Tracheo-bronchomalasia

TRACHEOBRONCHOMAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J39.8
  • Cause of death: ICD-10 J39.8

2 out of 7 registries used, show all original rules.

172

4. Check minimum number of events

None

172

5. Include endpoints

None

172

6. Filter based on genotype QC (FinnGen only)

172

Control definitions (FinnGen only)

Control exclude
ASTHMA_COMORB

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J39
Name in latin
Alii morbi tractus respiratorii superioris specificati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 959 617 340
Only index persons 905 596 309
Unadjusted period prevalence (%)
Whole population 0.01 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 49.42 48.58 51.04
Only index persons 49.18 48.54 50.40

-FinnGen-

Key figures

All Female Male
Number of individuals 172 122 50
Unadjusted period prevalence (%) 0.04 0.04 0.02
Median age at first event (years) 52.74 51.04 56.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
157
Matched controls
1569
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J39.8
ICD-10 Finland
Other specified diseases of upper respiratory tract
+∞
224.8
157
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
127.9
90.4
92
17
XG474
NOMESCO Finland
Exhalation nntrogen oxide
83.6
50.6
55
10
J45.9
ICD-10 Finland
Asthma, unspecified
13.7
37.1
71
89
R03AC02
ATC
salbutamol; inhalant
9.2
31.9
130
538
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
46.1
29.9
36
10
R03AK08
ATC
formoterol and beclometasone; inhalant
51.6
28.1
33
8
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.3
23.8
81
227
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
22.8
20.9
30
16
J39.9
ICD-10 Finland
Disease of upper respiratory tract, unspecified
56.2
20.8
24
5
R03BA08
ATC
ciclesonide; inhalant
10.7
20.4
41
50
A02BC02
ATC
pantoprazole; systemic
5.4
20.2
120
592
XQ800
NOMESCO Finland
Prick test
10.3
19.9
41
52
H02AB06
ATC
prednisolone; systemic
4.6
18.0
89
347
J45.1
ICD-10 Finland
Nonallergic asthma
13.0
16.9
30
28
R06.0
ICD-10 Finland
Dyspnoea
5.9
16.7
52
121
R05
ICD-10 Finland
Cough
5.6
16.6
55
138
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
7.9
15.9
38
61
A02BC05
ATC
esomeprazole; systemic
4.2
15.8
83
329
G47.3
ICD-10 Finland
Sleep apnoea
6.5
15.4
43
86
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
5.6
15.4
50
121
R01AD12
ATC
fluticasone furoate; nasal
4.0
14.9
82
334
103
Kela drug reimbursment
Diabetes, insulin-treated
+∞
14.8
14
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
14.8
14
*
R49.01
ICD-10 Finland
Functional dysphonia
15.5
14.8
24
18
I25.1
ICD-10 Finland
Atherosclerotic heart disease
58.9
14.1
16
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
16.8
14.1
22
15
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
28.8
13.7
18
7
C07AB07
ATC
bisoprolol; oral
4.3
13.5
60
199
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.0
13.3
47
123
R03DC03
ATC
montelukast; oral
4.9
13.1
47
125
I48
ICD-10 Finland
Atrial fibrillation and flutter
76.2
12.8
14
*
R03BA05
ATC
fluticasone; inhalant
4.6
12.1
46
129
SPAT1249
SPAT
Treatment-related counselling outside office
3.5
12.1
78
345
R5140
NOMESCO Finland
Monitoring the use of the aid
10.9
11.7
22
23
J38.3
ICD-10 Finland
Other diseases of vocal cords
+∞
11.6
11
*
R03BB04
ATC
tiotropium bromide; inhalant
9.4
11.3
23
28
SPAT1262
SPAT
Handing over of treatment supplies
8.1
11.1
25
36
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
30.5
10.9
14
5
WX780
NOMESCO Finland
Remote monitoring CPAP
23.5
10.9
15
7
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
23.5
10.9
15
7
N03AX12
ATC
gabapentin; oral
5.7
10.9
32
67
Z01.8
ICD-10 Finland
Other specified special examinations
4.2
10.9
45
136
T90
ICPC
Diabetes non-insulin dependent
15.7
10.8
17
12
207
Kela drug reimbursment
Chronic arrhythmias
+∞
10.5
10
*
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
43.1
10.1
12
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.3
10.0
24
38
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
28.1
10.0
13
5
N03AX16
ATC
pregabalin; oral
4.1
9.9
42
129
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
9.9
30
65
A02BC03
ATC
lansoprazole; oral
3.7
9.8
49
173
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
8.2
9.6
21
29
