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Chondrosarcoma, excluding all cancers (controls excluding all cancers)

Endpoint Browser PheWeb

C3_CHONDROSARCOMA_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C40.2|C4104|C4106|C4114|C4122|C4132|C4142|C4182|C4192
  • Cause of death: ICD-10 — C40.2|C4104|C4106|C4114|C4122|C4132|C4142|C4182|C4192
  • Cancer registry: Topography ICD-O-3 — ANY
  • Cancer registry: Morphology ICD-O-3 — 9220|9230|9231
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

163

4. Check minimum number of events

None

163

5. Include endpoints

None

163

6. Filter based on genotype QC (FinnGen only)

163

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

↥

List of similar endpoints to Chondrosarcoma, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 163 78 85
Unadjusted period prevalence (%) 0.03 0.03 0.04
Median age at first event (years) 56.95 56.81 57.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
94
Matched controls
938
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
206.5
29.5
29
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
25.1
23
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
24.0
22
*
130
Kela drug reimbursment
Malignant tumour
+∞
16.1
15
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
16.1
15
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
15.0
14
*
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
15.0
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.4
14.5
47
127
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
13.9
13
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
11.7
11
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
123.2
10.7
11
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.4
10.6
61
278
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.6
10
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
61.6
9.9
11
*
XX3DW
NOMESCO Finland
Time consuming IT work
10.8
9.6
18
20
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
9.5
9
*
JN4BD
NOMESCO Finland
Extensive body CT
10.3
9.3
18
21
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.3
9.2
17
18
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
9.8
9.1
18
22
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
8.5
8
*
WZC30
NOMESCO Finland
Teaching
6.6
8.2
21
39
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
49.2
7.9
9
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
49.2
7.9
9
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
7.4
7
*
C32.3
ICD-10 Finland
Malignant neoplasm: Laryngeal cartilage
+∞
7.4
7
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
+∞
7.4
7
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
+∞
7.4
7
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
7.4
7
*
NF3AA
NOMESCO Finland
