No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
180 |
4. Check minimum number of eventsNone |
180 |
5. Include endpointsNone |
180 |
6. Filter based on genotype QC (FinnGen only) |
180 |
Control definitions (FinnGen only)
- Control exclude
- F5_PERSOBEH
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F60
- Name in latin
- Personalitas histrionica
Similar endpoints
↥List of similar endpoints to
Histrionic personality disorder
based on the number of shared cases.
Similar with more cases:
- Specific personality disorders
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1630 | 1108 | 491 |
| Only index persons | 1208 | 870 | 338 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.01 |
| Only index persons | 0.03 | 0.03 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 37.99 | 39.56 | 33.95 |
| Only index persons | 35.62 | 37.32 | 31.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 180 | 130 | 50 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | 30.85 | 30.04 | 32.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 166
- Matched controls
- 1662
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F60.4
ICD-10 Finland
Histrionic personality disorder
+∞
95.2
82
*
30150
ICD-8 Finland
Personality disorders, Hysterical
+∞
73.5
65
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
26.1
52.9
77
53
N05AH04
ATC
quetiapine; oral
14.9
47.9
93
130
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
+∞
41.4
38
*
N05AA02
ATC
levomepromazine; systemic
30.5
37.3
50
23
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
+∞
34.6
32
*
N05BA01
ATC
diazepam; systemic, rectal
10.0
32.1
73
120
N05AH03
ATC
olanzapine; systemic
17.4
31.3
51
41
T36
ICD-10 Finland
Poisoning by systemic antibiotics
23.3
31.0
45
26
N05AX08
ATC
risperidone; systemic
15.0
30.5
53
50
N03AG01
ATC
valproic acid; systemic, rectal
14.4
29.9
53
52
F61.0
ICD-10 Finland
Mixed personality disorders
181.6
29.7
30
*
N06AB04
ATC
citalopram; systemic
7.4
29.6
90
228
F60.9
ICD-10 Finland
Personality disorder, unspecified
167.0
27.5
28
*
N05CD07
ATC
temazepam; oral
9.0
26.7
63
105
N06AX16
ATC
venlafaxine; oral
8.0
25.6
66
126
N05AB03
ATC
perphenazine; systemic, rectal
19.2
25.4
39
26
F32.9
ICD-10 Finland
Depressive episode, unspecified
8.9
24.8
58
94
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
20.3
24.6
37
23
N05BA04
ATC
oxazepam; oral
5.9
24.1
89
271
N06AB03
ATC
fluoxetine; oral
8.1
23.9
60
108
N03AE01
ATC
clonazepam; systemic
12.2
23.8
45
49
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
25.4
23.7
33
16
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
10.7
23.1
47
59
3015A
ICD-9 Finland
Personality disorders, Histrionic personality disorder[HUOMIONHAKUINEN PERSOONALLISUUS]
+∞
22.4
21
*
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
251.7
22.2
22
*
N05AN01
ATC
lithium; oral
25.8
21.7
30
14
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
24.8
20.8
29
14
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
13.3
20.7
37
35
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
