This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Carcinoma in situ of oral cavity, oesophagus and stomach
CD2_INSITU_ORAL_EXALLC
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D00-D09
- Name in latin
- Carcinoma in situ cavitatis oris, oesophagi sive ventriculi
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of oral cavity, oesophagus and stomach
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of oral cavity, oesophagus and stomach
- In situ neoplasms
- In situ neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 187 | 57 | 130 |
| Unadjusted period prevalence (%) | 0.05 | 0.02 | 0.06 |
| Median age at first event (years) | 69.05 | 70.30 | 68.50 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 169
- Matched controls
- 1689
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
49.4
45
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.0
25.3
95
298
D00.2
ICD-10 Finland
Carcinoma in situ: Stomach
+∞
23.5
22
*
D00.1
ICD-10 Finland
Carcinoma in situ: Oesophagus
+∞
22.4
21
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
50.7
22.1
26
6
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
+∞
21.3
20
*
A03FA01
ATC
metoclopramide; systemic, rectal
8.1
20.6
50
83
D00.00
ICD-10 Finland
Cancer in situ on the lip red border
+∞
18.0
17
*
H02AB02
ATC
dexamethasone; systemic
39.6
17.1
21
6
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
29.6
16.0
21
8
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.4
15.1
67
221
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
+∞
14.8
14
*
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
+∞
14.8
14
*
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
163.3
14.7
15
*
K22.7
ICD-10 Finland
Barrett oesophagus
21.5
14.6
21
11
WX402
NOMESCO Finland
General anaesthesia
6.0
14.1
41
85
D00.06
ICD-10 Finland
Cancer in situ in another part of the tongue
+∞
13.7
13
*
JN4BD
NOMESCO Finland
Extensive body CT
8.4
13.5
30
42
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
43.8
13.4
16
*
N02AA05
ATC
oxycodone; systemic
5.0
13.2
46
117
WF002
NOMESCO Finland
Radical radiotherapy
+∞
12.6
12
*
D00.09
ICD-10 Finland
Unspecified cancer in situ in oral cavity and throat
+∞
12.6
12
*
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
139.7
12.6
13
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
14.9
12.3
20
15
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
69.8
11.8
13
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
13.1
11.7
20
17
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
+∞
11.6
11
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
11.6
11
*
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
128.2
11.6
12
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
128.2
11.6
12
*
UJD02
NOMESCO Finland
Gastroscopy
7.6
11.5
27
41
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
64.0
10.8
12
*
EKA10
NOMESCO Finland
Biopsy of cheek
15.6
10.7
17
12
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
15.6
10.7
17
12
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
9.8
10.6
21
24
WX002
NOMESCO Finland
Sedation and analgesia
3.7
10.6
53
187
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
+∞
10.5
10
*
EJB30
NOMESCO Finland
Excision of lesion of floor of mouth
+∞
10.5
10
*
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
+∞
10.5
10
*
K13.28
ICD-10 Finland
Other leukoplakia or disorder of epithelium of the palate or tongue
+∞
10.5
10
*
R4190
NOMESCO Finland
Nutritional therapy
34.9
10.5
13
*
JN4AD
NOMESCO Finland
Body CT examination
11.1
10.3
19
19
JDB10
NOMESCO Finland
Percutaneous gastrostomy
27.9
10.0
13
5
Z51.5
ICD-10 Finland
Palliative care
12.4
9.8
17
15
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
32.0
9.5
12
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
9.5
9
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
9.5
9
*
C159, 8148, 2
ICD-O-3
NA
+∞
9.5
9
*
D00.04
ICD-10 Finland
In situ cancer of the floor of the mouth
+∞
9.5
9
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
16.8
9.2
14
9
UJC12
NOMESCO Finland
Flexible oesophagoscopy
38.9
9.1
11
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
8.4
8.9
19
25
EAA10
NOMESCO Finland
Excision of lesion of lip
52.7
8.8
10
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
52.7
8.8
10
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
21.3
8.6
12
6
ECA20
NOMESCO Finland
Biopsy of gingiva
29.2
8.6
11
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
29.2
8.6
11
*
107
Kela drug reimbursment
Pernicious anaemia
10.2
8.5
16
17
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
+∞
8.4
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
8.4
8
*
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
+∞
8.4
8
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
+∞
8.4
8
*
K13.78
ICD-10 Finland
Other change in the oral mucosa
13.9
8.0
13
10
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
47.1
7.8
9
*
B03BA03
ATC
hydroxocobalamin; parenteral
5.1
7.8
24
53
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
26.3
7.7
10
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
83.5
7.5
8
*
A04AA01
ATC
ondansetron; systemic, rectal
10.0
7.4
14
15
SBA00
NOMESCO Finland
Microbiological examinations
11.6
7.4
13
12
L57.0
ICD-10 Finland
Actinic keratosis
4.8
7.4
24
56
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
7.3
7
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
7.3
7
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
+∞
7.3
7
*
8140/3-C16.9
ICD-O-3
Adenocarcinoma, NOS, of stomach, NOS
+∞
7.3
7
*
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
+∞
7.3
7
*
C03.0
ICD-10 Finland
Malignant neoplasm: Upper gum
+∞
7.3
7
*
D00.01
ICD-10 Finland
In situ cancer of the mucous membrane of the cheek
+∞
7.3
7
*
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
+∞
7.3
7
*
TEA00
NOMESCO Finland
Biopsy of lip
16.6
7.3
11
7
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.6
6.8
23
56
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
41.7
6.8
8
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
6.8
29
88
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
10.6
6.6
12
12
A07AA02
ATC
nystatin; oral
5.0
6.5
20
44
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.8
6.5
27
80
K13.29
ICD-10 Finland
Indefinite leukoplakia
72.3
6.5
7
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
72.3
6.5
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
6.4
47
208
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
EAA30
NOMESCO Finland
Partial excision of lower lip
+∞
6.3
6
*
C06.0
ICD-10 Finland
Malignant neoplasm: Cheek mucosa
+∞
6.3
6
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
6.3
6
*
C16.00
ICD-10 Finland
Cardia
+∞
6.3
6
*
EDB00
NOMESCO Finland
Partial excision of mandible
+∞
6.3
6
*
D00.05
ICD-10 Finland
In situ cancer of the pharyngeal part of the tongue
+∞
6.3
6
*
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
+∞
6.3
6
*
C160, 8148, 2
ICD-O-3
NA
+∞
6.3
6
*
C03.1
ICD-10 Finland
Malignant neoplasm: Lower gum
+∞
6.3
6
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
+∞
6.3
6
*
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
9.1
6.2
12
14
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.2
6.2
10
8
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_ORAL_EXALLC – Carcinoma in situ of oral cavity, oesophagus and stomach
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).