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Carcinoma in situ of oral cavity, oesophagus and stomach

CD2_INSITU_ORAL_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D00
  • Cause of death: ICD-10 D00

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D00-D09
Name in latin
Carcinoma in situ cavitatis oris, oesophagi sive ventriculi

Similar endpoints

List of similar endpoints to Carcinoma in situ of oral cavity, oesophagus and stomach based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 187 57 130
Unadjusted period prevalence (%) 0.05 0.02 0.06
Median age at first event (years) 69.05 70.30 68.50

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
169
Matched controls
1689
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
49.4
45
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.0
25.3
95
298
D00.2
ICD-10 Finland
Carcinoma in situ: Stomach
+∞
23.5
22
*
D00.1
ICD-10 Finland
Carcinoma in situ: Oesophagus
+∞
22.4
21
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
50.7
22.1
26
6
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
21.3
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
8.1
20.6
50
83
D00.00
ICD-10 Finland
Cancer in situ on the lip red border
+∞
18.0
17
*
H02AB02
ATC
dexamethasone; systemic
39.6
17.1
21
6
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
29.6
16.0
21
8
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.4
15.1
67
221
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
14.8
14
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
14.8
14
*
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
163.3
14.7
15
*
K22.7
ICD-10 Finland
Barrett oesophagus
21.5
14.6
21
11
WX402
NOMESCO Finland
General anaesthesia
6.0
14.1
41
85
D00.06
ICD-10 Finland
Cancer in situ in another part of the tongue
+∞
13.7
13
*
JN4BD
NOMESCO Finland
Extensive body CT
8.4
13.5
30
42
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
43.8
13.4
16
*
N02AA05
ATC
oxycodone; systemic
5.0
13.2
46
117
D00.09
ICD-10 Finland
Unspecified cancer in situ in oral cavity and throat
+∞
12.6
12
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
12.6
12
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
139.7
12.6
13
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
14.9
12.3
20
15
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
69.8
11.8
13
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
13.1
11.7
20
17
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
11.6
11
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
11.6
11
*
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
128.2
11.6
12
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
128.2
11.6
12
*
UJD02
NOMESCO Finland
Gastroscopy
7.6
11.5
27
41
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
64.0
10.8
12
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
15.6
10.7
17
12
EKA10
NOMESCO Finland
Biopsy of cheek
15.6
10.7
17
12
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
9.8
10.6
21
24
WX002
NOMESCO Finland
Sedation and analgesia
3.7
10.6
53
187
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
+∞
10.5
10
*
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
+∞
10.5
10
*
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
+∞
10.5
10
*
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
+∞
10.5
10
*
R4190
NOMESCO Finland
Nutritional therapy
34.9
10.5
13
*
JN4AD
NOMESCO Finland
Body CT examination
11.1
10.3
19
19
JDB10
NOMESCO Finland
Percutaneous gastrostomy
27.9
