No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
187 |
4. Check minimum number of eventsNone |
187 |
5. Include endpointsNone |
187 |
6. Filter based on genotype QC (FinnGen only) |
184 |
Control definitions (FinnGen only)
- Control exclude
- ASTHMA_COMORB
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J39
- Name in latin
- Alii morbi tractus respiratorii superioris specificati
Similar endpoints
↥List of similar endpoints to
Tracheo-bronchomalasia
based on the number of shared cases.
Similar with more cases:
- Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
- Other diseases of upper respiratory tract
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 959 | 617 | 340 |
| Only index persons | 905 | 596 | 309 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 49.42 | 48.58 | 51.04 |
| Only index persons | 49.18 | 48.54 | 50.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 184 | 132 | 52 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | 52.69 | 51.04 | 56.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 187
- Matched controls
- 1870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J39.8
ICD-10 Finland
Other specified diseases of upper respiratory tract
+∞
270.6
187
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
80.6
188.5
112
34
XG474
NOMESCO Finland
Exhalation nntrogen oxide
53.4
98.5
59
16
J45.9
ICD-10 Finland
Asthma, unspecified
14.5
74.4
91
115
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
46.2
70.4
43
12
R03AK08
ATC
formoterol and beclometasone; inhalant
23.7
57.0
44
24
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
25.4
50.0
37
18
R03BA08
ATC
ciclesonide; inhalant
10.7
41.0
52
65
J45.1
ICD-10 Finland
Nonallergic asthma
15.6
40.4
38
30
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.9
39.1
99
263
XQ800
NOMESCO Finland
Prick test
10.9
38.3
47
56
R06.0
ICD-10 Finland
Dyspnoea
6.8
35.6
77
174
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
+∞
33.3
31
*
R03AC02
ATC
salbutamol; inhalant
8.6
32.8
157
710
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
8.2
32.3
51
82
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
6.2
27.9
61
136
G47.3
ICD-10 Finland
Sleep apnoea
6.3
27.1
56
118
A02BC02
ATC
pantoprazole; systemic
6.0
25.2
149
737
J45
ICD-10 Finland
Asthma
7.7
25.1
40
64
R49.01
ICD-10 Finland
Functional dysphonia
27.4
25.0
34
15
H02AB06
ATC
prednisolone; systemic
4.6
24.0
111
449
C07AB07
ATC
bisoprolol; oral
4.8
23.8
79
248
A02BC05
ATC
esomeprazole; systemic
4.5
23.6
102
391
J39.9
ICD-10 Finland
Disease of upper respiratory tract, unspecified
136.8
23.2
24
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.5
23.0
56
136
SPAT1262
SPAT
Handing over of treatment supplies
9.8
22.5
28
33
R01AD12
ATC
fluticasone furoate; nasal
4.4
22.5
109
451
R05
ICD-10 Finland
Cough
4.7
22.2
71
215
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
9.1
21.9
29
37
R5140
NOMESCO Finland
Monitoring the use of the aid
8.3
21.0
30
42
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.6
21.0
29
39
R03BB04
ATC
tiotropium bromide; inhalant
8.7
20.5
28
37
R03DC03