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
106.2
9.5
10
*
R03BA01
ATC
beclometasone; inhalant
4.4
9.5
36
99
J45
ICD-10 Finland
Asthma
5.5
9.5
28
59
A10BA02
ATC
metformin; oral
14.9
9.4
15
11
E66.01
ICD-10 Finland
Obesity due to excess calories
14.9
9.4
15
11
R01AD08
ATC
fluticasone; nasal
3.1
9.4
66
297
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
13.7
9.1
15
12
A02BC01
ATC
omeprazole; systemic
3.5
9.0
47
169
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
3.3
9.0
54
217
WX723
NOMESCO Finland
CPAP therapy
15.2
8.9
14
10
UJF32
NOMESCO Finland
Coloscopy
3.8
8.9
41
135
R06AE07
ATC
cetirizine; oral
2.8
8.8
82
440
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.3
8.8
50
193
N02AJ06
ATC
codeine and paracetamol; systemic
2.9
8.7
68
326
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.9
8.7
71
350
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
94.9
8.5
9
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
94.9
8.5
9
*
SPAT1301
SPAT
No procedures
3.1
8.5
53
219
WZC30
NOMESCO Finland
Teaching
4.6
8.5
30
77
M01AE02
ATC
naproxen; oral, rectal
2.8
8.5
105
660
J38.7
ICD-10 Finland
Other diseases of larynx
+∞
8.4
8
*
N02AX02
ATC
tramadol; systemic, rectal
2.8
8.2
65
312
J01AA02
ATC
doxycycline; systemic
3.2
8.1
130
948
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
14.0
8.0
13
10
R23
ICPC
Voice symptom/complaint
14.0
8.0
13
10
F32.9
ICD-10 Finland
Depressive episode, unspecified
7.1
8.0
19
30
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.9
7.9
33
99
N06AX16
ATC
venlafaxine; oral
5.0
7.9
25
57
R06.5
ICD-10 Finland
Mouth breathing
16.1
7.8
12
8
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
47.4
7.8
9
*
R06AE09
ATC
levocetirizine; oral
3.6
7.8
37
124
H25.1
ICD-10 Finland
Senile nuclear cataract
26.5
7.7
10
*
UDC00
NOMESCO Finland
Ear microscopy
5.7
7.6
21
41
J01DB01
ATC
cefalexin; oral
3.2
7.3
135
1032
R03BA02
ATC
budesonide; inhalant
3.5
7.2
35
119
R06.2
ICD-10 Finland
Wheezing
9.5
7.2
14
16
J37.0
ICD-10 Finland
Chronic laryngitis
12.9
7.2
12
10
N02BE01
ATC
paracetamol; systemic, rectal
3.1
7.2
134
1020
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.2
7.1
27
74
SPAT1263
SPAT
Sampling
2.6
7.1
67
350
H03AA01
ATC
levothyroxine sodium; systemic
3.1
7.1
42
164
N06AX11
ATC
mirtazapine; oral
2.9
7.1
48
206
F51.0
ICD-10 Finland
Nonorganic insomnia
3.7
7.0
31
98
R42
ICD-10 Finland
Dizziness and giddiness
3.4
6.9
34
117
UKC02
NOMESCO Finland
Cystoscopy
4.6
6.9
23
56
J01DA01
ATC
[U] cefalexin; systemic
2.5
6.8
105
704
HMAK
NOMESCO Finland
NA
3.5
6.8
32
106
J01FA10
ATC
azithromycin; systemic
2.5
6.8
108
735
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.5
6.8
19
38
R49.09
ICD-10 Finland
Unspecified dysphonia
23.7
6.8
9
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
6.7
63
324
J02AC01
ATC
fluconazole; systemic
2.4
6.7
80
468
N06AA09
ATC
amitriptyline; systemic
5.2
6.7
20
43
N05BA04
ATC
oxazepam; oral
3.3
6.7
34
120
WX402
NOMESCO Finland
General anaesthesia
3.4
6.6
33
115
SCA03
NOMESCO Finland
Preventive oral health care, extensive
6.5
6.5
16
27
M01AE03
ATC
ketoprofen; systemic, rectal
2.5
6.5
60
307
R01AD01
ATC
beclometasone; nasal
3.2
6.5
36
135
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.8
6.4
47
209
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
11.7
6.4
11
10
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
7.6
6.4
14
20
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.8
6.3
15
24
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.4
6.3
22
56
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
6.3
6
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
+∞
6.3
6
*
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
+∞
6.3
6
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
+∞
6.3
6
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
+∞
6.3
6
*
A10BH01
ATC
sitagliptin; oral
+∞
6.3
6
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
6.2
83
508
SPAT1312
SPAT
General health counselling
2.5
6.2
57
289
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.0
6.2
16
29
B01AA03
ATC
warfarin; systemic
6.5
6.2
15
25
A02BA02
ATC
ranitidine; systemic
3.5
6.1
28
91
R03AK07
ATC
formoterol and budesonide; inhalant
2.9
6.1
40
165
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.3
6.0
15
26

