This is a non-core endpoint: only basic statistics are computed.
Benign neoplasm: Short bones of lower limb
CD2_BENIGN_BONE_SHORT_LOWER_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D16
- Name in latin
- Neoplasma benignum ossium brevium membri inferioris
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Short bones of lower limb
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Short bones of lower limb
- Benign neoplasm of bone and articular cartilage
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 368 | 223 | 145 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | 34.82 | 32.20 | 38.84 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 334
- Matched controls
- 3341
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.3
ICD-10 Finland
Benign neoplasm: Short bones of lower limb
+∞
221.3
187
*
21307
ICD-8 Finland
Benign neoplasm of bone and cartilage, Ossium brevium extremitatis inferioris
+∞
97.8
89
*
2138A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Short bones of lower limb
+∞
63.6
59
*
NHR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of ankle or foot
+∞
54.7
51
*
9102
FHL
Trepanation or removal of the local bone process
37.6
31.7
40
12
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
20.9
23.1
34
18
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
29.8
22.7
30
11
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
33.8
21.9
28
9
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
55.8
18.2
21
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
13.6
13
*
130
Kela drug reimbursment
Malignant tumour
+∞
13.6
13
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
13.6
13
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.2
12.9
50
133
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
10.5
10
*
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
15.6
9.6
15
10
H02AB02
ATC
dexamethasone; systemic
15.6
9.6
15
10
N02AX02
ATC
tramadol; systemic, rectal
2.1
9.5
140
843
ZXA05
NOMESCO Finland
Left side
2.4
9.0
87
430
9103
FHL
Partial or complete bone removal
46.1
7.7
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
7.7
100
559
R03AC02
ATC
salbutamol; inhalant
1.9
7.6
178
1251
NHR30
NOMESCO Finland
Complete excision of soft tissue tumour of ankle or foot
81.8
7.4
8
*
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
7.1
7.4
17
25
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
115
Kela drug reimbursment
Breast cancer
+∞
7.3
7
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
30.7
7.2
9
*
N02AA05
ATC
oxycodone; systemic
3.2
6.9
36
123
WX110
NOMESCO Finland
Local anesthesy
1.9
6.7
225
1757
WX320
NOMESCO Finland
Spinalanesthesy
2.1
6.7
78
417
9104
FHL
Autogenous bone graft
