenalectomy
18.5
7.6
11
6
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
7.6
48
177
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
25.2
7.6
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
7.5
296
2155
Z3231
NOMESCO Finland
Registered nurse
1.5
7.4
267
1902
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
80.5
7.4
8
*
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
80.5
7.4
8
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
80.5
7.4
8
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
80.5
7.4
8
*
ZX112
NOMESCO Finland
Subcutaneous
6.5
7.4
18
28
XJH00
NOMESCO Finland
Transanal ultrasonography
2.1
7.4
81
400
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
7.4
163
1027
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
10.9
7.3
13
12
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
7.3
7
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
7.3
7
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
7.3
7
*
L02BG03
ATC
anastrozole; oral
+∞
7.3
7
*
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
+∞
7.3
7
*
Z80.8
ICD-10 Finland
Family history of malignant neoplasm of other organs or systems
+∞
7.3
7
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
7.3
7
*
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
7.3
7
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
7.3
7
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
7.3
7
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
7.3
7
*
B05DB
ATC
Hypertonic solutions
9.4
7.3
14
15
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.9
7.3
28
73
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.8
7.2
28
74
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
6.6
7.1
17
26
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
4.1
7.1
26
65
A06AH03
ATC
naloxegol; oral
8.8
7.1
14
16
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
10.1
7.0
13
13
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
7.0
97
525
G04CA02
ATC
tamsulosin; oral
1.5
7.0
325
2441
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
6.8
60
269
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
40.3
6.8
8
*
N07BC02
ATC
methadone; systemic
40.3
6.8
8
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
6.8
47
185
7321
FHL
TU biopsy, coagulation or laser
16.8
6.7
10
6
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
5.2
6.6
19
37
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
10.1
6.5
12
12
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
5.7
6.5
17
30
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.4
695
6032
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
70.2
6.4
7
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
70.2
6.4
7
*
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
14.4
6.4
10
7
306
Kela drug reimbursment
Erythropoietin and darbepoetin
14.4
6.4
10
7
KWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in urological surgery
14.4
6.4
10
7
C08CA13
ATC
lercanidipine; oral
1.6
6.4
161
1050
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
6.3
106
614
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
5.2
6.3
18
35
L02AE03
ATC
goserelin; implant
18.1
6.3
9
5
U79
ICPC
Neoplasm urinary tract unspecified
+∞
6.3
6
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
6.3
6
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
6.3
6
*
8318/3-C64.9
ICD-O-3
Renal cell carcinoma, sarcomatoid of kidney, NOS
+∞
6.3
6
*
8316/3-C64.9
ICD-O-3
Cyst-associated renal cell carcinoma of kidney, NOS
+∞
6.3
6
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
6.3
6
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
6.3
6
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
6.3
6
*
KA3CT
NOMESCO Finland
Biopsy of kidney under CT guidance
+∞
6.3
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.3
6
*
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
+∞
6.3
6
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
+∞
6.3
6
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
6.3
6
*
8140/3-C18.2
ICD-O-3
Adenocarcinoma, NOS, of ascending colon
+∞
6.3
6
*
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
6.3
6
*
L02BG06
ATC
exemestane; oral
+∞
6.3
6
*
PJD44
NOMESCO Finland
Excision of iliac lymph nodes
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
1891X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Renal pelvis[NEOPLASMA MALIGNUM PELVIS RENIS,EI HIST VAHV]
+∞
6.3
6
*
L01EX03
ATC
pazopanib; oral
+∞
6.3
6
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
6.3
6
*
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
+∞
6.3
6
*
A04AD12
ATC
aprepitant; systemic
+∞
6.3
6
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
6.3
6
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
6.3
6
*
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
6.3
6
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
+∞
6.3
6
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.8
6.2
19
40
GDA20
NOMESCO Finland
Excision of lesion of lung
26.8
6.2
8
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
6.2
41
159
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
3.7
6.2
25
69
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
6.2
47
195
S15
ICPC
Foreign body in skin
2.2
6.2
59
277
JFB30
NOMESCO Finland
Right hemicolectomy
5.8
6.1
16
28
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
12.6
6.1
10
8
196
Kela drug reimbursment
Paricalcitol and cinacalcet
12.6
6.1
10
8
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
12.6
6.1
10
8
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
12.6
6.1
10
8
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.6
6.1
12
14
321
Kela drug reimbursment
Paricalcitol and cinacalcet
8.6
6.1
12
14
SPAT1109
SPAT
Analgesia with portable analgesic pump
8.6
6.1
12
14
L04AA06
ATC
mycophenolic acid; systemic
4.9
6.1
18
37

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_RENAL_CELL_CARCINOMA_EXALLC – Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).