ATC
montelukast; oral
4.7
20.1
59
166
I25.1
ICD-10 Finland
Atherosclerotic heart disease
117.6
20.0
21
*
103
Kela drug reimbursment
Diabetes, insulin-treated
+∞
19.1
18
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
19.1
18
*
Z01.8
ICD-10 Finland
Other specified special examinations
4.5
18.4
56
161
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.8
17.6
30
51
N03AX16
ATC
[U] pregabalin
4.4
17.4
55
162
SPAT1263
SPAT
Sampling
3.6
16.9
92
394
SPAT1249
SPAT
Treatment-related counselling outside office
3.6
16.7
92
396
R03BA05
ATC
fluticasone; inhalant
4.1
16.6
59
189
N06AX16
ATC
venlafaxine; oral
5.8
16.2
33
67
I48
ICD-10 Finland
Atrial fibrillation and flutter
93.1
15.8
17
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
26.1
15.5
21
9
UDC00
NOMESCO Finland
Ear microscopy
6.3
15.3
28
51
WZC30
NOMESCO Finland
Teaching
4.6
15.0
41
107
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.7
15.0
64
231
N06AX11
ATC
mirtazapine; oral
3.6
14.9
68
256
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
5.5
14.9
32
68
SPAT1301
SPAT
No procedures
3.6
14.8
67
251
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
14.8
14
*
J37.0
ICD-10 Finland
Chronic laryngitis
24.7
14.6
20
9
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
19.5
14.2
21
12
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
19.5
14.2
21
12
XX3DW
NOMESCO Finland
Time consuming IT work
4.7
14.1
37
93
N06AA09
ATC
amitriptyline; systemic
6.4
14.1
25
44
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.6
13.9
38
99
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
18.0
13.8
21
13
ZXE00
NOMESCO Finland
One hour or less
3.2
13.8
90
419
207
Kela drug reimbursment
Chronic arrhythmias
81.2
13.8
15
*
R51.80
ICD-10 Finland
Headache
4.1
13.7
45
135
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
6.4
13.6
24
42
UJF32
NOMESCO Finland
Coloscopy
3.9
13.2
47
149
UKC02
NOMESCO Finland
Cystoscopy
5.0
13.0
31
72
R01AD08
ATC
fluticasone; nasal
3.1
12.9
80
359
N06AX21
ATC
duloxetine; oral
5.5
12.8
27
56
R01AD58
ATC
fluticasone, combinations; nasal
3.2
12.8
72
305
WX780
NOMESCO Finland
Remote monitoring CPAP
14.6
12.8
21
16
J38.3
ICD-10 Finland
Other diseases of vocal cords
75.1
12.8
14
*
WX402
NOMESCO Finland
General anaesthesia
3.5
12.6
54
193
R03BA01
ATC
beclometasone; inhalant
4.0
12.5
41
122
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.1
12.4
124
722
F32.9
ICD-10 Finland
Depressive episode, unspecified
11.2
12.4
23
23
XKD00
NOMESCO Finland
Uroflowmetry
5.3
12.3
27
58
R03AK07
ATC
formoterol and budesonide; inhalant
3.4
12.3
58
220
A10BA02
ATC
metformin; oral
14.8
12.3
20
15
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.8
12.1
44
141
WX723
NOMESCO Finland
CPAP therapy
13.8
11.9
20
16
R06AE07
ATC
cetirizine; oral
2.9
11.9
104
559
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
32.4
11.8
15
5
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
32.4
11.8
15
5
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
24.8
11.8
16
7
AA1AD
NOMESCO Finland
CT of head and brain
4.0
11.7
38
112
N03AX12
ATC
[U] gabapentin; oral
4.1