71.1
6.4
7
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
6.4
149
1023
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
6.3
6
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.5
6.2
51
228
X58
ICD-10 Finland
Exposure to other specified factors
2.4
6.0
50
226
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
180
1230
1.91
8.41
4.5
3.8
—
—
—
0
0
7
5
14.23
4.59
1.4
1.2
68.4
57.2
nmol/l
—
7
5
59
350
1.82
3.96
3.7
2.8
0.8
0.8
mmol/l
1.07
54
324
28
133
2.20
3.50
3.7
1.6
7.1
2.8
ug/l
0.55
21
104
85
593
1.56
3.09
2.1
2.0
—
—
—
0
0
254
2208
1.49
3.05
4.2
4.0
9.6
10.3
mm/h
0.49
240
2033
30
155
2.02
3.05
1.3
1.5
—
—
—
0
0
244
2115
1.46
2.89
7.7
5.3
78.2
73.7
u/l
0.65
234
1951
164
1325
1.43
2.85
6.6
3.9
11.5
11.1
umol/l
0.14
154
1238
11
36
3.12
2.83
1.5
1.2
—
—
—
0
0
6
10
6.08
2.71
1.5
1.1
8.0
17.1
u/l
—
6
10
48
300
1.69
2.70
2.7
2.2
23.5
24.8
%
0.23
41
262
13
49
2.71
2.65
1.3
1.2
—
—
—
0
0
13
49
2.71
2.65
1.3
1.2
—
—
—
0
0
134
1055
1.42
2.64
5.4
3.9
36.0
36.3
g/l
0.32
126
966
11
38
2.95
2.60
1.6
1.1
—
—
—
0
0
6
12
5.06
2.41
1.7
4.3
255.7
412.9
u/ml
—
6
12
117
917
1.40
2.32
3.5
2.9
—
—
—
0
0
320
2985
1.55
2.15
14.5
10.9
19.7
20.5
mg/l
0.19
256
2263
98
754
1.41
2.14
4.2
3.5
0.0
0.0
estimate
0.69
32
253
23
124
1.91
2.12
2.4
1.4
26.7
30.3
u/ml
0.11
23
119
186
1596
1.33
2.02
4.7
4.5
6.3
6.6
mmol/l
1.80
177
1465
107
845
1.38
2.00
3.4
1.9
2.4
2.3
mmol/l
0.31
93
708
111
883
1.37
1.98
3.2
2.3
95.9
56.0
u/l
0.45
101
810
5
11
4.59
1.94
1.2
1.4
—
—
—
0
0
258
2331
1.36
1.93
4.5
3.9
14.5
14.6
pmol/l
0.41
245
2127
12
52
2.35
1.89
1.1
1.4
—
—
—
0
0
15
72
2.13
1.89
1.4
2.5
7.3
10.8
mg/l
1.50
15
67
181
1561
1.31
1.84
7.9
6.6
4.1
4.1
e9/l
0.22
162
1362
21
120
1.80
1.66
1.4
2.4
34.5
40.0
u/l
0.66
21
108
36
239
1.56
1.65
3.8
2.8
—
—
—
0
0
166
1433
1.29
1.61
5.2
4.6
0.0
0.0
estimate
0.00
36
255
167
1451
1.28
1.52
4.0
3.3
0.0
0.0
estimate
0.00
35
250
74
575
1.36
1.51
1.3
1.3
12.0
32.8
iu/ml
4.11
21
180
60
452
1.39
1.48
3.2
2.4
0.8
0.7
ug/l
0.14
43
274
22
135
1.67
1.39
1.6
2.0
—
—
—
0
0
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
0
38
0.00
1.35
0.0
1.2
—
—
—
0
0
0
39
0.00
1.34
0.0
1.2
—
—
—
0
0
6
24
2.52
1.31
1.2
1.3
—
—
—
0
0
35
245
1.47
1.29
5.8
9.3
1.0
1.3
mmol/l
0.22
23
196
88
718
1.30
1.29
2.5
2.3
344.3
7440.0
umol/l
3.09
79
639
5
18
2.80
1.29
1.2
1.3
—
—
—
0
0
50
375
1.39
1.28
1.8
1.7
—
—
—
0
0
128
1096
1.26
1.27
6.3
5.4
1.2
1.2
mmol/l
0.01
114
976
296
2790
1.31
1.26
12.3
9.5
85.2
85.3
ml/min/173m2
0.02
253
2224
87
711
1.29
1.26
3.1
2.6
0.3
0.4
e6/l
0.35
64
525
162
1430
1.24
1.22
4.0
3.3
0.0
0.0
estimate
0.00
32
252
0
35
0.00
1.15
0.0
1.1
—
—
—
0
0
296
2800
1.29
1.15
5.2
4.6
1.7
2.3
mu/l
0.75
283
2580
131
1138
1.23
1.13
4.3
3.3
—
—
—
0
0