10.0
13
5
Z51.5
ICD-10 Finland
Palliative care
12.4
9.8
17
15
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
32.0
9.5
12
*
D00.04
ICD-10 Finland
In situ cancer of the floor of the mouth
+∞
9.5
9
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
9.5
9
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
9.5
9
*
C159, 8148, 2
ICD-O-3
NA
+∞
9.5
9
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
16.8
9.2
14
9
UJC12
NOMESCO Finland
Flexible oesophagoscopy
38.9
9.1
11
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
8.4
8.9
19
25
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
52.7
8.8
10
*
EAA10
NOMESCO Finland
Excision of lesion of lip
52.7
8.8
10
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
21.3
8.6
12
6
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
29.2
8.6
11
*
ECA20
NOMESCO Finland
Biopsy of gingiva
29.2
8.6
11
*
107
Kela drug reimbursment
Pernicious anaemia
10.2
8.5
16
17
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
8.4
8
*
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
+∞
8.4
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
8.4
8
*
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
+∞
8.4
8
*
K13.78
ICD-10 Finland
Other change in the oral mucosa
13.9
8.0
13
10
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
47.1
7.8
9
*
B03BA03
ATC
hydroxocobalamin; parenteral
5.1
7.8
24
53
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
26.3
7.7
10
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
83.5
7.5
8
*
A04AA01
ATC
ondansetron; systemic, rectal
10.0
7.4
14
15
SBA00
NOMESCO Finland
Microbiological examinations
11.6
7.4
13
12
L57.0
ICD-10 Finland
Actinic keratosis
4.8
7.4
24
56
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
+∞
7.3
7
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.3
7
*
8140/3-C16.9
ICD-O-3
Adenocarcinoma, NOS, of stomach, NOS
+∞
7.3
7
*
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
+∞
7.3
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
7.3
7
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
+∞
7.3
7
*
D00.01
ICD-10 Finland
In situ cancer of the mucous membrane of the cheek
+∞
7.3
7
*
TEA00
NOMESCO Finland
Biopsy of lip
16.6
7.3
11
7
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.6
6.8
23
56
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
41.7
6.8
8
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
6.8
29
88
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
10.6
6.6
12
12
A07AA02
ATC
nystatin; oral
5.0
6.5
20
44
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.8
6.5
27
80
K13.29
ICD-10 Finland
Indefinite leukoplakia
72.3
6.5
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
72.3
6.5
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
6.4
47
208
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
6.3
6
*
D00.05
ICD-10 Finland
In situ cancer of the pharyngeal part of the tongue
+∞
6.3
6
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
+∞
6.3
6
*
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
+∞
6.3
6
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
6.3
6
*
C160, 8148, 2
ICD-O-3
NA
+∞
6.3
6
*
C16.00
ICD-10 Finland
Cardia
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
EAA30
NOMESCO Finland
Partial excision of lower lip
+∞
6.3
6
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
+∞
6.3
6
*
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
9.1
6.2
12
14
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.2
6.2