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
54
65
11.65
44.17
3.0
2.7
1.2
1.2
mmol/l
0.40
48
53
28
11
30.21
40.70
2.1
3.5
3.7
4.2
e9/l
0.44
28
11
101
275
7.47
39.58
4.7
2.8
—
—
—
0
0
28
12
27.68
39.44
2.1
3.6
56.1
54.1
%
0.17
28
12
57
99
8.12
34.06
4.0
3.1
—
—
—
0
0
95
279
6.37
33.24
4.5
4.5
—
—
—
0
0
60
143
5.91
25.55
1.8
1.4
405.4
440.2
pmol/l
0.50
44
129
81
258
5.04
24.42
9.8
2.8
1.1
1.0
inr
1.58
64
77
85
291
4.80
23.19
4.0
2.7
0.0
0.0
estimate
0.50
54
111
18
10
19.99
22.40
3.0
3.5
4.9
4.8
kpa
—
18
10
18
10
19.99
22.40
3.0
3.5
8.6
10.4
kpa
—
18
10
37
62
7.33
22.28
4.4
3.1
0.4
0.0
%
—
7
14
37
62
7.33
22.28
4.2
3.1
0.3
0.0
%
—
7
13
51
122
5.52
21.30
1.5
1.3
—
—
—
0
0
37
65
6.98
21.27
4.4
3.0
1.1
0.6
%
—
7
17
73
236
4.64
21.13
3.4
2.2
—
—
—
0
0
36
63
6.96
20.75
3.3
2.9
1.8
0.2
%
—
5
12
79
275
4.46
20.67
3.8
1.7
12.5
24.3
ng/l
0.91
44
117
150
849
6.99
20.26
5.0
2.5
9.0
8.5
mm/h
0.18
145
791
103
442
4.32
20.06
5.3
4.2
0.7
0.7
%
0.13
98
412
108
490
4.24
19.20
5.5
4.2
0.5
0.5
e9/l
0.74
103
428
103
466
4.02
18.07
5.5
4.1
2.6
3.1
%
1.37
98
432
108
506
4.05
17.97
2.8
3.0
6.1
6.0
mmol/l
0.55
102
461
65
223
4.08
16.84
3.0
3.1
7.4
7.4
ph
0.16
42
43
69
258
3.80
15.62
2.4
1.9
54.2
62.9
u/l
0.84
60
233
14
10
15.15
15.22
2.3
3.8
—
—
—
0
0
81
348
3.51
14.65
4.0
2.1
—
—
—
0
0
105
533
3.49
14.44
3.4
2.4
83.2
87.2
ug/l
0.16
97
509
22
36
6.86
13.29
3.5
9.8
24.2
24.6
mmol/l
0.22
22
36
60
226
3.54
13.13
2.0
2.1
302.1
9708.9
umol/l
1.54
54
212
77
341
3.28
12.94
3.7
4.2
1.2
1.2
mmol/l
0.97
67
309
73
314
3.30
12.86
3.4
4.0
36.4
37.1
g/l
0.65
65
291
131
800
3.67
12.66
6.9
5.2
69.0
75.1
u/l
1.36
124
746
93
468
3.15
12.43
4.2
5.5
8.8
11.8
umol/l
3.04
86
449
12
10
12.82
11.86
2.3
3.6
—
—
—
0
0
144
959
4.08
11.63
5.3
3.3
15.1
14.4
pmol/l
2.97
135
887
37
109
4.05
11.47
1.4
1.2
—
—
—
0
0
103
572
3.00
11.18
5.8
3.3
0.0
0.0
estimate
0.00
57
111
103
576
2.96
10.97
4.6
2.4
0.0
0.0
estimate