43
324
1.37
1.09
27.3
18.1
1.1
1.3
inr
—
9
45
78
641
1.28
1.08
4.4
3.3
20.4
23.7
%
1.33
39
271
10
52
1.95
1.07
1.6
1.2
127.2
121.0
u/ml
—
5
10
62
496
1.30
1.06
4.3
3.8
1204.5
180.7
ng/l
0.87
43
357
28
198
1.45
1.01
1.4
1.5
—
—
—
0
0
9
48
1.90
1.01
3.4
1.1
15.8
3.6
ug/l
—
9
43
79
657
1.26
1.00
1.9
1.6
—
—
—
0
0
35
259
1.39
0.99
1.7
1.6
—
—
—
0
0
5
23
2.19
0.98
3.4
5.0
—
—
—
0
0
7
36
1.96
0.97
1.3
1.4
—
—
—
0
0
9
50
1.82
0.97
1.2
1.3
—
—
—
0
0
35
261
1.38
0.96
1.6
1.7
—
—
—
0
0
6
27
2.24
0.94
1.2
1.3
—
—
—
0
0
10
55
1.84
0.93
1.6
1.2
—
—
—
0
0
66
544
1.26
0.90
1.2
1.3
1.5
10.3
u/ml
3.23
30
227
79
665
1.24
0.90
2.3
2.0
2.9
3.0
mg/l
0.02
72
565
25
178
1.43
0.89
1.0
1.0
—
—
—
0
0
288
2744
1.23
0.87
4.9
5.4
37.9
39.4
mmol/mol
2.32
269
2579
8
45
1.79
0.84
1.3
1.3
—
—
—
0
0
131
1167
1.19
0.84
2.3
2.3
77.6
75.0
nmol/l
0.51
123
1048
10
57
1.78
0.84
1.0
1.6
—
—
—
0
0
28
206
1.39
0.84
4.4
1.8
61.1
72.6
ml/min/173m2
0.96
15
75
137
1228
1.18
0.82
7.9
5.7
1.2
1.2
mmol/l
0.11
120
1046
85
729
1.22
0.82
1.2
1.3
0.5
2.2
u/ml
1.99
21
208
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
36
280
1.32
0.78
2.9
1.8
320.5
372.8
nmol/l
1.49
36
261
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
6
34
1.78
0.76
1.0
1.2
—
—
—
0
0
6
34
1.78
0.76
1.0
1.2
—
—
—
0
0
9
53
1.72
0.76
1.2
1.1
—
—
—
0
0
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
7
43
1.64
0.67
1.1
1.3
—
—
—
0
0
7
44
1.60
0.65
1.0
1.0
1.3
1.4
g/l
—
7
38
305
2948
1.20
0.64
4.4
4.1
5.7
5.9
mmol/l
2.86
292
2699
15
104
1.46
0.63
2.3
1.8
—
—
—
0
0
11
71
1.57
0.62
1.4
1.3
—
—
—
0
0
5
30
1.68
0.61
1.2
1.5
—
—
—
0
0
10
151
0.65
0.61
1.6
2.0
1.8
3.2
mg/l
—
5
103
0
22
0.00
0.59
0.0
1.0
—
606.6
—
0
16
0
22
0.00
0.59
0.0
1.0
—
43.3
—
0
14
6
35
1.73
0.58
1.0
1.2
—
—
—
0
0
6
35
1.73
0.58
1.0
1.2
—
—
—
0
0
6
35
1.73
0.58
1.0
1.2
—
—
—
0
0
8
54
1.49
0.57
1.3
1.2
—
—
—
0
0
5
86
0.58
0.57
1.4
1.3
329.0
407.8
mg/l
—
5
78
5
87
0.57
0.57
1.0
1.3
7.0
7.5
g/l
—
5
69
5
87
0.57
0.57
1.0
1.3
—
—
—
0
0
310
3010
1.19
0.56
4.1
4.2
1.5
1.5
mmol/l
0.06
293
2808
47
396
1.21
0.56
3.0
2.6
9.2
3.2
e6/l
0.93
23
205
311
3023
1.19
0.54
4.2
4.2
4.7
4.7
mmol/l
0.05
295
2828
9
61
1.49
0.54
1.1
1.1
—
—
—
0
0
19
143
1.35
0.53
1.5
1.4
—
—
—
0
0
12
83
1.46
0.52
1.5
1.8
3.9
7.1
iu/l
—
5
30
31
253
1.25
0.50
1.1
1.2
224.7
117.1
iu/ml
—
9
113
12
84
1.44
0.50
1.7
1.8
—
—
—
0
0
72
807
0.87
0.49
1.6
1.7
1.5
1.4
mmol/l
0.24
59
692
53
459
1.18
0.48
2.6
1.9
2.4
2.4
mmol/l
0.89
44
380
219
2088
1.12
0.48
3.4
2.9
45.2
41.8
u/l
0.32
207
1971
11
77
1.44
0.46
2.3
1.3
—
—
—
0
0
75
672
1.15
0.45
4.5
3.5
1.0
1.0
kg/l
0.09
13
92
298
2902
1.14
0.42
3.8
3.8
1.3
1.3
mmol/l
0.06
279
2694
30
250
1.22
0.42
2.5
2.0
27.1
30.9
u/l
0.64
25
210
5
33
1.52
0.41
1.0
1.3