11.7
37
107
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
11.6
11
*
R06AE09
ATC
levocetirizine; oral
3.6
11.4
44
146
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.6
11.3
44
147
J01FA09
ATC
clarithromycin; systemic
2.9
11.1
78
369
R07.4
ICD-10 Finland
Chest pain, unspecified
3.5
11.1
46
160
R06.5
ICD-10 Finland
Mouth breathing
16.8
11.1
17
11
J01.0
ICD-10 Finland
Acute maxillary sinusitis
3.0
11.0
64
273
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.8
11.0
27
64
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.1
11.0
20
36
M01AE02
ATC
naproxen; oral, rectal
3.0
11.0
131
819
N02AJ06
ATC
codeine and paracetamol; systemic
2.8
10.9
89
455
A02BC03
ATC
lansoprazole; oral
3.1
10.9
58
235
SPAT1058
SPAT
PEF monitoring instruction
5.8
10.9
21
40
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
10.8
78
374
J46
ICD-10 Finland
Status asthmaticus
63.7
10.8
12
*
N05BA04
ATC
oxazepam; oral
3.3
10.7
48
175
J02AC01
ATC
fluconazole; systemic
2.8
10.7
97
523
SPAT1312
SPAT
General health counselling
2.9
10.6
71
326
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
25.0
10.4
14
6
J31.0
ICD-10 Finland
Chronic rhinitis
4.5
10.4
27
67
T90
ICPC
Diabetes non-insulin dependent
10.0
10.3
20
22
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.3
10.3
22
46
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.7
10.2
82
414
N02AX02
ATC
tramadol; systemic, rectal
2.8
10.0
77
379
A02BC01
ATC
omeprazole; systemic
3.0
10.0
58
246
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.3
9.9
28
74
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
9.9
91
489
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.9
9.8
22
31
J01FA10
ATC
azithromycin; systemic
2.8
9.8
131
847
E66.01
ICD-10 Finland
Obesity due to excess calories
8.3
9.7
21
28
J01DB01
ATC
cefalexin; oral
4.0
9.7
165
1216
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
31.9
9.5
12
*
C01DA14
ATC
isosorbide mononitrate; oral
31.9
9.5
12
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
105.1
9.5
10
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.3
9.4
41
146
N06AB04
ATC
citalopram; systemic
3.8
9.4
31
92
N05AH04
ATC
quetiapine; oral
4.3
9.3
26
68
R06AX27
ATC
desloratadine; oral
2.7
9.3
74
368
R23
ICPC
Voice symptom/complaint
10.9
9.2
17
17
F51.0
ICD-10 Finland
Nonorganic insomnia
3.3
9.2
41
148
J01AA02
ATC
doxycycline; systemic
3.2
9.1
154
1104
R49.08
ICD-10 Finland
Other specified dysphonia
19.8
9.1
13
7
Z01.9
ICD-10 Finland
Special examination, unspecified
7.3
9.0
21
32
B01AF02
ATC
apixaban; oral
15.0
8.8
14
10
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
52.5
8.8
10
*
J01DA01
ATC
[U] cefalexin
2.6
8.7
125
816
M54.5
ICD-10 Finland
Low back pain
2.6
8.6
72
365
C07AB02
ATC
metoprolol; systemic
4.2
8.5
24
63
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
13.6
8.5
14
11
J38.7
ICD-10 Finland
Other diseases of larynx
94.1
8.5
9
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
94.1
8.5
9
*
H03AA01
ATC
levothyroxine sodium; systemic
2.8
8.4
52
226
A10BH01
ATC
sitagliptin; oral
+∞
8.4
8
*
AN1
HP
Coronary angiography
+∞
8.4
8