0.00
56
112
15
20
8.12
10.73
2.3
1.1
1.2
1.2
g/l
0.02
15
20
101
565
2.91
10.65
4.7
2.4
0.0
0.0
estimate
0.00
56
108
35
105
3.93
10.54
1.9
1.4
1566.4
1124.0
nmol/l
1.62
26
78
102
577
2.89
10.48
2.9
2.1
—
—
—
0
0
15
8
20.36
10.46
2.5
2.4
—
—
—
0
0
15
8
20.36
10.46
1.0
1.1
—
—
—
0
0
14
6
25.21
10.42
1.5
1.3
2.1
1.2
mmol/l
—
14
6
123
772
3.08
10.35
4.2
2.2
—
—
—
0
0
48
182
3.27
10.12
2.5
1.5
3.0
2.6
mg/l
0.84
43
145
105
611
2.84
10.09
7.6
7.4
3.7
3.7
e9/l
0.01
100
529
13
6
23.27
9.50
1.5
1.2
91.5
91.6
%
—
13
6
155
1159
4.41
8.93
5.9
3.7
1.7
2.8
mu/l
0.55
144
1077
54
244
2.77
8.17
1.4
1.2
1.1
1.2
u/ml
0.02
31
68
48
210
2.78
7.68
1.3
1.1
1.8
6.2
u/ml
0.63
31
85
30
102
3.35
7.40
2.8
1.2
106.0
39.2
ug/g
0.68
21
78
36
146
2.85
6.56
2.6
1.9
40.2
741.0
mg/l
0.58
22
71
49
236
2.51
6.36
2.0
1.6
0.5
0.6
mg/l
0.72
33
184
72
413
2.28
6.29
4.0
2.3
—
—
—
0
0
29
107
3.06
6.23
1.6
1.2
—
—
—
0
0
27
96
3.15
6.17
2.1
1.2
—
—
—
0
0
159
1297
3.99
6.16
15.6
6.9
13.6
21.4
mg/l
2.78
141
889
37
158
2.71
6.10
3.7
2.3
4.8
16.0
mg/mmol
1.48
21
82
10
16
6.57
6.02
1.1
1.3
—
—
—
0
0
13
28
4.94
5.84
1.4
3.0
—
—
—
0
0
39
176
2.57
5.75
2.7
1.9
8.6
7.9
mmol/l
0.31
31
153
10
17
6.18
5.69
1.1
2.9
—
—
—
0
0
144
1131
2.68
5.60
4.9
2.7
38.2
36.2
mmol/mol
3.28
129
1067
44
213
2.43
5.59
1.3
1.3
2.3
2.2
g/l
0.14
37
138
111
785
2.17
5.48
4.7
3.1
—
—
—
0
0
164
1438
4.02
5.16
14.7
6.6
—
—
—
0
0
12
27
4.70
5.12
1.4
2.4
—
—
—
0
0
9
9
10.47
5.09
1.8
1.7
—
—
—
0
0
43
218
2.30
4.87
1.3
1.1
9.4
18.9
iu/ml
0.78
16
63
9
11
8.56
4.62
1.8
1.6
24.3
24.8
mmol/l
—
9
11
7
5
14.50
4.61
2.4
1.6
2007.9
1850.0
ml
—
7
5
8
8
10.41
4.57
3.1
1.3
32.3
32.0
pg
—
8
8
101
720
1.98
4.52
4.8
3.2
—
29.2
—
0
6
45
241
2.17
4.44
3.4
2.4
—
—
—
0
0
48
265
2.13
4.38
3.6
2.4
36.2
85.2
e6/l
0.37
42
197
7
6
12.08
4.31
1.0
1.0
—
—
—
0
0
35
171
2.31
4.29
1.3
1.2
—
—
—
0
0
55
323
2.03
4.25
4.3
2.8
10.0
41.3
e6/l
1.20
48
209
78
523
1.90
4.07
1.7
1.9
—
—