21.2
20.5
30
17
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
11.0
19.8
39
45
N05AF03
ATC
chlorprothixene; systemic
26.5
19.8
27
12
F29
ICD-10 Finland
Unspecified nonorganic psychosis
14.4
18.8
32
27
N06AX11
ATC
mirtazapine; oral
4.6
18.7
92
353
N06AA09
ATC
amitriptyline; systemic
7.2
18.7
49
91
N03AX09
ATC
lamotrigine; oral
13.9
18.5
32
28
N04AA02
ATC
biperiden; systemic
27.8
17.9
24
10
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
8.2
17.8
42
66
N05BA06
ATC
lorazepam; systemic, sublingual
12.4
17.1
31
30
N05AX12
ATC
aripiprazole; systemic
15.1
16.4
27
21
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
15.9
15
*
P99
ICPC
Psychological disorders other
17.3
15.4
24
16
N06AX03
ATC
mianserin; oral
9.2
15.0
32
42
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
88.0
14.8
16
*
P29
ICPC
Psychological sympt/compl other
9.0
14.8
32
43
30010
ICD-8 Finland
Neuroses, Hysterical neurosis
+∞
14.8
14
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
40.0
14.8
18
5
F31.8
ICD-10 Finland
Other bipolar affective disorders
19.3
14.8
22
13
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
7.1
14.2
36
62
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
26.6
14.1
19
8
N03AX11
ATC
topiramate; oral
26.6
14.1
19
8
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
6.8
14.1
37
67
N02AX02
ATC
tramadol; systemic, rectal
3.6
13.9
100
491
N05BE01
ATC
buspirone; oral
15.6
13.7
22
16
N05AC02
ATC
thioridazine; oral
23.6
13.7
19
9
F34.1
ICD-10 Finland
Dysthymia
12.5
13.5
24
22
N06AB06
ATC
sertraline; oral
5.5
13.3
42
96
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
31.3
13.2
17
6
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
35.1
12.8
16
5
N05AD01
ATC
haloperidol; systemic
13.1
12.8
22
19
30180
ICD-8 Finland
Personality disorders, Immatura
+∞
12.7
12
*
F60.5
ICD-10 Finland
Anankastic personality disorder
+∞
12.7
12
*
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
17.7
12.5
19
12
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
32.7
11.9
15
5
N06AB10
ATC
escitalopram; oral
3.9
11.9
57
197
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
70.0
11.8
13
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.4
11.7
28
44
F60.8
ICD-10 Finland
Other specific personality disorders
+∞
11.6
11
*
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
11.6
11
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
37.9
11.5
14
*
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
37.9
11.5
14
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.8
11.4
41
107
N05CF01
ATC
zopiclone; oral
3.3
11.4
78
352
P72
ICPC
Schizophrenia
27.2
11.4
15
6
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
17.0
11.1
17
11
N05AD03
ATC
melperone; systemic
23.4
10.9
15
7
N06AA12
ATC
doxepin; systemic
7.0
10.9
27
45
N03AX16
ATC
pregabalin; oral
3.5
10.8
61
237
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
15.6
10.7
17
12
SPAT1240
SPAT
Therapeutic discussion
4.9
10.6
36
88
30188
ICD-8 Finland
Personality disorders, Alia definita
+∞
10.5
10
*
N07BB01
ATC
disulfiram; oral