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
4.7
8.4
20
46
J01MA02
ATC
ciprofloxacin; systemic
2.6
8.4
65
317
R03BA02
ATC
budesonide; inhalant
3.0
8.3
42
163
D82
ICPC
Teeth/gum disease
2.5
8.3
86
480
R03AC13
ATC
formoterol; inhalant
8.8
8.3
17
21
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.3
8.3
35
122
G04BD12
ATC
mirabegron; oral
4.5
8.2
21
51
SPAT1377
SPAT
Polysomnography
12.5
8.2
14
12
XKC03
NOMESCO Finland
Water cystometry
18.2
8.2
12
7
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
35.0
8.2
10
*
J01FF01
ATC
clindamycin; systemic
2.7
8.1
54
243
R42
ICD-10 Finland
Dizziness and giddiness
3.1
8.1
38
141
R49.09
ICD-10 Finland
Unspecified dysphonia
23.2
8.1
11
5
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
8.1
69
351
A01AB04
ATC
amphotericin B; local oral
9.1
8.0
16
19
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
8.0
79
430
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
4.2
8.0
22
57
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.5
8.0
20
48
M01AE03
ATC
ketoprofen; systemic, rectal
2.5
7.9
73
385
UJF30
NOMESCO Finland
Ileoscopy through colon
4.7
7.9
19
44
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
8.0
7.9
17
23
SPAT1254
SPAT
Administration of medicine
4.0
7.9
24
67
N06AB03
ATC
fluoxetine; oral
4.3
7.9
21
53
HMAK, ,
NOMESCO Finland
3.1
7.8
36
132
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
7.8
77
418
I10
ICD-10 Finland
Essential (primary) hypertension
2.4
7.8
80
442
SPAT1153
SPAT
Removal of sutures
2.6
7.8
57
269
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
12.6
7.7
13
11
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.7
7.7
14
14
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.5
7.6
28
89
A01AB09
ATC
miconazole; local oral
4.8
7.6
18
41
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.4
7.6
20
50
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.6
7.5
54
252
J01FA06
ATC
roxithromycin; oral
2.4
7.5
79
440
I50.9
ICD-10 Finland
Heart failure, unspecified
14.1
7.5
12
9
E11
ICD-10 Finland
Type 2 diabetes mellitus
14.1
7.5
12
9
XF404
NOMESCO Finland
Ambulatory ECG
7.4
7.5
17
25
R00.2
ICD-10 Finland
Palpitations
4.2
7.5
21
55
TFP20
NOMESCO Finland
Cardiodefibrillation
+∞
7.3
7
*
B01AA03
ATC
warfarin; systemic
6.5
7.3
18
30
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
7.3
72
389
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
7.2
47
208
R01AD01
ATC
beclometasone; nasal
2.8
7.2
41
169
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
31.3
7.2
9
*
J32.4
ICD-10 Finland
Chronic pansinusitis
31.3
7.2
9
*
H25.1
ICD-10 Finland
Senile nuclear cataract
9.4
7.2
14
16
R03AC12
ATC
salmeterol; inhalant
7.5
7.2
16
23
SCA03
NOMESCO Finland
Preventive oral health care, extensive
5.9
7.1
19
35
M03BC51
ATC
orphenadrine, combinations; systemic
2.4
7.1
61
309
R01AD09
ATC
mometasone; nasal
2.3
7.0
101
638
N02BE01
ATC
paracetamol; systemic, rectal
3.4
7.0
166
1312
M79.6
ICD-10 Finland
Pain in limb
2.3
6.9
77
436
H02AB04
ATC
methylprednisolone; systemic
3.3
6.9
28
95
G44.2
ICD-10 Finland
Tension-type headache
3.1
6.9
31
112