—
0
0
149
1248
2.45
4.04
4.5
2.9
5.7
5.4
mmol/l
3.25
137
1173
17
60
3.03
3.92
1.3
1.3
—
—
—
0
0
25
109
2.51
3.91
1.3
1.3
—
—
—
0
0
23
97
2.58
3.85
2.3
1.1
—
—
—
0
0
31
163
2.10
3.16
1.6
1.2
22.7
21.3
nmol/l
0.16
26
135
11
34
3.39
3.11
1.2
1.1
1.2
1.3
u/ml
—
5
12
6
8
7.72
3.08
1.5
1.1
—
—
—
0
0
6
9
6.86
2.89
1.2
1.0
—
—
—
0
0
5
6
8.53
2.76
1.4
1.7
—
—
—
0
0
30
166
1.98
2.66
5.5
3.2
—
—
—
0
0
14
57
2.59
2.52
3.6
2.5
—
—
—
0
0
5
8
6.39
2.38
1.6
1.3
—
—
—
0
0
149
1321
1.96
2.37
4.3
3.2
1.6
1.6
mmol/l
0.19
136
1256
6
13
4.74
2.29
4.2
1.2
25.7
26.7
mmol/l
—
6
13
47
314
1.68
2.27
1.9
1.3
84.2
101.1
pmol/l
1.27
20
169
149
1327
1.92
2.24
4.3
3.2
4.7
5.0
mmol/l
3.49
135
1259
7
19
3.79
2.17
1.0
2.7
4.2
3.5
mmol/l
—
7
19
19
97
2.08
2.10
1.1
1.2
17.2
103.7
iu/ml
—
6
42
6
15
4.10
2.05
2.2
6.2
0.7
0.5
%
—
6
15
149
1340
1.84
1.99
4.5
3.4
2.8
3.0
mmol/l
2.20
136
1265
7
21
3.43
1.98
2.4
1.2
—
—
—
0
0
7
21
3.43
1.98
3.7
4.8
120.7
134.2
g/l
—
7
21
143
1273
1.73
1.95
3.9
2.9
1.2
1.2
mmol/l
0.03
130
1203
5
11
4.65
1.95
1.0
1.3
—
—
—
0
0
6
16
3.84
1.95
2.2
5.9
1.1
1.0
%
—
6
16
11
229
0.44
1.88
1.4
1.4
—
—
—
0
0
10
41
2.53
1.79
1.3
1.8
—
—
—
0
0
7
24
3.00
1.74
1.6
1.3
—
—
—
0
0
5
13
3.93
1.72
1.6
2.5
—
—
—
0
0
39
266
1.60
1.72
1.9
1.9
—
—
—
0
0
5
130
0.37
1.71
1.2
1.4
—
—
—
0
0
8
31
2.66
1.68
3.9
5.8
4.7
4.8
kpa
—
8
31
26
161
1.72
1.64
1.1
1.7
—
—
—
0
0
8
32
2.57
1.62
1.1
1.3
—
—
—
0
0
37
253
1.59
1.61
4.4
1.9
—
—
—
0
0
41
288
1.56
1.59
1.6
1.5
1.3
1.3
mmol/l
0.24
30
258
5
15
3.40
1.53
1.6
1.0
—
—
—
0
0
12
58
2.15
1.53
1.1
1.1
—
—
—
0
0
9
39
2.38
1.45
3.6
5.4
1.3
1.4
mmol/l
—
9
34
9
40
2.32
1.42
3.6
5.3
5.9
6.0
kpa
—
9
40
9
41
2.26
1.39
3.6
5.2
—
—
—
0
0
5
17
3.00
1.37
1.6
1.0
—
—
—
0
0
8
36
2.28
1.26
3.6
2.0
—
—
—
0
0
12
64
1.94
1.21
20.5
9.9
—
1.0
—
0
11
34
244
1.49
1.20
4.6
4.3
1.4
2.0
ug/l
1.21
28
221
5
20
2.54
1.16
1.2
1.1
—
—
—
0
0
7
30
2.39
1.13
1.7
1.1
—
—
—
0
0
7
30
2.39
1.13
2.7
