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This is a non-core endpoint: only basic statistics are computed.

Melanocytic naevi of ear and external auricular canal

Endpoint Browser

CD2_BENIGN_MELANOCYTIC_EAR_EXALLC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D22.2&
  • Hospital discharge: ICD-9 — 2162A
  • Cause of death: ICD-10 — D22.2&
  • Cause of death: ICD-9 — 2162A

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) auriculae

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 196 128 68
Unadjusted period prevalence (%) 0.04 0.04 0.03
Median age at first event (years) 52.02 46.05 63.26

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
184
Matched controls
1840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
+∞
244.7
176
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
29.5
45.4
62
31
DAB00
NOMESCO Finland
Excision of lesion of auricle
150.4
25.3
26
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.7
23.9
46
51
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
15.9
15
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
9.5
15.4
32
40
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
162.4
14.7
15
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
13.7
13
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
13.7
13
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
11.8
12.7
23
22
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
12.6
12
*
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
40.5
12.4
15
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
11.6
11
*
115
Kela drug reimbursment
Breast cancer
+∞
11.6
11
*
130
Kela drug reimbursment
Malignant tumour
+∞
10.5
10
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
20.2
10.4
15
8
R23.8
ICD-10 Finland
Other and unspecified skin changes
4.2
10.3
41
117
S82
ICPC
Naevus/mole
4.1
9.9
41
121
XQ845
NOMESCO Finland
Dermatoscopy
105.2
9.5
10
*
L57.0
ICD-10 Finland
Actinic keratosis
6.0
9.2
25
47
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
11.6
9.0
16
15
DAB10
NOMESCO Finland
Partial excision of auricle
+∞
8.4
8
*
2162A
ICD-9 Finland
Benign neoplasm of skin, Ear and external auditory canal[KORVAN IHON BEN KASVAIN,NAEVUS PIGMENTOSUS]
+∞
8.4
8
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
8.4
8
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.1
8.3
22
40
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
11.5
7.9
14
13
TQW99
NOMESCO Finland
Other minor procedure on skin
6.8
7.5
18
29
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
16.6
7.3
11
7
XQ848
NOMESCO Finland
Dermatological photography
10.7
7.2
13
13
H02AB02
ATC
dexamethasone; systemic
14.5
7.0
11
8
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5.9
6.8
18
33
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
18.8
6.3
9
5
A04AA02
ATC
granisetron; systemic, transdermal
+∞
6.3
6
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.9
6.1
24
68