8.9
10.5
22
28
N05AF05
ATC
zuclopenthixol; systemic
35.0
10.5
13
*
30000
ICD-8 Finland
Neuroses, Anxiety neurosis
35.0
10.5
13
*
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
15.9
10.2
16
11
N05BA12
ATC
alprazolam; oral
4.6
10.1
37
98
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
42.8
10.1
12
*
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
18.1
10.1
15
9
N03AF02
ATC
oxcarbazepine; oral
10.6
10.1
19
20
30041
ICD-8 Finland
Neuroses, Depressiva
21.7
10.0
14
7
N05CD02
ATC
nitrazepam; oral
28.0
10.0
13
5
SPAT1254
SPAT
Administration of medicine
4.1
9.9
41
122
N05AB01
ATC
dixyrazine; systemic
32.1
9.5
12
*
M54.5
ICD-10 Finland
Low back pain
2.9
9.4
77
378
N06AA04
ATC
clomipramine; systemic
12.5
9.3
16
14
P01
ICPC
Feeling anxious/nervous/tense
4.5
9.3
34
90
F10.20
ICD-10 Finland
Alcohol dependence currently independent
39.0
9.1
11
*
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
25.7
9.0
12
5
F39
ICD-10 Finland
Unspecified mood [affective] disorder
15.1
8.9
14
10
F41.1
ICD-10 Finland
Generalized anxiety disorder
7.7
8.9
20
29
N02AA05
ATC
oxycodone; systemic
4.1
8.8
36
106
S06.0
ICD-10 Finland
Concussion
4.3
8.7
33
90
N06AB05
ATC
paroxetine; oral
6.7
8.5
21
35
R06.0
ICD-10 Finland
Dyspnoea
3.0
8.5
60
265
30199
ICD-8 Finland
Personality disorders, Unspecified
+∞
8.4
8
*
3015B
ICD-9 Finland
Personality disorders, Histrionic personality disorder[ITSEAIHEUTETTU HÄIRIÖ,RUUMIILLISIN OIREIN]
+∞
8.4
8
*
A28
ICPC
Limited function/disability NOS
3.9
8.3
35
105
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
15.5
8.3
13
9
N06AX12
ATC
bupropion; oral
7.0
8.3
20
32
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.8
8.2
23
45
N05AA01
ATC
chlorpromazine; systemic, rectal
35.2
8.2
10
*
P19
ICPC
Drug abuse
35.2
8.2
10
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.6
8.1
28
70
C07AA05
ATC
propranolol; systemic
3.1
7.9
50
205
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.3
7.8
20
35
N06AB08
ATC
fluvoxamine; oral
7.8
7.7
17
24
29999
ICD-8 Finland
Unspecified psychosis
26.4
7.7
10
*
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
26.4
7.7
10
*
D01AC02
ATC
miconazole; topical
4.5
7.6
27
69
N03AX12
ATC
gabapentin; oral
3.3
7.5
41
151
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
14.2
7.5
12
9
P18
ICPC
Medication abuse
83.6
7.5
8
*
9690A
ICD-9 Finland
Poisoning by psychotropic agents, Antidepressants
83.6
7.5
8
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
83.6
7.5
8
*
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
83.6
7.5
8
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
11.6
7.4
13
12
N05AF01
ATC
flupentixol; systemic
11.6
7.4
13
12
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
3.3
7.3
40
147
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.7
7.3
33
105
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
+∞
7.3
7
*
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
+∞
7.3
7
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
16.7
7.3
11
7
N06AX21
ATC
duloxetine; oral
4.0
7.3
29
83
AA1AD
