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This is a non-core endpoint: only basic statistics are computed.

Benign neoplasm: Heart

Endpoint Browser

CD2_BENIGN_HEART_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D15.1&
  • Hospital discharge: ICD-9 — 2127
  • Cause of death: ICD-10 — D15.1&
  • Cause of death: ICD-9 — 2127

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D15
Name in latin
Neoplasma benignum cordis

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 118 72 46
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 61.96 61.07 63.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
106
Matched controls
1061
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D15.1
ICD-10 Finland
Benign neoplasm: Heart
+∞
147.1
104
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
73.8
62
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
35.2
39.4
52
28
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
37.7
33.0
42
18
WX872
NOMESCO Finland
Intensive care
20.2
21.7
33
23
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
9.0
19.2
46
83
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.4
16.7
56
158
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.8
15.5
45
103
AJX
HP
Other surgery on the heart or aorta
+∞
13.8
13
*
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
79.7
12.9
14
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.2
12.9
49
150
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
12.1
68
304
B01AA03
ATC
warfarin; systemic
4.9
11.2
43
130
AMX
HP
Other surgical procedure for a demanding cardiac patient
+∞
10.6
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
5.3
10.2
34
87
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.8
9.6
19
23
B01AB05
ATC
enoxaparin; parenteral
3.9
9.2
49
193
WX408
NOMESCO Finland
General anesthesy, balanced
3.8
8.8
45
171
115
Kela drug reimbursment
Breast cancer
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
11.4
8.3
15
15
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.8
8.1
41
152
C07AB07
ATC
bisoprolol; oral
3.3
7.8
69
383
C03CA01
ATC
furosemide; systemic
3.3
7.4
47
204
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.2
7.4
30
91
51
HP
Other heart surgery
+∞
7.4
7
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
7.4
7
*
130
Kela drug reimbursment
Malignant tumour
+∞
7.4
7
*
L02BG04
ATC
letrozole; oral
42.9
6.9
8
*
XF404
NOMESCO Finland
Ambulatory ECG
5.0
6.6
21
50
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
6.3
6
*
D15.9
ICD-10 Finland
Benign neoplasm: Intrathoracic organ, unspecified
+∞
6.3
6
*
AN1
HP
Coronary angiography
4.0
6.2
25
75