Femur X-ray examination
22.1
7.3
10
5
B01AB05
ATC
enoxaparin; parenteral
3.5
7.3
43
182
H02AB02
ATC
dexamethasone; systemic
43.3
6.9
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.7
6.7
19
40
A03FA01
ATC
metoclopramide; systemic, rectal
5.4
6.7
20
45
R4110
NOMESCO Finland
Physiotherapy
3.5
6.6
37
148
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
74.7
6.5
7
*
WX402
NOMESCO Finland
General anaesthesia
4.5
6.4
23
63
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
6.3
6
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
6.3
6
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
6.3
6
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
6.3
6
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
6.3
6
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
6.3
6
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
6.3
6
*
GD1AD
NOMESCO Finland
Thorax CT examination
11.1
6.2
11
11
WX302
NOMESCO Finland
Thoracal epidural anesthesy
11.1
6.2
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
36
10.40
25.40
1.2
1.2
—
—
—
0
0
83
354
3.74
15.56
3.0
2.1
—
—
—
0
0
88
398
3.63
14.93
2.6
1.6
—
—
—
0
0
32
94
3.99
9.93
1.3
1.1
—
—
—
0
0
40
141
3.43
9.48
8.2
11.7
0.8
1.5
mmol/l
0.77
32
112
89
502
2.70
8.91
6.0
8.9
1.1
1.3
inr
1.79
22
127
13
21
6.64
7.84
1.5
1.4
—
—
—
0
0
60
294
2.65
7.76
4.4
3.2
85.4
90.0
%
0.85
60
287
23
65
3.96
7.45
2.5
1.8
1.9
3.0
ug/l
1.99
16
48
89
544
2.40
6.99
7.0
6.6
1.2
1.2
mmol/l
1.11
79
482
104
707
2.30
6.05
10.6
6.2
4.5
4.3
e9/l
0.09
95
613
129
968
2.59
5.91
9.8
5.2
77.9
74.2
u/l
0.71
124
888
22
73
3.33
5.62
11.7
11.3
1.3
1.6
%
0.96
22
73
108
761
2.24
5.55
6.0
5.1
6.7
6.8
mmol/l
0.25
101
701
20
63
3.48
5.53
4.3
18.0
—
—
—
0
0
22
74
3.28
5.50
11.9
11.2
0.9
0.7
%
0.81
22
74
19
59
3.51
5.36
12.1
10.5
24.2
24.9
mmol/l
0.61
19
54
34
154
2.53
4.97
1.9
1.8
—
—
—
0
0
56
325
2.10
4.55
5.0
4.1
—
—
—
0
0
50
282
2.12
4.36
7.3
4.5
—
—
—
0
0
85
582
1.96
4.30
6.3
5.5
8.4
8.5
%
0.01
79
542
64
399
1.99
4.23
5.3
5.2
—
—
—
0
0
86
594
1.95
4.22
6.2
5.3
25.4
28.2
%
1.27
78
551
84
578
1.94
4.14
5.9
5.2
3.0
3.1
%
0.09
78
534
62
385
1.99
4.13
4.9
2.0
2.4
2.3
mmol/l
0.24
57
311
90
643
1.89
3.88
5.4
5.2
1.7
1.9
e9/l
0.78
76
569
76
515
1.89
3.85
4.5
3.8
34.7
36.0
g/l
1.08
69
477
81
561
1.88
3.83
6.1
5.2
0.7
0.7
%
0.26
75
518
91
655
1.88
3.80
5.4
5.4
0.2
0.2
e9/l
0.48
77
574
88
628
1.87
3.77
5.2
5.2
0.6
0.6
e9/l
0.16
76
545
84
592
1.86
3.73
5.9
5.1
58.8
57.3
%
0.48
77
551
17
62
2.94
3.72
12.7
7.4
24.4
24.8
mmol/l
0.30
17
62
88
632
1.85
3.66
5.3
5.2
0.0
0.0
e9/l
0.14
76
546
23
103
2.44
3.41
11.4
7.2
0.9
1.4
mmol/l
2.85
23
96
20
87
2.48
3.15
3.4
11.6
—
—
—
0
0
18
77
2.50
2.94
5.1
4.8
0.8
0.3
%
—
10
12
7
13
5.57
2.90
3.4
7.2
10.8
12.8
mg/l
—
7
13
47
301
1.79
2.69
1.4
1.4
—
—
—
0
0
19
88
2.31
2.63
1.6