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
36
12.99
36.08
1.4
1.2
—
—
—
0
0
43
88
6.05
21.13
1.6
1.1
—
—
—
0
0
48
109
5.58
21.09
2.8
2.1
0.2
0.2
g/l
0.52
48
90
93
361
4.14
20.57
3.7
1.6
—
—
—
0
0
90
349
4.04
19.78
3.9
2.1
—
—
—
0
0
55
164
4.33
17.10
3.4
1.2
—
—
—
0
0
110
526
3.65
17.01
5.9
3.6
—
—
—
0
0
46
168
3.31
10.22
6.8
5.4
0.3
1.6
mmol/l
1.64
35
127
102
578
2.68
10.01
9.5
10.9
1.1
1.4
inr
—
10
158
33
103
3.68
9.29
6.9
6.7
—
—
—
0
0
24
62
4.29
8.73
9.1
8.1
—
—
—
0
0
73
381
2.50
8.11
1.6
1.6
17.2
20.5
nmol/l
1.71
64
327
102
625
2.39
7.87
6.9
4.6
1.2
1.2
mmol/l
1.17
93
552
74
394
2.45
7.83
6.5
3.9
—
—
—
0
0
48
209
2.74
7.67
2.4
1.6
—
—
—
0
0
31
109
3.21
7.21
6.9
5.4
1.7
1.4
mmol/l
0.30
31
103
100
627
2.28
7.08
7.1
5.1
0.0
0.0
e9/l
0.06
84
530
101
638
2.27
7.00
7.2
5.1
2.5
1.8
e9/l
0.43
87
544
99
623
2.25
6.89
7.1
5.1
0.7
0.6
e9/l
1.13
83
520
106
686
2.26
6.89
12.7
6.1
4.7
4.4
e9/l
0.47
96
589
76
429
2.30
6.87
7.1
5.2
—
—
—
0
0
21
61
3.75
6.50
8.6
7.8
23.8
24.9
mmol/l
1.07
21
50
67
369
2.27
6.33
3.3
2.2
3.0
3.0
mg/l
0.04
59
305
98
629
2.17
6.33
2.4
2.0
96.9
91.4
pmol/l
0.41
59
334
74
425
2.23
6.32
4.0
2.1
2.3
2.3
mmol/l
0.04
64
351
100
648
2.17
6.29
7.3
5.3
0.2
0.2
e9/l
2.08
87
551
19
53
3.88
6.22
1.8
2.0
3.1
2.5
ug/l
0.12
13
43
93
589
2.15
6.17
7.5
5.6
25.5
27.0
%
0.41
86
534
90
563
2.15
6.16
6.7
5.4
0.7
0.7
%
0.21
84
514
19
54
3.80
6.06
3.1
2.0
262.3
443.9
ug/l
0.60
19
47
91
575
2.13
6.04
7.4
5.4
2.3
3.1
%
3.61
85
522
92
585
2.13
5.99
7.3
5.3
58.7
57.7
%
0.25
86
535
91
578
2.12
5.93
8.2
5.7
8.5
8.9
%
0.64
85
526
43
200
2.49
5.91
2.7
2.3
2.3
2.3
g/l
0.27
38
182
40
190
2.41
5.22
2.8
2.3
17.7
22.1
%
1.39
30
168
33
150
2.46
4.72
1.2
1.3
537.1
447.0
titre
—
7
40
32
144
2.47
4.67
2.1
2.1
73.3
64.5
e9/l
0.78
19
116
79
515
1.92
4.47
3.5
2.7
123.3
136.2
ug/l
0.28
73
465
7
6
12.05
4.31
8.6
1.7
4.0
5.9
nmol/l
—
7
6
7
6
12.05
4.31
2.3
2.2
—
—
—
0
0
49
279
2.02
4.04
9.2
4.6
—
—
—
0
0
23
95
2.62
3.99
1.6
1.5
—
—
—
0
0
25
112
2.42
3.68
1.6
1.2
—
—
—
0
0
27
127
2.32
3.57
1.4
1.6
—
—
—
0
0
32
164
2.15
3.45
2.3
2.6
3.2
6.2
ug/l
2.28
25
140
17
65
2.78
3.41
1.5
1.4
—
—
—
0
0
21
90
2.50
3.39
5.0
3.1
6.6
3.7
e9/l
1.03
14
61
124
986
1.76
3.29
5.3
4.0
17.4
12.6
mm/h
1.98
119
882
23
439
0.46
3.17
3.3
3.4
—
—
—
0
0
13
45
3.03
3.09
1.2
1.7
—
—
—
0
0
8
16
5.17
3.08
1.4
1.2
—
—
—
0
0
5
5
10.22
2.99
1.0
1.6
—
—
—
0
0
22
103
2.29
2.94
1.6
1.4
—
—
—
0
0
6
9
6.84
2.89
2.0
1.0
—
—
—
0
0
55
360
1.75
2.87
3.7
2.8
—
—
—
0
0
38
224
1.87
2.78
1.7
1.7
29.4
29.4
s
0.01
38
214
30
167
1.95
2.60
1.8
1.4
—
—
—
0
0
82
614
1.60
2.50
5.1
4.2
39.5
49.1
ng/l
0.36
66
470
57
390
1.66
2.50
3.8
3.0
—
—
—
0
0
22
112
2.09
2.42
5.8
3.6
—
—
—
0
0
6
12
5.13
2.42
2.5
4.0
—
—
—
0
0
56
385
1.65
2.40
3.7
2.8
0.3
0.4
e6/l
0.39
44
282
45
293
1.71
2.36
1.6
1.6
1.4
1.3
mg/l
0.11
37
218
58
410
1.60
2.21
3.8
3.0
86.1
250.0
e6/l
0.49
48
314
16
75
2.24
2.15
5.8
3.1
—
—
—
0
0
46
309
1.65
2.14
5.1
3.6
155.7
136.9
ng/l
0.07
40
254
23
126
1.94
2.09
6.5
2.9
—
—
—
0
0
113
935
1.53
2.09
3.3
3.6
14.8
15.1
pmol/l
0.58
103
829
56
402
1.56
1.97
3.1
3.1
7.4
7.4
ph
—
5
63
64
475
1.53
1.94
4.2
3.5
73.0
94.2
e6/l
0.21
48
339
47
325
1.60
1.94
1.7
1.8
1164.8
1171.5
nmol/l
0.02
34
254
8
28
2.94
1.88
3.7
1.3
—
—
—
0
0
43
293
1.61
1.88
1.2
1.3
—
—
—
0
0
7
23
3.12
1.81
1.3
1.2
20.7
15.2
u/ml
—
7
23
24
143
1.78
1.71
3.7
3.4
—
—
—
0
0
19
105
1.90
1.70
5.8
3.1
—
7.4
—
0
10
10
43
2.40
1.63
3.3
1.3
23.4
36.3
mg/l
—
10
36
6
20
3.06
1.59
2.8
1.2
—
—
—
0
0
148
1331
1.54
1.58
32.8
13.7
33.6
24.5
mg/l
2.10
135
1045