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
119
528
4.19
21.76
3.0
1.6
—
—
—
0
0
28
37
8.66
20.51
1.5
1.1
—
—
—
0
0
48
123
4.84
18.09
1.8
1.1
—
—
—
0
0
23
57
4.44
8.80
3.4
1.7
3.1
7.6
ug/l
0.40
16
43
20
56
3.86
6.50
1.6
1.2
—
—
—
0
0
34
145
2.63
5.54
2.8
2.4
22.3
24.9
%
0.61
29
127
84
536
1.99
5.15
4.4
3.3
35.7
36.2
g/l
0.30
74
497
87
575
1.92
4.72
4.2
4.7
1.2
1.2
mmol/l
0.40
80
516
100
698
1.88
4.54
6.2
3.1
11.3
11.0
umol/l
0.13
94
646
141
1124
1.91
3.98
8.0
4.6
78.2
73.1
u/l
0.79
134
1036
24
102
2.54
3.92
3.5
2.8
178.8
214.1
ng/l
0.21
24
94
62
386
1.89
3.90
2.8
2.9
7.4
7.4
ph
—
7
62
110
823
1.77
3.72
9.2
6.3
4.4
4.2
e9/l
0.27
94
699
52
313
1.90
3.60
3.4
3.4
—
—
—
0
0
56
348
1.85
3.50
7.6
4.7
—
—
—
0
0
83
586
1.72
3.35
2.3
1.8
101.4
95.6
pmol/l
0.48
43
291
58
370
1.81
3.32
2.4
2.5
—
—
—
0
0
29
149
2.11
3.10
1.5
1.9
7.9
6.1
umol/l
0.29
22
122
5
5
10.21
2.99
6.8
2.6
5.6
6.1
nmol/l
—
5
5
8
18
4.59
2.82
1.3
1.0
—
—
—
0
0
45
283
1.77
2.66
3.8
3.2
90.2
157.9
ng/l
0.48
31
194
71
506
1.63
2.65
3.0
3.2
32.0
94.1
e6/l
1.44
54
333
57
384
1.68
2.64
2.5
2.5
0.2
0.4
e6/l
0.69
45
276
6
12
5.12
2.42
2.3
1.7
—
—
—
0
0
16
71
2.36
2.41
2.8
4.8
—
—
—
0
0
98
767
1.56
2.40
7.5
5.3
0.2
0.2
e9/l
0.18
89
667
25
134
1.99
2.40
5.1
7.5
1.8
1.3
mmol/l
0.24
16
103
8
23
3.58
2.29
1.3
1.2
—
—
—
0
0
59
415
1.60
2.27
2.7
2.6
72.4
278.9
e6/l
0.63
47
306
96
763
1.51
2.11
5.7
4.9
2.1
1.9
e9/l
0.82
86
667
6
15
4.09
2.05
1.0
1.1
—
—
—
0
0
64
469
1.54
2.05
5.4
4.8
—
—
—
0
0
175
1598
1.89
2.04
13.4
10.3
22.7
21.6
mg/l
0.14
140
1197
30
181
1.78
2.03
1.7
1.8
—
—
—
0
0
93
741
1.49
1.99
5.7
5.0
0.6
0.6
e9/l
0.51
82
631
6
16
3.83
1.95
2.2
1.3
—
—
—
0
0
20
107
1.97
1.94
2.4
3.2
—
—
—
0
0
88
698
1.47
1.90
5.7
5.0
56.5
56.9
%
0.12
82
647
93
746
1.47
1.90
5.7
5.0
0.0
0.0
e9/l
0.08
82
634
66
495
1.50
1.88
8.6
7.9
1.1
1.2
inr
1.65
11
147
12
53
2.35
1.84
7.8
10.6
—
—
—
0
0
9
35
2.65
1.82
5.4
3.0
—
—
—
0
0
14
67
2.17
1.81
1.0
1.1
—
—
—
0
0
84
666
1.46
1.80
6.1
5.0
0.7
0.7
%
0.08
76
609
88
704
1.45
1.80
6.0
5.1
29.1
28.9
%
0.04
82
650
10
41
2.52
1.78
1.7
1.8
—
—
—
0
0
60
450
1.48
1.69
3.5
1.7
2.3
2.4
mmol/l
0.26
47
380
8
31
2.65
1.68
1.0
1.1
—
—
—
0
0
8
31
2.65
1.68
1.0
1.1
—
—
—
0
0
55
406
1.49
1.67
2.1
1.9
—
—
—
0
0
47
336
1.52
1.66
1.6
1.4
21.0
21.7
nmol/l
0.12
42
291
85
688
1.42
1.58
6.3
5.2
8.6
8.3
%
0.39
79
638
85
689
1.41
1.56
6.1
5.0
3.0
2.9
%
0.21
79
634
9
37
2.50
1.50
1.2
1.2
—
—
—
0
0
46
602
0.69
1.37
2.3
2.7
—
—
—
0
0
5
17
2.99
1.36
1.0
1.1
—
—
—
0
0
5
17
2.99
1.36
1.4
1.0
—
—
—
0
0
123
1078
1.38
1.35
4.1
3.7
—
—
—
0
0
48
361
1.44
1.31
2.7
1.9
2.5
2.9
mg/l
0.49
40
308
18
109
1.72
1.24
3.8
2.8
—
—
—
0
0
5
19
2.67
1.22
1.2
1.3
—
—
—
0
0
97
829
1.34
1.21
4.4
3.9
6.6
6.6
mmol/l
0.01
87
744
13
72
1.86
1.18
3.2
2.2
23959.7
7381.3
