This is a non-core endpoint: only basic statistics are computed.
Malignant neoplasm of bone and articular cartilage of limbs
C3_BONE_CARTILAGE_LIMBS
bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
156 |
4. Check minimum number of eventsNone |
156 |
5. Include endpointsNone |
156 |
6. Filter based on genotype QC (FinnGen only) |
150 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of bone and articular cartilage of limbs
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of bone and articular cartilage
- Malignant neoplasm of bone and articular cartilage of limbs, including Hilmo
- Solid cancers, helper endpoint
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 150 | 64 | 86 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.04 |
| Median age at first event (years) | 34.71 | 33.93 | 35.30 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 156
- Matched controls
- 1560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
277.7
78.2
74
5
NF3AA
NOMESCO Finland
Femur X-ray examination
52.3
75.1
45
12
130
Kela drug reimbursment
Malignant tumour
+∞
71.5
63
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
58.0
52
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
52.0
47
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
21.0
44.1
36
22
N02AA05
ATC
oxycodone; systemic
9.7
40.8
62
99
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
19.5
40.4
34
22
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
39.2
36
*
GD1AD
NOMESCO Finland
Thorax CT examination
17.2
35.9
32
23
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
35.8
33
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
33.6
31
*
JN4AD
NOMESCO Finland
Body CT examination
13.3
32.5
34
32
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
32.4
30
*
L03AA02
ATC
filgrastim; parenteral
386.0
32.1
31
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
8.0
31.9
55
99
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
31.3
29
*
JN4BD
NOMESCO Finland
Extensive body CT
12.4
30.2
33
33
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
30.2
28
*
A04AA01
ATC
ondansetron; systemic, rectal
38.5
28.8
36
12
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.5
28.2
35
42
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
28.0
26
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
28.0
26
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
11.1
26.5
31
34
B01AB10
ATC
tinzaparin; parenteral
9.6
25.7
34
44
H02AB02
ATC
dexamethasone; systemic
67.6
25.0
28
5
A03FA01
ATC
metoclopramide; systemic, rectal
6.8
24.7
48
96
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
24.6
23
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
23.5
22
*
ZXE20
NOMESCO Finland
More than three and less than five hours
6.4
23.4
48
101
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.4
23.3
104
423
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
22.4
21
*
WX402
NOMESCO Finland
General anaesthesia
5.8
22.3
52
123
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.1
21.6
29
38
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
49.1
21.2
25
6
L03AA13
ATC
pegfilgrastim; parenteral
240.8
21.1
21
*
B01AB05
ATC
enoxaparin; parenteral
4.8
20.6
73
243
R4110
NOMESCO Finland
Physiotherapy
4.7
20.0
73
248
TPX10
NOMESCO Finland
Implantation of vascular injection port
26.9
19.9
27
12
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
19.6
66
210
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
18.1
17
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
18.1
17
*
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
202.0
17.9
18
*
A04AA02
ATC