NOMESCO Finland
CT of head and brain
2.9
7.3
50
216
P80
ICPC
Personality disorder
31.5
7.2
9
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
31.5
7.2
9
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
31.5
7.2
9
*
E000001
ATC
NA
2.9
7.1
48
202
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
14.6
7.0
11
8
N06AX22
ATC
agomelatine; oral
14.6
7.0
11
8
N06AG02
ATC
moclobemide; oral
6.6
7.0
17
28
A06AD11
ATC
lactulose; oral
3.5
6.9
33
110
F40.1
ICD-10 Finland
Social phobias
17.6
6.8
10
6
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
6.4
6.8
17
29
N06AX26
ATC
vortioxetine; oral
6.4
6.8
17
29
G04BD04
ATC
oxybutynin; oral, transdermal
5.5
6.7
19
38
L28
ICPC
Limited function/disability (L)
3.1
6.7
38
144
Z71.8
ICD-10 Finland
Other specified counselling
2.6
6.7
54
256
SPAT1234
SPAT
Support of social functional capacity
6.2
6.7
17
30
NA1AD
NOMESCO Finland
Cervical spine CT examination
7.1
6.5
15
23
F51.0
ICD-10 Finland
Nonorganic insomnia
3.2
6.5
35
126
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
15.1
6.5
10
7
N05AH02
ATC
clozapine; systemic
15.1
6.5
10
7
SPAT1307
SPAT
Psychosocial counselling and guidance
4.7
6.4
21
50
N89
ICPC
Migraine
11.7
6.4
11
10
V03AA01
ATC
NA
18.9
6.3
9
5
R53
ICD-10 Finland
Malaise and fatigue
2.8
6.3
45
197
A06AC01
ATC
ispaghula (psylla seeds); oral
2.6
6.3
52
248
3000A
ICD-9 Finland
Neurotic disorders, Anxiety states[TARKEMMIN MÄÄRITTELEMÄTÖN AHDISTUNEISUUSHÄIRIÖ]
+∞
6.3
6
*
34598
ICD-8 Finland
Epilepsy, Alia definita
+∞
6.3
6
*
3001A
ICD-9 Finland
Neurotic disorders, Hysteria[KONVERSIOHÄIRIÖ]
+∞
6.3
6
*
79020
ICD-8 Finland
Nervousness and debility, Depression
+∞
6.3
6
*
E970A
ICD-9 Finland
Injury due to legal intervention by firearms
+∞
6.3
6
*
M01AG02
ATC
tolfenamic acid; oral, rectal
3.0
6.2
38
151
R29
ICPC
Respiratory symptom/complaint other
4.7
6.2
20
47
R41.0
ICD-10 Finland
Disorientation, unspecified
9.1
6.2
12
14
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
13.2
6.2
10
8
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
13.2
6.2
10
8
F41.8
ICD-10 Finland
Other specified anxiety disorders
13.2
6.2
10
8
P74
ICPC
Anxiety disorder/anxiety state
6.5
6.2
15
25
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
6.1
33
118
R05
ICPC
Cough
2.6
6.1
51
245
R02
ICPC
Shortness of breath/dyspnoea
3.3
6.1
30
103
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.8
6.0
14
22
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
132
853
3.05
10.27
5.5
4.1
6.4
6.6
mmol/l
0.34
125
787
87
454
2.77
10.23
3.2
2.3
58.0
58.1
u/l
0.00
81
427
12
5
25.54
9.03
16.7
5.2
0.6
0.6
mmol/l
—
12
5
67
331
2.63
8.48
1.4
1.5
18.1
22.5
nmol/l
1.40
57
273
79
425
2.53
8.35
2.7
2.0
138.1
147.3
u/l
0.18
73
407
111
700
2.53
8.30
5.0
6.3
1.2
1.2
mmol/l
0.56
95
606
94
563
2.40
7.69
2.3
1.9
93.6
99.3
pmol/l
0.44
49
262
84
488
2.35
7.26
4.1
3.2
31.0
28.7
u/l
0.23
77
461
116
782
2.36
6.98
5.0
6.2
10.1
10.2
umol/l
0.03
106
748
89
537
2.30
6.96
5.7
3.3
54.1
35.8
ng/l
0.28
65
350
149
1130
2.85
6.86
7.9
7.5
86.0
76.4
u/l
0.99
142
1060
100
643
2.25
6.61
5.2
5.2
1.2
1.2