u/l
—
7
25
49
383
1.37
1.07
5.6
3.9
1.8
2.1
ug/l
0.53
42
338
28
197
1.49
1.07
1.2
1.2
—
—
—
0
0
7
34
2.10
1.04
1.0
1.1
329.7
360.4
ug/g
—
7
17
54
432
1.35
1.02
3.2
3.1
2498.5
391.8
mg/l
0.63
32
270
179
1703
1.59
1.02
10.8
7.7
23.2
24.2
u/l
0.48
171
1635
17
108
1.63
1.00
1.6
1.4
—
—
—
0
0
33
244
1.42
0.99
2.8
1.9
2.4
2.4
mmol/l
0.05
28
205
158
1475
1.37
0.94
18.3
11.7
40.3
40.3
%
0.01
115
1105
55
448
1.32
0.92
3.3
4.0
4.3
11.1
mg/mmol
1.41
32
274
137
1260
1.29
0.87
3.6
3.8
14.5
14.6
pmol/l
0.24
125
1153
87
759
1.26
0.85
4.5
4.6
0.0
0.0
estimate
—
10
150
23
164
1.46
0.84
1.8
1.7
—
—
—
0
0
10
58
1.76
0.81
1.8
1.7
—
—
—
0
0
87
763
1.25
0.80
3.1
3.2
0.0
0.0
estimate
0.00
12
151
45
364
1.31
0.79
1.2
1.3
0.7
1.9
u/ml
—
6
108
5
24
2.11
0.75
2.6
2.8
3.6
5.3
umol/l
—
5
16
5
24
2.11
0.75
1.2
1.1
—
—
—
0
0
22
161
1.41
0.72
1.5
1.3
—
—
—
0
0
57
482
1.26
0.71
2.9
2.9
7.7
7.6
mmol/l
0.02
45
401
25
188
1.38
0.71
2.1
1.5
—
—
—
0
0
7
41
1.73
0.70
1.1
1.0
—
—
—
0
0
10
61
1.67
0.70
1.3
1.4
—
—
—
0
0
87
773
1.23
0.69
3.1
3.3
0.0
0.0
estimate
0.50
11
144
15
103
1.49
0.67
1.1
1.2
—
—
—
0
0
10
62
1.65
0.66
1.3
1.4
—
—
—
0
0
175
1682
1.38
0.66
16.2
11.5
76.4
74.9
umol/l
0.18
175
1682
14
95
1.51
0.66
1.3
1.2
197.4
140.4
u/ml
0.25
14
84
10
63
1.62
0.63
1.3
1.5
—
—
—
0
0
35
283
1.29
0.62
1.9
1.6
—
—
—
0
0
33
265
1.29
0.62
1.6
1.8
1135.5
1161.9
nmol/l
0.06
24
206
114
1049
1.21
0.61
3.7
3.5
—
—
—
0
0
175
1686
1.35
0.61
12.8
9.9
—
—
—
0
0
52
446
1.23
0.57
2.2
2.1
59.2
58.1
u/l
0.06
46
410
9
63
1.45
0.53
1.2
1.5
257.4
275.1
mu/l
—
9
58
48
413
1.21
0.51
1.5
1.6
—
—
—
0
0
25
200
1.29
0.49
3.3
2.3
78.8
103.5
ug/g
0.41
20
162
39
330
1.23
0.49
3.3
3.2
—
—
—
0
0
14
102
1.40
0.49
6.6
8.5
—
—
—
0
0
40
340
1.22
0.48
4.4
4.1
—
—
—
0
0
15
111
1.38
0.48
6.4
6.7
1.5
1.4
mmol/l
0.19
15
104
7
50
1.41
0.45
1.3
1.9
1.1
1.5
g/l
—
7
44
38
324
1.21
0.45
4.4
1.7
1.8
0.9
mg/l
0.43
30
252
7
51
1.39
0.44
3.3
3.4
—
—
—
0
0
5
33
1.53
0.41
1.4
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
13
97
1.36
0.40
2.4
1.7
10.3
10.4
g/l
0.08
13
90
66
597
1.16
0.40
3.0
3.0
—
—
—
0
0
76
696
1.15
0.39
8.0
7.4
0.0
0.0
e9/l
0.00
61
551
12
89
1.37
0.39
1.2
1.2
—
—
—
0
0
183
1792
1.32
0.37
22.2
15.6
258.2
255.0
e9/l
0.30
178
1749
51
455
1.16
0.37
2.5
2.9
—
—
—
0
0
146
1403
1.16
0.36
21.0
13.8
331.0
332.5
g/l
1.40
146
1394
25
209
1.22
0.36
3.0
2.6
0.7
0.8
ug/l
0.45
16
139
183
1794
1.30
0.35
22.2
15.6
4.6
4.5
e12/l
0.57
178
1745
183
1795
1.29
0.33
22.2
15.6
7.0
6.6
e9/l
1.99
178
1746
10
131
0.75
0.32
4.0
2.9
—
—
—
0
0
7
53
1.33
0.31
1.3
1.1
—
—
—
0
0
7
53
1.33
0.31
1.4
1.2
—
—
—
0
0
14
111
1.28
0.31
1.4
1.3
—
45.9
—
0
7
16
195
0.80
0.30
1.3
1.4
—
—
—
0
0
156
1515
1.15
0.28
4.6
4.5
2.2
2.6
mu/l
0.20
142
1388
163
1588
1.16
0.28
4.2
4.2
4.7
4.7
mmol/l
0.24
151
1483
8