granisetron; systemic, transdermal
202.0
17.9
18
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
17.0
16
*
Z51.5
ICD-10 Finland
Palliative care
18.1
16.9
26
17
WW500
NOMESCO Finland
Blood transfusion
21.5
16.6
24
13
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
15.9
15
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.6
15.9
35
77
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
42.9
15.8
19
5
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
177.0
15.8
16
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
24.0
15.1
21
10
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
15.0
47
138
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
88.7
14.9
16
*
N03AX16
ATC
[U] pregabalin
4.0
14.8
57
195
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.9
14.6
63
233
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.6
14.4
22
33
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.2
14.4
26
25
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
33.6
14.2
18
6
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.7
13
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
13.7
13
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
13.7
13
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
28.8
13.7
18
7
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
16.2
12.7
20
14
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
12.7
12
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
12.7
12
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
+∞
11.6
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
11.6
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.6
11
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
129.1
11.6
12
*
ZXA05
NOMESCO Finland
Left side
3.3
11.2
58
235
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
117.6
10.6
11
*
TPX15
NOMESCO Finland
Removal of vascular injection port
117.6
10.6
11
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
117.6
10.6
11
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
10.5
10
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
+∞
10.5
10
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.5
10
*
NF1AA
NOMESCO Finland
Hip X-ray examination
5.1
10.2
23
51
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
43.1
10.1
12
*
NB6AA
NOMESCO Finland
Humerus X-ray examination
12.6
9.8
17
15
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
9.8
66
309
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
9.7
28
76
ZX120
NOMESCO Finland
Intravenous
4.6
9.7
25
62
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
5.2
9.6
21
45
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.4
9.6
20
41
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
106.2
9.5
10
*
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
106.2
9.5
10
*
NF3AD
NOMESCO Finland
Femur CT
106.2
9.5
10
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
106.2
9.5
10
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
9.5
9
*
A04AD12
ATC
aprepitant; systemic
+∞
9.5
9
*
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
+∞
9.5
9
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
9.5
9
*
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
9.5
9
*
9101
FHL
Bone biopsy
+∞
9.5
9
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
9.5
9
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
9.5
9
*
J04AB02
ATC
rifampicin; systemic
39.2
9.1
11
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.2
8.9
26
71
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
17.6
8.7
13
8
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
17.6
8.7
13
8