mmol/l
0.48
91
589
55
275
2.44
6.56
1.9
1.7
434.0
461.5
pmol/l
0.33
44
236
36
146
2.83
6.54
3.3
6.6
5.3
5.1
kpa
0.50
36
141
61
322
2.35
6.43
2.0
1.7
0.8
1.0
mg/l
0.92
45
253
62
332
2.32
6.31
1.7
2.0
2.9
3.4
mg/l
0.60
49
286
38
165
2.65
6.04
18.1
18.8
1.1
1.3
inr
—
6
25
95
618
2.14
5.87
4.4
4.2
35.1
36.0
g/l
0.80
86
584
35
148
2.69
5.85
3.2
6.6
1.9
1.5
mmol/l
0.32
27
116
98
648
2.12
5.77
2.4
2.3
71.8
77.5
nmol/l
1.19
87
573
45
218
2.42
5.68
2.2
1.8
—
—
—
0
0
26
95
3.03
5.65
1.7
1.5
—
—
—
0
0
47
239
2.31
5.29
2.4
1.6
1097.4
1229.7
nmol/l
0.50
35
176
30
125
2.68
5.14
3.2
3.0
6.1
5.7
kpa
1.33
30
125
34
152
2.52
5.06
2.2
1.6
—
—
—
0
0
22
79
3.03
4.92
3.1
2.4
25.6
25.0
mmol/l
0.38
22
79
27
111
2.69
4.74
3.4
2.4
7.2
4.9
ug/l
0.19
21
98
22
81
2.95
4.71
1.5
1.2
—
—
—
0
0
33
152
2.43
4.60
2.2
1.7
—
—
—
0
0
133
1037
2.08
4.49
5.3
2.8
58.8
44.5
u/l
0.89
122
980
43
227
2.17
4.37
2.1
3.1
0.8
0.8
mmol/l
0.91
36
214
143
1167
2.10
3.96
6.2
4.0
14.6
14.7
pmol/l
0.26
134
1056
62
388
1.91
3.91
3.3
2.9
570.9
1144.0
ng/l
1.76
49
328
8
12
6.92
3.71
13.0
21.8
1355.1
1291.7
nmol/l
—
8
12
77
525
1.82
3.67
4.3
3.0
—
—
—
0
0
35
182
2.15
3.66
9.2
6.5
—
—
—
0
0
24
106
2.46
3.64
3.3
2.5
4.2
4.4
kpa
0.18
24
106
19
75
2.71
3.60
4.2
3.0
48.8
48.6
%
0.01
19
75
112
858
1.81
3.58
10.2
10.0
4.4
4.0
e9/l
0.98
97
761
20
84
2.55
3.37
4.0
6.8
0.7
0.7
%
0.15
20
84
20
84
2.55
3.37
4.0
6.8
2.6
1.3
%
2.16
20
84
137
1134
1.87
3.20
4.0
4.1
12.3
10.9
mm/h
0.70
122
1043
18
75
2.56
3.08
2.7
3.1
5.2
5.2
kpa
0.09
18
67
6
8
7.71
3.08
1.5
2.1
—
—
—
0
0
159
1393
2.21
3.02
7.6
4.7
1.7
1.9
mu/l
1.71
147
1274
30
164
2.00
2.74
2.3
1.9
—
—
—
0
0
70
498
1.66
2.69
2.4
3.2
2.4
2.4
mmol/l
0.07
59
438
41
255
1.79
2.54
6.0
3.1
12.7
139.0
ng/l
2.00
27
191
157
1393
1.99
2.51
7.4
5.4
39.4
39.4
mmol/mol
0.01
143
1306
58
400
1.66
2.49
6.7
3.6
0.0
0.0
estimate
0.00
20
130
26
140
2.00
2.48
5.2
3.3
—
—
—
0
0
9
27
3.45
2.43
2.1
2.6
26.6
25.2
mmol/l
—
9
21
31
179
1.88
2.42
2.7
2.1
—
—
—
0
0
51
342
1.69
2.42
1.5
1.2
0.5
1.0
u/ml
1.22
15
90
6
12
5.13
2.42
12.5
14.3
852.2
771.5
nmol/l
—
6
12
35
220
1.73
2.08
1.9
2.1
12.1
13.2
umol/l
0.41
29
207
164
1502
2.03
2.00
21.8
12.9
21.7
21.8
mg/l
0.01
143
1165
57
412
1.56
1.97
3.8
2.9
0.3
0.4
e6/l
0.45
48
298
7
22
3.27
1.90
1.4
1.9
—
—
—
0
0
21
117
1.90
1.84
1.9
3.2
56.1
70.6
ng/l
0.86
16
102
9
35
2.65
1.83
1.3
1.2
—
—
—
0
0
7
23
3.12
1.82
1.1
1.3
—
—
—
0
0
30
192
1.68
1.68
2.1
2.1
18.6
22.4
%
0.95
24
174
12
57
2.18
1.59
2.1
2.0
—
—
—
0
0
19
108
1.85
1.58
2.7
2.4
83.5
63.8
ml/min/173m2
—
10
44
15
79
1.98
1.54
2.0
1.5
—
—
—
0
0
16
87
1.92
1.51
1.3
1.3
—
—
—
0
0
87
716
1.42
1.50
4.6
3.7
—
—
—
0
0
30
198
1.62
1.50
1.9
2.1
2.4
2.4
g/l
0.11
23
184
10
45
2.29
1.49
1.1
1.2
—
—
—
0
0
10
45
2.29
1.49
1.1
1.2
—
—
—
0
0
14
74
1.97
1.43
4.2
2.1
1.6
1.4
%
0.32
14
74
51
384
1.46
1.41
2.3
2.6
340.4
7563.6
umol/l
2.27
46
333
11
54
2.10
1.36
1.8
1.9
—
—
—
0
0
28
188
1.58
1.31
4.6
4.1
30.2
32.3
%
0.51
16
118
26
172
1.60
1.30
1.7
2.5
4.4
6.2
umol/l
1.01
19
150
89
751
1.37
1.26
6.2
3.5
0.0
0.0
estimate
0.00
18
137
81
678
1.35
1.19
3.1
2.5