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
6.9
34
130
E66.00
ICD-10 Finland
Metabolic syndrome
17.5
6.8
10
6
R02
ICPC
Shortness of breath/dyspnoea
3.9
6.8
21
59
A10BK03
ATC
empagliflozin; oral
41.6
6.8
8
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.4
6.8
26
85
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
8.3
6.7
14
18
C08CA01
ATC
amlodipine; oral
2.6
6.7
48
222
N02BF01
ATC
gabapentin; oral
4.1
6.7
19
50
M54.4
ICD-10 Finland
Lumbago with sciatica
2.8
6.7
37
150
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.0
6.7
20
55
J01MA12
ATC
levofloxacin; systemic
3.0
6.7
32
120
A02BA02
ATC
ranitidine; systemic
3.0
6.7
32
120
SPAT1310
SPAT
Counselling related to known health issue
2.4
6.6
58
295
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.1
6.6
29
103
N06AB10
ATC
escitalopram; oral
2.8
6.6
36
145
M03BC01
ATC
orphenadrine (citrate); systemic
2.5
6.6
50
238
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
6.6
31
115
M01AB55
ATC
diclofenac, combinations; oral
7.9
6.5
14
19
R06.2
ICD-10 Finland
Wheezing
7.9
6.5
14
19
M01AH05
ATC
etoricoxib; oral
2.3
6.5
126
888
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.9
6.5
17
31
M03BX02
ATC
tizanidine; oral
2.3
6.5
130
929
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
6.4
6.5
16
27
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
8.6
6.4
13
16
M01AC06
ATC
meloxicam; systemic, rectal
2.3
6.4
71
399
B01AC04
ATC
clopidogrel; oral
11.6
6.4
11
10
WZA00
NOMESCO Finland
Concise certificate
4.0
6.4
19
52
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
6.4
44
200
SPAT1240
SPAT
Therapeutic discussion
3.8
6.4
20
57
-1, ,
ICD-10 Finland
4.2
6.3
17
43
N05AX12
ATC
aripiprazole; systemic
+∞
6.3
6
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
+∞
6.3
6
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
+∞
6.3
6
*
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
+∞
6.3
6
*
H26.4
ICD-10 Finland
After-cataract
+∞
6.3
6
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
+∞
6.3
6
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
27.7
6.3
8
*
SPAT1238
SPAT
Brief therapy
27.7
6.3
8
*
Z01.2
ICD-10 Finland
Dental examination
2.2
6.2
94
596
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
3.5
6.2
22
68
JN3AD
NOMESCO Finland
Abdominal CT examination
3.6
6.2
21
63
R53
ICD-10 Finland
Malaise and fatigue
2.5
6.2
44
203
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
9.1
6.2
12
14
OAB50, ,
SPAT
13.1
6.2
10
8
Z2445
NOMESCO Finland
Psychologist
10.5
6.1
11
11
L04AX03
ATC
methotrexate; systemic
5.4
6.0
17
34
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
5.4
6.0
17
34
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
59
62
13.44
53.35
2.9
2.8
1.23
1.24
mmol/l
0.33
52
52
53
84
8.41
34.14
2.4
2.1
—
—
—
0
0
95
312
5.16
27.75
3.9
2.6
0.00
0.01
estimate
0.50
61
115
64
155
5.76
26.65
1.8
1.3
417.00
65000431.61
pmol/l
0.50
48
140
94
323
4.84
25.55
11.2
2.6
1.12
1.02
inr
1.57
70
92
87
295
4.64
23.75
3.7
1.6
12.06
16.30
ng/l
1.09
50
113
163
894
7.41
23.66
5.0
2.5
9.08
8.49
mm/h
0.29
158
835
30
11
32.13
23.09
2.1
3.6
3.58
4.40