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
17
14.81
21.79
1.2
1.2
—
—
—
0
0
89
377
6.54
19.79
11.8
8.3
1.3
1.3
inr
0.06
19
100
32
58
7.20
18.11
1.3
1.0
—
—
—
0
0
62
247
4.18
13.44
2.3
1.9
—
—
—
0
0
53
227
3.42
9.66
5.7
3.2
—
—
—
0
0
19
44
4.96
8.02
2.3
1.5
3.7
2.7
ug/l
0.42
13
32
87
572
2.98
6.55
9.7
4.0
6.8
6.9
mmol/l
0.19
81
529
30
115
3.16
6.25
14.4
5.9
13.5
11.6
kpa
0.84
30
108
30
115
3.16
6.25
14.4
5.9
5.4
5.2
kpa
0.39
30
107
30
117
3.10
6.05
14.4
5.8
2.0
1.6
mmol/l
0.18
25
88
28
105
3.19
6.03
15.0
5.9
94.9
95.9
%
0.17
28
99
46
228
2.67
5.96
3.6
2.0
2.9
3.0
mg/l
0.04
37
194
51
269
2.58
5.79
4.0
3.2
7.4
7.4
ph
—
8
40
69
425
2.50
5.57
12.9
5.1
1.2
1.2
mmol/l
2.69
64
384
50
267
2.51
5.47
2.1
1.6
—
—
—
0
0
76
513
2.35
4.68
11.6
6.0
4.2
4.3
e9/l
0.18
61
445
61
381
2.24
4.46
3.9
2.7
98.3
110.6
ug/l
0.26
56
353
19
68
3.14
4.36
9.8
4.5
—
—
—
0
0
65
426
2.17
4.12
6.9
4.8
2.9
3.0
%
0.06
59
395
69
466
2.16
4.01
7.0
3.4
10.3
11.3
umol/l
0.62
64
434
49
295
2.13
3.78
7.5
5.1
—
—
—
0
0
18
69
2.90
3.67
15.2
6.1
26.1
24.2
mmol/l
0.94
18
64
20
83
2.70
3.53
16.0
6.6
—
—
—
0
0
57
371
2.04
3.52
5.5
3.6
34.4
35.5
g/l
0.68
49
348
60
398
2.03
3.51
6.4
3.7
73.9
32.2
ng/l
1.23
44
280
28
139
2.33
3.42
41.0
21.3
1.6
1.3
inr
—
5
19
45
271
2.07
3.41
4.1
2.2
2.3
2.4
mmol/l
0.17
36
221
8
14
6.04
3.40
1.5
1.4
—
—
—
0
0
16
60
2.93
3.39
7.8
2.7
127.2
129.1
g/l
0.12
16
60
68
480
1.98
3.26
6.7
5.0
0.2
0.2
e9/l
1.41
53
420
91
716
2.18
3.19
4.9
4.0
21.0
11.4
mm/h
3.16
85
649
9
20
4.78
3.18
4.7
2.9
—
—
—
0
0
45
280
1.98
3.07
4.9
3.0
—
—
—
0
0
66
469
1.92
3.03
6.7
4.8
1.8
2.0
e9/l
0.87
53
410
65
461
1.91
2.98
6.7
4.7
0.6
0.6
e9/l
0.03
50
392
36
209
2.04
2.96
6.9
5.0
—
—
—
0
0
14
53
2.86
2.91
23.4
5.6
—
—
—
0
0
65
464
1.89
2.90
6.7
4.7
0.0
0.0
e9/l
0.12
50
397
41
254
1.94
2.79
4.0
2.7
0.8
0.6
e6/l
0.18
29
183
78
600
1.89
2.66
6.1
4.0
—
54.2
—
0
12
39
242
1.91
2.62
4.1
2.5
—
—
—
0
0
21
103
2.26
2.61
7.7
3.4
—
—
—
0
0
7
16
4.58
2.51
2.3
2.3
71.6
65.7
%
—
7
16
14
60
2.51
2.32
1.4
1.3
—
—
—
0
0
35
218
1.86
2.30
1.4
1.3
—
—
—
0
0
41
271
1.79
2.21
7.1
3.9
—
—
—
0
0
85
693
1.81
2.18
6.0
3.7
—
—
—
0
0
9
32
2.96
2.05
8.2
4.4
4.1
3.8
mmol/l
—
9
27
80
649
1.72
2.00
5.2
4.0
—
—
—
0
0
21
115
2.00
1.99
1.8
1.4
360.0
656.8
titre
—
9
31
41
279
1.72
1.97
4.1
2.7
40.0
51.4
e6/l
0.16
30
205
103
905
2.09
1.93
4.9
4.6
1.9
1.9
mu/l
0.00
93
815
22
125
1.93
1.88
1.4
1.2
—
—
—
0
0
16
82
2.10
1.80
2.6
2.4
75.6
68.5
e9/l
—
8
64
46
331
1.64
1.77
4.7
3.2
49.6
89.9
e6/l
0.47
33
225
6
18
3.45
1.77
1.5
1.9
—
—
—
0
0
106
951
2.13
1.71
4.8
4.7
6.0
6.0
mmol/l
0.16
94
863
53
400
1.59
1.66
13.6
7.7
0.0
0.0
e9/l
0.00
39
308
25
155
1.78
1.64
3.1
2.0
2.5
2.4
mmol/l
0.80
19
124
29
188
1.72
1.63
1.6
1.3
3.3
2.5
g/l
0.65
18
104
53
403
1.57
1.59
2.1
1.9
101.4
96.2
pmol/l
0.31
34
191
7
27
2.69
1.54
1.4
1.6
—
—
—
0
0
10
46
2.28
1.44
7.9
2.5
28.3
24.6
mmol/l
—
10
46
27
178
1.67
1.43
3.6
2.4
542.5
530.1
mosm/kgh2o
0.11
22
145
107
977
2.02
1.41
25.8
11.3
27.7
22.7
mg/l
0.93
98
737
13
68
2.02
1.39
1.4
1.4
—
—
—
0
0
86
746
1.56
1.33
3.4
3.7
15.0
15.0
pmol/l
0.09
77
675
20
124
1.74
1.31
1.7
1.6
—
—
—
0
0
5
18
2.85
1.30
1.0
1.2
—
—
—
0
0
8
39
2.13
1.18
15.8
4.8
—
—
—
0
0
25
170
1.60
1.17
1.1
1.3
148.8
43.2
iu/ml
