No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF8
- Parent code in ICD-10
- C81-C96
- Name in latin
- Leuc(h)aemiae typo cellulari non specificato
Similar endpoints
↥List of similar endpoints to
Leukaemia of unspecified cell type
based on the number of shared cases.
Similar with more cases:
- Leukaemia of unspecified cell type
- Primary_lymphoid and hematopoietic malignant neoplasms
- Primary_lymphoid and hematopoietic malignant neoplasms
- Malignant neoplasm
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 303 | 132 | 171 |
| Unadjusted period prevalence (%) | 0.06 | 0.04 | 0.08 |
| Median age at first event (years) | 62.58 | 56.99 | 66.89 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 298
- Matched controls
- 2978
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
360.4
212.3
193
15
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
211.5
177
*
XW000
NOMESCO Finland
Bone marrow biopsy
122.0
150.6
155
26
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
133.7
118
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
93.8
85
*
WW500
NOMESCO Finland
Blood transfusion
57.7
84.0
98
25
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
69.9
79.0
89
18
L03AA02
ATC
filgrastim; parenteral
+∞
68.4
63
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
65.0
60
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
59.4
55
*
A04AA01
ATC
ondansetron; systemic, rectal
40.5
59.1
74
24
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
565.5
49.9
48
*
A05AA02
ATC
ursodeoxycholic acid; oral
107.0
49.7
53
6
H02AB02
ATC
dexamethasone; systemic
67.0
48.5
55
10
127
Kela drug reimbursment
Transplant complication
72.8
48.2
54
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.1
47.9
114
189
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
15.0
45.4
79
70
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
44.9
42
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
16.6
43.5
72
56
J05AB11
ATC
valaciclovir; oral
8.5
41.2
100
166
ZX120
NOMESCO Finland
Intravenous
11.0
39.8
81
98
L01BB02
ATC
mercaptopurine; oral
83.2
39.1
43
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
67.5
36.2
41
7
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
35.1
33
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
+∞
35.1
33
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
35.1
33
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
377.8
34.7
34
*
JN4BD
NOMESCO Finland
Extensive body CT
13.0
33.9
62
59
M04AA01
ATC
allopurinol; systemic
6.6
32.8
96
201
R50.9
ICD-10 Finland
Fever, unspecified
6.7
32.6
93
188
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
30.0
179
786
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
29.7
28
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.5
29.4
101
254
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
+∞
28.6
27
*
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
28.6
27
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.9
27.6
75
139
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
27.5
26
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
12.5
26.2
48
45
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
14.5
25.8
44
35
L04AD01
ATC
ciclosporin; systemic
22.4
23.6
34
17
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
10.5
23.1
46
51
ZX090
NOMESCO Finland
Other technic of radiotherapy
129.9
22.9
24
*
WW200
NOMESCO Finland
Immunization
14.9
22.1
37
28
J01MA12
ATC
levofloxacin; systemic
4.4
21.5
90
267
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
23.7
21.3
30
14
L03AA13
ATC
pegfilgrastim; parenteral
+∞
21.1
20
*
L01XX05
ATC
hydroxycarbamide; oral
25.6
20.4
28
12
189
Kela drug reimbursment
Imatinib
+∞
20.0
19
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
21.2
19.9
29
15
ZXD05
NOMESCO Finland
Urgent procedure
3.3
19.8
133
578
J02AC03
ATC
voriconazole; systemic
213.5
19.8
20
*
TAB00
NOMESCO Finland
Lumbar puncture
9.2
19.8
42
52
D64.9
ICD-10 Finland
Anaemia, unspecified
5.4
19.7
63
140
L01XE01
ATC
[U] imatinib; oral
+∞
18.9
18
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
18.9
18
*
Z51.5
ICD-10 Finland
Palliative care
16.5
18.9
30
20
A41.9
ICD-10 Finland
Sepsis, unspecified
10.9
18.2
35
36
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
28.8
18.1
24
9
N02AA05
ATC
oxycodone; systemic
5.2
18.1
60
138
A03FA01
ATC
metoclopramide; systemic, rectal
4.5
17.8
68
182
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
53.3
17.2
20
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
16.4
17.0
27
18
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.9
16.8
36
45
B73
ICPC
Leukaemia
+∞
16.8
16
*
115
Kela drug reimbursment
Breast cancer
+∞
16.8
16
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
50.5
16.2
19
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
15.9
111
482
H02AB09
ATC
hydrocortisone; systemic
11.0
15.8
30
30
ZX121
NOMESCO Finland
Central venous catheter
+∞
15.8
15
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
15.8
15
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
15.8
15
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
168.4
15.6
16
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
14.7
14
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
14.7
14
*
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
14.7
14
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
14.7
14
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
157.3
14.6
15
*
ZXE00
NOMESCO Finland
One hour or less
2.6
13.7
135
710
ZX112
NOMESCO Finland
Subcutaneous
35.9
13.6
17
5
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
13.6
13
*
J02AC04
ATC
posaconazole; systemic
+∞
13.6
13
*
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
13.6
13
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
13.6
13
*
TPH00
NOMESCO Finland
Phlebotomy
146.3
13.6
14
*
2AX04
NOMESCO Finland
NA
+∞
12.6
12
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
12.6
12
*
J05AB01
ATC
aciclovir; systemic
3.1
12.5
80
319
L04AA06
ATC
mycophenolic acid; systemic
14.2
12.1
20
15
J01MA14
ATC
moxifloxacin; systemic
4.4
11.9
44
112
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
67.6
11.7
13
*
JN4AD
NOMESCO Finland
Body CT examination
7.5
11.6
27
39
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
11.5
11
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
11.5
11
*