2.2
0.2
0.2
g/l
0.92
19
77
20
95
2.26
2.62
13.3
9.5
—
—
—
0
0
72
525
1.67
2.57
11.1
7.8
0.0
0.0
e9/l
0.39
56
413
103
830
1.65
2.44
4.5
4.2
—
243.1
—
0
15
5
8
6.40
2.39
3.4
1.4
31.4
32.8
pg
—
5
8
17
79
2.29
2.34
5.3
4.7
0.2
0.0
%
—
10
14
32
191
1.84
2.28
2.5
2.0
—
—
—
0
0
18
87
2.20
2.27
5.2
4.4
1.8
0.7
%
—
10
19
16
76
2.23
2.10
5.6
4.7
0.0
6.7
%
—
9
13
5
10
5.12
2.08
1.4
1.3
—
—
—
0
0
6
15
4.11
2.06
4.0
5.1
66.8
56.6
%
—
6
15
112
958
1.54
1.76
4.4
4.0
14.7
11.5
mm/h
1.06
106
875
143
1299
1.82
1.74
20.7
12.6
26.2
23.9
mg/l
0.39
126
972
108
919
1.52
1.72
3.5
3.8
—
—
—
0
0
50
368
1.52
1.59
3.5
3.2
—
—
—
0
0
5
15
3.40
1.53
4.0
4.1
5.6
3.9
e9/l
—
5
15
5
15
3.40
1.53
2.0
1.3
—
—
—
0
0
110
1231
0.67
1.51
6.3
6.2
40.1
40.6
mmol/mol
0.16
98
1148
20
118
1.79
1.49
1.4
1.3
—
—
—
0
0
147
1361
1.82
1.46
24.7
15.5
139.3
139.7
mmol/l
0.96
142
1317
147
1362
1.81
1.44
24.6
15.5
3.9
4.0
mmol/l
1.67
141
1318
21
129
1.72
1.38
3.3
3.9
—
—
—
0
0
5
119
0.40
1.30
1.2
1.3
—
—
—
0
0
15
86
1.82
1.24
6.2
3.1
—
—
—
0
0
46
351
1.43
1.20
2.6
3.3
7.4
7.4
ph
0.03
12
45
124
1341
0.69
1.19
4.3
5.2
2.6
2.7
mmol/l
0.54
106
1244
16
95
1.76
1.19
5.3
2.1
3.3
3.9
e9/l
0.54
11
76
0
34
0.00
1.17
0.0
1.3
—
—
—
0
0
121
1313
0.70
1.16
4.1
4.7
4.5
4.6
mmol/l
0.52
105
1224
5
20
2.55
1.16
1.8
1.2
—
—
—
0
0
5
20
2.55
1.16
2.4
1.4
—
—
—
0
0
0
36
0.00
1.15
0.0
1.1
—
—
—
0
0
11
58
1.96
1.15
2.4
4.1
—
—
—
0
0
7
30
2.39
1.14
1.0
1.1
—
—
—
0
0
121
1306
0.71
1.03
4.1
4.6
1.5
1.5
mmol/l
0.02
104
1211
14
85
1.71
0.98
1.9
1.4
—
—
—
0
0
42
329
1.37
0.94
5.4
3.7
0.0
0.0
estimate
0.00
20
91
6
114
0.51
0.86
1.5
1.5
—
—
—
0
0
6
33
1.85
0.80
1.7
1.4
293.2
328.5
e6/l
—
6
26
6
33
1.85
0.80
1.7
1.2
294.8
3.4
e6/l
—
6
26
0
27
0.00
0.78
0.0
2.0
—
30.2
—
0
22
8
132
0.59
0.77
3.4
3.5
6.3
5.7
kpa
—
8
126
8
134
0.58
0.77
1.4
1.6
—
—
—
0
0
144
1369
1.44
0.75
21.3
11.7
—
—
—
0
0
38
463
0.77
0.71
2.9
3.1
6.9
7.7
mmol/l
0.58
29
386
35
431
0.76
0.70
3.1
3.3
2175.7
61.0
mg/l
0.47
22
282
22
163
1.40
0.69
1.6
1.6
—
—
—
0
0
12
177
0.65
0.68
1.2
1.2
—
—
—
0
0
119
1265
0.78
0.67
3.7
4.2
1.2
1.3
mmol/l
2.28
104
1169
6
102
0.57
0.64
2.3
1.6
—
—
—
0
0
38
457
0.78
0.63
3.8
4.0
2.7
8.6
mg/mmol
2.60
22
294
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
151
1458
1.48
0.60
30.6
18.3
250.8
245.3
e9/l
0.49
145
1418
8
53
1.54
0.59
3.5
6.1
—
—
—
0
0
0
23
0.00
0.59
0.0
2.0
—
4.1
—
0
23
0
23
0.00
0.59
0.0
2.0
—
105.5
—
0
23
0
23
0.00
0.59
0.0
2.0
—
—
—
0
0
151
1459
1.47
0.58
30.6
18.3
4.4
4.5
e12/l
2.86
144
1416
151
1459
1.47
0.58
30.6
18.3
7.1
6.7
e9/l
0.33
144
1416
96
880
1.22
0.58
4.4
4.1
—
—
—
0
0
6
38
1.60
0.55
1.5
1.1
—
—
—
0
0
20
255
0.75
0.52
1.3
1.3
1.9
2.5
g/l
1.74
14
143
15
110
1.40
0.51
3.7
3.2
—
—
—
0
0
7
109
0.63
0.50
3.7
2.6
4.0
4.6
kpa
—
7
103
16
119
1.38
0.50
2.5
1.7
300.3
381.1
nmol/l
1.30