—
—
—
0
0
15
114
1.33
0.41
1.5
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
1.1
—
0
6
8
61
1.32
0.40
1.7
1.2
—
—
—
0
0
17
133
1.29
0.39
6.5
9.4
0.7
0.7
%
0.10
17
133
11
81
1.37
0.36
1.5
1.1
—
—
—
0
0
6
41
1.47
0.36
1.0
1.0
—
—
—
0
0
5
76
0.65
0.36
1.2
1.2
3.3
3.7
mmol/l
—
5
69
5
78
0.64
0.36
1.6
1.2
2.2
1568.3
e6/l
—
5
62
23
190
1.22
0.35
1.3
1.3
—
—
—
0
0
6
43
1.40
0.35
2.0
2.3
13.1
13.3
%
—
6
43
48
427
1.14
0.33
2.8
2.4
1.8
0.9
e6/l
0.62
24
235
71
649
1.12
0.33
1.6
1.7
0.8
1.0
mg/l
0.36
51
474
17
138
1.24
0.31
2.4
2.3
420.9
4762.1
u/l
—
7
53
14
111
1.27
0.30
2.1
1.6
—
—
—
0
0
70
643
1.11
0.30
1.5
1.5
22.6
21.5
nmol/l
0.26
65
557
18
150
1.21
0.27
3.1
2.8
0.2
1.6
mmol/l
1.03
11
107
312
3069
1.11
0.27
4.5
4.6
2.8
2.8
mmol/l
0.21
296
2853
52
475
1.11
0.25
2.4
2.2
—
—
—
0
0
12
96
1.26
0.25
2.1
1.7
—
—
—
0
0
14
115
1.23
0.24
1.7
1.5
—
—
—
0
0
13
106
1.23
0.23
1.5
1.4
—
—
—
0
0
13
106
1.23
0.23
1.5
1.4
—
—
—
0
0
13
106
1.23
0.23
1.5
1.4
—
—
—
0
0
13
106
1.23
0.23
1.5
1.4
—
—
—
0
0
12
97
1.25
0.23
1.2
1.1
—
—
—
0
0
27
305
0.88
0.23
1.7
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
12
98
1.23
0.21
1.2
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
392.1
—
0
7
11
89
1.24
0.21
2.1
1.7
—
—
—
0
0
5
43
1.16
0.21
1.2
1.1
—
—
—
0
0
289
2848
1.07
0.18
13.7
11.7
40.6
40.5
%
0.04
226
2171
7
63
1.11
0.17
3.0
3.2
—
—
—
0
0
116
1117
1.06
0.16
1.9
1.9
98.8
96.3
pmol/l
0.20
59
561
60
566
1.07
0.16
1.5
1.7
413.1
13958755.3
pmol/l
0.50
52
480
8
73
1.10
0.16
1.4
1.5
—
—
—
0
0
215
2110
1.05
0.14
3.2
3.4
—
—
—
0
0
8
99
0.80
0.14
1.5
1.7
—
—
—
0
0
46
484
0.94
0.11
1.6
1.7
1607.8
1238.1
nmol/l
1.16
33
364
12
135
0.89
0.10
1.6
1.4
—
—
—
0
0
6
56
1.07
0.08
5.5
1.3
—
1.2
—
0
6
6
56
1.07
0.08
4.8
2.5
21.4
24.2
mmol/l
—
6
49
15
136
1.11
0.08
6.8
9.3
1.3
1.5
%
0.94
15
136
103
1053
0.97
0.07
3.4
3.3
48.1
36.7
ng/l
0.19
67
663
12
108
1.11
0.07
1.2
1.3
—
—
—
0
0
36
344
1.05
0.07
5.9
5.7
—
—
—
0
0
23
217
1.06
0.06
3.6
1.8
—
—
—
0
0
11
120
0.91
0.05
1.9
1.6
—
—
—
0
0
14
130
1.08
0.04
6.0
6.1
24.9
24.9
mmol/l
0.02
14
130
73
715
1.03
0.04
2.8
3.0
1451.4
1002.3
ng/l
0.40
64
588
56
546
1.03
0.04
1.8
1.5
—
—
—
0
0
44
427
1.03
0.04
2.4
2.0
—
—
—
0
0
12
129
0.93
0.03
1.4
1.4
—
—
—
0
0
33
341
0.96
0.03
4.1
4.4
30.0
30.9
%
0.19
26
223
29
280
1.04
0.03
3.4
1.9
—
—
—
0
0
19
181
1.05
0.03
5.7
1.8
64.7
67.9
g/l
0.80
19
163
12
112
1.07
0.03
1.1
1.6
—
212.5
—
0
8
12
113
1.06
0.02
2.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
59
0.85
0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
140.0
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_SHORT_LOWER_EXALLC – Benign neoplasm: Short bones of lower limb
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).