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
+∞
11.5
11
*
130
Kela drug reimbursment
Malignant tumour
+∞
11.5
11
*
9801/3-C42.1
ICD-O-3
Acute leukemia, NOS, of bone marrow
+∞
11.5
11
*
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
+∞
11.5
11
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
124.5
11.5
12
*
ZX131
NOMESCO Finland
Intrathecal
124.5
11.5
12
*
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
36.6
11.4
14
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
17.9
11.3
17
10
D70.82
ICD-10 Finland
Drug-induced neutropenia
26.2
11.2
15
6
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
45.1
11.0
13
*
ZX108
NOMESCO Finland
Inhalation
45.1
11.0
13
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.6
10.8
93
440
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
10.8
36
83
5BA08
NOMESCO Finland
NA
62.2
10.7
12
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
113.8
10.5
11
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
113.8
10.5
11
*
152
Kela drug reimbursment
Nilotinib
+∞
10.5
10
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
10.5
10
*
1DB06
NOMESCO Finland
NA
+∞
10.5
10
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
10.5
10
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
10.5
10
*
2089X
ICD-9 Finland
Leukaemia of unspecified cell type, Unspecified leukaemia
+∞
10.5
10
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
24.4
10.3
14
6
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.4
10.3
22
28
A07AA02
ATC
nystatin; oral
5.3
10.2
31
64
L02BA01
ATC
tamoxifen; oral
41.5
10.0
12
*
Z2221
NOMESCO Finland
Medical doctor
2.5
9.4
88
432
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
9.4
9
*
116
Kela drug reimbursment
Prostate cancer
+∞
9.4
9
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
+∞
9.4
9
*
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
+∞
9.4
9
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
9.4
9
*
Z3231
NOMESCO Finland
Registered nurse
2.4
9.3
91
456
ZX114
NOMESCO Finland
Intramuscular
14.3
9.3
15
11
212
Kela drug reimbursment
Gout
10.5
9.1
17
17
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
9.1
82
393
Z2446
NOMESCO Finland
Social worker
4.0
9.1
36
98
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.5
9.1
23
38
H02AB04
ATC
methylprednisolone; systemic
3.0
9.1
56
215
N05BA06
ATC
lorazepam; systemic, sublingual
5.0
8.9
28
61
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
51.5
8.7
10
*
L02BG04
ATC
letrozole; oral
20.7
8.5
12
6
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
8.5
129
789
1XC02
NOMESCO Finland
NA
92.5
8.5
9
*
TPX15
NOMESCO Finland
Removal of vascular injection port
92.5
8.5
9
*
J02AC01
ATC
fluconazole; systemic
2.2
8.4
110
628
A41.8
ICD-10 Finland
Other specified sepsis
11.2
8.4
15
14
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
8.4
8
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
8.4
8
*
L01XE06
ATC
[U] dasatinib; systemic
+∞
8.4
8
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
8.4
8
*
316
Kela drug reimbursment
Imatinib
+∞
8.4
8
*
150
Kela drug reimbursment
Dasatinib
+∞
8.4
8
*
2AA01
NOMESCO Finland
NA
+∞
8.4
8
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.2
8.2
19
28
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.6
8.2
23
44
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.4
8.2
40
131
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
8.2
35
103
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
34.3
8.1
10
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.0
8.0
21
37
R4110
NOMESCO Finland
Physiotherapy
2.4
8.0
79
394
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
13.5
7.9
13
10
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
7.7
89
478
B01AB05
ATC
enoxaparin; parenteral
2.2
7.6
85
450
L04AA01
ATC
[U] ciclosporin; systemic
10.4
7.6
14
14
HAC20
NOMESCO Finland
Total mastectomy
82.0
7.4
8
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
82.0
7.4
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
7.4
30
84
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.5
7.4
25
59
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.3
7
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
7.3
7
*
WW409
NOMESCO Finland
Other aferesis
+∞
7.3
7
*
L01XE08
ATC
[U] nilotinib; oral
+∞
7.3
7
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
7.3
7
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
7.3
7
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
7.3
7
*
1XX02
NOMESCO Finland
NA
+∞
7.3
7
*
WA010
NOMESCO Finland
Adjuvant whole body radiotherapy
+∞
7.3
7
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.7
7.3
31
91
ZZR00
NOMESCO Finland
Flap of skin
30.8
7.2
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
7.1
105
624
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.6
7.0
31
94
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.5
6.9
23
54
J01MA02
ATC
ciprofloxacin; systemic
2.0
6.8
113
702
6BA02
NOMESCO Finland
NA
41.0
6.8
8
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
6.7
40
151
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
6.7
29
87
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
4.9
6.5
20
43
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
71.3
6.4
7
*
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
71.3
6.4
7
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.1
6.4
24
63
B02.9
ICD-10 Finland
Zoster without complication
3.9
6.4
25
69
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
11.4
6.3
11
10
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
6.3
6
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
6.3
6
*
1CX01
NOMESCO Finland
NA
+∞
6.3
6
*
Y77
ICPC
Malignant neoplasm prostate
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
L01EA03
ATC
nilotinib; oral
+∞
6.3
6
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
9800/3-C42.1
ICD-O-3
Leukemia, NOS, of bone marrow
+∞
6.3
6
*
5AD01
NOMESCO Finland
NA
+∞
6.3
6
*
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
6.3
6
*
A40.8
ICD-10 Finland
Other streptococcal sepsis
27.3
6.3
8
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.6
6.2
27
81
HA1AA
NOMESCO Finland
X-ray mammography
6.3
6.1
15
25
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: CD2_LEUKAEMIA_NAS_EXALLC – Leukaemia of unspecified cell type
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).