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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Lower jaw bone

CD2_BENIGN_BONE_LOWER_JAW_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D16.50&, D16.51&
  • Hospital discharge: ICD-9 2131
  • Hospital discharge: ICD-8 21300
  • Cause of death: ICD-10 D16.50&, D16.51&
  • Cause of death: ICD-9 2131
  • Cause of death: ICD-8 21300

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 148 95 53
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 40.91 41.21 40.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
140
Matched controls
1400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.50
ICD-10 Finland
Benign tumor of the mandibular bone or cartilage
+∞
58.5
52
*
D16.51
ICD-10 Finland
Benign tumor of the mandibular bone with urpsrung in teeth
+∞
56.1
50
*
21300
ICD-8 Finland
Benign neoplasm of bone and cartilage, Mandibulae (detibus inclusis)
+∞
24.7
23
*
EDA10
NOMESCO Finland
Biopsy of mandible
+∞
22.5
21
*
EFA10
NOMESCO Finland
Excision of lesion of jaws
+∞
20.3
19
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
5.6
18.9
70
211
EFA50
NOMESCO Finland
Excision of cyst of jaws
77.0
18.2
20
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
17.2
17.7
28
20
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
12.6
17.6
32
32
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
54.4
16.5
19
*
2131A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Lower jaw bone
+∞
15.9
15
*
D16.5
ICD-10 Finland
Benign neoplasm: Lower jaw bone
+∞
14.8
14
*
SAA03
NOMESCO Finland
Extended examination of mouth
3.9
13.4
82
369
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
11.6
11
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
7.4
10.8
26
42
EBA10
NOMESCO Finland
Surgical removal of tooth
5.3
9.8
31
71
EBB10
NOMESCO Finland
Insertion of dental implant
32.5
9.6
12
*
H02AB02
ATC
dexamethasone; systemic
26.0
9.1
12
5
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.5
9.0
27
58
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
35.6
8.2
10
*
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
6.5
7.9
20
35
115
Kela drug reimbursment
Breast cancer
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
SBB10
NOMESCO Finland
Teeth copy
5.8
6.9
19
37
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
7.1
6.9
16
25
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
6.6
37
142
SXC03
NOMESCO Finland
Other oral or dental procedure