2.4
—
—
—
0
0
8
41
2.00
1.10
1.1
1.2
—
—
—
0
0
12
67
1.85
1.07
1.5
1.1
—
—
—
0
0
12
69
1.79
0.99
1.7
1.2
—
—
—
0
0
6
119
0.49
0.98
2.3
1.6
—
—
—
0
0
7
37
1.93
0.95
1.9
1.2
—
—
—
0
0
18
119
1.57
0.92
1.9
1.6
—
—
—
0
0
18
121
1.54
0.87
1.9
1.6
—
—
—
0
0
6
31
1.97
0.85
1.3
1.2
—
—
—
0
0
8
46
1.77
0.84
1.5
1.5
—
—
—
0
0
15
99
1.56
0.78
1.2
2.5
5.7
6.0
umol/l
—
9
88
7
40
1.78
0.72
5.3
7.5
—
—
—
0
0
7
42
1.69
0.69
1.9
1.2
—
—
—
0
0
7
43
1.65
0.67
1.9
1.2
—
—
—
0
0
7
43
1.65
0.67
1.9
1.2
—
—
—
0
0
7
44
1.62
0.66
1.9
1.2
—
—
—
0
0
28
220
1.33
0.62
4.5
2.6
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
14
192
0.71
0.56
1.8
1.5
—
—
—
0
0
9
62
1.48
0.54
1.2
1.1
—
—
—
0
0
9
63
1.45
0.53
1.6
1.2
—
—
—
0
0
5
32
1.58
0.42
14.4
3.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
27.5
—
0
9
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
27
233
1.19
0.30
5.7
7.0
—
—
—
0
0
5
39
1.29
0.23
8.8
1.6
—
—
—
0
0
5
42
1.20
0.21
1.0
1.5
384.2
131.0
pmol/l
—
5
42
0
10
0.00
0.21
0.0
1.1
—
419.3
—
0
10
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
21
184
1.16
0.20
2.0
1.7
—
—
—
0
0
6
78
0.76
0.16
1.7
1.5
—
—
—
0
0
9
82
1.10
0.15
4.0
3.0
—
—
—
0
0
38
394
0.95
0.05
1.8
1.6
—
—
—
0
0
15
159
0.94
0.03
3.0
2.6
0.4
0.6
ug/l
—
8
100
22
228
0.96
0.02
1.7
1.7
—
—
—
0
0
132
1312
1.03
0.02
11.0
8.0
41.4
40.4
%
1.58
78
1072
32
322
0.99
0.00
3.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
76.3
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
7.0
—
722.8
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
6
64
0.94
0.00
3.5
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint TRACHEOBRONCHOMAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have TRACHEOBRONCHOMAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: TRACHEOBRONCHOMAL – Tracheo-bronchomalasia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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