16
107
126
1200
1.22
0.45
4.8
4.5
1.9
1.9
mu/l
0.01
111
1090
40
461
0.82
0.45
2.8
3.0
—
—
—
0
0
145
1403
1.30
0.44
13.7
8.7
24.9
25.3
u/l
0.11
136
1343
5
31
1.63
0.43
1.4
1.4
—
285.5
ug/g
—
0
15
10
138
0.71
0.42
3.3
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
59
532
1.17
0.39
4.1
3.7
21.3
41.5
ng/l
1.69
49
372
16
201
0.77
0.38
1.3
1.3
2.9
10.5
u/ml
—
6
76
14
108
1.32
0.36
1.9
4.5
266.2
209.9
ng/l
0.13
14
98
6
42
1.44
0.36
1.5
1.6
—
—
—
0
0
6
44
1.38
0.35
3.0
1.8
—
—
—
0
0
44
392
1.17
0.34
4.4
3.9
—
—
—
0
0
124
1285
0.85
0.33
4.3
4.6
6.0
6.0
mmol/l
0.10
105
1170
13
163
0.78
0.31
1.2
1.4
—
384.0
—
0
45
67
621
1.13
0.30
5.4
5.0
0.0
0.0
estimate
0.00
19
90
11
85
1.32
0.29
1.2
1.4
—
—
—
0
0
35
311
1.16
0.28
1.9
2.0
3.1
3.1
mg/l
0.01
30
258
33
292
1.16
0.28
2.8
3.9
41.4
205.6
ng/l
1.44
28
231
14
113
1.26
0.27
1.4
1.4
—
—
—
0
0
19
224
0.83
0.27
1.1
1.3
20.1
32.9
iu/ml
—
8
66
121
1168
1.14
0.26
20.4
13.5
37.8
40.5
%
3.26
82
837
6
84
0.70
0.24
2.8
2.5
—
—
—
0
0
8
102
0.77
0.22
1.3
1.2
—
—
—
0
0
102
981
1.11
0.22
4.5
3.7
14.4
14.8
pmol/l
0.96
91
887
0
11
0.00
0.21
0.0
1.0
—
2.6
—
0
5
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
9.4
—
750.0
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
10.4
—
1248.7
—
0
10
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
25
278
0.88
0.18
2.2
1.7
380.3
438.7
pmol/l
0.75
17
232
34
314
1.10
0.16
2.9
2.7
—
—
—
0
0
31
285
1.11
0.15
4.0
3.5
—
—
—
0
0
65
620
1.08
0.15
4.7
3.6
0.0
0.0
estimate
0.00
19
92
51
483
1.08
0.14
4.0
3.7
3.2
2.0
ug/l
0.97
45
432
66
633
1.07
0.13
4.5
3.6
0.0
0.0
estimate
0.00
18
87
15
133
1.14
0.12
1.5
1.5
—
—
—
0
0
35
328
1.09
0.12
3.2
2.8
0.3
0.4
e6/l
0.11
27
234
48
502
0.94
0.10
4.1
3.4
—
—
—
0
0
5
48
1.04
0.09
1.6
2.2
88.6
368.7
ug/l
—
5
43
25
267
0.92
0.09
2.4
2.4
1.0
0.8
ug/l
0.64
19
167
37
352
1.07
0.09
4.5
3.3
—
—
—
0
0
20
215
0.92
0.08
1.6
1.7
—
—
—
0
0
7
66
1.06
0.08
2.7
2.1
—
—
—
0
0
8
78
1.03
0.07
1.6
1.8
10.0
10.8
g/l
—
8
71
32
307
1.05
0.05
4.1
3.9
1.0
1.0
kg/l
—
6
41
38
367
1.05
0.05
3.3
2.9
44.6
216.8
e6/l
0.48
29
281
57
561
1.02
0.02
1.8
2.0
97.6
93.3
pmol/l
0.21
33
274
27
278
0.97
0.02
1.1
1.3
1.3
1.3
u/ml
0.01
12
70
15
157
0.95
0.01
1.3
1.5
—
—
—
0
0
44
433
1.02
0.01
3.8
3.5
210.1
86.1
e6/l
0.30
31
302
27
264
1.03
0.00
1.6
1.7
1364.8
1168.8
nmol/l
0.43
19
192
10
96
1.04
0.00
1.3
1.4
—
—
—
0
0
26
264
0.98
0.00
5.5
4.7
—
—
—
0
0
6
65
0.92
0.00
1.7
1.4
1.2
1.2
g/l
—
6
60
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
25.1
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
1.3
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
144.2
—
0
6
0
9
0.00
0.00
0.0
1.9
—
13.0
—
0
9

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_CHONDROSARCOMA_EXALLC – Chondrosarcoma, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).