28.0
6.3
8
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
+∞
6.3
6
*
4332
FHL
Lower jaw resection or tumor removal
+∞
6.3
6
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
6.3
6
*
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
6.3
6
*
K09.29
ICD-10 Finland
Cyst of jaw traumatic
+∞
6.3
6
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
30
5.86
8.41
1.1
1.4
—
—
—
0
0
69
367
2.65
7.72
2.2
1.5
—
—
—
0
0
18
50
3.96
5.97
2.6
1.4
4.4
2.6
ug/l
0.87
12
34
22
74
3.32
5.53
2.3
2.2
0.2
0.2
g/l
0.67
22
68
55
303
2.30
5.31
2.3
2.1
—
—
—
0
0
24
92
2.92
4.85
1.2
1.1
—
—
—
0
0
25
111
2.51
3.81
3.4
5.4
1.0
1.1
mmol/l
0.76
25
101
30
148
2.29
3.63
1.4
1.2
—
—
—
0
0
10
29
3.63
3.10
1.3
1.6
0.2
2.0
ug/l
—
10
24
27
137
2.19
3.05
2.9
2.4
0.9
0.8
mmol/l
0.56
27
126
16
71
2.41
2.44
9.7
5.1
0.0
0.2
%
—
7
13
56
397
1.66
2.23
3.6
3.4
30.2
29.4
ng/l
0.03
34
249
40
261
1.73
2.15
2.4
2.0
3.0
2.7
mg/l
0.26
31
222
8
25
3.32
2.13
3.0
2.0
24.5
22.9
mmol/l
—
8
19
37
238
1.74
2.09
4.4
3.7
—
—
—
0
0
5
10
5.13
2.08
1.2
1.3
—
—
—
0
0
15
72
2.21
1.94
10.3
4.9
0.0
0.0
%
—
7
12
16
79
2.15
1.94
9.8
4.7
0.4
0.6
%
—
7
18
38
252
1.68
1.92
5.7
4.8
—
—
—
0
0
34
223
1.68
1.78
1.5
1.8
461.6
467.6
pmol/l
0.03
28
185
13
61
2.24
1.77
11.0
4.5
22.3
25.1
mmol/l
2.54
13
61
53
390
1.56
1.75
8.0
6.9
1.2
1.1
inr
0.24
18
109
22
128
1.84
1.72
1.4
1.5
—
—
—
0
0
7
25
2.89
1.67
1.1
1.2
—
—
—
0
0
7
26
2.77
1.60
2.9
2.1
29.6
35.6
umol/l
—
7
20
6
20
3.08
1.60
3.0
1.8
—
—
—
0
0
24
148
1.74
1.56
1.4
2.0
—
—
—
0
0
14
72
2.04
1.54
10.6
4.9
0.0
0.5
%
—
7
11
17
96
1.87
1.46
1.4
1.3
—
—
—
0
0
6
23
2.67
1.38
1.3
2.7
—
—
—
0
0
62
496
1.43
1.30
11.0
7.6
0.0
0.0
e9/l
0.00
54
394
135
1259
1.82
1.25
16.7
12.0
74.2
74.1
umol/l
0.02
135
1259
41
307
1.46
1.21
1.3
1.5
—
—
—
0
0
42
316
1.46
1.21
2.1
2.0
144.0
171.6
u/l
0.35
42
303
104
921
1.43
1.18
4.1
4.0
14.5
14.7
pmol/l
0.27
95
850
55
439
1.40
1.14
7.4
4.8
1.2
1.2
mmol/l
0.55
50
399
5
22
2.32
1.04
3.2
2.0
—
—
—
0
0
8
145
0.53
0.99
1.6
1.9
—
—
—
0
0
38
291
1.41
0.99
2.4
2.8
—
—
—
0
0
5
23
2.21
0.99
3.2
1.8
—
—
—
0
0
88
772
1.35
0.97
4.1
3.5
—
—
—
0
0
35
265
1.42
0.97
3.6
2.4
354.1
6148.9
umol/l
1.28
29
238
18
118
1.60
0.96
1.6
1.8
—
—
—
0
0
73
624
1.34
0.95
8.3
6.9
4.3
4.1
e9/l
0.19
63
548
13
78
1.73
0.95
1.2
1.4
—
—
—
0
0
6
28
2.19
0.92
1.0
1.1
—
—
—
0
0
42
332
1.37
0.91
3.3
1.9
2.3
2.4
mmol/l
0.09
36
281
29
216
1.43
0.88
2.4
2.4
587.3
549.8
mosm/kgh2o
0.27
24
178
34
262
1.39
0.85
4.4
3.5
—
—
—
0
0
37
290
1.37