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
95.0
8.5
9
*
WF002
NOMESCO Finland
Radical radiotherapy
95.0
8.5
9
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
8.4
8
*
NFA20
NOMESCO Finland
Exploration of hip joint or femur
+∞
8.4
8
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
+∞
8.4
8
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
8.4
8
*
L71
ICPC
Malignant neoplasm musculoskeletal
+∞
8.4
8
*
159
Kela drug reimbursment
Pazopanib
+∞
8.4
8
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
8.4
8
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.6
8.3
21
51
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
12.7
8.3
14
12
NG1AD
NOMESCO Finland
Knee CT examination
12.7
8.3
14
12
XX3DW
NOMESCO Finland
Time consuming IT work
6.8
8.2
20
33
N02AX02
ATC
tramadol; systemic, rectal
2.6
8.2
76
412
J01MA12
ATC
levofloxacin; systemic
3.2
8.2
39
148
J01FF01
ATC
clindamycin; systemic
2.9
8.1
48
206
WZC30
NOMESCO Finland
Teaching
3.6
8.0
29
92
ZXE00
NOMESCO Finland
One hour or less
2.6
7.9
73
393
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.5
7.8
20
49
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
47.4
7.8
9
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
47.4
7.8
9
*
NGQ20
NOMESCO Finland
Amputation of lower leg
47.4
7.8
9
*
R4120
NOMESCO Finland
Occupational therapy
4.7
7.7
19
45
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.7
7.7
19
45
JN4CD
NOMESCO Finland
Very extensive body CT
19.6
7.7
11
6
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
19.6
7.7
11
6
NFQ20
NOMESCO Finland
Amputation of femur
26.5
7.7
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.6
7.6
70
374
2392A
ICD-9 Finland
Neoplasm of unspecified nature, Bone, soft tissue and skin
83.9
7.5
8
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
10.1
7.5
14
15
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
7.4
61
309
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.2
7.3
19
34
C40.10
ICD-10 Finland
Malignant tumor of the upper limb's short bones without histology
+∞
7.3
7
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
7.3
7
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.3
7
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.3
7
*
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
+∞
7.3
7
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
12.9
7.2
12
10
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
8.2
7.1
15
20
N02BE01
ATC
paracetamol; systemic, rectal
4.6
7.0
144
1130
XW000
NOMESCO Finland
Bone marrow biopsy
10.0
6.9
13
14
ZXD05
NOMESCO Finland
Urgent procedure
2.5
6.9
58
295
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
6.8
53
260
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.4
6.5
17
42
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
72.7
6.5
7
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
72.7
6.5
7
*
L28
ICPC
Limited function/disability (L)
2.9
6.5
36
148
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
6.4
37
155
SPAT1229
SPAT
Assessment of need for aid
4.3
6.4
17
43
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
19.0
6.3
9
5
ZXA00
NOMESCO Finland
Right side
2.6
6.3
48
231
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.1
6.3
18
48
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
NK1AT
NOMESCO Finland
Muscle biopsy with ultrasound guidance
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
C40.0
ICD-10 Finland
Malignant neoplasm: Scapula and long bones of upper limb
+∞
6.3
6
*
C40.23
ICD-10 Finland
Ewing's sarcoma in the long bones of the lower extremity
+∞
6.3
6
*
NGB99
NOMESCO Finland