93.1
93.8
ug/l
0.01
70
631
18
111
1.69
1.17
1.3
2.5
67.2
67.0
g/l
0.04
13
100
89
762
1.33
1.10
7.2
3.5
0.0
0.0
estimate
0.00
19
128
46
358
1.38
1.05
2.0
2.1
—
—
—
0
0
168
1601
1.74
1.04
24.0
14.6
74.3
73.0
umol/l
0.18
168
1601
9
50
1.84
0.98
2.3
1.6
—
—
—
0
0
156
1467
1.48
0.98
5.6
4.3
6.0
5.9
mmol/l
0.70
140
1346
9
52
1.77
0.94
1.3
1.6
—
—
—
0
0
33
249
1.40
0.90
3.0
2.6
1.9
1.1
e6/l
0.59
24
137
87
759
1.28
0.89
8.8
4.9
0.0
0.0
estimate
0.00
20
135
6
31
1.97
0.85
1.2
1.2
—
53.5
—
0
5
6
31
1.97
0.85
1.2
1.6
—
—
—
0
0
8
47
1.73
0.82
3.5
2.5
—
—
—
0
0
11
66
1.71
0.80
1.5
1.8
3.6
2.4
mg/l
0.33
11
46
12
74
1.67
0.80
3.2
4.7
27.5
25.6
mmol/l
0.36
12
74
0
26
0.00
0.79
0.0
1.4
—
7.5
—
0
17
13
84
1.59
0.74
2.3
1.6
—
—
—
0
0
9
58
1.58
0.71
1.2
1.3
—
—
—
0
0
68
589
1.25
0.71
7.5
3.5
—
—
—
0
0
7
41
1.74
0.71
2.0
1.6
—
—
—
0
0
150
1422
1.33
0.69
18.6
11.8
84.6
83.0
ml/min/173m2
0.35
129
1147
5
27
1.88
0.69
1.6
1.5
—
—
—
0
0
5
27
1.88
0.69
1.6
1.5
—
—
—
0
0
15
104
1.48
0.65
2.4
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
3.8
—
90.3
—
0
20
9
60
1.53
0.55
1.1
1.4
—
—
—
0
0
28
225
1.29
0.53
4.1
2.8
3.2
3.4
e6/l
0.07
20
117
156
1502
1.29
0.51
4.6
4.2
4.6
4.7
mmol/l
0.62
139
1401
166
1612
1.38
0.50
13.3
10.1
24.8
25.5
u/l
0.25
156
1561
7
49
1.45
0.46
1.0
1.1
—
10.8
—
0
8
36
307
1.22
0.43
1.8
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
1.2
—
0
8
158
1532
1.26
0.41
5.2
4.7
2.8
2.8
mmol/l
0.07
140
1417
27
320
0.82
0.39
1.3
1.4
—
—
—
0
0
5
36
1.40
0.38
1.6
1.8
—
—
—
0
0
134
1391
0.86
0.35
20.5
13.4
36.6
40.1
%
1.90
80
1044
149
1444
1.18
0.33
4.0
3.8
1.5
1.3
mmol/l
2.54
128
1338
11
83
1.35
0.33
1.2
1.0
—
—
—
0
0
6
47
1.29
0.32
1.5
2.9
—
—
—
0
0
7
57
1.24
0.29
2.0
2.5
—
—
—
0
0
153
1495
1.16
0.24
4.5
4.2
1.4
1.5
mmol/l
1.80
135
1386
105
1006
1.10
0.24
3.6
3.0
—
—
—
0
0
5
42
1.20
0.21
1.4
3.5
46.9
39.9
mg/l
—
5
35
5
42
1.20
0.21
1.4
3.5
38.6
27.3
mg/l
—
5
35
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
31
279
1.13
0.21
1.1
1.3
1.6
10.8
u/ml
2.86
13
115
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
6.6
—
0
7
31
291
1.08
0.10
1.2
1.3
12.1
33.6
iu/ml
—
10
98
5
61
0.81
0.08
1.6
1.5
—
—
—
0
0
23
244
0.93
0.07
4.3
4.0
26.9
20.9
%
0.89
13
114
42
405
1.05
0.06
1.6
1.6
1.3
1.3
mmol/l
0.00
33
352
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
9.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
16.8
—
0
8
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint F5_HISPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_HISPER | 3.111 [2.32, 4.18] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.171 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 395 females with F5_HISPER died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have F5_HISPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.352% | No data |
| 5 | 1.577% | No data |
| 10 | 4.391% | No data |
| 15 | 7.889% | No data |
| 20 | 13.936% | No data |
Relationships between endpoints
↥Index endpoint: F5_HISPER – Histrionic personality disorder
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data