e9/l
0.86
30
11
30
12
29.49
22.58
2.1
3.4
55.27
55.75
%
0.04
30
12
115
535
3.99
19.21
2.8
2.7
6.06
5.89
mmol/l
0.76
109
483
106
479
3.80
18.23
4.2
2.4
—
—
—
0
0
24
31
8.73
17.85
3.7
8.5
24.31
24.96
mmol/l
0.43
24
31
116
577
3.66
16.79
3.4
2.3
83.22
88.41
ug/l
0.21
108
551
74
280
3.72
16.33
2.3
2.0
53.37
66.92
u/l
1.21
64
258
79
321
3.53
15.49
3.3
4.0
36.33
37.04
g/l
0.66
70
297
83
355
3.41
14.89
3.7
3.9
1.21
1.23
mmol/l
1.28
74
327
101
490
3.31
14.65
4.1
5.8
9.08
11.56
umol/l
2.12
92
466
141
838
3.77
14.59
6.9
5.3
68.88
74.74
u/l
1.44
134
783
113
599
3.24
13.87
5.6
3.3
0.00
0.00
estimate
-0.00
64
115
158
1032
4.42
13.73
5.5
3.4
15.19
14.42
pmol/l
3.44
148
957
113
605
3.19
13.52
4.4
2.4
0.00
0.00
estimate
-0.00
63
115
62
233
3.48
13.49
2.0
2.1
303.63
7821.43
umol/l
1.29
56
215
111
593
3.15
13.25
4.6
2.4
0.00
0.00
estimate
-0.00
64
120
87
406
3.14
13.16
4.7
4.6
1.22
1.23
mmol/l
0.14
50
346
54
190
3.59
12.96
2.5
1.4
3.15
2.57
mg/l
1.22
49
151
19
11
19.05
12.81
2.9
4.0
4.87
4.80
kpa
0.11
19
11
87
416
3.04
12.46
2.3
1.8
79.31
77.13
nmol/l
0.27
78
384
115
649
3.00
12.06
7.7
7.4
3.68
3.70
e9/l
0.03
109
567
15
5
32.39
11.84
1.5
1.2
1.99
1.26
mmol/l
—
15
5
36
102
4.13
11.71
1.9
1.4
1566.42
1157.96
nmol/l
1.43
26
76
41
130
3.76
11.38
2.8
1.4
564.88
255.02
ng/l
0.89
31
108
169
1236
4.82
10.74
6.1
3.8
1.74
2.76
mu/l
0.54
157
1151
72
338
2.84
10.30
3.2
2.3
—
—
—
0
0
18
19
10.35
9.51
1.6
1.8
—
—
—
0
0
58
259
2.80
8.95
1.4
1.2
1.06
2.87
u/ml
0.49
34
67
52
220
2.89
8.87
1.3
1.1
1.75
8.39
u/ml
0.90
32
85
54
241
2.74
8.28
1.9
1.6
0.44
0.56
mg/l
0.75
36
180
169
1309
4.02
8.23
14.1
5.9
85.78
86.99
ml/min/173m2
0.39
159
1044
174
1390
4.62
7.74
15.7
6.8
13.66
20.83
mg/l
2.75
155
947
38
149
2.95
7.34
3.4
2.2
4.82
14.17
mg/mmol
1.24
21
79
53
253
2.53
6.98
3.2
2.3
0.06
0.42
e6/l
1.53
48
189
155
1188
2.78
6.75
4.7
2.6
38.19
35.98
mmol/mol
4.05
137
1121
178
1530
4.39
6.47
10.0
6.1
25.84
24.54
u/l
0.46
172
1481
48
227
2.50
6.40
1.3
1.2
11.62
22.82
iu/ml
0.79
19
68
128
919
2.25
6.15
3.2
2.2
36.28
32.38
u/l
0.62
118
882
59
321
2.22
5.66
1.5
1.6
—
—
—
0
0
9
7
13.42
5.64
1.0
1.6
—
—
—
0
0
10
10
10.48
5.60
1.7
1.6
24.91
24.52
mmol/l
—
10
10
16
34
5.05
5.45
1.6
1.3
—
—
—
0
0
162
1323
2.68
5.24
4.4
2.8
5.71
5.42
mmol/l
3.81
147
1243
11
16
7.23
5.03
1.9
1.7
—
—
—
0
0
27
111
2.67
4.72
2.1
1.4
—
—
—
0
0
13
27
5.09
4.59
4.3
1.4
—
—
—
0
0
14
32
4.64
4.54
1.5
1.1
—
—
—
0
0
5
209
0.22
4.14
1.4
1.6
—
—
—
0
0
7
9
8.02
3.59
2.0
1.1
—
—
—
0
0
48
283
1.94
3.55
1.7
1.5
1.39
1.26
mmol/l
0.51
33
250
9
18
5.19
3.41
1.6
3.7
7.51
6.84
g/l
—
9
18
9
18
5.19
3.41
1.6
3.7
—
—
—
0
0
9
18
5.19
3.41
1.6
3.7
3.61
3.36
g/l
—
9
18
33
173
2.10
3.36
1.7
1.2
22.55
20.74
nmol/l
0.23
28
146
13
39
3.50
3.30
1.2
1.1
1.04
1.08
u/ml
—
6
22
6
7
8.80
3.28
1.0
1.1
—
—
—
0
0
9
19
4.92
3.28
1.1
1.1
—
—
—
0
0
7
11
6.56
3.21
1.0
1.2
—
—
—
0
0
8
16
5.17
3.08
1.6
3.1
12.05
10.12
g/l
—
8
16
162
1412
2.10
3.06
4.3
3.1
1.54
1.58
mmol/l
0.46
147
1349
182
1696
3.73
3.02
22.3
10.1
41.07
40.54
%
1.25
182
1602
5
5
10.22
2.99
1.4
1.0
—
—
—
0
0
51
324
1.79
2.95
1.8
1.3
83.31
98.96
pmol/l
1.29
22
172
8
17
4.86