Other primary prosthetic replacement of knee joint, other or unspecified
+∞
6.3
6
*
343
Kela drug reimbursment
Pazopanib
+∞
6.3
6
*
NGR40
NOMESCO Finland
Extensive excision of tumor of knee or lower leg with repair
+∞
6.3
6
*
NK6AT
NOMESCO Finland
Bone biopsy with ultrasound guidance
+∞
6.3
6
*
C40.12
ICD-10 Finland
Chondrosarcoma of the short bones of the upper extremity
+∞
6.3
6
*
WX1DG
NOMESCO Finland
Very extensive total body MRI with high intensity magnet
+∞
6.3
6
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
6.3
6
*
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
+∞
6.3
6
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
6.5
6.2
15
25
WX002
NOMESCO Finland
Sedation and analgesia
2.8
6.2
37
158
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
74
230
5.22
23.20
5.7
2.1
—
—
—
0
0
103
465
4.58
18.95
19.6
8.0
1.21
1.21
mmol/l
0.08
93
419
44
105
5.44
18.38
7.9
2.8
240.23
230.11
u/l
0.30
44
100
96
424
4.29
17.91
11.0
4.8
34.56
36.29
g/l
2.38
90
400
16
0
+∞
16.98
31.9
0.0
0.37
—
umol/l
—
16
0
100
469
4.15
16.80
5.0
2.5
—
—
—
0
0
106
518
4.26
16.77
22.1
8.2
1.21
1.21
mmol/l
0.46
90
457
80
343
3.73
14.90
9.7
2.3
2.34
2.36
mmol/l
0.62
74
292
25
44
6.58
14.18
2.2
1.4
2.19
3.16
ug/l
1.60
17
31
39
109
4.44
13.17
2.4
1.7
—
—
—
0
0
39
112
4.31
12.68
2.3
1.6
—
—
—
0
0
39
114
4.23
12.37
11.4
12.7
5.23
5.13
kpa
0.36
39
109
47
158
3.83
12.27
2.6
1.7
—
—
—
0
0
38
112
4.16
11.89
11.7
12.8
0.54
0.87
mmol/l
0.28
33
98
112
657
3.50
11.66
29.4
6.7
3.76
4.22
e9/l
1.14
99
549
20
19
11.89
11.15
1.7
1.3
—
—
—
0
0
27
67
4.66
10.46
14.4
10.9
1.23
1.41
%
0.64
27
67
27
67
4.66
10.46
14.5
10.9
0.95
0.71
%
1.67
27
67
37
130
3.42
8.81
28.4
7.2
104.51
105.05
mmol/l
0.23
37
130
17
19
9.89
8.79
1.5
1.2
—
—
—
0
0
17
19
9.89
8.79
1.5
1.4
—
—
—
0
0
13
8
17.57
8.72
1.2
1.1
—
—
—
0
0
14
13
11.70
7.97
1.4
1.2
—
—
—
0
0
21
54
4.34
7.72
2.5
1.6
—
—
—
0
0
11
7
16.77
7.34
1.4
1.3
—
—
—
0
0
27
87
3.54
7.28
46.7
11.5
24.67
24.54
mmol/l
0.08
27
87
16
23
7.62
7.21
1.4
1.4
—
—
—
0
0
84
499
2.48
7.19
21.1
15.1
1.17
1.38
inr
1.35
19
143
70
397
2.38
6.48
4.7
3.5
—
—
—
0
0
17
32
5.83
6.37
2.6
3.8
—
—
—
0
0
12
14
9.18
6.18
1.2
1.1
—
—
—
0
0
10
8
13.24
6.17
1.6
1.5
—
—
—
0
0
10
8
13.24
6.17
1.6
1.5
—
—
—
0
0
120
876
2.60
6.08
5.6
4.2
14.79
10.04
mm/h
2.54
114
795
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
30
5.82
6.04
14.9
2.7
0.27
0.30
u/ml
—
9
16
12
15
8.56
5.96
1.5
1.3
—
—
—
0
0
12
15
8.56
5.96
1.5
1.3
—
—
—
0
0
24
83
3.24
5.76
4.8
3.2
—
—
—
0
0
55
293
2.35
5.75
3.3
2.5
6667.56
8236.42
umol/l
0.08
50
267
21
67
3.47
5.71
1.7
1.6
—
—
—
0
0
104
725
2.30
5.64
4.9
4.2
—
1058.67
—
0
12
57
322
2.21
5.09
3.7
3.3
0.25
0.25
e6/l
0.01
41
236
9
11
8.60
4.62
1.1
1.0
—
—
—
0
0
8
8
10.46
4.57
1.1
1.3
—
—
—
0
0
8
10
8.36
4.11
1.1
1.2
—
—
—
0
0
12
27
4.72
4.03
1.5
1.6
—
—
—
0
0
22
89
2.71
4.01
3.1
3.3
0.19
0.21
g/l
0.47
22
81
21
84
2.73
3.91
3.7
5.6
88.91
79.83
ng/l
0.17
21
77
7
8
9.09
3.81
8.0
2.8
—
—
—
0
0
130
1068
2.30
3.78
41.2
13.9
15.20
14.58
%
0.63
130
1048
33
167
2.24
3.75
2.9
2.9
12.22
14.29
umol/l
0.74
33
155
7
10
7.27
3.40
1.1
1.2
—
—
—
0
0
10
23
4.57
3.37
2.0
2.3
—
—
—
0
0
27
133
2.25
3.26
12.9
6.0
—
—
—
0
0
52
327
1.89
3.25
4.4
3.1
1563.77
1142.99
ng/l
0.25
47
272
131
1105
2.16
3.16
25.3
9.8
89.15
84.66
ml/min/173m2
1.01
115
871
18
75
2.58
3.10
2.5
1.6
86.75
74.33
ml/min/173m2
—
8
24
29
151
2.13
3.05
3.2
2.9
2.35
2.32
g/l
0.08
29
139
7
12
6.05
3.05
1.1
1.2
—
—
—
0
0
74
535
1.73
2.84
4.9
3.5
0.00
0.00
estimate
-0.00
15
106
7
14
5.18
2.76
1.0
1.1
—
—
—
0
0
39
237
1.86
2.66
3.7
3.8
39.03
302.84
ng/l
1.30
34
186
12
42
3.01
2.61
1.7
1.2
—
—
—
0
0
73
539
1.67
2.51