0.84
3.8
2.9
7.4
7.4
ph
0.31
12
48
6
32
1.91
0.82
1.3
1.1
—
—
—
0
0
48
393
1.33
0.82
3.3
3.5
14.8
97.7
e6/l
2.85
35
273
44
356
1.34
0.82
4.7
5.6
—
—
—
0
0
13
83
1.62
0.78
1.7
2.4
52.2
67.2
e9/l
—
7
62
9
54
1.71
0.76
15.8
7.7
95.1
93.2
%
—
9
54
5
24
2.12
0.75
3.6
2.3
8.6
8.2
kpa
—
5
24
5
24
2.12
0.75
3.6
2.3
4.6
4.9
kpa
—
5
24
9
55
1.68
0.75
15.8
7.5
0.6
0.7
%
—
9
55
9
56
1.65
0.74
15.8
7.4
1.0
1.5
%
—
9
56
38
307
1.32
0.71
3.0
3.1
86.3
72.9
mg/l
0.10
24
187
32
252
1.34
0.71
1.6
1.8
0.5
1.0
mg/l
1.85
24
189
10
155
0.62
0.70
1.1
1.5
—
—
—
0
0
7
43
1.66
0.68
1.0
1.1
—
—
—
0
0
40
328
1.30
0.67
3.7
4.0
14.4
11.3
mg/mmol
0.11
26
201
53
451
1.27
0.67
3.7
3.3
—
—
—
0
0
7
44
1.62
0.66
15.3
8.5
—
—
—
0
0
65
569
1.25
0.65
4.0
3.5
0.0
0.0
estimate
0.00
19
102
66
581
1.25
0.62
3.9
3.5
0.0
0.0
estimate
0.00
17
99
41
342
1.28
0.61
3.3
3.2
6.8
7.4
mmol/l
0.36
36
292
19
141
1.40
0.60
1.5
1.4
—
—
—
0
0
0
22
0.00
0.60
0.0
3.7
—
23.2
—
0
13
6
35
1.74
0.58
1.5
1.0
—
—
—
0
0
5
87
0.56
0.58
1.2
1.3
—
41.7
—
0
8
36
297
1.28
0.58
4.9
3.6
0.0
0.0
estimate
0.00
17
94
65
575
1.23
0.58
5.2
4.9
0.0
0.0
estimate
0.00
17
99
131
1254
1.39
0.57
13.8
10.4
—
—
—
0
0
36
298
1.27
0.56
2.4
2.9
0.2
0.3
e6/l
0.41
30
217
6
38
1.60
0.55
1.0
1.3
—
—
—
0
0
40
338
1.25
0.53
2.7
2.9
10.8
233.8
e6/l
0.61
35
258
9
64
1.43
0.52
3.0
2.4
—
—
—
0
0
57
502
1.22
0.52
7.1
5.5
0.5
0.7
%
1.15
47
469
138
1337
1.48
0.50
22.4
16.1
90.7
90.5
fl
0.16
138
1313
138
1337
1.48
0.50
22.4
16.1
249.4
255.3
e9/l
0.54
138
1302
25
201
1.29
0.49
1.2
1.3
0.8
9.8
u/ml
—
8
80
37
314
1.24
0.47
2.7
3.3
—
—
—
0
0
138
1339
1.45
0.47
22.4
16.1
4.5
4.5
e12/l
1.41
138
1298
138
1339
1.45
0.47
22.4
16.0
30.1
30.2
pg
0.12
138
1315
5
85
0.57
0.47
1.2
1.3
—
—
—
0
0
138
1340
1.44
0.46
22.5
16.1
6.4
6.5
e9/l
0.22
138
1300
58
518
1.20
0.45
6.8
5.4
2.6
2.9
%
0.53
48
486
138
1342
1.42
0.43
22.8
16.1
133.4
136.8
g/l
2.18
138
1316
58
522
1.18
0.41
7.2
5.6
9.0
8.2
%
0.83
49
492
9
66
1.39
0.39
1.3
1.2
—
—
—
0
0
12
89
1.38
0.39
2.8
3.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
59
534
1.17
0.39
7.1
5.4
27.5
28.7
%
0.30
50
504
92
864
1.17
0.38
4.0
4.0
13.2
9.9
mm/h
1.11
86
792
9
71
1.28
0.37
2.6
1.2
—
—
—
0
0
63
578
1.16
0.34
7.0
5.5
0.2
0.2
e9/l
0.22
51
517
6
45
1.35
0.34
1.7
1.6
—
—
—
0
0
123
1187
1.21
0.34
5.0
4.6
2.7
2.8
mmol/l
0.58
115
1102
34
297
1.19
0.33
4.4
4.0
—
—
—
0
0
116
1115
1.19
0.33
4.1
3.8
1.3
1.3
mmol/l
0.13
108
1031
6
47
1.29
0.32
2.0
1.7
—
—
—
0
0
17
138
1.26
0.32
1.2
1.3
—
—