66
1.22
0.27
1.3
1.3
—
—
—
0
0
9
72
1.26
0.26
3.4
1.9
14.8
13.7
nmol/l
—
9
66
40
441
0.88
0.25
1.5
1.6
1.3
1.3
mmol/l
0.55
35
380
150
1458
1.12
0.25
5.7
5.3
38.5
39.3
mmol/mol
0.67
140
1365
49
450
1.12
0.24
3.2
2.6
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
12.9
9.7
u/l
—
5
31
5
39
1.29
0.23
1.2
1.2
79.8
49.3
pmol/l
—
5
39
10
79
1.28
0.22
2.1
1.2
—
—
—
0
0
157
1533
1.12
0.22
4.7
4.1
5.9
5.8
mmol/l
0.56
143
1403
5
41
1.23
0.22
2.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
32
289
1.13
0.20
1.4
1.8
384.6
22891999.4
pmol/l
0.50
26
249
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
52
1.16
0.19
1.3
1.5
—
—
—
0
0
23
204
1.14
0.19
1.9
1.9
—
—
—
0
0
11
132
0.82
0.19
1.6
1.3
—
—
—
0
0
121
1173
1.08
0.18
3.9
3.7
11.7
10.2
mm/h
0.46
110
1079
8
72
1.12
0.16
1.3
1.4
—
—
—
0
0
6
78
0.76
0.16
1.2
1.2
20.2
22.4
iu/l
—
6
68
8
96
0.83
0.14
1.6
2.1
—
—
—
0
0
12
138
0.86
0.13
1.2
1.2
120.4
143.2
iu/ml
—
5
63
164
1616
1.09
0.13
4.9
4.6
2.7
2.8
mmol/l
0.23
152
1505
9
105
0.85
0.13
1.9
3.1
4.6
4.7
pmol/l
—
9
96
52
546
0.94
0.12
2.8
3.6
20.4
32.5
ng/l
0.89
31
342
13
115
1.14
0.11
1.2
1.4
—
—
—
0
0
160
1579
1.07
0.10
4.3
4.1
1.5
1.5
mmol/l
0.07
147
1467
5
46
1.09
0.09
4.4
1.8
163.9
374.6
ug/l
—
5
41
41
390
1.06
0.09
2.6
3.5
—
—
—
0
0
5
47
1.07
0.09
4.4
3.5
—
—
—
0
0
6
57
1.05
0.08
1.3
1.7
—
—
—
0
0
5
62
0.80
0.08
2.4
2.3
1.2
1.2
%
—
5
62
39
408
0.94
0.08
3.6
3.4
0.0
0.0
estimate
0.00
12
148
19
176
1.09
0.08
1.2
1.5
—
—
—
0
0
6
71
0.84
0.08
2.2
2.4
—
—
—
0
0
15
137
1.10
0.07
1.2
1.1
—
—
—
0
0
8
77
1.04
0.07
1.3
1.4
—
—
—
0
0
8
77
1.04
0.07
1.3
1.3
—
—
—
0
0
8
77
1.04
0.07
1.3
1.4
—
—
—
0
0
8
78
1.03
0.07
1.3
1.3
—
—
—
0
0
10
89
1.13
0.07
7.4
5.8
0.0
0.1
%
—
5
20
30
286
1.06
0.06
1.2
1.2
0.9
11.1
u/ml
2.00
12
110
34
326
1.05
0.06
1.5
1.3
2.3
2.4
g/l
0.13
18
183
12
131
0.91
0.06
2.2
3.6
—
—
—
0
0
153
1517
1.04
0.04
3.9
3.7
1.3
1.2
mmol/l
0.63
139
1390
31
300
1.04
0.03
1.3
1.3
16.9
41.1
iu/ml
—
9
93
10
93
1.08
0.02
7.4
5.6
0.2
0.7
%
—
5
22
13
124
1.05
0.00
2.2
3.6
3.4
2.1
mmol/l
—
7
88
36
358
1.01
0.00
2.5
1.9
—
—
—
0
0
21
208
1.01
0.00
1.7
1.8
—
—
—
0
0
10
102
0.98
0.00
1.8
1.8
—
—
—
0
0
11
115
0.95
0.00
1.1
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
10.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
16
160
1.00
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
6
65
0.92
0.00
2.2
3.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
24.5
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
19.7
—
0
5
0
6
0.00
0.00
0.0
1.3
—
84.6
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
2.4
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_MELANOCYTIC_EAR_EXALLC – Melanocytic naevi of ear and external auricular canal

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).