6.5
4.9
0.00
0.00
estimate
-0.00
15
97
140
1242
2.24
2.48
35.7
11.6
29.97
21.92
mg/l
1.72
127
903
11
38
3.04
2.47
6.0
3.0
213.27
185.63
%
0.50
11
38
145
1306
2.56
2.46
22.9
8.2
29.31
26.35
u/l
0.72
140
1246
8
22
3.77
2.40
1.6
1.2
—
—
—
0
0
8
22
3.77
2.40
1.6
1.2
—
—
—
0
0
7
17
4.26
2.39
1.4
1.0
—
—
—
0
0
21
107
2.11
2.34
8.6
5.8
5.08
4.96
kpa
0.44
21
100
73
548
1.62
2.30
5.1
3.6
0.00
0.00
estimate
-0.00
15
97
8
24
3.46
2.21
1.5
1.4
—
—
—
0
0
7
20
3.61
2.08
4.0
4.0
60.29
56.70
%
—
7
20
6
15
4.11
2.06
2.8
1.5
3.21
7.78
u/ml
—
6
15
7
21
3.44
1.99
1.3
1.3
—
—
—
0
0
13
58
2.35
1.97
48.9
2.8
0.66
0.66
%
0.00
13
58
63
471
1.57
1.94
2.5
2.7
79.10
76.32
nmol/l
0.34
56
410
32
202
1.73
1.91
3.2
2.9
1.66
1.01
e6/l
0.54
14
112
13
59
2.31
1.90
48.9
2.8
1.34
1.25
%
0.17
13
59
19
102
1.98
1.86
8.6
6.0
1.15
1.31
mmol/l
0.07
19
73
5
12
4.27
1.83
1.0
1.2
—
—
—
0
0
8
29
2.85
1.82
3.6
1.5
—
—
—
0
0
30
189
1.73
1.80
4.0
3.0
2.95
2.42
e6/l
0.14
11
99
40
279
1.58
1.63
2.2
2.5
2.76
2.79
mg/l
0.03
33
237
149
1408
2.30
1.53
56.2
16.6
37.68
40.97
%
6.67
141
1323
37
257
1.58
1.53
4.1
1.8
2.07
1.36
mg/l
0.57
31
190
55
423
1.46
1.41
5.3
3.5
—
—
—
0
0
18
105
1.81
1.40
2.2
2.1
11.60
14.87
nmol/l
0.63
13
99
22
137
1.71
1.38
46.5
4.4
6.01
5.63
kpa
1.63
22
131
6
23
2.67
1.38
1.7
1.2
—
—
—
0
0
12
63
1.98
1.26
1.5
1.5
—
—
—
0
0
38
277
1.49
1.26
6.2
3.8
0.00
0.00
estimate
-0.00
15
96
8
37
2.22
1.23
2.9
1.8
—
—
—
0
0
55
433
1.42
1.23
5.1
3.7
22.79
56.70
ng/l
1.90
46
287
19
120
1.66
1.15
48.8
4.3
4.26
4.91
kpa
1.00
19
113
8
40
2.05
1.14
2.9
1.9
—
—
—
0
0
7
32
2.24
1.09
1.0
1.2
—
—
—
0
0
12
200
0.57
1.08
1.8
2.3
—
—
—
0
0
52
419
1.36
0.99
4.0
3.8
2.06
2.10
ug/l
0.05
46
369
11
181
0.58
0.95
1.9
2.2
—
—
—
0
0
18
123
1.52
0.82
4.6
2.1
335.00
352.08
nmol/l
0.16
18
114
99
893
1.30
0.80
5.2
3.6
14.84
14.63
pmol/l
0.33
90
808
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
0
22
0.00
0.60
0.0
1.1
—
8.84
—
0
16
118
1115
1.24
0.51
5.6
4.3
2.19
1.89
mu/l
1.18
106
1009
52
457
1.21
0.47
1.7
1.9
96.35
92.89
pmol/l
0.14
24
228
6
94
0.62
0.43
1.8
1.9
—
—
—
0
0
5
32
1.58
0.42
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
170.13
—
0
17
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.49
0.40
1.0
1.1
—
—
—
0
0
16
202
0.77
0.39
1.3
1.3
110.43
27.48
iu/ml
—
7
69
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
39
348
1.16
0.30
3.6
3.8
4.77
8.24
mg/mmol
0.64
23
223
5
74
0.67
0.26
1.8
1.8
—
—
—
0
0
114
1178
0.88
0.25
4.7
4.2
4.42
4.59
mmol/l
1.06
102
1097
18
152
1.21
0.25
5.0
4.4
29.58
31.30
%
0.26
12
102
113
1168
0.88
0.25
4.7
4.2
1.39
1.43
mmol/l
0.48
100
1079
103
1070
0.89
0.24
6.1
5.6
39.64
39.93
mmol/mol
0.10
91
1006
108
1116
0.90
0.22
4.4
3.9
1.25
1.29
mmol/l
0.29
94
1028
17
145
1.19
0.21
1.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
36
330
1.12
0.19
4.0
3.6
22.85
23.79
%
0.14
20
157
117
1197
0.91
0.16
4.9
4.7
2.66
2.74
mmol/l
0.45
104
1109
29
270
1.09
0.11
1.3
1.6
—
—
—
0
0
5
46
1.09
0.09
1.6
1.6
0.16
0.22
g/l
—
5
46
5
46
1.09
0.09
1.2
1.7
—
—
—
0
0
19
204
0.92
0.07
1.5
1.8
1329.17
1117.30
nmol/l
0.41
12
161
117
1156
1.05
0.05
4.6
4.2
5.81
5.90
mmol/l
0.30
106
1044
10
104
0.96
0.00
1.8
1.8
—
—
—
0
0
84
845
0.99
0.00
4.2
3.3
—
—
—
0
0
24
242
0.99
0.00
2.2
2.7
0.97
0.79
ug/l
0.37
18
155
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.34
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
73.83
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
395.33
—
0
6
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_BONE_CARTILAGE_LIMBS – Malignant neoplasm of bone and articular cartilage of limbs
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).