—
0
0
7
54
1.31
0.31
2.6
2.8
2.0
1.4
%
—
7
54
38
339
1.16
0.29
2.7
3.0
—
—
—
0
0
120
1160
1.18
0.29
4.5
4.2
1.5
1.5
mmol/l
0.34
112
1078
32
283
1.17
0.27
1.4
1.3
0.4
1.0
u/ml
2.74
14
67
113
1091
1.15
0.26
15.9
12.0
39.6
40.5
%
0.75
83
831
9
73
1.25
0.26
2.1
2.7
—
—
—
0
0
115
1112
1.15
0.26
5.0
4.7
1.7
1.8
mu/l
0.24
109
1031
9
76
1.20
0.25
1.1
1.8
—
—
—
0
0
49
451
1.13
0.24
2.2
1.9
105.6
98.9
pmol/l
0.59
30
210
17
143
1.21
0.24
32.6
21.7
—
1.3
—
0
21
57
530
1.12
0.24
7.1
5.2
58.7
57.1
%
0.41
49
500
118
1145
1.15
0.24
4.8
4.2
6.0
5.9
mmol/l
0.35
110
1050
122
1187
1.16
0.23
15.5
10.7
27.0
20.7
mg/l
0.95
106
857
10
79
1.29
0.23
19.3
7.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
48
1.26
0.20
3.2
5.0
—
—
—
0
0
120
1170
1.14
0.20
4.5
4.2
4.6
4.7
mmol/l
0.86
111
1092
112
1090
1.11
0.18
6.4
5.4
40.0
39.3
mmol/mol
0.35
107
1030
7
62
1.14
0.17
1.1
1.1
—
—
—
0
0
12
101
1.20
0.17
2.7
3.5
—
—
—
0
0
30
275
1.11
0.16
7.5
4.5
—
—
—
0
0
9
80
1.13
0.15
1.1
1.3
—
—
—
0
0
102
995
1.08
0.13
18.7
13.4
13.8
13.5
%
1.52
102
976
22
201
1.11
0.12
1.3
1.3
105.8
25.8
iu/ml
—
9
70
10
86
1.17
0.11
5.9
2.6
—
—
—
0
0
80
778
1.06
0.10
3.6
4.4
—
—
—
0
0
5
45
1.11
0.10
2.2
2.4
—
—
—
0
0
5
48
1.04
0.09
6.4
1.9
—
—
—
0
0
11
97
1.14
0.09
6.3
4.1
—
—
—
0
0
13
143
0.90
0.07
1.5
1.7
—
—
—
0
0
7
81
0.86
0.07
4.4
4.4
109.6
77.1
ng/l
—
7
71
9
104
0.86
0.06
1.0
1.1
—
—
—
0
0
20
189
1.07
0.05
1.6
1.6
1403.3
1225.8
nmol/l
0.29
15
140
24
251
0.95
0.04
1.8
1.9
—
—
—
0
0
46
450
1.03
0.03
2.8
2.8
—
—
—
0
0
55
559
0.97
0.02
7.7
5.3
0.0
0.0
e9/l
0.51
48
493
20
206
0.97
0.00
1.5
1.6
—
—
—
0
0
56
557
1.01
0.00
7.5
5.3
0.5
0.6
e9/l
0.01
49
493
11
108
1.02
0.00
1.3
1.3
—
—
—
0
0
25
252
0.99
0.00
1.5
1.3
2.5
2.4
g/l
0.14
16
141
10
95
1.06
0.00
6.8
4.1
-1.4
2.1
mmol/l
—
10
73
57
569
1.00
0.00
7.5
5.3
1.6
1.8
e9/l
1.32
51
513
0
9
0.00
0.00
0.0
10.2
—
0.6
—
0
9
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.87
0.00
2.6
3.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
2475.0
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
5
53
0.94
0.00
9.0
1.8
—
—
—
0
0
5
52
0.96
0.00
6.4
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
258.4
—
0
5
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
37.4
—
0
8
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
5
53
0.94
0.00
6.6
1.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_BONE_LOWER_JAW_EXALLC – Benign neoplasm: Lower jaw bone

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).