21
124
1.78
1.55
3.1
3.2
—
—
—
0
0
7
27
2.65
1.53
3.6
1.3
—
—
—
0
0
25
157
1.68
1.50
2.7
1.8
—
—
—
0
0
12
60
2.07
1.41
1.4
1.3
—
—
—
0
0
17
98
1.81
1.36
1.8
1.3
—
—
—
0
0
41
299
1.48
1.32
3.9
3.9
—
—
—
0
0
10
49
2.10
1.24
1.8
1.8
—
—
—
0
0
12
65
1.90
1.16
1.0
1.4
—
—
—
0
0
7
30
2.38
1.13
3.3
1.7
25.0
31.0
umol/l
—
7
23
17
105
1.68
1.10
3.1
1.3
—
—
—
0
0
8
41
1.99
1.10
1.3
1.1
—
—
—
0
0
8
41
1.99
1.10
1.3
1.3
—
—
—
0
0
5
21
2.42
1.09
1.2
1.1
—
—
—
0
0
14
82
1.76
1.08
2.1
2.4
—
—
—
0
0
132
1196
1.35
1.08
4.7
4.4
2.1
2.0
mu/l
0.42
120
1057
5
22
2.31
1.04
5.0
2.3
—
—
—
0
0
12
70
1.76
0.95
5.8
3.3
—
—
—
0
0
104
923
1.29
0.92
5.7
4.1
—
—
—
0
0
57
468
1.31
0.91
3.5
3.4
993.0
414.8
mg/l
0.26
40
312
60
499
1.30
0.87
3.8
4.2
5.9
8.8
mg/mmol
0.59
44
327
6
31
1.97
0.85
1.5
1.2
—
—
—
0
0
48
389
1.31
0.84
2.9
2.6
19155.8
9532.7
umol/l
0.32
42
338
13
81
1.65
0.83
2.8
3.4
—
—
—
0
0
28
209
1.40
0.82
1.4
1.3
3.0
2.9
g/l
0.06
15
124
57
478
1.28
0.77
3.4
3.2
7.1
7.6
mmol/l
0.34
49
400
0
28
0.00
0.76
0.0
1.9
—
—
—
0
0
9
58
1.58
0.71
1.3
1.3
73.8
263.4
u/ml
—
9
52
27
346
0.74
0.69
3.6
3.3
—
—
—
0
0
126
1168
1.24
0.67
34.3
14.7
35.6
40.0
%
3.05
79
740
13
87
1.53
0.65
1.8
1.1
—
—
—
0
0
5
29
1.74
0.64
2.0
2.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.6
—
—
—
0
0
65
573
1.21
0.55
11.4
8.5
0.0
0.0
e9/l
0.74
49
460
57
498
1.21
0.53
4.0
3.8
—
—
—
0
0
18
137
1.35
0.49
1.4
1.5
—
—
—
0
0
7
49
1.44
0.46
2.6
1.8
—
—
—
0
0
43
373
1.20
0.43
1.8
2.6
0.7
0.8
ug/l
0.37
25
257
5
33
1.53
0.41
1.0
1.9
—
—
—
0
0
5
34
1.48
0.40
1.8
3.2
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
457.8
—
0
10
0
18
0.00
0.40
0.0
2.3
—
34.6
—
0
18
9
66
1.38
0.39
2.2
3.9
24.2
24.8
mmol/l
—
9
59
12
90
1.36
0.37
2.8
2.5
—
—
—
0
0
6
42
1.44
0.36
1.8
2.5
—
—
—
0
0
132
1263
1.15
0.35
7.6
6.6
42.4
41.3
mmol/mol
0.70
120
1157
28
240
1.20
0.32
1.6
1.2
0.7
1.6
u/ml
—
8
61
144
1390
1.16
0.32
27.6
13.1
—
—
—
0
0
76
706
1.13
0.31
5.5
3.9
1.7
2.1
ug/l
0.64
70
626
146
1413
1.15
0.30
37.8
16.2
85.4
84.1
umol/l
0.21
146
1413
12
94
1.30
0.29
3.3
4.7
3.2
0.8
%
—
5
26
128
1327
0.89
0.28
5.6
5.0
6.3
6.1
mmol/l
0.63
119
1183
8
63
1.28
0.28
1.5
2.6
4.0
4.2
pmol/l
—
8
54
31
348
0.87
0.25
4.4
4.1
0.0
0.0
estimate
—
6
96
103
1075
0.91
0.24
39.8
16.1
14.3
13.8
%
2.74
103
1046
5
38
1.32
0.23
1.4
1.6
—
—
—
0
0
68
640
1.10
0.21
4.1
3.8
0.0
0.0
estimate
—
6
96
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
485.9
—
0
7
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
37
339
1.11
0.19
1.5
1.8
566.2
419.3
pmol/l
0.46
27
273
7
59
1.19
0.18
9.0
11.5
—
—
—
0
0
10
82
1.23
0.17
1.5
1.2
—
42.3
—
0
8
22
199
1.12
0.14
1.3
1.3
2.0
14.3
u/ml
—
5
67
66
634
1.06
0.12
4.0
3.8
0.0
0.0
estimate
—
6
105
100
976
1.05
0.10
5.2
4.2
—
—
—
0
0
12
108
1.12
0.07
1.2
1.4
—
—
—
0
0
65
632
1.04
0.07
5.6
5.1
0.0
0.0
estimate
—
6
103
27
258
1.05
0.05
6.7
4.5
—
—
—
0
0
129
1302
0.97
0.04
4.8
4.8
1.4
1.4
mmol/l
0.35
119
1172
127
1263
1.02
0.01
4.3
4.3
1.4
1.3
mmol/l
0.74
116
1126
22
216
1.02
0.00
1.3
1.3
30.9
33.2
iu/ml
—
8
70
45
449
1.00
0.00
6.9
4.2
—
—
—
0
0
135
1349
1.00
0.00
5.3
5.4
2.3
2.6
mmol/l
2.50
126
1218
131
1312
0.99
0.00
4.8
4.8
4.2
4.4
mmol/l
1.47
121
1189
0
8
0.00
0.00
0.0
2.3
—
2393.8
—
0
8
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
247.8
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
70
1.00
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_ORAL_EXALLC – Carcinoma in situ of oral cavity, oesophagus and stomach

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).