2.95
1.0
1.4
—
—
—
0
0
8
17
4.86
2.95
1.0
1.3
—
—
—
0
0
8
17
4.86
2.95
1.6
3.8
2.60
2.74
g/l
—
8
17
6
9
6.84
2.89
1.0
1.2
—
—
—
0
0
133
1100
1.72
2.85
4.4
3.4
—
—
—
0
0
162
1422
2.04
2.85
4.3
3.1
4.71
5.00
mmol/l
3.91
146
1354
7
14
5.15
2.75
3.0
6.6
1.07
0.97
%
—
7
14
6
10
6.16
2.72
1.2
1.0
—
—
—
0
0
16
69
2.44
2.56
2.5
1.4
—
—
—
0
0
6
11
5.59
2.56
1.0
1.1
—
—
—
0
0
162
1437
1.95
2.53
4.5
3.3
2.83
3.05
mmol/l
2.74
147
1365
22
111
2.11
2.48
1.1
1.2
17.17
139.44
iu/ml
—
6
48
7
17
4.23
2.38
1.7
3.5
0.00
0.00
g/l
—
7
17
7
17
4.23
2.38
1.7
3.8
0.00
2.55
g/l
—
7
17
155
1364
1.80
2.38
3.8
2.8
1.16
1.15
mmol/l
0.07
140
1293
11
40
2.86
2.32
1.5
1.6
—
—
—
0
0
6
13
4.73
2.29
1.2
1.0
—
—
—
0
0
13
54
2.51
2.25
5.5
5.3
103.62
105.46
mmol/l
0.37
13
54
15
67
2.35
2.24
2.4
1.3
—
—
—
0
0
7
19
3.78
2.17
1.0
2.7
4.16
3.54
mmol/l
—
7
19
6
14
4.39
2.17
5.5
3.0
51.43
33.01
%
—
6
14
15
69
2.28
2.11
1.3
1.4
—
—
—
0
0
6
15
4.10
2.05
4.2
1.9
25.73
26.32
mmol/l
—
6
15
10
39
2.65
1.97
4.0
5.6
1.38
1.72
mmol/l
—
10
33
6
16
3.84
1.95
1.8
2.8
37.38
41.71
g/l
—
6
16
5
13
3.92
1.72
1.6
1.3
0.44
0.52
nmol/l
—
5
13
36
240
1.62
1.72
4.8
4.0
1.39
1.96
ug/l
1.42
30
213
10
40
2.58
1.69
4.0
5.5
5.88
5.98
kpa
—
10
40
5
14
3.64
1.62
2.0
3.1
0.00
0.00
g/l
—
5
14
5
14
3.64
1.62
2.0
3.1
0.00
0.00
g/l
—
5
14
6
20
3.06
1.59
5.8
3.6
22.78
24.44
mmol/l
—
6
20
9
37
2.50
1.50
1.9
1.5
—
—
—
0
0
9
45
2.05
1.25
5.3
4.1
4.88
5.31
kpa
—
9
40
17
101
1.75
1.24
1.2
2.4
5.33
5.67
umol/l
—
10
85
5
19
2.67
1.22
6.2
4.6
0.54
0.68
%
—
5
19
5
19
2.67
1.22
6.2
4.6
1.00
1.04
%
—
5
19
5
20
2.54
1.16
1.0
1.4
—
—
—
0
0
5
20
2.54
1.16
1.0
1.2
—
—
—
0
0
8
40
2.04
1.13
2.1
1.7
—
—
—
0
0
5
22
2.31
1.04
1.8
1.3
—
—
—
0
0
6
32
1.90
0.82
1.0
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
—
—
0
0
5
24
2.11
0.75
3.0
8.0
23.40
23.87
mmol/l
—
5
24
67
585
1.23
0.63
2.8
2.2
—
—
—
0
0
40
330
1.27
0.62
1.6
1.5
—
—
—
0
0
8
52
1.56
0.60
1.3
1.6
—
—
—
0
0
6
36
1.69
0.57
1.2
1.6
—
—
—
0
0
6
36
1.69
0.57
1.2
1.1
—
—
—
0
0
26
208
1.29
0.51
2.2
1.9
—
—
—
0
0
9
65
1.40
0.51
1.6
1.7
—
—
—
0
0
9
65
1.40
0.51
2.0
1.6
—
—
—
0
0
11
78
1.44
0.44
1.1
1.0
—
—
—
0
0
5
31
1.63
0.43
3.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
14
109
1.31
0.34
7.5
3.9
—
—
—
0
0
11
143
0.75
0.33
1.3
1.5
—
—
—
0
0
11
139
0.78
0.28
1.3
1.6
—
—
—
0
0
27
240
1.15
0.21
2.3
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
7
59
1.19
0.18
1.1
2.2
—
—
—
0
0
23
205
1.14
0.18
3.7
3.5
17.09
20.11
%
0.51
12
86
5
44
1.14
0.10
1.0
1.5
384.20
128.30
pmol/l
—
5
44
10
114
0.87
0.10
1.3
1.5
—
—
—
0
0
13
122
1.07
0.03
3.7
3.4
34.25
33.67
%
—
8
83
24
246
0.97
0.00
2.0
1.8
—
—
—
0
0
16
155
1.04
0.00
2.9
2.4
0.44
0.65
ug/l
—
8
94
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.8
—
0.19
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint TRACHEOBRONCHOMAL and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have TRACHEOBRONCHOMAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: TRACHEOBRONCHOMAL – Tracheo-bronchomalasia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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