—
5
59
7
31
2.34
1.12
1.7
1.1
—
—
—
0
0
5
21
2.44
1.10
7.8
3.4
—
—
—
0
0
9
46
2.03
1.06
8.0
2.3
0.7
0.6
%
—
9
46
9
48
1.95
1.03
8.0
2.2
1.1
1.1
%
—
9
48
31
229
1.48
1.01
4.2
3.4
—
—
—
0
0
18
119
1.60
0.95
1.2
1.8
—
—
—
0
0
14
87
1.69
0.92
1.6
1.5
—
—
—
0
0
10
56
1.86
0.91
4.7
3.8
25.5
24.5
mmol/l
—
10
50
109
1030
1.76
0.86
29.2
13.5
77.2
77.4
umol/l
0.03
109
1030
8
46
1.79
0.84
1.0
1.5
—
—
—
0
0
23
166
1.48
0.84
1.2
1.2
22.7
10.9
u/ml
—
5
60
8
47
1.75
0.82
6.1
4.3
—
—
—
0
0
100
928
1.51
0.82
5.7
6.3
39.3
40.8
mmol/mol
1.06
90
865
107
1010
1.64
0.78
32.3
14.2
4.0
4.0
mmol/l
0.04
107
987
5
24
2.13
0.75
1.0
1.2
—
—
—
0
0
10
60
1.73
0.74
4.1
3.4
1.2
1.2
mmol/l
—
10
52
25
189
1.41
0.72
5.1
4.2
—
—
—
0
0
26
331
0.72
0.70
3.4
3.1
—
—
—
0
0
98
917
1.41
0.65
4.3
4.2
1.2
1.3
mmol/l
0.84
90
832
5
29
1.76
0.64
1.0
1.1
—
—
—
0
0
5
30
1.70
0.62
1.0
1.1
—
—
—
0
0
12
82
1.52
0.57
1.0
1.3
—
—
—
0
0
6
37
1.65
0.56
16.2
11.9
—
—
—
0
0
11
74
1.54
0.55
1.3
1.4
—
—
—
0
0
25
199
1.33
0.54
1.5
1.8
371.6
443.7
pmol/l
1.01
17
155
100
947
1.37
0.54
4.8
4.6
1.4
1.5
mmol/l
2.11
93
868
53
467
1.24
0.52
4.8
3.5
0.0
0.0
estimate
0.00
11
69
106
1015
1.44
0.51
24.1
11.3
—
—
—
0
0
7
48
1.49
0.48
3.4
3.9
—
—
—
0
0
5
33
1.54
0.42
1.0
1.1
—
—
—
0
0
5
35
1.45
0.40
1.0
1.3
—
—
—
0
0
9
66
1.39
0.39
8.1
3.1
—
—
—
0
0
21
253
0.79
0.38
5.4
3.1
—
—
—
0
0
100
960
1.27
0.36
4.8
4.7
4.4
4.6
mmol/l
1.51
92
890
51
461
1.19
0.36
4.8
3.5
0.0
0.0
estimate
0.00
11
77
26
220
1.23
0.36
1.7
1.4
1.4
2.3
u/ml
—
6
60
51
463
1.18
0.34
6.3
4.7
0.0
0.0
estimate
0.00
11
74
102
984
1.27
0.33
5.6
5.3
2.6
2.7
mmol/l
0.80
94
901
91
871
1.20
0.30
29.0
12.9
39.2
39.7
%
0.30
67
607
7
57
1.24
0.29
1.3
2.1
5.9
3.6
e9/l
—
7
40
21
178
1.22
0.29
1.8
1.7
1008.7
1237.1
nmol/l
0.62
16
136
9
73
1.25
0.26
6.0
3.4
—
—
—
0
0
34
305
1.16
0.26
2.6
2.0
49.4
56.3
u/l
1.01
28
276
11
87
1.29
0.25
1.1
1.5
—
—
—
0
0
12
98
1.25
0.22
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
5
66
0.75
0.17
1.2
1.5
—
—
—
0
0
6
76
0.78
0.16
1.0
1.4
—
—
—
0
0
39
364
1.11
0.16
3.9
3.2
—
—
—
0
0
9
79
1.15
0.15
2.6
3.9
—
—
—
0
0
31
287
1.11
0.14
4.7
3.8
2.2
2.1
ug/l
0.02
25
258
12
103
1.18
0.14
1.7
1.3
—
—
—
0
0
110
1083
1.23
0.14
37.3
17.1
90.9
90.9
fl
0.02
110
1066
110
1083
1.23
0.14
37.3
17.1
29.9
30.2
pg
1.09
110
1066
110
1083
1.23
0.14
37.4
17.2
4.3
4.5
e12/l
3.15
110
1045
110
1083
1.23
0.14
37.5
17.2
6.9
6.7
e9/l
0.46
110
1050
110
1083
1.23
0.14
37.4
17.2
258.1
251.8
e9/l
0.38
110
1052
110
1083
1.23
0.14
38.0
17.3
127.6
135.4
g/l
6.46
110
1064
28
261
1.10
0.11
1.6
1.7
1.3
1.3
mmol/l
0.18
23
217
13
115
1.15
0.11
2.1
1.7
—
—
—
0
0
24
258
0.91
0.10
6.6
3.7
0.0
0.0
estimate
0.00
11
71
30
317
0.93
0.09
2.6
3.3
2004.4
252.9
mg/l
0.41
20
207
7
66
1.06
0.08
4.6
2.4
—
—
—
0
0
33
339
0.96
0.02
3.2
4.2
16.7
8.7
mg/mmol
0.26
22
212
12
113
1.07
0.02
1.2
1.4
—
—
—
0
0
11
116
0.94
0.01
2.4
2.1
119.2
124.7
ug/g
0.04
11
94
17
164
1.04
0.00
3.1
2.6
2.2
0.8
ug/l
0.66
12
115
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
4.1
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
10.3
—
0
6
6
61
0.98
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_HEART_EXALLC – Benign neoplasm: Heart

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).